Open Access. Powered by Scholars. Published by Universities.®

Engineering Commons™

Open Access. Powered by Scholars. Published by Universities.®

Theses and Dissertations

Discipline
Institution
Keyword
Publication Year

Articles 5071 - 5100 of 11510

Full-Text Articles in Engineering

On The Microstructural Behavior Of Pure Magnesium Under Various Strain Rates, Peter Malchow Jan 2017

On The Microstructural Behavior Of Pure Magnesium Under Various Strain Rates, Peter Malchow

Theses and Dissertations

An investigation into the localized microstructural response of pure magnesium under both quasi-static and dynamic loading is presented in the form of several experimental works. The meso-scale events were examined using Digital Image Correlation techniques, which provide a methodology for mapping the in-situ full-field material strain behavior.

Firstly, an analysis of the grain boundary activity specifically under dynamic conditions at high magnification is discussed. An area of interest in the region of multiple grain boundaries and triple junctions is selected for characterizing the evolution of the strain and local rotation. This is followed by a study experimentally verifying the causes …


Enhanced Dropwise Condensation Via Wettability Contrast Mechanism, Mohammad Alwazzan Jan 2017

Enhanced Dropwise Condensation Via Wettability Contrast Mechanism, Mohammad Alwazzan

Theses and Dissertations

Condensation heat transfer performance can be improved by many methods including the most common used method, which is by increasing the droplet removal rate of the condensing surface. Commonly, this approached can be achieved by promoting a dropwise condensation mode in which super/hydrophobic coatings can be applied on the entire condenser surface to reduce the surface wettability degree. In this dissertation, two main approaches were adapted to enhance the condensation heat transfer performance of the condensing surface via wettability contrast mechanism. Three approaches of investigation were performed to better understand such dropwise condensation promoter methods.

In the first part, alternative …


Blind Change Point Detection And Regime Segmentation Using Gaussian Process Regression, Sourav Das Jan 2017

Blind Change Point Detection And Regime Segmentation Using Gaussian Process Regression, Sourav Das

Theses and Dissertations

Time-series analysis is used heavily in modeling and forecasting weather, economics, medical data as well as in various other fields. Change point detection (CPD) means finding abrupt changes in the time-series when the statistical property of a certain part of it starts to differ. CPD has attracted a lot of attention in the artificial intelligence, machine learning and data mining communities. In this thesis, a novel CPD algorithm is introduced for segmenting multivariate time-series data. The proposed algorithm is a general pipeline to process any high dimensional multivariate time-series data using nonlinear non-parametric dynamic system. It consists of manifold learning …


Mobile Application For Shipping Goods For Individuals And Truckers In India, Sendurr Selvaraj Jan 2017

Mobile Application For Shipping Goods For Individuals And Truckers In India, Sendurr Selvaraj

Theses and Dissertations

India is a vast country with majority of its cities and towns connected through roads. Road transportation contributes to 86% share of the freight transport of the country with trucking companies dominating the entire space. With growing economy and demands raising, the quality of service of the trucking company remains poor. The major reasons are unorganized practice and lack of transparency. Moreover, limited access for customers to reach out to truckers to transport their goods.

This thesis aims to create a platform for customers and truckers to realize their needs with a help of a mobile application. Customers can search …


Cable Health Monitoring System Built Into Power Converter Using Time Domain Reflectometry, Hossein Baninajar Jan 2017

Cable Health Monitoring System Built Into Power Converter Using Time Domain Reflectometry, Hossein Baninajar

Theses and Dissertations

Aging cables are a critical reliability concern for many electrical systems. Cables run over long distances, are often exposed to harsh environments and are intended to work for several decades. Cable faults can be a serious problem because cables are usually hard to repair or replace. Condition based maintenance is a popular approach that provides high reliability and low maintenance cost at the same time. This is a non-destructive method that collects information about the health condition of the cable under test without causing any potential damage.

Nowadays, in several applications power cables are connected to power converters and it …


Co2 Capture From Flue Gas By A Psa Process Using A Novel Structured Adsorbent, Nima Mohammadi Jan 2017

Co2 Capture From Flue Gas By A Psa Process Using A Novel Structured Adsorbent, Nima Mohammadi

Theses and Dissertations

First adsorption equilibrium isotherms for N2, O2, Ar and CO2 on zeolite 13X were measured at three temperatures (25, 50, 75 °C) and pressures up to 110 kPa with a volumetric method and validated by also measuring the same isotherms with a gravimetric system.

