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Full-Text Articles in Engineering

Characterization Of Time-Variant And Time-Invariant Assessment Of Suicidality On Reddit Using C-Ssrs, Manas Gaur, Vamsi Aribandi, Amanuel Alambo, Ugur Kursuncu, Krishnaprasad Thirunarayan, Jonathan Beich, Jyotishman Pathak, Amit Sheth May 2021

Characterization Of Time-Variant And Time-Invariant Assessment Of Suicidality On Reddit Using C-Ssrs, Manas Gaur, Vamsi Aribandi, Amanuel Alambo, Ugur Kursuncu, Krishnaprasad Thirunarayan, Jonathan Beich, Jyotishman Pathak, Amit Sheth

Publications

Suicide is the 10th leading cause of death in the U.S (1999-2019). However, predicting when someone will attempt suicide has been nearly impossible. In the modern world, many individuals suffering from mental illness seek emotional support and advice on well-known and easily-accessible social media platforms such as Reddit. While prior artificial intelligence research has demonstrated the ability to extract valuable information from social media on suicidal thoughts and behaviors, these efforts have not considered both severity and temporality of risk. The insights made possible by access to such data have enormous clinical potential - most dramatically envisioned as a trigger …


Maintaining Root Canal Curvatures After Preparation With Different Nickel-Titanium Rotary Systems (A Comparative In Vitro Study), Wael Betbout, Mohammad Al Shammaa, Roula S. Abiad May 2021

Maintaining Root Canal Curvatures After Preparation With Different Nickel-Titanium Rotary Systems (A Comparative In Vitro Study), Wael Betbout, Mohammad Al Shammaa, Roula S. Abiad

BAU Journal - Creative Sustainable Development

The ongoing advancement of materials and methods for root canal instrumentation is resulting in improved techniques with minimal variations to the canal morphology. One standard for assessment of the shaping quality of curved root canals is preparation-induced straightening of the canal. The aim of the study: To compare the effects of 2 Nickel-Titanium rotary systems, 2Shape (Micro-Mega, Besançon, France) and ProTaper Next (Dentsply,Sirona, Ballaigues, Switzerland), on maintaining the distobuccal canals curvature of extracted human maxillary molar teeth using periapical radiographs. Materials and methods: In this study a total of 26 distobuccal roots of upper maxillary molars were used and divided …


An Investigation On Non-Invasive Brain-Computer Interfaces: Emotiv Epoc+ Neuroheadset And Its Effectiveness, Md Jobair Hossain Faruk May 2021

An Investigation On Non-Invasive Brain-Computer Interfaces: Emotiv Epoc+ Neuroheadset And Its Effectiveness, Md Jobair Hossain Faruk

Symposium of Student Scholars

Neurotechnology describes as one of the focal points of today’s research around the domain of Brain-Computer Interfaces (BCI). The primary attempts of BCI research are to decoding human speech from brain signals and controlling neuro-psychological patterns that would benefit people suffering from neurological disorders. In this study, we illustrate the progress of BCI research and present scores of unveiled contemporary approaches. First, we explore a decoding natural speech approach that is designed to decode human speech directly from the human brain onto a digital screen introduced by Facebook Reality Laband University of California San Francisco. Then, we study a recently …


Strategies For Achieving The United States Health System's Quadruple Aim By Enhancing The Primary Care Level, Jennifer L. Mendoza-Alonzo May 2021

Strategies For Achieving The United States Health System's Quadruple Aim By Enhancing The Primary Care Level, Jennifer L. Mendoza-Alonzo

USF Tampa Graduate Theses and Dissertations

The quadruple aim is an approach to optimize the performance of the health system in the United States and consists of four dimensions. The main objective is to improve the population's health, followed by reducing cost, improving patients' experience, and increasing providers' satisfaction. In the present doctoral dissertation, I explore three strategies that help accomplish the quadruple aim at the primary care level. The analysis combines data science and operation research principles to address health system engineering questions.

