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Articles 31 - 49 of 49
Full-Text Articles in Biomaterials
Impact Of Glass Powder As A Sustainable Material On The Workability, Strength, And Durability Properties In High-Performance Basalt Fiber Reinforced Concrete: A Statistical Analysis, Ahmed Fathi Mohamed Salih
Impact Of Glass Powder As A Sustainable Material On The Workability, Strength, And Durability Properties In High-Performance Basalt Fiber Reinforced Concrete: A Statistical Analysis, Ahmed Fathi Mohamed Salih
Journal of Sustainable Construction Materials and Technologies
The global construction sector is increasingly challenged to balance environmental sustainability with the growing demand for durable, high-performance materials. As cement production continues to be a major source of anthropogenic CO2 emissions, the incorporation of alternative, low-impact binders has become a key strategy for reducing the environmental footprint of concrete. In this context, glass powder (GP)—a finely ground industrial by-product rich in amorphous silica—has emerged as a promising partial replacement for Portland cement. Its pozzolanic reactivity contributes to improved hydration and matrix densification, while its use also supports circular economy principles by diverting waste glass from landfills. At the same …
Balancing Carbon Emissions In Façade Of Residential Buildings Through Bim-Lca: A Comparative Analysis Of Insulation Materials, Mehran Alipour
Balancing Carbon Emissions In Façade Of Residential Buildings Through Bim-Lca: A Comparative Analysis Of Insulation Materials, Mehran Alipour
Journal of Sustainable Construction Materials and Technologies
Thermal insulation materials play a significant role in balancing buildings' total carbon emissions. Balancing involves applying the optimized amount of insulation materials to avoid excessive emissions in either the operational or embodied phases. Due to the wide range of insulation materials and variations of their specifications, it is vital to analyse them individually. The focus of this study is to optimize the amount of insulation materials in the facades of Residential Buildings (RB) to balance the amount of Operational Carbon Emissions (OCE) and Embodied Carbon Emissions (ECE) by applying the Building Information Modelling-Life Cycle Assessment (BIM-LCA) integration method. The Life …
Integrating Sustainable Material Procurement In Construction Waste Management: A Systematic Review With Narrative Synthesis For The Libyan Construction Sector, Ramzi Fouzi Hamad Abdullah, Safaa N Saud Al-Humairi, Zunirah Binti Mohd Talib
Integrating Sustainable Material Procurement In Construction Waste Management: A Systematic Review With Narrative Synthesis For The Libyan Construction Sector, Ramzi Fouzi Hamad Abdullah, Safaa N Saud Al-Humairi, Zunirah Binti Mohd Talib
Journal of Sustainable Construction Materials and Technologies
Integrating sustainable material procurement with construction waste management is essential to reduce construction and demolition waste in Libya, where current practices remain largely reactive and disposal-oriented. This narrative review aims to develop a conceptual framework linking procurement decisions to waste-generation pathways in Libyan construction projects, clarifying how proactive, sustainability-driven purchasing can serve as a primary driver of waste prevention. Using a PRISMA-guided systematic search of Web of Science, Scopus, and IEEE Xplore for 2001–2026, and a bibliometric analysis via VOSviewer, 956 high-quality studies were synthesized to map global knowledge and to expose the paucity of integrated SMP–CWM studies in developing …
Sound Insulation Performance Of Sustainable Lc3 Mortars With Barite And Waste Rubber Aggregates, Begüm Söyek Abay, Leyla Tanaçan
Sound Insulation Performance Of Sustainable Lc3 Mortars With Barite And Waste Rubber Aggregates, Begüm Söyek Abay, Leyla Tanaçan
Journal of Sustainable Construction Materials and Technologies
This study investigates the potential of limestone calcined clay cement (LC3) as a sustainable binder for developing a single-layer composite material incorporating barite and rubber aggregates, hypothesized to achieve enhanced sound insulation performance compared to conventional multi-layered wall systems. Mortars were prepared using LC3 with 55% clinker, 30% metakaolin, 15% limestone, substituting 45% of cement clinker. Hybrid mixtures of barite and rubber aggregates (barite-to-rubber volume ratios of 2:1 and 1:2) were tested at aggregate-to-binder ratios of 2.0, 2.75, and 3.5 to evaluate their combined mass and damping effects on acoustic performance. Experiments were conducted to determine physical, mechanical, and acoustic …
From Lime To Geopolymers: Emerging Trends And Advances In Sustainable Soil Stabilization, Favour Chukwuebuka Egwu, Amin Eisazadeh
From Lime To Geopolymers: Emerging Trends And Advances In Sustainable Soil Stabilization, Favour Chukwuebuka Egwu, Amin Eisazadeh
Journal of Sustainable Construction Materials and Technologies
Soil stabilization remains a critical challenge in geotechnical engineering, particularly for weak and expansive soils that compromise the safety and serviceability of infrastructure. Traditional stabilizers such as lime and cement have been widely applied; however, their limitations in terms of long-term durability, carbon footprint, and performance under aggressive environmental conditions necessitate alternative approaches. In recent years, geopolymer-based stabilizers derived from industrial by-products such as fly ash (FA), slag, and bottom ash (BA) have emerged as promising substitutes. This review critically examines the comparative performance of lime and geopolymer stabilization with respect to strength development, durability, compressibility, environmental impact, and economic …