Then a comprehensive 2-D mathematical model was developed to study the fundamentals of adsorption processes in parallel channel structured adsorbents. The results clearly indicated that under studied circumstances the plug flow condition can be assumed and therefore the system is not subject to premature breakthrough.

The pressure drop of corrugated structured adsorbents with narrow triangular channels …


Supercritical Carbon Dioxide Treatment Of Natural Biomaterials For Tissue Engineering Applications, Dominic M. Casali Jan 2017

Supercritical Carbon Dioxide Treatment Of Natural Biomaterials For Tissue Engineering Applications, Dominic M. Casali

Theses and Dissertations

The number of people requiring an organ transplant in the United States has increased considerably over the past 25 years, but the number of organ donations has stagnated; over 8,000 people now die annually while awaiting a transplant or become too sick to receive one. Tissue engineering (TE), the design and production of artificial tissues and organs in vitro, has been proposed to alleviate this problem. Though synthetic polymers offer tunable mechanical and biochemical properties, natural biomaterials have recently garnered attention in TE for their high degree of biocompatibility and ability to direct cell proliferation and constructive tissue remodeling. Yet …


Rational Synthesis Of Catalysts For Biomass Conversion, Qiuli Liu Jan 2017

Rational Synthesis Of Catalysts For Biomass Conversion, Qiuli Liu

Theses and Dissertations

With climate change due to global warming, the production of hydrocarbon fuels and chemicals from renewable biomass resource has become more pressing in recent decades. The biggest challenge in biomass conversion is to develop active, selective and stable catalysts for particular applications. The objective of this research is to optimize catalytic performance for hydrodeoxygenation (HDO) and hydrogenation reactions by enhancing the stability of the support, tuning metal particle size, and controlling surface composition.

The high content of water in bio-oil and the aqueous environment of the upgrading process requires a hydrothermally stable catalyst. The hydrothermal stability has been effectively improved …


Far-Field Optical Microscopy Based On Stimulated Emission Depletion, Yunxia Wang Jan 2017

Far-Field Optical Microscopy Based On Stimulated Emission Depletion, Yunxia Wang

Theses and Dissertations

Conventional lens-based (far-field) fluorescence microscopy is a widely used imaging technique with spatial resolution up to 150–350 nm. However, this technology cannot discern very small structural features, because the spatial resolution is limited by diffraction to about half of the wavelength of light (λ/2,λ is the wavelength of light). Hence, most of the developments in microscopy aim at improving resolution. In the past decades, stimulated emission depletion (STED) microscopy has been developed to bypass the diffraction limit for the application in biological imaging with resolution approaching the nanoscale. The basic principle of STED microscopy is to employ a doughnut-shape laser …


Intermodal Network Design And Expansion For Freight Transportation, Fateme Fotuhiardakani Jan 2017

Intermodal Network Design And Expansion For Freight Transportation, Fateme Fotuhiardakani

Theses and Dissertations

Over the last 50 years, international trade has grown considerably, and this growth has strained the global supply chains and their underlying support infrastructures. Consequently, shippers and receivers have to look for more efficient ways to transport their goods. In recent years, intermodal transport is becoming an increasingly attractive alternative to shippers, and this trend is likely to continue as governmental agencies are considering policies to induce a freight modal shift from road to intermodal to alleviate highway congestion and emissions. Intermodal freight transport involves using more than one mode, and thus, it is a more complex transport process. The …


Experimental And Numerical Investigation Of Pressure Drop In Silicon Carbide Fuel Rod For Application In Pressurized Water Reactors, Ahmed Musafi Abir Jan 2017

Experimental And Numerical Investigation Of Pressure Drop In Silicon Carbide Fuel Rod For Application In Pressurized Water Reactors, Ahmed Musafi Abir

Theses and Dissertations

Spacer grids are used in pressurized water reactors (PWRs) fuel assemblies which enhances heat transfer from fuel rods. However, there remain regions of low turbulence in between the spacer grids which contributes to lower heat transfer. To enhance turbulence in these regions surface roughness is applied on the fuel rod walls. Meyer et al [1] used empirical correlations to predict heat transfer and friction factor for artificially roughened fuel rod bundles at high performance light water reactors (LWRs). At present, several types of materials are being used for fuel rod cladding including zircaloy, uranium oxide, etc. But researchers are actively …


