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Full-Text Articles in Biomedical Engineering and Bioengineering

Neuromodulation Based Control Of Autonomous Robots On A Cloud Computing Platform, Cameron Muhammad Jan 2014

Neuromodulation Based Control Of Autonomous Robots On A Cloud Computing Platform, Cameron Muhammad

College of Graduate Studies: Theses & Dissertations

In recent years, the advancement of neurobiologically plausible models and computer networking has resulted in new ways of implementing control systems on robotic platforms. The work presents a control approach based on vertebrate neuromodulation and its implementation on autonomous robots in the open-source, open-access environment of robot operating system (ROS). A spiking neural network (SNN) is used to model the neuromodulatory function for generating context based behavioral responses of the robots to sensory input signals. The neural network incorporates three types of neurons- cholinergic and noradrenergic (ACh/NE) neurons for attention focusing and action selection, dopaminergic (DA) neurons for rewards- and …

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Fabrication And In Vivo Thrombogenecity Testing Of Nitric Oxide Generating Artificial Lungs, Kagya Amoako, Patrick Montoya, Terry C. Major, Ahmed B. Suhaib, Hitesh Handa, David O. Brant, Mark E. Meyerhoff, Robert H. Bartlett, Keith E. Cook Dec 2013

Fabrication And In Vivo Thrombogenecity Testing Of Nitric Oxide Generating Artificial Lungs, Kagya Amoako, Patrick Montoya, Terry C. Major, Ahmed B. Suhaib, Hitesh Handa, David O. Brant, Mark E. Meyerhoff, Robert H. Bartlett, Keith E. Cook

Mechanical and Industrial Engineering Faculty Publications

Hollow fiber artificial lungs are increasingly being used for long-term applications. However, clot formation limits their use to 1–2 weeks. This study investigated the effect of nitric oxide generating (NOgen) hollow fibers on artificial lung thrombogenicity. Silicone hollow fibers were fabricated to incorporate 50 nm copper particles as a catalyst for NO generation from the blood. Fibers with and without (control) these particles were incorporated into artificial lungs with a 0.1 m2 surface area and inserted in circuits coated tip-to-tip with the NOgen material. Circuits (N = 5/each) were attached to rabbits in a pumpless, arterio-venous configuration and run for …

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Near-Infrared Surface-Enhanced Fluorescence Using Silver Nanoparticles In Solution, Michael D. Furtaw Dec 2013

Near-Infrared Surface-Enhanced Fluorescence Using Silver Nanoparticles In Solution, Michael D. Furtaw

Department of Mechanical and Materials Engineering: Dissertations, Theses, and Student Research

Fluorescence spectroscopy is a widely used detection technology in many research and clinical assays. Further improvement to assay sensitivity may enable earlier diagnosis of disease, novel biomarker discovery, and ultimately, improved outcomes of clinical care along with reduction in costs. Near-infrared, surface-enhanced fluorescence (NIR-SEF) is a promising approach to improve assay sensitivity via simultaneous increase in signal with a reduction in background. This dissertation describes research conducted with the overall goal to determine the extent to which fluorescence in solution may be enhanced by altering specific variables involved in the formation of plasmonactive nanostructures of dye-labeled protein and silver nanoparticles …

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Simulation Of Vertical Axis Wind Turbines With Variable Pitch Foils, L. Damon Woods, John F. Gardner, Kurt S. Myers Nov 2013

Simulation Of Vertical Axis Wind Turbines With Variable Pitch Foils, L. Damon Woods, John F. Gardner, Kurt S. Myers

Mechanical and Biomedical Engineering Faculty Publications and Presentations

A dynamic computer model of a turbine was developed in MATLAB in order to study the behavior of vertical axis wind turbines (VAWTs) with variable pitch (articulating) foils. The simulation results corroborated the findings of several empirical studies on VAWTs. The model was used to analyze theories of pitch articulation and to inform the discussion on turbine design. Simulations of various models showed that pitch articulation allowed Darrieus-style vertical axis wind turbines to start from rest. Once in motion, the rotor was found to accelerate rapidly to very high rotational velocities. The simulations revealed a plateau region of high efficiency …

