Engineering Commons^™

Somatic Stimulation Causes Frontoparietal Cortical Changes In Neonates: A Functional Near-Infrared Spectroscopy Study, Nasser H. Kashou, Irfaan Akram Dar, Kathryn Hasenstab, Ramzi W. Nahhas, Sudarshan R. Jadcherla

Biomedical, Industrial & Human Factors Engineering Faculty Publications

Palmar and plantar grasp are the foremost primitive neonatal reflexes and functions. Persistence of these reflexes in infancy is a sign of evolving cerebral palsy. Our aims were to establish measurement feasibility in a clinical setting and to characterize changes in oxyhemoglobin (HbO) and deoxyhemoglobin (HbD) concentration in the bilateral frontoparietal cortex in unsedated neonates at the crib-side using functional near-infrared spectroscopy (fNIRS). We hypothesized that bilateral concentration changes will occur upon somatic central and peripheral somatic stimulation. Thirteen preterm neonates (five males) underwent time 1, and six (two males) returned for time 2 (mean PMA ¼ 41.6 and 47.0 …

Nonaffine Rearrangements Of Atoms In Deformed And Quiescent Binary Glasses, Nikolai V. Priezjev

Mechanical and Materials Engineering Faculty Publications

The influence of periodic shear deformation on nonaffine atomic displacements in an amorphous solid is examined via molecular dynamics simulations. We study the three-dimensional Kob-Andersen binary mixture model at a finite temperature. It is found that when the material is periodically strained, most of the atoms undergo repetitive nonaffine displacements with amplitudes that are broadly distributed. We show that particles with large amplitudes of nonaffine displacements are organized into compact clusters. With increasing strain amplitude, spatial correlations of nonaffine displacements become increasingly long-ranged, although they remain present even in a quiescent system due to thermal fluctuations.

Flight Physician - July, 2016, Civil Aviation Medical Association

Browse all Civil Aviation Medical Association Newsletters

A twenty-one page newsletter of the Civil Aviation Medical Association. The newsletter provided news about civil aviation medicine and information related to the organization.

Carbon Nanotube Based Groundwater Remediation: The Case Of Trichloroethylene, Kshitij C. Jha, Zhuonan Liu, Hema Vijwani, Mallikarjuna Nadagouda, Sharmila M. Mukhopadhyay, Mesfin Tsige

Mechanical and Materials Engineering Faculty Publications

Adsorption of chlorinated organic contaminants (COCs) on carbon nanotubes (CNTs) has been gaining ground as a remedial platform for groundwater treatment. Applications depend on our mechanistic understanding of COC adsorption on CNTs. This paper lays out the nature of competing interactions at play in hybrid, membrane, and pure CNT based systems and presents results with the perspective of existing gaps in design strategies. First, current remediation approaches to trichloroethylene (TCE), the most ubiquitous of the COCs, is presented along with examination of forces contributing to adsorption of analogous contaminants at the molecular level. Second, we present results on TCE adsorption …

Micro-Raman Investigation Of Residual Stresses In Sic/Sic Composites, Kaitlin Kollins

The University Honors Program

Ceramic Matrix Composites (CMCs) are being developed for use in extreme operating conditions. Specifically, there is interest to replace superalloys with Silicon-Carbide/Silicon-Carbide (SiC/SiC) CMCs in the hot section of gas turbine engines because of their lower densities, high temperature performance, and oxidation resistance. Due to the high temperature processing conditions of SiC/SiC CMCs, there are thermal residual stresses inherent to the material. This study focused on using micro-Raman Spectroscopy on as manufactured SiC/SiC CMCs to measure and investigate the residual stresses within a fiber and the matrix material. Following the silicon Raman active mode at 520 cm-1 and the SiC …

Flight Physician - May, 2016, Civil Aviation Medical Association

Browse all Civil Aviation Medical Association Newsletters

A nineteen page newsletter of the Civil Aviation Medical Association. The newsletter provided news about civil aviation medicine and information related to the organization.

