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Articles 10201 - 10230 of 13830

Full-Text Articles in Engineering

Safety And Protective Efficacy Of Ina-Inactivated Venezuelan Equine Encephalitis Virus: Implication In Vaccine Development, Anuj Sharma, Paridhi Gupta, Pamela J. Glass, Michael D. Parker, Radha K. Maheshwari Jan 2011

Safety And Protective Efficacy Of Ina-Inactivated Venezuelan Equine Encephalitis Virus: Implication In Vaccine Development, Anuj Sharma, Paridhi Gupta, Pamela J. Glass, Michael D. Parker, Radha K. Maheshwari

United States Army: Publications

We have previously shown that a hydrophobic alkylating compound, 1,5-iodonaphthyl-azide (INA) can efficiently inactivate the virulent strain of Venezuelan equine encephalitis virus (VEEV), V3000 in vitro. In this study, we have evaluated the safety of INA-inactivated V3000 and V3526 and the protective efficacy of INA-inactivated V3000. INA-inactivated V3000 and V3526 did not cause disease in suckling mice. RNA isolated from the INA-inactivated V3000 and V3526 was also not infectious. Immunization of adult mice with INA-inactivated V3000 induced an anti-VEEV antibody response and protected mice from virulent VEEV challenge. The protective efficacy of INA-inactivated V3000 increased with the use of adjuvants. …

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Dislocation–Twin Interactions In Nanocrystalline Fcc Metals, Y. T. Zhu, X. L. Wu, X. Z. Liao, J. Narayan, L. J. Keckés, S. N. Mathaudhu Jan 2011

Dislocation–Twin Interactions In Nanocrystalline Fcc Metals, Y. T. Zhu, X. L. Wu, X. Z. Liao, J. Narayan, L. J. Keckés, S. N. Mathaudhu

United States Army: Publications

Dislocation interaction with and accumulation at twin boundaries have been reported to significantly improve the strength and ductility of nanostructured face-centered cubic (fcc) metals and alloys. Here we systematically describe plausible dislocation interactions at twin boundaries. Depending on the characteristics of the dislocations and the driving stress, possible dislocation reactions at twin boundaries include cross-slip into the twinning plane to cause twin growth or de-twinning, formation of a sessile stair-rod dislocation at the twin boundary, and transmission across the twin boundary. The energy barriers for these dislocation reactions are described and compared.

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The Impact Of 3pl’S Green Initiatives On The Purchasing Of Transport And Logistics Services: An Exploratory Study, Pietro Evangelista, Maria Huge-Brodin, Karin Isaksson, Edward Sweeney Jan 2011

The Impact Of 3pl’S Green Initiatives On The Purchasing Of Transport And Logistics Services: An Exploratory Study, Pietro Evangelista, Maria Huge-Brodin, Karin Isaksson, Edward Sweeney

Conference papers

There is a lack of research investigating the interaction and reciprocal influences between the buyer perspective and the supplier of transport and logistics services. Studies on the buyer perspective analyse the selection criteria to buy 3PL services, while research focused on green 3PL services examine initiatives undertaken by these companies to provide more environmentally sustainable services. The objective of this paper is to fill this void through an explorative case study analysis on the environmental attitude of 3PL companies in order to derive relevant implications for buyer’s behaviour. The results provide useful guidelines to buyers for understanding awareness, initiatives as …

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An Alternative Approach To Integrating Plasticity Relations, Richard Becker Jan 2011

An Alternative Approach To Integrating Plasticity Relations, Richard Becker

United States Army: Publications

A new plasticity integration algorithm is proposed based upon observations from the closed form integration of a generalized quadratic yield function over a single time step. The key to the approach is specification of the normal to the plastic flow potential as a function of the current state and strain increment. This uniquely defines the direction of the stress tensor for a convex, non-faceted flow potential. The stress magnitude and plastic strain increment are computed to satisfy the yield function. A non-quadratic, isotropic, associative flow model is coded to demonstrate accuracy and time step convergence following a step change in …

