Engineering Commons^™

Effect Of Nitrogen On Properties Of Na2o-Cao-Sro-Zno-Sio2 Glasses, Ahmed Bachar, Cyrille Mercier, Arnaud Tricoteaux, Jean Christophe Hornez, Anne Leriche, Claudine Follet, Bertrand Revel, Stuart Hampshire, Mark R. Towler

Chemical and Biochemical Engineering Faculty Research & Creative Works

Glasses in the Na₂O-CaO-SrO-ZnO-SiO₂ system have previously been investigated for suitability as a reagent in Al-free glass polyalkenoate cements (GPCs). These materials have many properties that offer potential in orthopedics. However, their applicability has been limited, to date, because of their poor strength. This study was undertaken with the aim of increasing the mechanical properties of a series of these Zn-based GPC glasses by doping with nitrogen to give overall compositions of: 10Na₂O-10CaO-20SrO-20ZnO-(40-3x)SiO₂-xSi₃N₄ (x is the no. of moles of Si₃N₄). The density, glass-transition temperature, hardness, …

Cell Infiltration Into A 3d Electrospun Fiber And Hydrogel Hybrid Scaffold Implanted In The Brain, Christopher J. Rivet, Kun Zhou, Ryan J. Gilbert, David I. Finkelstein, John S. Forsythe

Chemical and Biochemical Engineering Faculty Research & Creative Works

Tissue engineering scaffolds are often designed without appropriate consideration for the translational potential of the material. Solid scaffolds implanted into central nervous system (CNS) tissue to promote regeneration may require tissue resection to accommodate implantation. Or alternatively, the solid scaffold may be cut or shaped to better fit an irregular injury geometry, but some features of the augmented scaffold may fail to integrate with surrounding tissue reducing regeneration potential. To create a biomaterial able to completely fill the irregular geometry of CNS injury and yet still provide sufficient cell migratory cues, an injectable, hybrid scaffold was created to present the …

Astrocytes Increase Atp Exocytosis Mediated Calcium Signaling In Response To Microgroove Structures, Ajay V. Singh, Michael Raymond, Fabiano Pace, Anthony Certo, Jonathan M. Zuidema, Christopher A. Mckay, Ryan J. Gilbert, X. Lucas Lu, Leo Q. Wan

Chemical and Biochemical Engineering Faculty Research & Creative Works

Following central nervous system (CNS) injury, activated astrocytes form glial scars, which inhibit axonal regeneration, leading to long-term functional deficits. Engineered nanoscale scaffolds guide cell growth and enhance regeneration within models of spinal cord injury. However, the effects of micro-/nano size scaffolds on astrocyte function are not well characterized. In this study, a high throughput (HTP) microscale platform was developed to study astrocyte cell behavior on micropatterned surfaces containing 11/4m spacing grooves with a depth of 250 or 500â €...nm. Significant changes in cell and nuclear elongation and alignment on patterned surfaces were observed, compared to on flat surfaces. The …

Development Of Composite Pcms By Incorporation Of Paraffin Into Various Building Materials, Shazim Ali Memon, Wenyu Liao, Shuqing Yang, Hongzhi Cui, Syed Farasat Ali Shah

Civil, Architectural and Environmental Engineering Faculty Research & Creative Works

In this research, we focused on the development of composite phase-change materials (CPCMs) by incorporation of a paraffin through vacuum impregnation in widely used building materials (Kaolin and ground granulated blast-furnace slag (GGBS)). The composite PCMs were characterized using environmental scanning electron microscopy (ESEM), Fourier transform infrared spectroscopy (FT-IR), differential scanning calorimetry (DSC) and thermogravimetric analysis (TGA) techniques. Moreover, thermal performance of cement paste composite PCM panels was evaluated using a self-designed heating system. Test results showed that the maximum percentage of paraffin retained by Kaolin and GGBS was found to be 18% and 9%, respectively. FT-IR results show that …

Evaluation Of Oxidization Of Crumb Rubber-Modified Asphalt During Short-Term Aging, Amir Ghavibazoo, Magdy Abdelrahman, Mohyeldin Ragab

Civil, Architectural and Environmental Engineering Faculty Research & Creative Works

Asphalt binder is subjected to aging during the construction process and service life of pavement. Aging substantially changes the chemical composition and physical properties of asphalt and leads to premature distresses on pavement. It is speculated that crumb rubber modifier (CRM) reduces the susceptibility of asphalt to aging, but its mechanism is not fully understood. Also, the impact of interaction parameters and exchange of components on the aging behavior of a crumb rubber-modified binder is not fully understood. In this study, the effect of CRM on the short-term aging of asphalt was investigated through an analysis of the distinctions between …