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Synthesis And Characterization Of Nucleic Acid-Functionalized Nanomaterials, Brianna S. Carroll, Jong Hyun Choi Oct 2013

Synthesis And Characterization Of Nucleic Acid-Functionalized Nanomaterials, Brianna S. Carroll, Jong Hyun Choi

The Summer Undergraduate Research Fellowship (SURF) Symposium

Motor proteins such as kinesin move along microtubules in order to transport cellular cargos throughout the cell by obtaining energy from RNA hydrolysis which allows the cell to complete the tasks needed to stay alive. In this work, we developed synthetic molecular motors using DNA enzymes (DNAzyme) and fluorescent nanomaterials which mimic the functions and structures of motor proteins. A DNAzyme-capped CdS nanoparticle and a RNA-functionalized single-walled carbon nanotube (SWCNT) were used as a walker and a track in the motor platform, respectively. As a walking mechanism, the DNAzyme cleaved the RNA substrates in the presence of metal cations. The …

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Formulation To Predict Lower Limb Muscle Forces During Gait, Gil Serrancolí, Jonathan P. Walter, Allison Kinney, A. Barjau, Benjamin J. Fregly, Josep M. Font-Llagunes Oct 2013

Formulation To Predict Lower Limb Muscle Forces During Gait, Gil Serrancolí, Jonathan P. Walter, Allison Kinney, A. Barjau, Benjamin J. Fregly, Josep M. Font-Llagunes

Mechanical and Aerospace Engineering Faculty Publications

The human body has more muscles than Degrees of Freedom (DoF), and that leads to indeterminacy in the muscle force calculation. This study proposes the formulation of an optimization problem to estimate the lower-limb muscle forces during a gait cycle of a patient wearing an instrumented knee prosthesis. The originality of that formulation consists of simulating muscle excitations in a physiological way while muscle parameters are calibrated. Two approaches have been considered. In Approach A, measured contact forces are applied to the model and all inverse dynamics loads are matched in order to get a physiological calibration of muscle parameters. …

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Sequential Structural And Fluid Dynamics Analysis Of Balloon-Expandable Coronary Stents., David Martin Oct 2013

Sequential Structural And Fluid Dynamics Analysis Of Balloon-Expandable Coronary Stents., David Martin

Doctoral

As in-stent restenosis following coronary stent deployment has been strongly linked with stent-induced arterial injury and altered vessel hemodynamics, the sequential numerical analysis of the mechanical and hemodynamic impact of stent deployment within a coronary artery is likely to provide an excellent indication of coronary stent performance. Despite this observation, very few numerical studies have considered both the mechanical and hemodynamic impact of stent deployment. In light of this observation, the aim of this research is to develop a robust numerical methodology for investigating the performance of balloon-expandable coronary stents in terms of their mechanical and hemodynamic impact within a …

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All-Optical Photoacoustic Detection Of Absorbers In Tissue Phantoms, Jami Johnson, Michelle Sabick, Kasper Vanwijk Sep 2013

All-Optical Photoacoustic Detection Of Absorbers In Tissue Phantoms, Jami Johnson, Michelle Sabick, Kasper Vanwijk

Mechanical and Biomedical Engineering Faculty Publications and Presentations

Visualizing and characterizing vascular structures is important for many areas of health care, from accessing difficult veins and arteries for laboratory testing, to diagnosis and treatment of cardiovascular disease. Photoacoustic (PA) imaging, one of the fastest growing fields of biomedical imaging, is well suited for this task. PA imaging is based on the photoacoustic effect, which starts with a pulsed laser source incident on biological tissue. If the wavelength of the source matches an absorption wavelength of a chromophore within the tissue, a portion of the pulse energy is absorbed by the chromophore and converted into heat. A subsequent increase …

