Engineering Commons^™

Ionic Liquid Pilocarpine Serves As Therapeutic Cosolvent And Permeation Enhancer For Glaucoma Medication, Ashish Trital, Lei Xu, Burhan Ates, Tzu Chen Wang, Vimalin Mani, Hu Yang

Chemical and Biochemical Engineering Faculty Research & Creative Works

The efficacy of hydrophobic ocular drugs is significantly hindered by their low bioavailability, for which poor water solubility is a major contributing factor. In this work, we synthesized pilocarpine-derived ionic liquid [Pilo-OEG] Cl (PO) and evaluated its cosolvent properties for the codelivery of the hydrophobic antiglaucoma drug brimonidine (BM) for glaucoma therapy. Pilocarpine was quaternized with 2-[2-(2-chloroethoxy) ethoxy] ethanol in a one-pot reaction to yield PO, and its structure was confirmed using ¹H NMR and FT-IR spectroscopy methods and further characterized for its rheological property and thermal stability. The HET-CAM assay and cell viability study showed that PO was …

Predicting Tart Cherry Stem Water Potential Using Uav Multispectral Imagery And Environmental Data Via Symbolic Regression, Anderson L. S. Safre, Alfonso Torres-Rua, Kurt Wedegaertner, Brent Black, Brennan Bean, Burdette Barker, Matt Yost

Civil and Environmental Engineering Faculty Publications

Tart cherry is an important fruit crop in Utah, where irrigation is essential due to arid conditions. Precision irrigation requires reliable indicators of plant water status, and stem water potential (Ψ_stem), is among the most sensitive though labor-intensive and spatially limited. This study develops Ψ_stem estimation models using high-resolution multispectral Unmanned Aerial Vehicle (UAV) imagery combined with meteorological and soil moisture data, applying Symbolic Regression (SR). Results show a stronger correlation between optical bands and Ψ_stem during the pre-harvest period. Among 85 vegetation indices, the Red Chromatic Coordinate (RCC) index performed best (R² = 0.67). …

Redesigning Online Graduate Orientation To Foster Academic Resilience And Prevent Underperformance, Stella Michael-Makri, David E. Rodriguez

Journal of Academic Underperformance

Graduate students in fully online programs often begin their academic journey without adequate preparation for the emotional, structural, and cultural challenges of graduate-level work. For students who are first-generation, racially marginalized, international, or returning to education after time away, this lack of scaffolding can lead to early disengagement, underperformance, or attrition. Orientation, often treated as a checklist of logistical tasks, represents a missed opportunity for meaningful academic intervention. This manuscript proposes a five-module conceptual model for online graduate orientation designed to proactively support online graduate students in the domains of emotional regulation and academic identity, time management and executive functioning, …

The Wildlife Intelligence For Aviation Safety (Wild-Ai), Bao Khoa Tran

Student Research Symposium (SRS)

Wildlife strikes pose a significant safety risk and economic burden to the aviation industry. Over 291,000 strikes have been reported in the U.S. since 1990, causing an estimated $248 million in annual losses. The Wild-AI (Wildlife Intelligence for Aviation Safety) project leverages cutting-edge technologies, including large language models (LLMs), machine learning (ML), explainable AI (XAI), and Unmanned Air Vehicles (UAV) imagery, to enhance wildlife hazard management at airports. Wild-AI transforms traditional Wildlife Hazard Assessments (WHAs) by integrating advanced data analytics and UAV monitoring. By utilizing historical wildlife-strike data and ML algorithms, we will identify key predictors of damaging strikes, such …

When Irl Is Not An Option: Social Media Bans And The Exclusion Of Autistic Youth, Melanie Gruben, Ashley Sheil, Anne Ryan Duffy, Jacob Camillleri, Michelle O'Keeffe, Hazel Murray

Women+ in Early Career Research Symposium

After the roll-out of the social media ban in Australia in 2025, policy makers are considering psychosocial benefits and logistical implications. However, the needs of autistic people, who may rely more on the Internet for social connection earlier in life, should be taken into account. This white paper proposes a responsibility to support alternative means of social connection for autistic young people where bans are considered, as IRL (in real life) socialising is not always accessible.

