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Articles 1861 - 1890 of 9778
Full-Text Articles in Engineering
Acoustophoresis Around An Elastic Scatterer In A Standing Wave Field, Khemraj Gautam Kshetri, Nitesh Nama
Acoustophoresis Around An Elastic Scatterer In A Standing Wave Field, Khemraj Gautam Kshetri, Nitesh Nama
Department of Mechanical and Materials Engineering: Faculty Publications
Acoustofluidic systems often employ prefabricated acoustic scatterers that perturb the imposed acoustic field to realize the acoustophoresis of immersed microparticles. We present a numerical study to investigate the timeaveraged streaming and radiation force fields around a scatterer. Based on the streaming and radiation force field, we obtain the trajectories of the immersed microparticles with varying sizes and identify a critical transition size at which the motion of immersed microparticles in the vicinity of a prefabricated scatterer shifts from being streaming dominated to radiation dominated. We consider a range of acoustic frequencies to reveal that the critical transition size decreases with …
Comparison Of Models With And Without Roadway Features To Estimate Annual Average Daily Traffic At Non-Coverage Locations, Jing Wang, Ryan Devine, Nathan Huynh, Weimin Jin, Gurcan Comert, Mashrur Chowdhury
Comparison Of Models With And Without Roadway Features To Estimate Annual Average Daily Traffic At Non-Coverage Locations, Jing Wang, Ryan Devine, Nathan Huynh, Weimin Jin, Gurcan Comert, Mashrur Chowdhury
Department of Civil and Environmental Engineering: Faculty Publications
This study develops and evaluates models to estimate Annual Average Daily Traffic (AADT) at non-coverage or out-of-network locations. The non-coverage locations are those where counts are performed very infrequently, but an up-to-date and accurate estimate is needed by state departments of transportation. Two types of models are developed, one that simply uses the nearby known AADTs to provide an estimate and one that requires roadway features (e.g., type of median, presence of left-turn lane). The advantage of the former type is that no additional data collection is needed, thereby saving time and money for state highway agencies. A natural question …
Feasibility And Outcomes Of Supplemental Gait Training By Robotic And Conventional Means In Acute Stroke Rehabilitation, Mukul Talaty, Alberto Esquenazi
Feasibility And Outcomes Of Supplemental Gait Training By Robotic And Conventional Means In Acute Stroke Rehabilitation, Mukul Talaty, Alberto Esquenazi
Moss-Magee Rehabilitation Papers
INTRODUCTION: Practicality of implementation and dosing of supplemental gait training in an acute stroke inpatient rehabilitation setting are not well studied but can have positive impact on outcomes.
OBJECTIVES: To determine the feasibility of early, intense supplemental gait training in inpatient stroke rehabilitation, compare functional outcomes and the specific mode of delivery.
DESIGN AND SETTING: Assessor blinded, randomized controlled trial in a tertiary Inpatient Rehabilitation Facility.
PARTICIPANTS: Thirty acute post-stroke patients with unilateral hemiparesis (≥ 18 years of age with a lower limb MAS ≤ 3).