Each strategy proposed in this document emphasizes one objective more than another; however, all of them in conjunction serve to attain the …


The Probability Of Success-Through Fault Tree Analytical Binomial Result, Tyleka Riddle May 2021

The Probability Of Success-Through Fault Tree Analytical Binomial Result, Tyleka Riddle

Night Flight: Online Literary Journal

Prestigious Appeal Rule of Thumb (Ear Drum Plugs)

In truant fashion, with proven accidental probabilistic perception for proposed cued facial expression recognition and voice commands without filtering. The estimated cost analysis for design and development generated from the enhanced project in the word "no”: Additionally, an audio noise effect size (ES) for desired level of comprehensive sensory receptors in sound reference to noisy party syndrome. Sytoss, (2019) "Resulting in a cocktail party theory for chalkboard distinction and conversation with applied facial recognition. As well as, the enhanced project management tool, EPMT, to provide output and input determination for higher-level acoustic …


Bibliometric Survey On Effect Of Socio-Economic Factors On Spread Of Corona Virus (Covid-19), Seema Patil Prof., Aayushi Verma Ms, Isha Patil Ms, Ravneesh Singh Mr, Raghav Gaur Mr May 2021

Bibliometric Survey On Effect Of Socio-Economic Factors On Spread Of Corona Virus (Covid-19), Seema Patil Prof., Aayushi Verma Ms, Isha Patil Ms, Ravneesh Singh Mr, Raghav Gaur Mr

Library Philosophy and Practice (e-journal)

The Novel Coronavirus disease has been rapidly spreading all around the globe, from the time when it was first reported in the Wuhan city of China. The primary focus of this bibliometric survey is to distinguish the documents which have hypothesized and expanded on the effects of various socio-economic factors when it comes to the spread of the Coronavirus.

This survey does the evaluation on the 480 documents found. The United Kingdom of the Great Britain and United States have contributed the largest number of publications in this field of research followed closely by India and Italy.

The survey includes …


Magnetic Resonance-Guided High Intensity Focused Ultrasound (Mrghifu) Induced Hyperthermia (Ht) For Treatment Of Cervical Cancer, Lifei Zhu May 2021

Magnetic Resonance-Guided High Intensity Focused Ultrasound (Mrghifu) Induced Hyperthermia (Ht) For Treatment Of Cervical Cancer, Lifei Zhu

McKelvey School of Engineering Graduate Student Theses & Dissertations

Hyperthermia (HT), which refers to increasing the temperature of the tumor tissue to 40–45°C for an extended period of time, has been reported to be one of the most effective sensitizers for radiation therapy (RT) and/or chemotherapy. High intensity focused ultrasound (HIFU) has been developed as a non-invasive and non-ionizing tool to induce localized HT. Magnetic resonance thermometry (MR thermometry) is one of the most reliable methods for non-invasively and precisely measuring the in vivo volumetric temperature in real time. The integration of MR thermometry with HIFU has been implemented in commercially available magnetic resonance guided high intensity focused ultrasound …


Subject-Specific Musculoskeletal Modeling Of Hip Dysplasia Biomechanics, Ke Song May 2021

Subject-Specific Musculoskeletal Modeling Of Hip Dysplasia Biomechanics, Ke Song

McKelvey School of Engineering Graduate Student Theses & Dissertations

Developmental dysplasia of the hip (DDH) is characterized by abnormal bony anatomy, causes pain and functional limitations, and is a prominent risk factor for premature hip osteoarthritis. Although the pathology of DDH is believed to be mechanically-induced, little is known about how DDH anatomy alters hip biomechanics during activities of daily living, partly due to the difficulties with measuring hip muscle and joint forces. Musculoskeletal models (MSMs) are useful for dynamic simulations of joint mechanics, but the reliability of MSMs for DDH research is limited by an accurate model representation of the unique hip anatomy. To address such challenges, this …