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Finite Element Models Of The Knee & Hip Joints: Using Opensim To Predict Muscle Forces, Kevin S. Jones, Spencer D. Wangerin, Jeffrey D. Pyle, Stephen M. Klisch, Scott J. Hazelwood Aug 2013

Finite Element Models Of The Knee & Hip Joints: Using Opensim To Predict Muscle Forces, Kevin S. Jones, Spencer D. Wangerin, Jeffrey D. Pyle, Stephen M. Klisch, Scott J. Hazelwood

STAR Program Research Presentations

Quantitative data of stresses and strains in the cartilage of the knee and hip joints are required to design prostheses and can be used to give accurate advice to patients with cartilage damage as to which activities should be avoided. Instrumented hip implants can only give the overall resultant force in the joint, not the stresses and strains throughout the cartilage. Finite Element (FE) models of the Knee and Hip are being constructed in order to obtain the stresses and strains in articular (of the joint) cartilage. Muscle forces and joint contact forces are required as inputs to these FE …

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Stochastic Reconstruction Of Multiple Source Atmospheric Contaminant Dispersion Events, Derek Wade, Inanc Senocak Aug 2013

Stochastic Reconstruction Of Multiple Source Atmospheric Contaminant Dispersion Events, Derek Wade, Inanc Senocak

Mechanical and Biomedical Engineering Faculty Publications and Presentations

Reconstruction of intentional or accidental release of contaminants into the atmosphere using concentration measurements from a sensor network constitutes an inverse problem. An added complexity arises when the contaminant is released from multiple sources. Determining the correct number of sources is critical because an incorrect estimation could mislead and delay response efforts. We present a Bayesian inference method coupled with a composite ranking system to reconstruct multiple source contaminant release events. Our approach uses a multi-source data-driven Gaussian plume model as the forward model to predict the concentrations at sensor locations. Bayesian inference with Markov chain Monte Carlo (MCMC) sampling …

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Design Of A Compliant Underactuated Robotic Finger With Coordinated Stiffness, Etienne Dessauw Aug 2013

Design Of A Compliant Underactuated Robotic Finger With Coordinated Stiffness, Etienne Dessauw

Department of Mechanical and Materials Engineering: Dissertations, Theses, and Student Research

The concept of underactuation has been previously developed in the robotic field for grasping applications. For these anthropomorphic grippers, the minimization of the number of input signals, or in other words underactuation, is the most expected characteristic. This method has become very popular in recent decades. Indeed, by minimizing the number of input signals, it minimizes the complexity of the system’s control and at the same time avoids increased weight and cost. The inconvenience of such a technique is that the design of this type of system remains a difficult task if the behavior of the underactuated set of joints …

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Optimization Problem Formulation For Predicting Knee Muscle And Contact Forces During Gait, Gil Serrancolí, Jonathan P. Walter, Allison Kinney, Benjamin J. Fregly, Josep M. Font-Llagunes Aug 2013

Optimization Problem Formulation For Predicting Knee Muscle And Contact Forces During Gait, Gil Serrancolí, Jonathan P. Walter, Allison Kinney, Benjamin J. Fregly, Josep M. Font-Llagunes

Mechanical and Aerospace Engineering Faculty Publications

The human body has more muscles than degrees of freedom (DOF), which leads to indeterminacy in the muscle force calculation. In this study, an optimization problem to estimate the lower-limb muscle forces during a gait cycle of a patient wearing an instrumented knee prosthesis is formulated. It consists of simulating muscle excitations in a physiological way while muscle parameters are calibrated.

