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Other Biomedical Engineering and Bioengineering Commons™
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Articles 31 - 32 of 32
Full-Text Articles in Other Biomedical Engineering and Bioengineering
Zein Nanospheres For Gene Delivery, Mary C. Regier
Zein Nanospheres For Gene Delivery, Mary C. Regier
Department of Agricultural and Biological Systems Engineering: Dissertations, Theses, and Student Research
Particulates incorporating DNA provide for protection and sustained release of DNA, and thus are promising candidates for DNA delivery systems. Among the routes of administration for gene delivery, the oral route is perhaps the most appealing as it is associated with patient comfort and compliance and allows for targeting to intestinal targets for therapeutic and vaccination applications. With the goal of realizing the potential of an oral DNA delivery system, zein, a hydrophobic protein from corn that is biocompatible and degraded enzymatically, was investigated. This thesis describes the formulation of zein nanospheres encapsulating DNA by a coacervation technique and their …
Fracture Of Bone Using Microindentation, Séverine Vennin
Fracture Of Bone Using Microindentation, Séverine Vennin
Department of Engineering Mechanics: Dissertations, Theses, and Student Research
Osteoporosis is a current disease which is especially of concern to post-menopausal women. It is characterized by a decrease of bone density and an increase in the risk of fracture. Interest in the fracture mechanisms with respect to the underlying biological structure of the bone is of great interest to researchers in this field. In this thesis, a new method based on microindentation on rat femurs was developed to determine the relation between the viscoelastic and the fracture properties of bone. The main goal is to measure the viscoelastic properties by using a dynamic mechanical analysis indentation method and then …