Engineering Commons^™

Computational Investigation Of A Series Of Small Molecules As Potential Compounds For Lysyl Hydroxylase-2 (Lh2) Inhibition, Yazdan Maghsoud, Erik Antonio Vázquez-Montelongo, Xudong Yang, Chengwen Liu, Zhifeng Jing, Juhoon Lee, Matthew Harger, Ally K. Smith, Miguel Espinoza, Hou-Fu Guo, Jonathan M. Kurie, Kevin N. Dalby, Pengyu Ren, G. Andrés Cisneros

Markey Cancer Center Faculty Publications

The catalytic function of lysyl hydroxylase-2 (LH2), a member of the Fe(II)/αKG-dependent oxygenase superfamily, is to catalyze the hydroxylation of lysine to hydroxylysine in collagen, resulting in stable hydroxylysine aldehyde-derived collagen cross- links (HLCCs). Reports show that high amounts of LH2 lead to the accumulation of HLCCs, causing fibrosis and specific types of cancer metastasis. Some members of the Fe(II)/αKG-dependent family have also been reported to have intramolecular O2 tunnels, which aid in transporting one of the required cosubstrates into the active site. While LH2 can be a promising target to combat these diseases, efficacious inhibitors are still lacking. We …

Impact Of Eastern Redcedar Encroachment On Water Resources In The Nebraska Sandhills, Yaser Kishawi, Aaron R. Mittelstet, Troy E. Gilmore, Dirac Twidwell, Tirthankar Roy, Nawaraj Shrestha

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Worldwide, tree or shrub dominated woodlands have encroached into herbaceous dominated grasslands. While very few studies have evaluated the impact of Eastern Redcedar (redcedar) encroachment on the water budget, none have analyzed the impact on water quality. In this study, we evaluated the impact of redcedar encroachment on the water budget in the Nebraska Sand Hills and how the decreased streamflow would increase nitrate and atrazine concentrations in the Platte River. We calibrated a Soil and Water Assessment Tool (SWAT model) for streamflow, recharge, and evapotranspiration. Using a moving window with a dilate morphological filter, encroachment scenarios of 11.9%, 16.1%, …

Phosphorus Release And Recovery From Simulated Ferric Wastewater Sludge, Aseel Alnimer

Theses and Dissertations (Comprehensive)

Phosphorus (P) is a fundamental element necessary for all life forms and a key component in the fertilizer industry. Meanwhile, the excessive load of P to water bodies due to human activities has the potential to promote eutrophication. Wastewater treatment plants remove P either biologically or chemically and produce P rich sludge which could be a potential renewable source for P. At present, commercial technologies exist for P recovery from biological wastewater sludge. However, P recovery from chemical sludge particularly iron(III)-phosphate (Fe-P) sludge generated in chemical P removal plants that use iron(III) salts remains a challenge.

This study explored, in …

A Survey And Evaluation Of Android-Based Malware Evasion Techniques And Detection Frameworks, Parvez Faruki, Rhati Bhan, Vinesh Jain, Sajal Bhatia, Nour El Madhoun, Rajendra Pamula

School of Computer Science & Engineering Faculty Publications

Android platform security is an active area of research where malware detection techniques continuously evolve to identify novel malware and improve the timely and accurate detection of existing malware. Adversaries are constantly in charge of employing innovative techniques to avoid or prolong malware detection effectively. Past studies have shown that malware detection systems are susceptible to evasion attacks where adversaries can successfully bypass the existing security defenses and deliver the malware to the target system without being detected. The evolution of escape-resistant systems is an open research problem. This paper presents a detailed taxonomy and evaluation of Android-based malware evasion …

A Survey And Evaluation Of Android-Based Malware Evasion Techniques And Detection Frameworks, Parvez Faruki, Rhati Bhan, Vinesh Jain, Sajal Bhatia, Nour El Madhoun, Rajendra Pamula

School of Computer Science & Engineering Faculty Publications

Android platform security is an active area of research where malware detection techniques continuously evolve to identify novel malware and improve the timely and accurate detection of existing malware. Adversaries are constantly in charge of employing innovative techniques to avoid or prolong malware detection effectively. Past studies have shown that malware detection systems are susceptible to evasion attacks where adversaries can successfully bypass the existing security defenses and deliver the malware to the target system without being detected. The evolution of escape-resistant systems is an open research problem. This paper presents a detailed taxonomy and evaluation of Android-based malware evasion …

To The Moon: Strategic Competition In The Cislunar Region, Shawn M. Willis

Faculty Publications

China’s advancing space capabilities, particularly in the cislunar region, call for increased cislunar space domain awareness on the part of the United States. US military and civilian decisionmakers must take into account the full scope of China’s cislunar plans and capabilities as the military builds space strategies and future force designs. The United States must also increase near-term investments that support more robust cislunar space domain awareness.