Investigating The Behavior Of Self-Compacting Concrete Containing Scms And Recycled Fine Aggregates, Sachin Tiwari, Mahakavi P
Investigating The Behavior Of Self-Compacting Concrete Containing Scms And Recycled Fine Aggregates, Sachin Tiwari, Mahakavi P
Journal of Sustainable Construction Materials and Technologies
This study addresses the unresolved gap in quantifying how recycled fine aggregates (RFA) and metakaolin (MK) interact synergistically in self-compacting concrete (SCC), a relationship that previous works have studied only in isolation or without mechanistic justification. Twenty-five SCC mixtures containing MK (0–25%) and RFA (0–100%) were evaluated to generate a unified understanding of fresh behaviour, strength development, pore refinement, interfacial transition zone (ITZ) characteristics, and sustainability indicators. Results show that RFA alone increases water demand and reduces strength, while MK compensates for these losses by densifying the matrix and improving ITZ bonding, as confirmed through SEM analysis. An optimum synergy …
Tetramethylbenzidine Loaded Pva Nanofibers Strip For Visual Detection Of Hydrogen Peroxide Via Cu2+ Catalysis And Its Applications, Samar A. Salim
Tetramethylbenzidine Loaded Pva Nanofibers Strip For Visual Detection Of Hydrogen Peroxide Via Cu2+ Catalysis And Its Applications, Samar A. Salim
Nanotechnology Research Centre
Background Advancements in sensor technology have facilitated the development of cost-effective and highly sensitive sensors which have significantly improved the detection of biological analytes in various fields. This study presents a novel approach for the detection of hydrogen peroxide (H₂O₂), a critical analyte in both biological and environmental systems. A simple and sensitive colorimetric sensing platform was developed based on polyvinyl alcohol (PVA) nanofibers loaded with tetramethylbenzidine (TMB). Results The nanofibers were characterized using scanning electron microscopy, confirming the formation of smooth, spindle-shaped fibers with diameters from 324 to 551 nm. The colorimetric detection method utilized TMB, which undergoes oxidation …
Photocrosslinkable Morin-Loaded Gelatin-G-Gma Composite Hydrogel For Accelerating Burn Wound Healing: In Vitro And In Vivo Assessments, Samar A. Salim
Photocrosslinkable Morin-Loaded Gelatin-G-Gma Composite Hydrogel For Accelerating Burn Wound Healing: In Vitro And In Vivo Assessments, Samar A. Salim
Nanotechnology Research Centre
The impaired skin regeneration, scarring, and delayed healing make the management of burn injuries a challenging task. We designed a photopolymerized hydrogel of gelatin-grafted with glycidyl methacrylate (GMA) for burn management applications. Hydrogel was incorporated with Morin, a plant flavonoid that was originally isolated from the Moraceae family, with known anti-antioxidant and antifibrotic activities. The physicochemical characterization of the resultant hydrogel, including its gelation time and swelling properties, was conducted. The characterization results indicated that the hydrogel development was successful, exhibiting well-established porosity, as evidenced by the SEM images. In vivo evaluation demonstrated improved tissue regeneration characterized by enhanced collagen …
Volumetric Wear Analysis Of Polyethylene Orthopedic Liners Using Point Clouds, Gabriel Landi
Volumetric Wear Analysis Of Polyethylene Orthopedic Liners Using Point Clouds, Gabriel Landi
Dartmouth College Master’s Theses
In vivo wear of ultra-high molecular weight polyethylene (UHMWPE) orthopedic bearings represents a major problem in shoulder and knee arthroplasty, with significant amounts of devices failing due to the complication itself, and even more due to associated reasons for retrieval, including aseptic loosening. However, quantification of UHMWPE wear has largely been limited to linear and in vitro volumetric analyses, obscuring the understanding of the amount of clinically relevant material loss. This study proposes new methods to measure articular, rim, and backside surfaces of retrieved shoulder and knee UHMWPE liners, centered around the coordinate measuring machine (CMM)-based collection of high density …
Enhancing Wound Healing With Synergistic Dual-Drug Electrospun Roflumilast And L-Arginine Loaded Pla/Pva Nanofibers Through Fabrication, Optimization, And In Vivo Assessment, Samar A. Salim
Nanotechnology Research Centre
Current trends in improved wound management emphasize the development of dual-drug-loaded electrospun nanofibrous scaffolds. Herein, electrospun dual-drug loaded PLA/PVA nanofibrous scaffolds, incorporating roflumilast, a selective phosphodiesterase-4 inhibitor with anti-inflammatory activity, and L-arginine, a precursor to nitric oxide with stimulating activity towards wound healing and tissue regeneration, were developed. A dual-spinneret electrospinning process enabled the coloading of drugs in PLA and PVA phases. Scaffolds were characterized by SEM, FTIR, and XRD, showing consistent fiber morphology, and amorphous drug formation. FTIR analysis was performed to confirm drug–polymer compatibility and successful incorporation of roflumilast and L-arginine within the PLA/ PVA nanofibrous matrix. Swelling …
Bioprinted Scaffolds For Investigating Fibroblast Alignment, Lillian Thro, Daeha Joung Ph.D.
