Engineering Commons^™

The Impact Of Nanopulse Treatment On The Tumor Microenvironment In Breast Cancer: Overturning The Treg Immunosuppressive Dominance, Anthony Nanajian

Biomedical Sciences Theses & Dissertations

Nanopulse treatment (NPT) is a high-power electric engineering modality that has been shown to be an effective local tumor treatment approach in multiple cancer models. Our previous studies on the orthotopic 4T1-luc breast cancer model demonstrated that NPT ablated local tumors. The treatment consequently conferred protection against a second live tumor challenge and minimized spontaneous metastasis. This study aims to understand how NPT mounts a potent immune response in a predominantly immunosuppressive tumor.

NPT changed the local and systemic dynamics of immunosuppressive cells by significantly reducing the numbers of regulatory T cells (Tregs), myeloid-derived suppressor cells (MDSCs), and tumor-associated macrophages …

Butte Reclamation Evaluation System Field Manual, Pioneer Technical Services, Inc.

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Experimental And Analysis Of Electromagnetic Characterization Of Biological And Non-Biological Materials In Microwave, Millimeter-Wave, And Terahertz Frequency Bands, Nagma Vohra

Graduate Theses and Dissertations

The goal of this research is to characterize the electromagnetic properties of biological and non-biological materials at terahertz (THz), millimeter-wave, and microwave frequency bands. The biological specimens are measured using the THz imaging and spectroscopy system, whereas the non-biological materials are measured using the microwave and millimeter-wave free-space system. These facilities are located in the Engineering Research Center at the University of Arkansas. The THz imaging system (TPS 3000) uses a Ti-Sapphire laser directed on the photoconductive antennas to generate a THz time domain pulse. Upon using the Fourier Transform, the spectrum of the pulsed THz signal includes frequencies from …

Developing A Lab-Scale Fluidized Bed Dryer System To Enhance Rough Rice Drying Process, Kaushik Luthra

Graduate Theses and Dissertations

For more than half of the world's population, rice (Oryza sativa L.) is a staple meal. However, rice growers encounter difficulties supplying this demand, particularly in developing nations, where rice is susceptible to spoilage if the moisture content is not lowered to a safe level soon after harvest. As a result, traditional drying methods, such as sun drying and natural air drying, are commonly used by rice growers, particularly in underdeveloped nations. However, these procedures are time-consuming and can lead to rice spoilage. On the other hand, fluidized bed drying is a well-established technology that might give rice growers a …

Nanomaterial-Based Biosensors For Detection Of Salmonella Typhimurium And Avian Influenza Virus H5n1 In Poultry, Xinge Xi

Graduate Theses and Dissertations

This research focused on developing biosensing method and biosensing device for rapid detection of pathogens in poultry: Salmonella Typhimurium and avian influenza virus H5N1. The first part of the dissertation reports an original research on the development of a portable biosensing device for Salmonella detection. The device was designed and constructed based on a previously developed optical biosensing method, using immuno-magnetic nanoparticles to specifically capture target bacteria, and immuno-quantum dot beads to label the target bacteria for fluorescence detection. All the actions of sample mixing, magnetic separation, and fluorescence detection were controlled automatically in a disposable microfluidic chip in the …

Impact Of Regional Climate Changes On Changes In River Water Content In Uzbekistan, A.T. Salokhiddinov, P.A. Khakimova, R.V. Toryanniova, O.A. Ashirova, A.G. Gofurov

Irrigation and Melioration

The paper presents the research results on the analysis of the climate change impacts on the potential of water resources in Central Asia. We analyzed the materials of an extensive database of monitoring data from numerous gauge stations on different river basins and satellite data information. A quantitative assessment of the transformation of river hydrographs, the growth of flow variability in the Republic of Uzbekistan's major rivers, in connection with climate change, was performed. The specific features of the impact of climate changes on changes in the water content of rivers in Uzbekistan in large and small river basins are …

Washing Technology For Medium And Highly Saline Soils, B.K. Saliev, M. S. Yuldashev, N.O. Shaimanov

Irrigation and Melioration

The article discusses the issues of conducting field experiments to assess the reclamation conditions of soils, which are a particular issue of managing salinity and water-salt regime, as well as increasing the efficiency of desalination. Today, 46.6% of the irrigated lands of the Republic of Uzbekistan have salinization of varying degrees, of which 30.9% are weak, 13.3% are moderate and 2.5% are highly saline. Medium and highly saline lands make up 15.8%. The essence of the proposed method of flushing from the traditional one is that in late autumn or winter, the collectors-ditches are closed, and the groundwater is artificially …

