Open Access. Powered by Scholars. Published by Universities.®
Biomedical Engineering and Bioengineering Commons™
Open Access. Powered by Scholars. Published by Universities.®
- Discipline
- Keyword
-
- EEG (4)
- Electroencephalography (3)
- FNIRS (3)
- Functional connectivity (3)
- Calcitriol (2)
-
- Cognitive function (2)
- Microchannel (2)
- Near-Infrared Spectroscopy (2)
- Obstructive sleep apnea (2)
- Photobiomodulation (2)
- Prostate cancer (2)
- Sleep apnea (2)
- 3D Printing (1)
- Actin (1)
- Adipocyte (1)
- African Americans (1)
- Alpha band (1)
- Antibodies (1)
- Apnea duration (1)
- Bacterial cellulose (1)
- Biomechanics (1)
- Biophotonics (1)
- Blood flow (1)
- Blood pressure variation (1)
- Brain network (1)
- Breath-hold MRI scan (1)
- Broadband near-infrared Spectroscopy (1)
- CCO (1)
- CVD (1)
- Cancer detection (1)
- Publication Year
- File Type
Articles 31 - 60 of 194
Full-Text Articles in Biomedical Engineering and Bioengineering
Interactive Analytical Tool For Quantitative Corneal Confocal Imaging In Vivo, Madhavi Tippani
Interactive Analytical Tool For Quantitative Corneal Confocal Imaging In Vivo, Madhavi Tippani
Bioengineering Theses - Archive
The objective of this study was to develop an interactive software application for image reconstruction and analysis of the corneal data from an in vivo confocal microscope (Heidelberg Retinal Tomograph with Rostock Corneal Module, HRT-RCM). The optical sectioning ability of confocal microscopy gives high resolution optical section images at different depths within a thick tissue, thereby eliminating the need for physical sectioning. This ability of 4-dimensional (x,y,z and t) imaging makes confocal microscopy uniquely suited for imaging the cornea at the cellular level. The new program was developed to overcome the drawbacks of the original application “Confo” developed in the …
Investigation Of Prefrontal Cognition Responses To Transcranial Laser Stimulation In Ptsd Using Functional Near Infrared Spectroscopy, Dev Rajanikant Patel
Investigation Of Prefrontal Cognition Responses To Transcranial Laser Stimulation In Ptsd Using Functional Near Infrared Spectroscopy, Dev Rajanikant Patel
Bioengineering Theses - Archive
In recent years low level laser therapy (LLLT) has been of great research interest because of its therapeutic applications in psychiatry, neurology and ophthalmology. In-vivo transcranial delivery of LLLT has shown to induce beneficial metabolic effects and increase in cognitive functions and hence has been found to be useful in treating neurodegenerative disorders. The aim of this study was to evaluate effects of LLLT on prefrontal cognitive functions, namely attention and short term memory, over six sessions on veterans with Post-Traumatic Stress Disorder (PTSD), using near infrared spectroscopy (fNIRS). In this study the subjects were instructed to perform two neurocognitive …
Diffused Correlation Spectroscopy For Measurement Of Blood Perfusion During Low Level Laser Therapy (Lllt), Soni Sagar
Diffused Correlation Spectroscopy For Measurement Of Blood Perfusion During Low Level Laser Therapy (Lllt), Soni Sagar
Bioengineering Theses - Archive
Near infrared stimulation or Low Level Laser Therapy (LLLT) is an innovative technique shown to effect the microvasculature hemodynamics. The aim of this study is to use Diffused Correlation Spectroscopy (DCS) to evaluate the physiological effects of LLLT on blood perfusion. This study is divided into two parts: the fist part is the development of DCS system and the second part is investigating the effects of LLLT on biological tissue. DCS is an emerging non-invasive technique to probe deep tissue hemodynamics. DCS uses time-averaged intensity autocorrelation function for the fluctuations caused due to the moving scatterers (RBCs) in biological tissue. …
Manipulating The K-Space For Reduction Of Respiratory Induced Motion Artifacts, Maida Ranjbar
Manipulating The K-Space For Reduction Of Respiratory Induced Motion Artifacts, Maida Ranjbar
Bioengineering Theses - Archive
