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2024

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Full-Text Articles in Engineering

Architecture As A Carbon-Based Practice, Qixin Yu Jun 2024

Architecture As A Carbon-Based Practice, Qixin Yu

Masters Theses

Carbon serves as both a silent protagonist and a looming antagonist in the narrative of architecture, shaping not only the physical structures we inhabit but also the ecological legacy we leave behind.

Centuries of human exploitation of the environment have led to climate and material crises. Shifting this dynamic requires action at micro (matter), meso (material), and macro (materiality) levels. Biogenic materials offer significant potential for carbon sequestration and present opportunities for the building industry to collaborate with nature rather than merely extract from it.

This thesis establishes a research and manufacturing practice that prioritizes material innovation, carbon sequestration, environmental …


The Effect Of Atomic Oxygen On Additively Manufactured Materials, Ryan Grogan Jun 2024

The Effect Of Atomic Oxygen On Additively Manufactured Materials, Ryan Grogan

Master's Theses

Additive manufacturing (AM) is a rapidly developing manufacturing method utilized in fields such as the aerospace industry. In-space AM is a technology of interest for the future of spaceflight, including on-orbit manufacturing. However, AM materials are subject to defects that may impact their performance in space-based applications. How these defects change the material’s reaction to the space environment, specifically atomic oxygen (AO), has only recently been explored. AO is a highly corrosive, dominant constituent in low Earth orbit that causes continuous erosion of spacecraft surfaces. The effect of AO on various AM materials is investigated in this thesis. Stainless steel, …


Communication Challenges And Lessons Learned For An International Research And Development Project, Ryan Fehrenbach Jun 2024

Communication Challenges And Lessons Learned For An International Research And Development Project, Ryan Fehrenbach

Construction Management

This paper discusses the importance of communication for an International Research and Development project given the timeline it takes to accomplish. With a Cal Poly team of 5 students, 2 professors as advisors, an off-campus external advisor, and the Moringa Connect team in Ghana, many forms of communication were utilized and documented throughout the duration of the project. For a project of this magnitude, it was crucial to establish clear forms of communication from the first discussions of the project for both the internal Cal Poly team and the external team in Ghana. Implementing shared documents such as a deliverable …


Skip The Grid: Pv System Installations In The Navajo Nation, Samuel Varney Jun 2024

Skip The Grid: Pv System Installations In The Navajo Nation, Samuel Varney

Construction Management

The Skip the Grid initiative is a collaborative effort between interdisciplinary California Polytechnic State University, San Luis Obispo students, SOLV Energy, and the non-profit organization Heart of America aiming to strengthen the quality of life for Navajo Nation families. Many of the Navajo Nation’s residents are not connected to the power grid and don’t have access to sustainable alternatives, and this project aims to combat this by installing photovoltaic energy panel systems with lights and a battery storage system in their homes. With the help and guidance of the Consolidated School District near Farmington New Mexico, the project team was …


Design, Estimate, And Cut-Sheet Of Playhouse For Girls Build Summer Academy, Miles Paul Miller Jun 2024

Design, Estimate, And Cut-Sheet Of Playhouse For Girls Build Summer Academy, Miles Paul Miller

Construction Management

This Project-Based-Project was inspired by the Girls Build Summer Academy which is run by Professor Stacy Kolegraff. The camp is a week-long and the group of girls will construct a playhouse from scratch. The camp is to immerse young girls into the construction industry. This senior project is composed of 3 different components which include the Design, Estimate, and Cut-sheet of the playhouse. The project did not have any type of needed funding. This project is aimed to create an in-depth but intuitive set of plans and directions to create the playhouse for the girls. This project’s goal is to …


Heavy Civil Estimating Utilizing Hcss Heavybid, Quintan Matthew Davis Jun 2024

Heavy Civil Estimating Utilizing Hcss Heavybid, Quintan Matthew Davis

Construction Management

The estimate process is an essential aspect of the construction industry. Understanding how bids are formed and being able to create one for yourself is critical in being able to really understand cost breakdown of a construction process. This paper will focus around the process in creating a presentation for Cal Poly students, breaking down HCSS HeavyBid and its functions. This project was created to address this idea of attempting to teach HeavyBid to Cal Poly future young engineers. This was particularly important because young students learn how to be a great young engineer in the construction field, however not …


Coolsplint: Inflammation Reduction Accessory, Laura C. Denney, Winston H. Giang, Aanchal Singh Jun 2024