Impact Of Angiogenic And Osteogenic Factors In The Presence Of Biodegradable Piezoelectric Films, Jayla Millender May 2021

Impact Of Angiogenic And Osteogenic Factors In The Presence Of Biodegradable Piezoelectric Films, Jayla Millender

University Scholar Projects

One of the most common causes of bone graft rejection is lack of a vascular network connecting the graft to the existing native tissue – allowing for nutrient flow. Under current grafting techniques, the existing blood vessel network in the patient slowly invades the implant in order to supply the injured site with its necessary nutrients. The purpose of this research is to determine if a synthetic bone graft with a stable microvascular network can be developed in vitro. I hypothesize that the use of indirect angiogenic factors such as sonic hedgehog homolog and hypoxia-inducible factor-1 in combination with the …


Factors Associated With Mutations: Their Matching Rates To Cardiovascular And Neurological Diseases, Hannah B. Lucas, Ian Mcknight, Regan Raines, Abdullah Hijazi, Christoph Hart, Chan Lee, Do-Gyoon Kim, Wei Li, Peter H. U. Lee, Joon W. Shim May 2021

Factors Associated With Mutations: Their Matching Rates To Cardiovascular And Neurological Diseases, Hannah B. Lucas, Ian Mcknight, Regan Raines, Abdullah Hijazi, Christoph Hart, Chan Lee, Do-Gyoon Kim, Wei Li, Peter H. U. Lee, Joon W. Shim

Biomedical Engineering Faculty Research

Monogenic hypertension is rare and caused by genetic mutations, but whether factors associated with mutations are disease-specific remains uncertain. Given two factors associated with high mutation rates, we tested how many previously known genes match with (i) proximity to telomeres or (ii) high adenine and thymine content in cardiovascular diseases (CVDs) related to vascular stiffening. We extracted genomic information using a genome data viewer. In human chromosomes, 64 of 79 genetic loci involving >25 rare mutations and single nucleotide polymorphisms satisfied (i) or (ii), resulting in an 81% matching rate. However, this high matching rate was no longer observed as …


Automatic Data Collection System And Video Laryngoscope Database, Gabrielle Hoyer May 2021

Automatic Data Collection System And Video Laryngoscope Database, Gabrielle Hoyer

Utah Space Grant Consortium

The aggregate intubation data collected by a network of video laryngoscopes can be processed to understand the quality of an individual’s or a group of individual’s practice(s). Currently, all data surrounding intubations is self-reported and not understood on an aggregate basis. We are developing a technology which can enable monitoring and benchmarking of intubations across a wide variety of practices.


Predicting Propofol-Induced Burst Suppression Using An Individualized Model-Based Approach Over Repeated Treatments, Jason C. Huang May 2021

Predicting Propofol-Induced Burst Suppression Using An Individualized Model-Based Approach Over Repeated Treatments, Jason C. Huang

Utah Space Grant Consortium

Our group is investigating the antidepressant effects of high-dose propofol, but dosing propofol to induce standardized changes in EEG activity (“burst suppression”) is challenging due to limited knowledge of each subject’s pharmacokinetics (PK) and pharmacodynamics (PD). In this paper, we approximated PK-PD models for propofol-induced burst suppression (PIBS), based on multiple subjects over repeated treatments. We then applied these models to predict BSR in each subject’s repeated treatment, then evaluate their predictive performances. We hypothesized that predicting BSR from a greater number of previous treatments would improve performance, but our current results are not conclusive enough to validate the hypothesis. …


Machine Learning Applied To Colloidal Properties Of Perfluorocarbon Nanoemulsions For Imaging In Ards/Ali, Marco Hosfeld May 2021

Machine Learning Applied To Colloidal Properties Of Perfluorocarbon Nanoemulsions For Imaging In Ards/Ali, Marco Hosfeld