Respiratory induced motion artifacts, particularly those occurring in the abdomen and lung, pose a hefty problem in current diagnostic MR imaging. Application of images plagued with such artifacts not only hinder diagnosis, but may result in the enforcement of undesirably large safety margins in radiation therapy due to un-captured tumor characteristics that are concealed by the artifact. While several methods such as gated scans, breath-hold scans, variation of the K-Space acquisition trajectory, and reducing the scan time via partial acquisition or parallel imaging have been proposed as a solution, a robust and yet simple to implement remedy still remains to …
An Investigation Of The Relation Between Sleep Disordered Breathing And Cognitive Function, Nazaneen Mousavi
An Investigation Of The Relation Between Sleep Disordered Breathing And Cognitive Function, Nazaneen Mousavi
Bioengineering Theses - Archive
Obstructive sleep apnea (OSA) is one of the most prevalent sleep related breathing disorders, with an estimated amount 17% of affected adults in the U.S. Research has linked OSA to mood and cognitive disorders, including Alzheimer’s disease. Structural changes in the brain have also been found to be associated with OSA. Several studies have shown deterioration of cognition in OSA patients because of structural and physiological changes due to apnea. The purpose of this research is to study the correlational relationships between cognitive measures and 1) quantitative measures of sleep quality; 2) measures of sleep disordered breathing; and 3) hypoxia …
Hemodynamic Responses To Thermal Stimulation In The Prefrontal Cortex Of The Brain Measured By Fnirs, Koumudi Chari
Hemodynamic Responses To Thermal Stimulation In The Prefrontal Cortex Of The Brain Measured By Fnirs, Koumudi Chari
Bioengineering Theses - Archive
Although FMRI has marked its importance in the neurological research by understanding the brain activities, FNIRS has also set a new standard in the brain imaging study research with non-invasive and easy to use technology. FNIRS is a portable, inexpensive optical imaging method that measures the changes in the oxygenated and de-oxygenated hemoglobin of the brain that results from the neurological activity. In this study, FNIRS has been used to study the pain processing in humans by measuring the pre-frontal cortex area of the brain. Eight (n=8) healthy subjects were induced with pain using a thermal stimulator device with temperatures …
An Investigation Of The Covariations Between Variations In Exhaled Carbon Dioxide And Cerebral Blood Flow Levels During Apnea, Varun Ajay Kanal
An Investigation Of The Covariations Between Variations In Exhaled Carbon Dioxide And Cerebral Blood Flow Levels During Apnea, Varun Ajay Kanal
Bioengineering Theses - Archive
Sleep apnea is a breathing disorder characterized by repetitive reduction or cessation of breathing during sleep. It is estimated that that around 17% of adults suffer from mild to severe sleep disordered breathing. The aim of this study was to investigate the level of correlation between variations in exhaled CO2 and cerebral blood flow (CBF) during apnea. It is difficult to measure the CBF during sleep. This relationship was found in an effort to substitute the measurement of the changes in CBF with the changes in the CO2. The relationship between these two physiological parameters was first studied in healthy …
Transcranial Near Infrared Spectroscopy And Stimulation Of Prefrontal Cognitive Functions In Young Adults, Snehal Niwrutti Hase
Transcranial Near Infrared Spectroscopy And Stimulation Of Prefrontal Cognitive Functions In Young Adults, Snehal Niwrutti Hase
Bioengineering Theses - Archive
Transcranial near infrared stimulation or Low Level Laser Therapy (LLLT) is an innovative technique shown to control neuronal function in cell cultures, animal models and clinical conditions. The aim of this study was to use near infrared spectroscopy (NIRS) to evaluate the physiological and functional effects of LLLT on prefrontal cognitive functions in young healthy adults. This study was divided into two parts: the first part investigated the physiological effects of LLLT and the second investigated the functional effects.The aim of the first part of this study was to explore how a single session of LLLT altered the hemodynamic status …
Measurement Of Cerebral Blood Flow Using Arterial Spin Labeling Method Across Lifespan, Ciwen Wang