Coolsplint: Inflammation Reduction Accessory, Laura C. Denney, Winston H. Giang, Aanchal Singh

Biomedical Engineering

This document outlines a project sponsored by Elizabeth Mentel and Michael Clausson that addresses the shortcomings in current splinting options, particularly for wrist fractures in elderly patients. Stakeholders include clinicians, patients, and emergency medical technicians. Multiple improvements can be made to current splinting options to help alleviate inflammation along with splint versatility, affordability, accessibility, and ease of use. After determining the critical customer requirements, the primary objective of this project was to find a way to manage inflammation. The project explores existing splinting solutions and proposes a new design that utilizes cooling rods to reduce inflammation. The document reviews various …


Cervical Spinal Cord Angiography And Vessel-Selective Perfusion Imaging In The Rat, Seongtaek Lee, Brian Schmit, Shekar N. Kurpad, Matthew D. Budde Jun 2024

Cervical Spinal Cord Angiography And Vessel-Selective Perfusion Imaging In The Rat, Seongtaek Lee, Brian Schmit, Shekar N. Kurpad, Matthew D. Budde

Biomedical Engineering Faculty Research and Publications

Arterial spin labeling (ASL) has been widely used to evaluate arterial blood and perfusion dynamics, particularly in the brain, but its application to the spinal cord has been limited. The purpose of this study was to optimize vessel-selective pseudocontinuous arterial spin labeling (pCASL) for angiographic and perfusion imaging of the rat cervical spinal cord. A pCASL preparation module was combined with a train of gradient echoes for dynamic angiography. The effects of the echo train flip angle, label duration, and a Cartesian or radial readout were compared to examine their effects on visualizing the segmental arteries and anterior spinal artery …


Recommendation Of Minimal Distal Tibial Length For Long Axis Coordinate System Definitions, Erika P. Muhlrad, Andrew C. Peterson, Abigail M. Anderson, Katelyn C. Aragon, Rich J. Lisonbee, Bruce A. Macwilliams, Karen M. Kruger, Amy L. Lenz Jun 2024

Recommendation Of Minimal Distal Tibial Length For Long Axis Coordinate System Definitions, Erika P. Muhlrad, Andrew C. Peterson, Abigail M. Anderson, Katelyn C. Aragon, Rich J. Lisonbee, Bruce A. Macwilliams, Karen M. Kruger, Amy L. Lenz

Biomedical Engineering Faculty Research and Publications

Accurate anatomical coordinate systems for the foot and ankle are critical for interpreting their complex biomechanics. The tibial superior-inferior axis is crucial for analyzing joint kinematics, influencing bone motion analysis during gait using CT imaging and biplane fluoroscopy. However, the lack of consensus on how to define the tibial axis has led to variability in research, hindering generalizability. Even as advanced imaging techniques evolve, including biplane fluoroscopy and weightbearing CT, there exist limitations to imaging the entire foot together with the full length of the tibia. These limitations highlight the need to refine axis definitions. This study investigated various superior-inferior …


An Analytical Investigation Into Solute Transport And Sorption Via Intra-Particle Diffusion In The Dual-Porosity Limit, Lucy C. Auton, Maria Aguareles, Abel Valverde, Timothy G. Myers, Marc Calvo-Schwarzwalder Jun 2024

An Analytical Investigation Into Solute Transport And Sorption Via Intra-Particle Diffusion In The Dual-Porosity Limit, Lucy C. Auton, Maria Aguareles, Abel Valverde, Timothy G. Myers, Marc Calvo-Schwarzwalder

All Works

We develop a mathematical model for adsorption based on averaging the flow around, and diffusion inside, adsorbent particles in a column. The model involves three coupled partial differential equations for the contaminant concentration both in the carrier fluid and within the particle as well as the adsorption rate. The adsorption rate is modelled using the Sips equation, which is suitable for describing both physical and chemical adsorption mechanisms. Non-dimensionalisation is used to determine the controlling parameter groups as well as to determine negligible terms and so reduce the system complexity. The inclusion of intra-particle diffusion introduces new dimensionless parameters to …


Printed Graphite Electrodes For Fast-Charging Lithium-Ion Batteries, Guanyi Wang Jun 2024

Printed Graphite Electrodes For Fast-Charging Lithium-Ion Batteries, Guanyi Wang

Dissertations

The rapid growth of the electric vehicle (EV) market has demanded lithium-ion batteries (LIBs) with high energy density and fast charging capability. However, charging energy-dense LIBs with thick graphite electrodes at high current densities is typically facing challenges and leading to adverse performance, such as low energy density, short cycle life, rapid temperature rises and safety issues. The root cause is the onset of Li plating. During fast charging application, the sluggish lithium ions accumulated at the surface of graphite due to kinetic limitation and formed Li plating, especially when lithiated to a high state of charge (SOC). It has …