Electronic Theses and Dissertations

Acute Respiratory distress Syndrome (ARDS) and Acute Lung Injury (ALI) are inflammatory lung pathologies consisting of non-hydrostatic pulmonary edema leading to hypoxia and impaired gas exchange in the lungs. ARDS/ALI is both difficult to study and treat as it is not in itself a specific pathology but rather a syndrome consisting of many pathologies that vary case by case. It is, however, consistently characterized by an explosive acute inflammatory response in the lung parenchyma leading to hypoxia. Although time has seen to an increase in the understanding of ARDS/ALI, the mortality rate remains in the range of 30-50%. For these …


Is The Walking Pattern Similar Between Slope Walking And Obstacle Negotiation?, Jiani Lu May 2021

Is The Walking Pattern Similar Between Slope Walking And Obstacle Negotiation?, Jiani Lu

Theses & Dissertations

Studying biomechanical characteristics of human motion sheds light on the motor control strategies in the central nervous system. Slope walking and obstacle negotiation appear to have some similarities in control strategies based on subjective observation, but these two motions have never been compared objectively in biomechanics literature. This study aimed to investigate the similarities between obstacle negotiation and slope walking in kinematics and muscle activity. The similarities were determined by the correlation of the maximum heel elevation and muscle co-activation index between obstacle negotiation and inclined treadmill walking. The strength of correlation was compared in four different pairs of conditions: …


Pharyngeal Constriction As A Cause For Late Acquisition And Speech Sound Disorders Of Rhotic Sounds In English, Spanish, And French, Connor Mahon May 2021

Pharyngeal Constriction As A Cause For Late Acquisition And Speech Sound Disorders Of Rhotic Sounds In English, Spanish, And French, Connor Mahon

The Downtown Review: An Interdisciplinary Journal Written and Peer-Reviewed by Mandel Honors College Students at Cleveland State University

This paper attempts to explain why rhotic sounds are cross-linguistically late developing among the sound inventory of children. Included is a summary of the current literature regarding classification of rhotic sounds, an examination of the articulatory movement of the tongue root, and an overview of the clinical implications on the field of speech-language pathology. The evidence presented supports the hypothesis that pharyngeal constriction is characteristic of rhotic sounds in many languages, and that it is related to the relative late acquisition and higher rate of speech sound disorders, as seen in English, Spanish, and French.


Water Exchange Rate Across The Blood-Brain Barrier Is Associated With Csf Amyloid-Β 42 In Healthy Older Adults, Brian T. Gold, Xingfeng Shao, Tiffany L. Sudduth, Gregory A. Jicha, Donna M. Wilcock, Elayna R. Seago, Danny J. J. Wang May 2021

Water Exchange Rate Across The Blood-Brain Barrier Is Associated With Csf Amyloid-Β 42 In Healthy Older Adults, Brian T. Gold, Xingfeng Shao, Tiffany L. Sudduth, Gregory A. Jicha, Donna M. Wilcock, Elayna R. Seago, Danny J. J. Wang

Sanders-Brown Center on Aging Faculty Publications

INTRODUCTION: We tested if water exchange across the blood-brain barrier (BBB), estimated with a noninvasive magnetic resonance imaging (MRI) technique, is associated with cerebrospinal fluid (CSF) biomarkers of Alzheimer's disease (AD) and neuropsychological function.

METHODS: Forty cognitively normal older adults (67–86 years old) were scanned with diffusion‐prepared, arterial spin labeling (DP‐ASL), which estimates water exchange rate across the BBB (kw). Participants also underwent CSF draw and neuropsychological testing. Multiple linear regression models were run with kw as a predictor of CSF concentrations and neuropsychological scores.