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Nanoindentation Characterization Of Deformation And Failure Of Aluminum Oxynitride, J. J. Guo, K. Wang, T. Fujita, J. W. Mccauley, J. P. Singh, M. W. Chen Jan 2011

Nanoindentation Characterization Of Deformation And Failure Of Aluminum Oxynitride, J. J. Guo, K. Wang, T. Fujita, J. W. Mccauley, J. P. Singh, M. W. Chen

United States Army: Publications

A systematic study of the mechanical deformation and failure of transparent ceramic aluminum oxynitride (AlON) has been conducted using a depth-sensitive nanoindentation technique combined with transmission electron microscopy (TEM) and Raman spectroscopy. Although discrete displacement bursts appear in the load–depth profiles at high applied forces, a detectable high-pressure phase transition has not been found by means of micro-Raman spectroscopy and TEM. Instead, a high density of dissociated (1 1 0) dislocations can be observed underneath the nanoindenters, suggesting that extensive plastic deformation takes place in the brittle ceramic at high contact pressures. Moreover, nanoindentation-induced micro-cracks oriented along well-defined crystallographic planes …

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Development Of A Cognitive Work Analysis Framework Tutorial Using Systems Modeling Language, Wilfred Henry Wells Jan 2011

Development Of A Cognitive Work Analysis Framework Tutorial Using Systems Modeling Language, Wilfred Henry Wells

Electronic Theses and Dissertations

At the present time, most systems engineers do not have access to cognitive work analysis information or training in terms they can understand. This may lead to a disregard of the cognitive aspect of system design. The impact of this issue is system requirements that do not account for the cognitive strengths and limitations of users. Systems engineers cannot design effective decision support systems without defining cognitive work requirements. In order to improve system requirements, integration of cognitive work requirements into the systems engineering process has to be improved. One option to address this gap is the development of a …

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Introduction: Advances In E-Business Engineering, Ling Li Jan 2011

Introduction: Advances In E-Business Engineering, Ling Li

Information Technology & Decision Sciences Faculty Publications

(First paragraph) E-business is more than just e-commerce. It is one of the most challenging areas for industry and research communities. E-business has evolved from business-to-business, business-to-customer, customer-to-business, customer-to-customer, and business-to-government systems to the integrated and collaborative business services among various information systems and e-marketplaces. In this evolving process, integrated e-business systems and their related supporting platforms have to be rapidly designed and developed in order to meet different requirements. A variety of e-business engineering paradigms and technologies have been developed to tackle these challenges. There are many research issues needed to be addressed. These issues include heterogeneous services integration, …

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Protective Immunity To Pre-Erythrocytic Stage Malaria, Robert J. Schwenk, Thomas L. Richie Jan 2011

Protective Immunity To Pre-Erythrocytic Stage Malaria, Robert J. Schwenk, Thomas L. Richie

United States Army: Publications

The development of a vaccine against malaria is a major research priority given the burden of disease, death and economic loss inflicted upon the tropical world by this parasite. Despite decades of effort, however, a vaccine remains elusive. The best candidate is a subunit vaccine termed RTS,S but this provides only partial protection against clinical disease. This review examines what is known about protective immunity against pre-erythrocytic stage malaria by considering the humoral and T cell-mediated immune responses that are induced by attenuated sporozoites and by the RTS,S vaccine. On the basis of these observations a set of research priorities …

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A New Explanation Of The Extinction Paradox, Matthew J. Berg, C. M. Sorensen, A. Chakrabarti Jan 2011

A New Explanation Of The Extinction Paradox, Matthew J. Berg, C. M. Sorensen, A. Chakrabarti

United States Army: Publications

This work presents a new explanation for the extinction paradox and shows that the canonical explanations are incorrect. This paradox refers to the large size limit of a particle’s extinction cross section. It is called a paradox because the geometrical optics approximation, which should be valid in this limit, predicts a cross section that is half of the true value. The new explanation is achieved by formulating the scattered wave in terms of an integral over the particle’s surface where the seemingly unrelated Ewald–Oseen theorem appears in the formulation. By expressing the cross section in terms of this surface integral, …

