Engineering Commons^™

Improving The Stimulation Selectivity In The Human Cochlea By Strategic Selection Of The Current Return Electrode, Ozan Cakmak

Dissertations

The hearing quality provided by cochlear implants are poorly predicted by computer simulations. A realistic cochlear anatomy is crucial for the accuracy of predictions. In this study, the standard multipolar stimulation paradigms are revisited and Rattay’s Activating Function is evaluated in a finite element model of a realistic cochlear geometry that is based on µ-CT images and a commercial lead. The stimulation thresholds across the cochlear fibers were investigated for monopolar, bipolar, tripolar, and a novel (distant) bipolar electrode configuration using an active compartmental nerve model based on Schwartz-Eikhof-Frijns membrane dynamics. The results suggest that skipping of the stimulation point …

Angiogenic Supports For Microvascular Engineering, Zain Siddiqui

Dissertations

Ischemic tissue disease is caused by a lack of circulation / blood supply to tissue. This can be treated by introducing a number of angiogenic (pro-blood vessel forming) factors into the tissue. This work presents strategies for ischemic tissue treatment utilizing a novel proangiogenic self-assembling peptide hydrogel platform. To demonstrate the utility of this platform, its use alone as an angiogenic therapeutic (both alone as a self-assembling hydrogel and with two-component systems), and its ability to vascularize implants is explored. Due to these angiogenic scaffolds demonstrating efficacy to regenerate microvasculature, this work evaluates diseases that can be treated by the …

Urban Farming: Empowerment To Increase Economic, Education, And Nutritional Benefit For The Sub-Urban Community, Nasruddin Nasruddin, Yusuf Donner Dwiyantama, Banu Muhammad, Anom Bowalaksono, Dian Ayubi, Sarah Islamiati Pertiwi

ASEAN Journal of Community Engagement

This article discusses the urban farming program at Sekolah Master in Beji, Depok, Indonesia, which aims to provide the community with broader benefits, such as economy, education, and increased nutritional value. The project involves planting method that was introduced to this school community. The program itself consists of several stages, starting from the preparation—dissemination of the program and designing a plan for the greenhouse, the implementation—constructing the greenhouse and installing the automatic water system, planting the vegetation, and monitoring and evaluation of the program. Eventually, an evaluation of the successful program is required to determine whether the program can be …

Ex-Ante Cost-Benefit Analysis Of High-End And Low-Cost Wireless Sensor Network (Wsn) Technology Packages For Efficient Irrigation Water Management In The Philippines, Marielle Q. Aringo, Victor B. Ella, Camille G. Martinez, Gamiello S. Pereira

Journal of Economics, Management and Agricultural Development

Four wireless sensor network (WSN) technology packages developed for efficient irrigation water management in the Philippines were subjected to ex-ante cost-benefit analysis (CBA) to assess their financial viability. The WSN technologies include high-end and low-cost wireless sensors for upland crop production with drip irrigation system and lowland crop production with alternate wetting and drying (AWD). Results showed that the high-end WSN technology packages are only viable for high-value crops such as red onion, bell pepper, and hot pepper. The low-cost WSN technology packages are viable for all selected crops except sweet corn. Minimum areas were also generated for each crop …

Isolation And Characterization Of Cellulose Degrading Microorganisms Generating Electricity Using Microbial Fuel Cell, Lama Fayad, Rania Amer, Ahmad Abd El Nabi, Ali Hammoud, Hoda Yusef

BAU Journal - Science and Technology

Global warming and the accumulation of organic waste constitute a serious environmental problem. Therefore, microbial fuel cells (MFC) are an eco-friendly device that have significant capability for the production of electricity using biodegradable waste as fuel. Microorganisms used as catalysts in the anode compartment, execute a principal function in operating MFCs. The present study was conducted to isolate and to screen potential bioelectricity generating microorganisms from dumpsite soil samples and also to construct a domestic dual-chambered microbial fuel cell (MFC). Streptomyces fimicarius was found to be the best isolate for the degradation of cellulose and the production of bioelectricity. The …

Multipolymer Microsphere Delivery Of Sars-Cov-2 Antigens, Farah Shahjin, Milankumar Patel, Jatin Machhi, Jacob D. Cohen, Mohammad Ullah Nayan, Pravin Yeapuri, Chen Zhang, Emiko Waight, Mahmudul Hasan, Mai Mohamed Abdelmoaty, Prasanta K. Dash, You Zhou, Irene Andreu, Howard E. Gendelman, Bhavesh D. Kevadiya