Exporting Sysml Designs To Simulink, Drew Q. Broadbent Jun 2024

Exporting Sysml Designs To Simulink, Drew Q. Broadbent

Theses and Dissertations

Various software systems have been developed to aid a systems engineer in evaluating system requirements, such as Dassault’s Magic System of Systems Architect (MSOSA) and MathWorks’ Simulink. Both software packages have different strengths; therefore, it is beneficial to export models from one software package to another. MSOSA provides a built-in tool that facilitates this transfer, built upon the Extension for Physical Interaction and Signal Flow Simulation (SysPhS) standard. However, the process is often unreliable and error prone and online documentation is largely lacking. This research used extensive trial and error to fill in the documentation gaps and create a method …


Disposal And Earth-Moon Escape From Cislunar Orbits Using Non-Linear Programming Techniques, Sam T. Loeffler Jun 2024

Disposal And Earth-Moon Escape From Cislunar Orbits Using Non-Linear Programming Techniques, Sam T. Loeffler

Theses and Dissertations

This thesis involves theoretical and numerical analysis of trajectories off of cislunar orbits to determine the reachability and escape of various impulsive Δ→v. The research will propagate trajectories using three body dynamics from various orbit families around the Earth-Moon Lagrange points and find low energy transfers that escape the Earth-Moon system. In order to achieve this, various different nonlinear programming solvers in MATLAB will be used to explore low energy impulsive escape transfers from common cislunar orbit families given long periods of computation time. After many points on cislunar orbits are analyzed, the data will be analyzed to …


Photodegradation Of Microplastics Through Nanomaterials: Insights Into Photocatalysts Modification And Detailed Mechanisms, Yiting Xiao, Yang Tian, Wenbo Xu, Jun Zhu Jun 2024

Photodegradation Of Microplastics Through Nanomaterials: Insights Into Photocatalysts Modification And Detailed Mechanisms, Yiting Xiao, Yang Tian, Wenbo Xu, Jun Zhu

Biological and Agricultural Engineering Faculty Publications and Presentations

Microplastics (MPs) pose a profound environmental challenge, impacting ecosystems and human health through mechanisms such as bioaccumulation and ecosystem contamination. While traditional water treatment methods can partially remove microplastics, their limitations highlight the need for innovative green approaches like photodegradation to ensure more effective and sustainable removal. This review explores the potential of nanomaterial-enhanced photocatalysts in addressing this issue. Utilizing their unique properties like large surface area and tunable bandgap, nanomaterials significantly improve degradation efficiency. Different strategies for photocatalyst modification to improve photocatalytic performance are thoroughly summarized, with a particular emphasis on element doping and heterojunction construction. Furthermore, this review …


Simulation Of Heat And Mass Transfer In A Refractance Window Dryer For Aloe Vera Gel, A. Shahraki, M. Khojastehpour, M. R. Golzarian, E. Azarpazhooh Jun 2024

Simulation Of Heat And Mass Transfer In A Refractance Window Dryer For Aloe Vera Gel, A. Shahraki, M. Khojastehpour, M. R. Golzarian, E. Azarpazhooh

Research outputs 2022 to 2026

Introduction Drying is one of the oldest methods of food preservation. To increase the efficiency of heat and mass transfer while maintaining product quality, the study of the drying process is crucial scientifically and meticulously. It is possible to conduct experimental tests, trial and error, in the drying process. However, this approach consumes time and cost, with a significant amount of energy resources. By harnessing available software and leveraging technological advancement to develop a general model for drying food under varying initial conditions, the drying process can be significantly optimized. Materials and Methods This study was conducted with the aim …


Recent Innovations In Laser Additive Manufacturing Of Titanium Alloys, Jinlong Su, Fulin Jiang, Jie Teng, Lequn Chen, Ming Yan, Guillermo Requena, Lai-Chang Zhang, Y. Morris Wang, Ilya V. Okulov, Hongmei Zhu, Chaolin Tan Jun 2024

Recent Innovations In Laser Additive Manufacturing Of Titanium Alloys, Jinlong Su, Fulin Jiang, Jie Teng, Lequn Chen, Ming Yan, Guillermo Requena, Lai-Chang Zhang, Y. Morris Wang, Ilya V. Okulov, Hongmei Zhu, Chaolin Tan

