Biomedical Devices and Instrumentation Commons^™

Quantitative Fluorescence Imaging Using A Paired Agent Approach For Improving Surgical Decision Making, Sanjana Pannem

Dartmouth College Ph.D Dissertations

Surgical resection remains to be the cornerstone of treatment for most solid tumors, where the primary objective is to remove all visible and microscopic disease. However, the extent of tumor resection is inherently limited by the surgeon’s ability to distinguish tumor from normal tissue, intraoperatively. As a result, positive surgical margins (PSM), where residual tumor remains after surgery, are a common occurrence and are associated with increased recurrence, need for adjuvant therapies, dismal patient outcomes, and high healthcare costs.

Fluorescence guided surgery (FGS) has emerged as a promising technique to enhance intraoperative visualization of tumors and may help reduce the …

Delivery Method For Dissolvable Staples, Brian Nguyen, Colleen Kroah, Bethany Fogle, Sean Brown

Williams Honors College, Honors Research Projects

Surgical staples play a vital role in modern medicine by enabling efficient wound closure and tissue repair. However, traditional metal staples often require removal, increasing patient discomfort and the risk of infection. Dissolvable staples offer a promising alternative, eliminating the need for removal while maintaining secure wound closure. Despite their potential, current delivery systems for dissolvable staples face significant challenges, including inconsistent deployment, lack of precision, and inadequate integration with surgical workflows.

Developing an optimized delivery system is critical to maximizing the benefits of dissolvable staples. Such a system must ensure reliable performance, precision, and ease of use while maintaining …

Rod Bend Approximator For Minimally Invasive Spinal Surgery, Amanda Hansell, Anise Ghandchi, Shervin Moghimi

Biomedical Engineering

This Final Report will go over the project deliverables and future steps in the making of a rod bending approximator tool by the Cal Poly Senior Design team for the client SeaSpine. The latest designs and research done regarding minimally invasive surgery (MIS) is covered including the impediments with the current methods. SeaSpine presented the need to our team for an approximating tool within the MIS procedure. Our team began project planning through task generation and schedule development. Once the product definition was fully understood, competition was evaluated and engineering specifications were created for the project. A conceptual design was …

In Vitro Mitral Valve Model With Unrestricted Ventricular Access: Using Vacuum To Close The Valve And Enable Static Trans-Mitral Pressure, Sam E. Stephens, Alexander J. Kammien, Jacob C. Paris, Alexis P. Applequist, Neil B. Ingels, Hanna K. Jensen, Drew E. Rodgers, Charles R. Cole, Jonathan F. Wenk, Morten O. Jensen

Biomedical Engineering Faculty Publications and Presentations

Current in vitro models of the left heart establish the pressure difference required to close the mitral valve by sealing and pressurizing the ventricular side of the valve, limiting important access to the subvalvular apparatus. This paper describes and evaluates a system that establishes physiological pressure differences across the valve using vacuum on the atrial side. The subvalvular apparatus is open to atmospheric pressure and accessible by tools and sensors, establishing a novel technique for experimentation on atrioventricular valves. Porcine mitral valves were excised and closed by vacuum within the atrial chamber. Images were used to document and analyze closure …

Cochlear Implant Training Model, Devin Baughn, Sidney Mingle, Aaron Bowman

Williams Honors College, Honors Research Projects

Currently available training methods for cochlear implant surgeries such as cadavers and imaging systems are expensive and available for a limited number of training sessions. With the goal of decreasing risk factors associated with cochlear implant surgery, our team developed a cochlear implant training model prototype that is designed to provide a trial-and-error, tactile training method for developing force perception levels required to avoid causing damage to the cochlea. This model is designed to utilize a disposable material that ruptures when exposed to critical force levels. A material testing device was developed and utilized to test an assortment of easily …

Total Knee Arthroplasty Gap Balancer, Christina Grigorian, Andrew Beckley, Alexandra Rockett

Biomedical Engineering

California Polytechnic State University’s Biomedical Engineering Department worked in conjunction with local San Luis Obispo orthopedic surgeon Dr. Dimitri Delagrammaticas. The goal of the project was to create a surgical tool that assists a surgeon in measuring knee gap distance and balancing collateral ligament tension during a total knee arthroplasty (TKA) surgery. The final product of this project was completed in five months and initially began with understanding our sponsor’s expectations for the device. A portion of time was devoted to conducting research to understand the process of a knee replacement surgery, the requirements of the device, and the limitations …

Design And Development Of A Multifunctional Surgical Device For Ground And Space-Based Surgical Applications., Brooke Elaine Barrow

Electronic Theses and Dissertations

With the possibility of longer ventures into space, NASA will face many new medical challenges. The ability to surgically treat trauma and other disorders in reduced gravity requires reliable wound access, containment, and visualization. In collaboration with Carnegie Mellon University, the University of Louisville is currently developing the AISS (Aqueous Immersion Surgical System) to increase efficiency and control of the operative field in space-based surgeries. Reliable wound access and containment is achieved by placing a transparent wound-isolation dome securely over the wound-site and pressurizing it with a saline solution. Leak-free trocars provide access ports for various surgical instruments. This system …

Analysis Of Strain Transfer To Fbg’S For Sensorized Telerobotic End-Effector Applications, Dean Callaghan, Mark Mcgrath, Ginu Rajan, Eugene Coyle, Yuliya Semenova, Gerald Farrell

Books/Book chapters

Sensorized instruments which cater for the measurement of interaction forces during surgical procedures are not available on current commercial Minimally Invasive Robotic Surgical (MIRS) systems. This paper investigates the ef-fectiveness of advanced optical sensing technology (Fiber Bragg Grating) as sur-gical end effector strain/force sensors. The effects of adhesive bonding layer thickness and length are specifically addressed owing to their importance for ef-fective strain transfer and ensuring compactness of the resulting sensing arrange-ment. The strain transfer characteristics of the compound sensing arrangement are evaluated by the examination of shear transfer through the fiber coating and adhe-sive layers. Detailed analysis of the …

Force Measurement Methods In Telerobotic Surgery: Implications For End-Effector Manufacture, Dean Callaghan, Mark Mcgrath, Eugene Coyle

Articles

Haptic feedback in telesurgical applications refers to the relaying of position and force information from a remote surgical site to the surgeon in real-time during a surgical procedure. This feedback, coupled with visual information via microscopic cameras, has the potential to provide the surgeon with additional ‘feel’ for the manipulations being performed at the instrument-biological tissue interface. This increased sensitivity has many associated benefits which include, but are not limited to; minimal tissue damage, reduced recuperation periods, and less patient trauma. The inclusion of haptic feedback leads to reduction in surgeon fatigue which contributes to enhanced performance during operation. Commercially …

A Force Measurement Evaluation Tool For Telerobotic Cutting Applications: Development Of An Effective Characterization Platform, Dean Callaghan, Mark Mcgrath, Eugene Coyle

Articles

Sensorized instruments that accurately measure the interaction forces (between biological tissue and instrument endeffector) during surgical procedures offer surgeons a greater sense of immersion during minimally invasive robotic surgery. Although there is ongoing research into force measurement involving surgical graspers little corresponding effort has been carried out on the measurement of forces between scissor blades and tissue. This paper presents the design and development of a force measurement test apparatus, which will serve as a sensor characterization and evaluation platform. The primary aim of the experiments is to ascertain whether the system can differentiate between tissue samples with differing mechanical …