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Full-Text Articles in Biomechanics and Biotransport
Influence Of Obesity On Knee Joint Mechanics: A Subject-Specific Musculoskeletal Modeling Approach, Ryan C. Knowles
Influence Of Obesity On Knee Joint Mechanics: A Subject-Specific Musculoskeletal Modeling Approach, Ryan C. Knowles
Electronic Theses and Dissertations
Obesity has been consistently linked to knee osteoarthritis (KOA), a debilitating joint disease. While prior work has shown that obese individuals often walk with altered biomechanics compared to normal-weight (NW) individuals, which may accelerate KOA progression, less is known about how these mechanics affect load distribution between the medial and lateral tibiofemoral (TF) compartments, particularly during higher-demand activities. This study developed subject-specific musculoskeletal models of five obese and five NW individuals, incorporating CT-based bone measurements and individualized joint contact points. Simulations were driven by six degree-of-freedom (6DOF) kinematics obtained from high-speed stereo radiography (HSSR) to predict TF loading and associated …
Kinematic Analysis Of Gait And Deep Knee Flexion For Pre- And Post-Operative Total Knee Arthroplasty, Samantha Collins
Kinematic Analysis Of Gait And Deep Knee Flexion For Pre- And Post-Operative Total Knee Arthroplasty, Samantha Collins
Electronic Theses and Dissertations
Osteoarthritis (OA) is a form of arthritis that develops in the joint due to overuse and aging causing pain, discomfort, and disability. Total Knee Arthroplasty (TKA) is a surgical procedure performed when OA symptoms are severe with an estimated 600,000 patients in the United States currently receiving TKA. Studies have reported dissatisfaction of the knee for 14-39% of patients. This study collected knee kinematics before and after surgery using stereo radiography for precise measurement of gait and deep knee flexion activities. Results showed healthy knee kinematics were not restored and no significant changes could be seen from OA kinematics in …
Subject-Specific Human Knee Fea Models For Transtibial Amputees Vs Control Tibial Cartilage Pressure In Gait, Cycling And Elliptical Training, Ali Yazdkhasti
Subject-Specific Human Knee Fea Models For Transtibial Amputees Vs Control Tibial Cartilage Pressure In Gait, Cycling And Elliptical Training, Ali Yazdkhasti
Master's Theses
Millions of individuals around the globe are impacted by osteoarthritis, which is the prevailing type of arthritis. This condition arises as a result of gradual deterioration of the protective cartilage that safeguards the ends of the bones. This is especially true of transtibial amputees, who have a significantly higher incidence of osteoarthritis of the knee in their intact limb than non-amputees. Engaging in regular physical activity, managing weight effectively, and undergoing specific treatments can potentially slow down the advancement of the disease and enhance pain relief and joint function. Nevertheless, the relationship between the type of exercise and its impact …
Defining Sagittal Plane Gait Mechanics And Joint Loading In People With Marfan Syndrome, Justin Melan Pol
Defining Sagittal Plane Gait Mechanics And Joint Loading In People With Marfan Syndrome, Justin Melan Pol
Theses and Dissertations--Biomedical Engineering
Marfan syndrome (MFS) is a genetic condition that is associated with altered muscle composition, which leads to muscle dysfunction. People with MFS exhibit high instances of lower extremity (LE) joint pain that inhibits their ability to perform activities of daily living, such as walking. Despite these detrimental impacts of MFS, there have been no attempts to characterize the effects of MFS on LE joint loading and health during walking that are associated with LE pain and dysfunction. As people with MFS exhibit a high incidence rate of osteoarthritis (OA), the need to understand the potential alterations in LE extremity mechanics …
Development Of A Crosslinked Osteochondral Xenograft And A Collagen Stabilizing Intra-Articular Injection To Remediate Cartilage Focal Lesions To Prevent Osteoarthritis, Mark Lewis Mosher
Development Of A Crosslinked Osteochondral Xenograft And A Collagen Stabilizing Intra-Articular Injection To Remediate Cartilage Focal Lesions To Prevent Osteoarthritis, Mark Lewis Mosher
Theses and Dissertations
Osteoarthritis is one of the most common causes of disability in adults in America. It is a progressive and degenerative disease where the articular cartilage is broken down and lost from the surfaces of bones causing chronic pain and swelling in the joints, and currently has no cure. The most commonly osteoarthritis starts from a focal lesion on the cartilage surface, which will expand on the surface and downwards through the thickness of the tissue. The current gold standard for correcting cartilage focal lesions is the osteochondral autograft/allograft transplantation (OAT), which replaces the defect with a fresh osteochondral graft. The …
The Effect Of Implant Conformity On Muscle Force Requirements In The Implanted Knee, Grace Mcconnochie
The Effect Of Implant Conformity On Muscle Force Requirements In The Implanted Knee, Grace Mcconnochie
Boise State University Theses and Dissertations
Implant geometry is a significant factor in determining knee stability and patient satisfaction following total knee replacement (TKR). Ineffective muscle recruitment, impaired joint functionality and increased implant wear are consequences of an unstable knee replacement. Current knee laxity evaluation techniques are limited in their ability to account for the muscular response to knee instability. This study utilizes a subject specific lower-body musculoskeletal finite element (FE) model with dynamic muscle loading to evaluate implant laxity during activities of daily living. The effect of varying implant conformity on the muscle forces required to maintain a target kinematic profile during simulated laxity testing …
Development And Validation Of A Tibiofemoral Joint Finite Element Model And Subsequent Gait Analysis Of Intact Acl And Acl Deficient Individuals, Nicholas Czapla
Development And Validation Of A Tibiofemoral Joint Finite Element Model And Subsequent Gait Analysis Of Intact Acl And Acl Deficient Individuals, Nicholas Czapla
Master's Theses
Osteoarthritis (OA) is a degenerative condition of articular cartilage that affects more than 25 million people in the US. Joint injuries, like anterior cruciate ligament (ACL) tears, can lead to OA due to a change in articular cartilage loading. Gait analysis combined with knee joint finite element modeling (FEM) has been used to predict the articular cartilage loading. To predict the change of articular cartilage loading during gait due to various ACL injuries, a tibiofemoral FEM was developed from magnetic resonance images (MRIs) of a 33 year male, with no prior history of knee injuries. The FEM was validated for …
Finite Element Analysis And Validation Of Hip Joints With The Main Types Of Femoroacetabular Impingement, Kevin Lucas Mitchell
Finite Element Analysis And Validation Of Hip Joints With The Main Types Of Femoroacetabular Impingement, Kevin Lucas Mitchell
Master's Theses
Current research suggests that femoroacetabular impingement can be a cause of osteoarthritis. Femoroacetabular impingement is a condition that can affect both the femur and the pelvis of an individual. Femoroacetabular impingement can cause damage to the hip joint and its surrounding tissues. The articular cartilage and the labrum are both affected by this condition. A cam impingement is where a bony protrusion develops at the femoral head/neck junction. A pincer impingement is where a bony protrusion develops at the acetabular rim. Often, patients are seen with a combination of both impingements. The main goal of this study was to computationally …