Machine Learning Prediction Of Dod Personal Property Shipment Costs, Tiffany Tucker, Torrey J. Wagner, Paul Auclair, Brent T. Langhals

Faculty Publications

U.S. Department of Defense (DoD) personal property moves account for 15% of all domestic and international moves - accurate prediction of their cost could draw attention to outlier shipments and improve budget planning. In this work 136,140 shipments between 13 personal property shipment hubs from April 2022 through March 2023 with a total cost of $1.6B were analyzed. Shipment cost was predicted using recursive feature elimination on linear regression and XGBoost algorithms, as well as through neural network hyperparameter sweeps. Modeling was repeated after removing 28 features related to shipment hub location and branch of service to examine their influence …

Breast Density Classification Using Deep Learning, Conrad Thomas Testagrose

UNF Graduate Theses and Dissertations

Breast density screenings are an accepted means to determine a patient's predisposed risk of breast cancer development. Although the direct correlation is not fully understood, breast cancer risk increases with higher levels of mammographic breast density. Radiologists visually assess a patient's breast density using mammogram images and assign a density score based on four breast density categories outlined by the Breast Imaging and Reporting Data Systems (BI-RADS). There have been efforts to develop automated tools that assist radiologists with increasing workloads and to help reduce the intra- and inter-rater variability between radiologists. In this thesis, I explored two deep-learning-based approaches …

Ovulation Prediction Using Random Forest Algorithm On Physiological Data, Kimberly D. Laynes

UNF Graduate Theses and Dissertations

Human infertility rates are on the rise -- studies have shown that one in every four women have trouble conceiving and every year those rates are rising [Halleran22]. This trend motivates procedures such as in-vitro fertilization (IVF) and intrauterine insemination (IUI) to produce a pregnancy. Such procedures are not only intricate and expensive but also carry potential unintended consequences for women's physical and mental well-being. A more profound comprehension of the menstrual cycle and its multiple phases, particularly detecting the ovulation period itself, promotes optimized treatment outcomes and reduces associated risks. To facilitate ovulation detection, new sensing technologies built into …

Development Of High Kinetic Inductance Superconducting Nanowire Devices On High Permittivity Strontium Titanate Substrates, Jamie Timmons

UNF Graduate Theses and Dissertations

This thesis involves the fabrication and characterization of devices made from two different superconducting materials: yttrium barium copper oxide (YBCO), a high-TC complex oxide, and niobium nitride (NbN), a low-TC transition metal nitride. Both types of devices are fabricated on strontium titanate substrates, which provides a good lattice match to YBCO and also an extremely large permittivity at low temperature. We demonstrate that wet etching of YBCO thin films via bromine can be a viable microfrabriation technique for the material. Using approximately 35 nm thick epitaxially grown YBCO on an STO substrate, we were able to fabricate YBCO “microwires” with …

Alternatives To Reducing Aviation Fuel-Burn With Technology: Fully Electric Autonomous Taxibot, Denzil Neo

Student Works

Aircraft taxiing operations in the aerodrome were identified to consume the most jet fuel apart from the cruise phase of the flight. This was also well supported by various research associating taxi operations at large, congested airports, with high jet fuel consumption, high carbon emissions, and noise pollution. Existing literature recognised the potential to address the environmental issues of aerodrome taxi operations by operating External or Onboard Aircraft Ground Propulsion Systems (AGPS). Designed to power aircraft with sources other than their main engines, external Aircraft Ground Power Systems (AGPS) have shown the potential to significantly cut jet fuel consumption and …

Directional Speaker Poster, Eugene Ng, Bryan Wong, Ruhaan Das

Student Works

Changi Airport is set to expand with a new terminal, Terminal 5. Currently, many of the airport's processes are manual, requiring a high dependence on staff. This proposal aims to incorporate automation and AI for a smoother passenger experience.

