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Biomechanics and Biotransport Commons™
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Articles 1 - 8 of 8
Full-Text Articles in Biomechanics and Biotransport
Investigating Endothelial Damage During Ischemic Stroke Treatment Using In Vitro And Computational Models, Zackary Lorton
Investigating Endothelial Damage During Ischemic Stroke Treatment Using In Vitro And Computational Models, Zackary Lorton
Theses and Dissertations
Large vessel occlusion during acute ischemic strokes requires mechanical thrombectomy (MT) procedures using stent retrievers (SR). However, complete clot removal typically takes several attempts, which can amplify endothelial cell injury (EI). This project aims to characterize the extent of EI during MT using an in vitro vascular platform and a finite-element model (FEM). Impact of SR diameter and characterization of SR mechanical forces are assessed and correlated with human umbilical vein endothelial cell (HUVEC) response. HUVECs were seeded on fibronectin (4 µg/cm2) coated true-scale PDMS arterial phantoms with 2.5 mm luminal diameter. Test groups (n=6) either …
In Vivo Data Capture Using Hssr For Calibration Of Computational Models, Thor Erik Andreassen
In Vivo Data Capture Using Hssr For Calibration Of Computational Models, Thor Erik Andreassen
Electronic Theses and Dissertations
Computational modeling is a vital tool for understanding and evaluating healthy and unhealthy function of the musculoskeletal aspects of the human body. However, the accuracy of the musculoskeletal models depends significantly on the accuracy of the input data used to calibrate various behavioral parameters of the model. To date, most computational models have been built using generic in vitro data, mostly because of a lack of accurate and meaningful datasets from in vivo testing. The next major step in computational modeling is to create subject-specific computational models using calibration data taken from in vivo testing. The overall goal was to …
Du02, Center For Orthopaedic Biomechanics, Michael D. Harris, Phd, Kevin Shelburne, Phd
Du02, Center For Orthopaedic Biomechanics, Michael D. Harris, Phd, Kevin Shelburne, Phd
Natural Knee Data
No abstract provided.
Du06, Center For Orthopaedic Biomechanics, Michael D. Harris, Phd, Kevin Shelburne, Phd
Du06, Center For Orthopaedic Biomechanics, Michael D. Harris, Phd, Kevin Shelburne, Phd
Natural Knee Data
No abstract provided.
Du05, Center For Orthopaedic Biomechanics, Michael D. Harris, Phd, Kevin Shelburne, Phd
Du05, Center For Orthopaedic Biomechanics, Michael D. Harris, Phd, Kevin Shelburne, Phd
Natural Knee Data
No abstract provided.
Du04, Center For Orthopaedic Biomechanics, Michael D. Harris, Phd, Kevin Shelburne, Phd
Du04, Center For Orthopaedic Biomechanics, Michael D. Harris, Phd, Kevin Shelburne, Phd
Natural Knee Data
No abstract provided.
Du03, Center For Orthopaedic Biomechanics, Michael D. Harris, Phd, Kevin Shelburne, Phd
Du03, Center For Orthopaedic Biomechanics, Michael D. Harris, Phd, Kevin Shelburne, Phd
Natural Knee Data
No abstract provided.
Du01, Center For Orthopaedic Biomechanics, Michael D. Harris, Phd, Kevin Shelburne, Phd
Du01, Center For Orthopaedic Biomechanics, Michael D. Harris, Phd, Kevin Shelburne, Phd
Natural Knee Data
No abstract provided.