RESULTS: In multiple brain regions, BBB kw was positively associated with CSF amyloid …


Collapsible Prosthetic Shower Leg, Amanuel Matias, Mahsa Ebrahim May 2021

Collapsible Prosthetic Shower Leg, Amanuel Matias, Mahsa Ebrahim

Honors Thesis

The purpose of this capstone project is to build a collapsible prosthetic shower leg that can provide a transtibial amputee with reliable support while showering. Phil Tamoush, an 83-year old transtibial amputee, was the inspiration for this work. Phil’s constant travel for his arbitration work leaves him without the option to bring along his usual shower leg due to the additional space it takes up in his travel bag. There are currently no commercially available prosthetic shower legs that can collapse into a condensed unit, so this capstone project explores an unexplored field for which there is a significant need. …


Understanding Of Aerosol Transmission Of Covid 19 In Indoor Environment - Part 2: Approaches To Mitigation, Adama Barro, Cathal O'Toole, Jacob S. Lopez, Matthew Quinones, Sherene Moore May 2021

Understanding Of Aerosol Transmission Of Covid 19 In Indoor Environment - Part 2: Approaches To Mitigation, Adama Barro, Cathal O'Toole, Jacob S. Lopez, Matthew Quinones, Sherene Moore

Publications and Research

The challenge we face in implementing solutions for new HVAC ventilation and filtration design, is to effectively improve air quality for virus mitigation without losing performance efficiency. The purpose of this improvement is to decontaminate the occupied enclosed areas, reducing the transmission of the corona virus aerosol transmission. Our research seeks reliable approaches to mitigate the further spread of aerosol transmission in indoor spaces. The methodology is to examine innovative HVAC engineering solutions that combat epidemiological problems of Covid-19 for the post-pandemic era, by researching scholarly articles and ASHRAE journals. We are achieving the goal of finding highly efficient resolutions …


Analysis Of Covid-19 Concerns Raised By The Construction Workforce And Development Of Mitigation Practices, Makram Bou Hatoum, Ali Faisal, Hala Nassereddine, Hadi Sarvari May 2021

Analysis Of Covid-19 Concerns Raised By The Construction Workforce And Development Of Mitigation Practices, Makram Bou Hatoum, Ali Faisal, Hala Nassereddine, Hadi Sarvari

Civil Engineering Faculty Publications

The coronavirus outbreak has created a global health crisis that has disrupted all industries, including the construction industry. Following the onset of the pandemic, construction workers faced and continue to face unprecedented safety and health challenges. Therefore, construction employers established new safety precautions to protect the health and safety of the workforce and minimize the spread of the virus. The new precautions followed the advice and guidelines offered by different health and safety agencies like the Occupational Safety and Health Administration (OSHA), Centers of Disease Control and Prevention (CDC), and the Associated General Contractors of America (AGC). With construction projects …


Rethink Everything 2: Markets, Globalization, Development, Nikhilesh Dholakia, Deniz Atik May 2021

Rethink Everything 2: Markets, Globalization, Development, Nikhilesh Dholakia, Deniz Atik

Markets, Globalization & Development Review

No abstract provided.


Glial Endothelial Brain Cell Co-Cultures For Testing Signaling Response And Delivery Of Novel Materials Across Blood Brain Barrier, Neela Prajapati May 2021

Glial Endothelial Brain Cell Co-Cultures For Testing Signaling Response And Delivery Of Novel Materials Across Blood Brain Barrier, Neela Prajapati

Master's Theses

The brain accounts for 20% of overall energy metabolism in the body though it just comprises 2% of the total body mass but has a limited capacity of storing energy unlike other critical organs in the body such as the heart and liver. This energy along with oxygen and nutrients is supplied by cerebral blood flow (CBF), any interruption of which can cease the brain function within seconds with a potential irreversible neuronal injury, within minutes. Vascular cells along with astrocytes and neurons are a part of a recently developed concept known as the Neurovascular Unit responsible for Neurovascular coupling …


Using Deep Learning To Analyze Materials In Medical Images, Carson Molder May 2021

