Engineering Commons^™

Quantitative Analysis Techniques For Assessing Organelle Organization And Dynamics In Individual Cells, Isaac Vargas

Graduate Theses and Dissertations

In biomedical optics and microscopy, the organization and morphology of organelles have been widely studied. In spite of novel imaging techniques, there is still a lack of quantitative tools to easily measure cellular characteristics from image data. Previous studies have explored multiple approaches to assess organelle organization and alignment, resulting in complicated and extensive algorithms that are both subject to multiple steps of image processing and influenced by non-cellular artifacts. In this thesis, a technique called the Modified Blanket Method (MBM) is introduced to quantify organelle organization through measurements of fractal dimension (FD) on a pixel-by-pixel basis. With the use …

Studies Of Initial Growth Of Gan On Inn, Alaa Alnami

Graduate Theses and Dissertations

III-nitride materials have recently attracted much attention for applications in both the microelectronics and optoelectronics. For optoelectronic devices, III-nitride materials with tunable energy band gaps can be used as the active region of devices to enhance the absorption or emission. A such material is indium nitride (InN), which along with gallium nitride (GaN) and aluminum nitride (AlN) embody the very real promise of forming the basis of a broad spectrum, a high efficiency solar cell. One of the remaining complications in incorporating InN into a solar cell design is the effects of the high temperature growth of the GaN crystal …

Extracting Patterns In Medical Claims Data For Predicting Opioid Overdose, Ryan Sanders

Graduate Theses and Dissertations

The goal of this project is to develop an efficient methodology for extracting features from time-dependent variables in transaction data. Transaction data is collected at varying time intervals making feature extraction more difficult. Unsupervised representational learning techniques are investigated, and the results compared with those from other feature engineering techniques. A successful methodology provides features that improve the accuracy of any machine learning technique. This methodology is then applied to insurance claims data in order to find features to predict whether a patient is at risk of overdosing on opioids. This data covers prescription, inpatient, and outpatient transactions. Features created …

Functional Importance Of Lipin Phosphorylation, Stephanie Elizabeth Hood

Graduate Theses and Dissertations

Highly conserved throughout evolution, lipins are dual functioning proteins found from yeast to humans. Functioning in the cytoplasm as phosphatidate phosphatase enzymes (PAP), lipins produce diacylglycerol that serves as a precursor for neutral fats and membrane phospholipids. Alternatively, nuclear lipins are responsible for the regulation of metabolic genes. Interestingly, both the mammalian lipin 1 paralog and the single Drosophila Lipin ortholog are highly phosphorylated proteins. Target of rapamycin (TOR) has previously been identified as one of the kinases that controls the subcellular localization of both lipin 1 and Drosophila Lipin. However, other serine and threonine kinases are predicted to be …

Fractional Order State Feedback Control For Improved Lateral Stability Of Semi-Autonomous Commercial Heavy Vehicles, Rasheed Mazen Abdulkader

Graduate Theses and Dissertations

With the growing development of autonomous and semi-autonomous large commercial heavy vehicles, the lateral stability control of articulated vehicles have caught the attention of researchers recently. Active vehicle front steering (AFS) can enhance the handling performance and stability of articulated vehicles for an emergency highway maneuver scenario. However, with large vehicles such tractor-trailers, the system becomes more complex to control and there is an increased occurrence of instabilities. This research investigates a new control scheme based on fractional calculus as a technique that ensures lateral stability of articulated large heavy vehicles during evasive highway maneuvering scenarios. The control method is …

Synthesis Of Cellulose Nanocrystal-Gold Nanoparticle Hybrid System For Surface Plasmon-Enhanced Property, Mahshid Iraniparast

Graduate Theses and Dissertations

Gold nanoparticles (AuNPs) have been brought to the forefront of various applications, ranging from theranostics, to organic photovoltaics, to biosensing owing to their localized surface plasmon resonance (LSPR) property. However, this property needs to be improved in order to allow for high sensitivity and quantitative detection of biomolecules. Hybrids of AuNPs with low-dielectric cellulose nanocrystal (CNCs) would yield enhancement of the LSPR property, which is driven by the confinement of electron oscillation at their interfaces. This study proposed a seed-mediated growth method to synthesize hybrids of CNCs-AuNPs. Sulfate groups on the surface of CNCs served as the sites for the …