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Clostridium Difficile Infections In Patients With Severe Burns, Scott J. Crabtree, Janelle L. Robertson, Kevin K. Chung, Evan M. Renz, Steven E. Wolf, Duane R. Hospenthal, Clinton K. Murray Jan 2011

Clostridium Difficile Infections In Patients With Severe Burns, Scott J. Crabtree, Janelle L. Robertson, Kevin K. Chung, Evan M. Renz, Steven E. Wolf, Duane R. Hospenthal, Clinton K. Murray

United States Army: Publications

With improved survival in burn patients, Clostridium difficile infection (CDI) remains a significant potential complication. The incidence of, risk factors for, and outcomes of CDI in severely burned patients are poorly studied and remain unclear. This study involves retrospective case control and cohort studies using electronic medical records from February 1, 2002 to January 31, 2009 at the US Department of Defense’s only burn unit. Demographic, risk factor, and outcome data were collected for all C. difficile toxin positive patients in the burn, medical, and surgical intensive care units and the hospital’s step down unit along with an additional analysis …

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Determination Of Threshold Adverse Effect Doses Of Percutaneous Vx Exposure In African Green Monkeys, Raymond F. Genovese, Bernard J. Benton, John L. Oubre, Christopher E. Byers, E. Michael Jakubowski, Robert J. Mioduszewski, Timothy J. Settle, Thomas J. Steinbach Jan 2011

Determination Of Threshold Adverse Effect Doses Of Percutaneous Vx Exposure In African Green Monkeys, Raymond F. Genovese, Bernard J. Benton, John L. Oubre, Christopher E. Byers, E. Michael Jakubowski, Robert J. Mioduszewski, Timothy J. Settle, Thomas J. Steinbach

United States Army: Publications

Percutaneous exposure to the chemical warfare nerve agent VX was evaluated in African green monkeys (n = 9). Doses of VX (7.5–100 μg/kg) were applied to the skin for 60 min and residual agent was quantified (before decontamination) to estimate the absorbed dose. Monkeys were evaluated for the presence or absence of clinical signs of toxicity and blood was sampled periodically (30 min–12 weeks) following exposure to measure the degree of circulating acetylcholinesterase (AChE) inhibition. Monkeys were also evaluated for behavioral changes fromVXexposure using a serial probe recognition (SPR) task. The lowest observable adverse effect level (LOAEL) for the production …

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Mechanical Response Of Pig Skin Under Dynamic Tensile Loading, Jaeyoung Lim, Jihye Hong, Weinong W. Chen, Tusit Weerasooriya Jan 2011

Mechanical Response Of Pig Skin Under Dynamic Tensile Loading, Jaeyoung Lim, Jihye Hong, Weinong W. Chen, Tusit Weerasooriya

United States Army: Publications

Uniaxial tensile experiments were performed on pig skin to investigate the tensile stressestrain response at both quasi-static and dynamic rates of deformation. A Kolsky tension bar, also called a split Hopkinson tension bar (SHTB), was modified to conduct the dynamic experiments. Semiconductor strain gages were used to measure the low levels of the transmitted signal from pig skin. A pulse shaper technique was used for generating a suitable incident pulse to ensure stress equilibrium and approximate constant strain rate in the specimen of a thin skin sheet wrapped around the ends of the bars for minimizing radial inertia. In order …

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Detection Of Six Serotypes Of Botulinum Neurotoxin Using Fluorogenic Reporters, Daniel R. Ruge, F. Mark Dunning, Timothy M. Piazza, Brian E. Molles, Michael Adler, Füsûn N. Zeytin, Ward C. Tucker Jan 2011

Detection Of Six Serotypes Of Botulinum Neurotoxin Using Fluorogenic Reporters, Daniel R. Ruge, F. Mark Dunning, Timothy M. Piazza, Brian E. Molles, Michael Adler, Füsûn N. Zeytin, Ward C. Tucker

