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2018

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Articles 7831 - 7860 of 8951

Full-Text Articles in Engineering

Evaluating E. Coli Particle Attachment And The Impact On Transport During High Flows, Louis Amegbletor Jan 2018

Evaluating E. Coli Particle Attachment And The Impact On Transport During High Flows, Louis Amegbletor

Electronic Theses and Dissertations

Fecal indicator bacteria, including E. coli, are the leading cause of water quality impairments within assessed waters in the United States. The source of E. coli includes WWTP, leaking sewers, animal manure, wildlife, livestock, and stream bed sediment. Storm events contribute to bacteria loading within waters through wash-in of land sources of bacteria and resuspension of bacteria within sediments. Bacteria introduced into the water column are either attached to particles or are unattached (or free-living). The goal of this study was to examine the attachment of E. coli to different particle sizes, including their impact on contributing to water …

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A Scale Space Local Binary Pattern (Sslbp) – Based Feature Extraction Framework To Detect Bones From Knee Mri Scans, Jinyeong Mun Jan 2018

A Scale Space Local Binary Pattern (Sslbp) – Based Feature Extraction Framework To Detect Bones From Knee Mri Scans, Jinyeong Mun

Electronic Theses and Dissertations

The medical industry is currently working on a fully autonomous surgical system, which is considered a novel modality to go beyond technical limitations of conventional surgery. In order to apply an autonomous surgical system to knees, one of the primarily responsible areas for supporting the total weight of human body, accurate segmentation of bones from knee Magnetic Resonance Imaging (MRI) scans plays a crucial role. In this paper, we propose employing the Scale Space Local Binary Pattern (SSLBP) feature extraction, a variant of local binary pattern extractions, for detecting bones from knee images. The proposed methods consist of two phases. …

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Evaluation Of The Effect Of Tack Coat Type, Application Rate, And Surface Type On Interlayer Shear Strength, Chamika Prashan Dharmarathna Jan 2018

Evaluation Of The Effect Of Tack Coat Type, Application Rate, And Surface Type On Interlayer Shear Strength, Chamika Prashan Dharmarathna

Electronic Theses and Dissertations

Tack coat is an asphaltic material applied between asphalt pavement layers. Since pavement is a multilayered structure, it is highly important to make proper bond between the layers to achieve a monolithic behavior. Hence, inadequate bond due to application of inadequate amount of tack coat may lead to poor structural behavior and premature failure. Also, applying excessive amount of tack coat may lead to layer slippage and binder migration. Therefore, it is highly important to apply an optimum amount of tack coat between layers. Over the past decades several studies have been conducted to determine the optimum tack coat application …

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Ca2+/Calmodulin-Dependent Protein Kinase Ii Activity And Expression In The Aged Mouse Hippocampus, James Mitchum Jan 2018

Ca2+/Calmodulin-Dependent Protein Kinase Ii Activity And Expression In The Aged Mouse Hippocampus, James Mitchum

Honors Theses

CaM Kinase II (Ca2+/calmodulin-dependent protein kinase II) is a serine/threonine-specific protein kinase enzyme that acts as a critical regulator of learning and memory. It has previously been shown that the inability of CaMKII to maintain activation is connected to memory deficits within the aging brain. While the connection between CaMKII dysfunction and learning and memory impairments is well established, little is known about the changes that cause CaMKII dysfunction. Our research set out to investigate if CaMKII is altered during the process of aging. Specifically, we looked at activity, regulation, and stability by conducting experiments to quantify CaMKII levels of …

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Onsager Reciprocal Relations: Microscopic (Onsager) Or Macroscopic (Sliepcevich), R. E. "Buddy" Babcock Jan 2018

Onsager Reciprocal Relations: Microscopic (Onsager) Or Macroscopic (Sliepcevich), R. E. "Buddy" Babcock

Chemical Engineering Faculty Publications and Presentations

This paper is a combination of the discussion of two nineteenth century theoretical giants Lars Onsager and C. M. Sliepcevich, their works in general, and specifically the famous reciprocal relations of Onsager with respect to irreversible thermodynamics. Emphasis is placed on their penetrating depth and breadth of analysis so inherently necessary in their problem-solving endeavors. The landscape of their work will be laid out for the reader by a comparison of Onsager’s microscopic statistical mechanics derivation of the famous reciprocal relationships and a macroscopic thermodynamic derivation published by C. M. Sliepsevich that led to considerable discussion in the literature in …