Effect Of Used Motor Oil On The Macro And Micromechanical Properties Of Crumb Rubber Modified Asphalt, Magdy Abdelrahman, Mohyeldin Ragab, Daniel Bergerson

Civil, Architectural and Environmental Engineering Faculty Research & Creative Works

The need to be more environmentally conscious has recently shifted toward the forefront of society. With this new focus on environmentally responsible behavior comes the practice of using recycled materials in construction when possible. Used motor oil (UMO) is an example of waste materials that can be utilized in numerous applications to alleviate its environmental disposal burden. In the current work, the effect of UMO on the internal structure of crumb rubber modified asphalt is investigated. This is carried out by employing rheological analysis including dynamic shear rheometer and microindentation testing. Rheological analysis was employed to determine the change in …

Network And Device Forensic Analysis Of Android Social-Messaging Applications, Daniel Walnycky, Ibrahim Baggili, Andrew Marrington, Jason Moore, Frank Breitinger

Electrical & Computer Engineering and Computer Science Faculty Publications

In this research we forensically acquire and analyze the device-stored data and network traffic of 20 popular instant messaging applications for Android. We were able to reconstruct some or the entire message content from 16 of the 20 applications tested, which reflects poorly on the security and privacy measures employed by these applications but may be construed positively for evidence collection purposes by digital forensic practitioners. This work shows which features of these instant messaging applications leave evidentiary traces allowing for suspect data to be reconstructed or partially reconstructed, and whether network forensics or device forensics permits the reconstruction of …

An Empirical Comparison Of Widely Adopted Hash Functions In Digital Forensics: Does The Programming Language And Operating System Make A Difference?, Satyendra Gurjar, Ibrahim Baggili, Frank Breitinger, Alice E. Fischer

Electrical & Computer Engineering and Computer Science Faculty Publications

Hash functions are widespread in computer sciences and have a wide range of applications such as ensuring integrity in cryptographic protocols, structuring database entries (hash tables) or identifying known files in forensic investigations. Besides their cryptographic requirements, a fundamental property of hash functions is efficient and easy computation which is especially important in digital forensics due to the large amount of data that needs to be processed when working on cases. In this paper, we correlate the runtime efficiency of common hashing algorithms (MD5, SHA-family) and their implementation. Our empirical comparison focuses on C-OpenSSL, Python, Ruby, Java on Windows and …

Damage Characteristics In 3d Stitched Composites With Various Stitch Parameters Under In-Plane Tension, Arief Yudhanto, Gilles Lubineau, Isaac Aguilar Ventura, Naoyuki Watanabe, Yutaka Iwahori, Hikaru Hoshi

Mechanical and Aerospace Engineering Faculty Research & Creative Works

Three-dimensional (3D) reinforcement by stitching is effective in improving the impact resistance of composites. Stitching, however, adversely affects the composite's in-plane mechanical responses, and alters its damage mechanisms due to stitch-induced irregularities. We experimentally investigate the effect of two important stitch parameters, stitch density and thread diameter, on the damage characteristics of 3D stitched multidirectional composites under in-plane tension using X-ray radiography, X-ray micro-computed tomography and digital image correlation (DIC). Our study shows that composites stitched with thicker thread exhibit improved tensile strength due to effective hindrance of edge-delamination. We also found that stitch thread affects damage behaviors. A higher …

Electrospray Of An Energetic Ionic Liquid Monopropellant For Multi-Mode Micropropulsion Applications, Steven P. Berg, Joshua L. Rovey, Benjamin D. Prince, Shawn W. Miller, Raymond J. Bemish

Mechanical and Aerospace Engineering Faculty Research & Creative Works

The multi-mode chemical-electric propulsion capable energetic ionic liquid propellant [Emim][EtSO4]-HAN is electro sprayed in a 100 µm capillary emitter to test the electric-mode performance of the propellant. The ionic liquid exhibits stable electrospray emission in both cation and anion extraction modes at a nominal extraction voltage of 3400 V. Near field measurements of current and mass flow rate distribution are taken at flow rates from 0.19 nL/s to 3.06 nL/s. Total emission current, as measured by Faraday cup and integrated, increases from 754 nA to 3195 nA for cation emission and from 552 nA to 2012 nA for anion emission. …

A Collaborative Adaptive Wiener Filter For Multi-Frame Super-Resolution, Khaled M. Mohamed, Russell C. Hardie