Omni-Directional Infrared 3d Reconstruction And Tracking Of Human Targets, Emrah Benli Jan 2017

Omni-Directional Infrared 3d Reconstruction And Tracking Of Human Targets, Emrah Benli

Theses and Dissertations

Omni-directional (O-D) infrared (IR) vision is an effective capability for mobile systems in robotics, due to its advantages: illumination invariance, wide field-of-view, ease of identifying heat-emitting objects, and long term tracking without interruption. Unfortunately, O-D IR sensors have low resolution, low frame rates, high cost, sensor noise, and an increase in tracking time. In order to overcome these disadvantages, we propose an autonomous system application in indoor scenarios including 1) Dynamic 3D Reconstruction (D3DR) of the target view in real time images, 2) Human Behavior-based Target Tracking from O-D thermal images, 3) Thermal Multisensor Fusion (TMF), and 4) Visual Perception …


Modified Pamam Dendrimers In Tunable Drug-Delivery Systems: A Sustained-Release Dendrimer Hydrogel For Anti-Glaucoma Drugs And Surface-Engineered Macrophages As Nanoparticle Carriers For Targeted Anti-Cancer Therapy, Christopher A. Holden Jan 2017

Modified Pamam Dendrimers In Tunable Drug-Delivery Systems: A Sustained-Release Dendrimer Hydrogel For Anti-Glaucoma Drugs And Surface-Engineered Macrophages As Nanoparticle Carriers For Targeted Anti-Cancer Therapy, Christopher A. Holden

Theses and Dissertations

Two specific drug-delivery applications were sought in this work using polyamidoamine (PAMAM) dendrimers. One drug-delivery system used a novel dendrimer hydrogel (DH) for sustained delivery of anti-glaucoma drugs. In this work, PAMAM G3.0 dendrimers were covalently bonded with poly(ethylene glycol) (PEG­12000) molecules which were subsequently acrylated, resulting in photocurable DH conjugates. For pharmacological studies, DH were loaded with a solution of intraocular pressure lowering drugs, brimonidine and timolol maleate, and were characterized for in vitro release and ex vivo transport and uptake. DH formulations were shown to increase the loading of drug molecules, increase transcorneal drug delivery, and …


Decomposition Algorithms In Stochastic Integer Programming: Applications And Computations., Babak Saleck Pay Jan 2017

Decomposition Algorithms In Stochastic Integer Programming: Applications And Computations., Babak Saleck Pay

Theses and Dissertations

In this dissertation we focus on two main topics. Under the first topic, we develop a new framework for stochastic network interdiction problem to address ambiguity in the defender risk preferences. The second topic is dedicated to computational studies of two-stage stochastic integer programs. More specifically, we consider two cases. First, we develop some solution methods for two-stage stochastic integer programs with continuous recourse; second, we study some computational strategies for two-stage stochastic integer programs with integer recourse. We study a class of stochastic network interdiction problems where the defender has incomplete (ambiguous) preferences. Specifically, we focus on the shortest …


Respiratory Prediction And Image Quality Improvement Of 4d Cone Beam Ct And Mri For Lung Tumor Treatments, Seonyeong Park Jan 2017

Respiratory Prediction And Image Quality Improvement Of 4d Cone Beam Ct And Mri For Lung Tumor Treatments, Seonyeong Park

Theses and Dissertations

Identification of accurate tumor location and shape is highly important in lung cancer radiotherapy, to improve the treatment quality by reducing dose delivery errors. Because a lung tumor moves with the patient's respiration, breathing motion should be correctly analyzed and predicted during the treatment for prevention of tumor miss or undesirable treatment toxicity. Besides, in Image-Guided Radiation Therapy (IGRT), the tumor motion causes difficulties not only in delivering accurate dose, but also in assuring superior quality of imaging techniques such as four-dimensional (4D) Cone Beam Computed Tomography (CBCT) and 4D Magnetic Resonance Imaging (MRI). Specifically, 4D CBCT used in CBCT …


Cooperative Wideband Spectrum Sensing Based On Joint Sparsity, Ghazaleh Jowkar Jan 2017