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Biomedical Informatics Applications For Precision Management Of Neurodegenerative Diseases, Justin B. Miller, Guogen Shan, Joseph Lombardo, Gustavo Jimenez-Maggoria Jan 2018

Biomedical Informatics Applications For Precision Management Of Neurodegenerative Diseases, Justin B. Miller, Guogen Shan, Joseph Lombardo, Gustavo Jimenez-Maggoria

School of Public Health Faculty Research

Modern medicine is in the midst of a revolution driven by “big data,” rapidly advancing computing power, and broader integration of technology into healthcare. Highly detailed and individualized profiles of both health and disease states are now possible, including biomarkers, genomic profiles, cognitive and behavioral phenotypes, high-frequency assessments, and medical imaging. Although these data are incredibly complex, they can potentially be used to understand multi-determinant causal relationships, elucidate modifiable factors, and ultimately customize treatments based on individual parameters. Especially for neurodegenerative diseases, where an effective therapeutic agent has yet to be discovered, there remains a critical need for an interdisciplinary …

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Review Of Emerging Approaches In Non- Or Minimally Invasive Glucose Monitoring And Their Application To Physiological Human Body Fluids, Sunghoon Jang, Chen Xu Jan 2018

Review Of Emerging Approaches In Non- Or Minimally Invasive Glucose Monitoring And Their Application To Physiological Human Body Fluids, Sunghoon Jang, Chen Xu

Publications and Research

The frequent blood glucose monitoring by the diabetics and physicians is a very essential step in the management of the diabetes because this devastating disease can lead the patients to blindness, kidney disease, nervous & circulatory system disease, limb amputations, stroke and cardiovascular disease (CVD). There have been numerous attempts to develop viable painless non- or minimally invasive blood glucose monitoring techniques over the last five decades in order to replace all existing methods of home blood glucose monitoring require drawing a blood sample by piercing the skin. This review describes the principles of two main emerging general technologies such …

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Bifurcation-Based Stability Analysis Of Electrostatically Actuated Micromirror As A Two Degrees Of Freedom System, Kuntao Ye, Yan Luo, Yingtao Jiang Jan 2018

Bifurcation-Based Stability Analysis Of Electrostatically Actuated Micromirror As A Two Degrees Of Freedom System, Kuntao Ye, Yan Luo, Yingtao Jiang

Electrical & Computer Engineering Faculty Research

Torsional micromirror devices have been widely used in micro displays, RF switches, optical communications, and optical coherence tomography systems. In order to study the stability of electrostatically driven torsional micromirror system with double bottom plates and two voltage sources, a dimensionless, two degrees of freedom (2-DoF) dynamic model was constructed. Governed by the dimensionless phase space model equation, the pull-in and bifurcation phenomena were analyzed using the Hamiltonian method and numerical simulation. In particular, the influence of the damping coefficient and the torsion-bending coupling effect on the phase trajectory was investigated. Furthermore, the conditions that can lead to pull-in were …

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Unlv Enrollment Analysis, Alexis Acosta, Juan Brena, Chaitanya Ingle, Ajanae' Williams Jan 2018

Unlv Enrollment Analysis, Alexis Acosta, Juan Brena, Chaitanya Ingle, Ajanae' Williams

Math 365 Class Projects

What will be the future enrollment for UNLV between 2021 to 2025? What will be the future enrollment for the College of Engineering between 2021 and 2025?

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Thickness Dependence Of Electrical Conductivity In A Thin Film Thermoelectric Composite, David Zagaceta, William Rogers, Andres Breucop, Brian Herrera Jan 2018

Thickness Dependence Of Electrical Conductivity In A Thin Film Thermoelectric Composite, David Zagaceta, William Rogers, Andres Breucop, Brian Herrera

Math 365 Class Projects

In this work we utilize the Van Der Pauw method for measuring and calculating the electrical conductivity of a composite material in relation to its thickness.