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Subtalar Joint Instability: Diagnosis And Conservative Treatment, Julie Choisne Jul 2013

Subtalar Joint Instability: Diagnosis And Conservative Treatment, Julie Choisne

Mechanical & Aerospace Engineering Theses & Dissertations

Subtalar instability may be caused by various ligamentous injuries. Combined instability at the ankle and subtalar joint is not adequately diagnosed. Further, isolated subtalar instability is usually misdiagnosed which may lead to long term damage to the joint. Developing a non-invasive and clinically practical tool to diagnose subtalar joint instability would be an important asset. The ability of an ankle brace, a common treatment for hindfoot instability, to promote stability for the subtalar joint was not well established. The purposes of this study were to 1) assess the kinematics of the subtalar, ankle, and hindfoot in the presence of isolated …

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Quantitative Assessment Of Program Outcomes Using Longitudinal Data From The Fe Exam, Joe C. Guarino, James R. Ferguson, V. Krishna C. Pakala Jun 2013

Quantitative Assessment Of Program Outcomes Using Longitudinal Data From The Fe Exam, Joe C. Guarino, James R. Ferguson, V. Krishna C. Pakala

Mechanical and Biomedical Engineering Faculty Publications and Presentations

There have been many studies providing details on using results from the Fundamentals of Engineering (FE) exam as metrics for meeting ABET program outcomes1. However, implementing an FE-based set of metrics poses challenges not limited to assessing validity of results. Programs using FE-based metrics must also determine the position of the metrics in the overall assessment process. We present a method for using FE-based metrics as an integral part of the ABET program assessment process. The principle issues we address are: (1) The validity of using FE metrics for a group of graduating students when not all of …

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In Vitro And In Vivo Study Of Sustained Nitric Oxide Release Coating Using Diazeniumdiolate-Doped Poly(Vinyl Chloride) Matrix With Poly(Lactide-Co-Glycolide) Additive, Hitesh Handa, Elizabeth J. Brisbois, Terry E. Robinson, Lahdan Refahiyat, Kagya Amoako, Robert H. Bartlett, Mark E. Meyerhoff Jun 2013

In Vitro And In Vivo Study Of Sustained Nitric Oxide Release Coating Using Diazeniumdiolate-Doped Poly(Vinyl Chloride) Matrix With Poly(Lactide-Co-Glycolide) Additive, Hitesh Handa, Elizabeth J. Brisbois, Terry E. Robinson, Lahdan Refahiyat, Kagya Amoako, Robert H. Bartlett, Mark E. Meyerhoff

Mechanical and Industrial Engineering Faculty Publications

Nitric oxide (NO) is an endogenous vasodilator as well as natural inhibitor of platelet adhesion and activation that can be released from a NO donor species, such as diazeniumdiolated dibutylhexanediamine (DBHD/N2O2) within a polymer coating. In this study, various Food and Drug Administration approved poly(lactic-co-glycolic acid) (PLGA) species were evaluated as additives to promote a prolonged NO release from DBHD/N2O2 within a plasticized poly(vinyl chloride) (PVC) matrix. When using an ester-capped PLGA additive with a slow hydrolysis time, the resulting coatings continuously release between 7 and 18 × 10−10 mol cm−2 min−1 NO for 14 days at 37 °C in …

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Edwards Lifesciences - Skirt To Frame Attachment Manufacturing Aid, Samuel Joda, Cesar Grimaldo, Patrick Hutchinson Jun 2013

Edwards Lifesciences - Skirt To Frame Attachment Manufacturing Aid, Samuel Joda, Cesar Grimaldo, Patrick Hutchinson

Mechanical Engineering

No abstract provided.