Cooperative Wideband Spectrum Sensing Based On Joint Sparsity, Ghazaleh Jowkar

Theses and Dissertations

COOPERATIVE WIDEBAND SPECTRUM SENSING BASED ON JOINT SPARSITY

By Ghazaleh Jowkar, Master of Science

A thesis submitted in partial fulfillment of the requirements for the degree of Master of Science at Virginia Commonwealth University

Virginia Commonwealth University 2017

Major Director: Dr. Ruixin Niu, Associate Professor of Department of Electrical and Computer Engineering

In this thesis, the problem of wideband spectrum sensing in cognitive radio (CR) networks using sub-Nyquist sampling and sparse signal processing techniques is investigated. To mitigate multi-path fading, it is assumed that a group of spatially dispersed SUs collaborate for wideband spectrum sensing, to determine whether or not …


Accurate Acoustic Ranging System Using Android Smartphones, Mohammadbagher Fotouhi Jan 2017

Accurate Acoustic Ranging System Using Android Smartphones, Mohammadbagher Fotouhi

Theses and Dissertations

ACCURATE ACOUSTIC RANGING SYSTEM USING ANDROID SMARTPHONES

By Mohammadbagher Fotouhi, Master of Science

A thesis submitted in partial fulfillment of the requirements for the degree of Master of Science at Virginia Commonwealth University

Virginia Commonwealth University 2017

Major Director: Dr. Ruixin Niu, Associate Professor of Department of Electrical and Computer Engineering

In this thesis, we present the design, implementation, and evaluation of an android ranging system, a high-accuracy acoustic-based ranging system which allows two android mobile phones to learn their physical distance from each other.

In this system we propose a practical solution for accurate ranging based on acoustic communication …


A Hierarchical Architectural Framework For Securing Unmanned Aerial Systems, Matthew Leccadito Jan 2017

A Hierarchical Architectural Framework For Securing Unmanned Aerial Systems, Matthew Leccadito

Theses and Dissertations

Unmanned Aerial Systems (UAS) are becoming more widely used in the new era of evolving technology; increasing performance while decreasing size, weight, and cost. A UAS equipped with a Flight Control System (FCS) that can be used to fly semi- or fully-autonomous is a prime example of a Cyber Physical and Safety Critical system. Current Cyber-Physical defenses against malicious attacks are structured around security standards for best practices involving the development of protocols and the digital software implementation. Thus far, few attempts have been made to embed security into the architecture of the system considering security as a holistic problem. …


Coherent/Incoherent Magnetization Dynamics Of Nanomagnetic Devices For Ultra-Low Energy Computing, Md Mamun Al-Rashid Jan 2017

Coherent/Incoherent Magnetization Dynamics Of Nanomagnetic Devices For Ultra-Low Energy Computing, Md Mamun Al-Rashid

Theses and Dissertations

Nanomagnetic computing devices are inherently nonvolatile and show unique transfer characteristics while their switching energy requirements are on par, if not better than state of the art CMOS based devices. These characteristics make them very attractive for both Boolean and non-Boolean computing applications. Among different strategies employed to switch nanomagnetic computing devices e.g. magnetic field, spin transfer torque, spin orbit torque etc., strain induced switching has been shown to be among the most energy efficient. Strain switched nanomagnetic devices are also amenable for non-Boolean computing applications. Such strain mediated magnetization switching, termed here as “Straintronics”, is implemented by switching the …


Development And Validation Of A Novel Resonant Energy Transfer (Fret) Biosensor To Measure Tensile Forces At The Linc Complex In Live Cells, Paul Arsenovic Jan 2017

Development And Validation Of A Novel Resonant Energy Transfer (Fret) Biosensor To Measure Tensile Forces At The Linc Complex In Live Cells, Paul Arsenovic

Theses and Dissertations

There is a large body of evidence supporting the theory that cell physiology largely depends on the mechanical properties of its surroundings or micro-environment. More recently studies have shown that changes to intra-cellular mechanical properties can also have a meaningful impact on cell function and in some cases lead to the progression of ailments or disease. For example, small changes to the protein sequence of a structural nuclear envelope protein called lamin-A is known to cause a variety of neurological and musculoskeletal diseases referred to as laminopathies. Currently, there is little incite into how these mutations lead to disease progression …


Electrospraying Extracellular Matrix To Form Nanoparticles, Patrick Link Jan 2017

Electrospraying Extracellular Matrix To Form Nanoparticles, Patrick Link

Theses and Dissertations

Chronic Obstructive Pulmonary Disease (COPD) is a leading cause of death worldwide. Alveolar wall destruction is a significant contributor to COPD. Inflammatory macrophages are a major source of the Extracellular Matrix (ECM) proteolysis. ECM breakdown causes air to get trapped in the alveoli, obstructing airflow. One step in curing COPD may be to convert inflammatory to pro-regenerative macrophages. Recently, decellularized ECM scaffolds have shown the ability to induce a pro-regenerative phenotype.

