Digital Commons Network^™

A Systematic Review On The Techniques, Long-Term Outcomes, And Complications Of Partial Breast Irradiation After Breast-Conserving Surgery For Early-Stage Breast Cancer, Jing Ning, Guanghui Cheng, Ning Wu

Faculty, Staff and Student Publications

To evaluate the efficacy and safety of four techniques of partial breast irradiation (PBI) including interstitial brachytherapy (ISBT), balloon-based brachytherapy (BBT), Intraoperative radiotherapy (IORT) and three-dimensional conformal radiotherapy (3DCRT) in the treatment for early-stage breast cancer patients after breast-conserving surgery. A systematic search was performed according to the Preferred Reporting Items of Systematic Reviews and Meta-analyses (PRISMA) guidelines using the PubMed, Embase, Cochrane Library and Web of Science databases. The inclusion criteria were clinical trials and observational studies that reported on outcome measures of principal PBI techniques. The methodological quality of the included research data was assessed using bias risk …

An Edge Platform Streamlining Connectivity Between Modern Edge Devices And Cloud, Anderson Carvalho

Theses

The numerous uses of cloud, fog, and edge computing in a variety of industries are thoroughly examined in this thesis, with a special emphasis on smart factories, smart cities, and smart agriculture. It starts with an introduction to cloud computing, going over its history, importance in contemporary digital infrastructures, and related security concerns. It emphasizes the value of cloud computing for processing and storing data while addressing issues like guaranteeing low latency applications and possible improvements from container technologies. The conversation then shifts to fog computing, going over its history, designs, and uses. It focuses on how fog computing might …

"Not A Cookie Cutter Situation": How Neurodivergent Students Experience Group Work In Their Stem Courses, Sophia Salvatore, Claudia White, Stephen Podowitz

College of Life Sciences Faculty Papers

Background: Although group work is increasingly used in STEM courses and may lead to improved academic outcomes, there is evidence that some implementations of group work may lead to unintended barriers for certain students’ learning. Despite the growing number of neurodivergent undergraduate students, there is limited research on neurodivergent students’ experiences with group work in STEM courses. To address this knowledge gap, the current research investigated the experiences of 22 neurodivergent undergraduate students with group work in STEM courses at a range of institution types and in a variety of STEM disciplines. Participants shared experiences with in-class and out-of-class group …

Hawc Observations Of Microquasars As Powerful Particle Accelerators, Xiaojie Wang, Xiaojie Wang, Dezhi Huang, Dezhi Huang, Chang Dong Rho, A. Albert, R. Alfaro, C. Alvarez, A. Andrés, J. C. Arteaga-Velázquez, D. Avila Rojas, H. A. Ayala Solares, R. Babu, E. Belmont-Moreno, T. Capistrán, Y. Cárcamo, A. Carramiñana, F. Carreón

Physics Faculty Research & Creative Works

Micro quasars are one of the classes of powerful Galactic particle accelerators that emit gamma rays beyond multi-TeV energies. Recently, gamma-ray emission above tens of TeV has been detected from some of these objects. The High-Altitude Water Cherenkov (HAWC) observatory has previously reported gamma-ray emission with a median energy of 25 TeV from the micro quasar SS 433, suggesting that gamma-ray binaries can accelerate particles to above 100 TeV inside the jets. With 2,321 days of data and better reconstruction algorithms, the HAWC observatory detected emissions above 20 TeV from two other binaries, V4641 Sagittarii and LS 5039. The V4641 …

Book Review On "Homeopathy For Farm And Garden", Hima Bindu Ponnam

Indian Journal of Research in Homoeopathy

Book review on "Homeopathy for Farm and Garden"

Multimodal Functional Imaging And Clinical Correlates Of Pain Regions In Chronic Low-Back Pain Patients Treated With Spinal Cord Stimulation: A Pilot Study, Yazan Shamli Oghli, Arjun Ashok, Steven Glener, Isaiah Ailes, Mashaal Syed, Kichang Kang, Sara Naghizadeh Kashani, Islam Fayed, Feroze Mohamed, Kiran Talekar, Laura Krisa, Chengyuan Wu, Caio Matias, Mahdi Alizadeh

Department of Radiology Faculty Papers

OBJECTIVE: Spinal cord stimulation (SCS) is an invasive treatment option for patients suffering from chronic low-back pain (cLBP). It is an effective treatment that has been shown to reduce pain and increase the quality of life in patients. However, the activation of pain processing regions of cLBP patients receiving SCS has not been assessed using objective, quantitative functional imaging techniques. The purpose of the present study was to compare quantitative resting-state (rs)-fMRI and arterial spin labeling (ASL) measures between SCS patients and healthy controls and to correlate clinical measures with quantitative multimodal imaging indices in pain regions.