INTERVENTION: Lokomat® or conventional gait training (CGT) in addition to standard mandated therapy time. …
Nitrogen Radiofrequency Plasma Treatment Of Graphene, Antoine Bident, Nathalie Caillault, Florence Delange, Christine Labrugere, Guillaume Aubert, Cyril Aymonier, Etienne Durand, Alain Demourgues, Yongfeng Lu, Jean-François Silvain
Nitrogen Radiofrequency Plasma Treatment Of Graphene, Antoine Bident, Nathalie Caillault, Florence Delange, Christine Labrugere, Guillaume Aubert, Cyril Aymonier, Etienne Durand, Alain Demourgues, Yongfeng Lu, Jean-François Silvain
Department of Electrical and Computer Engineering: Faculty Publications
The incorporation of nitrogen (N) atoms into a graphitic network such as graphene (Gr) remains a major challenge. However, even if the insertion mechanisms are not yet fully understood, it is certain that the modification of the electrical properties of Gr is possible according to the configuration adopted. Several simulations work, notably using DFT, have shown that the incorporation of N in Gr can induce an increase in the electrical conductivity and N acts as an electron donor; this increase is linked to the amount of N, the sp2/sp3 carbon configuration, and the nature of C-N bonding. …
Self-Dual Systems For Backscattering Cancellation, Nasim Mohammadi Estrakhri
Self-Dual Systems For Backscattering Cancellation, Nasim Mohammadi Estrakhri
Engineering Faculty Articles and Research
Using carefully arranged electric and magnetic components, we have recently demonstrated that backscattering from otherwise arbitrarily shaped two- and three-dimensional structures can be fully eliminated. Here, first we investigate the possibility of creating self-dual microwave absorbers that may provide advantages compared to typical commercial magnetoelectric absorbers. Next, we demonstrate that the self-duality condition is not limited to homogenous structures and may be extended to effective material properties, opening the door to realistic implementation of these structures at microwave and optical frequencies.
Power Allocation Stable Matching User Pairing (Smup) In Noma With Swipt, Bassem M. Saleh, Ahmed Elnakib, Sherif Kishk, Mohamed M. Ashour
Power Allocation Stable Matching User Pairing (Smup) In Noma With Swipt, Bassem M. Saleh, Ahmed Elnakib, Sherif Kishk, Mohamed M. Ashour
Mansoura Engineering Journal
Non-orthogonal multiple access (NOMA) is a potentially spectral efficient approach for beyond-fifth-generation wireless networks. This paper investigates the joint user pairing, and power allocation problem in a cooperative-NOMA (CNOMA) with simultaneous wireless information and power transfer (SWIPT) capabilities. The purpose of this work is to enhance the sum-rate of users with poor channel conditions while guaranteeing residual energy for paired users with good channel conditions as compensation for their cooperation. To overcome this challenge, we divided it into two parts: power allocation (PA) and user pairing (UP). The particle swarm-optimization (PSO) method is utilized to address the PA issue, whereas …
Investigation Of Greening Façade And Retrofitting Strategies On Outdoor Thermal Comfort And Indoor Energy Consumption In New Assiut City, Egypt, Amr Sayed Hassan Abdallah, Randa M. A. Mahmoud
Investigation Of Greening Façade And Retrofitting Strategies On Outdoor Thermal Comfort And Indoor Energy Consumption In New Assiut City, Egypt, Amr Sayed Hassan Abdallah, Randa M. A. Mahmoud
Mansoura Engineering Journal
This study aims to investigate the effect of greening façades and roofs on the outdoor thermal comfort of residences and indoor energy consumption within the context of different retrofitting strategies. The proposed methodology consists of two main stages, first Envi-met will be used to model the base case and study the effect of green walls and roofs on outdoor thermal comfort, then DesignBuilder will be used to estimate the annual energy consumption of the base case and six retrofitting strategies. An investigation was performed for a new residential complex Youth housing sector in New Assiut City as a model of …
Smart Sounding Table Using Adaptive Neuro-Fuzzy Inference System, Osman Ünal, Nuri Akkaş
Smart Sounding Table Using Adaptive Neuro-Fuzzy Inference System, Osman Ünal, Nuri Akkaş