Suitability Assessment For Integrated Urban Development In Makkah City Of Saudi Arabia, Mislat Alotaibi

Graduate Theses and Dissertations

Makkah – the third most populated city in Saudi Arabia with a population of 1,684,408 according to the 2010 demographic survey conducted by the Saudi General Authority for Statistics – is experiencing urban sprawl, which can be defined as an unplanned urban expansion that might degrade the environment and diminish the aesthetic view. This is a persisting problem in Makkah driven by multitude of processes involving the random expansion in its undeveloped land and the removal of its historic mountains surrounding Al-Masjid Al-Haram (the Holy Mosque) in an attempt to push the city limit of urban capacity within its administrative …

Applications Of Ionic Liquids In Membrane Separation, Mohanad Kamaz

Graduate Theses and Dissertations

Ionic liquids represent an emerging attractive material in membrane technology. The central theme of this doctoral dissertation is to develope novel membranes using ionic liquids. Two different approaches were used to prepare ionic liquid membranes including the immobilization of ionic liquid within the membrane pores or the use of pressure assembly method to deposit a selective ionic liquid layer on the top membrane surface.

In chapter 2, imidazolium ionic liquids with three different alkyl halides were successfully synthesized and used to prepare supported ionic liquid membranes (SILMs). SILMs preraper were tested for aqueous and nonaqueous applications. For nonaqueous applications, the …

Quantitative Study Of The Antimicrobial Effects Of Silver On The Motility Of Escherichia Coli, Benjamin Russell

Graduate Theses and Dissertations

In recent decades, the number of antibiotic-resistant bacterial infections has grown to become a serious global threat. This rise can be attributed to the widespread misuse of antibiotics and the lack of newly developed drugs to fight resistant organisms. Novel bactericidal substances have, therefore, garnered significant research interest. Silver, due to its powerful antimicrobial effects, is one such substance. Silver is typically most effective in cationic form; however, advancements in nanotechnology have paved the way for the controlled fabrication of nano-silver. Silver nanoparticles have been shown to have increased antibacterial potency for a variety of reasons, including the release of …

Assessing The Repeatability Of Clinical Tests In People With And Without Flexion-Induced Neck Pain, Ashton Human

Graduate Theses and Dissertations

The accessibility of mobile technology has improved productivity but can contribute to musculoskeletal disorders due to the posture associated with using such devices. Neck flexion, a posture assumed by smartphone users, has been shown as a risk factor for the development of clinical neck pain if sustained for prolonged periods. Determining the individuals who are naturally more predisposed to develop flexion-induced neck pain can aid in the prevention and treatment of musculoskeletal disorders. The purpose of this thesis is to assess the repeatability of clinical tests between trials over the course of two days in young adults who do and …

Optimizing Block-Stacking Operations With Relocation, Hueon Lee

Graduate Theses and Dissertations

The focus of the dissertation is developing the optimization problem of finding the minimum-cost operational plan of block stacking with relocation as well as devising a solution procedure to solve practical-sized instances of the problem. Assuming changeable row depth instead of permanent row depth, this research is distinguished from conventional block stacking studies.

The first contribution of the dissertation is the development of the optimization problem under the assumption of deterministic demand. The problem is modeled using integer programming as a variation of the unsplittable multi-commodity flow problem. To find a good feasible solution of practical-sized instances in reasonable time, …

Adaptive Boundary Control Using The Natural Switching Surfaces For Flyback Converters, Luciano Andres Garcia Rodriguez

Graduate Theses and Dissertations

The derivation and implementation of the natural switching surfaces (NSS) considering certain parametric uncertainties for a flyback converter operating in the boundary conduction mode (BCM) is the main focus of this paper. The NSS with nominal parameters presents many benefits for the control of nonlinear systems; for example, fast transient response under load-changing conditions. However, the performance worsens considerably when the converter actual parameters are different from the ones used in the design process. Therefore, a novel control strategy for NSS considering the effects of parameter uncertainties is proposed. This control law can estimate and adapt the control trajectories in …

Contributions Of Role-Playing Games: Advantages Of Incorporating Social Media In Disaster Response, Erin Mullin