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Design And Development Of A Stair Ascension Assistive Device For Transfemoral Amputees, Casey Michael Barbarino Jun 2013

Design And Development Of A Stair Ascension Assistive Device For Transfemoral Amputees, Casey Michael Barbarino

Master's Theses

Transfemoral amputees around the world experience increased difficulty in climbing stairs due to lack of muscle, balance, and other factors. The loss of a lower limb greatly diminishes the amount of natural force generation provided that is necessary to propel oneself up stairs. This study investigated possible solutions to the problem of stair ascension for transfemoral amputees by the means of designing and developing an externally attachable device to a prosthesis. The number of amputations from military service has greatly increased since 2008, which shows there is a clear need for assistive devices (Wenke, Krueger, & Ficke, 2012). With the …

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Beach Wheelchair Project, Rory Aronson, Joshua Marcum, Samuel Coyne, Alex Hayes, Alexa Colburn, Max Hessel, Benedikt Strauss, Marvin Rimmele, Marco Pietsch Jun 2013

Beach Wheelchair Project, Rory Aronson, Joshua Marcum, Samuel Coyne, Alex Hayes, Alexa Colburn, Max Hessel, Benedikt Strauss, Marvin Rimmele, Marco Pietsch

Mechanical Engineering

The Beach Wheelchair, Sandcrawler, is a machine intended to help give people with disabilities the full beach experience. The non-profit organization Bridge II Sports sponsored this project, and tasked us with developing the design and fabricating a prototype. This chair has several features including a linkage mechanism that raises and lowers a chair relative to an external frame, hand crank drive with Gates Carbondrive belt and sprockets, buoyant Wheeleez balloon tires, and much more.

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Stent Graft Blush, Vanessa Barrett, Thomas Matzinger, Mike Morelli Jun 2013

Stent Graft Blush, Vanessa Barrett, Thomas Matzinger, Mike Morelli

Mechanical Engineering

In order to better understand Type IV endoleaks (“blush”), the Cal Poly Senior Project team GraftTest has developed a blush evaluation system able to mimic several of the aorta’s environmental parameters. Capable of both pressure and flow rate control, this bench top system accommodates Medtronic’s wide range of abdominal and thoracic aortic stent grafts. Having researched endoleaks, stent grafts, and numerous other factors affecting stent graft blush, a system was developed with the aim of assessing and comparing the performance of Medtronic’s stent grafts with regard to blush. Furthermore, this system has been designed to provide reliable and repeatable results …

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Guidance System, Kayaking For The Visually Impaired, D. Ryan Kirtland, Ryan Phife, William Gardner, Amy Johnson Jun 2013

Guidance System, Kayaking For The Visually Impaired, D. Ryan Kirtland, Ryan Phife, William Gardner, Amy Johnson

Biomedical Engineering

Quality Life Plus is working with Team River Runner to develop an assistive guidance system for veterans who want to remain active by kayaking, after sustaining an injury that impairs vision. This system allows these veterans to complete a slalom speed race independent of a personal guide in the water. The system incorporates 3 stations that each contain a speaker connected to a microcontroller system covered by a Pelican Case on a custom made buoy. During the slalom race, a kayaker will travel from shore towards buoy #1 as it omits sound from the speaker. As the kayaker moves around …

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Design And Testing Of Novel Mouthguard With Intermediate Nitinol And Foam Layers, Adam Kessler May 2013

Design And Testing Of Novel Mouthguard With Intermediate Nitinol And Foam Layers, Adam Kessler

UNLV Theses, Dissertations, Professional Papers, and Capstones

It is the aim of this study to investigate a novel mouthguard design that incorporates the use of a nickel-titanium (Nitinol) layer and thin foam layer in addition to EVA layers. It is thought that the Nitinol layer can distribute the force of an impact and that the thin foam layer may absorb this distributed force better than a solid EVA mouthguard of the same thickness. Rectangular, flat coupons representative of several mouthguard configurations were constructed for testing using an instrumented drop-weight impact tower. The coupon configurations include a control made of laminated EVA, a group of laminated EVA and …

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Closed Loop Control Of A Cylindrical Tube Type Ionic Polymer Metal Composite (Ipmc), Benjamin Mead May 2013

Closed Loop Control Of A Cylindrical Tube Type Ionic Polymer Metal Composite (Ipmc), Benjamin Mead