Distribution Of Calcium And Its Reserve Forms In Widespread Irrigated Gray Meadow Soils Of The Syrdarya Region, A. Akhatov

Irrigation and Melioration

The article examines the uneven distribution of calcium in reserve (general, potential, close and labile) forms in irrigated and gray-earth-meadow soils of the experimental section of the NIISSAVKH of the Gulistan district of the Syrdarya region and the farms "Sokhil" and "Ak altin" in irrigated meadow soils the form of a close reserve in the soil profile is 310 mg per 100 gr of soil. The upper layer of highly saline, medium loamy soil gradually decreases at a depth of 60-76 cm. layer. The labile calcium reserve in irrigated serozem-meadow, highly saline, medium loamy soils varies from 175 to 260 …

Design Of A Channel Straightening Route Using A Combined Dam With A Through Part Made Of Tetrahedra, M.R. Bakiev, A.B. Хаlimbetov, С.Э. Шукурова, I.J. Asamatdinov

Irrigation and Melioration

The design of the route when regulating riverbeds, the direction of the flow to the point of water intake will require solving some issues, including the amount of deviation of the dynamic axis of the flow, constrained by regulatory structures. The main purpose of this work is to develop a method for calculating the deviation of the dynamic axis of a flow that is one-way constrained by a combined dam, then through part of which is made of tetrahedra. The problem is realized using the Varignon theorem and the flow conservation equation written for the streamlines where the household state …

Improvement Of Informational-Methodological Provision On Foreign Languages For Teachers, G. Eshchanova

Irrigation and Melioration

The article discusses the innovative areas of activity, related to the use of information and communication technologies in the educational process of teachers in foreign languages in the world practice, the development of teachers professional communicative competence in teaching English, the use of information and communication, advanced pedagogical technologies in teaching to ensure the solution of such issues, as the increase in the level of development of foreign language skills, diagnostic technologies among teachers.

Дождеваsome Aspects Of Water Management In The Republic Of Uzbekistan During The Period Of Independence (Reality And Forecast), S. Khodjaev

Irrigation and Melioration

To date, there is no alternative to the introduction of the principles of integrated water resources management (IWRM), this is proved by the research of SIC ICWC on the territory of the South Fergana main canal, where the specific water supply per hectare of irrigated area has been reduced by 32% on an area of 120 thousand hectares, that is up to 7 thousand m³/ha, instead of the limited ones 10 thousand m³/ha. Researches recommend cutting off all types of collector-drainage waters (CDW) from the river trunks of the Aral Sea basin, including the Syr-Darya and Amu-Darya, since CDW are …

The Influence Of Gender Approaches On Education Efficiency, G. Eshchanova

Irrigation and Melioration

The given article covers the influence of gender approaches on education efficiency on the basis of statistical and scientific data, and the need to rely on the basis of the necessary knowledge for the ecologically sustainable development of women's knowledge, competence and entrepreneurship are shown. The educational process based on Gender differences and equality contributes significantly to the development of society.

Economic Assessment Of Factors Affecting The Decision Of Households To Engage In Non-Farm Activities, Sh.A. Muratov

Irrigation and Melioration

In this study, non-farm activities and their importance were studied, and it is analysed the influence of push and pull factors on the decision of family heads to engage in non-farm activities by Probit model regression. Furthermore, it is determined their elastic coefficients. The analysed data are collected by conducting an online survey from 134 respondents. The results are showed that the decision of family heads to engage in non-farm activities was greatly influenced by their gender, education, and number of family members, electricity supply, transport services, and size of their land. Namely, the decision of the head of the …

Somatic Inhibition By Microscopic Magnetic Stimulation, Hui Ye

Biology: Faculty Publications and Other Works

Electric currents can produce quick, reversible control of neural activity. Externally applied electric currents have been used in inhibiting certain ganglion cells in clinical practices. Via electromagnetic induction, a miniature-sized magnetic coil could provide focal stimulation to the ganglion neurons. Here we report that high-frequency stimulation with the miniature coil could reversibly block ganglion cell activity in marine mollusk Aplysia californica, regardless the firing frequency of the neurons, or concentration of potassium ions around the ganglion neurons. Presence of the ganglion sheath has minimal impact on the inhibitory effects of the coil. The inhibitory effect was local to the …

Identifying The Determinants And Extent Of Crop Diversification At Farm Level: A Case Study Of Uzbekistan, A.Э. Primov, M.H. Saidov, I. B. Rustamova, A.A. Abduvasikov