Selfhealth: Continuous Semantic Intelligence For Privacy-Aware Lifelogging, Allie Tran

Women+ in Early Career Research Symposium

Lifelogging — the continuous digital recording of everyday experience through wearable cameras and sensors — has long promised benefits for memory augmentation, health monitoring, and lifestyle analysis. However, current systems follow a capture–store–retrieve model that delays analysis until after data collection, limiting their practical usefulness and creating significant privacy risks through prolonged retention of sensitive raw data. This paper argues that lifelogging should instead analyse data at the moment of capture, enabling timely, context-sensitive support and safer handling of personal information through privacy-by-design. We demonstrate the feasibility of this approach through SelfHealth, an early prototype system built on a custom …

Fiber Optic Polarimetric Stress Sensor Improvements, Maxwell R. Richter, Max Randall, Mark C. Harrison

Engineering Faculty Articles and Research

The progression of diseases such as cancer has been correlated with tissue stiffness. For example, breast cancer tissue has been found to be stiffer than healthy mammary tissue. At present, stiffness measurement devices are not suitable for nondestructive, high-resolution measurements on small, delicate samples. We report a compact, portable, and sensitive fiber optic stress sensor that overcomes many of these limitations and is suitable for soft materials such as tissue. We demonstrate several improvements to a previous fiber stress sensor in physical hardware, software, and data analysis. We have designed and fabricated a custom enclosure to shield the sensitive setup …

Physical And Chemical Study Of Interaction In The Urea–Valine System For The Creation Of Modified Liquid Nitrogen Fertilizers, Suvonkul Erkhanovich Nurmonov, Saydullo Khamidovich Azimov

Chemical Technology, Control and Management

This study reports the results of a comprehensive physicochemical investigation of the urea–L-valine binary system, conducted to validate its potential as a modified base for liquid nitrogen fertilizers.

By utilizing the methods of isomolar series, visual-polythermal analysis, X-ray phase (XRD) and single-crystal X-ray diffraction (SC-XRD), synchronous thermal analysis (TGA/DTA), and FT-IR spectroscopy, it was determined that the interaction between components in both aqueous solutions and the solid phase results in the formation of molecular associates stabilized by hydrogen bonds, without the formation of new stoichiometric compounds.

The concentration and temperature limits of the system's stability were defined, revealing a reduction …

Self-Aware Quantum-Inspired Routing Framework For 6g And Quantum Networks, Haitham M. Abdelghany, Mohamed M. Ashour

Mansoura Engineering Journal

This paper introduces a quantum-hybrid-aware routing framework that incorporates the concepts of quantum computing with meta-cognitive learning to improve adaptability, reliability, and awareness in dynamic quantum networks. The proposed system accommodates a new IoT, edge computing and 6G system, where routing schemes should be flexible and robust and have cross-topology functionality. Conventional methods of quantum reinforcement learning can be characterized by a trade-off between exploration and decision stability. To cope with this, the proposed self-aware hybrid architecture is a combination of quantum-enhanced learning and a meta-cognitive awareness layer to allow autonomous agents to monitor performance and adjust routing strategies on …

The Effect Of Polyester And Lycra Loop Lengths On The Recovery Properties Of Single Jersey Knitted Fabrics, Abdelmonem Fouda, Moaaz Eldeeb

Mansoura Engineering Journal

Knitted fabrics are well known for their comfort due to their ability to elongate in the wale direction at the expense of the course direction, and vice versa. However, they lack dimensional stability, especially single jersey knitted fabrics. To address this issue, Lycra threads have recently been incorporated into their production to improve shape recovery after stress is released. Despite this enhancement, the fabric does not fully return to its original shape, highlighting the need to measure this phenomenon accurately. This study aims to firstly: simulate the production of a frame designed to measure the recovery and elongation of knitted …

Cultivation Of Arthrospira Platensis (Spirulina) In Food-Based Industrial Wastewater For High-Yield Phycocyanin Extraction, Pavithira Sathinathan

