Engineering Commons^™

Intravenous Administration Of Iron Oxide Nanoparticles In The Chicken Model, Huong Thi Ngoc Le

Graduate Theses and Dissertations

To be used in health care, the safety and effectiveness of nanoparticles needs to be tested in a living organism. The objective of this project was to develop the chicken as a convenient animal model to examine tissue targeting of intravenously (i.v.)-injected iron oxide (IO) nanoparticles. In Experiment 1, different doses of IO-COOH were i.v. injected into chickens; blood was collected at 0, 5, 15, 30, and 60 minutes post-injection; liver, spleen, lung, and kidney were collected after the last blood collection. For Experiment 2, IO-COOH and IO-PEG were i.v. injected into chickens; blood and the organs were collected at …

Decision Support System For Container Port Selection Using Multiple-Objective Decision Analysis, Rivelino De Icaza

Graduate Theses and Dissertations

Ports are essential for maritime transportation and global supply chains since they are nodes that connect the sea- and land-based modes of transportation. With containerization and supply chains stimulating global trade, ports are challenged to adjust to changes in the market to create value to their customers. Therefore, this dissertation research focuses on the container port selection decision analysis to provide information to help shipping lines select the best port for their shipping networks. Since the problem is complex, dynamic, and involves multiple and conflicting criteria, the research proposes to use the multi-objective decision analysis with Value-Focused Thinking approach. The …

Si-Based Germanium Tin Semiconductor Lasers For Optoelectronic Applications, Sattar H. Sweilim Al-Kabi

Graduate Theses and Dissertations

Silicon-based materials and optoelectronic devices are of great interest as they could be monolithically integrated in the current Si complementary metal-oxide-semiconductor (CMOS) processes. The integration of optoelectronic components on the CMOS platform has long been limited due to the unavailability of Si-based laser sources. A Si-based monolithic laser is highly desirable for full integration of Si photonics chip. In this work, Si-based germanium-tin (GeSn) lasers have been demonstrated as direct bandgap group-IV laser sources. This opens a completely new avenue from the traditional III-V integration approach. In this work, the material and optical properties of GeSn alloys were comprehensively studied. …

Membranes For Food And Bioproduct Processing, Alexandru Marius Avram

Graduate Theses and Dissertations

Modified membranes for process intensification in biomass hydrolysis

Production of biofuels and chemicals from lignocellulosic biomass is one of the leading candidates for replacement of petroleum based fuels and chemicals. However, conversion of lignocellulosic biomass into fuels and chemicals is not cost effective compared to the production of fuels and chemicals from crude oil reserves. Some novel and economically feasible approaches involve the use of ionic liquids as solvents or co-solvents, since these show improved solvation capability of cellulose over simple aqueous systems. Membranes offer unique opportunities for process intensification which involves fractionation of the resulting biomass hydrolysate leading to …

Evaluating One-Step Catalytic Free Method Including Hydrolysis, Esterification, Transesterification, And Degradation Reactions To Produce Biodiesel From Soybean Oil, Mahmood Gheni Jebur

Graduate Theses and Dissertations

Due to the environmental and economic impacts of diesel fuel based on petroleum, several studies have been done to find an alternative source of energy. Biodiesel is considered one of these alternative sources. It is a renewable source of energy produced from vegetable oils and animal fats. There are two main reaction routes used to produce biodiesel (fatty acid methyl esters). Transesterification reaction is the first route used to convert triglycerides to fatty acid methyl esters (FAMEs), while hydrolysis followed by esterification reactions are the second route employed to convert triglycerides to free fatty acids (FFA) and then further converted …

Removal Of Endocrine Disrupting Compounds Using Membrane Bioreactor, Mohanad Ali Abdulsahib Kamaz

Graduate Theses and Dissertations

The presence of endocrine disrupting compounds (EDCs) and pharmaceutically active compounds (PhAC) such as pesticides, personal care products, antibiotics and pharmaceutical compounds, in sewage, industrial, and domestic waters has extensively become the major concern for health and environmental organizations. These compounds have the ability to interact with mammalian endocrine system and disrupting their functions. The traditional activated sludge processes are designed to degrade solids, organic carbon and nitrogen loading. Although several treatment steps in a wastewater treatment plant can contribute to partial removal of EDCs, effective removal has been a challenge due to their resistant chemical and biological degradation and …

Peptide-Directed Nanoparticle Synthesis With A Denovo Pd-Binding Sequence Fused To A Reporter Protein, Rita Eloisa Tejada Vaprio