Journal of Marine Science and Technology–Taiwan
Marine engineers measure the liquid level (sounding depth) to calculate the volumetric content of a ship's tank. The sounding depth is determined using an ullage pipe located at specific points on the tanks. To estimate the accurate volume of liquid, considering the ship's trim and heel conditions, engineers use a tank table (sounding table) consisting of hundreds of pages. However, this method is time-consuming and lacks intermediate values for sounding depth, trim, and heel. Ship designers recommend to use linear interpolation for intermediate values, yet this process is also time-consuming. This paper proposes the implementation of an Adaptive Neuro-Fuzzy Inference …
Case Study Of Coastal Erosion And Measures At Kezailiao Coast, Taiwan, Tai-Wen Hsu, Yi-Tse Tu, Jen-Yi Chang
Case Study Of Coastal Erosion And Measures At Kezailiao Coast, Taiwan, Tai-Wen Hsu, Yi-Tse Tu, Jen-Yi Chang
Journal of Marine Science and Technology–Taiwan
This paper examines major factors of coastal erosion and measures against beach erosion at Kezailiao Coast, Taiwan. Typical examples of coastal erosion due to natural or man-made factors are reviewed. Case studies of countermeasure for beach erosion are addressed. We further analyze and discuss historical shoreline and coastal cliff recession as a result of the attack of storm surges and waves. The coastline mainly made up of cliffs (2-3m high), made of soft, easily eroded boulder sand and clay. In total, 3km of land have been lost since 1951, including villages and farm buildings. The most important impacts of beach …
Wearable Sensor-Based Walkability Assessment At Ferry Terminal Using Machine Learning: A Case Study Of Mokpo, Korea, Jungyeon Choi, Hwayoung Kim
Wearable Sensor-Based Walkability Assessment At Ferry Terminal Using Machine Learning: A Case Study Of Mokpo, Korea, Jungyeon Choi, Hwayoung Kim
Journal of Marine Science and Technology–Taiwan
Walkability assessments are becoming more popular, as walking offers numerous health, environmental, and economic benefits to communities. However, previous studies on ferry terminal walkability assessment have been inadequate. This study aimed to develop a wearable sensor system to automatically assess walkability at ferry terminals without conducting surveys. We applied seven machine learning (ML) classifiers to detect different walking environments, including flat ground (FG), downhill slope (DS), uphill slope (US), and uneven surface (UE). The ML models were evaluated across different combinations of classes: 2-class (FG vs. UE), 3-class (U) (FG vs. US vs. UE), 3-class (D) (FG vs. DS vs. …
Application Of Blockchain Technology In Aquaculture Management, Yu-Jen Pan, Hsin-Pei Shieh
Application Of Blockchain Technology In Aquaculture Management, Yu-Jen Pan, Hsin-Pei Shieh
Journal of Marine Science and Technology–Taiwan
In recent years, food safety has become a growing concern in Taiwanese society. To ensure efficient management of the supply chain within the L Aquatic Products company, it is imperative to employ reliable technical support in establishing an effective traceability management system. The traceability of products can provide managers with valuable insight into the intricacies of the supply chain. By establishing a dependable food traceability system, brand trust can be strengthened, and consumers can inquire about the movement of aquatic products within the supply chain. Blockchain technology offers features such as traceability, accountability, transparency, reliability, trust, privacy, and security, making …
Production Of Ground Granulated Blast-Furnace Slag Cement: Energy And Carbon Reduction Efficiency Of Cement-Grinding System, Kuan-Hung Lin, Chung-Chia Yang
Production Of Ground Granulated Blast-Furnace Slag Cement: Energy And Carbon Reduction Efficiency Of Cement-Grinding System, Kuan-Hung Lin, Chung-Chia Yang
Journal of Marine Science and Technology–Taiwan