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Climate Change And Eutrophication: A Short Review, Mohammad Nazari-Sharabian, Sajjad Ahmad, Moses Karakouzian Jan 2018

Climate Change And Eutrophication: A Short Review, Mohammad Nazari-Sharabian, Sajjad Ahmad, Moses Karakouzian

Civil and Environmental Engineering and Construction Faculty Research

Water resources are vital not only for human beings but essentially all ecosystems. Human health is at risk if clean drinking water becomes contaminated. Water is also essential for agriculture, manufacturing, energy production and other diverse uses. Therefore, a changing climate and its potential effects put more pressure on water resources. Climate change may cause increased water demand as a result of rising temperatures and evaporation while decreasing water availability. On the other hand, extreme events as a result of climate change can increase surface runoff and flooding, deteriorating water quality as well. One effect is water eutrophication, which occurs …

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Shape From Focus Image Processing Approach Based 3d Model Construction Of Manufactured Part, Mitchel Wendland Jan 2018

Shape From Focus Image Processing Approach Based 3d Model Construction Of Manufactured Part, Mitchel Wendland

University of the Pacific Theses and Dissertations

The purpose of this research is to develop a process and an algorithm to create a 3D model of the surface a part. This is accomplished using a single camera and a CNC machine as a movable stage. A gradient based focus measure operator written in MATLAB is used to process the images and to generate the surface model. The scopes of this research are image processing and surface model generation as well as verifying part accuracy. The algorithm is able to create a rough surface model of a photographed part, and with careful calibration in a limited number of …

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Study On Electrolyte-Gated Graphene Nanoelectronic Biosensors For Biomarker Detection, Jianbo Sun Jan 2018

Study On Electrolyte-Gated Graphene Nanoelectronic Biosensors For Biomarker Detection, Jianbo Sun

Graduate Theses, Dissertations, and Problem Reports (ETD)

Biosensors are called upon to provide valuable benefits for human society in vital fields such as disease diagnosis, food inspection, environment monitoring, etc. Among the various biosensor architectures, the field effect transistor (FET) biosensors are promising as the next generation nanoelectronic biosensors, particularly attractive for point-of-care biomedical applications. The FET biosensors typically operate by measuring the conductance change of the semiconducting channel induced by the adsorption of the target biomolecules on it. The superior properties of graphene, including the unique electronic characteristics, facile functionalization and good biocompatibility, etc., make it an ideal building block for the FET biosensors. In this …

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The Pattern Of Sensory Axonal Endings Together With Synaptic Transmission Influence The Development Of Proprioceptive Circuits In The Spinal Cord, Yiyun Dai Jan 2018

The Pattern Of Sensory Axonal Endings Together With Synaptic Transmission Influence The Development Of Proprioceptive Circuits In The Spinal Cord, Yiyun Dai

Browse all Theses and Dissertations

Proprioceptive circuits provide information regarding limb position and movement status, and are essential to producing correctly executed motor behaviors. Exploring the mechanisms underlying the formation of proprioceptive circuits is therefore critical for understanding neurological disorders with altered motor coordination and for restoring circuits damaged by injury. One important proprioceptive circuit, the stretch reflex circuit, is formed between proprioceptive sensory neurons (PSNs) and motor neurons (MNs) that innervate the same muscle. Progress has been made in understanding the spatial organization of MNs based on their muscle-specific subpopulation identities, which contributes to the specificity of stretch reflex circuit formation. However, whether PSNs …

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Electroceutical Therapy In Amyotrophic Lateral Sclerosis: A Novel Preliminary Study, Morgan Michelle Highlander Jan 2018

Electroceutical Therapy In Amyotrophic Lateral Sclerosis: A Novel Preliminary Study, Morgan Michelle Highlander

Browse all Theses and Dissertations

Amyotrophic Lateral Sclerosis (ALS) is a fatal, neurodegenerative disease that is characterized by the death of motoneurons. Life expectancy is only 3-5 years from diagnosis and current treatments only extend survival by 2-3 months. The mechanism of motoneuron death in ALS is still largely unknown, but abnormal motoneuron excitability has been extensively documented. Because the intrinsic excitability of a motoneuron is a defining measure of its normal function, characterizing and regulating motoneuron excitability has become one of the primary aims of ALS research. Although not previously explored in ALS, other clinical applications show the ability of certain electroceutical techniques to …

