Digital Commons Network^™

Early Life Exposure To Antibiotics Increases The Risk Of Myopia: A Retrospective Cohort Study, Peng-Tai Tien, Chang-Ching Wei, Sheng-Chun Lin, Ping Ping Meng, Yu-Te Huang, Jamie Jiin-Yi Chen, Ming-Yen Wu, Ying-Hsiu Shih, Tzu-Ju Hsu, Fuu-Jen Tsai, Yao-Chien Wang, Hui-Ju Lin, Lei Wan

BioMedicine

Background

Myopia is a growing health issue, expected to affect nearly half of the global population by 2050. Genetic predisposition and early environmental influences both play crucial roles in the development of myopia. Identifying modifiable risks and early interventions is critical. Antibiotics, commonly given to young children, may disrupt gut microbiota, which has been linked to ocular diseases in humans and animals.

Aim We aimed to investigate the association between antibiotic use in early life and the risk of developing myopia.

Methods Retrospective cohort study using data from a national health insurance database examined children aged three years or younger, …

Extending Sbar To Sbar-A: A Practice-Based Framework For Dnp Clinical Scholarship, Cynthia Plonien

Nursing Faculty Publications & Presentations

The SBAR (Situation, Background, Assessment, Recommendation) framework is widely used to structure communication in healthcare settings. However, its traditional use emphasizes information exchange rather than practice change. Doctor of Nursing Practice (DNP) education requires translation of evidence into action through measurable practice change and leadership engagement. This manuscript introduces SBAR-A, an adaptation of the SBAR framework that adds an “Action” component requiring application of evidence-based interventions. SBAR-A integrates planning, leadership, and the application of knowledge to practice. This framework provides a structured approach for bridging communication and practice change within DNP clinical scholarship.

The Correlation Between Perceptual Abilities And The Acquisition Of Non-Native Consonant Clusters, Hope Emma Nielson

Theses and Dissertations

A common approach in the study of speech motor learning is to have speakers learn to produce clusters of consonants that do not occur in their native language. This study investigated the relationship between auditory or speech perceptual abilities and the initial acquisition of non-native stop-stop consonant clusters. Sixty young adult participants (56 female, four male) were administered a gap detection test and a speech-in-noise test to assess their innate perceptual skills. The participants then performed a nonsense-word repetition task featuring non-native consonant clusters in the initial position. The participants' spoken productions of the nonwords were recorded and analyzed acoustically …

Expert Recommendations To Strengthen Chikungunya Outbreak Surveillance And Reporting For Traveler Health Protection, Daniel C. Payne, Karoun H. Bagamian, Jeffery Goad, Nathan D. Grubaugh, Michael A. Johansson, Moritz U. G. Kraemer, Eyal Leshem, Francesca F. Norman, Alfonso J. Rodríguez-Morales, Henrik Salje, Stephen Thomas, Scott C. Weaver, Lindsey A. Laytner, Rebecca Sturgis, Suzanne K. Scheele, Davidson H. Hamer

Pharmacy Faculty Articles and Research

Chikungunya, a debilitating mosquito-borne disease caused by chikungunya virus, has surged dramatically in the past two decades. Chikungunya outbreaks can intensify rapidly, with infections posing a significant endemic health burden in tropical/subtropical areas and for travelers. Health professionals require timely and accurate outbreak information to adequately protect travelers and assess chikungunya risk. However, detection is often insufficient in the areas most susceptible to outbreaks, leading to diagnostic and reporting delays. Consequently, travelers are often unaware of increased chikungunya infection risk at their destination. We assessed chikungunya surveillance and reporting resources, and we developed expert recommendations for traveler health protection. Because …

Behind The Bar: Empathy Burnout's Impact On Lawyers' Job Competency, Eva L. Newkirk

Honors Projects

It is well established within psychological literature how burnout develops among human service professionals including nurses, therapists, police officers, and first responders. Despite facing the same kinds of risks for burnout development by helping professions, especially trauma and stressful client relationships, the development and consequences empathy burnout have been under-researched in lawyers. This project aims to explore existing literature around burnout and empathy as related to job competency in legal professionals and develop a survey that explores empathy as a potential indirect mediating variable from burnout to employee engagement. The article additionally discusses the pathway from second-hand trauma to empathy …

Weekly Published Magazine Covers During World War Ii: Cover Photos Used To Represent The Wartime Experience, Annika B. Larson