Student Works (2020-2029)

Arthrospira platensis (Spirulina) is a filamentous cyanobacterium valued for its nutritional profile, particularly the pigment–protein phycocyanin, with potent antioxidant and anti-inflammatory properties. Despite its industrial significance, large-scale commercialization remains constrained by high cultivation costs and inefficient extraction methods. This study investigated the use of food-based industrial wastewater as an alternative nutrient medium for Spirulina cultivation, aiming to reduce production costs, enhance phycocyanin yield, and support sustainable wastewater remediation. Three types of food-based wastewater with different nutrient composition (WW1, WW2, WW3) was diluted with Kosaric medium (1:1) and used for Spirulina cultivation. The highest biomass concentration was achieved in WW2 (1.93 …

Sustainable Aviation Fuel (Saf) From Used Cooking Oil (Uco) In Egypt: Opportunities And Challenges., Lamiaa Abdallah

Mansoura Engineering Journal

Global aviation sector contributes nearly 2.5% of global CO2 emissions. Aviation is hard-to-decarbonize sector due to the high energy densities required for aircraft. Commercial aviation is fueled by kerosene-based jet fuel. Alternatives for this carbonbased fuel include electric batteries, hydrogen fuel, and SAF. Electric batteries have very low energy densities. Hydrogen would require a complete change of the aviation system, including fuel & airport infrastructure. SAF is the only viable option in the short to medium term. SAF is produced from sustainable feed-stocks (like agricultural oils), with no embodied carbon. Existing airplanes can use traditional fuel blended with up to …

Optimized Deep Learning Framework With H2o For Lung Cancer Prediction, Walaa Hassan Ibrahim, Mohamed S. Saraya, Sally M. Elghamrawy, Ali I. Eldesouky

Mansoura Engineering Journal

The automatic diagnosis of lung cancer using chest X-ray (CXR) images has significantly advanced with progress in computing, machine learning, and deep learning. However, detecting lesions and nodules remains challenging due to CXR limitations. Early lung cancer detection is critical for successful treatment, but current AI algorithms often rely on large annotated datasets, which are not always available. To address this, a novel multi-classification deep learning framework is proposed that combines CXR and CT images. This approach leverages the detailed feature detection capabilities of CT scans alongside the complementary views from CXRs, improving early-stage lung cancer detection and classification precision. …

Physiological And Neurological Impact Of Biophilic Design In Architectural Design Studios: A Case Study Of King Salman International University, Islam Ashraf Mohamed, Alaa El-Eishy, Marwa A. Soliman

Mansoura Engineering Journal

Biophilic design integrates nature into architecture to enrich sensory and cognitive experiences, enhance psychological well-being, and improve performance. This study explores its physiological and neural effects in design studios at King Salman International University through an experimental methodology combining theoretical review and lab-based investigation. Tools included electrocardiography (ECG) for heart rate variability (HRV), eye-tracking for visual attention, and the Self-Assessment Manikin (SAM) for emotional evaluation. Nine participants viewed five digital architectural scenes with varying biophilic integration. Direct nature connections elicited greater visual attention, pleasure, and perceived control, indicating higher engagement and relaxation.  A scene lacking biophilic elements led to reduced …

Rapid Single-Cell Measurement Of Transient Transmembrane Water Flow Under Osmotic Gradient, Hong Jiang, Jinnawat Jongkhumkrong, Y. J. Chao, Qian Wang, Guiren Wang

Faculty Publications

Aquaporins (AQPs) are critical for transmembrane water transport in response to osmotic gradients, but their gating and regulatory mechanisms remain poorly understood. A central challenge is the lack of methods to measure water flow across AQPs from individual cells with the spatiotemporal resolution and sensitivity equivalent to patch-clamp recordings of ion fluxes—a limitation stemming from the electrically silent nature of water flow. Here, we present a novel optical technique—Flow-Induced Fluorescence Increase Velocimetry (FIFIV) based on Laser-Induced Fluorescence Photobleaching Anemometry (LIFPA)—that enables direct, real-time monitoring of cytoplasmic flow induced by transmembrane water transport under osmotic pressure gradients. Using small molecular fluorescent …

