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Mapping And Modeling Threat-Evoked Brain States After Early Life Adversity, Taylor W. Uselman

Biomedical Sciences ETDs

Early life adversity (ELA) increases lifelong neuropsychiatric vulnerability. Yet how ELA reorganizes brain-wide activity and circuit coordination across later experience remains unclear. This dissertation tests the hypothesis that ELA alters adult brain-wide activity and responses to threat through disrupted coordination among neural systems that regulate emotional experience, including prefrontal-limbic and monoaminergic systems. Longitudinal manganese-enhanced MRI of adult mice exposed to standard or fragmented early care, combined with computational processing and statistical modeling, quantified brain states before, during, and long after innate predator threat. These studies established that acute threat evokes large-scale, distributed brain activity that evolves over time. ELA potentiates …

Prenatal Alcohol Exposure Induces Vulnerability To Mild Stress Through Heightened Limbic Glial Activation And Cytokine Release, Justine R. Zimmerly

Biomedical Sciences ETDs

Fetal alcohol spectrum disorder (FASD) results from prenatal alcohol exposure (PAE) and is linked to development of mood disorders, which in turn are driven by dysregulation of the sympathetic nervous system, the neuroendocrine hypothalamic-pituitary-adrenal (HPA) axis, and the central nervous system (CNS) neuroimmune response to stressors. PAE alters brain glial activation and proinflammatory cytokine expression through secondary challenges such as psychological stressors. The goals of the experiments presented in this dissertation were to 1) examine peripheral glucocorticoid receptor function following mild acute stress in adult PAE offspring, 2) characterize a sensitized cytokine stress response in the hippocampus, medial prefrontal cortex, …

Co-Constructing The Common Ground: Responses In American Sign Language Conversation, Deborah Wager

Linguistics ETDs

Common ground between two people consists of the things they both know, that they know they both know. This body of knowledge grows in conversation, through both verbal and nonverbal responses. Responses communicate whether what has been said was accepted into the common ground, and return responses acknowledge this acceptance in turn (H. H. Clark, 1996). In addition to the semantic content of utterances, stance is communicated through a variety of means, and alignment with that stance is also communicated through responses.

This study explores ways in which responses are used in American Sign Language (ASL) conversation to co-construct the …

Documenting Regional And Individual Variation In Taiwan Sign Language, Devin Alexander Tankersley

Linguistics ETDs

Taiwan Sign Language (TSL) has been characterized by a north-south dialectal divide since the beginning of its development in the early twentieth century, further complicated by contact with Chinese Sign Language and with Mandarin. Considering increased interconnectivity across Taiwan, this dissertation asks: does the traditional north-south dialectal distinction still hold? To address this question, fieldwork was conducted across six areas of Taiwan to develop a data set consisting of word elicitations and sociolinguistic interviews. Findings from quantitative and qualitative analyses of these data suggest that TSL is not undergoing straightforward dialect leveling, but rather convergence towards a mixed variety shaped …

Surveyception: An Exploration Of Deceptive Survey Forms, Muhammad Danish

Computer Science ETDs

Survey platforms such as Google Forms and Microsoft Forms are widely used for feedback, data collection, and engagement, but scammers increasingly exploit them to distribute phishing and deceptive attacks. This thesis presents a large-scale study of survey-form abuse across ten major providers. We collected 140,000 forms from three sources: public posts on X, search-engine results, and web pages from the top 10 million DomCop-ranked domains. Using automated filtering and manual qualitative review, we identified 2,645 forms requesting sensitive information and classified 566 as scams. These forms used techniques including phishing, private-secret theft, account and personal-data harvesting, financial deception, and psychological …

Myeloid Mmp14 Couples Extracellular Proteolysis To Inflammatory And Metabolic Remodeling During Obesity, Long J Shao, Fathima Elizondo, Feng Gao, Elizabeth L Lieu, Bharati Reddi, Maryam Elizondo, Iqbal Mahmud, Kristin Eckel-Mahan, Philipp E Scherer, Xin Ge, Huaizhu Wu, Sean Hartig, Kai Sun