Measurement Of Cerebral Blood Flow Using Arterial Spin Labeling Method Across Lifespan, Ciwen Wang
Bioengineering Theses - Archive
Arterial Spin Labeling (ASL) is one family of perfusion-weighted contrast imaging techniques of Magnetic Resonance Imaging (MRI) that measures cerebral blood flow by labeling spins in arterial blood with inversion and then waiting for a certain period of time for the labeled arterial blood to enter the imaging plane, and then acquiring MR image at the image plane. In compare with PET, ASL is a noninvasive new technology. But as a new technology, it is not very commonly used because of the relatively low signal to noise ratio, less robust mechanism, and more important, there is no standard for clinical …
Decreased Expression Of Microtubules In Confined Microenvironments Leads To A Reduced Effect Of Paclitaxel On Breast Cancer Cells, Bailey Sayles
Decreased Expression Of Microtubules In Confined Microenvironments Leads To A Reduced Effect Of Paclitaxel On Breast Cancer Cells, Bailey Sayles
Bioengineering Theses - Archive
Despite the current medical options available to patients, cancer cells frequently remain after treatment and metastasize. This is particularly significant because secondary cancers account for 90% of cancer-related fatalities. Using standard lithography techniques to make PDMS-based microchannel devices, different microenvironments for studying metastasizing (MDA-MB-231) and non-metastasizing (MCF-7) breast cancer cells were created. While the cells were in the narrow and wide microchannels, effects of the anti-cancer drug Paclitaxel at different concentrations were examined and compared with the traditional Transwell assay. Paclitaxel stabilizes microtubules inside the cell and restricts replication, making it an ideal drug to target for quickly dividing cancer …
A Glm/Ica Analysis Using Motion Tracking And Electromyography Differentiates Between Brain Activation Due To Intended And Unintended Motions In Fnirs Images Acquired During A Finger Tapping Task Performed By Children With Cerebral Palsy, Nathan Hervey
Bioengineering Theses - Archive
Functional neurological imaging has been shown to be valuable in evaluating brain plasticity in children with cerebral palsy (CP). In recent studies it has been demonstrated that functional near-infrared spectroscopy (fNIRS) is a viable and sensitive method for imaging motor cortex activities in children with CP. However, during unilateral finger tapping tasks children with CP often exhibit mirror motions (unintended motions in the non-tapping hand), and current fNIRS image formation techniques do not account for these motions. Therefore, the resulting fNIRS images contain activation from both intended and unintended motions. In this study, cortical activity was mapped with fNIRS on …
Computational Modeling Of Drug Release From Nerve Guide Conduit Of Different Designs, Lokesh Shamkant Patil
Computational Modeling Of Drug Release From Nerve Guide Conduit Of Different Designs, Lokesh Shamkant Patil
Bioengineering Theses - Archive
Currently there are limited effective strategies and surgical methods for repairing gap peripheral nerve injuries. Autografts are commonly used but with major limitation in the availability of donor graft material and the painful sensations at donor site. These limitations call for the development of new, effective methods for repairing peripheral nerve injuries. The use of nerve guide conduits to facilitate nerve growth and repair have shown promising potential with minimum side-effects but still with limited success in a full functional recovery. The likely clinical outcome could benefit significantly with the use of engineering methodologies in the design, fabrication, surgical delivery …
Cross Wavelet Analysis Of Cerebral Hemodynamics In Young And Older Adults, Mrunmayee Sunil Gandhi
Cross Wavelet Analysis Of Cerebral Hemodynamics In Young And Older Adults, Mrunmayee Sunil Gandhi
Bioengineering Theses - Archive
