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Articles 1651 - 1680 of 5708
Full-Text Articles in Engineering
Electrochemical Surface-Enhanced Raman Spectroscopic Studies On Nickel Ultramicroelectrode, Li-Wen Wu, Wei Wang, Yi-Fan Huang
Electrochemical Surface-Enhanced Raman Spectroscopic Studies On Nickel Ultramicroelectrode, Li-Wen Wu, Wei Wang, Yi-Fan Huang
Journal of Electrochemistry
Nickel (Ni) electrodes are widely used in electrochemical researches. Understanding electrochemical processes on Ni electrodes through in-situ characterization of adsorbed species on their surfaces is helpful for rational optimization and application of Ni electrochemistry. Microelectrochemical surface-enhanced Raman spectroscopy (μEC-SERS) combines the mass transfer feature of ultramicroelectrode with high-sensitivity characterizations of molecular structures, which is a powerful method for studying Ni electrochemistry on polarization and non-equilibrium conditions. The key point of performing μEC-SERS is to make a SERS-active Ni ultramicroelectrode.
Here, we demonstrate a method of preparing a SERS-active Ni ultramicroelectrode through electrochemical deposition of several atomic layers of …
Sorption Of Ions Of Some Metals On Synthesized Weakly Basic Ion Exchangers, Dilmurod Azimov, S. Turabjanov, Farrukh Igitov, Rano Nazirova, Tulkin Tursunov
Sorption Of Ions Of Some Metals On Synthesized Weakly Basic Ion Exchangers, Dilmurod Azimov, S. Turabjanov, Farrukh Igitov, Rano Nazirova, Tulkin Tursunov
CHEMISTRY AND CHEMICAL ENGINEERING
The purpose of the study is to test a weakly basic anion exchanger of the polycondensation type in the processes of sorption of ions of copper, nickel, cobalt, zinc, cadmium. Among the indicated metal ions, the maximum sorption was established for copper ions.
To study the process of sorption of copper ions by the tested anion exchanger, the method of potentiometric titration was used. It was found that copper ions are sorbed by the anion exchanger in the form of a complex in the range of pH = 3,4-4,2. The formation of the copper ions complexes decreases with an increase …
Fabrication And Characterization Of Highly Ordered Aao Nanotubes, Anvar Khamidov, Farhod Hoshimov, Suvonkul Erkhanovich Nurmonov, Olim Ruzimuradov, Shavkat Mamatkulov
Fabrication And Characterization Of Highly Ordered Aao Nanotubes, Anvar Khamidov, Farhod Hoshimov, Suvonkul Erkhanovich Nurmonov, Olim Ruzimuradov, Shavkat Mamatkulov
CHEMISTRY AND CHEMICAL ENGINEERING
Investigated the electrochemical synthesis and characterized of a nanometer scale porous anodic aluminum oxide (AAO) membranes with a mean pore diameter about of 80-100 nm. The anodizing process done by varying the anodizing temperature from 20 °C to 25 °C. The membranes exhibit interesting properties such as controllable pore diameters, periodicity and density distribution. These properties can preselected by adjusting the controlling parameters of a temperature controlled two-step anodization process. The surface features of the nanometer scale membrane such as pore density, pore diameter and interpore distance were quantified using scanning electron microscopy (SEM) and atomic force microscopy (AFM). SEM …
Improving Accuracy Of Unmanned Aerial System Thermal Infrared Remote Sensing For Use In Energy Balance Models In Agriculture Applications, Mitchell S. Maguire, C.M.U. Neale, Wayne E. Woldt
Improving Accuracy Of Unmanned Aerial System Thermal Infrared Remote Sensing For Use In Energy Balance Models In Agriculture Applications, Mitchell S. Maguire, C.M.U. Neale, Wayne E. Woldt
Department of Mechanical and Materials Engineering: Faculty Publications
Unmanned aerial system (UAS) remote sensing has rapidly expanded in recent years, leading to the development of several multispectral and thermal infrared sensors suitable for UAS integration. Remotely sensed thermal infrared imagery has been used to detect crop water stress and manage irrigation by leveraging the increased thermal signatures of water stressed plants. Thermal infrared cameras suitable for UAS remote sensing are often uncooled microbolometers. This type of thermal camera is subject to inaccuracies not typically present in cooled thermal cameras. In addition, atmospheric interference also may present inaccuracies in measuring surface temperature. In this study, a UAS with integrated …
Durability Of Concrete Using Foundry Waste Sand, Meshari Alrajab
Durability Of Concrete Using Foundry Waste Sand, Meshari Alrajab
Morehead State Theses and Dissertations
A thesis presented to the faculty of the College of Business and Technology Morehead State University in partial fulfillment of the requirements for the Degree Master of Science by Meshari Alrajab on April 20, 2021.