United States Army: Publications

Methods that do not require animal sacrifice to detect botulinum neurotoxins (BoNTs) are critical for BoNT antagonist discovery and the advancement of quantitative assays for biodefense and pharmaceutical applications. Here we describe the development and optimization of fluorogenic reporters that detect the proteolytic activity of BoNT/A, B, D, E, F, and G serotypes in real time with femtomolar to picomolar sensitivity. Notably, the reporters can detect femtomolar concentrations of BoNT/A in 4 h and BoNT/E in 20 h, sensitivity that equals that of animal-based methods. The reporters can be used to determine the specific activity of BoNT preparations with intra- …

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Prophylaxis With Human Serum Butyrylcholinesterase Protects Guinea Pigs Exposed To Multiple Lethal Doses Of Soman Or Vx, Ashima Saxena, Wei Sun, James M. Fedorko, Irwin Koplovitz, Bhupendra P. Doctor Jan 2011

Prophylaxis With Human Serum Butyrylcholinesterase Protects Guinea Pigs Exposed To Multiple Lethal Doses Of Soman Or Vx, Ashima Saxena, Wei Sun, James M. Fedorko, Irwin Koplovitz, Bhupendra P. Doctor

United States Army: Publications

Human serum butyrylcholinesterase (Hu BChE) is currently under advanced development as a bioscavenger for the prophylaxis of organophosphorus (OP) nerve agent toxicity in humans. It is estimated that a dose of 200 mg will be required to protect a human against 2 × LD50 of soman. To provide data for initiating an investigational new drug application for the use of this enzyme as a bioscavenger in humans, we purified enzyme from Cohn fraction IV-4 paste and initiated safety and efficacy evaluations in mice, guinea pigs, and non-human primates. In mice, we demonstrated that a single dose of enzyme that …

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Microstructure And Mechanical Properties At Different Length Scales And Strain Rates Of Nanocrystalline Tantalum Produced By High-Pressure Torsion, Q. Wei, Z. L. Pan, X. L. Wu, B. E. Schuster, L. J. Kecdkes, R. Z. Valiev Jan 2011

Microstructure And Mechanical Properties At Different Length Scales And Strain Rates Of Nanocrystalline Tantalum Produced By High-Pressure Torsion, Q. Wei, Z. L. Pan, X. L. Wu, B. E. Schuster, L. J. Kecdkes, R. Z. Valiev

United States Army: Publications

Fully dense, nanocrystalline tantalum (average grain size as small as ~40 nm) has been processed for the first time by high-pressure torsion. High-resolution transmission electron microscopy reveals non-equilibrium grain boundaries and grains decorated with high-density dislocations. Microhardness measurements and instrumented nanoindentation experiments indicate that the mechanical property is quite uniform except for the central area of the disks. Nanoindentation experiments at different strain rates suggest that the strain rate sensitivity of nanocrystalline tantalum is increased compared to the coarse- and ultrafine-grained counterparts and is accompanied by an activation energy of the order of a few ~b3 (b is the magnitude …

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Self Learning Strategies For Experimental Design And Response Surface Optimization, Adel Alaeddini Jan 2011

Self Learning Strategies For Experimental Design And Response Surface Optimization, Adel Alaeddini

Wayne State University Dissertations

Most preset RSM designs offer ease of implementation and good performance over a wide range of process and design optimization applications. These designs often lack the ability to adapt the design based on the characteristics of application and experimental space so as to reduce the number of experiments necessary. Hence, they are not cost effective for applications where the cost of experimentation is high or when the experimentation resources are limited. In this dissertation, we present a number of self-learning strategies for optimization of different types of response surfaces for industrial experiments with noise, high experimentation cost, and requiring high …

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Novel Models And Algorithms For Systems Reliability Modeling And Optimization, Dingzhou Cao Jan 2011

Novel Models And Algorithms For Systems Reliability Modeling And Optimization, Dingzhou Cao