Measurement of cerebral autoregulation is important for the evaluation of a number of clinical disorders that affect cerebral blood flow. Cerebral autoregulation is a mechanism that involves dilation and constriction in arterioles to maintain relatively stable cerebral blood flow in response to changes of systemic blood pressure. Traditional assessments of autoregulation focus on the changes of cerebral blood flow velocity in response to large blood pressure fluctuations induced by interventions. This approach is not feasible for patients with impaired autoregulation or cardiovascular regulation. Therefore in this thesis, a non-stationary time-frequency analysis method, Cross Wavelet Transform is used, which assess autoregulation …
Simulation Feasibility Studies Of A High Density Fnirs Imaging System, Pallavi Natekar
Simulation Feasibility Studies Of A High Density Fnirs Imaging System, Pallavi Natekar
Bioengineering Theses - Archive
Functional near infrared spectroscopy (fNIRS) is a technique that enables monitoring brain function, by detecting changes in near-infrared light absorbance resulting from changes in brain hemodynamics during periods of rest and activation. Although the technique has some advantages over other conventional functional imaging methods with its inherently high temporal sampling and detection sensitivity, the sparse spatial sampling of current fNIRS systems limits spatial resolution and requires help from Magnetic Resonance Imaging (MRI) to attain spatial co-registration with anatomical structures. In this work we have performed simulations to test the feasibility of using a high density spatial sampling system as a …
Performance Of Wavelet Denoising And Automatic Detection Of Action Potentials On Simulated And Real Electrneurographic Recordings, Manikandan Ravi
Performance Of Wavelet Denoising And Automatic Detection Of Action Potentials On Simulated And Real Electrneurographic Recordings, Manikandan Ravi
Bioengineering Theses - Archive
About 1 in 200 people living in the U.S have had an amputation at some stage in their lives. Development of neurally controlled artificial limb prosthesis with the ability to finely control motor activity continues to prove difficult for researchers in the field. One approach is to use the signals obtained from the peripheral nerves by placing an intraneural electrode in the nerve. Since this signal is very noisy, much of the useful information is either lost or buried in the noise even after FIR filtering. Furthermore, there is a need for fast, automated detection of action potentials in order …
An Investigation Of Concurrent Variations In Blood Oxygen Saturation And Cerebral Blood Flow During Apnea, Jennifer Swittens
An Investigation Of Concurrent Variations In Blood Oxygen Saturation And Cerebral Blood Flow During Apnea, Jennifer Swittens
Bioengineering Theses - Archive
Sleep apnea derived from Greek word "apnoia" which means "without air or temporary interruption in breathing", is a sleep - associated breathing disorder that involves a decrease or complete stop in airflow despite a constant effort to breathe. It is estimated that sleep apnea is prevalent in the US in 18 million people and is approximately 6% of the population.This thesis aims to study the physiological effects of sleep apnea on cerebral blood flow (CBF) and the percentage oxygen saturation (%SaO2), the effect of duration of apnea episode or a breath hold on CBF and %SaO2 and to derive a …
Noninvasive Assessment Of Tumor Hypoxia Using Oxygen Sensitive Mri In Prostate Tumor Models, Rashmi Reddy Pabhathi Reddy
Noninvasive Assessment Of Tumor Hypoxia Using Oxygen Sensitive Mri In Prostate Tumor Models, Rashmi Reddy Pabhathi Reddy
Bioengineering Theses - Archive
A variety of solid tumors reveal oxygen deficiency as a result of rapid growth and insufficient tumor angiogenesis. Hypoxia in solid tumors appears to speed up malignant progression and metastatic potential of primary tumors thus leading to resistance against anticancer drugs and decreased response to radiotherapy.Of various in vivo non-invasive techniques to assess tumor hypoxia, oxygen-sensitive MRI (BOLD and TOLD) is an attractive and reliable option. Blood Oxygen Level Dependent (BOLD) and Tissue Oxygen Level Dependent (TOLD) MRI offer potential insight into tumor hypoxia. BOLD (Blood Oxygen Level Dependant) contrast MRI which measures R2* (1/T2*) is sensitive to endogenous paramagnetic …