Research outputs 2022 to 2026

Titanium (Ti) alloys are widely used in high-tech fields like aerospace and biomedical engineering. Laser additive manufacturing (LAM), as an innovative technology, is the key driver for the development of Ti alloys. Despite the significant advancements in LAM of Ti alloys, there remain challenges that need further research and development efforts. To recap the potential of LAM high-performance Ti alloy, this article systematically reviews LAM Ti alloys with up-to-date information on process, materials, and properties. Several feasible solutions to advance LAM Ti alloys are reviewed, including intelligent process parameters optimization, LAM process innovation with auxiliary fields and novel Ti alloys …


Optimizing Recombinant Cas9 Expression: Insights From E. Coli Bl21(De3) Strains For Enhanced Protein Purification And Genome Editing, Shilpi Agrawal, Made Harumi Padmaswari, Abbey L. Stokes, Daniel Maxenberger, Morgan Reese, Adila Khalil, Christopher E. Nelson Jun 2024

Optimizing Recombinant Cas9 Expression: Insights From E. Coli Bl21(De3) Strains For Enhanced Protein Purification And Genome Editing, Shilpi Agrawal, Made Harumi Padmaswari, Abbey L. Stokes, Daniel Maxenberger, Morgan Reese, Adila Khalil, Christopher E. Nelson

Biomedical Engineering Faculty Publications and Presentations

The CRISPR-Cas9 system is a revolutionary tool in genetic engineering, offering unprecedented precision and efficiency in genome editing. Cas9, an enzyme derived from bacteria, is guided by RNA to edit DNA sequences within cells precisely. However, while CRISPR-Cas9 presents notable benefits and encouraging outcomes as a molecular tool and a potential therapeutic agent, the process of producing and purifying recombinant Cas9 protein remains a formidable hurdle. In this study, we systematically investigated the expression of recombinant SpCas9-His in four distinct Escherichia coli (E. coli) strains (Rosetta2, BL21(DE3), BL21(DE3)-pLysS, and BL21(DE3)-Star). Through optimization of culture conditions, including temperature and …


Smart Robot Design And Implementation To Assist Pedestrian Road Crossing, Hovannes Kulhandjian Jun 2024

Smart Robot Design And Implementation To Assist Pedestrian Road Crossing, Hovannes Kulhandjian

Mineta Transportation Institute

This research focuses on designing and developing a smart robot to assist pedestrians with road crossings. Pedestrian safety is a major concern, as highlighted by the high annual rates of fatalities and injuries. In 2020, the United States recorded 6,516 pedestrian fatalities and approximately 55,000 injuries, with children under 16 being especially vulnerable. This project aims to address this need by offering an innovative solution that prioritizes real-time detection and intelligent decision-making at intersections. Unlike existing studies that rely on traffic light infrastructure, our approach accurately identifies both vehicles and pedestrians at intersections, creating a comprehensive safety system. Our strategy …


A Data-Driven Agent-Based Model Of Occupants’ Thermal Comfort Behaviors For The Planning Of District-Scale Flexible Work Arrangements, Martín Mosteiro-Romero, Matias Quintana, Rudi Stouffs, Clayton Miller Jun 2024

A Data-Driven Agent-Based Model Of Occupants’ Thermal Comfort Behaviors For The Planning Of District-Scale Flexible Work Arrangements, Martín Mosteiro-Romero, Matias Quintana, Rudi Stouffs, Clayton Miller

Research Collection College of Integrative Studies

In a global context of increasing flexibility in the way workplaces and the districts in which they are located are used, there is a need for occupant-driven approaches to plan urban energy systems. Several authors have suggested the use of agent-based models (ABM) of building occupants in urban building energy simulations due to their ability to reproduce emergent behaviors from individual agents’ actions. However, few works in the literature take full advantage of the ABM paradigm, accounting for both occupant presence and energy-relevant behaviors at the district scale. In this work, we propose a methodology to develop a data-driven, agent-based …


3d Automated Surgeon’S Hand Motion Assessment Using A Cascade Fuzzy Supervisor During Intelligent Box-Trainer System Skills Training In A Multi-Thread Video Processing, Fatemeh Rashidi Fathabadi Jun 2024

3d Automated Surgeon’S Hand Motion Assessment Using A Cascade Fuzzy Supervisor During Intelligent Box-Trainer System Skills Training In A Multi-Thread Video Processing, Fatemeh Rashidi Fathabadi