METHODS: Multi-delay 3D …

Ai-Enhanced Decision-Making For Course Modality Preferences In Higher Engineering Education During The Post-Covid-19 Era, Amirreza Mehrabi, Jason Morphew, Babak Nadjar Araabi, Negar Memarian, Hossein Memarian

School of Engineering Education Faculty Publications

The onset of the COVID-19 pandemic has compelled a swift transformation in higher-education methodologies, particularly in the domain of course modality. This study highlights the potential for artificial intelligence and machine learning to improve decision-making in advanced engineering education. We focus on the potential for large existing datasets to align institutional decisions with student and faculty preferences in the face of rapid changes in instructional approaches prompted by the COVID-19 pandemic. To ascertain the preferences of students and instructors regarding class modalities across various courses, we utilized the Cognitive Process-Embedded Systems and e-learning conceptual framework. This framework effectively delineates the …

Sga 56 Senate 2024-09-27 Minutes, Niu Student Government Association Senate

Student Government Association Archives

No abstract provided.

Inorganic Pyrophosphate Plasma Levels In Patients With Ggcx-Associated Pxe-Like Phenotypes, Qiaoli Li, Catherine Troutman, Mary Peckiconis, Tamara Wurst, Sharon Terry

Department of Biochemistry and Molecular Biology Faculty Papers

ntroduction: Pseudoxanthoma elasticum (PXE) is an autosomal recessive ectopic calcification disorder clinically affecting the skin, eyes, and vascular system. Most cases of PXE are caused by inactivating pathogenic variants in the ABCC6 gene encoding a hepatic transmembrane efflux transporter, which facilitates the extracellular release of ATP, the precursor of inorganic pyrophosphate (PPi), a potent endogenous inhibitor of calcification. Pathogenic variants in GGCX, encoding γ-glutamyl carboxylase required for activation of vitamin K-dependent coagulation factors as well as matrix Gla protein (MGP) and Gla-rich protein (GRP), two inhibitors of ectopic calcification, have also been reported to cause cutaneous changes like those seen …

Delusive Nature Of Flip-Flop Sign Secondary To Histoplasmosis, Omer Riyadh, Omron Hassan, Yashwanth Yerramalla

Student Publications

Histoplasmosis, caused by Histoplasma capsulatum, often mimics the appearance of lung cancer on fludeoxyglucose (FDG) positron emission tomography (PET) scans. The “flip-flop fungus,” due to its similar presentation on imaging modalities, can lead to false-positive results and unnecessary invasive testing. We present a 46-year-old male patient with a lung nodule and bilateral hilar lymphadenopathy on an FDG-PET scan who initially presented with chest discomfort. Histoplasma infection was confirmed through Grocott's methenamine silver (GMS) stains on bronchoscopy-guided biopsy specimens. An analysis of additional cases from the literature highlighted the diverse clinical presentations and outcomes associated with this condition that may be …

Evaluation Of The Water Quality And Distribution Of Heavy Metals In The Gomti River Flowing Through The Urban Region Of Lucknow, India, Neha Gondial, Sandhya Bharti

Makara Journal of Science

The physicochemical properties and heavy metals contents of the Gomti River water (GRW) samples collected from five selected sites covering a stretch of ~31 km in Lucknow, Uttar Pradesh, India were ascertained. The sites were Ghaila Pul, Mehndi Ghat, Shaheed Smarak, Kukrail Junction, and Bande Dam, represented as S1, S2, S3, S4, and S5, respectively, following from upstream to downstream. S1 was considered as a reference site. The values of pH, temperature, total dissolved solids (TDS), electrical conductivity (EC), turbidity, dissolved oxygen (DO), biochemical oxygen demand (BOD), total hardness (TH), total chloride (TC), total alkalinity (TA), total acidity (TAC), total …

2024 - Faculty & Staff Research Symposium, Elizabeth Outka, Lidia Radi

Faculty and Staff Research Symposium Programs

[Excerpt from the "Welcome"]

"Dear Colleagues,

Welcome to the second Faculty and Staff Research Symposium!