Irrigation and Melioration

Since independence, the government of Uzbekistan has implemented the number of agricultural policies such as making some crucial structural reforms at the farms, comprising different institutions and enhancing diversification of agricultural production in order to stabilize the agricultural sector of the country. Therefore, crop diversity has an important role in sustainable agriculture. We calculated the diversification index based on the Simpson Diversity Index method while ordinary least square (OLS) regression analysis was employed to assess the association of crop diversification on farm income using cross-sectional data from 381 farmers of Uzbekistan. The study revealed the mean computed Simpson Index values …

Flow Visualization And Aerosol Characterization Of Respiratory Jets Exhaled From A Mannequin Simulator, Sindhu Reddy Mutra

USF Tampa Graduate Theses and Dissertations

It is important to understand the airborne transmission of infectious diseases due to the COVID-19 pandemic. Physical experiments were conducted to understand the dispersion of aerosols emitted from a mannequin simulator replicating human tidal breathing through the nose and mouth with and without a protective face mask in an enclosed space. Flow patterns are observed via high-speed visualization, and the concentration and size distribution of the particles is measured as a function of distance from the mannequin using an optical particle sizer. Masks were shown to effectively reduce the horizontal dispersion of aerosol for both mouth and nose breathing. Further, …

Hypertrophic Cardiomyopathy Β-Cardiac Myosin Mutation (P710r) Leads To Hypercontractility By Disrupting Super Relaxed State, Alison Schroer Vander Roest, Chao Liu, Makenna M. Morck, Kristina Bezold Kooiker, Gwanghyun Jung, Dan Song, Aminah Dawood, Arnav Jhingran, Gaspard Pardon, Sara Ranjbarvaziri, Giovanni Fajardo, Mingming Zhao, Kenneth S. Campbell, Beth L. Pruitt, James A. Spudich, Kathleen M. Ruppel, Daniel Bernstein

Physiology Faculty Publications

Hypertrophic cardiomyopathy (HCM) is the most common inherited form of heart disease, associated with over 1,000 mutations, many in β-cardiac myosin (MYH7). Molecular studies of myosin with different HCM mutations have revealed a diversity of effects on ATPase and load-sensitive rate of detachment from actin. It has been difficult to predict how such diverse molecular effects combine to influence forces at the cellular level and further influence cellular phenotypes. This study focused on the P710R mutation that dramatically decreased in vitro motility velocity and actin-activated ATPase, in contrast to other MYH7 mutations. Optical trap measurements of single myosin molecules revealed …

Can Agricultural Management Induced Changes In Soil Organic Carbon Be Detected Using Mid-Infrared Spectroscopy?, Jonathan Sanderman, Kathleen Savage, Shree R.S. Dangal, Gabriel Duran, Charlotte Rivard, Michel A. Cavigelli, Hero T. Gollany, Virginia L. Jin, Mark A. Liebig, Emmanuel Chiwo Omondi, Yichao Rui, Catherine Stewart

Agricultural and Environmental Sciences Faculty Research

A major limitation to building credible soil carbon sequestration programs is the cost of measuring soil carbon change. Diffuse reflectance spectroscopy (DRS) is considered a viable low-cost alternative to traditional laboratory analysis of soil organic carbon (SOC). While numerous studies have shown that DRS can produce accurate and precise estimates of SOC across landscapes, whether DRS can detect subtle management induced changes in SOC at a given site has not been resolved. Here, we leverage archived soil samples from seven long-term research trials in the U.S. to test this question using mid infrared (MIR) spectroscopy coupled with the USDA-NRCS Kellogg …

Modeling The Effect Of Igg Subclasses And Specificity In The Translocation Of Monoclonal Antibodies Across The Placental Barrier, Sayuri Tais Miyamoto Magnabosco

ENGS 88 Honors Thesis (AB Students)

Infections are responsible for over half a million neonatal deaths every year (Lawn et al., 2014). Thus, there is huge interest in leveraging maternal immunization against infectious diseases to grant fetal protection during its development through the vertical transferring of IgG antibodies, the only Ig subclass that can significantly cross the placental barrier. Studies about vertical immunization rely on in-vitro models to extrapolate physiological conditions of the human placenta. The BeWo Transwell model (Bode et al., 2006) presents itself as a reliable model to mimic the transplacental transport mechanism of antibodies (Ellinger et al., 1999; Poulsen et al., 2009) …

End-Breakages Of Carded Ring-Spun Yarns., Rizk El-Bealy, S. Ibrahim, Ismail Rakha