Electrical and Computer Engineering Faculty Publications

Factors that can limit the effective resolution of an imaging system may include aliasing from under-sampling, blur from the optics and external factors, and sensor noise. Image restoration and super-resolution (SR) techniques can be used to improve image resolution. One SR method, developed recently, is the adaptive Wiener filter (AWF) SR algorithm. This is a multi-frame SR method that combines registered temporal frames through a joint nonuniform interpolation and restoration process to provide a high-resolution image estimate. Variations of this method have been demonstrated to be effective for multi-frame SR, as well demosaicing RGB and polarimetric imagery. While the AWF …

Robust Super-Resolution By Fusion Of Interpolated Frames For Color And Grayscale Images, Barry K. Karch, Russell C. Hardie

Electrical and Computer Engineering Faculty Publications

Multi-frame super-resolution (SR) processing seeks to overcome undersampling issues that can lead to undesirable aliasing artifacts in imaging systems. A key factor in effective multi-frame SR is accurate subpixel inter-frame registration. Accurate registration is more difficult when frame-to-frame motion does not contain simple global translation and includes locally moving scene objects. SR processing is further complicated when the camera captures full color by using a Bayer color filter array (CFA). Various aspects of these SR challenges have been previously investigated. Fast SR algorithms tend to have difficulty accommodating complex motion and CFA sensors. Furthermore, methods that can tolerate these complexities …

Ventilation Rates And Airflow Pathways In Patient Rooms: A Case Study Of Bioaerosol Containment And Removal, Ehsan S. Mousavi, Kevin R. Grosskopf

Durham School of Architectural Engineering and Construction: Faculty Publications

Most studies on the transmission of infectious airborne disease have focused on patient room air changes per hour (ACH) and how ACH provides pathogen dilution and removal. The logical but mostly unproven premise is that greater air change rates reduce the concentration of infectious particles and thus, the probability of airborne disease transmission. Recently, a growing body of research suggests pathways between pathogenic source (patient) and control (exhaust) may be the dominant environmental factor. While increases in airborne disease transmission have been associated with ventilation rates below 2 ACH, comparatively less data are available to quantify the benefits of higher …

Adaptive Predictive Functional Controller, Fadi Alsaleem, Arvind Rao

Durham School of Architectural Engineering and Construction: Faculty Publications

A controller device and a method for controlling a system that utilizes an adaptive mechanism to self-learn the system char acteristics and incorporates this adaptive self-learning ability to predict a control parameter correctly to provide precise control of a system component.

An Adaptive Photovoltaic Topology To Overcome Shading Effect In Pv Systems, Mohamed Amer Chaaban, Lana El Chaar, Mahmoud Alahmad

Durham School of Architectural Engineering and Construction: Faculty Publications

Shading in photovoltaic systems can cause many undesired effects.When shading occurs, the power generated from the PV system is much less than nominal power, increasing the electrical mismatching losses between PV system components. Active research to address this power loss focuses on static and adaptive systems.This paper addresses an adaptive system solution and proposes a new method to adaptively overcome losses due to shading during low radiation conditions. In addition, a statistical analysis for choosing the most feasible and efficient configuration for the system size is presented. The proposed system has been validated under shade conditions in a simulation and …

Building Envelope And Interior Grading Systems And Methods, Fadi Mohammad Alsaleem

Durham School of Architectural Engineering and Construction: Faculty Publications

A difference module determines differences between an out door ambient temperature and an indoor temperature, deter mines a first average of the differences, and determines a second average of the differences. A storing module stores a first data point, the first data point including the first average and a first total run time of a heating, ventilation, and/or air conditioning (HVAC) system, and stores a second data point, the second data point including the second average and a second total run time of the HVAC system. A fitting module fits a line to the first and second data points. An …

From The Desk Of The Editor

Journal of International Technology and Information Management

No abstract provided.

Design And Optimization Of Nanoplasmonic Waveguide Devices, Pouya Dastmalchi

LSU Doctoral Dissertations

In this dissertation, we introduce compact absorption switches consisting of plasmonic metal-dielectric-metal (MDM) waveguides coupled to multisection cavities. The optimized multisection cavity switches lead to greatly enhanced modulation depth compared to optimized conventional Fabry-Perot cavity switches. We find that the modulation depth of the optimized multisection cavity switches is greatly enhanced compared to the optimized conventional Fabry-Perot cavity switches due to the great enhancement of the total electromagnetic field energy in the cavity region. We then investigate how to improve the computational efficiency of the design of nanoplasmonic devices. More specifically, we show that the space mapping algorithm, originally developed …