Quantifying Surface Morphology Of Manufactured Activated Carbon And The Waste Coffee Grounds Using The Getis-Ord-Gi* Statistic And Ripley’S K Function, Sanghoon Lee, Sukjoon Na, Olivia G. Rogers, Sungmin Youn
Quantifying Surface Morphology Of Manufactured Activated Carbon And The Waste Coffee Grounds Using The Getis-Ord-Gi* Statistic And Ripley’S K Function, Sanghoon Lee, Sukjoon Na, Olivia G. Rogers, Sungmin Youn
All Engineering Faculty Research
Activated carbon can be manufactured from waste coffee grounds via physical and/or chemical activation processes. However, challenges remain to quantify the differences in surface morphology between manufactured activated carbon granules and the waste coffee grounds. This paper presents a novel quantitative method to determine the quality of the physical and chemical activation processes performed in the presence of intensity inhomogeneity and identify surface characteristics of manufactured activated carbon granules and the waste coffee grounds. The spatial density was calculated by the Getis-Ord-Gi* statistic in scanning electron microscopy images. The spatial characteristics were determined by analyzing Ripley’s K function and complete …
Lecture 00: Opening Remarks: 46th Spring Lecture Series, Tulin Kaman
Lecture 00: Opening Remarks: 46th Spring Lecture Series, Tulin Kaman
Mathematical Sciences Spring Lecture Series
Opening remarks for the 46th Annual Mathematical Sciences Spring Lecture Series at the University of Arkansas, Fayetteville.
Securing Pint Glasses On Serving Trays With Magnetic Attachments, Jayden Commendatore
Securing Pint Glasses On Serving Trays With Magnetic Attachments, Jayden Commendatore
Senior Theses
It is extremely common for servers in the restaurant industry to have pint glasses slip off their serving tray, wasting both time and money for the restaurant. I have designed a sleeve attachment that will clip on to the bottom of a pint glass. The metal sleeve attachment will be attracted to a magnet placed into the serving tray. This increases the normal force of the pint glass, resulting in an increase in the friction force between the tray and sleeve attachment, and helping secure the glass to the tray. In order to optimize the design, the value of the …
Six-Sigma Quality Management Of Additive Manufacturing, Hui Yang, Prahalad Rao, Timothy Simpson, Yan Lu, Paul Witherell, Abdalla R. Nassar, Edward Reutzel, Soundar Kumara
Six-Sigma Quality Management Of Additive Manufacturing, Hui Yang, Prahalad Rao, Timothy Simpson, Yan Lu, Paul Witherell, Abdalla R. Nassar, Edward Reutzel, Soundar Kumara
Department of Mechanical and Materials Engineering: Faculty Publications
Quality is a key determinant in deploying new processes, products, or services and influences the adoption of emerging manufacturing technologies. The advent of additive manufacturing (AM) as a manufacturing process has the potential to revolutionize a host of enterprise-related functions from production to the supply chain. The unprecedented level of design flexibility and expanded functionality offered by AM, coupled with greatly reduced lead times, can potentially pave the way for mass customization. However, widespread application of AM is currently hampered by technical challenges in process repeatability and quality management. The breakthrough effect of six sigma (6S) has been demonstrated in …
Anisotropic Scaffolds For Peripheral Nerve And Spinal Cord Regeneration, Wen Xue, Wen Shi, Yunfan Kong, Mitchell Kuss, Bin Duan
Anisotropic Scaffolds For Peripheral Nerve And Spinal Cord Regeneration, Wen Xue, Wen Shi, Yunfan Kong, Mitchell Kuss, Bin Duan
Department of Mechanical and Materials Engineering: Faculty Publications
The treatment of long-gap (>10 mm) peripheral nerve injury (PNI) and spinal cord injury (SCI) remains a continuous challenge due to limited native tissue regeneration capabilities. The current clinical strategy of using autografts for PNI suffers from a source shortage, while the pharmacological treatment for SCI presents dissatisfactory results. Tissue engineering, as an alternative, is a promising approach for regenerating peripheral nerves and spinal cords. Through providing a beneficial environment, a scaffold is the primary element in tissue engineering. In particular, scaffolds with anisotropic structures resembling the native extracellular matrix (ECM) can effectively guide neural outgrowth and reconnection. In …