Finding Specific, Topic Related Information From A Sea Of Social Media Posts, Scott J. Duberstein, Daniel Asamoah, Derek Doran, Shu Z. Schiller

Celebration of Undergraduate & Graduate Research, Scholarship, and Creative Activities Materials

As social media continues to become an incredible mode of communication in daily life dealing with the exchange of information, these systems provide authors a platform where they can share their thoughts, feelings, and experiences about a number of topics. Harnessing the information expressed publicly through these modes can be incredibly powerful: public perceptions, signals, and data about a variety of specific topics could be extracted and studied from these posts. However, there is a common trade-off in collecting information about a topic from social media: the more specific the topic, generally, the more challenging it is to extract meaningful …

Wright State University's Celebration Of Research, Scholarship And Creative Activities Book Of Abstracts From Friday, April 15, 2016, Wright State University Office Of Undergraduate Research And Stemm Activities

Celebration of Undergraduate & Graduate Research, Scholarship, and Creative Activities Materials

The student abstract booklet is a compilation of abstracts from students' oral and poster presentations at Wright State University's Annual Celebration of Research, Scholarship and Creative Activities on April 15, 2016.

Comparing Network Centrality Measures Of Non-Traditional Students In An Introductory Physics Class, Emily N. Sandt, Adrienne L. Traxler

Celebration of Undergraduate & Graduate Research, Scholarship, and Creative Activities Materials

The goal of this research was to compare different models of network influence for students. Two research questions were composed: 1. How do common centrality measures compare when ranking students' network influence? 2. Do centrality values of non-traditional students show different trend than traditional students?

Nondestructive Evaluation & Radar Imaging Using Terahertz Signals, D. Amal Mirando, Michael D. Higgins, Sonya Sokhey, Matthew Larson, Douglas T. Petkie

Celebration of Undergraduate & Graduate Research, Scholarship, and Creative Activities Materials

Nondestructive imaging is a method of examining a material without direct contact that additionally does not alter the properties of the material. The terahertz imaging system currently in development uses the principle of interferometry (a Michelson Interferometer) such that frequency modulated terahertz signals are split and directed to the object under study and a reference mirror; then the detector will acquire the intensity of the combined reflected signals that contains information about the objects in the path of the beam.

Evaluation Of A Brief Marriage Intervention For Internal Behavioral Health Consultants In Military Primary Care, Ashley L. Evans, Jeffrey A. Cigrang, Tatiana D. Grey, James V. Cordova, Elizabeth Najera, Rosalyn S. Pace, Abby D. Fields, Michael A. Glotfelter, Jennifer A. Mitchell, Jolyn Tatum

Celebration of Undergraduate & Graduate Research, Scholarship, and Creative Activities Materials

Military couples face significant challenges to their relationships including demanding schedules, multiple deployments, and frequent moves. Despite the high costs of chronic marital distress, very few military (or civilian) couples seek marriage therapy. The military services and the VA system have implemented collaborative care models in primary care where internal behavioral health consultants are integrated into primary care. Integrated primary care can reduce the stigma of behavioral health services and may increase the odds that couples would seek help earlier. There are no established couple interventions designed for use in primary care. The purpose of this presentation is to describe …

Synthesis Of Functionalized Peek Analogues Via “One-Pot” Synthesis, Zachary B. Ewing, Eric A. Fossum

Celebration of Undergraduate & Graduate Research, Scholarship, and Creative Activities Materials

Poly(arylene ether)s, PAEs

• High performance engineering thermoplastic materials

• Excellent mechanical properties and thermal stability

• Resistant to hydrolysis and oxidation

• Many prepared via nucleophilic aromatic substitution (NAS)

• Electron withdrawing groups (EWG) typically in para positions

• PAEs can also be synthesized with an EWG in the meta positions, creating easily functionalized systems, with no change in the backbone

Investigating The After-Effects Of Stochastic Resonance For Use In Laparoscopic Surgery, Muhammad S. Hamdan, Caroline G. L. Cao

Celebration of Undergraduate & Graduate Research, Scholarship, and Creative Activities Materials

Laparoscopic surgery is a modern surgical technique in which surgeons insert tools through small incisions in the abdomen to perform a surgical procedure.