Application Of Big Data Technology, Text Classification, And Azure Machine Learning For Financial Risk Management Using Data Science Methodology, Oluwaseyi A. Ijogun

College of Graduate Studies: Theses & Dissertations

Data science plays a crucial role in enabling organizations to optimize data-driven opportunities within financial risk management. It involves identifying, assessing, and mitigating risks, ultimately safeguarding investments, reducing uncertainty, ensuring regulatory compliance, enhancing decision-making, and fostering long-term sustainability. This thesis explores three facets of Data Science projects: enhancing customer understanding, fraud prevention, and predictive analysis, with the goal of improving existing tools and enabling more informed decision-making. The first project examined leveraged big data technologies, such as Hadoop and Spark, to enhance financial risk management by accurately predicting loan defaulters and their repayment likelihood. In the second project, we investigated …

Comparative Analysis Of Fullstack Development Technologies: Frontend, Backend And Database, Qozeem Odeniran

College of Graduate Studies: Theses & Dissertations

Accessing websites with various devices has brought changes in the field of application development. The choice of cross-platform, reusable frameworks is very crucial in this era. This thesis embarks in the evaluation of front-end, back-end, and database technologies to address the status quo. Study-a explores front-end development, focusing on angular.js and react.js. Using these frameworks, comparative web applications were created and evaluated locally. Important insights were obtained through benchmark tests, lighthouse metrics, and architectural evaluations. React.js proves to be a performance leader in spite of the possible influence of a virtual machine, opening the door for additional research. Study b …

Material Extrusion-Based Additive Manufacturing: G-Code And Firmware Attacks And Defense Frameworks, Haris Rais

Theses and Dissertations

Additive Manufacturing (AM) refers to a group of manufacturing processes that create physical objects by sequentially depositing thin layers. AM enables highly customized production with minimal material wastage, rapid and inexpensive prototyping, and the production of complex assemblies as single parts in smaller production facilities. These features make AM an essential component of Industry 4.0 or Smart Manufacturing. It is now used to print functional components for aircraft, rocket engines, automobiles, medical implants, and more. However, the increased popularity of AM also raises concerns about cybersecurity. Researchers have demonstrated strength degradation attacks on printed objects by injecting cavities in the …

Comparative Study On Development Of Novel Catalytic Oxidation For Removing Emerging Contaminants, Abdul H. Asif

Theses: Doctorates and Masters

‘Wastewater treatment’ is not itself a new concept, where global water bodies have been polluted since the evolution of mankind. As a result of human activities including domestic, industrial and commercial practices, levels of water pollution through aqueous contaminants are increasing every day. Moreover, rapid industrialisation and recent human progress has given rise to a new classification of pollution, that of emerging contaminants (ECs). Further, these chemicals are highly resistant to biodegradation and are capable of travelling, where they can penetrate from one part of the world to another. Whilst traditional wastewater treatment techniques, such as adsorption, might be effective …

Enhancing The Performance Of Federated Learning With Diffusion Models: Leveraging Synthetic Data To Address Non-Iid Data Challenges, Karin Huangsuwan

Chulalongkorn University Theses and Dissertations (Chula ETD)

In the context of machine learning in healthcare, federated learning (FL) is frequently seen as an effective approach to tackling issues of data privacy and distribution. Nonetheless, many real-world datasets exhibit non-identical and independently distributed (non-IID) characteristics, meaning that data features vary across different institutions. This non-IID nature presents challenges for FL model convergence, such as client drifting, where model weights lean towards local optima rather than global optimum. To address these issues, we introduce a new framework called "FedDrip (Federated Learning with Diffusion Reinforcement at Pseudo-site)," which leverages diffusion-generated synthetic data to mitigate data-related problems in non-IID settings. Our …

Predicting Newcomer’S Turnover Using Predictive Analytics : A Case Study Of Thai Financial Firm In Bangkok, Thailand, Meena Kittikunsiri

Chulalongkorn University Theses and Dissertations (Chula ETD)

Employee turnover, a critical issue impacting workplace productivity, has prompted organizations to leverage machine learning techniques for predictive analysis. This study specifically targets the prediction of turnover among new employees, utilizing data obtained from a survey conducted at a Thai financial firm in Bangkok, Thailand. Through an evaluation of various machine learning models, the results indicate that the Random Forest model surpasses others. Furthermore, this research highlights crucial factors influencing newcomer turnover, such as comfort with workplace culture, work-from-home policies, onboarding programs, and satisfaction with the recruitment process. These findings offer actionable insights for HR professionals to focus on these …

Cybersecurity And Digital Privacy Aspects Of V2x In The Ev Charging Structure, Umit Cali, Murat Kuzlu, Onur Elma, Osman Gazi Gucluturk, Ahmet Kilic, Ferhat Ozgur Catak