Using Deep Learning To Analyze Materials In Medical Images, Carson Molder

Computer Science and Computer Engineering Undergraduate Honors Theses

Modern deep learning architectures have become increasingly popular in medicine, especially for analyzing medical images. In some medical applications, deep learning image analysis models have been more accurate at predicting medical conditions than experts. Deep learning has also been effective for material analysis on photographs. We aim to leverage deep learning to perform material analysis on medical images. Because material datasets for medicine are scarce, we first introduce a texture dataset generation algorithm that automatically samples desired textures from annotated or unannotated medical images. Second, we use a novel Siamese neural network called D-CNN to predict patch similarity and build …


Optimal Analytical Methods For High Accuracy Cardiac Disease Classification And Treatment Based On Ecg Data, Jianwei Zheng May 2021

Optimal Analytical Methods For High Accuracy Cardiac Disease Classification And Treatment Based On Ecg Data, Jianwei Zheng

Computational and Data Sciences (PhD) Dissertations

This work constitutes six projects. In the first project, a newly inaugurated research database for 12-lead electrocardiogram signals was created under the auspices of Chapman University and Shaoxing People's Hospital (Shaoxing Hospital Zhejiang University School of Medicine). This database aims to enable the scientific community in conducting new studies on arrhythmia and other cardiovascular conditions. In the second project, we created a new 12-lead ECG database under the auspices of Chapman University and Ningbo First Hospital of Zhejiang University that aims to provide high quality data enabling detection of the distinctions between idiopathic ventricular arrhythmia from right ventricular outflow tract …


Use Of 3d-Printed Surgical Spoons Compared To Other Cystotomy Methods In Dogs, Davina D'Angelo May 2021

Use Of 3d-Printed Surgical Spoons Compared To Other Cystotomy Methods In Dogs, Davina D'Angelo

Animal Science Undergraduate Honors Theses

Bladder stones, also known as uroliths, are not an uncommon condition in domestic dogs. To remove these uroliths, which occur in various sizes, shapes, and compositions, veterinarians will perform a surgical procedure called a cystotomy. A cystotomy consists of creating a small incision into the lumen of the urinary bladder and the utilization of various methods to extract the uroliths. For general veterinary practitioners, the laparoscopic-assisted technique is unavailable. As a result, the methods available for urolith extraction are often limited to flushing the stones out by inserting a urinary catheter through the urinary tract and the use of off-label …


Regression Analysis Of Pacing When Running A Marathon, Hawkin Starke May 2021

Regression Analysis Of Pacing When Running A Marathon, Hawkin Starke

Industrial Engineering Undergraduate Honors Theses

Regression analysis can be an effective way of examining performance in the marathon event. By splitting up the race into segments or in runner terminology “splits” the significance of each segment as it relates to the total finish time can be explored. Because the idea of splits is already ingrained into the minds of runners, it makes intuitive sense to use these as the metrics to define a race. Additionally, marathons generally make participant age and gender date publicly available which can then be used to find trends within specific demographics. This tailors trends to smaller groups of people, making …


Development Of A Wearable Finger Exoskeleton For Rehabilitation, Carlos Hernandez-Santos, Yasser A. Davizón, Alejandro Said, Rogelio Soto, L. C. Felix-Harran, Adriana Vargas-Martinez May 2021

Development Of A Wearable Finger Exoskeleton For Rehabilitation, Carlos Hernandez-Santos, Yasser A. Davizón, Alejandro Said, Rogelio Soto, L. C. Felix-Harran, Adriana Vargas-Martinez

Electrical and Computer Engineering Faculty Publications

This research work shows a new architecture of a novel wearable finger exoskeleton for rehabilitation; the proposed design consists of a one degree of freedom mechanism that generates the flexion and extension movement for the proximal, medial and distal phalange of the fingers to assist patients during the rehabilitation process, after neurological trauma, such as a stroke. The anatomy and anthropometric measures for the hand were used to define the design of the mechanism. In the analytic part, the representative equations for the forward and inverse kinematic analysis of the fingers are obtained, also a dynamic analysis is presented. The …