Dissertations

For certain surgical procedures, Minimally Invasive Surgery (MIS) has become more advantageous than traditional open surgery. Therefore, mastery of laparoscopic skills is an essential component of surgical training and requires considerable time and effort. The Fundamentals of Laparoscopic Surgery (FLS) program has been developed as a tool to improve and assess fundamental surgical skills. In fact, using a low-cost Box-Trainer or a simulator, laparoscopic surgeons are required to train using a set of structured tasks that can be objectively used to assess their laparoscopic skills, which must be mastered before carrying out real-life laparoscopic procedures. These tasks include peg transfer, …


Creating Advanced Processes Through Utilizing Renewable Eutectics For Gas Capture And Separation, Ahmad Mohammad Rasheed Al-Bodour Jun 2024

Creating Advanced Processes Through Utilizing Renewable Eutectics For Gas Capture And Separation, Ahmad Mohammad Rasheed Al-Bodour

Dissertations

Global efforts to reduce emissions of environmentally harmful gases have intensified, with carbon dioxide (CO2) being identified as the most significant greenhouse gas and a key target for reduction strategies. Carbon dioxide (CO2) has the highest potential of threatening the environment. It is recognized as one of the greenhouse gases which has the potential of negative effects on the human being, atmosphere, and the environment. Even though CO2 gas has negative effects but at the same time it has high potential to be exploited in beneficial ways. For instance, CO2 is used in the energy field to produce the so-called …


Impact Of Operational Ladar Occlusions On Point Cloud Instance Segmentation, Andrew D. Gibson Jun 2024

Impact Of Operational Ladar Occlusions On Point Cloud Instance Segmentation, Andrew D. Gibson

Theses and Dissertations

Data exploitation techniques are the enabler for technological advancements in military ISR applications of ladar ISR. By identifying instances of military objects in observed scenes, point cloud deep learning models can unlock new standards of real-time information delivery to warfighters. Although current deep learning training datasets do not include real-world collection occlusions consistent with military applications, this research characterizes SPT model performance by adding occlusions to the DALESObjects dataset via artificial flyby simulations.We find that a baseline model trained on unoccluded data suffers performance degradation on both semantic and instance segmentation tasks when evaluated on occluded data, but that the …


Developing A Lean Spacecraft Test And Evaluation Architecture For A Contested Space Domain, Stephen K. Tullino Jun 2024

Developing A Lean Spacecraft Test And Evaluation Architecture For A Contested Space Domain, Stephen K. Tullino

Theses and Dissertations

The US Space Force (USSF) is currently investigating possible opportunities to improve the testing paradigm of spacecraft in order to get assets on-orbit faster, while maintaining suitable quality to meet mission needs in a contested space environment. To support this goal, USSF’s approach to test and evaluation (T&E) is centered around the concept of integrated test. In this research, the space text lexicon is defined, addressing the ambiguities on exactly what integrated test is with respect to spacecraft systems development and on-orbit mission assurance. This research considered any statistical trends in categorical discrepancies (i.e., anomalies) during prelaunch integration and test …


Scaffold-Free Development Of Multicellular Tumor Spheroids With Spatial Characterization Of Structure And Metabolic Radial Profiles, Shelby N. Bess, Gaven K. Smart, Matthew J. Igoe, Timothy J. Muldoon Jun 2024

Scaffold-Free Development Of Multicellular Tumor Spheroids With Spatial Characterization Of Structure And Metabolic Radial Profiles, Shelby N. Bess, Gaven K. Smart, Matthew J. Igoe, Timothy J. Muldoon

Biomedical Engineering Faculty Publications and Presentations

Purpose

In vitro assays are essential for studying cellular biology, but traditional monolayer cultures fail to replicate the complex three-dimensional (3D) interactions of cells in living organisms. 3D culture systems offer a more accurate reflection of the cellular microenvironment. However, 3D cultures require robust and unique methods of characterization.

Methods

The goal of this study was to create a 3D spheroid model using cancer cells and macrophages, and to demonstrate a custom image analysis program to assess structural and metabolic changes across spheroid microregions.

Results

Structural characterization shows that cells at the necrotic core show high normalized fluorescence intensities of …


Dynamics Of An Airplane Wheel At Touchdown, Pirooz Mohazzabi, Sophia Gentile, Cristian Marquez May 2024

Dynamics Of An Airplane Wheel At Touchdown, Pirooz Mohazzabi, Sophia Gentile, Cristian Marquez

Journal of Aviation Technology and Engineering

The dynamics of tire skidding and wear of a commercial airplane during touchdown is discussed, and a simple analytical model is presented. It is suggested that prespinning of the wheels prior to touchdown is not only possible but also practical to prevent tire wear and damage to the runway and the ensuing environmental issues.