City360: Visualizing Multimodal City Events For Decision Support, Vaikunth Sridharan, Tanvi Banerjee, Pramod Anantharam, Archana Sheshadri, Roopteja Muppalla, Amit P. Sheth, Krishnaprasad Thirunarayan

Celebration of Undergraduate & Graduate Research, Scholarship, and Creative Activities Materials

Cities are increasingly outfitted with sensors for monitoring various conditions such as traffic, weather, air quality, and infrastructure related issues. Such well outfitted cities are generating massive amounts of multi-modal data leading to daunting challenges in assimilating, visualizing, and making sense of this data by city authorities and citizens. We propose City360 to address these challenges and provide decision support to city authorities and citizens. We demonstrate the utility of our system through concrete use cases for San Francisco Bay area that utilize heterogeneous data from various open city data sources.

Carbon-Based Hierarchical Scaffolds For Myoblast Differentiation: Synergy Between Nano-Functionalization And Alignment, Akhil Patel, Shilpaa Mukundan, Wenhu Wang, Anil K. Karumuri, Vinayak Sant, Sharmila M. Mukhopadhyay, Shilpa Sant

Mechanical and Materials Engineering Faculty Publications

While several scaffolds have been proposed for skeletal muscle regeneration, multiscale hierarchical scaffolds with the complexity of extracellular matrix (ECM) haven’t been engineered successfully. By precise control over nano- and microscale features, comprehensive understanding of the effect of multiple factors on skeletal muscle regeneration can be derived. In this study, we engineered carbon-based scaffolds with hierarchical nano- and microscale architecture with controlled physico-chemical properties. More specifically, we built multiscale hierarchy by growing carbon nanotube (CNT) carpets on two types of scaffolds, namely, interconnected microporous carbon foams and aligned carbon fiber mats. Nanostructured CNT carpets offered fine control over nano-roughness and …

Flight Physician - March, 2016, Civil Aviation Medical Association

Browse all Civil Aviation Medical Association Newsletters

A twenty-five page newsletter of the Civil Aviation Medical Association. The newsletter provided news about civil aviation medicine and information related to the organization.

Quantitative Analysis Of Retrieved Glenoid Liners, Katelyn Childs, Lynn Crosby, Tarun Goswami

Biomedical, Industrial & Human Factors Engineering Faculty Publications

Revision of orthopedic surgeries is often expensive and involves higher risk from complications. Since most total joint replacement devices use a polyethylene bearing, which serves as a weak link, the assessment of damage to the liner due to in vivo exposure is very important. The failures often are due to excessive polyethylene wear. The glenoid liners are complex and hemispherical in shape and present challenges while assessing the damage. Therefore, the study on the analysis of glenoid liners retrieved from revision surgery may lend insight into common wear patterns and improve future product designs. The purpose of this pilot study …

Long-Term Velaglucerase Alfa Treatment In Children With Gaucher Disease Type 1 Naïve To Enzyme Replacement Therapy Or Previously Treated With Imiglucerase, Laurie Smith, William Rhead, Joel Charrow, Suma P. Shankar, Ashish Bavdekar, Nicola Longo, Rebecca Mardach, Paul Harmatz, Thomas N. Hangartner, Hak-Myung Lee, Eric Crombez, Gregory M. Pastores

Biomedical, Industrial & Human Factors Engineering Faculty Publications

Background

Gaucher Disease type 1 (GD1) often manifests in childhood. Early treatment with enzyme replacement therapy (ERT) may prevent disease complications. We report the assessment of velaglucerase alfa ERT in pediatric GD1 patients who participated in a long-term extension study (HGT-GCB-044, ClinicalTrials.gov Identifier NCT00635427).

Methods

Safety and efficacy were evaluated in pediatric patients receiving velaglucerase alfa 30–60 U/kg by intravenous infusion every other week. In addition to key hematological and visceral efficacy assessments, exploratory assessments conducted specifically in pediatric patients included evaluation of height, bone age, bone marrow burden, and Tanner stage of puberty.