Mansoura Engineering Journal

In the present work, the rate of end-breakages during the spinning of carded yarns 20 Nm up to 50 Nm from Egyptian (Giza 75) cotton fiber have been observed. The phenomenon has been investigated considring the effect of twist, draft, spindle speed, traveller weight and doffing position. The experiments were carried out by varying two-variables at different levels and three-variables using 33 factorial design technique. The results declared that the end-breakage rate was found to be influenced significantly by: twist, draft, spindle speed and doffing position. In addition to the above parameters, the two-factor interaction such as spindle speed with …

Flash Radiotherapy: Skin Pigmentation As A Non-Invasive Indicator For Radiation-Induced Damage, Brady Mccallister

ENGS 88 Honors Thesis (AB Students)

FLASH ultra-high dose rate radiotherapy (RT) is one of the most rapidly growing subfields of radiation oncology today due to its potential to increase the limits of the therapeutic ratio. The FLASH effect, which includes heightened normal tissue sparing paired with iso-effective tumor cell killing, has been literature documented, in a limited manner, in rodent models, a few large animals, and one clinical patients.

A porcine-based experiment was conducted to test the effects of FLASH RT on normal tissue compared to conventional (CONV) RT. A clinical linear accelerator (LINAC) was reversibly converted to be capable of FLASH RT. A female …

Splitting The Scatter: Distinguishing Marine Organisms From Oceanographic Structures Using Acoustic Monitoring, Zhen Lu, Daisuke Hasegawa, Takahiro Tanaka, David M. Spencer, Yuji Okazaki, Takeshi Okunishi

Journal of Marine Science and Technology–Taiwan

In the northwest Pacific Ocean, off the Sanriku coast of Japan, convergence between the Tsugaru Warm Current (TWC) and the cold Oyashio Current (OC) results in the formation of highly dynamic oceanographic features that promote high biodiversity and generate hotspots for a range of commercially important fisheries. However, their effects on local biodiversity over much smaller spatiotemporal scales ( < 1 km) remains unclear. With the development of acoustic technology in recent years, echo-sounders are increasingly being used to conduct high-precision fishery resource assessments and detect small-scale variability in the oceanic thermohaline structure. In this study, we conducted a simultaneous hydrographic and dual-frequency echo-sounder survey to discriminate oceanographic features and marine organisms in the TWC-OC confluence zone. Echograms of acoustic backscatter measured at 38 kHz detected similar oceanographic features that were obtained from our hydrographic survey observations, but these features were less pronounced in the 120 kHz echograms. The dynamic oceanographic structure in the TWC-OC zone returned a large amount of backscatter, making it difficult to identify marine organisms from the scatter. The frequency differences of volume backscattering strength (SV) were, however, able to distinguish oceanographic structures from zooplankton detections. Outcomes from this study highlight the difficulty of distinguishing between hydrographic and biological detections in dynamic oceanographic environments. Further research into the acoustic frequency characteristics of heterogeneous hydrographic features will help better understand how species distributions are affected, so that the acoustic method can be used to provide more accurate estimates of species abundance.

Fine-Scale Vertical Movements And Behavior Of Immature Skipjack Tuna (Katsuwonus Pelamis) Off Eastern Taiwan, Wei-Chuan Chiang, Takayuki Matsumoto, Shian-Jhong Lin, Qi-Xuan Chang, Michael K. Musyl, Yuan-Shing Ho, Fumio Ohta

Journal of Marine Science and Technology–Taiwan

Skipjack tuna are globally distributed in tropical and temperate seas but little is known about their fine-scale diving patterns and how fish size and (or) maturity influences patterns off eastern Taiwan. A total of 211 immature skipjack (36 e 47 FL cm) in the study were caught by trolling near subsurface fish aggregating devices (FADs) near Green Island (southeastern Taiwan) and were tagged with Lotek LAT-2910 archival tags. The low rate of recovery (2.4%) suggests a high post-release mortality but this low rate could also be consistent with large population sizes, dispersal, tag loss or uncooperative fishers. Five individuals were …

Evaluating The Fish Aggregation Effect Of Wind Turbine Facilities By Using Scientific Echo Sounder In Nanlong Wind Farm Area, Western Taiwan, Ting-Chieh Huang, Hsueh-Jung Lu, Jia-Rong Lin, Shih-Hsuan Sun, Kou-Wei Yen, Jing-Yi Chen

Journal of Marine Science and Technology–Taiwan

During the stages of construction and operation of the wind power facilities, fishery and fishery resources in the wind farm areas will certainly be changed greatly. One of the major concern is the aggregation effect of wind turbines facility. We use scientific echo sounder together with scuba diving to survey fish aggregations in the wind farm areas. In order to obtain echoes very near the facility, we use tilt beam angle instead of traditional vertical one. Variation of target strength varies while using tilted beam angle were discussed both by ex-situ and in-situ experiment. In ex-situ experiment, we measured TS …