The Brown Foundation: Institute of Molecular Medicine

Macrophages orchestrate tissue remodeling, inflammation, and metabolic dysfunction in obesity, but the role of macrophage-intrinsic extracellular proteolysis in immunometabolic regulation remains unclear. Matrix metalloproteinase-14 (MMP14), a membrane-bound protease, is strongly induced during monocyte-to-macrophage differentiation and further elevated in adipose tissue macrophages from high-fat diet (HFD)-fed mice. Pharmacological inhibition or myeloid-specific deletion of Mmp14 impaired macrophage differentiation, proliferation, migration, phagocytosis, and inflammatory activation in response to obesity-associated adipose tissue signals. Mechanistically, MMP14 promoted inflammatory programming by increasing endotrophin generation and enhancing TLR4-NFκB signaling. MMP14 also reprogrammed macrophage lipid metabolism by suppressing lipolysis and promoting lipid accumulation, altering metabolic communication with neighboring …

Good Impressions At Work: Exploring Gendered Labor In The Middle Rio Grande, Nm Ad 1100-1500, William F. Marquardt

Anthropology ETDs

This dissertation investigates changes in the gendered division of labor among potters in the Middle Rio Grande Valley, New Mexico (MRG) between A.D. 1100 and 1500. During this time, diverse groups coalesced into some of the largest communities seen in the region until the industrial era. New architectural, technological, religious, and trade practices emerged to help knit these communities together during a dynamic period of change. Pottery making practices changed alongside other developments transforming from manufacture for local consumption to surplus production for exchange. Previous research on gendered divisions of labor have largely portrayed gendered labor as static rather than …

You Can't Teach Kids From A Book: Language, Authority And Revitalization In Jicarilla Apache Life, Mariann Skahan

Anthropology ETDs

This dissertation examines how Jicarilla Apache is learned, taught, and used across community life, with particular attention to contemporary language revitalization. Based on ethnographic research with elders, educators, language workers, families, and community institutions, it follows language practices across classrooms, culture camps, homes, ceremonial settings, and collaborative archival projects. I show that linguistic knowledge does not carry the same authority or consequences in every setting. Words may be recognized without being taken up, speakers may possess linguistic knowledge without being authorized to teach or correct, and archival texts may preserve linguistic forms without preserving the relations needed to interpret and …

New Distance Distributions Of Asymptotic Giant Branch Stars And Their Role In Tracing Galactic Structure, Rajorshi Bhattacharya

Physics & Astronomy ETDs

Asymptotic giant branch (AGB) stars are among the final evolutionary stages of low- and intermediate-mass stars and among the most luminous cool stellar populations in the Milky Way (MW). Their strong infrared emission allows them to be observed through regions of high interstellar extinction, making them useful tracers of the inner MW. However, their use is limited by unreliable distances because many are dust-obscured and variable, while geometric parallaxes are often unavailable or uncertain. This thesis develops statistical distance-estimation methods for large samples of oxygen-rich AGB stars. The resulting distances broadly agree with literature estimates, supporting their statistical reliability for …

Extending The Discovery Space Of Tess: Probing Underexplored Exoplanet Populations, Mallory L. Harris

Physics & Astronomy ETDs

This dissertation investigates how cold exoplanets can be identified despite the strong observational bias of exoplanet surveys toward short-period systems. Planets at wider orbital separations remain comparatively poorly constrained, limiting tests of planetary-system formation and the prevalence of outer architectures beyond compact systems. To address this gap, I use two complementary approaches. First, I develop a transit-search pipeline for TESS Full-Frame Images that identifies both isolated and repeated transit-like signals around nearby M dwarfs and characterizes the dominant false-positive classes that limit sensitivity in this regime. I then present TOI-904 c, the coldest planet discovered by TESS around an M …

An Investigation Of Tess M&Ms And The Occurrence Rate Of Transiting Circumbinary Planets, Dominic Oddo

Physics & Astronomy ETDs

Circumbinary planets (CBPs) are worlds which orbit two stars simultaneously. CBPs are excellent tests of the tenacity of planet formation, but are difficult to detect. The space-based NASA Transiting Exoplanet Survey Satellite (TESS) mission is a nearly all-sky survey designed to detect exoplanets transiting nearby stars. In this dissertation, I analyze the performance of TESS by comparing to the photometric precision of the ESA CHEOPS mission. Then, I define a catalog of low-mass eclipsing binaries (M&Ms), which are the best sources to search for CBPs. I describe my custom transit search methodology and apply it to the M&M catalog. I …

Simulating Quantum Field Theories On Fault-Tolerant Quantum Computers, Mason L. Rhodes

Physics & Astronomy ETDs

Quantum field theories are an essential framework in modeling fundamental interactions in nature, yet reliable simulations consume large portions of the world's most powerful supercomputers. In this Dissertation, we explore an alternative simulation paradigm on fault-tolerant quantum hardware, discussing both algorithmic and model advancements. In the former, we construct state-of-the-art algorithmic subroutines that take advantage of useful properties of the Hamiltonian describing the theory to achieve an exponential improvement in resources over prior quantum algorithms. In the latter, we simplify the structure of the Hamiltonian, making it more amenable to quantum simulation. First, we present an improved regularization of the …