Assessing Change In Runoff Water Parameters Through Road Shoulder Vegetated Filter Strips: Experimental Comparison Of Soils And Engineered Infiltration Media, Andrew Corrado, Mohammad Shokri
Assessing Change In Runoff Water Parameters Through Road Shoulder Vegetated Filter Strips: Experimental Comparison Of Soils And Engineered Infiltration Media, Andrew Corrado, Mohammad Shokri
The Pegasus Review: UCF Undergraduate Research Journal
Placement of Vegetated Filter Strips (VFS) along roadways may facilitate removal of nutrients from stormwater runoff. The objective of this research is to compare water quality performance of a VFS containing engineered media to that of typical Florida sandy soil. Storms of variable intensity were simulated over two 1:1 scale physical models of typical one- and two-lane roadway shoulders, one with engineered media (treatment), and one without (control). Simulated roadway runoff was introduced as sheet flow from the roadway and precipitation was applied with a rainfall simulator. Samples of runoff and infiltrate were tested for Dissolved Oxygen (DO) concentration and …
Dynamics Of Running Processes In The Area Of Underless Water Intake, D.R. Bazarov, M.P. Tashkhanova, A. Gayur, M. Sapaeva
Dynamics Of Running Processes In The Area Of Underless Water Intake, D.R. Bazarov, M.P. Tashkhanova, A. Gayur, M. Sapaeva
Irrigation and Melioration
The paper analyzes the dynamics of channel processes based on the results of field studies of the Amudarya River at the site of the damless water intake to the Karshi Magistralny Canal (KMK) and developed recommendations for improving the water intake conditions. Based on the results of field studies of the head section of the inlet channel, an assessment of the state of the Amudarya river bed in the water intake zone was made. The results of studies of the hydraulic and alluvial regimes of the Amu Darya River in the area of the damless water intake are generalized The …
Determination Of The Optimal Hydromodule Of Irrigation Network For Drip Irrigation, R.Zh. Karshiev, A. Urazkeldiev, A.H. Radjabov, A.I. Ernazarov
Determination Of The Optimal Hydromodule Of Irrigation Network For Drip Irrigation, R.Zh. Karshiev, A. Urazkeldiev, A.H. Radjabov, A.I. Ernazarov
Irrigation and Melioration
Most of the irrigation canals operating in the country were built in the 60s and 80s of the XX century, their hydraulic parameters were designed and adapted to the irrigation regimes of agricultural crops, mainly for surface irrigation, and the average hydromodule values were 0,8-1,0 l / s. , the hydraulic parameters of the channel are designed to carry large volumes of water in a short period of time. Over the next 3-4 years, the introduction of water-saving technologies in the irrigation of agricultural crops by farms and "Clusters" requires the improvement of hydraulic methods of irrigation management, the use …
Assessment Of The Impact Of Climate Change On Hydrological Processes In The Chirchik River Basin, Kh.Sh. Gafforov, Sh.D. Sh.D.Tursunboev
Assessment Of The Impact Of Climate Change On Hydrological Processes In The Chirchik River Basin, Kh.Sh. Gafforov, Sh.D. Sh.D.Tursunboev
Irrigation and Melioration
The importance of assessing past and future climate differences plays an important role in future planning in relation to climate change. This situation requires urgent and concerted action in several areas: technology, infrastructure, politics, economics, and the environment. The article evaluates the impact of changes in precipitation intensity on the water level in the global circulation model (GCM) RCP 4.5 and 8.5 scenarios in the 2030s, 2050s, and 2070s. This study is a useful reference for improving water resource management and ensuring the sustainability of agricultural products in the future, as well as for improving operational water management and agricultural …