Graduate Theses and Dissertations

There is a need for low-cost nanoparticle materials in the context of new technologies for catalyst development. The purpose of this work was to recombinantly produce a 45- amino acid long metal binding peptide that is useful for nanoparticle synthesis. Using splicing by overlap extension PCR, a synthetic gene containing the fusion of the metal binding peptide with Green Fluorescent Protein (GFPUV) was constructed. The metal binding peptide, fused to reporter protein GFPUV, was expressed using high cell density fermentation. Palladium nanoparticles of an average diameter of 1.18 0.45 nm were synthesized by using the crude cell extract containing the …

The Effects Of Sprayer Speed And Droplet Size On Herbicide Burndown Efficacy, Justin Carroll

Graduate Theses and Dissertations

An Apache AS1220 self-propelled boom sprayer with a 27.4 m (90 ft) boom was equipped with different sizes (02, 04 and 06) and types (TeeJet AI, XR, AIXR and TTI) of nozzles to achieve medium, very coarse and ultra coarse droplet sizes traveling 11 km/h (7 mph), 19 km/h (12 mph), and 29 km/h (18 mph). These combinations of speed and droplet size were evaluated for percent coverage of the spray and percent control of targeted weeds 3, 7, and 15 days after treatment (DAT). Four replications were conducted for each speed and droplet size combination except for at 19 …

Models And Methodologies To Address Emerging Needs In Network And Supply Chain Optimization, Forough Enayaty Ahangar

Graduate Theses and Dissertations

In this dissertation, we model three different security scenarios and propose solution methodologies to address each problem.

Chapter 2 presents a large-scale optimization approach for solving a dynamic bi-level network interdiction problem (NIP) in which interdiction activities must be scheduled in order to minimize the cumulative maximum flow over a finite time horizon. A logic-based decomposition (LBD) approach is proposed that utilizes constraint programming to exploit the scheduling nature of this dynamic NIP. Chapter 3 considers a set of centers to which content (e.g., data or smuggled items), are assigned to ensure availability. An interdictor (e.g., border security officials) attempts …

Mushroom Inoculation On Switchgrass Feedstock During Storage: Effects Of Subsequent Pre-Processing For Intended Biofuels Production, Amandeep Singh Turay

Graduate Theses and Dissertations

The objective of this project was to examine the effect of fungal treatment and liquid hot water pretreatment of switchgrass combine in view of increasing glucose release. The fungal treatment consisted of incubating Pleurotus ostreatus in square switchgrass bales, at 50% moisture content for 25 days, 54 days, and 82 days. The digestibility of the switchgrass biomass was subsequently evaluated using Accelerase 1500 enzyme. Lignin is an important barrier to enzymatic hydrolysis, and it was stipulated that incubation with P. ostreatus would disrupt plant cell walls, resulting in enhanced saccharification. Three different concentrations of P. ostreatus were evaluated: 0%, 2%, …

Peptoid-Based Microsphere Coatings For Use As Tunable Biocompatible Interfaces, German Raul Perez Bakovic

Graduate Theses and Dissertations

The pursuit of sensitive, non-invasive, and cost efficient diagnostic tools for early stage disease detection have led to the development of sophisticated biosensor technologies for proteomic studies. As these markers increase in complexity, the role of support substrates grows increasingly important. Limitations in existing support substrates include the potential for increased sensitivity, binding specificity, and bio-stability. Ideal support substrates need to provide biocompatible and bioresistant surfaces, that offer high surface areas for binding, and enables the incorporation of diverse chemistries. The use of peptoids as the basis for the deposition of uniform microsphere coatings offers a mean to the attainment …

Personalized Decision Modeling For Intervention And Prevention Of Cancers, Fan Wang

Graduate Theses and Dissertations

Personalized medicine has been utilized in all stages of cancer care in recent years, including the prevention, diagnosis, treatment and follow-up. Since prevention and early intervention are particularly crucial in reducing cancer mortalities, personalizing the corresponding strategies and decisions so as to provide the most appropriate or optimal medical services for different patients can greatly improve the current cancer control practices. This dissertation research performs an in-depth exploration of personalized decision modeling of cancer intervention and prevention problems. We investigate the patient-specific screening and vaccination strategies for breast cancer and the cancers related to human papillomavirus (HPV), representatively. Three popular …

A Low Temperature Co-Fired Ceramic (Ltcc) Interposer Based Three-Dimensional Stacked Wire Bondless Power Module, Atanu Dutta