Bioprinted Scaffolds For Investigating Fibroblast Alignment, Lillian Thro, Daeha Joung Ph.D.
UROP Posters
Fibroblasts play a vital role in tissue repair, ECM remodeling, and maintaining structural integrity in human tissues. However, their behavior in engineered 3D microenvironments remains poorly understood. Traditional 2D cultures fail to capture the complex cell-cell and cell-matrix interactions that govern fibroblast alignment, migration, and proliferation in vivo. To address this gap, this project uses bioprinted scaffolds that mimic native ECM structures and provide a platform for studying fibroblast behavior in controlled microenvironments. The project focuses on varying scaffold channel properties—such as width, depth, and geometry—to investigate how physical cues influence fibroblast organization and collective migration. A biodegradable gelatin-based ECM …
Synthesis And Characterization Of Glass-Ceramic Nanoparticles And Nanobubbles For Integration Into Bone Regenerative Biomaterials, Sun Latt
Honors Undergraduate Theses
Osteoporosis affects over 200 million individuals worldwide and is characterized by an imbalance between osteoclastic bone resorption and osteoblastic bone formation, leading to fragility fractures that significantly diminish quality of life. Current clinical bone cements, such as poly(methyl methacrylate), are limited by poor osseointegration, toxic monomers, and an inability to address the underlying pathophysiology of osteoporosis. This work presents the synthesis, characterization, and systematic in vitro evaluation of a sol-gel-derived, magnesium-incorporated glass-ceramic (GC) nanoparticle within the CaO-MgO-SiO2 system for incorporation into a novel hydrogel bone cement and bioresorbable magnesium implants. XRD confirmed a biphasic amorphous-crystalline diopside composition, and TEM …
De Novo Protein Binding To Zinc Oxide Through Biomineralization Pathways, Jean-Mark A. Francis
De Novo Protein Binding To Zinc Oxide Through Biomineralization Pathways, Jean-Mark A. Francis
Theses and Dissertations
De novo proteins are structurally distinct from proteins found in nature and thus capable of having their amino acid sequence modified to accomplish tasks such as increasing protein-nanoparticle binding without unfolding or decomposing. Zinc Oxide nanoparticles are functionally distinct from their bulk counterparts and are widely used as semiconductors in a variety of fields such as medicine and agriculture. With demand for these nanoparticles increasing, environmentally sustainable methods of Zinc Oxide nanoparticle synthesis are being investigated as an eco-friendly alternative to currently utilized but environmentally hazardous chemical and physical techniques. This research investigates the binding characteristics between Zinc Oxide nanoparticles …
Development Of An Adhesive Emulsion Hydrogel For Soft Tissue Reconstruction, David J. Alpert
Development Of An Adhesive Emulsion Hydrogel For Soft Tissue Reconstruction, David J. Alpert
Dissertations and Theses
Soft tissue filling materials are most commonly associated with various aesthetic, cosmetic procedures, primarily using lightly cross-linked hyaluronic acid to fill wrinkles and give facial features a more youthful appearance. These natural materials are biocompatible but degrade over time while more persistent synthetic fillers may provoke a chronic inflammatory response. Migration from the injection site is also a key factor as this may not only render the implant non- functional but necessitate further procedures for removal of the foreign material. Such concerns are more pronounced for soft tissue reconstruction procedures (e.g., to treat congenital defects or traumatic injuries), which require …
Engineering Plga Nanoparticle Size To Modulate Immune Responses After Spinal Cord Injury, Daniel J. Kolpek
Engineering Plga Nanoparticle Size To Modulate Immune Responses After Spinal Cord Injury, Daniel J. Kolpek
University of Kentucky Doctoral Dissertations
Spinal cord injury is a severe and debilitating condition that often results in lifelong complications, including paralysis. Many of these chronic outcomes are driven by a sustained inflammatory response at the injury site, which limits tissue regeneration and functional recovery. As a result, therapeutic strategies that modulate this immune response have gained significant interest. Polymer based nanoparticle therapies have emerged as a promising approach due to their ability to interact with and influence immune cell behavior. Importantly, the physicochemical properties of nanoparticles can be precisely tuned to optimize these effects. Among these properties, size has been shown to influence key …