Assessment Of The Impact Of Climate Change On Hydrological Processes In The Chirchik River Basin, В.K. Saliev
Assessment Of The Impact Of Climate Change On Hydrological Processes In The Chirchik River Basin, В.K. Saliev
Irrigation and Melioration
The article examines the assessment of the state and problems of irrigation water use in the republic in the past and in the near future. A comparative analysis of the state of water resources use for the period of the last 30 years from 1989 to 2019 was carried out.According to the estimates, own water withdrawal for 5 years (2014/15-2018/19) shows that an average of 53.2 m3, including 50.5 billion m3 from rivers At present (2018-2019), an average of 57.06 billion m3 of water is taken for irrigation of 4.289 million hectares of land, against 63.02 billion m3 approved in …
Environmental Damage Caused By Transport Equipment Waste, M. Radkevich, K. Shipilova, M. Abdukodirova, O. Pochugevski
Environmental Damage Caused By Transport Equipment Waste, M. Radkevich, K. Shipilova, M. Abdukodirova, O. Pochugevski
Irrigation and Melioration
The article suggests a new approach to the monetary assessment of the damage caused to the environment by the processed waste of the transport sector. The proposed assessment method is based on the waste collection factor, all types of irretrievable losses and the volume of necessary compensatory release of materials. Based on a survey among vehicle owners, it was found that the solid waste collection rate is about 50 %, while the waste collection rate for operating fluids does not exceed 32 %. In this regard, the bulk of the damage to the environment is caused by liquid waste. Calculations …
Research Of Stress-Deformed State Of Multi-Connected Complex Shell Structures, Т.М. Маvlanov, Sh.O. Khudainazarov, B. Yalgashev, O.S. Nurova
Research Of Stress-Deformed State Of Multi-Connected Complex Shell Structures, Т.М. Маvlanov, Sh.O. Khudainazarov, B. Yalgashev, O.S. Nurova
Irrigation and Melioration
Conducting numerical experiments for complex structurally inhomogeneous structures allows us to understand the qualitative picture of the effect of various parameters in a wide range of studies and to give sound recommendations at the design stage for conducting laboratory model and field experiments. In this paper, on the basis of the classical theory of elasticity, the basic equations characterizing the stress-strain state of complex multiply connected shell structures are given and a specific problem is solved. At the same time, some of the structural elements have viscoelastic properties. When solving the problem, the behavior of the structure for the n-th …
To The Determination Of The Critical Circuit Speed Of The Sharing Drum, Kh. Kh. Igamberdiev, A.B. Mukhitdinov
To The Determination Of The Critical Circuit Speed Of The Sharing Drum, Kh. Kh. Igamberdiev, A.B. Mukhitdinov
Irrigation and Melioration
The article is devoted to the theoretical definition of the critical circumferential speed of the stripping drum of a kena harvester, which depends on the drum diameter, diameter and weight of the stems. It was determined from the equality of the change in the momentum of the stem during impact, i.e. from a shock impulse acting on the stem. The shock impulse is determined when the drum blade touches the stem in the process of stripping, which acts on the mass of the entire stem. The duration of the impact of the drum stripping on the stem was determined from …
An Innovative Seeder For Sowing Non-Loose Seeds Of Saxaul And Cherkez, E.T. Farmonov
An Innovative Seeder For Sowing Non-Loose Seeds Of Saxaul And Cherkez, E.T. Farmonov
Irrigation and Melioration
The main reasons for the absence of a seeder for mechanized sowing of non-loose seeds of fodder plants in deserts are analyzed in the article. The author has developed a technology for sowing non-loose seeds (saxaul and cherkez), which prevents clogging, crushing and breakage in the seeder hopper, and provides for uniform and stable sowing at a set rate and shallow depth over the entire field area without reducing the biological germination. An innovative seeder with a universal sowing unit is recommended. Field tests of the innovative seeder with the proposed universal sowing unit were conducted in February 2020, as …
