Digital Commons Network^™

Modeling Of Benzimidazole Derivatives As Antimalarial Agents Using Qsar Analysis, Ruslin Hadanu, Marham Sitorus

Makara Journal of Science

In this study, quantitative structure–activity relationship (QSAR) analysis was conducted on 20 homologous compounds of benzimidazole derivatives. The structures of the benzimidazole derivatives were optimized using the semiempirical Parameterized Model 3 method of HyperChem for Windows 8.0 to obtain 14 descriptors. Then, multiple linear regression (MLR) analysis was performed using the backward method. The results of the MLR analysis obtained four new QSAR equation models. Based on statistical criteria, model 1 was determined as the best QSAR equation model in predicting the theoretical IC₅₀ values of the new benzimidazole derivatives. As many as 20 new compounds of benzimidazole derivatives …

Flexible Operation Of Nuclear Hybrid Energy Systems For Load Following And Water Desalination, An Ho, Blake W. Billings, John Hedengren, Kody M. Powell

Faculty Publications

Nuclear hybrid energy systems (NHES) have the potential to provide dependable and emission-free electricity to the grid while also increasing the flexibility and reliability of the electrical grid. Molten salt reactor (MSR) technology can provide consistent, carbon-free electricity while also increasing efficiency, security, and sustainability and reducing nuclear waste. This study investigates the integration of Molten Salt Reactors (MSR) and conventional Pressurized Water Reactors (PWR) with desalination technologies: Direct Contact Membrane Distillation (DCMD), Multi-Stage Flash Distillation (MSFD), and Reverse Osmosis (RO). Dynamic first-principles models were developed and tested using real grid data from the New York Independent System Operator. The …

Nutrition Management In Children Less Than 5 Years Of Age With Glycogen Storage Disease Type I: Survey Results, Mary Sowa, Monica Boyer, Jessica Green, Surekha Pendyal, Heather Saavedra

Faculty, Staff and Student Publications

Background: Nutrition management for GSD Type I (GSDI; OMIM #232200, 232220) is complex, with the goal being to maintain euglycemia while minimizing metabolic derangements. Management guidelines were published in 2002 and 2014. However, there is limited information on the nuances of nutrition management and the unique feeding challenges of children.

Methods: A REDCap survey focusing on staffing and current practices in the nutrition management of children with GSD I who were < 5 years of age was sent to the metabolic dietitian's listserv and GMDI membership in 8/2023.

Results: There were 21 North American respondents. In 17/21 clinics (81%), Prosobee® was the primary choice for infant formula. Dietitians used different methods to determine hourly glucose needs. Fasting …

Management Of Jellyfish Outbreaks To Achieve Good Environmental Status, Yolanda Sagarminaga, Stefano Pirano, Christopher P. Lynam, Valentina Leoni, Athanasios Nikolaou, Cornelia Jaspers, Mar Bosch-Belmar, Lara M. Fumarola, Angel Borja, Emanuela Spada, Eva Amorim, Patrizia Borrello, Roberta De Angelis, Antonella Leone, Natalia Montero, Luis Ferrer, Matthew Holland, Thomas K. Doyle, George Tsirtsis, Stelios Katsanevakis

School of Biological and Marine Sciences

Jellyfish and gelatinous zooplankton (GZ) in general, fulfill important ecological roles with significant impacts, although they are often oversimplified or misunderstood. This paper reviews the impacts, pressures, monitoring methods and current management strategies for various GZ groups. It also introduces potentially applicable indicators for their assessment in ecosystem-based management approaches, such as the European Marine Strategy Framework Directive (MSFD). This multi-faceted review is primarily envisioned to serve as a state-of-the-art document for scientists and policymakers to foster a holistic assessment and management of GZ across European regional seas. The systematic review on global impacts of GZ shows a notable increase …

Spectrum, Volume 53, Issue 3, Sacred Heart University

Newspapers (Obelisk & Spectrum)

Highlights include: SHU Students Hack the Constitution in Annual Event - Big Red Wants You to Vote - 63’s Gets Summer Makeover, -Matt Oestreicher: The Maestro of the Community Theatre, - Intramural Sports Open for Registration

Winonan, Winona State University

The Winonan - 2020s

This issue of the Winonan, the Winona State University student newspaper, was published on September 25, 2024.