Theses and Dissertations

Weekly published magazines served largely as news outlets during World War II, and the images on the covers of these magazines were not only an attention catcher and tone setter, but were images chosen to represent the ever-changing landscape both on the homefront and internationally. In addition, these publications often used photographs that represented the developments their allies and enemies were making in tandem with domestic coverage. The entities publishing the magazines were managed by both the government and independent civilians, dependent on the country, thus providing different views of the war. The coverage in the United States and United …

Summer School As A Second Chance For Success For Children: Perceptions Of Stakeholders In A Middle Level Summer School Intervention Program- A Mixed-Methods Study, Sara M. Smith

Electronic Theses and Dissertations

In the American education system, there is a responsibility of the system to educate all children. Research reveals that there are conflicting ideas on how to address students who are not on track to successfully complete K-12 schooling. Oftentimes, retention policies are utilized in schools to address these students. However, there is a great amount of research that reveals that retention policies have negative effects on a student’s educational trajectory in K-12 schooling. Vulnerable subgroups of students, such as students in poverty and other diverse learners, are even more affected by these policies.

This study focused on the current research …

Molecular Classification And Association With Survival Outcomes In High-Intermediate And High-Risk Early-Stage Endometrial Cancers: Ancillary Analysis Of Gog-0249, Lindsay Kuroki, Danielle Enserro, Heather Lankes, Kyle Strickland, Rebecca Previs, Aine Clements, Matthew Powell, Ann Klopp, Elena Ratner, Paul Disilvestro, Casey Cosgrove, Guilherme Henrique Cantuaria, Nicola Spirtos, Michael Carney, Mitchell Edelson, Gottfried Konecny, Penny Anderson, Christopher Tarney, Britt Erickson, Meredith Newton, Krishnansu Tewari, Premal Thaker, David Warshal, Amy Armstrong, Xun Clare Zhou, Angeles Alvarez Secord

Abington Jefferson Health Papers

OBJECTIVE: Determine whether mismatch repair (MMR) and p53 expression predict recurrence-free survival (RFS) and overall survival (OS) in early-stage endometrial cancer (EC) patients treated with vaginal cuff brachytherapy plus chemotherapy (VCB/C) versus pelvic radiation therapy (RT).

METHODS: In the GOG-0249 trial, 601 patients with high-intermediate risk (HIR) early-stage EC were randomized to VCB/C (carboplatin/paclitaxel for 3 cycles) or pelvic RT. Molecular subgroups, deficient MMR (dMMR), p53 wildtype (p53wt), p53 abnormal (p53abn), were determined by immunohistochemistry. Five-year RFS and OS were analyzed using Kaplan-Meier curves and Cox proportional hazards models, adjusting for lymphadenectomy, planned VCB, and treatment group.

RESULTS: Among 315 …

Modulate Obesity And Related Metabolic Complications For Yielding Improvements In Ibd Outcomes (Modify-Ibd): Consensus On Obesity And Cardiometabolic Comorbidities In Inflammatory Bowel Disease Using Systematic Reviews And The Rand/Ucla Appropriateness Method, Jalpa Devi, Sami Samaan, Priya Sehgal, Mouhand Mohamed, Matthew Vincent, Shannon Coombs, Michelle Doering, Edward L. Barnes, Amanda M. Johnson, Andres J. Yarur, Parakkal Deepak

Division of Gastroenterology and Hepatology Faculty Papers

INTRODUCTION: Obesity and related cardiometabolic comorbidities, including hypertension, dyslipidaemia, diabetes, metabolic dysfunction-associated steatotic liver disease and atherosclerotic cardiovascular disease, are increasingly prevalent among individuals with inflammatory bowel disease (IBD). These conditions influence disease activity, therapeutic response, surgical outcomes and overall quality of life, yet evidence remains fragmented. The Modulate Obesity and relateD metabolic complIcations For Yielding improvements in IBD outcomes (MODIFY-IBD) initiative aims to synthesise evidence and generate consensus recommendations to guide practice and future research in this area. This study describes a protocol for a structured evidence synthesis and Research And Development/University of California, Los …

Review Of William Aylward, Jacques Des Courtils, Bonna D. Wescoat (Eds.). 2025. Architectural Networks In The North Aegean: Thasos, Samothrace, And The Formation Of Hellenistic Design. Madison, Wi: University Of Wisconsin Press. Pp. Xi, 307. Hardcover. (Isbn 9780299350109) $119.95., Asja Müller

New England Classical Journal

No abstract provided.