This study used clinker, ground granulated blast-furnace slag (GGBS), and gypsum in a cement-grinding system to produce GGBS cement (GCE). Gypsum was used as the alkaline activator to modify the surface area of GCE and increase its compressive strength. The results revealed that the use of the gypsum activator and the modification of the surface area of GCE effectively increased the formerly inadequate compressive strength of GCE (GGBS > 60%) in the early stage. In addition, energy consumption data were obtained during the production of GCE and Portland cement (PCE) by the cement-grinding system. The calculations concerning the production proportions indicated …
Awareness Of Cybersecurity And Its Relationship To Digital Transformation Among Supervisors Of The Education Department In Jazan Region, Maryam Y. Otaif
Awareness Of Cybersecurity And Its Relationship To Digital Transformation Among Supervisors Of The Education Department In Jazan Region, Maryam Y. Otaif
International Journal for Research in Education
The study aimed to identify the degree of awareness of cybersecurity, and to reveal the reality of digital transformation and the relationship between them from the point of view of the supervisors of the Education Department in the Jazan region. The study followed the descriptive correlative approach, by stratified random sampling (257). a questionnaire was built , The study found that the degree of cybersecurity awareness is high with an arithmetic mean of (3.48), and also degree of awareness of cybersecurity concepts is high, (3,52), and awareness of cybersecurity risks and violations (3.45), and it was found that the total …
Enabling Intelligent Network Management Through Multi-Agent Systems: An Implementation Of Autonomous Network System, Petro Mushidi Tshakwanda
Enabling Intelligent Network Management Through Multi-Agent Systems: An Implementation Of Autonomous Network System, Petro Mushidi Tshakwanda
Electrical and Computer Engineering ETDs
This Ph.D. dissertation presents a pioneering Multi-Agent System (MAS) approach for intelligent network management, particularly suited for next-generation networks like 5G and 6G. The thesis is segmented into four critical parts. Firstly, it contrasts the benefits of agent-based design over traditional micro-service architectures. Secondly, it elaborates on the implementation of network service agents in Python Agent Development Environment (PADE), employing machine learning and deep learning algorithms for performance evaluation. Thirdly, a new scalable approach, Scalable and Efficient DevOps (SE-DO), is introduced to optimize agent performance in resource-constrained settings. Fourthly, the dissertation delves into Quality of Service (QoS) and Radio Resource …
Multi-Factor Optimization Of Bio-Methanol Production Through Gasification Process Via Statistical Methodology Coupled With Genetic Algorithm, Amin Hedayati Moghaddam, Morteza Esfandyari, Dariush Jafari, Hossein Sakhaeinia
Multi-Factor Optimization Of Bio-Methanol Production Through Gasification Process Via Statistical Methodology Coupled With Genetic Algorithm, Amin Hedayati Moghaddam, Morteza Esfandyari, Dariush Jafari, Hossein Sakhaeinia
Department of Civil and Environmental Engineering: Faculty Publications
This work innovatively explores the bio-methanol production process, conducts comprehensive analyses, develops statistical models, and optimizes operational conditions, contributing valuable insights to the field of sustainable energy production from biomass. Accordingly, bio-methanol production from biomass through gasification route was investigated and simulated using Aspen Plus software. The effects of operational parameters on energy duty of gasification reactor and the methanol production rate in syngas to methanol reactor were investigated. The parameters affecting the process performance including temperature, pressure, and steam/feed ratio were examined using the response surface methodology (RSM) by central composite design (CCD) technique. Analysis of variance (ANOVA) was …
Multi-Factor Optimization Of Bio-Methanol Production Through Gasification Process Via Statistical Methodology Coupled With Genetic Algorithm, Amin Hedayati Moghaddam, Morteza Esfandyari, Dariush Jafari, Hossein Sakhaeinia
Multi-Factor Optimization Of Bio-Methanol Production Through Gasification Process Via Statistical Methodology Coupled With Genetic Algorithm, Amin Hedayati Moghaddam, Morteza Esfandyari, Dariush Jafari, Hossein Sakhaeinia
Department of Civil and Environmental Engineering: Faculty Publications