Yet these scaffolds are incapable for reaching the alveolar region of the lungs. To reach the alveolar region particles need a diameter of 1-5 μm or smaller than 300 …


Preparation And Application Of Catalysts For The Stereospecific Reduction And Photooxygenation Of Olefins In Continuous Operations: A Novel Method For The Production Of Artemisinin, Daniel C. Fisher Jan 2017

Preparation And Application Of Catalysts For The Stereospecific Reduction And Photooxygenation Of Olefins In Continuous Operations: A Novel Method For The Production Of Artemisinin, Daniel C. Fisher

Theses and Dissertations

Over the last two centuries, the discovery and application of catalysts has had a substantial impact on how and what chemicals are produced.Given their broad significance, our group has focused on developing new catalyst systems that are recoverable and reusable, in an attempt to reduce concomitant costs.

Our efforts have centered on constructing a recyclable chiral heterogeneous catalyst capable of effecting asymmetric hydrogenations of olefins with high stereoselectivity. A class of phosphinoimidazoline ligands, developed by researchers at Boehringer-Ingelheim, known as BIPI ligands, have proven efficacious in the asymmetric reduction of alkenes. However, these chiral ligands are homogeneous and coordinated to …


The Effect Of Vibrotactile Feedback On Remote Manual Task Performance, Matthew S. Standard Jan 2017

The Effect Of Vibrotactile Feedback On Remote Manual Task Performance, Matthew S. Standard

Theses and Dissertations

Vibrotactile feedback offers a unique opportunity to augment or reconstruct impaired tactile sensations, whether that be in the form of enhancing prosthetics or specialized protective clothing. Important information about temperature and object slippage serve to endanger the human operator or equipment. This thesis presents three experiments which investigate amplitude modulated vibrotactile signals as a scalar dimension of roughness, the effect those signals and their locations (finger pad, forearm, bicep) have on the performance of two tasks: the sensing of temperatures simulated by vibrotactile signals and gripping an object of simulated surface texture. The results show task performance increase when the …


A Computational Study Of The Kinematics Of Femoroacetabular Morphology During A Sit-To-Stand Transfer, Brandon K. Marine Jan 2017

A Computational Study Of The Kinematics Of Femoroacetabular Morphology During A Sit-To-Stand Transfer, Brandon K. Marine

Theses and Dissertations

Computational modeling in the field of biomechanics is becoming increasingly popular and successful in practice for its ability to predict function and provide information that would otherwise be unobtainable. Through the application of these new and constantly improving methods, kinematics and joint contact characteristics in pathological conditions of femoroacetabular impingement (FAI) and total hip arthroplasty (THA) were studied using a lower extremity computational model. Patients presenting with FAI exhibit abnormal contact between the femoral neck and acetabular rim leading to surrounding tissue damage in daily use. THA is the replacement of both the proximal femur and acetabular region of the …


Optical Spectroscopy Of Wide Bandgap Semiconductor Heterostructures And Group-Iv Alloy Quantum Dots, Tanner A. Nakagawara Jan 2017

Optical Spectroscopy Of Wide Bandgap Semiconductor Heterostructures And Group-Iv Alloy Quantum Dots, Tanner A. Nakagawara

Theses and Dissertations

Efficient and robust blue InGaN multiple quantum well (MQW) light emitters have become ubiquitous; however, they still have unattained theoretical potential. It is widely accepted that “localization” of carriers due to indium fluctuations theoretically enhance their efficiency by moderating defect-associated nonradiative recombination. To help develop a complete understanding of localization effects on carrier dynamics, this thesis explores degree of localization in InGaN MQWs and its dependence on well thickness and number of wells, through temperature and power dependent photoluminescence measurements. Additionally, silicon-compatible, nontoxic, colloidally synthesizable 2-5 nm Ge1-xSnx alloy quantum-dots (QDs) are explored for potential visible to …