Results

The study included 24 …

Reversible Plastic Events During Oscillatory Deformation Of Amorphous Solids, Nikolai V. Priezjev

Mechanical and Materials Engineering Faculty Publications

The effect of oscillatory shear strain on nonaffine rearrangements of individual particles in a three-dimensional binary glass is investigated using molecular dynamics simulations. The amorphous material is represented by the Kob-Andersen mixture at the temperature well below the glass transition. We find that during periodic shear deformation of the material, some particles undergo reversible nonaffine displacements with amplitudes that are approximately power-law distributed. Our simulations show that particles with large amplitudes of nonaffine displacement exhibit a collective behavior; namely, they tend to aggregate into relatively compact clusters that become comparable with the system size near the yield strain. Along with …

Accelerated Hyperspectral Unmixing With Endmember Variability Via The Sum-Product Algorithm, Charan Puladas

Browse all Theses and Dissertations

The rich spectral information captured by hyperspectral sensors has given rise to a number of remote sensing applications, ranging from vegetative assessment and crop health monitoring, to military surveillance and combatant identification. However, due to limited spatial resolution, multiple ground materials generally contribute, i.e. mix, to form the spectrum recorded for a single pixel. The unmixing problem considers the inverse problem of determining the underlying material spectra, called endmembers, from sensor measurements. While classical unmixing approaches were deterministic in nature and did not attempt to identify in-scene materials, recent methods use labeled training data to generate statistical models of endmember …

Novel Cell Killing Mechanism Of Hydroxyurea In The Fission Yeast Schizosaccharomyces Pombe And Its Implications In Improving Antifungal Therapy, Amanpreet Singh

Browse all Theses and Dissertations

Hydroxyurea (HU, also known as hydroxycarbamide) is a well known ribonucleotide reductase (RNR) inhibitor that depletes cellular deoxyribonucleoside triphosphates (dNTPs, the building blocks of DNA). Depleted dNTP pools inside the proliferating cells stalls ongoing DNA replication forks, leading to the activation of the well-conserved DNA replication checkpoint (also known as intra-S phase checkpoint) pathway. One of the major functions of the checkpoint pathway is to protect ongoing forks from collapsing. Stalled forks, if not protected by the checkpoint pathway, lead to DNA damage and ultimately cell death. Thus it is believed that DNA damage resulting from collapsed forks is the …

The Design And Experimental Investigation Of Novel Double-Blade Wind Turbine Models Inspired By Houck's Concept, Laura E. Carpenter

Browse all Theses and Dissertations

Energy can be captured from wind turbines efficiently today. However there's always room for improvement up to the Betz's limit of 59.3% efficiency. A novel wind turbine blade was designed with double blade rotor inspired by Houck's concept in an attempt to improve the efficiency of the horizontal axis wind turbine. Scaled wind turbine models with a diameter of 150 mm were designed in SolidWorks adjusting the parameters of stagger, gap, and decalage. The general design comprises of two modern blades attached by a curved flow guide at the tip. Fourteen blade models were designed and tested to obtain power, …

An Electrolytic Capacitor-Less Approach To Eliminating Flicker In Led Lighting, Alex M. Kavouras Sr.

Browse all Theses and Dissertations

In today's lighting industry, there is a high demand for quality, long-lasting light bulbs. Light emitting diodes offer the means for long-life bulbs, while producing a quality output. The issue with the current state of solid-state lighting is how to drive LEDs and maintain their full potential. Many solutions offer either a long-life bulb or a high quality output. The trade-off for a long-lasting bulb typically comes with an output quality that is visibly or invisibly flickering. In order to effectively eliminate flicker from the output of the LED, a large output capacitor is needed. An electrolytic capacitor is a …

Feasibility Of Attaining Fully Equiaxed Microstructure Through Process Variable Control For Additive Manufacturing Of Ti-6al-4v, Sarah Louise Kuntz

Browse all Theses and Dissertations

One of the greatest challenges in additive manufacturing is fabricating titanium structures with consistent and desirable microstructure. To date, fully columnar deposits have been achieved through direct control of process variables. However, the introduction of external factors appears necessary to achieve fully equiaxed grain morphology using existing commercial processes. This work introduces and employs an analytic model to relate process variables to solidification thermal conditions and expected beta grain morphology at the surface of and at the deepest point in the melt pool. The latter is required in order to ensure the deposited microstructure is maintained even after the deposition …