Review Of Paul Roche (Ed.). 2021. Reading Lucan’S Civil War: A Critical Guide. Oklahoma Series In Classical Culture Vol. 62. Norman: University Of Oklahoma Press. Pp. Viii, 338. Paperback. (Isbn 978-0-8061-6939-2). $34.95., Timothy Joseph

New England Classical Journal

No abstract provided.

Pol 51: Intro To Political Theory Syllabus, Jamie Aroosi

Open Educational Resources

This is a syllabus for Intro to Political Theory following revisions in an OER refresher course

United States V. Jackson: Clarifying The Scope Of The Off-Label Use Privilege As Applied To The Reuse Of Single-Use Medical Devices, Marissa Lawson

Maryland Law Review Online

No abstract provided.

The Constitutional Dimension Of Ai: A Phenomenology Of Cybernetic Power, Andrea Simoncini

Maryland Law Review Online

No abstract provided.

Ai-Infused Writing-Intensive Problems For Introduction To Programming In C++, Esma Yildirim

Open Educational Resources

This exercise book uses Writing-Intensive (WI) pedagogy in an introductory programming course setting, because I believe WI can help students engage in deeper analysis of programming problems while strengthening their critical and analytical thinking skills. In computer science, a single problem can often be solved using multiple algorithms, designs, and implementation strategies. Exploratory thinking and reflective writing can improve students’ ability not only to read and write computer programs, but also to evaluate the efficiency, readability, and maintainability of algorithms and code. Students must learn not only how to design solutions, but also how to compare alternatives and determine the …

Mother Knows Best? Mahmoud V. Mcknight And The Question Of Parental Free Speech In Public School Curriculum Selection, Natalie Wren

Maryland Law Review Online

No abstract provided.

Rethinking Functional Groupings In Basketball Wings Through Ecological Trait Frameworks, Dhruv Mehrotra

Theses and Dissertations

This paper starts with a review about Plant Functional Types and then goes deeper into the conceptual foundations of Plant Functional Types (PFT's) with detailed discussion of global trait spectra such as the leaf economics spectrum and the fast-slow continuum. Using concepts like response and effect traits, the review then talks about how a trait based ecological framework can provide a more robust guideline to classify plants. The review then talks about how players in basketball have been classified in the past along with some of the newer typologies. The review starts to draw some parallels between the ecological framework …

Acidic Extracellular Ph-Induced Pth Secretion In Male Mouse Parathyroids Is Ogr1-Dependent, Yanmei Yang, Mengcun Chen, Mingshu Cui, Elisabeth Lashbrooks, Bin Wang

Center for Translational Medicine Faculty Papers

The role of extracellular acidity in regulating PTH secretion in cultured mouse parathyroid glands (PTGs) has not been studied to date, largely because of the technical difficulty of isolating mouse PTGs. We hypothesized that acidic extracellular pH directly stimulates PTH secretion through activation of a proton-sensing receptor, specifically ovarian cancer G protein-coupled receptor 1 (OGR1, also known as GPR68). To test this, we developed a method to reliably identify and isolate PTGs from male mice by administering 5-aminolevulinic acid, which induced selective fluorescence in these glands. Using this model, we demonstrate that acidic extracellular pH significantly stimulates PTH secretion in …

Effect Of Variable Rpms And Vertical Offset On Deposited Dot Diameter And Mass In A Lens Machine, Max A. Siefert

Mechanical Engineering and Materials Science Independent Study

The Laser Net Engineered Shaping (LENS) machine uses a Direct Layer Deposition (DLD) additive manufacturing method to create metallic alloy components and libraries in the Flores Lab. This DLD process uses nozzles to blow metallic powders into a melt pool created by a laser. Much of this powder gets wasted due to the small diameter of the melt pool and large area of the powder blown. By changing several processing variables, in this case the nozzle distance from the laser focus (Z-offset) and mass flow rate of the powder (RPMS). It was found a larger dot diameter correlated with an …

Internalized Homophobia As An Influence On Participation In Hiv Prevention Among Young Men Who Have Sex With Men (Ymsm), Kasey I. Brazee