Development Of A Model To Simulate The Single-Limb Stance Phase Of Walking To Determine The Limits Of Stability, Clifford Lee Hancock
Development Of A Model To Simulate The Single-Limb Stance Phase Of Walking To Determine The Limits Of Stability, Clifford Lee Hancock
Bioengineering Theses - Archive
Falls during walking are the primary cause of injuries for older persons and present a high associated cost to society due to the resulting treatment. Hence, the control of balance while moving is an essential issue especially amongst the elderly population. Better understanding of why and how these falls occur could lead to better fall prevention methods, therapies, or devices. These changes could effectively decrease overall emergency room visits, create more room in hospitals for other demands, and decrease medical costs for fall-related disabilities and deaths amongst patients overall. This study attempted to develop an inverted pendulum model of the …
Microfluidic Device For Determining Preferential Cell Migration Toward Extracellular Matrix Proteins, Neil Hall
Microfluidic Device For Determining Preferential Cell Migration Toward Extracellular Matrix Proteins, Neil Hall
Bioengineering Theses - Archive
Extracellular matrix (ECM) proteins interact with cells in bodily microenvironments by influencing their essential cellular processes in growth, survival, migration and repair after injury. In this study, a novel microfluidic device was developed to study preferential interactions of cells with multiple extracellular matrix proteins simultaneously in an unbiased manner. The implementation of PDITC-treated glass and a controlled laminar flow of multiple separated, soluble proteins was used to create an unbiased microenvironment in which ECM proteins are adsorbed on the glass surface in a manner that simultaneously exposes cells to multiple proteins, and allows them to migrate or outgrow toward the …
Recombinant Expression, Purification And Kinetic Characterization Of F₄₂₀-Cofactor Dependent Glucose-6-Phosphate Dehydrogenase From Mycobacterium Tuberculosis, Tijani Osumah
Bioengineering Theses - Archive
The FGD (F₄₂₀-dependent Glucose-6-phosphate dehydrogenase) enzyme is an F₄₂₀ Cofactor (7,8-didemethyl-8-hydroxy-5-deazariboflavin) dependent enzyme found in Mycobacterium tuberculosis, the causative agent of tuberculosis (TB). TB is still a prominent cause of illness and death worldwide. Because FGD is not found in humans, makes it a good target for drug development. By understanding the hydride transfer mechanism of the FGD in detail, we can aid in the improvement of drug targeting and development for the treatment of TB. FGD catalyzes the conversion of glucose-6-phosphate to 6-phosophogluconolactone. This project focuses on the purification and kinetic characterization of recombinant FGD using steady-state and pre-steady …
Investigation Of Nanoparticle Delivery To Cancer Cells By Conjugation With Various Targeting Moieties, Leila Hossein Rashidi
Investigation Of Nanoparticle Delivery To Cancer Cells By Conjugation With Various Targeting Moieties, Leila Hossein Rashidi
Bioengineering Theses - Archive
Recently, mapping and profiling of specific tumor biomarkers characterizing cancer cells, followed by understanding of signal cascades involved in the pathogenesis of tumors (targeted therapy), as well as diagnosis in early stages, have become promising topics in cancer research. Since, the most considerable limitations of conventional therapies and diagnostic modalities are associated with nonspecific targeting; designing intelligent new anti-cancer nanocarries improved by targeting biomolecules could enhance therapeutic efficiencies as well as diagnosis in early stage of cancer. Active targeting which is based on the surface accessibility and the high level of expression of specific cancer antigens has attracted much attention …
Effect Of Body Mass Index On The Biomechanical Properties Of Anterior Vaginal Wall Tissue Of Prolapsed Patients, Sandra Gabriela Ochoa Lopez
Effect Of Body Mass Index On The Biomechanical Properties Of Anterior Vaginal Wall Tissue Of Prolapsed Patients, Sandra Gabriela Ochoa Lopez
Bioengineering Theses - Archive