Strategies For Large Dynamic Range, Entanglement-Enhanced Quantum Metrology With Experimentally Demonstrated Resources, Tyler G. Thurtell

Physics & Astronomy ETDs

Quantum metrology studies the use of quantum mechanical systems as measurement devices or sensors. Surprisingly, preparing a sensor in an entangled state can enhance measurement precision. The simplest protocols for entanglement enhancement sense only small changes in a quantity. The range of values over which a measurement protocol works is called its dynamic range. For many types of sensors we require end-to-end protocols that describe how to use entanglement to achieve enhanced precision over a large dynamic range. In this dissertation, we describe two approaches to achieving entanglement-enhanced sensing over a large dynamic range. The first approach uses entangling resources …

Quantum Control Of Qubits And Qudits In Neutral Atom Systems, Sri Datta Vikas Buchemmavari

Physics & Astronomy ETDs

This dissertation explores control of neutral atom quantum systems across multiple levels of abstraction, from atomic physics to system-level fault tolerance, using optimal control to improve performance. First, we propose a Rydberg entangling gate based on dressing with only the qubit control field; an interaction energy near the Rabi frequency benefits both gate speed and Rydberg decay. Second, with Sandia National Laboratories, we show that leakage errors in neutral atom systems can be converted to atom loss errors and detected using two entangling gates with an auxiliary atom, where a SWAP-based leakage detection unit outperforms the standard design. Next, we …

Naturalistic Aided Language Intervention For Children Who Have Multiple Disabilities Including Visual Impairment, Naomi Nattress

Speech and Hearing Sciences ETDs

ABSTRACT

This dissertation examined aided AAC interventions for individuals with multiple disabilities, including visual impairment, across three original studies. Chapter 2, a meta-analysis, found limited rigorous research for this population while showing that individuals at early symbolic stages with diverse visual profiles can successfully engage with AAC when appropriate adaptations are provided. The pilot study in Chapter 3 indicated that caregivers and graduate student clinicians can learn and implement naturalistic AAC techniques and VI accommodations with high fidelity through structured coaching. The mixed methods study in Chapter 4 introduced the ImPAACT-VI program, showing strong outcomes in educator performance, students’ symbolic …

Recovery Through Connection: The Role Of Positive Social Interactions In Early Alcohol And Opioid Recovery Outcomes, Hannah Avery Carlon

Psychology ETDs

Recovery from substance use disorder (SUD) is influenced by both positive emotional functioning and social connectedness. However, empirical research has yet to examine how these two protective factors interact to influence recovery. The present study aimed to address this gap by exploring positivity resonance, or the shared experience of positive emotions, in the first year of recovery. In Aim 1, we examined change trajectories of positivity resonance and recovery capital over the first year of recovery among adults with alcohol use disorder (AUD; n=470) and opioid use disorder (OUD; n=61), the associations between these change trajectories (1a), and …

Understanding The Long-Run Effect Of Historical Redlining Practices, Yujian Lu

Geography ETDs

Historical redlining practices initiated by Home Owners’ Loan Corporation (HOLC) in the 1930s have produced enduring persistent socioeconomic and environmental disparities in U.S. cities. This dissertation examines their long-term impacts on social vulnerability, urban flood risk, along with public discourse about redlining practices. Results indicate that neighborhoods with HOLC grade A (greenlined) exhibit the lowest overall social vulnerability, while those graded D (redlined) face the highest across U.S. cities. In Chicago, associations between redlining practices and flood risk disparities are stronger than in Los Angeles, reflecting place-specific characteristics among environmental, socioeconomic, and demographic factors shaping flood risk disparities in long …

How Forest Structure And Climate Influence Snowpack For Water Resources In The Southwestern United States, Lindsey L. Rotche

Geography ETDs

Climate change, declining snowpack, and increasing wildfire risk have profound impacts on water availability in the southwestern United States. Because the southwestern United States is a global hotspot for freshwater vulnerability, and snowpack provides much of the region’s freshwater, understanding how climate and forest structure influence snowpack dynamics is increasingly important. In this dissertation I aim to better understand and communicate these dynamics through empirical data collection and the development of a simple vegetation driven temperature-index snow model: SNOW-17(VEG). I then implement the model at a watershed scale using remotely sensed imagery to create vegetation zones and climate simulations to …