Wayne State University Dissertations

Recent growth in the scale and complexity of products and technologies in the defense and other industries is challenging product development, realization, and sustainment costs. Uncontrolled costs and routine budget overruns are causing all parties involved to seek lean product development processes and treatment of reliability, availability, and maintainability of the system as a true "design parameter". To this effect, accurate estimation and management of the system reliability of a design during the "earliest stages" of new product development is not only critical for managing product development and manufacturing costs but also to control life cycle costs (LCC). In this …

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Hazard Rate Models For Early Warranty Issue Detection Using Upstream Supply Chain Information, Chongwen Zhou Jan 2011

Hazard Rate Models For Early Warranty Issue Detection Using Upstream Supply Chain Information, Chongwen Zhou

Wayne State University Dissertations

This research presents a statistical methodology to construct an early automotive warranty issue detection model based on upstream supply chain information. This is contrary to extant methods that are mostly reactive and only rely on data available from the OEMs (original equipment manufacturers). For any upstream supply chain information with direct history from warranty claims, the research proposes hazard rate models to link upstream supply chain information as explanatory covariates for early detection of warranty issues. For any upstream supply chain information without direct warranty claims history, we introduce Bayesian hazard rate models to account for uncertainties of the explanatory …

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Digital Holographic Imaging Of Aerosol Particles In Flight, Matthew J. Berg, Gorden Videen Jan 2011

Digital Holographic Imaging Of Aerosol Particles In Flight, Matthew J. Berg, Gorden Videen

United States Army: Publications

This work describes the design and application of an apparatus to image aerosol
particles using digital holography in a flow-through, contact-free manner. Particles in an aerosol stream are illuminated by a triggered, pulsed laser and the pattern produced by the interference of this light with that scattered by the particles is recorded by a digital camera. The recorded pattern constitutes a digital hologram from which an image of the particles is computationally reconstructed using a fast Fourier transform. This imaging is validated using a cluster of ragweed pollen particles. Examples involving mineral-dust aerosols demonstrate the technique’s in situ imaging capability …

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Application Of Hyperspectral Vegetation Indices To Detect Variations In High Leaf Area Index Temperate Shrub Thicket Canopies, Steven T. Brantley, Julie C. Zinnert, Donald R. Young Jan 2011

Application Of Hyperspectral Vegetation Indices To Detect Variations In High Leaf Area Index Temperate Shrub Thicket Canopies, Steven T. Brantley, Julie C. Zinnert, Donald R. Young

United States Army: Publications

Accurate measurement of leaf area index (LAI), an important characteristic of plant canopies directly linked to primary production, is essential for monitoring changes in ecosystem C stocks and other ecosystem level fluxes. Direct measurement of LAI is labor intensive, impractical at large scales and does not capture seasonal or annual variations in canopy biomass. The need to monitor canopy related fluxes across landscapes makes remote sensing an attractive technique for estimating LAI. Many vegetation indices, such as Normalized Difference Vegetation Index (NDVI), tend to saturate at LAI levels >4 although tropical and temperate forested ecosystems often exceed that threshold. Using …

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Purification Of A Recombinant Heavy Chain Fragment C Vaccine Candidate Against Botulinum Serotype C Neurotoxin [Rbontc(HC)] Expressed In Pichia Pastoris, Michael P. Dux, Jicai Huang, Rick Barent, Mehmet Inan, S. Todd Swanson, Jayanta Sinha, John T. Ross, Leonard A. Smith, Theresa J. Smith, Ian Henderson, Michael M. Meagher Jan 2011

Purification Of A Recombinant Heavy Chain Fragment C Vaccine Candidate Against Botulinum Serotype C Neurotoxin [Rbontc(HC)] Expressed In Pichia Pastoris, Michael P. Dux, Jicai Huang, Rick Barent, Mehmet Inan, S. Todd Swanson, Jayanta Sinha, John T. Ross, Leonard A. Smith, Theresa J. Smith, Ian Henderson, Michael M. Meagher