Electroporation Of Mammalian Cells By Nanosecond Electric Field Oscillations And It's Inhibition By The Electric Field Reversal, Elena C. Gianulis, Jimo Lee, Chunqi Jiang, Shu Xiao, Bennet L. Ibey, Andrei G. Pakhomov

Bioelectrics Publications

The present study compared electroporation efficiency of bipolar and unipolar nanosecond electric field oscillations (NEFO). Bipolar NEFO was a damped sine wave with 140 ns first phase duration at 50% height; the peak amplitude of phases 2-4 decreased to 35%, 12%, and 7% of the first phase. This waveform was rectified to produce unipolar NEFO by cutting off phases 2 and 4. Membrane permeabilization was quantified in CHO and GH₃ cells by uptake of a membrane integrity marker dye YO-PRO-1 (YP) and by the membrane conductance increase measured by patch clamp. For treatments with 1-20 unipolar NEFO, at 9.6-24 …

In Situ Oh Generation From O2- And H2o2 Plays A Critical Role In Plasma Induced Cell Death, Dehui Xu, Dingxing Liu, Biqing Wang, Chen Chen, Zeyu Chen, Dong Li, Yanjie Yang, Hailan Chen, Michael G. Kong

Bioelectrics Publications

Reactive oxygen and nitrogen species produced by cold atmospheric plasma (CAP) are considered to be the most important species for biomedical applications, including cancer treatment. However, it is not known which species exert the greatest biological effects, and the nature of their interactions with tumor cells remains ill-defined. These questions were addressed in the present study by exposing human mesenchymal stromal and LP-1 cells to reactive oxygen and nitrogen species produced by CAP and evaluating cell viability. Superoxide anion (O₂-) and hydrogen peroxide (H₂O₂) were the two major species present in plasma, but their …

Ablation Of Myocardial Tissue With Nanosecond Pulsed Electric Fields, Fei Xie, Frency Varghese, Andrei G. Pakhomov, Iurii Semenov, Shu Xiao, Jonathan Philpott, Christian Zemlin

Bioelectrics Publications

Background

Ablation of cardiac tissue is an essential tool for the treatment of arrhythmias, particularly of atrial fibrillation, atrial flutter, and ventricular tachycardia. Current ablation technologies suffer from substantial recurrence rates, thermal side effects, and long procedure times. We demonstrate that ablation with nanosecond pulsed electric fields (nsPEFs) can potentially overcome these limitations.

Methods

We used optical mapping to monitor electrical activity in Langendorff-perfused New Zealand rabbit hearts (n = 12). We repeatedly inserted two shock electrodes, spaced 2–4 mm apart, into the ventricles (through the entire wall) and applied nanosecond pulsed electric fields (nsPEF) (5–20 kV/cm, 350 ns duration, …

Effects Of Nanosecond Pulse Electric Fields On Cellular Elasticity, Diganta Dutta, Anthony Asmar, Michael W. Stacey

Bioelectrics Publications

We investigated the effects of a single 60 nanosecond pulsed electric field (nsPEF) of low (15 kV/cm) and high (60 kV/cm) field strengths on cellular morphology and membrane elasticity in Jurkat cells using fluorescent microscopy and atomic force microscopy (AFM). We performed force displacement measurements on cells using AFM and calculated the Young's modulus for membrane elasticity. Differential effects were observed depending upon pulsing conditions. We found that a single nsPEF of low field strength did not induce any apparent cytoskeletal breakdown and had minor morphological changes. Interestingly, force measurements and calculation of Young's modulus showed a significant decrease in …

Possible Effects Of Nanosecond Pulsed Electric Fields On Proteins, Stephen J. Beebe

Bioelectrics Publications

No abstract provided.

Microbubble Generation By Piezotransducer For Biological Studies, W. Zhu, M. Alkhazal, M. Cho, S. Xiao

Bioelectrics Publications

Bubbles induced by blast waves or shocks are speculated to be the major cause of damages in biological cells in mild traumatic brain injuries. Microbubble collapse was found to induce noticeable cell detachment from the cell substrate, changes in focal adhesion and biomechanics. To better understand the bubble mechanism, we would like to construct a system, which allows us to clearly differentiate the impact of bubbles from that of shocks. Such a generator needs to be low profile in order to place under a microscope. A piezoelectric transducer system was designed to meet the need. The system uses either a …

Cell Stimulation And Calcium Mobilization By Picosecond Electric Pulses, Iurii Semenov, Shu Xiao, Dongkoo Kang, Karl H. Schoenbach, Andrei G. Pakhomov