Graduate Theses and Dissertations

The objective of this dissertation research is to develop a low temperature co-fired ceramic (LTCC) interposer-based module-level 3-D wire bondless stacked power module. As part of the dissertation work, the 3-D wire bondless stack is designed, simulated, fabricated and characterized. The 3-D wire bondless stack is realized with two stand-alone power modules in a half-bridge configuration. Each stand-alone power module consists of two 1200 V 25 A silicon insulated-gate bipolar transistor (IGBT) devices in parallel and two 1200 V 20 A Schottky barrier diodes (SBD) in an antiparallel configuration. A novel interconnection scheme with conductive clamps and a spring loaded …

Experiment-Based Quantitative Modeling For The Antibacterial Activity Of Silver Nanoparticles, Mohammad Aminul Haque

Graduate Theses and Dissertations

Silver (Ag) has been well known for its antimicrobial activity for a long time. Recent research showed the potential of Ag nanoparticles as emerging antimicrobial agents. However, little quantitative analysis has been performed so far to decipher the mechanism of interaction between nanoparticles and bacteria. Here, a detailed analysis based on kinetic growth assay and colony forming unit assay has been carried out to study the antimicrobial effect of Ag nanoparticles against Escherichia coli (E. coli) bacteria. It was observed that the presence of Ag nanoparticles increased the lag time of bacterial growth while not affecting the maximum growth rate …

Simulation Modeling Approach For Evaluating A Solution Designed To Alleviate The Congestion Of Passenger Flow At The Composure Area Of Security Checkpoints, Maria Luisa Janer Rubio

Graduate Theses and Dissertations

In a previous study, we found that replacing the exit roller of a security checkpoint lane for a continuously circulating conveyor could potentially increase the throughput of passengers by over 28% while maintaining the TSA security-waiting time limit (Janer and Rossetti 2016). This study intends to expand this previous effort by investigating the impact of this circulating conveyor on the secondary screening related processes. Leone and Liu (2011) found that imposing a limit on the x-ray screening time, and diverting any item exceeding this limit to secondary screening, could decrease the waiting time by 43%. Our objective is to verify …

Is It We Or They? The Effect Of Identity On Collaboration And Performance In Buyer-Supplier Relationships, Siqi Ma

Graduate Theses and Dissertations

In today’s scale-driven and technology-intensive global economy, collaboration becomes the supply chain’s core capability (Liker and Choi, 2004). A well-developed ability to create and sustain fruitful collaborations gives companies a significant competitive advantage (Kanter, 1994). Retailers are increasingly relying on their suppliers to reduce costs, improve quality, and develop new processes and products faster than their rivals’ vendors can. On the other hand, suppliers benefit from retailers that they are able to monitor store-level demand in real time in order to ensure the top-selling items are in-stock or the accuracy and timeliness of retailer’s demand forecast. Previous literature has shown …

Statistical Movement Classification Based On Hilbert-Huang Transform, Shanqi Sun

Graduate Theses and Dissertations

The goal of this project is to introduce an automatic movement classification technique of

finger movement signals using Hilbert-Huang Transform (HHT). Due to the nonlinear and

nonstationary processing behavior, movement signals are analyzed with the Hilbert-Huang

Transform (HHT). The slope of auto-correlation function and mean of frequency from first

three Intrinsic Mode Functions (IMFs) was used as feature parameters for each category.

Finally, performing support vector machine (SVM) for pattern classification completes clas-

sifying types of finger movement. According to the records of 669 trial samples of two types

of finger movement signals (thumb and pinky), average accuracy is 93.28%. …

Realization Of A High Power Microgrid Based On Voltage Source Converters, Yusi Liu

Graduate Theses and Dissertations

Microgrid concepts are gradually becoming more popular because they are expected to interface with renewable energies, increase end users’ reliability and resiliency, and promote seamless integration of distributed generators (DG) and energy storage units [1]. Most units are connected through power electronics interfaces, such as ac-dc, dc-dc, and dc-ac converters. The converter design and control are critical to the stability and efficiency of a microgrid.