Graduate Theses and Dissertations

After a disaster, emergency managers need to know who needs help, what type of help they need, and how soon they need it. Traditionally, they have relied on 911 calls and ground assessments to collect this information. Because the needs of a population are not able to be identified in a timely manner by ground assessments and because individuals are often unable to get through to 911, many civilians in distress turn to social media outlets as a last-ditch effort to obtain the services they need. Due to the uncertainty concerning the accuracy of social media posts, responding to disaster …

Surface Modification Of Pvdf Membranes For Treating Produced Waters By Direct Contact Membrane Distillation, Zahra Anari

Graduate Theses and Dissertations

Direct contact membrane distillation is a promising unit operation for treating hydraulic fracturing flow back and produced water. However, while a hydrophobic membrane is essential to prevent the passage of water from the feed to the permeate side, fouling by dissolved organic species can compromise membrane performance and result in wetting of the membrane pores. Here four monomers, hydroxyethylmethacrylate, acrylic acid, 1-vinyl-3-allylimidazolium bromide, and 1-vinyl-3-hexylimidazolium bromide have been grafted from the surface of a PVDF membrane. The modified and base membranes were tested in a direct contact membrane distillation system. All membranes were challenged with real produced water. In addition, …

Influence Of Single And Multiple Histidine Residues And Their Ionization Properties On Transmembrane Helix Dynamics, Orientations And Fraying, Fahmida Afrose

Graduate Theses and Dissertations

Since aromatic and charged residues are often present in various locations of transmembrane helices of integral membrane proteins, their impacts on the molecular properties of transmembrane proteins and their interactions with lipids are of particular interest in many studies. In this work, I used solid-state deuterium NMR spectroscopy in designed model peptide GWALP23 [GGALW(LA)6LWLAGA] with selective deuterium labels to addresses the pH dependence and influence of single and multiple “guest” histidine residues in the orientation and dynamic behaviors of transmembrane proteins. The mutations include Gly to His (G2/22 to H2/22), Trp to His (W5/19 to H5/19) and Leu to His …

Nematode Populations As Affected By Residue And Water Management In A Long-Term Wheat-Soybean Double Crop In Eastern Arkansas, Lucia Emperatriz Escalante Ortiz

Graduate Theses and Dissertations

Soybeans (Glycine max) are one of the major row crops in the United States, particularly in Arkansas. Soybean cyst nematode (SCN, Heterodera glycines) and southern root-knot nematode (RKN, Meloidogyne incognita) are two of the most damaging pests that cause major economic losses in soybeans. Little is known concerning the effects of common and alternative agronomic practices on nematodes in fields with nematode population densities below threshold levels. Therefore, the objective of this study was to evaluate the effects of the combination of tillage (conventional tillage and no-tillage), irrigation (irrigated and non-irrigated), wheat (Triticum aestivum) residue burning (burned and no burned), …

Development Of A Comsol Microdialysis Model, Towards Creation Of Microdialysis On A Chip With Improved Geometries And Recovery, Patrick Pysz

Graduate Theses and Dissertations

Microdialysis (µD) sampling is a diffusion-limited sampling method that has been widely used in different biomedical fields for greater than 35 years. Device calibration for in vivo studies is difficult for current non-steady state analytes of interest correlated with both inflammatory response and microbial signaling molecules (QS); which exist in low ng/mL to pg/mL with molecular weights over a wide range of 170 Da to 70 kDa. The primary performance metric, relative recovery (RR), relating the collected sample to the extracellular space concentration varies from 10% to 60% per analyte even under controlled bench-top conditions. Innovations in microdialysis device design …

Extracting Social Network From Literary Prose, Tarana Tasmin Bipasha

Graduate Theses and Dissertations

This thesis develops an approach to extract social networks from literary prose, namely, Jane Austen’s published novels from eighteenth- and nineteenth- century. Dialogue interaction plays a key role while we derive the networks, thus our technique relies upon our ability to determine when two characters are in conversation. Our process involves encoding plain literary text into the Text Encoding Initiative’s (TEI) XML format, character name identification, conversation and co-occurrence detection, and social network construction. Previous work in social network construction for literature have focused on drama, specifically manually TEI-encoded Shakespearean plays in which character interactions are much easier to track …

Evaluation And Analysis Of Null Convention Logic Circuits, John Davis Brady

Graduate Theses and Dissertations

Integrated circuit (IC) designers face many challenges in utilizing state-of-the-art technology nodes, such as the increased effects of process variation on timing analysis and heterogeneous multi-die architectures that span across multiple technologies while simultaneously increasing performance and decreasing power consumption. These challenges provide opportunity for utilization of asynchronous design paradigms due to their inherent flexibility and robustness.