Bioelectrics Publications

We tested if picosecond electric pulses (psEP; 190 kV/cm, 500 ps at 50% height), which are much shorter than channel activation time, can activate voltage-gated (VG) channels. Cytosolic Ca²⁺ was monitored by Fura-2 ratiometric imaging in GH3 and NG108 cells (which express multiple types of VG calcium channels, VGCC), and in CHO cells (which express no VGCC). Trains of up to 100 psEP at 1 kHz elicited no response in CHO cells. However, even a single psEP significantly increased Ca²⁺ in both GH3 (by 114 +/- 48 nM) and NG108 cells (by 6 +/- 1.1 nM). Trains of …

Diffuse, Non-Polar Electropermeabilization And Reduced Propidium Uptake Distinguish The Effect Of Nanosecond Electric Pulses, Iurii Semenov, Christian W. Zemlin, Olga N. Pakhomova, Shu Xiao, Andrei G. Pakhomov

Bioelectrics Publications

Ca²⁺ activation and membrane electroporation by 10-ns and 4-ms electric pulses (nsEP and msEP) were compared in rat embryonic cardiomyocytes. The lowest electric field which triggered Ca²⁺ transients was expectedly higher for nsEP (36 kV/cm)than forms EP (0.09 kV/cm) but the respective doses were similar (190 and460 mJ/g). At higher intensities, both stimuli triggered prolonged firing in quiescent cells. An increase of basal Ca²⁺ level by N10 nM in cells with blocked voltage-gated Ca²⁺ channels and depleted Ca²⁺ depot occurred at 63 kV/cm (nsEP) or 0.14 kV/cm (msEP) and was regarded as electroporation threshold. These …

Relevance Of Blood Vessel Networks In Blast-Induced Traumatic Brain Injury, Yi Hua, Shengmao Lin, Linxia Gu

Department of Mechanical and Materials Engineering: Faculty Publications

Cerebral vasculature is a complex network that circulates blood through the brain. However, the role of this networking effect in brain dynamics has seldom been inspected. This work is to study the effects of blood vessel networks on dynamic responses of the brain under blast loading. Voronoi tessellations were implemented to represent the network of blood vessels in the brain. The brain dynamics in terms of maximumprincipal strain (MPS), shear strain (SS), and intracranial pressure (ICP) weremonitored and compared. Results show that blood vessel networks significantly affected brain responses.The increased MPS and SS were observed within the brain embedded with …

In Situ Longitudinal Pre-Stretch In The Human Femoropopliteal Artery, Alexey Kamenskiy, Andreas Seas, Grant Bowen, Paul Deegan, Anastasia Desyatova, Nick Bohlim, William Poulson, Jason N. Mactaggart

Department of Mechanical and Materials Engineering: Faculty Publications

In situ longitudinal (axial) pre-stretch (LPS) plays a fundamental role in the mechanics of the femoropopliteal artery (FPA). It conserves energy during pulsation and prevents buckling of the artery during limb movement. We investigated how LPS is affected by demographics and risk factors, and how these patient characteristics associate with the structural and physiologic features of the FPA. LPS was measured in n=148 fresh human FPAs (14–80 years old). Mechanical properties were characterized with biaxial extension and histopathological characteristics were quantified with Verhoeff-Van Gieson Staining. Constitutive modeling was used to calculate physiological stresses and stretches which were then analyzed …

Asphalt Composition, David Allen, Flavio Souza, Yong-Rak Kim, Roberto Soares

Department of Mechanical and Materials Engineering: Faculty Publications

A computational method is provided for predicting roadway failure due to degradation of the roadway over time as a function of the input loads, the roadway geometry, the material properties of the constituents in the asphaltic pavement, the shape, distribution, orientation and volume fractions of the constituents, and environmental conditions. The unique and new feature of the method is that it employs several physically based predictive methodologies simultaneously.

Phase Transformation And Magnetic Properties Of Rapidly Solidified Mn-Al-C Alloys Modified With Zr, Yunlong Geng, Micheal J. Lucis, Pamela Rasmussen, Jeffrey E. Shield

Department of Mechanical and Materials Engineering: Faculty Publications

Mn_54-xAl₄₃C₃Zr_x (x=1, 3) alloys were prepared by rapid solidification followed by heat treatment to produce the ferromagnetic s phase. The substitution of Zr for Mn in the structure resulted in an increase of the saturation magnetization (Ms) compared to that of Mn_54-xAl₄₃C₃. While the highest Ms (12861 emu/g) was obtained in Mn_54-xAl₄₃C₃Zr₁, the coercivity was also improved to 1.62 kOe, compared to 1.25 kOe for Mn_54-xAl₄₃C₃. To further improve the coercivity through grain …