A microgrid may operate in either gird connected mode or islanded mode [1]. In terms of stability, the grid connected mode is less challenging compared to the islanded mode of operation due to the nearly …

Understanding N-Nitrosodimethylamine Formation In Water: Chloramine Chemistry, Kinetics, And A Proposed Reaction Pathway, Huong Thu Pham

Graduate Theses and Dissertations

The formation of N-nitrosodimethylamine (NDMA) in drinking water systems is a concern because of its potential carcinogenicity and occurrence at toxicologically relevant levels. The postulated mechanism for NDMA formation involves a substitution between dichloramine and amine-based precursors to form an unsymmetrical dimethylhydrazine (UDMH), which is then oxidized by ground-state molecular oxygen to form NDMA. However, this latter reaction is spin forbidden, thus likely occurs at a slow rate. It is hypothesized that the reaction between monochloramine and hydroxylamine (a nitrification product) may form an intermediate, which is involved in the NDMA formation pathway. This intermediate may also be generated from …

Computer Simulation Of Pore Migration Due To Temperature Gradients In Nuclear Oxide Fuel, Ian Wayne Vance

Graduate Theses and Dissertations

A phase-field simulation model is being presented that captures the thermal-gradient-driven migration of pores in oxide fuel associated with fuel restructuring. The model utilizes a Cahn-Hilliard equation supplemented with an advection term to describe the vapor transport of fuel material through the pore interior due to gradients in vapor pressure. In addition, the model also captures changes in a migrating pores’ morphology. Simulations demonstrate that the model successfully predicts pore migration towards the hottest portion of the fuel, the centerline. The simulations also demonstrate changes in pore shape that are in agreement with previous experimental observations. Initially isotropic pores are …

Exploring Compaction Effects On Cold In-Place Recycling Mixtures Using Emulsified Asphalt, Erica Ann Yeung

Graduate Theses and Dissertations

Cold in-place recycling (CIR) is a process that takes three to four inches of existing pavement surface and reuses 100% of it by milling and crushing it, adding asphalt emulsions and/or additives to it, before placing and re-compacting it. There is currently very little research regarding the interaction between the crushed aggregate and asphalt emulsion during the CIR process. In this study, the interactions between the combinations of crushed aggregates and asphalt emulsions were investigated along with select compaction metrics and a raveling performance test. The three types of aggregates included coated limestone, recycled asphalt pavement (RAP), and coated syenite. …

Feasibility Of Additive Manufactured Materials For Use In Geotechnical Laboratory Testing Applications, Matthew P. Watters

Graduate Theses and Dissertations

The factors affecting the positive volumetric strain, or dilatancy, typically observed in response to shearing of a dense granular material have long been investigated; however, there still lacks a direct relationship between particle shapes and the resulting dilatant response. The typical Mohr-Coulomb strength parameter associated with granular material is known as the effective friction angle (φ’). For a dense granular assemblage, the peak friction angle has been described as being comprised of a dilatant friction angle (φ’d) component and a critical state friction angle (φ’cv) component. While the topic of dilatancy and factors (both inherent and extrinsic) affecting its behavior …

Characterization Of Plastic Deformation Evolution In Single Crystal And Nanocrystalline Cu During Shock By Atomistic Simulations, Mehrdad Mirzaei Sichani

Graduate Theses and Dissertations

The objective of this dissertation is to characterize the evolution of plastic deformation mechanisms in single crystal and nanocrystalline Cu models during shock by atomistic simulations. Molecular dynamics (MD) simulations are performed for a range of particle velocities from 0.5 to 1.7 km/s and initial temperatures of 5, 300 and 600 K for single crystal models as well as particle velocities from 1.5 to 3.4 km/s for nanocrystalline models with grain diameters of 6, 11, 16 and 26 nm. For single crystal models, four different shock directions are selected, <100>, <110>, <111> and <321>, and dislocation density behind the shock wave …

Total N-Nitrosamine Precursor Adsorption With Carbon Nanotubes: Elucidating Controlling Physiochemical Properties And Developing A Size-Resolved Precursor Surrogate, Erin Needham

Graduate Theses and Dissertations

As drinking water sources become increasingly impaired with nutrients and wastewater treatment plant (WWTP) effluent, formation of disinfection byproducts (DBPs) – such as trihalomethanes (THMs), dihaloacetonitriles (DHANs), and N-nitrosamines – during water treatment may also increase. N-nitrosamines may comprise the bulk of the chronic toxicity in treated drinking waters despite forming at low ng/L levels. This research seeks to elucidate physicochemical properties of carbon nanotubes (CNTs) for removal of DBP precursors, with an emphasis on total N-nitrosamines (TONO).