Recommendations For The Analysis And Safety Assessment Of Turbid Sediments In Flood Reservoirs, А. Yangiev, Sh. Panjiev, D. Adjimuradov
Recommendations For The Analysis And Safety Assessment Of Turbid Sediments In Flood Reservoirs, А. Yangiev, Sh. Panjiev, D. Adjimuradov
Irrigation and Melioration
The article presents the results of field research conducted in Langar, Dehkanabad, Shurabsoy flood reservoirs in the Kashkadarya region.There are many problems as a result of floods in the reservoirs, there are disturbances in the discharge and drainage facilities during the passage of accidental floods.At the same time, there was a large accumulation of turbid-sediments in flood reservoirs.In the article, the results of the calculations using empirical formulas for predicting the amount of turbid sediments in Langar, Dehkanabad, Shurabsoy flood reservoirs up to 2025-2030 years are also presented, and it is noted that at present their useless volumes are full …
Justification Of Parameters Of Replaceable Working Parts Of A Combined Machine, А.A. Akhmetov, L.B. Muratov
Justification Of Parameters Of Replaceable Working Parts Of A Combined Machine, А.A. Akhmetov, L.B. Muratov
Irrigation and Melioration
In article are described the design and options for completing the replaceable working parts of the combined machine for continuous tillage which of the formation of ridges and ridges for sowing re-crops. The parameters of the ridge former and apron-leveler of this machine have been substantiated. The rational values of the parameters of the comb-former are: length 600 mm, width of the entrance edge 680 mm, height of the blade 160 mm, length of the side edge of the blade 178 mm. The rational values of the working length and height of the leveling apron are 220 mm and 200 …
Development Of An Algorithm For Optimization Of Continuous Technological Process Of Cultivation Of Microorganisms, Sh.R. Rakhmanov
Development Of An Algorithm For Optimization Of Continuous Technological Process Of Cultivation Of Microorganisms, Sh.R. Rakhmanov
Irrigation and Melioration
In article the analysis of possible modes of microalgae cultivation has been carried out. Two optimization algorithms are substantiated. The first one is based on the method of random search with an absolute bias, an algorithm for optimizing the process of cultivating microorganisms with continuous regeneration of the flow in one cultivator. The second is an algorithm for determining the optimal residence time of chlorella particles in multistage cultivators, focused on the method of dynamic programming, implemented in Wellman's recurrence relation. The developed algorithm for operational forecasting and automatic control of the chlorella cultivation process allows, under given production conditions …
Covid-19 Impact To Family Food Consumption And Income In Uzbekistan: Results Of An Online Survey, Kh. Pardaev, Sh. Hasanov, S. Mamasoliev, Sh. Muratov, R. Kalandarov, U. Nurullaev
Covid-19 Impact To Family Food Consumption And Income In Uzbekistan: Results Of An Online Survey, Kh. Pardaev, Sh. Hasanov, S. Mamasoliev, Sh. Muratov, R. Kalandarov, U. Nurullaev
Irrigation and Melioration
This article aims to study the impact of the pandemic on food consumption by families in Uzbekistan. The shock of the pandemic is threatening the well-being of families in Uzbekistan, as in all developing countries. The study focuses on the effects of changes in food prices, declining consumption, and changes in household incomes. The Instrumental regression model was used in the factor impact analysis. Data for analysis were collected online by messenger groups from families in urban and rural areas of Uzbekistan. Results of the Econometric analysis demonstrated that the decline in food consumption in households was assessed by a …
Status Of Crop Diversification And Its Empirical Analysis: A Case Study Of The Republic Of Uzbekistan, A.E. Primov