Engineering Technology Faculty Publications

With the advancement of green energy technology and rising public and political acceptance, electric vehicles (EVs) have grown in popularity. Electric motors, batteries, and charging systems are considered major components of EVs. The electric power infrastructure has been designed to accommodate the needs of EVs, with an emphasis on bidirectional power flow to facilitate power exchange. Furthermore, the communication infrastructure has been enhanced to enable cars to communicate and exchange information with one another, also known as Vehicle-to-Everything (V2X) technology. V2X is positioned to become a bigger and smarter system in the future of transportation, thanks to upcoming digital technologies …

Teaching Data Acquisition Through The Arduino-Driven Home Weather Station Project, Sheryl Dutton, Kurt Galderisi, Murat Kuzlu, Otilia Popescu, Vukica Jovanovic

Engineering Technology Faculty Publications

The main objective of this paper is to present one possible way to engage undergraduate students in designing a system that uses the Internet of Things (IoT) strategy for data acquisition and management. The MATLAB home weather station project presented here was developed by a team of students for the senior design course in the Electrical Engineering Technology undergraduate program at Old Dominion University (ODU). The main purpose of this project was for undergraduate students to learn how to create a localized, compact, and precise weather station. Utilizing various sensors, both homemade and sourced online, this weather station is capable …

Development Of A Simevents Model For Printed Circuit Board (Pcb) Assembly Processes, Siqin Dong, Mileta Tomovic, Krishnanand Kaipa

Engineering Technology Faculty Publications

Printed circuit boards (PCBs) are the foundational building blocks of most modern electronic devices. PCB assembly is defined as the process of mounting different electronic components on a PCB. Circuit board assembly utilizes an automated technique with most steps completed by machines for different operations (e.g., pick-and-place components, soldering, etc.). In this paper, details of a student course project, carried out at Old Dominion University, on the design and simulation of PCB assembly processes based on MATLAB discrete-event system are presented. An essential component in the advanced manufacturing technology course is the hands-on experience where students implement multiple software simulation …

Molecular Elucidation Of Reaction Mechanisms In Aluminum & Lithium Metal Batteries By Solid-State Nmr Spectroscopy And Electrochemical Methods, Leo W. Gordon

Dissertations and Theses

As society wrestles with the ever-growing climate consequences of burning fossil fuels, the increased demand for electric vehicles and renewable power generation mandates safe, sustainable, earth-abundant, low cost, and energy dense batteries. Different use cases will necessitate different types of batteries; for example, stationary storage systems prioritize minimal expense, whereas mobile applications like electric vehicles emphasize high energy densities. Aluminum and lithium metal batteries hold great promise for next-generation energy storage due to their large specific capacities (2980 mA h g^-1, and 3860 mA h g^-1, respectively). In particular, aluminum metal is low cost, has high …

Exploring Information Leakage In Historical Stock Market Data, Edison Hua

Dissertations and Theses

Information leakage is a major concern for traders who want to execute large orders without affecting the market price. In this paper, we explore the sources and effects of information leakage in historical stock market data using various methods and metrics. We first define information leakage as a pattern caused by a trader that would otherwise not occur without the trader’s activity. Using historical data, the direct impact of a potential large trade cannot be measured, but we consider a minimal impact large trade to be one that minimizes changes to the established trading data. We then analyze how information …

Anomaly Based Intrusion Detection System Through Remote Virtual Machine Introspection, Huseyn Huseynov

Dissertations and Theses

Research on identifying malicious applications is an important direction in information security, especially when it comes to detection of evasive malware such as keyloggers, trojans, rootkits and their derivatives. Inspired by a biological immune system and based on negative selection algorithm approach to detect various types of malwares is proposed in this paper.

By deeply studying Linux kernel, understanding links behind different internal system processes, examining, and experimenting with hundreds of various keyloggers we propose a single Artificial Intelligence based solution as a comprehensive protection against wide range of malwares. Developed Intrusion Detection System (IDS) can be deployed in the …

Optimization Of Optical Nanosensor Response For The Detection Of Anthracyclines Using A Binary Machine Learning Classifier, Myesha Thahsin

Dissertations and Theses

Pharmacokinetic variables such as interindividual variation in metabolizing and eliminating drugs makes dose selection of chemotherapeutic anthracyclines difficult. One potential solution to determining dosing levels of an anthracycline is the development of non-invasive sensors to monitor their pharmacology in vivo. Single-walled carbon nanotubes (SWCNT) have substantial potential for in vivo sensor development, as they exhibit near-infrared fluorescence in the tissue-transparent window and a robust response to their local environment. An emerging method for evaluating and optimizing SWCNT sensor response is through machine learning. In this study, anthracyclines Daunorubicin, Doxorubicin, Epirubicin, Mitoxantrone and Idarubicin, were used to interrogate 12 SWCNT preparations …