While NULL Convention Logic (NCL) has been implemented in a variety of applications, current literature does not fully encompass the intricacies of NCL power performance across a variety of applications, technology nodes, circuit scale, and voltage scaling, thereby preventing further adoption and utilization …

Development Of Forward Osmosis Based Separations: A Novel Approach In Membrane Technology, Yu-Hsuan Chiao

Graduate Theses and Dissertations

Tackling the worldwide severe water shortage, the membrane technology is considered to be the most efficient approach and hence, used widely as a cost-effective sustainable solution. “Forward osmosis (FO)” has been the major attention in recent time. FO uses osmotic pressure as the driving force to draw the water passing the membrane and achieve the desired separation performance. In general, it is considered to be a process with tremendous potential to resolve the present-day water shortage with extremely low energy consumption. However, the challenges of membrane and draw solution regeneration associated with FO processes must be conquered prior to their …

Microextrusion 3d Printing Of Optical Waveguides And Microheaters, Edidiong Nseowo Udofia

Graduate Theses and Dissertations

The drive for smaller and more compact devices presents several challenges in materials and fabrication strategies. Although photolithography is a well-developed method for creating microdevices, the disparate requirements in fabrication strategies, material choices, equipment and process complexities have limited its applications. Microextrusion printing (μEP) provides a promising alternative for microfabrication. Compared to the traditional techniques, the attractions lie in the wide range of printable material choice, greater design freedom, fewer processing steps, lower cost for customized production, and the plurality of compatible substrates. However, while extrusion-based 3D printing processes have been successfully applied at the macroscale, this seeming simplicity belies …

Development Of A Multimode Instrument For Remote Measurements Of Unsaturated Soil Properties, Sean Elliott Salazar

Graduate Theses and Dissertations

The hydromechanical behavior of soil is governed by parameters that include the moisture content, soil matric potential, texture, and the mineralogical composition of the soil. Remote characterization of these and other key properties of the soil offers advantages over conventional in situ or laboratory-based measurements: information may be acquired rapidly over large, or inaccessible areas; samples do not need to be collected; and the measurements are non-destructive. A field-deployable, ground-based remote sensor, designated the Soil Observation Laser Absorption Spectrometer (SOLAS), was developed to infer parameters of bare soils and other natural surfaces over intermediate (100 m) and long (1,000 m) …

The Development Of Initial Asphalt Mixture Acceptance Criteria Using The Scb Test And The I-Fit Test, Nathan Delman Parnell

Graduate Theses and Dissertations

Cracking has become the primary asphalt pavement distress in Arkansas. Arkansas along with other states have implemented a test to measure rutting resistance. This paper presents research to implement a cracking resistance test to further modify the Superpave volumetric asphalt mixture design method in Arkansas. The Illinois Flexibility Index Test (I-FIT) was the test chosen to analyze for this research. Two aging methods were tested, a short term oven aging (AASHTO R30 ST) and a long term oven aging (NCAT) method. Six asphalt mixtures were selected to be tested. The mixtures testes were recreated from Arkansas Department of Transportation (ARDOT) …

A Simulation Tool For Evaluating The Environmental Impacts Of Management Scenarios For Modern Broiler Production Systems, Martin Andrew Christie

Graduate Theses and Dissertations

The purpose of this work is to provide a simulation tool that allows broiler production practitioners and researchers to simulate the effects of farm design and management practices on resource consumption and environmental impacts. This tool allows the user to design unique farms and simulates on farm processes required to raise broiler chicks to a marketable age. The use can input data such as farm location, broiler breed, flock size, ration type, barn dimensions, and climate control equipment specifications. The algorithms used to simulate broiler breed specific feed intake, broiler weight gain, and other on farm processes such as heating, …