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Regulation Of The Motor Output Of The Spinal Cord: Burst Firing Generation And Sensorimotor Integration, Amr A. Mahrous Jan 2018

Regulation Of The Motor Output Of The Spinal Cord: Burst Firing Generation And Sensorimotor Integration, Amr A. Mahrous

Browse all Theses and Dissertations

Spinal motoneurons are the final common path for motor signals. Thus, the firing activity recorded from spinal motoneurons or their axons in the ventral roots represents the motor output of the nervous system. This dissertation investigates two major phenomena that help generate and shape the neuronal motor output. Specialized groups of spinal neurons called central pattern generators (CPGs) are capable of orchestrating rhythmic bursting activity without involvement of the brain. This activity underlies stereotyped movements such as locomotion. If known, the ionic mechanisms responsible for generating this activity can offer new pharmacological interventions to restore walking in paralyzed patients with …

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Consequences Of Trpm7 Kinase Inactivation In Immune Cells, Pavani Beesetty Jan 2018

Consequences Of Trpm7 Kinase Inactivation In Immune Cells, Pavani Beesetty

Browse all Theses and Dissertations

The characteristic feature of ubiquitously expressed transient receptor potential melastatin 7 (TRPM7) protein is the presence of a C-terminal atypical kinase domain fused to a cation channel domain. Even though this protein has been implicated in a number of physiological and pathological processes, the mechanisms regulating TRPM7 channel activity are poorly understood. In the present study, regulation of TRPM7 channel by its kinase activity was investigated using the TRPM7 kinase-dead knock-in mouse (KD mouse). These mice have a point mutation Lys1646Arg in the kinase region abrogating the kinase activity. Examining TRPM7 channel activity in KD peritoneal macrophages revealed that TRPM7 …

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Steady-State And Small-Signal Modeling Of A-Source Converter, Agasthya Ayachit Jan 2018

Steady-State And Small-Signal Modeling Of A-Source Converter, Agasthya Ayachit

Browse all Theses and Dissertations

As the trend towards vehicle electrification, renewable energy, smart systems is increasing, the key enabling technology such as power electronics are becoming ever more important. Power electronics is the vital component of many applications in automotive, computer, data-centers, medical, aerospace, communication, green-energy, and manufacturing sectors. Major advancements in high efficiency, high power density, high voltage conversion ratio, and fast dynamic response power-electronic converters is evident both in research and industry, particularly at the topology level. A major contribution of this dissertation is the analysis, design, development, and dynamic modeling of a novel impedance-source topology termed as A-source converter, which potentially …

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Characterization And Design Of Voltage-Mode Controlled Full-Bridge Dc/Dc Converter With Current Limit, Nathaniel R. Smith Jan 2018

Characterization And Design Of Voltage-Mode Controlled Full-Bridge Dc/Dc Converter With Current Limit, Nathaniel R. Smith

Browse all Theses and Dissertations

Advancements in Direct Current (DC) electrical power systems have enabled new functionality in many, varied applications. Discrete power semiconductor devices are increasing in efficiency, switching frequency, and power density, resulting in greater usage of DC power management and distribution methods, including DC/DC conversion. DC distribution lacks inherent capability to safely and effectively break fault current, particularly in mobile solutions, where larger and slower electromechanical switching devices are not optimal or feasible. One solution is to design a low-energy breaking point into a switching power supply. Simpler converter designs, with a lower number of switching devices, have been modeled and can …

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Effect Of Process Parameters On The Surface Roughness And Mechanical Performance Of Additively Manufactured Alloy 718, Bo Ryan Whip Jan 2018

Effect Of Process Parameters On The Surface Roughness And Mechanical Performance Of Additively Manufactured Alloy 718, Bo Ryan Whip