UNLV Theses, Dissertations, Professional Papers, and Capstones

The goal of this research is to provide a framework for the integration of tube type, cylindrical Ionic Polymer Metal-Composite (IPMC) into conventional devices. IPMCs are one of the most widely used types of electro-active polymer actuator, due to their low electric driving potential and large deformation range. For this research a tube type IPMC was investigated. This IPMC has a circular cross section with four separate electrodes on its surface and a hole through the middle. The four electrodes allow for biaxial bending and accurate control of the tip location. One of the main advantages of using this type …

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Correlations Between Internal And External Power Outputs During Weightlifting Exercise, Kristof Kipp, Chad Harris, Michelle B. Sabick Apr 2013

Correlations Between Internal And External Power Outputs During Weightlifting Exercise, Kristof Kipp, Chad Harris, Michelle B. Sabick

Mechanical and Biomedical Engineering Faculty Publications and Presentations

Identifying loads that maximize mechanical power is important because training at such loads may optimize gains in dynamic athletic performance. The purpose of this study was to examine correlations between measures of external mechanical power output and internal mechanical joint power output across different loads during a weightlifting exercise. Ten subjects performed 3 sets of the clean exercise at 65, 75, and 85% of 1 repetition maximum (1RM). Peak external mechanical power output was calculated with 4 commonly used methods, whereas an inverse dynamics approach was used to calculate peak internal mechanical power output for the hip, knee, and ankle …

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Adaptive Human Control Gains During Precision Grip, Erik D. Engeberg Mar 2013

Adaptive Human Control Gains During Precision Grip, Erik D. Engeberg

Mechanical Engineering Faculty Research

Eight human test subjects attempted to track a desired position trajectory with an instrumented manipulandum (MN). The test subjects used the MN with three different levels of stiffness. A transfer function was developed to represent the human application of a precision grip from the data when the test subjects initially displaced the MN so as to learn the position mapping from the MN onto the display. Another transfer function was formed from the data of the remainder of the experiments, after significant displacement of the MN occurred. Both of these transfer functions accurately modelled the system dynamics for a portion …

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Novel Approach To Junctional Bleeding: Tourniquet Device Proposal For Battlefield Hemorrhage Control, Kyle W. Cabaniss Mar 2013

Novel Approach To Junctional Bleeding: Tourniquet Device Proposal For Battlefield Hemorrhage Control, Kyle W. Cabaniss

Master's Theses

This study investigated possible solutions to the current wartime problem of junctional hemorrhaging, or massive traumatic hemorrhaging in non-tourinquetable areas such as the neck, groin, or armpit. Junctional hemorrhaging has been identified as a major contributor to potentially survivable deaths seen on the battlefield today and therefore is a priority for the U.S. armed and coalition forces (Kragh et al., 2011a; Bozeman, 2011). Common tourniquets today are standard issue and carried by soldiers in the military, but are limited to distal extremity trauma. As the battlefield has changes however, trauma has transformed from commonly seen gunshot wounds to more extreme …

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Multi-Level Parallelism For Incompressible Flow Computations On Gpu Clusters, Dana A. Jacobsen, Inanc Senocak Jan 2013

Multi-Level Parallelism For Incompressible Flow Computations On Gpu Clusters, Dana A. Jacobsen, Inanc Senocak

Mechanical and Biomedical Engineering Faculty Publications and Presentations

We investigate multi-level parallelism on GPU clusters with MPI-CUDA and hybrid MPI-OpenMP-CUDA parallel implementations, in which all computations are done on the GPU using CUDA. We explore efficiency and scalability of incompressible flow computations using up to 256 GPUs on a problem with approximately 17.2 billion cells. Our work addresses some of the unique issues faced when merging fine-grain parallelism on the GPU using CUDA with coarse-grain parallelism that use either MPI or MPI-OpenMP for communications. We present three different strategies to overlap computations with communications, and systematically assess their impact on parallel performance on two different GPU clusters. Our …