Population Satisfaction Indicators Of The Quality-Of-Life Standards During The Work Trip (A Case Study Of The Cities Of Minia And New Minia), Shimaa Mohammed Hamdy Derbala, Amna Waz Amgad Ali

Mansoura Engineering Journal

The research examined the indicators of population satisfaction with the quality of life during work trips in the cities of Minia and New Minia, in relation to the problem of low urban communication between the two cities and the continued dependence of debtors on each other to provide employment opportunities. The research examined previous studies linking the quality of life of work trips to the environmental, social and psychological aspects of the movement and economy, A questionnaire was designed for a sample of the population (388 individuals) to assess the residents' impression of the quality of life during their work …

Isolated Bacillus Licheniformis Sp01 From Daqing Oilfield In Reducing Chromium(Iii) Crosslinked Polymer Residue And Enhancing Oil Recovery, Xiao Hui

Student Works (2020-2029)

After polymer gel formation, the residual partially hydrolyzed polyacrylamide (HPAM) and the crosslinker (Cr3+) caused plugging and decreased oil recovery. Microorganisms can degrade HPAM to address the issues, but Cr³⁺ inhibits the process and reduces oil recovery. This study explores the underexamined biodegradation of HPAM and improved oil recovery in the presence of Cr³⁺, offering new perspectives for microbial enhanced oil recovery (MEOR) after polymer gel formation. HPAM and crude oil were innovatively used as the sole nitrogen(N) and carbon(C) sources to isolate the best-growing strain from Daqing Oilfield produced water, identified as Bacillus licheniformis SP01. The oil displacement potential …

Strategies For Sustainable And Inclusive Outdoor Wayfinding In Healthcare Facilities: An Approach To Enhance User Experience At Kafr Alsheikh University Hospital, Egypt, Rania Abd Allateef Ghanam, Ahmed Salah El-Deep

Mansoura Engineering Journal

Outdoor wayfinding plays a critical role in shaping user experience in healthcare environments, where inadequate navigation can heighten stress and hinder timely access to care. Despite the presence of wayfinding systems in many hospitals, outdoor navigation remains underexamined and inconsistently addressed in design guidelines. This study fills this gap by investigating architectural strategies to enhance outdoor wayfinding and reduce user stress. The research focuses on Kafrelsheikh University Hospital in Egypt and applies a twophase methodology: (1) a comprehensive literature review to identify current principles, guidelines, and best practices in outdoor wayfinding, and (2) an on-site case study to assess existing …

The Impact Of Integrating Social Benefit Requirements For Urban Green Infrastructure And Place Identity Attributes To Enhance The Sense Of Place - Case Study Of Central Park, Madinaty, New Cairo City, Egypt, Ibrahim Magdi Mohammed, Rehab Abdelfatah Abdel Aziz Mahmoud

Mansoura Engineering Journal

This research develops an integrated model that links the social benefit requirements of Urban Green Infrastructure (UGI) with the non-physical attributes of Place Identity (PI) to enhance the Sense of Place (SOP) in contemporary urban environments. The need for this integration arises from limitations in current planning frameworks, which often prioritize ecological performance while overlooking cultural, perceptual, and behavioral dimensions that shape user attachment and belonging. The study adopts an inductive and synthesis-based approach to identify key UGI indicators across environmental, social, economic, and spatial dimensions, alongside PI attributes related to places’ legibility, uniqueness, publicness and territoriality, place’s identification. To …

Enhancing Thermal Energy Storage Efficiency Using Optimized Concrete Materials: A Review, Ahmed Mohamed Abbass, Ahmed M. El-Khayatt, Khaled A. Eltawil