Nebraska Center for Biotechnology: Faculty and Staff Publications

Effective antigen delivery facilitates antiviral vaccine success defined by effective immune protective re- sponses against viral exposures. To improve severe acute respiratory syndrome coronavirus-2 (SARS-CoV- 2) antigen delivery, a controlled biodegradable, stable, biocompatible, and nontoxic polymeric micro- sphere system was developed for chemically inactivated viral proteins. SARS-CoV-2 proteins encapsulated in polymeric microspheres induced robust antiviral immunity. The viral antigen-loaded microsphere sys- tem can preclude the need for repeat administrations, highlighting its potential as an effective vaccine.

A Review On Nanomaterials And Nanohybrids Based Bio-Nanocomposites For Food Packaging, Kalpani Y. Perera, Amit K. Jaiswal, Swarna Jaiswal

Articles

With an increasing demand for a novel, eco-friendly, high-performance packaging material “bio-nanocomposites” has attracted great attention in recent years. The review article aims at to evaluating recent innovation in bio-nanocomposites for food packaging applications. The current trends and research over the last three years of the various bio-nanocomposites including inorganic, organic nanomaterials, and nanohybrids, which are suitable as food packaging materials due to their advanced properties such as high mechanical, thermal, barrier, antimicrobial, and antioxidant are described in detail. In addition, the legislation, migration studies, and SWOT analysis on bio-nanocomposite film have been discussed. It has been observed that the …

Weakly-Supervised Learning Method For The Recognition Of Potato Leaf Diseases, Junde Chen, Xiaofang Deng, Yuxin Wen, Weirong Chen, Adnan Zeb, Defu Zhang

Engineering Faculty Articles and Research

As a crucial food crop, potatoes are highly consumed worldwide, while they are also susceptible to being infected by diverse diseases. Early detection and diagnosis can prevent the epidemic of plant diseases and raise crop yields. To this end, this study proposed a weakly-supervised learning approach for the identification of potato plant diseases. The foundation network was applied with the lightweight MobileNet V2, and to enhance the learning ability for minute lesion features, we modified the existing MobileNet-V2 architecture using the fine-tuning approach conducted by transfer learning. Then, the atrous convolution along with the SPP module was embedded into the …

Chitosan Oligosaccharides As A Nanomaterial Platform: Biological Properties And Applications In The Biomedical And Pharmaceutical Fields, Muhamad Alif Razi

Makara Journal of Science

Chitosan oligosaccharides (COS) have been introduced as marine-derived biomaterials with potential health benefits and good water solubility properties. This study presents an overview of the promising nanomaterial platform for biomedical and pharmaceutical applications of COS. The health benefits of COS, primarily their antioxidant and protective effects, anti-inflammatory activity, antidiabetic properties, and cholesterol-lowering effects are discussed. Furthermore, the promising recent articles on specific topics such as drug delivery systems and nanobiomaterials, are highlighted

The Role Of The Neurodevelopmental Disorder Gene Myt1l In Mammalian Brain Development, Jiayang Chen

Arts & Sciences Electronic Theses and Dissertations

Recent human genetic studies have associated mutations in a gene called Myelin Transcription Factor 1 Like (MYT1L) with neurodevelopmental disorders (NDDs). Patients with MYT1L loss of function (LoF) mutations (MYT1L Syndrome patients) demonstrate shared symptoms such as microcephaly, attention deficit and hyperactivity disorder (ADHD), and obesity. Despite prior studies showing MYT1L overexpression facilitates neuronal differentiation in vitro, its functions in vivo, especially in the mammalian brain, and how its mutation leads to human disease pathology remains poorly understood. Here, I established the first mouse model of MYT1L Syndrome mimicking a patient specific LoF mutation. I found mice with Myt1l heterozygous …