Status Of Crop Diversification And Its Empirical Analysis: A Case Study Of The Republic Of Uzbekistan, A.E. Primov
Irrigation and Melioration
The main objective of this study is to determine the status and level of crop diversification among farms in the country through an empirical analysis using panel data collected in 2009-2017. In doing so, we performed the Stata-16 software using the Simpson Diversification Index model in determining the diversification index. According to the results, the highest diversification indicators were found for Samarkand, Fergana and Tashkent regions, respectively, and accounted for 0.74, 0.74 and 0.76, respectively. It can be seen that the existing farms in Tashkent region used more diversified crops than in other regions of the country. The average diversification …
Efficiency Of Using Graphic Software In The Design Of Hydrotechnical Structures, U.A. Nasritdinova, A.M. Khodjaev, Z.I. Kayumova
Efficiency Of Using Graphic Software In The Design Of Hydrotechnical Structures, U.A. Nasritdinova, A.M. Khodjaev, Z.I. Kayumova
Irrigation and Melioration
The article examines the work of scientists engaged in research in this area in the design of hydrotechnic structures. The possibilities of design programs for the application of the results of scientific research in the educational process were used. Thanks to the design in these programs, practical tasks are carried out with the utmost precision. The use of computer technology in teaching the subject "Hydrotechnical structures" and the use of graphic software AutoCAD in the design of linear platforms for clothing, curved platforms for clothing from hydrotechnical structures are shown in 2D and 3D three-dimensional modeling.
Influence Of Parameters Of Non-Standard Modes Of Heat Treatment On Increasing The Wear Resistance Of Steel Products, Dorob Murotovich Berdiyev Dsn, Abdulaziz Abdullajanovich Yusupov Head Teacher, Ravshan Kobilovich Tashmatov Doctoral Student, Tuychi Nemat Ogli Ibodullayev Assistant, Kabira Erkinovna Qurbonova Head Teacher
Influence Of Parameters Of Non-Standard Modes Of Heat Treatment On Increasing The Wear Resistance Of Steel Products, Dorob Murotovich Berdiyev Dsn, Abdulaziz Abdullajanovich Yusupov Head Teacher, Ravshan Kobilovich Tashmatov Doctoral Student, Tuychi Nemat Ogli Ibodullayev Assistant, Kabira Erkinovna Qurbonova Head Teacher
Scientific-technical journal
The use of non-standard modes of heat treatment increases the density of dislocations in the crystal structure of the α-phase and increases the wear resistance of carbon, low-alloy steels under various friction conditions, which is comparable to the results when heated to a standard temperature (Ac3+30÷50 °C). The preliminary extreme heating temperature is determined. After re-quenching at standard temperature and low tempering, the wear resistance of steels under various types of friction increases by up to 40 % compared to standard quenching.
Influence Of Parameters Of Non-Standard Modes Of Heat Treatment On Increasing The Wear Resistance Of Steel Products, Dorob Murotovich Berdiyev Dsn, Abdulaziz Abdullajanovich Yusupov Head Teacher, Ravshan Kobilovich Tashmatov Doctoral Student, Tuychi Nemat Ogli Ibodullayev Assistant, Kabira Erkinovna Qurbonova Head Teacher
Influence Of Parameters Of Non-Standard Modes Of Heat Treatment On Increasing The Wear Resistance Of Steel Products, Dorob Murotovich Berdiyev Dsn, Abdulaziz Abdullajanovich Yusupov Head Teacher, Ravshan Kobilovich Tashmatov Doctoral Student, Tuychi Nemat Ogli Ibodullayev Assistant, Kabira Erkinovna Qurbonova Head Teacher
Scientific-technical journal
The use of non-standard modes of heat treatment increases the density of dislocations in the crystal structure of the α-phase and increases the wear resistance of carbon, low-alloy steels under various friction conditions, which is comparable to the results when heated to a standard temperature (Ac3+30÷50 °C). The preliminary extreme heating temperature is determined. After re-quenching at standard temperature and low tempering, the wear resistance of steels under various types of friction increases by up to 40 % compared to standard quenching.