Synthesis And Application Of Redox-Active Covalent Organic Frameworks In Rechargeable Batteries, Mohammad K. Shehab

Theses and Dissertations

Synthesis and Application of Redox-Active Covalent Organic Frameworks in Rechargeable Batteries

Mohammad K. Shehab

Department of Chemistry, Virginia Commonwealth University, Richmond, Virginia 23284, United States

Abstract

In recent years, lithium-ion batteries (LIBs) have been considered the dominant energy storage devices for portable electronics and electric vehicles due to their high energy density, low self-discharge rate, and long cycle life. In LIBs, the traditional positive electrodes employed are mainly derived from metal-containing inorganic compounds composed of cobalt, iron, nickel, or manganese (LiCoO₂, LiMn₂O₄, and LiFePO₄) coupled with graphite as the negative electrode. Despite …

Mechanisms Of Emulsion Destabilization: An Investigation Of Surfactant, Stabilizer, And Detergent Based Formulations Using Diffusing Wave Spectroscopy, Jordan N. Nowaczyk

Theses and Dissertations

Conventional approaches for studying emulsions, such as microscopy and macroscopic phase tracking, present challenges when it comes to establishing detailed mechanistic descriptions of the impact of emulsifier and stabilizer additives. Additionally, while a combination of sizing methods and macroscopic phase tracking can provide insights into droplet size changes and concentration, the use of multiple measurements can be cumbersome and error-prone. It is the focus of this work, to present a new method for studying water in oil (W/O) emulsions that involves using diffusing wave spectroscopy (DWS) to examine the impact of three different surface stabilizing additives at varying concentrations. By …

A Novel Technique For The Quantitative Determination Of Wettability Of A Severely Heterogeneous Tight Carbonate Reservoir, Saleh Al-Sayegh, Ralph E. Flori, Waleed Al-Bazzaz, Abdulaziz Abbas, Ali Qubian, Hasan Al-Saedi

Geosciences and Geological and Petroleum Engineering Faculty Research & Creative Works

The objective of this study is to accurately measure the wettability contact angle of a cretaceous carbonate reservoir in a vertical well set-up known for as an unconventional tight carbonate oil reservoir. Also, to investigate the relative heterogeneity of these samples using digitally captured images; these images accurately capture natural pore-system in this carbonate rock samples and their wettability performance attributed towards building a vertical depth wettability/heterogeneity model. To capture, measure and model natural tight matrix static contact angle wettability in order to understand their new physics that will advance unconventional tight oil reservoir characterization. Entire vertical well depth reservoir …

Practical Imaging Applications Of Wettability Contact Angles On Kuwaiti Tight Carbonate Reservoir With Different Rock Types, Saleh Al-Sayegh, Ralph E. Flori, Waleed Al-Bazzaz, Sohaib Kholosy, Hasan Al-Saedi, Abdulaziz Abbas, Ali Qubian

Geosciences and Geological and Petroleum Engineering Faculty Research & Creative Works

This study focuses on a tight carbonate reservoir which is located in Northern Kuwait and is classified as an unconventional reservoir. A practical imaging technique of wettability contact angle (θ°) presents "big data" as well as relative-permeability (Krw and Kro) measurements. Also, modeling, through rock image technology, the vast well-documented grain/pore boundary morphology available inside fresh rock fragments have achieved good results. Conventional laboratory relative-permeability experiments are expensive and time-consuming. This study introduces a novel method to measure/calculate relative permeability through fast, less expensive, non-destructive, and environmentally friendly techniques of imaging technology. One tight carbonate reservoir is selected, imaged, processed, …

Transport And Plugging Performance Evaluation Of A Novel Re-Crosslinkable Microgel Used For Conformance Control In Mature Oilfields With Super-Permeable Channels, Adel Alotibi, T. Song, Baojun Bai, Thomas P. Schuman

Geosciences and Geological and Petroleum Engineering Faculty Research & Creative Works

Preformed particle gels (PPG) have been widely applied in oilfields to control excessive water production. However, PPG has limited success in treating opening features because the particles can be flushed readily during post-water flooding. We have developed a novel micro-sized Re-crosslinkable PPG (micro-RPPG) to solve the problem. The microgel can re-crosslink to form a bulk gel, avoiding being washed out easily. This paper evaluates the novel microgels' transport and plugging performance through super-permeable channels. Micro-RPPG was synthesized and evaluated for this study. Its storage moduli after fully swelling are approximately 82 Pa. The microgel characterization, self-healing process, transportation behavior, and …