Indicadores De Sustentabilidad Vba Mesmis, Geovanny Andres Martinez Jimenez

Ciencias Administrativas, Económicas y Contables

El presente libro se ha diseñado con el propósito de que el lector tenga una experiencia satisfactoria al momento de emplear los indicadores VBA MESMIS. Por tanto, el documento se estructura de manera minuciosa en dos apartados; el primero que trata acerca de los criterios de diagnóstico, en el que se plantea un ejemplo con información de tres unidades productivas, con el fin de i) desarrollar los indicadores correspondientes a los criterios; ii) conocer el nivel de desempeño de los indicadores; iii) realizar un análisis general y proponer recomendaciones para el fortalecimiento de la sustentabilidad de las unidades productivas; en …

Towards Structured Planning And Learning At The State Fisheries Agency Scale, Caleb A. Aldridge

Theses and Dissertations

Inland recreational fisheries has grown philosophically and scientifically to consider economic and sociopolitical aspects (non-biological) in addition to the biological. However, integrating biological and non-biological aspects of inland fisheries has been challenging. Thus, an opportunity exists to develop approaches and tools which operationalize planning and decision-making processes which include biological and non-biological aspects of a fishery. This dissertation expands the idea that a core set of goals and objectives is shared among and within inland fisheries agencies; that many routine operations of inland fisheries managers can be regimented or standardized; and the novel concept that current information and operations can …

Synthesis Of Novel Chiral Phosphorothioic Acid Organocatalysts And Application To Synthetic Methodology, Parsa Azaei

Undergraduate Research Symposium Posters

Much research efforts have been centered towards the synthesis of novel Bronsted acid catalysts. These organocatalyst enable synthesis of natural products, pharmaceuticals, and bioactive small molecules under toxic-metal-free conditions by donating their protons, while not being consumed in the reaction. Chiral phosphorothioic acid have significant potential as novel organocatalysts due to their high modifiability of chirality and acidity under environmentally friendly conditions; however, synthesis of these organocatalysts are far and in between. Therefore, our research aimed to i) synthesize novel phosphorothioic acid organocatalysts and ii) to apply these novel catalysts toward new methodology development.

Evaluation For Using Expended Bioelectrochemical Systems As Soil Amendments For Improved Corn Plant Growth And A Drought Resistant Soil., Jackson Lee Sauers

Theses and Dissertations

A long-held practice is to mix agricultural soil with a soil amendment to improve growing conditions in crops. A common soil amendment is biosolids produced from both municipal and dairy wastewater due to the macro- and micronutrients within it. Both the agricultural and wastewater industries are participating in the Circular Economy concept (CEC). Two experiments explored using expended bioelectrochemical systems (BES) that treated either synthetic dairy wastewater (DWW) or synthetic municipal wastewater (SWW) as soil amendments to improve corn plant growth when treated with three different nutrient treatments: 100%- 50%- and 0% Hoagland Nutrient Solutions. Biochar and used terracotta clay …

Performance Analysis: Using The Northern Sea Route As An Alternative To Traditional Routes, Liangkun Xu, Qing Yu

Journal of Marine Science and Technology

The grounding accident of M/V EVER GIVEN in the Suez Canal causes a catastrophic loss on shipping companies. Alternatively, previous studies have presented encouraging findings of the remarkable benefits of time and cost saving in the Northern sea route (NSR) due to extend the ice-free time and shorten the distance. Ships using the NSR could shorten as much as 40% of the sailing distance from China (Shanghai) to Europe (Rotterdam) compared with the traditional route via the Suez Canal. This paper investigates the economic potential of using the NSR as a cost-effective route in comparison with Suez Canal Route (SCR) …

Numerical And Approximate Analytic Solutions Of Second- Order Nonlinear Boundary Value Problems, Chein-Shan Liu, Jian-Hung Shen, Yung-Wei Chen

Journal of Marine Science and Technology

The shooting method consists of guessing unknown initial values, transforming a second-order nonlinear boundary value problem (BVP) to an initial value problem and integrating it to obtain the values at the right end to match the specified boundary condition, which acts as a target equation. In the shooting method, the key issue is accurately solving the target equation to obtain highly precise initial values. Due to the implicit and nonlinear property, we develop a generalized derivative-free Newton method (GDFNM) to solve the target equation, which offers very accurate initial values. Numerical examples are examined to show that the shooting method …

Optimization Of Circular Silencers Internally Hybridized With Multiple Reverse Chambers Using The Ga Method, Min-Chie Chiu, Ying-Chun Chang, Tian-Syung Lan, Ho-Sheng Chen

Journal of Marine Science and Technology

A noise abatement method using an eigen function in conjunction with an optimizer (Genetic Algorithm) under a space-constrain situation is proposed in this study concerning a high order wave propagation effect. An eigen function is used to describe an acoustical field and shorten the acoustical model in a four-pole transfer matrix form. The system’s four-pole matrix estimates the Transmission Loss (TL) for the silencers by multiplying individual four-pole matrices.