Honors Scholar Theses

Stigma is a known barrier to accessing preventative services for human immunodeficiency virus (HIV), however, the types of stigmas involved in this relationship remain not well defined. Homophobia, or negative attitudes directed towards homosexuality, is a particularly important type of stigma considering the disproportionate effect of HIV on men who have sex with men (MSM). Young MSM (YMSM) are especially impacted, making them a key population in the context of HIV prevention research.  Internalized homophobia, which refers to homophobia that one directs towards themselves, is under researched regarding its role in participating in HIV prevention. In this study, we aimed …

Acidic Extracellular Ph-Induced Pth Secretion In Male Mouse Parathyroids Is Ogr1-Dependent, Yanmei Yang, Mengcun Chen, Mingshu Cui, Elisabeth Lashbrooks, Bin Wang

Center for Translational Medicine Faculty Papers

The role of extracellular acidity in regulating PTH secretion in cultured mouse parathyroid glands (PTGs) has not been studied to date, largely because of the technical difficulty of isolating mouse PTGs. We hypothesized that acidic extracellular pH directly stimulates PTH secretion through activation of a proton-sensing receptor, specifically ovarian cancer G protein-coupled receptor 1 (OGR1, also known as GPR68). To test this, we developed a method to reliably identify and isolate PTGs from male mice by administering 5-aminolevulinic acid, which induced selective fluorescence in these glands. Using this model, we demonstrate that acidic extracellular pH significantly stimulates PTH secretion in …

As-1014-26 Resolution On Ufpp 12.2 Number Of Office Hours, Academic Senate Faculty Affairs Committee

Academic Senate Resolutions

Resolves that UFPP 12.2 be revised effective Fall 2026 according to the attached documents; and further resolves that colleges and departments update their office hours policies to conform with the revisions to UFPP 12.2; and be it further that, when published on the Academic Programs and Planning website, the scaling of the office hours to instructional workload shall be translated into both minutes and credit hours; and further resolves that Cal Poly prioritize the development of a directory of faculty office hours accessible within the portal.

A Novel Ffueat Technique Enhancing The Performance Of Multiple Url Classification And Cybersecurity Using Rnn And Transformer-Based Models, Zafar Ali, Siti Sophiayati Yuhaniz, Noureen Noureen, Ghulam Mujtaba, Husham M. Ahmed

Baghdad Science Journal

Thousands of new websites are published every day, which pose significant challenges for web classification and cybersecurity. URL classification datasets, including general and cybersecurity-specific ones, face challenges such as class imbalance, noise, and ambiguous data, which can significantly affect model performance. This study proposes a novel Fine-Tuned FastText Unsupervised Embedding Augmentation Technique (FFUEAT). Datasets (DMOZ and Phishing) were used to evaluate the performance of the proposed technique, achieving F1-scores of 0.8639 with DistilBERT and 0.8891 with BERT. The performance of sparse minority classes, achieving accuracy increases of 20.88% for 'home', 58.04% for 'news', and 11.18% for the 'kids' categories of …

Persistent Health Inequalities Over 20 Years Among Adults With Intellectual Disabilities Who Display Behaviours That Challenge: Evidence From English Primary Care Records, Memta Jagtiani, Aws Sadik, Louise Marston, Shoumitro Deb, Dheeraj Rai, Bhathika Perera, Rohit Shankar, Juliette A. O’Connell, Angela Hassiotis

Peninsula Medical School

BackgroundAdults with intellectual disabilities who display behaviours that challenge (BtC) are more prone to poor health.AimsThis study seeks to evidence the long-term health outcomes for those who display BtC.MethodWe conducted a longitudinal cohort study of adults with intellectual disabilities aged ≥18 years in England, using data from the Clinical Practice Research Datalink Aurum (January 2003 to December 2023) linked to Hospital Episode Statistics and Office for National Statistics. Main outcome measures were annual health checks, general practitioner referrals, emergency visits, out-patient attendance, in-patient admissions and mortality.ResultsAmong 83 166 adults with intellectual disabilities (mean age 38.6 years), 18.5% had a record …

Origin And Age Of Fluvioglacial Sediments On Staten Island Ny And Implications For Meltwater Flow, Jane L. Alexander, Victoria Rivelli, Sean T. Thatcher