We are delighted to see such enthusiasm for this event, following the extraordinary response to last year’s inaugural Symposium. It is truly a testament to the vibrant, engaged community we have here — a group of colleagues deeply committed to ideas, creativity, and collaboration. Across our campus, faculty and staff continue to push the boundaries of research, to design and maintain new learning and gathering spaces, to craft remarkable art and performances, and to develop innovative programs that enrich our collective experience. . . . …

Spatial Organization Of Adenylyl Cyclase And Its Impact On Dopamine Signaling In Neurons, Léa Ripoll, Yong Li, Carmen W Dessauer, Mark Von Zastrow

Faculty, Staff and Student Publications

The cAMP cascade is increasingly recognized to transduce physiological effects locally through spatially limited cAMP gradients. However, little is known about how adenylyl cyclase enzymes that initiate cAMP gradients are localized. Here we address this question in physiologically relevant striatal neurons and investigate how AC localization impacts downstream signaling function. We show that the major striatal AC isoforms are differentially sorted between ciliary and extraciliary domains of the plasma membrane, and that one isoform, AC9, is uniquely concentrated in endosomes. We identify key sorting determinants in the N-terminal cytoplasmic domain responsible for isoform-specific localization. We further show that AC9-containing endosomes …

Neuronal Alpha-Synuclein Disease Integrated Staging System Performance In Ppmi, Pasadena, And Spark Baseline Cohorts, Tien Dam, Gennaro Pagano, Michael C Brumm, Caroline Gochanour, Kathleen L Poston, Daniel Weintraub, Lana M Chahine, Christopher Coffey, Caroline M Tanner, Catherine M Kopil, Yuge Xiao, Sohini Chowdhury, Luis Concha-Marambio, Peter Dibiaso, Tatiana Foroud, Mark Frasier, Danna Jennings, Karl Kieburtz, Kalpana Merchant, Brit Mollenhauer, Thomas J Montine, Kelly Nudelman, John Seibyl, Todd Sherer, Andrew Singleton, Diane Stephenson, Matthew Stern, Claudio Soto, Eduardo Tolosa, Andrew Siderowf, Billy Dunn, Tanya Simuni, Kenneth Marek, Parkinson’S Progression Markers Initiative Collaborators

Faculty, Staff and Student Publications

The Neuronal alpha-Synuclein Disease (NSD) biological definition and Integrated Staging System (NSD-ISS) provide a research framework to identify individuals with Lewy body pathology and stage them based on underlying biology and increasing degree of functional impairment. Utilizing data from the PPMI, PASADENA, and SPARK studies, we developed and applied biologic and clinical data-informed definitions for the NSD-ISS across the disease continuum. Individuals enrolled as Parkinson's disease, Prodromal, or Healthy Controls were defined and staged based on biological, clinical, and functional anchors at baseline. Across the three studies 1741 participants had SAA data and of these 1030 (59%) were S+ consistent …

Case Study In Deaf Mental Health Care: Integration Of Therapeutic Attunement And Skills-Training, Julia Ball, Lindsey Sankin

JADARA

Deaf Mental Health Care (DMHC) is a specialty involving clinical expertise and self-awareness in therapeutic work with D/deaf people.1 Within the DMHC framework, this case report describes the psychotherapy of one Deaf individual, whose developmental experiences are common among D/deaf people. It illustrates how clinical models developed with hearing people informed the clinical team working with this Deaf individual. The treatment integrated focused skill-building with reparative emotional and linguistic “attunement.” In addition, the case illustrates how clinicians and their clients can use the intersections of their different languages and cultures as growth opportunities.