United States Army: Publications

A purification process for the manufacture of a recombinant C-terminus heavy chain fragment from botulinum neurotoxin serotype C [rBoNTC(Hc)], a potential vaccine candidate, has been defined and successfully scaled-up. The rBoNTC(Hc) was produced intracellularly in Pichia pastoris X-33 using a three step fermentation process, i.e., glycerol batch phase, a glycerol fed-batch phase to achieve high cell densities, followed by a methanol induction phase. The rBoNTC(Hc) was captured from the soluble protein fraction of cell lysate using hydrophobic charge induction chromatography (HCIC; MEP HyperCel™), and then further purified using a CM 650M ion exchange chromatography …

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The Role Of Conflict Management On Virtual Team Performance And Satisfaction, Pilar Pazos, Anil Ustun, Rolando Delaguila Jan 2011

The Role Of Conflict Management On Virtual Team Performance And Satisfaction, Pilar Pazos, Anil Ustun, Rolando Delaguila

Engineering Management & Systems Engineering Faculty Publications

The role that input factors from project planning processes play on conflict emergence and conflict resolution in virtual teams is not well understood. Of particular interest for this paper is the role that factors during planning stages play in preventing interpersonal conflict, supporting conflict resolution and ultimately enhancing team outcomes in virtual team settings. This study examines the relationships among commitment to team goals, conflict management and team outcomes in virtual teams. First we provide an in depth review of relevant empirical findings. Next, we describe a study examining the relationships between three sets of variables: 1) goal commitment, 2) …

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Sysml Profiling For Handling Army Base Camp Planning, Dustin Nottage, Steven Corns Jan 2011

Sysml Profiling For Handling Army Base Camp Planning, Dustin Nottage, Steven Corns

Engineering Management and Systems Engineering Faculty Research & Creative Works

Army base camp planning is a complicated process involving many variables and optional facilities. the facilities can also vary in size and resource utilization depending on permanency of the base, local resources, and population on the base. Each level of facility is modeled and placed into a library database. All of these facilities must be distinguishable for planners to come in and export the correct facility based on the mission. the first method involves separating the different levels into packages so just the package could be exported. the issue is not all facilities will fit correctly. the second method is …

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Approximate Policy Iteration For Semi-Markov Control Revisited, Abhijit Gosavi Jan 2011

Approximate Policy Iteration For Semi-Markov Control Revisited, Abhijit Gosavi

Engineering Management and Systems Engineering Faculty Research & Creative Works

The semi-Markov decision process can be solved via reinforcement learning without generating its transition model. We briefly review the existing algorithms based on approximate policy iteration (API) for solving this problem for discounted and average reward under the infinite horizon. API techniques have attracted significant interest in the literature recently. We first present and analyze an extension of an existing API algorithm for discounted reward that can handle continuous reward rates. Then, we also consider its average reward counterpart, which requires an updating based on the stochastic shortest path (SSP). We study the convergence properties of the algorithm that does …

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Cognition Evolutionary Computation For System-Of-Systems Architecture Development, Feng Yang, Cihan Dagli, Weiping Wang Jan 2011

Cognition Evolutionary Computation For System-Of-Systems Architecture Development, Feng Yang, Cihan Dagli, Weiping Wang

Engineering Management and Systems Engineering Faculty Research & Creative Works

The evolving nature of system-of-systems requirements and corresponding architecture, and the complex causal relationship between the architecture of system-of-systems and its emergent behavior make the problem of system-of-systems architecture development a great challenge. as a tentative effort in meeting this special challenge, a new evolutionary computation paradigm- named Cognition Evolutionary Computation(CEC) is proposed, which models the creative cognition process of divergent and convergent thinking, adaptation and innovation, that drives the co-evolution of problem space, knowledge space and solution space. the optimization algorithm for CEC uses causal probabilistic network as the knowledge representation mechanism. a theoretical framework for CEC based system-of-system …

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Process Modeling System For Press Cure, Closed-Cavity Tooled Thick Composites, Arven H. Saunders Jan 2011