Anterior Vaginal Wall (AVW) prolapse is a bothersome condition that affects thousands of women. Its onset and progression is not well understood but is thought to be multifactorial. Biomechanical properties of AVW tissue from prolapsed patients have been measured in-vitro using excised tissue specimens with great variability found in results, possibly from differences in tissue preparation, setting, preservation time, temperature, hydration, etc. In-vivo test using a BTC-2000TM cutometer-like device has recently been developed that measures the tissue uplift under suction pressure load. In this study, a systematical analysis of biomechanical property measurements from AVW tissues was done, including both in-vitro …
Measurement Of Transverse Relaxation Times Of Cerebral Metabolites In Brain Tumors, Akshay Madan
Measurement Of Transverse Relaxation Times Of Cerebral Metabolites In Brain Tumors, Akshay Madan
Bioengineering Theses - Archive
Proton (¹H) magnetic resonance spectroscopy (MRS) provides a non-invasive means of assessing metabolite concentration for a range of biologically important cerebral compounds in vivo. To extract quantitative information, additional data regarding proton spin relaxation phenomena is critical. Transverse relaxation times (T₂) of cellular metabolites depend on the local molecular environment in which they reside. Several neurological diseases alter the molecular environment, which may be reflected in the changes of the T₂ relaxation times. Therefore alterations in T₂ in tumors may provide important information about the local environment and a potential non-invasive diagnostic tool. Thirty-seven adult patients with gliomas and 11 …
Microfluidic Chip-Based Fabrication Of Hollow Alginate Microfiber For Enzyme Entrapment And Reaction, Uyen Hoang Thao Pham
Microfluidic Chip-Based Fabrication Of Hollow Alginate Microfiber For Enzyme Entrapment And Reaction, Uyen Hoang Thao Pham
Bioengineering Theses - Archive
This thesis demonstrates a simple process to generate alginate hollow microfibers by using a non-lithographic PDMS microfluidic device. The microfluidic device was fabricated by a novel template method in a wet lab without the support of any conventional lithography techniques. The relationships of the flow rate and the diameter of hollow alginate fibers were characterized. It was found that the outer diameter of the alginate hollow fiber was independent of the flow rate, but the core flow and sheath flow played an important role to control the internal diameter and the wall thickness of the alginate hollow microfiber. At a …
Design, Fabrication And Evaluation Of A Novel Microfluidic Based In Vitro Cell Migration Assay, Sai Sirisha Dhavala
Design, Fabrication And Evaluation Of A Novel Microfluidic Based In Vitro Cell Migration Assay, Sai Sirisha Dhavala
Bioengineering Theses - Archive
Microfabrication and microfluidic devices have been recognized as potential platforms for cell-based and drug screening studies. Human glioblastoma multiforme (hGBM) cells migrate inside the central nervous system (CNS) in narrow space constrictions and rarely metastasize through bloodstream. Hence, microfluidic devices consisting of narrow channels are considered as suitable models to study cell migration in vitro. Further the migratory capability of each individual cell could be easily obtained and quantified using such system. This effort presents the design and development of an alternative microfluidic system that provides an integrated array of channels for screening multiple drugs simultaneously. This system is an …
Reliable Frontal Cortex Activity For An Oral Stroop Task Using Functional Near Infrared Spectroscopy, Matthew Allen Cloud
Reliable Frontal Cortex Activity For An Oral Stroop Task Using Functional Near Infrared Spectroscopy, Matthew Allen Cloud
Bioengineering Theses - Archive
Analysis tools such as HomER and NIRS-SPM for functional Near-Infrared systems are commercially or freely available; however, they are difficult for clinicians to use as an assessment tool. One barrier to their use is the reliability of a given functional test. Intraclass correlation coefficients (ICC) provide a measure of group and individual reliability. NIRS-SPM was extended with ICC to assess a two part modified Stroop task. The protocol was repeated once every two weeks over a period of one month. Changes in neural activity attributed to inhibition of distraction, show significant covariance to the protocol with moderate to strong reliability …