Mansoura Engineering Journal

The increasing global energy demand and the environmental impact of fossil fuels necessitate the development of sustainable energy solutions. Solar energy is a promising alternative, but its intermittency and inefficiency limit its widespread adoption. This study explores the role of advanced concrete-based thermal energy storage systems in addressing these challenges. Key aspects examined include packing density optimization, high-temperature performance, and hydrothermal durability of concrete. The research highlights the importance of granulometric optimization, binder selection, and hydration mechanisms in enhancing concrete properties. Additionally, the effects of heat exposure on concrete durability, permeability, and mechanical strength are analyzed, with a focus on …

Optimized Thermal Management Of Cylindrical Lithium-Ion Batteries Using Circular Fins And Forced Air-Cooling, Mohamed M. Donia, Ahmed A. Hegazi, Mohamed A. Aziz, Osama Abdelrehim

Mansoura Engineering Journal

The Battery Thermal Management System (BTMS) is vital for maintaining the optimal performance, safety, and longevity of electric vehicle batteries by keeping their temperature within a desired range. This study proposes an optimized cooling solution for BTMS based on both experimental and numerical investigations. Experimental tests were performed on a single battery cell under discharging rates of 1C, 2C, 3C, and 4C using an electronic load, with thermal performance evaluated under natural convection. Numerical models simulating both forced and natural convection were developed using ANSYS 19.3, and a combined Computational Fluid Dynamics (CFD) and Response Surface Methodology (RSM) approach was …

Verification Of Offline Signature Based On A Hybrid Dense-Attention-Residual-Cnn Structure Optimized By Grey Wolf Algorithm, Zeyad T. Salim, Mahmoud M. Saafan, Eman M. El-Gendy

Mansoura Engineering Journal

Signature verification is a necessary vision task with prevalent use in securing realworld applications. Offline signature is a popular type that needs to efficacious approach to be checked due to the depending on the paper time and the written tool. The progress in intelligent algorithms participates in supporting simple way authentication-based signatures. In this research work, an offline signature verification (OSV) based on an optimized and costumed convolutional neural network(CNN) infrastructure is suggested. The CNN is costumed by integrating residual, dense, and attention mechanisms, then optimized by applying a grey wolf optimization(GWO) algorithm. The system is trained and tested with …

Protecting ‘Punks’: The Shortcomings Of The Prison Rape Elimination Act, Rachel Goldsmith

Binghamton University Undergraduate Journal

Prisoner-on-prisoner sexual abuse is widespread in US male prisons, with inmates “turning each other out” by sexually assaulting each other. While the Prison Rape Elimination Act (PREA) received unanimous support in Congress in 2003, motivated by the Human Rights Watch Report “No Escape: Male Rape in Prisons,” scholars argue that the PREA fails to protect prisoners from prison rape: for example, its standards may be ineffective or criminalize consensual sex between prisoners. This essay will examine the shortcomings of the PREA, drawing on current legal scholarship, and propose solutions to enhance the law's effectiveness in protecting prisoners. The US government …

Prediction Of Thyroid Disease Based On Machine Learning Algorithms, Tuqa Ahmed Elbillihy, Eman Abdelhalim, Mohamed Ashour, Hala B. Nafea

Mansoura Engineering Journal

Accurately diagnosing thyroid disease remains a challenge in medicine, necessitating the use of reliable computational techniques for early detection and categorization. Using a dataset of 3164 patient records, this study applies machine learning algorithms to create a computer-aided thyroid disease diagnosis system. The data set includes demographic information, clinical indicators, and thyroid function test results. To improve model performance, the study focuses on preprocessing approaches such as data cleaning, normalization, and feature selection. The use of feature engineering techniques to determine the most predictive characteristics associated with thyroid problems is highlighted. Five machine learning classifiers—Random Forest, K-Nearest Neighbors, Support Vector …

Seismic Behavior Of Slender Cable-Supported Braced Frame Structures, Aya Aboelnaga, Mohamed Mortagi, Mohamed E. El Madawy, A.H.A. Abdelrahman, M. Naguib