Batch experiments with CNTs were completed to assess adsorption of THM, DHAN, and TONO precursors; physiochemical properties of CNTs were quantified through …

Development Of A Multiband Remote Sensing System For Determination Of Unsaturated Soil Properties, Cyrus D. Garner

Graduate Theses and Dissertations

A multiband system including active microwave sensing and visible-near infrared reflectance spectroscopy was developed to measure unsaturated soil properties in both field and laboratory environments. Remote measurements of soil volumetric water content (θv), soil water matric potential (ψ), and soil index properties (liquid limit [LL], plastic limit [PL], and clay fraction [CF]) were conducted. Field-based measurement of θv was conducted using a ground-based radar system and field measurements within 10 percentage points of measurements acquired with traditional sampling techniques were obtained. Laboratory-based, visible and near infrared spectroscopy was found to be capable of obtaining empirical, soil specific regression functions (partial …

Trihalomethane, Dihaloacetonitrile, And Total N-Nitrosamine Precursor Adsorption By Carbon Nanotubes: The Importance Of Surface Oxides And Pore Volume, Erin Needham

Graduate Theses and Dissertations

As drinking water sources become increasingly impaired, enhanced removal of natural organic matter (NOM) may be required to curb formation of disinfection byproducts (DBPs) upon chlor(am)ination. While carbon nanotubes (CNTs) can adsorb NOM, their properties for DBP precursor adsorption have not been elucidated. Nine types of CNTs were assessed for trihalomethane (THM), dihaloacetonitrile (DHAN), and total N-nitrosamine (TONO) precursor adsorption. Batch isotherm experiments were completed with lake water and, to simulate an impaired condition, effluent from a wastewater treatment plant (WWTP). Adsorption varied with CNT type and dose, with TONO precursors having the highest percent removals from WWTP effluent (up …

Effect Of Column Axial Load On Skewed Smf Rbs Connection Demands, Clovis Desrochers

Graduate Theses and Dissertations

Steel buildings in high seismic areas often require special structural systems to transfer large lateral forces induced by earthquake accelerations. The selection of an appropriate seismic steel system (braced frame, moment frame, shear wall, etc.) is often influenced by architectural considerations. Moment frame configurations offer the most architectural flexibility, but are limited by code prequalification requirements that limit the use of non-orthogonal (skewed) beam-column connection geometries. A recent study has investigated laterally skewed moment frame connections, indicating that skew increases the potential for column twist and column flange yielding; however, it is unclear how realistic column axial loads will affect …

Numerical Simulation Of Metallic Uranium Sintering, Bruce Berry

Graduate Theses and Dissertations

Conventional ceramic oxide nuclear fuels are limited in their thermal and life-cycle properties. The desire to operate at higher burnups as is required by current utility economics has proven a formidable challenge for oxide fuel designs. Metallic formulations have superior thermal performance but are plagued by volumetric swelling due to fission gas buildup. In this study, we consider a number of specific microstructure configurations that have been experimentally shown to exhibit considerable resistance to porosity loss. Specifically, a void sizing that is bimodally distributed was shown to resist early pore loss and could provide collection sites for fission gas buildup. …

Feasibility Of Using Oxide Thickness Measurements For Predicting Crack Growth Rates In P91 Steel Components, Ralph Edward Huneycutt Iv

Graduate Theses and Dissertations

There are only few methods available for predicting the age of cracks that are found in high

temperature structural components during service; among the promising ones is the oxide

thickness measurement technique. Oxide thickness profiles are taken from crack surfaces of

components and used for predicting the rates of crack propagation. This technique is particularly

suitable for high temperature components fabricated from ferritic steels commonly used in power

plants that run on fossil fuels. To implement this technique, it is necessary to fully understand the

kinetics of high temperature oxidation in these steels. In this study, the oxidation characteristics

of …

A Comparison Of Force And Pressure Coefficients On Dome, Cube And Prism Shaped Buildings Due To Straight And Tornadic Wind Using Three Dimensional Computational Fluids Dynamics, Majdi A. A. Yousef

Graduate Theses and Dissertations

Tornadoes induce very different wind forces than a straight-line (SL) wind. A suitably designed building for a SL wind may fail when exposed to a tornado-wind of the same wind speed. It is necessary to design buildings that are more resistant to tornadoes. Most studies have been conducted to investigate tornado forces on cubic, gable-roof and cylinder buildings. However, little attention has been paid to investigate tornado force on dome buildings; hence, further research is conducted in this study. The forces on a dome, cube and prisms were analyzed and compared using Computational Fluid Dynamics (CFD) for tornadic and SL …