Browse all Theses and Dissertations

Metal additive manufacturing (AM) is a method to create complex components in a layer-by-layer process. Currently, there is a lack of understanding in the processing-structure-properties-performance relationship, particularly related to defects inherent to the AM process. This work investigates the relationship of process parameters, as-built surface roughness, and mechanical performance for nickel-based superalloy 718 built using laser powder bed fusion. The surface roughness of components built using varied processing parameters was characterized using both nondestructive and destructive measurement techniques. Finite element analysis was used to study the stress concentration on surface profiles. Statistical correlations are presented between contour processing parameters and …

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Effect Of Pyrolysis On The Removal Of Antibiotic Resistance Genes And Class I Integrons From Municipal Wastewater Biosolids, Lee Kimbell, Anthony D. Kappell, Patrick J. Mcnamara Jan 2018

Effect Of Pyrolysis On The Removal Of Antibiotic Resistance Genes And Class I Integrons From Municipal Wastewater Biosolids, Lee Kimbell, Anthony D. Kappell, Patrick J. Mcnamara

Civil and Environmental Engineering Faculty Research and Publications

Wastewater biosolids represent a significant reservoir of antibiotic resistance genes (ARGs). While current biosolids treatment technologies can reduce ARG levels in residual wastewater biosolids, observed removal rates vary substantially. Pyrolysis is an anoxic thermal degradation process that can be used to convert biosolids into energy rich products including py-gas and py-oil, and a beneficial soil amendment, biochar. Batch pyrolysis experiments conducted on municipal biosolids revealed that the 16S rRNA gene, the ARGs erm(B), sul1, tet(L), tet(O), and the integrase gene of class 1 integrons (intI1) were significantly reduced at pyrolysis temperatures ranging from 300–700 …

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Construction Engineering Education Committee: Past, Present, And Future, Yong Bai Jan 2018

Construction Engineering Education Committee: Past, Present, And Future, Yong Bai

Civil and Environmental Engineering Faculty Research and Publications

No abstract provided.

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Amplifying The Social Intelligence Of Teams Through Human Swarming, Louis Rosenberg, Gregg Willcox, David Askay, Lynn Metcalf Jan 2018

Amplifying The Social Intelligence Of Teams Through Human Swarming, Louis Rosenberg, Gregg Willcox, David Askay, Lynn Metcalf

Industrial Technology and Packaging

Artificial Swarm Intelligence (ASI) is a method for amplifying the collective intelligence of human groups by connecting networked participants into real-time systems modeled after natural swarms and moderated by AI algorithms. ASI has been shown to amplify performance in a wide range of tasks, from forecasting financial markets to prioritizing conflicting objectives. This study explores the ability of ASI systems to amplify the social intelligence of small teams. A set of 61 teams, each of 3 to 6 members, was administered a standard social sensitivity test —"Reading the Mind in the Eyes” or RME. Subjects took the test both as …

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Investigation Of Compression Strength Of Bliss Style Corrugated Fiberboard Boxes, Javier De La Fuente, Jay Singh, Rebecca Kisch, Soma Roy, Daan Peleman Jan 2018

Investigation Of Compression Strength Of Bliss Style Corrugated Fiberboard Boxes, Javier De La Fuente, Jay Singh, Rebecca Kisch, Soma Roy, Daan Peleman

Industrial Technology and Packaging

The global demand for corrugated fiberboard is projected to experience a significant upsurge in the near future. Based on the end-use, packaging for processed and fresh food categories accounted for approximately 39% of the overall consumption of corrugated fiberboard in 2015. With key advantages such as providing an uninterrupted bottom, laminated corners for higher stacking strength, increased material use efficiency, side cutout options for display at retail and a wide range of styles over other styles of containers, Bliss style boxes find prominence in the agriculture sector. While numerous predictive strength models associating corrugated fiberboard material specifications to the box …

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Case Study: Applying Lean Manufacturing Principles To The Prep Process Of The Hurricane Island Outward Bound School, Ben Branson Jan 2018

Case Study: Applying Lean Manufacturing Principles To The Prep Process Of The Hurricane Island Outward Bound School, Ben Branson