Development Of Gelatin Microbubble Based Plga Scaffold For Application In Bone Tissue Engineering, Krishna M. Shah
Development Of Gelatin Microbubble Based Plga Scaffold For Application In Bone Tissue Engineering, Krishna M. Shah
Bioengineering Theses - Archive
The overall goal of the study was to develop a delivery system for a potential bone tissue engineering application focusing on fabrication of gelatin microbubble (MB) based PLGA scaffolds capable of recruiting Mesenchymal stem cells (MSCs) and delivering bioactive molecules. Challenges associated with inefficient use of stem cells, scaffolding techniques and poor understanding of the role of growth factors hinders the success of tissue engineering strategies. A major challenge with the use of autologous stem cells is its low proliferation and migratory capacity. Our lab previously established that using a biomaterial implant, autologous MSCs can be directed and recruited in …
Development Of Magnetic-Based Multi-Layer Microparticles For Stem Cell Isolation, Enrichment And Detachment, Sonia Santimano
Development Of Magnetic-Based Multi-Layer Microparticles For Stem Cell Isolation, Enrichment And Detachment, Sonia Santimano
Bioengineering Theses - Archive
Stem cells have been studied and used in several cell-based therapies for regenerative medicine, 3D tissue-engineered scaffolds, and in vitro models for drug screening and testing. For instance, cell based therapy via the use of stem cells like Endothelial Progenitor Cells (EPCs) to treat patients with cardiovascular diseases, including ischemic heart disease, in-stent restenosis, and peripheral arterial occlusive disease. In addition, Circulating Cancer Cells (CSCs) have been used as an indication of cancer progression-free survival and for studying the mechanisms of tumor formation, metastasis, and anti-cancer drug screening. Due to their extensive diagnostic and therapeutic potential, various techniques have been …
Quantification And Comparisons Of Motion Metrics For Finger Tapping Performed By Children With Cerebral Palsy Before And After Therapy With Two Motion Tracking Camera Systems, Ankita H. Chainani
Quantification And Comparisons Of Motion Metrics For Finger Tapping Performed By Children With Cerebral Palsy Before And After Therapy With Two Motion Tracking Camera Systems, Ankita H. Chainani
Bioengineering Theses - Archive
The quantification of any improvements in the use of a paretic arm after children with cerebral palsy (CP) undergo rehabilitation is currently done by occupational therapists who administer a series of manual ability tests and assign a subjective score for each test task performed. In this work the hypothesis was explored of whether quantification of hand motion metrics by motion tracking while children with CP performed a hand tapping task could be used as a more quantitative surrogate for assessing how well these children control the use of their hand. To that end, two children with CP, both classified as …
Spectrophotometric Quantification Of Bilirubin In Sclera Of The Eye Using Visible Dlp® Hyperspectral Imaging, Naveen Balaji Balasubramanian
Spectrophotometric Quantification Of Bilirubin In Sclera Of The Eye Using Visible Dlp® Hyperspectral Imaging, Naveen Balaji Balasubramanian
Bioengineering Theses - Archive
In clinical settings doctors strive to give best care to the patients by looking for methods to diagnose the illness early to intervene with the necessary treatment. In the case of patients with liver problems (e.g. cirrhosis, hepatitis) an early indicator of impaired liver function is an increased concentration of bilirubin in the blood circulation. Bilirubin concentration is currently quantified by blood sampling, which is invasive, and it would be desirable to have a technology that quantifies bilirubin non-invasively. The goal of this work was to help address this clinical need and develop a methodology for determining non-invasively a measure …