The Journey To Desensitization: A Mobile App For Oral Immunotherapy Patients, Madeleine Waldie May 2024

The Journey To Desensitization: A Mobile App For Oral Immunotherapy Patients, Madeleine Waldie

Computer Science and Engineering Senior Theses

Millions of individuals in the United States confront the daily challenges of food allergies, with the threat of potentially life-threatening reactions ever-present. Oral Immunotherapy (OIT) emerges as a beacon of hope in this landscape, gradually desensitizing patients to their allergens. This groundbreaking treatment, contrasting avoidance strategies, promises a life with fewer restrictions. However, it is a journey fraught with complexities, requiring rigorous adherence to protocols, emotional fortitude, and frequent medical supervision for patients. This thesis centers on the creation of an iPhone application tailored to OIT patients, leveraging Apple’s privacy and security features. The app integrates seamlessly with the Apple …


Sustainable And Cost-Effective Work Zone Scheduling On Two-Lane Highways With Managed Lanes, Ahmed Z. Edrees May 2024

Sustainable And Cost-Effective Work Zone Scheduling On Two-Lane Highways With Managed Lanes, Ahmed Z. Edrees

Dissertations

Roadway maintenance projects greatly influence the roadway capacity, resulting in potential traffic disturbances captured by delays. Additionally, costs associated with these projects tend to be exorbitantly extensive. Most agencies and planners try to find a solution that minimizes roadway maintenance costs, traffic delays, crash risks, and environmental impact.

Work zones on two-way two-lane roadway typically avoids high-demand periods. Lane-closure scenario is commonly used and converts the open lane into a phantom intersection, alternating two-direction movements on one lane with the help of a flagger or a temporary signal. Alternatively, using shoulders as temporarily managed lanes allows for simultaneous two-way movements …


Network Slicing And Noma Enabled Mobile Edge Computing For Next-Generation Networks, Mohammad Arif Hossain May 2024

Network Slicing And Noma Enabled Mobile Edge Computing For Next-Generation Networks, Mohammad Arif Hossain

Dissertations

The advent of next-generation wireless networks ushers in a new era of potential, harnessing cutting-edge technologies like mobile edge computing (MEC), non-orthogonal multiple access (NOMA), and network slicing as pivotal drivers of transformation. Within this landscape, an innovative approach is proposed by introducing a NOMA-enabled network slicing technique within MEC networks. This approach aims to achieve multiple objectives: meeting stringent quality of service requirements, minimizing service latency, and enhancing spectral efficiency. By seamlessly integrating NOMA with network slicing in edge computing environments, significant reductions in overall latency are achieved, alongside ensuring optimal resource allocation for NOMA users. To address these …


Integrating Laser Charging And Drones For Secure Edge Computing, Weiqi Liu May 2024

Integrating Laser Charging And Drones For Secure Edge Computing, Weiqi Liu

Dissertations

Drone-mounted base stations (DBSs) have emerged as a promising solution to enhance the flexibility and coverage of wireless networks, potentially revolutionizing communication systems. This dissertation explores the integration of DBSs into 5G and beyond networks, focusing on methodologies to optimize their deployment and performance. A laser charging-enabled DBS framework is proposed to extend flight time and enhance network coverage. By leveraging laser charging technology, the DBS can receive continuous energy transmission from a ground-based charging station while providing communication services to users. The framework is formulated as an optimization problem to jointly maximize flight time and communication data rate, while …


Computational Microscopy For Biomedical Imaging With Deep Learning Assisted Image Analysis, Yuwei Liu May 2024

Computational Microscopy For Biomedical Imaging With Deep Learning Assisted Image Analysis, Yuwei Liu

Dissertations

Microscopy plays a crucial role across various scientific fields by enabling structural and functional imaging with microscopic resolution. In biomedicine, microscopy contributes to basic research and clinical diagnosis. Conventionally, optical microscopy derives its contrast from the amplitude of the optical wave and provides visualization of the physical structure of the sample qualitatively. To understand the function at the cellular or tissue level, there is a need to characterize the sample quantitatively and explore contrast mechanisms other than light intensity. Image enhancement or reconstruction from microscopic imaging systems is known as computational microscopy, and it involves the application of computational techniques …