Modulation Of Mechanical Stress Mitigates Anti-Dsg3 Antibody-Induced Dissociation Of Cell–Cell Adhesion, Xiaowei Jin, Jordan Rosenbohm, Eunju Kim, Amir Monemian Monemianesfahani, Kristina Seiffert-Sinha, James K. Wahl Iii, Jung Yul Lim, Animesh A. Sinha, Ruiguo Yang
Modulation Of Mechanical Stress Mitigates Anti-Dsg3 Antibody-Induced Dissociation Of Cell–Cell Adhesion, Xiaowei Jin, Jordan Rosenbohm, Eunju Kim, Amir Monemian Monemianesfahani, Kristina Seiffert-Sinha, James K. Wahl Iii, Jung Yul Lim, Animesh A. Sinha, Ruiguo Yang
Department of Mechanical and Materials Engineering: Faculty Publications
It is becoming increasingly clear that mechanical stress in adhesive junctions plays a significant role in dictating the fate of cell–cell attachment under physiological conditions. Targeted disruption of cell–cell junctions leads to multiple pathological conditions, among them the life-threatening autoimmune blistering disease pemphigus vulgaris (PV). The dissociation of cell–cell junctions by autoantibodies is the hallmark of PV, however, the detailed mechanisms that result in tissue destruction remain unclear. Thus far, research and therapy in PV have focused primarily on immune mechanisms upstream of autoantibody binding, while the biophysical aspects of the cell– cell dissociation process leading to acantholysis are less …
Modulation Of Mechanical Stress Mitigates Anti-Dsg3 Antibody-Induced Dissociation Of Cell–Cell Adhesion, Xiaowei Jin, Jordan Rosenbohm, Eunju Kim, Amir Monemian Esfahani, Kristina Seiffert-Sinha, James K. Wahl Iii, Jung Yul Lim, Animesh A. Sinha, Ruiguo Yang
Modulation Of Mechanical Stress Mitigates Anti-Dsg3 Antibody-Induced Dissociation Of Cell–Cell Adhesion, Xiaowei Jin, Jordan Rosenbohm, Eunju Kim, Amir Monemian Esfahani, Kristina Seiffert-Sinha, James K. Wahl Iii, Jung Yul Lim, Animesh A. Sinha, Ruiguo Yang
Department of Mechanical and Materials Engineering: Faculty Publications
It is becoming increasingly clear that mechanical stress in adhesive junctions plays a significant role in dictating the fate of cell–cell attachment under physiological conditions. Targeted disruption of cell–cell junctions leads to multiple pathological conditions, among them the life-threatening autoimmune blistering disease pemphigus vulgaris (PV). The dissociation of cell–cell junctions by autoantibodies is the hallmark of PV, however, the detailed mechanisms that result in tissue destruction remain unclear. Thus far, research and therapy in PV have focused primarily on immune mechanisms upstream of autoantibody binding, while the biophysical aspects of the cell– cell dissociation process leading to acantholysis are less …
Solid-State Transducer, System, And Method, Andrew Barnard
Solid-State Transducer, System, And Method, Andrew Barnard
Michigan Tech Patents
The present disclosure includes solid-state transducers, a system, and a method. In one embodiment, a solid-state transducer includes a housing, a first end portion, a second end portion, a plurality of electrical conductors, and a thin-film resistive material. The thin-film resistive material is disposed between and in electrical communication with a plurality of electrical conductors. The thin-film resistive material is configured to receive one or more electrical signals from the plurality of electrical conductors, and generate thermal oscillations to create pressure waves in a medium in response to receiving the one or more electrical signals.