Engineering Controls For Bioaerosols In Non-Industrial/Non-Healthcare Settings, David Krause, Cheri Marcham, Bill Mele, Jack Springston, Rob Strode, Donald Weekes, Neil J. Zimmerman May 2021

Engineering Controls For Bioaerosols In Non-Industrial/Non-Healthcare Settings, David Krause, Cheri Marcham, Bill Mele, Jack Springston, Rob Strode, Donald Weekes, Neil J. Zimmerman

Publications

The list of disease pathogens that can be transmitted in the air is extensive. This list includes the common cold, SARS, measles, Hansen’s disease (leprosy), polio, influenza, Legionella (Legionnaires’ disease and Pontiac fever), and tuberculosis (TB). TB, SARS-CoV-1, avian influenza, varicella, and now SARS-CoV-2 all have received public notice due not only to their known or assumed ability to be transmitted in the air rapidly from one individual to another, but also for their virulence. Other bioaerosols that can be transmitted through the air include bacteria, fungal spores and fragments, dust mites, and pollen. This document was developed to address …


Design And Control Of A Peristaltic Pump To Simulate Left Atrial Pressure In A Conductive Silicone Model, Jeremy Collins May 2021

Design And Control Of A Peristaltic Pump To Simulate Left Atrial Pressure In A Conductive Silicone Model, Jeremy Collins

Mechanical Engineering Undergraduate Honors Theses

According to the CDC, atrial fibrillation is responsible for more than 454,000 hospitalizations and approximately 158,000 deaths per year. A common treatment for atrial fibrillation is catheter ablation, a process in which a long flexible tube is guided through the femoral artery and to the source of arrhythmia in the heart, where it measures the electrical potential at various locations and converts problematic heart tissue to scar tissue via ablation. This paper details the design and control of a low-cost ($400) peristaltic pump system using repetitive control to replicate blood pressure in the left atrium in a conductive silicone model …


Covid-19 Serological Diagnostic Development Using A Sars-Cov-2 Rbd Foldon Fusion, Joey Emery Breckenridge Jr. May 2021

Covid-19 Serological Diagnostic Development Using A Sars-Cov-2 Rbd Foldon Fusion, Joey Emery Breckenridge Jr.

Electronic Theses and Dissertations

Serological tests are conducted to assess humoral response against viral protein antigens, to assess viral exposure and protection from pathogens. The rapid development and modularity of serological assays have proven critical to managing the current SARS-CoV-2 pandemic. The receptor binding domain of SARS-CoV-2 is within the trimeric Spike protein and serves as a highly immunogenic target for potentially neutralizing antibodies. Current receptor binding domain serological assays use recombinant monomers or dimers of the receptor binding domain. The receptor binding domain is presented to the immune system natively in the context of the Spike protein trimer. Therefore, a recombinant trimeric receptor …


Electroencephalography Resting-State Networks In People With Stroke, Dylan B. Snyder, Brian D. Schmit, Allison S. Hyngstrom, Scott A. Beardsley May 2021

Electroencephalography Resting-State Networks In People With Stroke, Dylan B. Snyder, Brian D. Schmit, Allison S. Hyngstrom, Scott A. Beardsley

Biomedical Engineering Faculty Research and Publications

Introduction

The purpose of this study was to characterize resting-state cortical networks in chronic stroke survivors using electroencephalography (EEG).

Methods

Electroencephalography data were collected from 14 chronic stroke and 11 neurologically intact participants while they were in a relaxed, resting state. EEG power was normalized to reduce bias and used as an indicator of network activity. Correlations of orthogonalized EEG activity were used as a measure of functional connectivity between cortical regions.

Results

We found reduced cortical activity and connectivity in the alpha (p < .05; p = .05) and beta (p < .05; p = .03) bands after stroke while connectivity …