Reading The Martian Surface: Impact Crater Distributions And Geochemical Signatures In Gale Crater As Recorded By The Curiosity Rover, Megan E. Hoffman

Earth and Planetary Sciences ETDs

The Curiosity rover has been exploring Gale crater, a large impact basin near the Mars equator since 2012. This mission has greatly improved our ability to explore the surface of Mars with a suite of geologic tools and cameras and has revealed that Mars likely once resembled present-day Earth. In this dissertation, I utilize measurements and data taken by Curiosity to analyze the distribution and preservation of small impact craters at meter scales, I quantify the formation characteristics of a small impact crater cluster, and I examine the presence of barium in a geologic unit with high-Si to constrain sediment …

Regenerative Writing: The Rhetorics Of Indigenous Futurisms As Pedagogical Praxis, Madeline R. Mendoza

English Language and Literature ETDs

This dissertation explores how land-based writing and Indigenous Futurisms can reshape writing pedagogy in higher education, focusing on English courses at the University of New Mexico. At the center of this project is the Land Memoirs assignment, which I designed to encourage students to engage land as a living relative and active participant in the learning process. Through the frameworks of Indigenous Futurisms, Land as Pedagogy, Rhetorical Sovereignty, and Pueblo understandings of marking, I analyze the rhetorical choices across student multimodal narratives, reflections, and interviews to examine the assignment’s pedagogical impact. My findings reveal epistemic differences in how Indigenous …

Algorithmic Sculpting Of Complex Fused Silica Surfaces For Nondestructive, Mode-Matched Cavity Quantum Electrodynamics: Adaptive Co2 Milling And Simulation-Guided Ultrafast Inscription, From Fiber Fabry-Perot Cavities To Monolithic Architectures, Meagan E. Parker

Optical Science and Engineering ETDs

Quantum sensors achieve exceptional measurement sensitivity through coherent, well-isolated quantum systems, but practical deployment is hindered by destructive readouts that require repeated state preparation and create long system dead times. Optical cavities enable continuous, nondestructive measurements with minimal back-action, yet integrating high-finesse cavities into scalable quantum devices remains limited by existing fabrication methods. To overcome these constraints, an adaptive CO₂ laser-milling platform was developed. Guided by glass thermodynamics and melt dynamics, this closed-loop system uses in-situ phase-shifting interferometry to sculpt complex fused-silica surfaces with sub-nanometer root-mean-square roughness. The platform was validated by fabricating extended-length fiber Fabry–Pérot cavities and monolithic micro-cavity …

Non-Traditional Rare-Earth-Doped Oxide Glass As A Gain Medium, Jared S. Tolliver

Optical Science and Engineering ETDs

There is a need for mid-infrared(MIR) lasers in defense, medical, and environmental monitoring. A large part of this technological development is the study of gain media. One class of materials of special interest is glasses with a low maximum phonon energy. These have the fiberization and broad spectral features of glass, whereas glasses with high maximum phonon energy exhibit higher rates of multi-phonon relaxation and can be opaque in the MIR, both of which are detrimental to laser operation. Recent advances in container-less processing have allowed for the study of new glasses that aren’t possible with conventional fabrication techniques. One …

Keeping Communities Safe Through An Alternative First Response Model: Predictors Of Civilian First Responders’ Self-Efficacy In Handling Crisis Situations, Jasmine Desiderio

Organization, Information and Learning Sciences ETDs

The expansion of civilian alternative first responder models reflects a national shift toward community-based approaches to crisis intervention. Grounded in Albert Bandura’s social learning theory, this study examined the extent to which demographic characteristics are associated with crisis self-efficacy, explored how perceptions of the responder role relate to confidence, and identified supports necessary for effective crisis response. A convergent parallel mixed-methods design was employed with civilian first responders in Albuquerque, New Mexico. Quantitative data were collected with the Crisis Self-Efficacy Scale, and semi-structured interviews gathered qualitative data. Exploratory regression analyses (n=31) were not reliably associated with crisis self-efficacy, while role …

Transforming Faculty Development: Organizational Citizenship Behavior, Arts-Based Design, And Communities Of Transformation In Stem Education, Kristen L. Ferris

Organization, Information and Learning Sciences ETDs

This dissertation investigates the relational conditions enabling institutional transformation and diversity, equity, inclusion, and justice (DEIJ) within STEM higher education. Despite needs for systemic change, sustaining faculty engagement remains difficult due to entrenched power dynamics, lack of pedagogical training, and political repression. To address these barriers this research introduces Organizational Citizenship Behaviors (OCB) as an analytic lens and functional infrastructure for change.