This work innovatively explores the bio-methanol production process, conducts comprehensive analyses, develops statistical models, and optimizes operational conditions, contributing valuable insights to the field of sustainable energy production from biomass. Accordingly, bio-methanol production from biomass through gasification route was investigated and simulated using Aspen Plus software. The effects of operational parameters on energy duty of gasification reactor and the methanol production rate in syngas to methanol reactor were investigated. The parameters affecting the process performance including temperature, pressure, and steam/feed ratio were examined using the response surface methodology (RSM) by central composite design (CCD) technique. Analysis of variance (ANOVA) was …
Overview Of Various Components Of Lateral Flow Immunochromatography Assay For The Detection Of Mycotoxins And Limit Of Detection In Food Samples: A Systematic Review, Vinayak Sharma, Thasmin Shahjahan, Bilal Javed, Furong Tian
Overview Of Various Components Of Lateral Flow Immunochromatography Assay For The Detection Of Mycotoxins And Limit Of Detection In Food Samples: A Systematic Review, Vinayak Sharma, Thasmin Shahjahan, Bilal Javed, Furong Tian
Articles
The detection of aflatoxins is essential for the food industry to ensure the safety and quality of food products before their release to the market. The lateral-flow immunochromatography assay (LFIA) is a simple technique that allows the rapid on-site detection of aflatoxins. The purpose of this review is to evaluate and compare the limits of detection reported in the most recent research articles, published between the years of 2015 and 2023. The limits of detection (LODs) were compared against the particle type and particle size, as well as other variables, to identify trends and correlations among the parameters. A growing …
درجة امتلاك معلمي الجغرافيا لمهارات استخدام تقنية نظم المعلومات الجغرافية جي آي أس في المدارس الحكومية في لواء دير علا, Afaf Omar Ibrahim Albalawneh
درجة امتلاك معلمي الجغرافيا لمهارات استخدام تقنية نظم المعلومات الجغرافية جي آي أس في المدارس الحكومية في لواء دير علا, Afaf Omar Ibrahim Albalawneh
Journal of the Association of Arab Universities for Research in Higher Education مجلة اتحاد الجامعات العربية للبحوث في التعليم العالي
هدفت المقال إلى البحث في درجة امتلاك معلمي الجغرافيا لمهارات استخدام تقنية نظم المعلومات الجغرافية (GIS) في المدارس الحكومية في لواء دير علا، تمّ توزيع الاستبانة بشكلها الإلكتروني، وتمّ استرداد (100) استبانة، اعتمدت الباحثة على المنهج الوصفي، وقامت الباحثة بتطوير أداة استبانة، وتكوّنت الاستبانة في صورتها النهائية من (19) فقرة موزعة على محورين، وأظهرت النتائج أن هناك فروقاً ذات دلالة إحصائية (0.05a=) تعزى لأثر الجنس وجاءت الفروق لصالح الذكور، هذا وأوصت الدراسة إلى ضرورة إجراء المزيد من الدراسات حول استخدام تقنية نظم المعلومات الجغرافية (GIS).
The article aimed to investigate the degree to which geography teachers possess the skills of …
Evolution Of Glassy Carbon Derived From Pyrolysis Of Furan Resin, Josh Kemppainen, Ivan Gallegos, Aaron Krieg, Jacob R. Gissinger, Kristopher E. Wise, Margaret Kowalik, Julia A. King, S. Gowtham, Adri Van Duin, Gregory Odegard
Evolution Of Glassy Carbon Derived From Pyrolysis Of Furan Resin, Josh Kemppainen, Ivan Gallegos, Aaron Krieg, Jacob R. Gissinger, Kristopher E. Wise, Margaret Kowalik, Julia A. King, S. Gowtham, Adri Van Duin, Gregory Odegard
Michigan Tech Publications
Glassy carbon (GC) material derived from pyrolyzed furan resin was modeled by using reactive molecular dynamics (MD) simulations. The MD polymerization simulation protocols to cure the furan resin precursor material are validated via comparison of the predicted density and Young's modulus with experimental values. The MD pyrolysis simulations protocols to pyrolyze the furan resin precursor is validated by comparison of calculated density, Young's modulus, carbon content, sp carbon content, the in-plane crystallite size, out-of-plane crystallite stacking height, and interplanar crystallite spacing with experimental results from the literature for furan resin derived GC. The modeling methodology established in this work can …
The Development Of A One-Shot Learning Machine Learning For Industrial Use With Predictive Maintenance, Conor O Brien