Generating Concentrated Ring Polymers Through Supercoiled And Open Circle Pdna Isoform Separation, Kelsey E. Hodsdon
Generating Concentrated Ring Polymers Through Supercoiled And Open Circle Pdna Isoform Separation, Kelsey E. Hodsdon
Honors Theses and Capstones
DNA can serve as a model polymer due to its high uniformity compared to synthetic polymers. Plasmid DNA (pDNA) in particular offers a well-defined, low-dispersity model for studying topologically uniform systems of a cyclic nature. pDNA has unique isoforms known as open circle (OC) and supercoiled (SC). Using fast protein liquid chromatography (FPLC), specifically anion exchange chromatography (AEX), these OC and SC isoforms can be separated in order to access their unique material properties. Our lab was able to yield the pure SC isoform. However, OC isoform separation has been more challenging. Various difficulties arose during this process, including imaging …
Stentrx, Emma Barna, Minuthi Cooray, Bruce Newlands, Joseph A. Sabetta
Stentrx, Emma Barna, Minuthi Cooray, Bruce Newlands, Joseph A. Sabetta
Williams Honors College, Honors Research Projects
This project aims to develop a biodegradable, drug-eluting biliary stent for the treatment of biliary cancers. Current metal stents that restore bile flow bit are non-degradable, prone to migration, and unable to deliver drugs locally. The proposed stent will be biocompatible, biodegradable, and capable of controlled drug release to both maintain bile flow and treat tumors. The end goal is to produce a functional prototype that can be deployed via a minimally invasive catheter and maintain bile duct patency for at least three months. The project is expected to be involved in the NEOMED Bench-to-Bedside competition and provisionally patented.
Recent Advances In Bioceramics, Fundamental Properties And Future Perspective In Biomedical Applications ‒ A Review, Ayesha Younas, Muhammad Umar Aslam Khan, Mohd Faizal Binte Abdullah, Lobat Tayebi, Shuanghu Wang, Abdalla Abdal-Hay, Yichi Xu
Recent Advances In Bioceramics, Fundamental Properties And Future Perspective In Biomedical Applications ‒ A Review, Ayesha Younas, Muhammad Umar Aslam Khan, Mohd Faizal Binte Abdullah, Lobat Tayebi, Shuanghu Wang, Abdalla Abdal-Hay, Yichi Xu
Electrical & Computer Engineering Faculty Publications
Bioceramics are important biomaterials in biomedical engineering because of their biocompatibility, bioactivity, osteoconductivity, and structural resemblance to actual bone tissue. In recent years, materials science and nanotechnology have enabled the use of bioceramics in bone regeneration, dental restoration, tissue engineering, drug delivery systems, and implantable medical devices. This comprehensive review covers advances in bioceramics, including calcium phosphates, hydroxyapatite (HAp), tricalcium phosphate, bioactive glasses, zirconia, alumina, and multifunctional ceramic nanocomposites. Priority is given to techniques such as additive manufacturing, 3D printing, sol-gel processing, electrospinning, and nanostructuring to improve mechanical strength, porosity, bioactivity, and cell interactions. Recent advances include ion doping, surface …
Parametric Study Of Yields And Properties Of Corn Stover-Derived Hydrothermal Liquefaction Products By Using Statistical Approaches, Isamu Umeda, Meicen Liu, Jiefu Wang, Yi Zheng, Zhiwu Wang, Jaya Shankar Tumuluru, Sandeep Kumar
Parametric Study Of Yields And Properties Of Corn Stover-Derived Hydrothermal Liquefaction Products By Using Statistical Approaches, Isamu Umeda, Meicen Liu, Jiefu Wang, Yi Zheng, Zhiwu Wang, Jaya Shankar Tumuluru, Sandeep Kumar
Civil & Environmental Engineering Faculty Publications
Hydrothermal liquefaction (HTL) of lignocellulosic biomass produces multiple product fractions, including solid residue (SR), heavy bio-oil (HBO), aqueous phase (AP), and light bio-oil (LBO). This study mainly applied principal component analysis (PCA) and regression modeling to predict AP solution weight, LBO weight and fuel characteristics, and HTL wastewater biodegradability, as well as to improve prediction accuracy for SR and HBO under various operating conditions (temperature: 250–350 °C, residence time: 5–60 min, and the combined solid loading of three batches: 15–45 g). A complementary relationship between SR and AP weights found in PCA enabled the estimation of AP weight based on …