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Systems Biology Of The Functional And Dysfunctional Endothelium, Jennifer Frueh, Nataly Maimari, Takayuki Homma, Sandra M. Bovens, Ryan M. Pedrigi, Leila Towhidi, Rob Krams Jan 2013

Systems Biology Of The Functional And Dysfunctional Endothelium, Jennifer Frueh, Nataly Maimari, Takayuki Homma, Sandra M. Bovens, Ryan M. Pedrigi, Leila Towhidi, Rob Krams

Department of Mechanical and Materials Engineering: Faculty Publications

This review provides an overview of the effect of blood flow on endothelial cell (EC) signalling pathways, applying microarray technologies to cultured cells, and in vivo studies of normal and atherosclerotic animals. It is found that in cultured ECs, 5–10% of genes are up- or down-regulated in response to fluid flow, whereas only 3–6% of genes are regulated by varying levels of fluid flow. Of all genes, 90%are regulated by the steady part of fluid flow and 10% by pulsatile components. The associated gene profiles show high variability from experiment to experiment depending on experimental conditions, and importantly, the bioinformatical …

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Distal Placement Of An End-To-Side Bypass Graft Anastomosis: A 3d Computational Study, John Di Cicco, Ayodeji Demuren Jan 2013

Distal Placement Of An End-To-Side Bypass Graft Anastomosis: A 3d Computational Study, John Di Cicco, Ayodeji Demuren

Mechanical & Aerospace Engineering Faculty Publications

A three-dimensional (3D) computational fluid dynamics study of shear rates around distal end-to-side anastomoses has been conducted. Three 51% and three 75% cross-sectional area-reduced 6 mm cylinders were modeled each with a bypass cylinder attached at a 30-degree angle at different placements distal to the constriction. Steady, incompressible, Newtonian blood flow was assumed, and the full Reynolds-averaged Navier-Stokes equations, turbulent kinetic energy, and specific dissipation rate equations were solved on a locally structured multiblock mesh with hexahedral elements. Consequently, distal placement of an end-to-side bypass graft anastomosis was found to have an influence on the shear rate magnitudes. For the …

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An Acoustic-Based Microfluidic Platform For Active Separation And Mixing, Myeong Chan Jo Jan 2013

An Acoustic-Based Microfluidic Platform For Active Separation And Mixing, Myeong Chan Jo

USF Tampa Graduate Theses and Dissertations

Particle separation is of great interest to many biological and biomedical applications. Flow-based methods have been used to sort particles and cells. However, the main challenge with flow based particle separation systems is the need for a sheath flow for successful operation. Existence of the sheath liquid dilutes the analyte, necessitates precise flow control between sample and sheath flow, requires a complicated design to create sheath flow and separation efficiency depends on the sheath liquid composition. In addition, current gold standard active separation techniques are only capable of separation based on particle size; hence, separation cannot be achieved for same-size …

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Induced Damping And Its Relationship To Beneficial Energy Harvesting In Dielectric Elastomers With Application To Walking, Heather L. Lai Jan 2013

Induced Damping And Its Relationship To Beneficial Energy Harvesting In Dielectric Elastomers With Application To Walking, Heather L. Lai

Wayne State University Dissertations

This dissertation presents a novel, interdisciplinary research which addresses the potential of applying soft polymeric materials to strategically harvest biomechanical energy in a beneficial manner for use as a viable, low power source for on-board electronics. Of particular interest are electroactive polymers (EAP), which unlike other types of electromechanical smart materials such as piezoelectric ceramics, which are often brittle, have low elastic modulus and can exhibit large strains without substantial stress generations. One type of EAP, the dielectric elastomer (DE), which utilizes electrostatic forces built up across the dielectric polymer to convert between electrical and mechanical energy, is employed in …

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