Authentication Of Shallots From Brebes Using Gas Chromatography Fingerprinting Technique Combined With Chemometrics, Yana Setyani Pradina, Adelia Puteri, Gina Fauzia Rachma, Nazwa Balqis, Gerli Puspita Anggraini, Hendri Wasito

Makara Journal of Science

Shallots from Brebes, also called Bima Brebes, have a more pungent aroma compared to other varieties. Its high demand results in increased prices in the market, leading to frequent cases of fraud wherein Bima Brebes shallots are replaced with other types of shallots. This study aimed to develop an analytical method using gas chromatography–flame ionization detector (GC-FID) fingerprinting combined with chemometrics to authenticate Bima Brebes shallots. Essential oils were extracted through ultrasonic hydrodistillation, followed by organoleptic, refractive index, GC-FID fingerprinting and chemometric analysis. The yield value of the five studied shallot varieties ranged from 0.02% to 0.08% w/w. Meanwhile, the …

Revealing Ultra-High-Energy Gamma-Ray Emission From The Ehwc J1825-134 Region With Hawc, Dezhi Huang, Dezhi Huang, Hazal Goksu, Hazal Goksu, A. Albert, R. Alfaro, C. Alvarez, A. Andrés, J. C. Arteaga-Velázquez, D. Avila Rojas, H. A. Ayala Solares, R. Babu, E. Belmont-Moreno, T. Capistrán, Y. Cárcamo, A. Carramiñana, F. Carreón, U. Cotti, J. Cotzomi, S. Coutino De Leon, E. De La Fuente, D. Depaoli, C. De Leon, R. Diaz Hernandez, J. C. Diaz-Velez, B. L. Dingus, M. Durocher, M. A. Duvernois, K. Engel, C. Espinoza, K. L. Fan, K. Fang, N. I. Fraija, J. A. Garcia-Gonzalez, F. Garfias, H. Goksu, M. M. Gonzalez, J. A. Goodman, S. Groetsch, J. P. Harding, S. Hernandez, I. Herzog, J. Hinton, D. Huang, F. Hueyotl-Zahuantitla, P. Huntemeyer, A. Iriarte, V. Joshi, S. Kaufmann, D. Kieda, A. Lara, J. Lee, W. H. Lee, H. Leon Vargas, J. Linnemann, A. L. Longinotti, G. Luis-Raya, K. Malone, J. Martinez-Castro, J. A. J. Matthews, P. Miranda-Romagnoli, J. Montes, J. A. Morales-Soto, M. Mostafa, L. Nellen, M. U. Nisa, R. Noriega-Papaqui, L. Olivera-Nieto, N. Omodei, Y. Perez Araujo, E. G. Perez-Perez, A. Pratts, C. D. Rho, D. Rosa-Gonzalez, E. Ruiz-Velasco, H. Salazar, D. Salazar-Gallegos, A. Sandoval, M. Schneider, G. Schwefer, J. Serna-Franco, A. J. Smith, Y. Son, R. W. Springer, O. Tibolla, K. Tollefson, I. Torres, R. Torres-Escobedo, R. Turner, F. Urena-Mena, L. Villasenor, Xiaojie Wang, I. J. Watson, F. Werner, K. Whitaker, E. Willox, H. Wu, H. Zhou

Physics Faculty Research & Creative Works

Located in the southern field of view of the High-Altitude Water Cherenkov (HAWC) observatory, the eHWC J1825-134 region is one of the most complicated gamma-ray emission sites on the galactic plane. The region contains a few PeVatron candidates that can accelerate particles up to PeV energies. Disentangling the overlapping gamma-ray emission and associating it with accelerators is crucial to understand the mechanism of cosmic-ray acceleration and gamma-ray production near the accelerators. In this talk, I will present each of the gamma-ray sources resolved in this region using 1910 days of HAWC data, including their spectra. Also, we have studied their …

Disparities In Stage At Diagnosis Among Hispanic Patients With Gastric Cancer In The United States, Antoine Jeri-Yabar, Liliana Vittini-Hernandez, Renzo Aller-Rojas, Francisco Arias-Reyes, Sirish Dharmapuri

School of Medicine Publications

Simple Summary

This study investigates racial disparities in the stage of gastric cancer at diagnosis and overall survival among different racial groups using data from the SEER database (2018–2021). The retrospective cohort study of 18,984 patients found that Hispanics are 19% more likely to be diagnosed at a later stage of gastric cancer compared to non-Hispanics. Additionally, both Hispanics and Black patients showed poorer overall survival compared to Non-Hispanic Whites. The disparities are attributed to factors such as healthcare access, insurance coverage, language barriers, and preventive health service utilization. These findings highlight the need for targeted interventions to address these …