Chatgpt Provides Acceptable Responses To Patient Questions Regarding Common Shoulder Pathology, Umar Ghilzai, Benjamin Fiedler, Abdullah Ghali, Aaron Singh, Benjamin Cass, Allan Young, Adil Shahzad Ahmed

Faculty, Staff and Students Publications

BACKGROUND: ChatGPT is rapidly becoming a source of medical knowledge for patients. This study aims to assess the completeness and accuracy of ChatGPT's answers to the most frequently asked patients' questions about shoulder pathology.

METHODS: ChatGPT (version 3.5) was queried to produce the five most common shoulder pathologies: biceps tendonitis, rotator cuff tears, shoulder arthritis, shoulder dislocation and adhesive capsulitis. Subsequently, it generated the five most common patient questions regarding these pathologies and was queried to respond. Responses were evaluated by three shoulder and elbow fellowship-trained orthopedic surgeons with a mean of 9 years of independent practice, on Likert scales …

Dense And Persistent Odor Representations In The Olfactory Bulb Of Awake Mice, Delaram Pirhayati, Cameron L Smith, Ryan Kroeger, Saket Navlakha, Paul Pfaffinger, Jacob Reimer, Benjamin R Arenkiel, Ankit Patel, Elizabeth H Moss

Children’s Nutrition Research Center Staff Publications

Recording and analysis of neural activity are often biased toward detecting sparse subsets of highly active neurons, masking important signals carried in low-magnitude and variable responses. To investigate the contribution of seemingly noisy activity to odor encoding, we used mesoscale calcium imaging from mice of both sexes to record odor responses from the dorsal surface of bilateral olfactory bulbs (OBs). The outer layer of the mouse OB is comprised of dendrites organized into discrete "glomeruli," which are defined by odor receptor-specific sensory neuron input. We extracted activity from a large population of glomeruli and used logistic regression to classify odors …

Skin In The Game: A Review Of Single-Cell And Spatial Transcriptomics In Dermatological Research, Samuel Schepps, Jonathan Xu, Henry Yang, Jenna Mandel, Jaanvi Mehta, Julianna Tolotta, Nicole Baker, Volkan Tekmen, Neda Nikbakht, Paolo Fortina, Ignacia Fuentes, Bonnie Lafleur, Raymond J Cho, Andrew P South

Staff and Researcher Publications

Single-cell RNA sequencing (scRNA-seq) and spatial transcriptomics (ST) are two emerging research technologies that uniquely characterize gene expression microenvironments on a cellular or subcellular level. The skin, a clinically accessible tissue composed of diverse, essential cell populations, serves as an ideal target for these high-resolution investigative approaches. Using these tools, researchers are assembling a compendium of data and discoveries in healthy skin as well as a range of dermatologic pathophysiologies, including atopic dermatitis, psoriasis, and cutaneous malignancies. The ongoing advancement of single-cell approaches, coupled with anticipated decreases in cost with increased adoption, will reshape dermatologic research, profoundly influencing disease characterization, …

Deep Dive Into Pakistan's Ocean Economy: An Evaluation Of Performance And Constraints, Maaziya Aijaz, Omme Hany, Nooreen Mujahid, Ali Abbas

Journal of Ocean and Coastal Economics

Pakistan, a coastal country with a 1,050 km coastline and an Exclusive Economic Zone, relies on the ocean economy for approximately 0.4% of its national GDP. The ocean economy of Pakistan comprises various sectors, including fisheries, maritime transportation, offshore oil and gas exploration, tourism, and marine biotechnology. Over the years, Pakistan has made progress in these sectors, with notable growth in fish exports and the development of deep-sea ports. However, several challenges are hindering the full realization of the ocean's economic potential. These challenges include inadequate infrastructure, outdated regulations, unsustainable fishing practices, pollution, and geopolitical tensions affecting maritime trade. Despite …

Effect Of Reverse Engineering Pedagogy On Students’ Learning Performance, Cultural Heritage Literacy, And Creativity In A Paper Sculpture C-Steam Course, Zehui Zhan, Kai Tu, Huyi Yang, Siping Gao, Xuanxuan Zou

Journal of Educational Technology Development and Exchange (JETDE)