Additionally, a case study of an air compressor’s broadband noise elimination is introduced. Three types of circular reverse silencers (silencers A-C) internally hybridized with multiple straight chambers are adopted to efficiently …

Numerical Investigation Of The Uncertainty Of Typhoon Wave Parameters Retrieval Using Hf Radar, Toan Duy Dao, Hwa Chien

Journal of Marine Science and Technology

The aim of this study was to identify the sources of uncertainties of typhoon wave field monitoring using HF radar and to quantitatively assess the bias of the wave parameters, such as significant wave height and mean period, retrieved under various conditions. The strategy was to apply a purely numerical simulation of the Doppler-range spectra and then compare the estimation results to the target. For the quantitative investigation, a numerical test-bed was established. The test-bed was used to simulate the Doppler spectra based on Barrick’s (1972) theory by using the input of the directional wave spectra. The typhoon wave spectra …

A Fused Data Based Real-Time Collision Warning System For Ferries In The Yangtze River, Xiaojia Liu, Ke Zhang, Han Xue, Yingtang Li

Journal of Marine Science and Technology

The risks for ferries in the Yangtze River are relatively high, as they frequently cross the main traffic flows, leading to more intersections with other upwards and downwards ships. Although some studies have developed many models to assess collision risks in the Yangtze River, collision warning studies on ferries are scant. Meanwhile, most of the current collision studies evaluate risk based on AIS data, which are incapable of providing real-time ship information as they are discrete-time series data. In this work, fused data combining radar and AIS data are applied in a real-time ship collision warning model to assess the …

Experimental Study Of The Effect Of A Solid Wing Conveyor On Marine Debris Collection, Erik Sugianto, Jeng-Horng Chen

Journal of Marine Science and Technology

Marine debris is a global problem that has not been resolved. This has encouraged the emergence of marine debris cleaning technologies, one of which is a conveyor ship. However, how effective conveyors are in collecting waste has not been studied. In this paper, experimental research on conveyors as marine debris collectors is investigated. The capability of catamarans with or without solid wing conveyors to collect marine debris is explored. Three kinds of marine debris collection models are used: no-wing conveyor, a 12.5-cm-long wing conveyor, and an 18.75-cm-long wing conveyor. Artificial marine debris (AMD) is spread on the water surface in …

Solving Nonlinear Boundary Value Problems With Nonlinear Integral Boundary Conditions By Local And Nonlocal Boundary Shape Functions Methods, Chein-Shan Liu, Yung-Wei Chen, Jian-Hung Shen

Journal of Marine Science and Technology

The paper considers the second-order nonlinear boundary value problem (NBVP), which is equipped with nonlinear integral boundary conditions (BCs). Two novel iterative algorithms are developed to overcome the difficulty of NBVP with double nonlinearities involved. In the first iterative algorithm, two nonlocal shape functions incorporating the linear integral terms are derived, and a nonlocal boundary shape function (NBSF) is formulated to assist the solution. Let the solution be the NBSF so that the NBVP can be exactly transformed into an initial value problem. The new variable is a free function in the NBSF, and its initial values are given. For …

Nanoclays And Curcumin Based Food Packaging Material For Intelligent Food Packaging Applications, Kalpani Y. Perera, Swarna Jaiswal, Amit K. Jaiswal, Shubham Sharma

Articles

Bionanocomposite packaging eco-friendly alternatives with enhanced characteristics. This study aimed to develop a bionanocomposite intelligent packaging. Sodium alginate, gelatin, Curcumin (Cur), glycerol, and Nanoclay (NC) films were prepared. The influences of nanoclay and curcumin on the surface, optical, mechanical, chemical, barrier, and pH-indicating properties were studied. The results showed that the lightness of films was reduced by 1.28 folds compared to NC (control) film, while the yellowness of films increased by 5.82 folds. Film transparency was reduced by 9.3 folds and a 3.46 folds increase in UV barrier properties was observed compared to NC (control) film. The highest tensile strength …