Honors Theses

This study synthesizes the author's area of education and occupational passions by applying lean manufacturing principles such as those of the Toyota Production System to the course preparation process at the Hurricane Island Outward Bound School. Over four weeks in the summer of 2017, the initial conditions were monitored and changes were implemented in both the layout of the base and the process itself, specifically the logistics portions. At the end of the season, the effectiveness of these changes were evaluated through a staff survey and comparison of evidence gathered during the summer. The time needed for prep logistics was …

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Design And Production Of A Um Photo Album, Daniel Kennedy, David Johnson Jan 2018

Design And Production Of A Um Photo Album, Daniel Kennedy, David Johnson

Honors Theses

The authors would like to thank all the CME faculty and staff that made this project possible. Without their commitment to the students and the program, projects like this one would never make if off the ground. The authors would like to extend special thanks to Richard Hairston who served as a technical advisor for the project. Special thanks also the CME professors Dr. Vaughn, Dr. McClurg, and Ms. Watanabe. Their guidance was invaluable when the team found itself deep in the weeds. Lastly the authors would like to thank their amazing team that made this idea come to life. …

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A Study Of The Product Development Process For The Stackable Shelf, Stool, And Table, Harleigh Elizabeth Huggins Jan 2018

A Study Of The Product Development Process For The Stackable Shelf, Stool, And Table, Harleigh Elizabeth Huggins

Honors Theses

The purpose of this project was to create a viable furniture product by utilizing the various phases of the product development process. The project began in Phase 0 with market research, formulation of an initial idea, and a product pitch to an executive board to check the viability of the idea. Then, the idea was developed into a concept with Phase 1 by finalizing an initial concept and looking into the potential customer. Next, the product concept was prototyped through several iterations of trial and error in Phase 2. By Phase 3, the product design was finalized, and an initial …

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Design And Analysis Of An Fmri-Compatible Vibrotactile Skin Stimulator, Jacob Skyler Azbell Jan 2018

Design And Analysis Of An Fmri-Compatible Vibrotactile Skin Stimulator, Jacob Skyler Azbell

Honors Theses

The purpose of this research project is to design a multi-purpose fMRI-compatible vibrotactile skin stimulator that can be used in varying felds of research so that a specifc design does not have to be built for each individual application. Throughout this project, several stimulator designs were produced, but the core idea for each was quite similar. In each design, a wire coil was wound on a exible plastic tape former. One point of each coil is fxed, and the opposite point provides stimulation. Each wire coil was placed in a constant magnetic feld, which provided a weaker version of the …

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Design And Synthesis Of Novel Cannabinoid Receptor Modulators, Mary Paige Thrash Jan 2018

Design And Synthesis Of Novel Cannabinoid Receptor Modulators, Mary Paige Thrash

Honors Theses

Cannabinoid (CB) receptors are validated drug targets in the endocannabinoid signaling system associated with a number of human pathologies, and the development of novel and selective small molecule CB ligands is warranted. A lead molecule HL-010, a member of the 4H-thieno[3,2-b]pyrrole-5-carboxamide class of compounds, was previously identified through CB homology modeling and virtual screening protocols as a potential high affinity ligand for cannabinoid receptors. Validation of the in silico data was realized with the evaluation of both CB1 and CB2 receptor binding and functional activity assessment: HL-010 was found to be a potent (~10 nM) and selective CB2 receptor agonist …

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Cardiolipin Profiling In Metastatic Breast Cancer Cells, Meghan Houston Mcneely Jan 2018

Cardiolipin Profiling In Metastatic Breast Cancer Cells, Meghan Houston Mcneely

Honors Theses

Six human breast cancer cell lines (MDA-MB-231, LM, BoM, T47D, MCF7, and MCF7-BoM) were treated with three differentially targeted phospholipase inhibitors (bromoenol lactone, tricyclodecan-9-yl-xanthogenate, and halopemide) as well as various dietary oils (canola oil, avocado oil, coconut oil, olive oil, sesame oil, and soybean oil). Cell viability assays were performed to examine the effects of each inhibitor and oil in varying concentrations on the proliferation of each breast cancer cell line. The goal was to detect changes in cardiolipin concentration within each cell line after exposure to a series of various phospholipase inhibitors and oils. Liquid chromatography-mass spectrometry (LC-MS) was …

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