Through three papers, this study 1) establishes OCB via a systemic literature review as an actionable metric for faculty development; 2) details the design of a cross-institutional Community of Transformation (CoT) as a design case; and 3) Presents …

Real-Time Waveform Synthesis For Rfsoc-Based Quantum Control Systems, Tiamike I. Dudley

Electrical and Computer Engineering ETDs

RFSoCs are gaining adoption in many labs for quantum control systems thanks to their compactness and affordability. Making full use of the many components on an RFSoC evaluation board is a challenging engineering problem that must be solved to realize scalable control systems. In this dissertation, I evaluate the performance of various RFSoC components in the context of quantum information science. I present two custom FPGA engines that accelerate and parallelize arbitrary waveform generation. The first engine can be instantiated many times to power low-speed DACs for ion-shuttling trap electrodes. The second engine synthesizes CPMG-XY8n dynamical decoupling pulse sequences on …

Modeling For You: A Personalized Approach To Residential Energy Simulation And Distributional Reinforcement Learning, Nestor Gabriel Pereira

Electrical and Computer Engineering ETDs

The growing complexity and uncertainty of residential energy use, driven by electric

vehicles and renewable technologies, demand more intelligent and robust

management systems. Traditional methods often fail when faced with unpredictable

electricity prices and user behavior. This dissertation addresses this gap by presenting

a novel personalized framework combining detailed household energy modeling with

a risk-aware reinforcement learning agent for appliance scheduling.

The first contribution is a probabilistic, bottom-up simulation model that captures

the interdependent behaviors of occupants, appliances, and electric vehicles to

generate realistic, high-fidelity load profiles. The second contribution is a lightweight,

tabular Distributional Q-Learning (D-QL) algorithm that schedules …

Multi-Robot Cooperative System For Complex Aerospace Manipulation Tasks: Theory And Application, Longsen Gao

Electrical and Computer Engineering ETDs

Multi-robot systems can extend manipulation capabilities beyond the limits of a single robot, particularly for tasks involving large, flexible, delicate, or free-floating payloads. Reliable cooperative manipulation, however, remains difficult when payload dynamics, contact geometry, compliance properties, deformation-induced forces, and external disturbances are only partially known, and when safety constraints must be enforced during physical interaction. This dissertation develops a two-layer control framework for resilient multi-robot manipulation under uncertainty, with emphasis on space servicing, satellite stabilization, aerial transportation, and cooperative manipulation of free-floating structures.

The Dental Hygienist Perspective On Laser Use For Nonsurgical Periodontal Therapy, Tammie A. Nyce Mrs.

Dental Hygiene ETDs

The purpose of this study was to assess the perceptions, attitudes, and experiences of dental hygienists regarding the use of lasers in the non-surgical treatment of periodontal disease.  A descriptive survey was distributed via email to current active and inactive members of the American Dental Hygienists’ Association. The sample consisted of practicing dental hygienists who had received training in laser use and lived in states that allowed laser use by dental hygienists.   Those dental hygienists who are not practicing clinically, who are not trained in the use of lasers, and who do not have experience using lasers in the treatment …

Measurements And Studies For Rare Event Searches Using Directional Detectors, Elizabeth Tilly

Physics & Astronomy ETDs

Measuring topology and initial direction of low-energy (keV-MeV) particle tracks is interesting to rare-event searches. While directional dark matter searches have been one of the largest drivers for R&D for low-energy directional detectors, this work is interested in its application to Migdal searches. The Migdal effect—a nuclear recoil and an electron recoil sharing a vertex—has been used as a detection channel for low-mass dark matter but has only recently been measured. Low-energy directional detectors are ideal to measure the canonic Migdal topology. This dissertation discusses 3D reconstruction algorithms developed for the Migdal In Galactic Dark mAtter expLoration (MIGDAL) experiment and …

Exploring The Role Of A Mushy, Crustal Compliant Region In Volcano Deformation, Grant A. Block

Physics & Astronomy ETDs

Volcanoes are both creative and destructive forces that have shaped and continue to shape our world from early geologic time to the present day. Continued study of volcanic processes not only better prepares us for monitoring volcanic hazards but also allows us to better understand processes fundamental to Earth as we know it, such as the generation of the atmosphere and accretion of the continents. This dissertation focuses on an integral part of volcanic processes: the trans-crustal magmatic transport system. Specifically, we investigate regions of these transport systems where magma pools in melt-rich lenses within broader regions of low melt-fraction, …