Front-End Computational Modeling And Design For The Antarctic Demonstrator For The Advanced Particle-Astrophysics Telescope, Marion Sudvarg, Ye Htet, Roger Chamberlain, Jeremy Buhler, Blake Bal, Blake Bal, Corrado Altomare, Corrado Altomare, Davide Serini, Davide Serini, Mario Nicola Mazziotta, Mario Nicola Mazziotta, Leonardo Di Venere, Leonardo Di Venere, Wenlei Chen, Wenlei Chen, James H. Buckley, Roger D. Chamberlain

Computer Science Faculty Research & Creative Works

The Advanced Particle-astrophysics Telescope (APT) is a planned space-based observatory designed to localize MeV to TeV transients such as gamma-ray bursts in real time using onboard computational hardware. The Antarctic Demonstrator for APT (ADAPT) is a prototype high-altitude balloon mission scheduled to fly during the 2025–26 season. Gamma-ray-induced scintillations in CsI tiles will be captured by perpendicular arrays of optical fibers running across both tile surfaces, as well as SiPM-based edge detectors to improve light collection and calorimetry. Signal samples are captured by analog waveform digitizer ASICs then sent to the front end of the computational pipeline, which is designed …

Noninvasive Multi-Cancer Detection Using Blood-Based Cell-Free Micrornas, Jason Zhang, Hallgeir Rui, Hai Hu

Department of Pharmacology, Physiology, and Cancer Biology Faculty Papers

Patients diagnosed with early-stage cancers have a substantially higher chance of survival than those with late-stage diseases. However, the option for early cancer screening is limited, with most cancer types lacking an effective screening tool. Here we report a miRNA-based blood test for multi-cancer early detection based on examination of serum microRNA microarray data from cancer patients and controls. First, a large multi-cancer training set that included 1,408 patients across 7 cancer types and 1,408 age- and gender-matched non-cancer controls was used to develop a 4-microRNA diagnostic model using 10-fold cross-validation. In three independent validation sets comprising a total of …

Usf2 And Tfeb Compete In Regulating Lysosomal And Autophagy Genes, Jaebeom Kim, Young Suk Yu, Yehwa Choi, Do Hui Lee, Soobin Han, Junhee Kwon, Taichi Noda, Masahito Ikawa, Dongha Kim, Hyunkyung Kim, Andrea Ballabio, Keun Il Kim, Sung Hee Baek

Duncan NRI Faculty and Staff Publications

Autophagy, a highly conserved self-digestion process crucial for cellular homeostasis, is triggered by various environmental signals, including nutrient scarcity. The regulation of lysosomal and autophagy-related processes is pivotal to maintaining cellular homeostasis and basal metabolism. The consequences of disrupting or diminishing lysosomal and autophagy systems have been investigated; however, information on the implications of hyperactivating lysosomal and autophagy genes on homeostasis is limited. Here, we present a mechanism of transcriptional repression involving upstream stimulatory factor 2 (USF2), which inhibits lysosomal and autophagy genes under nutrient-rich conditions. We find that USF2, together with HDAC1, binds to the CLEAR motif within lysosomal …

The Association Of The Oral Microbiota With Cognitive Functioning In Adolescence, Oxana Y Naumova, Pavel V Dobrynin, Galina V Khafizova, Elena L Grigorenko

Faculty, Staff and Students Publications

Background: A growing body of research supports the role of the microbial communities residing in the digestive system in the host's cognitive functioning. Most of these studies have been focused on the gut microbiome and its association with clinical phenotypes in middle-aged and older adults. There is an insufficiency of population-based research exploring the association of normative cognitive functioning with the microbiome particularly with the oral microbiota.

Methods: In this study, using metagenomics and metabolomics, we characterized the salivary microbiome diversity in a sample of 51 males of Hispanic and African American origin aged 12-18 years and explored …

“What Keeps Me In School”: Oregon Bipoc Learners Voice Support That Makes Higher Education Possible, Roberta Hunte, Miranda Mosier-Puentes, Gita Mehrotra, Eva Skuratowicz

School of Social Work Faculty Publications and Presentations

A growing number of college students are nontraditional learners (age 21–65) who are people of color. These students face unique challenges in a higher education system increasingly shaped by neoliberalism and the ongoing context of institutionalized racism. In Oregon, policymakers have established ambitious goals to address racial disparities in educational attainment. In this study, focus groups and interviews were conducted with 111 Black, Indigenous, and People of Color (BIPOC) adult learners in Oregon to better understand their perspectives and experiences in regard to educational and career pathways. Participants included currently enrolled students, adults who had enrolled and left, and adults …

Prevalence Of Cardiometabolic Risk Factors In Women: Insights From The Houston Heartreach Study, Arjun R Raghuram, Matthew W Segar, Stephanie Coulter, Joseph G Rogers

The Texas Heart Institute Journal

BACKGROUND: Cardiovascular disease is the leading cause of death among women in the United States. Past research has highlighted the importance of the relationship between female-specific demographics and traditional risk factors. The present analysis aimed to identify the prevalence of modifiable risk factors in women attending a community cardiovascular health screening.