Publications and Research

In the northeastern United States, sediments related to the expansion and contraction of the Laurentide ice sheet have been extensively mapped throughout New England, as well as in New Jersey and on Long Island. However, linking these deposits around New York City is challenging due to the extensive urbanization. Staten Island is less developed than the other boroughs of New York City, however outcrops of rock and surface sediment are limited, making interpretation of its geologic history challenging. When small areas of sediment are temporarily exposed, they can be used to improve our understanding of sediment erosion and deposition over …

Cardiac Resynchronization Therapy: A Review, Caique M Ternes, Jitae A Kim, Anirban Basu, Kenneth A Ellenbogen, Mihail G Chelu

Faculty, Staff and Students Publications

Importance: Heart failure (HF) affects more than 64 million individuals worldwide, and acute HF is associated with 1-year mortality rates of 23.6% in North America and Europe. Cardiac dyssynchrony from conduction system disease may cause HF progression, particularly in patients with left ventricular (LV) systolic dysfunction.

Observations: Electrical dyssynchrony in HF most commonly presents as left bundle-branch block and affects 20% to 30% of patients with reduced LV ejection fraction (LVEF). Cardiac resynchronization therapy, which includes biventricular pacing and conduction system pacing, restores synchronous ventricular contraction and is recommended for patients with symptomatic HF despite optimal medical therapy, LVEF of …

Migrainous Thoracalgia In A Patient With Chronic Migraine And Coronary Vasospasm: A Case Report, Dean Zeldich, Victor S. Wang, Cyril David, Clinton Lauritsen, Claire E.J. Ceriani

Department of Neurology Faculty Papers

Migrainous thoracalgia (MT) refers to chest pain (CP) potentially arising from a neurologic etiology, often temporally linked to migraine. We present a 57-year-old woman with chronic migraine who developed recurrent CP typically following migraine attacks. Despite multiple cardiac evaluations, including cardiac MRI and catheterizations, she was diagnosed with fibromuscular dysplasia, spontaneous coronary artery dissection, and coronary microvascular disease. Her CP partially responded to nitroglycerin and improved modestly with migraine control using ubrogepant and calcium channel blockers. During admission for refractory migraine, she received intravenous lidocaine, magnesium, ketorolac, and neuroleptics, resulting in several months of CP remission despite brief migraine relief. …

Hope And The Handiwork Of Varda: Celestial Signposts Of The Music’S Mending, Kristine Larsen

Journal of Tolkien Research

Varda, the Queen of the Valar, wields tremendous cosmological power in Tolkien’s legendarium. It is not without cause that Melkor fears her, as her power is literally written in the stars for all to see. Not only do her bright stars and constellations provide light against the darkness, but two of her creations – the Valacirca (Big Dipper) and Menelmacar (Orion) – are direct and intentional warning signs to Melkor of his unavoidable defeat in the Last Battle at the end of days. Indeed, Melkor’s capture by the armies of the Valar at the end of the First Age is …

Edge Artificial Intelligence (Ai) Guardian: Ai-Powered Predictive And Self-Healing For Bidirectional Forwarding Detection (Bfd) And Internet Protocol Security (Ipsec) Tunnels In Software-Defined Wide Area Network (Sd-Wan), Krushnarajendra H R

Defensive Publications Series

Current Software-Defined Wide Area Network (SD-WAN) solutions are reactive and centralized, lacking the ability to predict and autonomously heal tunnel degradations before outages occur.  To address these limitations, the techniques presented herein implement Edge AI Guardian, a system configured to deploy a lightweight on-device Artificial Intelligence (AI) agent on edge routers to predict tunnel failures in real time, autonomously perform local self-healing actions, and generate natural-language Generative Artificial Intelligence (GenAI)-based root cause summaries without requiring centralized network management connectivity.

The Impact Of Climate Change On Glass Facades: A Bibliometric Analysis, Pelin Akın, Güneş Mutlu Avinç

HBRC Journal

Climate change has direct impacts on the design and performance of building envelopes, necessitating new approaches in the discipline of architecture. In this study, a bibliometric analysis was conducted to understand the effects of climate change on glass façade systems. The 612 academic publications obtained from the Web of Science database were analyzed through R Studio Biblioshiny. Within the scope of the study, publication trends, key themes, prominent authors, institutions and geographical distributions were evaluated in detail. According to the findings of the research, it was indicated that research has gained momentum especially after 2016, focusing on themes such as …