Fuzzy Control Of A Hyperloop Mass Transit System, Joseph D. Plantz

Browse all Theses and Dissertations

Fuzzy logic control of a Hyperloop is carried out in this thesis. Hyperloop is being described hypothetically as a fifth mode of mass transportation and is a registered trademark of Space Exploration Technologies Corporation (SpaceX). To inspire others to help in its development and make it a reality, the Hyperloop is being explored as open-source technology by SpaceX. In this thesis a near friction-less track is constructed and is fixed inside a tunnel. External fans are used to produce air pressure inside the tunnel to propel the vehicle down the track. Fuzzy Logic Control is used to stop the vehicle …

Educational Methods For Inverted-Lecture Computer Science And Engineering Classrooms To Overcome Common Barriers To Stem Student Success, Kathleen Timmerman

Browse all Theses and Dissertations

New educational pedagogies are emerging in an effort to increase the number of new engineers available to enter the workforce in the coming years. One of the re-occurring themes in these pedagogies is variations of the flipped classroom. Often the additional classroom time gained from flipping is used to reinforce learning objectives. It is hypothesized that it might be more beneficial to students if a portion of that time is used to address common non-cognitive barriers that prevent students from succeeding in the major. In a freshman Introductory Computer Science course, three different pedagogies are compared: a hybrid lecture-active learning …

A Hybrid Approach To Aerial Video Image Registration, Karol T. Salva

Browse all Theses and Dissertations

Many video processing applications, such as motion detection and tracking, rely on accurate and robust alignment between consecutive video frames. Traditional approaches to video image registration, such as pyramidal Kanade-Lucas-Tomasi (KLT) feature detection and tracking are fast and subpixel accurate, but are not robust to large inter-frame displacements due to rotation, scale, or translation. This thesis presents an alternative hybrid approach using normalized gradient correlation (NGC) in the frequency domain and normalized cross-correlation (NCC) in the spatial domain that is fast, accurate, and robust to large displacements. A scale space search is incorporated into NGC to enable more consistent recovery …

Super-Resolution Reconstruction Of Mri, Sara Gharabaghi, Thomas Wischgoll, Nasser H. Kashou

Computer Science and Engineering Faculty Publications

Magnetic Resonance Imaging (MRI) is a non-invasive technique that is used in clinical applications such as diseases diagnosis and monitoring and treatment progress. Although, MRI scans typically have high in-plane resolution but they have very poor resolution in slice direction. Furthermore, in some applications with limited acquisition time or where the subject is moving, increased slice thickness or inter-slice space (slice gaps) may be used which results in poor resolution MRI.

In this research, we propose a novel Super Resolution (SR) technique for reconstructing High-Resolution (HR) MRI using a sequence of orthogonal Low-Resolution (LR) MRI scans.

The resolution of this …

Uncertainty-Awareness In Open Source Visualization Solutions, Christina Gillmann, Thomas Wischgoll, Hans Hagen

Computer Science and Engineering Faculty Publications

The popularity of open source tools is constantly increasing, as they offer the possibility to quickly create and use visualizations of arbitrary data sources. As the positive effects of uncertainty communication to all kinds of visualizations were discussed over the past years in the academic world, this work examines the uncertaintyawareness of open source solutions. Through a categorization and classification of available tools, this paper identifies the problems in uncertainty-awareness of available open source solutions. To solve this problem, a new paradigm of data handling that extends raw datasets by its uncertainty is suggested

Knowledge Driven Search Intent Mining, Ashutosh Jadhav

Browse all Theses and Dissertations

Understanding users' latent intents behind search queries is essential for satisfying a user's search needs. Search intent mining can help search engines to enhance its ranking of search results, enabling new search features like instant answers, personalization, search result diversification, and the recommendation of more relevant ads. Hence, there has been increasing attention on studying how to effectively mine search intents by analyzing search engine query logs. While state-of-the-art techniques can identify the domain of the queries (e.g. sports, movies, health), identifying domain-specific intent is still an open problem. Among all the topics available on the Internet, health is one …