Engineering Icephobic Coatings: Surface Characterization Of Pt Cured Silicones, Sithara Shylaja Nair Jan 2017

Engineering Icephobic Coatings: Surface Characterization Of Pt Cured Silicones, Sithara Shylaja Nair

Theses and Dissertations

Ice buildup on structures leads to problems that include reduced performance, structural damage and power outages. It is therefore important to limit the energy required for removal of ice from substrates to minimize buildup. Understanding the mechanism of ice adhesion and its dependence on variables like coating thickness, stiffness, surface free energy and morphology is critical for minimizing adhesion. Despite several developments in “icephobic” coatings, which are those that have low ice adhesion, it is important to understand adhesion on the fundamental level to make way for advanced coatings. To do so, a study has been carried out that explores …


Low-Temperature Fabrication Process For Integrated High-Aspect Ratio Metal Oxide Nanostructure Semiconductor Gas Sensors, William Paul Clavijo Jan 2017

Low-Temperature Fabrication Process For Integrated High-Aspect Ratio Metal Oxide Nanostructure Semiconductor Gas Sensors, William Paul Clavijo

Theses and Dissertations

This work presents a new low-temperature fabrication process of metal oxide nanostructures that allows high-aspect ratio zinc oxide (ZnO) and titanium dioxide (TiO2) nanowires and nanotubes to be readily integrated with microelectronic devices for sensor applications. This process relies on a new method of forming a close-packed array of self-assembled high-aspect-ratio nanopores in an anodized aluminum oxide (AAO) template in a thin (2.5 µm) aluminum film deposited on a silicon and lithium niobate substrate (LiNbO3). This technique is in sharp contrast to traditional free-standing thick film methods and the use of an integrated thin aluminum film …


Altering A Runner’S Foot Strike Using A Modified Elliptical Trainer, Daniel Shull Jan 2017

Altering A Runner’S Foot Strike Using A Modified Elliptical Trainer, Daniel Shull

Theses and Dissertations

One possible solution to common running related injuries is to transition runners from a rearfoot strike during initial contact to a midfoot strike. Natural rearfoot strike runners were studied to see if a modified elliptical trainer could be used to alter their running pattern to that of a midfoot strike runner. Their results were compared to subjects who ran on a non-modified elliptical trainer. After training on the modified elliptical trainer, subjects demonstrated a decrease in foot angle at initial contact when attempting to run with a midfoot strike. Training did not affect all kinetic metrics or stride frequency. However, …


Nanocomposite Bioelectronics For Biopotential Enabled Prosthesis, Dong Sup Lee Jan 2017

Nanocomposite Bioelectronics For Biopotential Enabled Prosthesis, Dong Sup Lee

Theses and Dissertations

Soft material-enabled electronics can demonstrate extreme mechanical flexibility and stretchability. Such compliant, comfortable electronics allow continuous, long-term measurement of biopotentials on the skin. Manufacturing of the stretchable electronic devices is enabled by the recent development combining materials transfer printing and microfabrication. However, the existing method using inorganic materials and multi-layered polymers requires long material preparation time and expensive processing cost due to the requirement of microfabrication tools and complicated transfer printing steps. Here, this study develops a new fabrication method of soft electronics via a micro-replica-molding technique, which allows fast production, multiple use, and low cost by avoiding microfabrication and …


Parkinson's Symptoms Quantification Using Wearable Sensors, Md Nafiul Alam Jan 2017

Parkinson's Symptoms Quantification Using Wearable Sensors, Md Nafiul Alam

Theses and Dissertations

Parkinson’s disease (PD) is a common neurodegenerative disorder affecting more than one million people in the United States and seven million people worldwide. Motor symptoms such as tremor, slowness of movements, rigidity, postural instability, and gait impairment are commonly observed in PD patients. Currently, Parkinsonian symptoms are usually assessed in clinical settings, where a patient has to complete some predefined motor tasks. Then a physician assigns a score based on the United Parkinson’s Disease Rating Scale (UPDRS) after observing the motor task. However, this procedure suffers from inter subject variability. Also, patients tend to show fewer symptoms during clinical visit, …