Site Fidelity And Return Trips Of Visually And Olfactorily Inhibited Black Rockfish (Sebastes Schlegelii) Individuals Tracked By Acoustic Telemetry, Mitsuki Kuroda, Yoshinori Tatsu, Yuya Ueda, Hokuto Shirakawa, Kenji Minami, Kazushi Miyashita, Makoto Tomiyasu

Journal of Marine Science and Technology–Taiwan

For fish of the genus Sebastes, which have strong site fidelity, understanding the characteristics of their return trips and how their sensory cues influence behavior will be useful for conservation and resource management. Here, we conducted a behavioral tracking study for the black rockfish Sebastes schlegelii using acoustic telemetry and sensory inhibition. We compared aspects of the return process for individuals in a control group (CNT), and fish in blind (BLD) and olfactory inhibition (OLF) conditions. Nine individuals were released 850 m from the fishing site, and all of them returned. However, the time taken to complete the return varied, …

Geospatial And Acoustic Application In An Artificial Reef Site Of South Korea, Myounghee Kang, Rina Fajaryanti, Kyounghoon Lee, Eun-A Yoon, Woo-Seok Oh, Eunbi Min, Young-Jae Shin, Yong-Suk Choi, Byung-Ho Yi, Hui Zhang, Doojin Hwang

Journal of Marine Science and Technology–Taiwan

Artificial reefs are important since they provide additional habitat leading to increasing abundance and biomass of marine biota. In a Bukchon artificial reef, Jeju Island, South Korea, environment data, artificial reef properties, and acoustic data in four seasons were integrated to visualize and examine their connections using a geographic information system (GIS). As a result, regarding the spatial and temporal distributions of fishes, January had the lowest Nautical Area Scattering Coefficient (NASC, m2/nm2) and June had the highest NASC, and relatively high NASC was observed from 5 to 30 m deep throughout seasons. The influential circle (effective distance from reef) …

Computational Prediction Of Mutagenesis In Glycine Max Rubisco Activase Monomer For Increased Thermal Stability, Catherine B. Emanuel, Hamza Haq '21, Vasanth Ramesh '21, Jaden Wang '21, Angela Ahrendt, Sarah Stainbrook

Student Publications & Research

No abstract provided.

Real-Life Conundrums In The Struggle For Institutional Transformation, Julia Mcquillan, Nestor Hernandez

Department of Sociology: Faculty Publications

Intersecting systems of inequality (i.e., gender and race/ethnicity) are remarkably resistant to change. Many universities, however, seek National Science Foundation Institutional Transformation awards to change processes, procedures, and cultures to make science, technology, engineering, and mathematics (STEM) departments more inclusive. In this article we describe a case study with observations for eight years of before (2000–2007), five during (2008–2013), and seven after (2014–2020) intensive efforts to increase women through reducing barriers and increasing access to women. Finally, we reflect on flawed assumptions built into the proposal, the slow and uneven change in the proportion of women over time, the strengths …

Development Of A Portable Low-Moisture Food Pasteurization Device Using Rf Heating, Eric Jason Ohata

Master's Theses

Bacterial presence in low-moisture foods such as flour, cereals, baby formula, and spices, have become a concern due to sanitizing challenges. The food industry currently focuses on wet food sanitation as opposed to low-moisture foods because of bacteria’s inability to reproduce in low water activity media. Traditionally, food processing RF heating pasteurizes in mass quantities while an equivalent consumer device does not exist the market today. A consumer product would help eliminate food waste by providing an easy way to sanitize food and extend shelf life. The Portable Food Pasteurization (PFP) project is an interdisciplinary project involving the Electrical Engineering, …

High Performance Mixed-Matrix Electrospun Membranes For Ammonium Removal From Wastewaters, Shu-Ting Chen, Sumith Ranil Wickramasinghe, Xianghong Qian

Chemical Engineering Faculty Publications and Presentations

Mixed-matrix electrospun membranes were developed to investigate ammonium removal from low ammonium concentration wastewaters for the first time. Particles derived from the inexpensive zeolite 13X were successfully incorporated into polyethersulfone (PES) matrices. The fabricated mixed-matrix electrospun membranes demonstrate high ammonium removal capacity reaching over 55 mg/g_zeolite, more than 2.5 times higher than the previously fabricated mixed-matrix membranes via non-solvent induced phase inversion. Moreover, the membranes fabricated exhibit high permeability and ease of regeneration. Over 90% of total ammonium nitrogen (TAN) can be removed from low TAN wastewaters such as aquaculture wastewaters. In addition to zeolite 13X, other zeolite …