Mansoura Engineering Journal

This research investigates advanced strategies to enhance the seismic performance and global stability of slender steel frames by integrating cable-supported and braced systems. To address these challenges, the study develops finite element (FE) models of multi-story slender frames in SAP2000, incorporating both cable-supported configurations and diagonal bracing systems. Nonlinear time-history analyses are performed using selected earthquake ground motions to evaluate structural response, inter-story drift, and mode shape behavior. Results highlight the efficiency of cablesupported frames in controlling lateral displacements and redistributing forces, while also emphasizing the role of bracing in providing additional stiffness. The findings demonstrate that guided frames with …

Neuproio: A Dual-Action Solid Drug Nanoparticle Topical Formulation For Simultaneous Intraocular Pressure Reduction And Neuroprotection For Glaucoma, Lei Xu, Mu Li, Lin Qi, Tzu Chen Wang, Dong Liu, Vimalin Jeyalatha Mani, Hsin Yin Chuang, Qingbo Yang, Ruipu Mu, Samira Mahdi, Da Huang, Honglan Shi, Yang Hu, Hu Yang

Chemical and Biochemical Engineering Faculty Research & Creative Works

Glaucoma is a leading cause of irreversible blindness, primarily due to elevated intraocular pressure (IOP) that damages the retina and optic nerve. Most topical glaucoma treatments focus solely on IOP-lowering without direct neuroprotection, as drug delivery to the posterior eye is challenging. Here, we developed NeuProIO, a dual-action solid drug nanoparticle (NP) eye drop for simultaneous IOP reduction and neuroprotection. Using flash nanoprecipitation in a multi-inlet vortex mixer, we fabricated the first NeuProIO solid drug NPs incorporating the repurposed neuroprotective agent maprotiline (MAP) and the IOP-lowering agent betaxolol (BX), forming MAP/BX NPs for synergistic glaucoma treatment. The NeuProIO improved stability …

Advanced Design Topics For The Engineering Of Agricultural And Mechanical Equipment, Robert M. Stwalley Iii, Roger Tormoehlen

Purdue University Press Books

Off-road equipment designs contend with some unusual challenges and environmental conditions that are not seen by standard on-road vehicles. Advanced Design Topics for the Engineering of Agricultural and Mechanical Equipment offers design topic reviews related to areas that need special consideration within off-road applications. CAN-BUS systems, soil compaction, composite bearings, field welding practices, and weld strength in bending applications are examined, among other subjects. Providing comprehensive coverage of these matters with the current state-of-the-art technologies and best practices as they relate to equipment design for the agricultural, construction, forestry, and mining industries, this book is well-aligned with collegiate advanced agricultural …

Mechanized Tube Well Installation, Robert M. Stwalley Iii, Grace L. Baldwin Kan-Uge, Roger Tormoehlen

Purdue University Press Books

Mechanized Tube Well Installation provides detailed information on the design development of a mechanized means to install shallow tube wells using a hydraulic driver attached to a small vehicle. This book explores the creation of this technique through the merging of available components, selection of the components, testing of the assembly, and the driving of wells. It also provides comprehensive coverage of state-of-the-art engineering, technology, and best practices as they relate to driving water wells for human consumption, animal care, and irrigation. Mechanized Tube Well Installation is well-aligned with collegiate humanitarian aid, environmental and natural resources engineering, and agricultural equipment …

A Proposed Vision To Activate Smart Urban Growth Concepts For The New Egyptian Cities, Nirman M. El-Sayed, Mamdouh A. Al-Minshawi

Mansoura Engineering Journal

Smart urban growth is the ideal solution to urban problems within the cities of the fourth generation in Egypt, and despite this, most of them depend on traditional urban thought without activating "Smart Urban Growth", which is known to maintain lands from deterioration and make societies suitable for living and providing the necessary services. The goal of research to set standards to activate smart urban growth as a thought that keeps pace with sustainable urban development and Egypt's 2030 vision, work to use the global smart cities approach and how they reach intelligence. While the research follows the "analytical" deductive …

Finding Research Datasets And Evaluating Data Quality, Ibis Anette Moreno-Lozano Phd.

Day Family Research Lab Workshop Series

No abstract provided.