The Development Of A One-Shot Learning Machine Learning For Industrial Use With Predictive Maintenance, Conor O Brien
Theses
With the advent of Industry 4.0, Manufacturing operations have become more connected and automated. Modern industrial monitoring technology can monitor the performance of both the sensor utilised and the material under monitoring. This has led to a trend where legacy machines without this technology are being removed from production and/or not included in new reconfigurations of production lines, well before their productive lifespan had ended. A key driver for this is the difficulty in retrofitting Predictive Maintenance (PdM) systems to legacy machines, in part due to the machine-to-machine variation present in older machines. Accounting for this variation in PdM systems …
10.02.2023 Orsp Connect, Liz Williamson
State Space Modeling And Estimation Of Flexible Structure Using The Theory Of Functional Connections, Carlo Lombardi, Riccardo Bevilacqua
State Space Modeling And Estimation Of Flexible Structure Using The Theory Of Functional Connections, Carlo Lombardi, Riccardo Bevilacqua
Student Works
In this work, we present a novel method to model the dynamics of a continuous structure based on measurements taken at discrete points. The method is conceived to provide new instruments to address the problem of flexible dynamics modeling in a spacecraft, where an effective mathematical representation of the non-rigid behavior of the is of critical importance in the design of an effective and reliable attitude estimation and control system. Both the measurements and the model that describes the structure can be affected by uncertainty. The purpose of the developed method is to estimate the position and the velocity of …
Stability Of Deep Neural Networks For Feedback-Optimal Pinpoint Landings, Omkar S. Mulekar, Hancheol Cho, Riccardo Bevilacqua
Stability Of Deep Neural Networks For Feedback-Optimal Pinpoint Landings, Omkar S. Mulekar, Hancheol Cho, Riccardo Bevilacqua
Student Works
The ability to certify systems driven by neural networks is crucial for future rollouts of machine learning technologies in aerospace applications. In this study, the neural networks are used to represent a fuel-optimal feedback controller for two different 3-degree-of-freedom pinpoint landing problems. It is shown that the standard sum-ofsquares Lyapunov candidate is too restrictive to assess the stability of systems with fuel-optimal control profiles. Instead, a parametric Lyapunov candidate (i.e. a neural network) can be trained to sufficiently evaluate the closed-loop stability of fuel-optimal control profiles. Then, a stability-constrained imitation learning method is applied, which simultaneously trains a neural network …
Microstructural Characterization Of The Transition In Ss316l And In625 Bimetallic Fabricated Using Hybrid Additive Manufacturing, Christopher J. Bettencourt, Nadia Kouraytem
Microstructural Characterization Of The Transition In Ss316l And In625 Bimetallic Fabricated Using Hybrid Additive Manufacturing, Christopher J. Bettencourt, Nadia Kouraytem
Mechanical and Aerospace Engineering Faculty Publications
Nearly all energy technologies utilize heat exchangers and recuperators within the power cycle. To further improve the cost-effectiveness of recuperators, costly high temperature Inconel 625 superalloy was substituted with a more affordable Stainless Steel 316L to be used at the low-temperature side of the heat exchanger. Bimetallic samples for analysis and examination were fabricated by combining Laser Powder-bed Fusion and Directed Energy Deposition. Two transition strategies for joining to the laser powder-bed fusion steel were explored, namely, a direct transition and an intermediate layer of 50% nickel powder mixed with 50% steel powder through Directed Energy Deposition. The microstructure and …
Using Machine Learning To Predict Hypervelocity Fragment Propagation Of Space Debris Collisions, Katharine Larsen, Riccardo Bevilacqua
Using Machine Learning To Predict Hypervelocity Fragment Propagation Of Space Debris Collisions, Katharine Larsen, Riccardo Bevilacqua
Student Works