Clove Essential Oil And Nanoclays-Based Active Food Packaging, Kalpani Y. Perera, Shubham Sharma, Amit K. Jaiswal, Swarna Jaiswal

Articles

Active food packaging materials enhance the shelf-life of food products while reducing food waste. The current study aims to develop a biodegradable active food packaging material. The food packaging material was developed with the incorporation of clove essential oil, sodium alginate, gelatin, and nanoclay films were prepared. The influences of nanoclay and clove on the surface, optical, mechanical, chemical, barrier, and pH-indicating properties were studied. The lightness and yellowness increased by 1.06 folds and 3.34 folds when compared to clove (control), respectively. The UV barrier property 0.08±0.01nm in all films, while 8.37 folds reduction in transparency has been observed as …

Cold Plasma Technology In Food Packaging, Kalpani Y. Perera, Jack Prendeville, Amit K. Jaiswal, Swarna Jaiswal

Articles

Cold plasma (CP) is an effective strategy to alter the limitations of biopolymer materials for food packaging applications. Biopolymers such as polysaccharides and proteins are known to be sustainable materials with excellent film-forming properties. Bio-based films can be used as an alternative to traditional plastic packaging. There are limitations to biopolymer packaging materials such as hydrophobicity, poor barrier, and thermos-mechanical properties. For this reason, biopolymers must be modified to create a packaging material with the desired applicability. CP is an effective method to enhance the functionality and interfacial features of biopolymers. It etches the film surface allowing for better adhesion …

2022 - The Third Annual Fall Symposium Of Student Scholars

Symposium of Student Scholars Program Books

The full program book from the Fall 2022 Symposium of Student Scholars, held on November 17, 2022. Includes abstracts from the presentations and posters.

Microbial Ecology Of Urban Sewers, Emily Lou Lamartina

Theses and Dissertations

Municipal sewage provides a glimpse into the health and activities of a human society. For more than a century, sewage exploration has helped expose the sources of disease outbreaks and track disease progression over time. Recent advancements in wastewater surveillance born from the COVID-19 pandemic have potential to enhance mitigation efforts against the decades-long global health crisis of microbial antibiotic resistance. However, critical knowledge gaps exist in wastewater surveillance, stemming from a lack of understanding in sewer microbial ecology. Ecology reveals trends in how communities respond and adapt to change, which has far-reaching implications for identifying effective strategies for disease …

Using Molecular Dynamics Simulations To Decipher Mechanistic Details Of Biomolecular Processes Of Biology And Biotechnology Oriented Applications, Adithya Polasa

Graduate Theses and Dissertations

Researchers in chemistry and biology often utilize computer simulations, in conjunction with experimental data, to model and predict the structures, energies, kinetics, processes, and functions of the systems that are their focus of study, ranging from single molecules to whole viruses. Here, we use molecular dynamics (MD) techniques to gain a deeper understanding of biomolecular processes in biology and biotechnology-oriented applications. Using a mixture of equilibrium and non-equilibrium MD simulations, this work describes the insertion process of YidC at the atomic level. In order to better comprehend the insertion process, several docking models of YidC-Pf3 in the lipid bilayer were …

Out Of The Wood: Sojurn Cyclery, Jay H. Kinsinger

Engineering and Computer Science Faculty Contributions to the Popular Press

No abstract provided.

Deciphering The Firing Patterns Of Hippocampal Neurons During Sharp-Wave Ripples, Kourosh Maboudi Ashmankamachali

Theses and Dissertations

The hippocampus is essential for learning and memory. Neurons in the rat hippocampus selectively fire when the animal is at specific locations - place fields - within an environment. Place fields corresponding to such place cells tile the entire environment, forming a stable spatial map supporting navigation and planning. Remarkably, the same place cells reactivate together outside of their place fields and in coincidence with sharp-wave ripples (SWRs) - dominant electrical field oscillations (150-250 Hz) in the hippocampus. These offline SWR events frequently occur during quiet wake periods in the middle of exploration and the follow-up slow-wave sleep and are …

Evaluating The Viscoelastic Properties Of Alligator Skin Gelatin, Alligel, Compared To Mammalian And Fish Gelatins, Sarah E. Jimenez

Honors Theses

No abstract provided.