METHODS: Data collected between 2011 and 2019 were obtained from the Houston HeartReach Registry. Participants were classified as having or not having each of 4 traditional cardiometabolic risk factors: hypertension, diabetes, body mass index indicating overweight or obesity, and dyslipidemia. Differences in prevalence were compared using the Pearson χ2 …

Thinking Outside The Book Box, Michael Lewis, Stephanie Chinn

University Libraries Faculty Research & Creative Works

No abstract provided.

Spartan Daily, September 26, 2024, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2024

Volume 163, Issue 15

The Indiana Statesman, September 26, 2024, Indiana State University

Student Newspaper

Richard Goodall wins America’s Got Talent; Terre Haute Pride Festival on Indiana State Campus; Donation to School of Nursing; Cunningham celebrates banned and challenged books

The Rattler (Volume 113, Issue 2), St. Mary's University

The Rattler (Previous issues)

Founded in 1919, The Rattler is the student voice of St. Mary’s University in San Antonio, Texas. The newspaper documents campus life, academic and social issues, student opinion, and local and national events as they relate to the University community. Content typically includes news articles, editorial commentary, arts and culture coverage, sports reporting, and advertisements.

The Legal Protection For Refugees In The Sultanate Of Oman., Abdelnaser Aljahani, Saif Al Rawahi

Sultan Qaboos University Legal Studies Journal

The Sultanate of Oman is not a State party to the 1951 Convention relating to the Status of Refugees (the 1951 Refugee Convention) and its 1967 Protocol, which establish refugee rights and obligations. In addition, there are no specific national laws or administrative regulations governing the right to asylum. However, the Basic Statute of the Sultanate of Oman and the Foreign Residency Law in Oman explicitly grant the right to asylum to a specific category of individuals, who are political refugees. The Basic Statute of Oman refers to political asylum briefly, while the Foreign Residency Law in Oman includes several …

Research Priorities For Childhood Apraxia Of Speech: A Long View, Patricia Mccabe, Molly Beiting, Elaine R Hitchcock, Edwin Maas, Amy Meredith, Angela T Morgan, Nancy L Potter, Jonathan L Preston, Laura Moorer, Pooja Aggarwal, Kirrie Ballard, Laura Baskall Smith, Nicole F Caballero, Kathryn Cabbage, Julie Case, Susan Caspari, Karen V Chenausky, Shina Cook, Ewa Grzelak, Maryane Gomez, Aubrie Hagopian, Chantelle Highman, Anne Hodits, Jenya Iuzzini-Seigel, Jillian Levos-Carlson, Barbara A Lewis, Patricia Mayro, Jyutika Mehta, Gabrielle Miller, Kimberly D Mory, Elizabeth Murray, Megan S Overby, Lucia Pasquel-Lefebvre, Derrick Peavy, Caitlin V Raaz, Brooke Rea, Denise Santos Ford, Lynn Smith, Michelle T. Swartz, Melissa Taberski, Hayo Terband, Donna C Thomas, Hannah Valentine, Mirjam Van Tellingen, Shelley Velleman, Emily Wang, Sarah White, Eddy C H Wong, Maria I Grigos

Department of Speech-Language Pathology Faculty Papers

This article introduces the Journal of Speech, Language, and Hearing Research Special Issue: Selected Papers From the 2022 Apraxia Kids Research Symposium. The field of childhood apraxia of speech (CAS) has developed significantly in the past 15 years, with key improvements in understanding of basic biology including genetics, neuroscience, and computational modelling; development of diagnostic tools and methods; diversity of evidence-based interventions with increasingly rigorous experimental designs; and understanding of impacts beyond impairment-level measures. Papers in this special issue not only review and synthesize the some of the substantial progress to date but also present novel findings addressing critical research …