The future of spaceflight is threatened by the increasing amount of space debris, especially in the near-Earth environment. To continue operations, accurate characterization of hypervelocity fragment propagation following collisions and explosions is imperative. While large debris particles can be tracked by current methods, small particles are often missed. This paper presents a method to estimate fragment fly-out properties, such as fragment, velocity, and mass distributions, using machine learning. Previous work was performed on terrestrial data and associated simulations representing space debris collisions. The fragmentation of high-velocity fragmentation can be modeled by terrestrial fragmentation tests, such as static detonations. Recently, stereoscopic …
Tricritical Point As A Crossover Between Type-Is And Type-Iis Bifurcations, Prabakaran Rajamanickam, Joel Daou
Tricritical Point As A Crossover Between Type-Is And Type-Iis Bifurcations, Prabakaran Rajamanickam, Joel Daou
Progress in Scale Modeling, an International Journal
A tricritical point as a crossover between (stationary finite-wavelength) type-Is and (stationary longwave) type-IIs bifurcations is identified in the study of diffusive-thermal (Turing) instability of flames propagating in a Hele-Shaw channel in a direction transverse to a shear flow. Three regimes exhibiting different scaling laws are identified in the neighbourhood of the tricritical point. For these three regimes, sixth-order partial differential equations are obtained governing the weakly nonlinear evolution of unstable solutions near the onset of instability. These sixth-order PDES may be regarded as the substitute for the classical fourth-order Kuramoto–Sivashinsky equation which is not applicable near the …
Chacahoula 2023, Tram Phan, Mallory Kaul, Alayna Pellegrin
Chacahoula 2023, Tram Phan, Mallory Kaul, Alayna Pellegrin
Chacahoula
WE GROW, WE DEVELOP, WE THRIVE:
The 2023 issue of Chacahoula includes December 2022 and May 2023 graduating classes, as well as stunning photography of Week of Welcome, Homecoming, Mardi Gras, and Spring Fever. With features covering notable students, faculty, and staff, this year's time capsule beautifully preserves an academic year in the life of the University of Louisiana at Monroe.
Using Noninvasive Calibrated Cuff Plethysmography To Observe The Effects Of Cold-Water Immersion On Arterial Compliance, Rita M. Grigorian
Using Noninvasive Calibrated Cuff Plethysmography To Observe The Effects Of Cold-Water Immersion On Arterial Compliance, Rita M. Grigorian
Master's Theses
As the prevalence of cardiovascular diseases continues to exponentially grow in populations across the globe, the necessity of determining underlying factors, effective methods of diagnoses, and universally available preventive measures also grows. Early detection of endothelial dysfunction, a proven precursor of cardiovascular diseases, can be extremely impactful in encouraging preventative measures and early intervention before medical conditions become chronic. In recent years, ice plunging, a form of cryotherapy involving full body immersion in cold water, has gained popularity within circles of fitness and health practitioners, gaining the interest of people of all backgrounds. Certain parallels observed between the human physiological …
Engineering News, Fall 2023, School Of Engineering
Engineering News, Fall 2023, School Of Engineering
Engineering News
No abstract provided.
Characterization Of Influenza-Specific Antibodies, Xinping Ran
Characterization Of Influenza-Specific Antibodies, Xinping Ran
ENGS 86 Independent Projects (AB Students)
Influenza viruses cause respiratory illness that affects 8% of the U.S. population annually. However, current influenza vaccines have a limited efficacy of only 40-60%. This highlights the need for a universal vaccine design that can generate broadly neutralizing antibodies against influenza surface protein hemagglutinin (HA). Previous work by our group identified HA-specific monoclonal antibodies (mAbs) from serum samples through high-throughput antibody profiling. In this study, three of the identified mAbs were generated using mammalian cell expression and their binding affinity against three HA antigens was characterized via Enzyme-Linked Immuno-Sorbent Assay (ELISA). The ELISA results demonstrated specific binding affinity towards B/Yamagata/18/1998 …