Process Modeling System For Press Cure, Closed-Cavity Tooled Thick Composites, Arven H. Saunders

Industrial, Manufacturing, and Systems Engineering Dissertations - Archive

Thick structural composite parts often use press curing with closed-cavity tooling for achieving dimensional tolerances. A commonly encountered defect for these parts is fiber waviness, whick limits its structural strength. The yield for such parts often suffers due to trial and error methods used to develop successful cure processes. In addition, yield for these parts suffers due to material variation. The objectives of this research were to: develop and validate a simplified yet practical cure process model for press cured thick composite parts, utilize the model in order to seek time-efficient optimized cure processes, investigate the effects of material variation …

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Improving Throughput And Predictability Of High-Volume Business Processes Through Embedded Modeling, Joseph S. Dekeyrel Jan 2011

Improving Throughput And Predictability Of High-Volume Business Processes Through Embedded Modeling, Joseph S. Dekeyrel

Electronic Theses and Dissertations

Being faster is good. Being predictable is better. A faithful model of a system, loaded to reflect the system's current state, can then be used to look into the future and predict performance. Building faithful models of processes with high degrees of uncertainty can be very challenging, especially where this uncertainty exists in terms of processing times, queuing behavior and re-work rates. Within the context of an electronic, multi-tiered workflow management system (WFMS) the author builds such a model to endogenously quote due dates. A WFMS that manages business objects can be recast as a flexible flow shop in which …

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Models For Evaluation Of Supply Chain Risk With Application To Healthcare Management, Ford Guangfu Zeng Jan 2011

Models For Evaluation Of Supply Chain Risk With Application To Healthcare Management, Ford Guangfu Zeng

Industrial, Manufacturing, and Systems Engineering Dissertations - Archive

Over the past two decades, supply chain management has come to be a key component of organization competitiveness and effectiveness. In the same period, most organizations have put a great deal of effort into improving their own and their supplier's supply chain performance. To a large extent, much of this effort has been aimed at improving the efficiency of supply chain operations. However, organizations have ignored or played down the risks from supply chain disruptions when developing supply strategies, which focus on cost reduction. It is proposed, therefore, that one such standard measure should measure the risk involved with organizations …

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Mathematical Optimization Techniques For Managing Selective Catalytic Reduction For Coal-Fired Power Plants, Passakorn Phananiramai Jan 2011

Mathematical Optimization Techniques For Managing Selective Catalytic Reduction For Coal-Fired Power Plants, Passakorn Phananiramai

Industrial, Manufacturing, and Systems Engineering Dissertations - Archive

Coal is one of the most important energy sources in the U.S. However, it is also one of the biggest air polluters where the major emissions generated from coal combustion are oxides of nitrogen (NOx). NOx leads to ozone formation and make people more susceptible to respiratory illness. The US Environmental Protection Agency (EPA) has steadily tightened the regulation for NOx emissions that can be discharged into the atmosphere. Many techniques and technologies can all assist with NOx removal. However, to meet upcoming EPA mandates, more aggressive technique such as Selective Catalytic Reduction (SCR) is highly recommended. SCR is an …

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Design Of The Layout Of A Manufacturing Facility With A Closed Loop Conveyor With Shortcuts Using Queueing Theory And Genetic Algorithms, Vernet Michael Lasrado Jan 2011

Design Of The Layout Of A Manufacturing Facility With A Closed Loop Conveyor With Shortcuts Using Queueing Theory And Genetic Algorithms, Vernet Michael Lasrado

Electronic Theses and Dissertations

With the ongoing technology battles and price wars in today's competitive economy, every company is looking for an advantage over its peers. A particular choice of facility layout can have a significant impact on the ability of a company to maintain lower operational expenses under uncertain economic conditions. It is known that systems with less congestion have lower operational costs. Traditionally, manufacturing facility layout problem methods aim at minimizing the total distance traveled, the material handling cost, or the time in the system (based on distance traveled at a specific speed). The proposed methodology solves the looped layout design problem …

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