Backstepping Control And Transformation Of Multi-Input Multi-Output Affine Nonlinear Systems Into A Strict Feedback Form, Khalid Salim D. Alharbi

Graduate Theses and Dissertations

This dissertation presents an improved method for controlling multi-input multi-output affine nonlinear systems. A method based on Lie derivatives of the system's outputs is proposed to transform the system into an equivalent strict feedback form. This enables using backstepping control approaches based on Lyapunov stability and integrator backstepping theory to be applied. The geometrical coordinate transformation of multi-input multi-output affine nonlinear systems into strict feedback form has not been detailed in previous publications. In this research, a new approach is presented that extends the transformation process of single-input single-output nonlinear. A general algorithm of the transformation process is formulated. The …

Toolpath Planning Methodology For Multi-Gantry Fused Filament Fabrication 3d Printing, Hieu Trung Bui

Graduate Theses and Dissertations

Additive manufacturing (AM) has revolutionized the way industries manufacture and prototype products. Fused filament fabrication (FFF) is one of the most popular processes in AM as it is inexpensive, requires low maintenance, and has high material utilization. However, the biggest drawback that prevents FFF printing from being widely implemented in large-scale production is the cycle time. The most practical approach is to allow multiple collaborating printheads to work simultaneously on different parts of the same object. However, little research has been introduced to support the aforementioned approach. Hence a new toolpath planning methodology is proposed in this paper. The objectives …

Automatic Methods To Enhance The Quality Of Colonoscopy Video, Nidhal Kareem Shukur Azawi

Graduate Theses and Dissertations

Colonoscopy is a form of endoscopy because it uses colonoscopy device to help the doctor to understand a colon patient. Enhancing the quality of Colonoscopy images is a challenge because of the wet and dynamic environment inside the colon causes many problems even the colonoscope devise has a good quality. Some of these problems are blurriness, specular highlights shiny areas.

In this work, different kinds of techniques have been investigated in order to improve the quality of colonoscopy images. Also, variety of preprocessing approaches (removing bad images, resizing images, median filtration with and without image resizing) have been conducted to …

Polarization Properties Of Airy And Ince-Gaussian Laser Beams, Sean Michael Nomoto

Graduate Theses and Dissertations

The description of polarization states of laser light as linear, circular polarization within the paraxial scalar wave approximation is adequate for most applications. However, this description falls short when considering laser light as an electromagnetic wave satisfying Maxwell's equations. An electric field with a constant unit vector for direction of the field and a space dependent complex scalar amplitude in the paraxial wave approximation does not satisfy Maxwell equations which, in general, requires all three Cartesian components of electric and magnetic fields associated for a nonzero laser beam to be nonzero.

Physical observation of passing a linearly polarized laser through …

Five-Level Flying Capacitor Converter Used As A Static Compensator For Current Unbalances In Three-Phase Distribution Systems, Rafael Franceschi

Graduate Theses and Dissertations

This thesis presents and evaluates a solution for unbalanced current loading in three-phase distribution systems. The proposed solution uses the flying capacitor multilevel converter as its main topology for an application known as Unbalanced Current Static Compensator. The fundamental theory, controller design and prototype construction will be presented along with the experimental results. The Unbalanced Current Static Compensator main objective is the balancing of the up-stream currents from the installation point to eliminate the negative- and zero-sequence currents originated by unbalanced single-phase loads.

Three separate single-phase flying capacitor converters are controlled independently using a d-q rotating reference frame algorithm to …

A Study Of Protein And Peptide-Directed Nanoparticle Synthesis For Catalytic Materials, Abdollah Mosleh

Graduate Theses and Dissertations

Nanoparticles have received much attentions due to their unique properties that makes them suitable candidates for a broad range of applications. As the size of particles decreases, their surface area-to-volume ratio would increase which is the main cause of much attention. In addition to the size, their morphologies and compositions may also play important roles for defining unique properties. Nanoparticle synthesis include both bottom-up and top-down strategies. To control the process of inorganic nanoparticles synthesis one could follow the bottom-up approach to have atom-level control over their compositions, morphologies, phases, and sizes which is the subject of this work. Due …