The traditional cultures around the world not only symbolize the spirit and soul of different countries, but also provide the most essential resources for education. This study examined the effect of reverse engineering pedagogy (REP) and forward project pedagogy (FPP) on students’ cultural heritage literacy and creativity in a cultural-oriented STEAM course (C-STEAM). A total of 128 undergraduate students from a major university in China participated in a paper sculpture C-STEAM project, and were randomly divided into two groups: the treatment group (with 64 students) which adopted REP, and the control group (with 64 students) which adopted FPP. Results indicated …

Public Policy And The Future Of Ethnic Studies, Bryce Akira Nishikawa

Silicon Valley Sociological Review

Ethnic Studies (ES) was established in 1968 as part of the Third World Liberation Front’s (TWLF) efforts to reform higher education in ways that incorporated non-euro-centric teaching and increased the racial/ethnic diversity of students and faculty. On many college campuses, ES programs have created spaces for cross-cultural learning that promote respect and champion interpersonal interactions. Over the last 50 years, however, efforts to sustain diversity-centric education have remained isolated attempts by individual colleges and universities. In 2020, this changed when California Governor Gavin Newsom signed into law Assembly Bill 1460. The bill took effect in the 2021-2022 academic year and …

Silicon Valley Sociological Review Vol. 22 2024

Silicon Valley Sociological Review

No abstract provided.

Grossman Gyorgy (Rescued By Vera Parocai) - Holocaust Rescuers Interviews, Sam And Pearl Oliner

Holocaust Rescuers Interviews

No abstract provided.

Proposal For Artist Joe Ruiz Grandee To Serve As The First "Official State Artist Laureate" For The State Of Texas, Kaye Barrett Droke

Don Kennard Papers

Letter sent from Kaye Barrett Droke to Texas Senator Don Kennard on January 7, 1971 regarding a proposal for artist Joe Ruiz Grandee to serve as the first "Official State Artist Laureate" for the State of Texas.

Appointment Of Joe Ruiz Grandee As The First Texas State Artist, Don Kennard

Don Kennard Papers

Memorandum sent to members of the U.S. Senate from Texas Senator Don Kennard on May 28, 1971 regarding appointment of Joe Ruiz Grandee as the first Texas State Artist for the year beginning May 1, 1971 to April 30, 1972.

Impact Conscious Capitalism Flyer, Bryant University

Resources

Flyer for two speakers about conscious capitalism.

Cambridge Ninety Six Historical Record, Cambridge United Methodist Church, Ninety Six

Methodist Local Church Records

No abstract provided.

Cambridge Ninety Six Property Records, Cambridge United Methodist Church, Ninety Six

Methodist Local Church Records

No abstract provided.

Cambridge Ninety Six Membership Records, Cambridge United Methodist Church, Ninety Six

Methodist Local Church Records

No abstract provided.

Central Marion Brittons Neck Membership Records, Central Marion United Methodist Church, Britton's Neck

Methodist Local Church Records

No abstract provided.

Central Marion Brittons Neck Property Records, Central Marion United Methodist Church, Britton's Neck

Methodist Local Church Records

No abstract provided.

Duncan Chapel Harleyville Church History 2005, Duncan Chapel United Methodist Church, Harleyville

Methodist Local Church Records

No abstract provided.

Duncan Chapel Harleyville Membership Records, Duncan Chapel United Methodist Church, Harleyville

Methodist Local Church Records

No abstract provided.

Duncan Chapel Harleyville Pastors Reports 2022-23, Duncan Chapel United Methodist Church, Harleyville

Methodist Local Church Records

No abstract provided.

Duncan Chapel Harleyville Property Records, Duncan Chapel United Methodist Church, Harleyville

Methodist Local Church Records

No abstract provided.

Ebenezer Bowman Church Council Minutes 2023, Ebenezer United Methodist Church, Bowman

Methodist Local Church Records

No abstract provided.

Ebenezer Bowman Church History, Ebenezer United Methodist Church, Bowman

Methodist Local Church Records

No abstract provided.

Ebenezer Bowman Membership Records, Ebenezer United Methodist Church, Bowman

Methodist Local Church Records

No abstract provided.

Ebenezer Bowman Property Records, Ebenezer United Methodist Church, Bowman

Methodist Local Church Records

No abstract provided.