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Diabetes

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Prevention Of Diabetes-Related Hospital Readmission Following Initial Diagnosis Of Diabetes In Patients Over The Age Of Fifty: A Scoping Review, Nathan Miller Dnp, Agacnp, Fnp, Jasmine Harris Dnp, Fnp, Michael Clardy Dnp, Agacnp, Diana Dedmon Dnp, Acnp, Fnp-Bc Apr 2022

Prevention Of Diabetes-Related Hospital Readmission Following Initial Diagnosis Of Diabetes In Patients Over The Age Of Fifty: A Scoping Review, Nathan Miller Dnp, Agacnp, Fnp, Jasmine Harris Dnp, Fnp, Michael Clardy Dnp, Agacnp, Diana Dedmon Dnp, Acnp, Fnp-Bc

Doctor of Nursing Practice Projects

Purpose/Background: By reviewing multiple studies related to the treatment of patients with new diagnoses of diabetes, this scoping review will endeavor to determine which interventions, when implemented for patients over 50 years old which are newly diagnosed with type 2 diabetes, can decrease the likelihood of hospital readmission related to diabetes within 90 days when compared with those patients who did not receive or participate in follow-up.

Methods: For resources to be eligible to review they had to be from 2015 or after. Studies selected included patients over the age of 50 newly diagnosed with type 2 diabetes subject to …


Review Of Diabetes Among Aboriginal And Torres Strait Islander People, Katherine Ride, Samantha Burrow Apr 2022

Review Of Diabetes Among Aboriginal And Torres Strait Islander People, Katherine Ride, Samantha Burrow

Journal of the Australian Indigenous HealthInfoNet

Diabetes is the fastest growing chronic disease condition globally. Type 2 diabetes in particular, has reached epidemic proportions, with the greatest burden falling on socially disadvantaged groups and Indigenous peoples.

This review focuses primarily on type 2 diabetes among Aboriginal and Torres Strait Islander people, which is responsible for the majority of cases of diabetes in this population. It provides general information on the social and cultural context of diabetes, and the behavioural and biomedical factors that contribute to diabetes among Aboriginal and Torres Strait Islander people.

This review provides detailed information on:

  • the extent of diabetes among Aboriginal and …


Your Body On Sugar, Jennifer Haltli Apr 2022

Your Body On Sugar, Jennifer Haltli

Children's Book and Media Review

Grab a cookie before you sit down to read, but you may find yourself switching to strawberry as you learn about the natural role of, and misuses of, sugar. Beginning with an exploration of sugar and how it is processed by the body, readers will get a lesson in agriculture regarding how sugar is grown. You also learn that there are natural foods that contain sugar, but added sugars and snack foods contribute to dental and diabetic disorders that accompany the fanatical consumption of sugar in modern diets. In the end, it’s important you remember that you can enjoy sugar …


Evaluating Fidelity To The National Extension Dining With Diabetes Program: Challenges And Opportunities, Laura E. Balis, Bailey Houghtaling, Julie Harker Buck Apr 2022

Evaluating Fidelity To The National Extension Dining With Diabetes Program: Challenges And Opportunities, Laura E. Balis, Bailey Houghtaling, Julie Harker Buck

Journal of Human Sciences and Extension

The objective of this study was to evaluate fidelity to the Dining with Diabetes (DWD) program. Data were gathered cross-sectionally in 2019 using class profile forms (i.e., checklists) containing items reflecting the core components of DWD: delivery personnel, curriculum, hands-on cooking, and goal setting. Fidelity was calculated as the proportion of core components completed as intended. Educators (N = 9) completed class profile forms for 10 complete DWD programs (i.e., all four classes). Fidelity to components of completed DWD programs and individual DWD classes was high (over 70% in each category). Overall, fidelity was high, and adaptations reported likely did …


Associations Of Steps Per Day And Step Intensity With The Risk Of Diabetes: The Hispanic Community Health Study / Study Of Latinos (Hchs/Sol)., Carmen C. Cuthbertson, Christopher C. Moore, Daniela Sotres-Alvarez, Gerardo Heiss, Carmen R. Isasi, Yasmin Mossavar-Rahmani, Jordan A. Carlson, Linda C. Gallo, Maria M. Llabre, Olga L. Garcia-Bedoya, David Goldsztajn Farelo, Kelly R. Evenson Apr 2022

Associations Of Steps Per Day And Step Intensity With The Risk Of Diabetes: The Hispanic Community Health Study / Study Of Latinos (Hchs/Sol)., Carmen C. Cuthbertson, Christopher C. Moore, Daniela Sotres-Alvarez, Gerardo Heiss, Carmen R. Isasi, Yasmin Mossavar-Rahmani, Jordan A. Carlson, Linda C. Gallo, Maria M. Llabre, Olga L. Garcia-Bedoya, David Goldsztajn Farelo, Kelly R. Evenson

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: Higher levels of moderate-to-vigorous physical activity have been associated with a lower risk of diabetes, but less is known about how daily step counts (steps/day) are associated with diabetes risk. Therefore, we examined the association of steps/day and step intensity with incident diabetes.

METHODS: We included 6634 adults from the population-based prospective cohort Hispanic Community Health Study/Study of Latinos (HCHS/SOL) (2008-2017). Cox proportional hazard models that accounted for complex survey design and sampling weights were used to estimate the association of baseline accelerometer-assessed steps/day and step intensity with 6-year risk of incident diabetes as hazard ratios (HR) and 95% …


Association Between Non-Tea Flavonoid Intake And Risk Of Type 2 Diabetes: The Australian Diabetes, Obesity And Lifestyle Study, Mary D. Adu, Catherine P. Bondonno, Benjamin H. Parmenter, Marc Sim, Raymond J. Davey, Kevin Murray, Simone Radavelli Bagatini, Dianna J. Magliano, Robin M. Daly, Jonathan E. Shaw, Joshua R. Lewis, Jonathan M. Hodgson, Nicola P. Bondonno Apr 2022

Association Between Non-Tea Flavonoid Intake And Risk Of Type 2 Diabetes: The Australian Diabetes, Obesity And Lifestyle Study, Mary D. Adu, Catherine P. Bondonno, Benjamin H. Parmenter, Marc Sim, Raymond J. Davey, Kevin Murray, Simone Radavelli Bagatini, Dianna J. Magliano, Robin M. Daly, Jonathan E. Shaw, Joshua R. Lewis, Jonathan M. Hodgson, Nicola P. Bondonno

Research outputs 2022 to 2026

Studies examining the association between flavonoid intake and measures of insulin resistance and β-cell dysfunction, as markers of type 2 diabetes (T2DM) across the adult lifespan, may provide insights into how flavonoids influence T2DM risk. This study examined the cross-sectional associations between flavonoid intakes, from dietary sources other than tea, and biomarkers of glucose tolerance and insulin sensitivity in adults aged 25 years and older participating in the Australian diabetes, obesity and lifestyle (AusDiab) study. Additionally, longitudinal associations between non-tea flavonoid intakes and incident T2DM over 12 years were explored. Eligible participants (n = 7675) had no previous history of …


Brown Adipose Tissue (Bat) Activation And Its Potential Utilization As A Treatment Option For Obesity And Diabetes, Darcie B. Schneider Apr 2022

Brown Adipose Tissue (Bat) Activation And Its Potential Utilization As A Treatment Option For Obesity And Diabetes, Darcie B. Schneider

Student Publications

Within the human body, there are two types of adipose tissue: white adipose tissue (WAT) and brown adipose tissue (BAT). WAT is beneficial for insulation whereas BAT has thermogenic capacity. BAT activation increases energy consumption via heat generation. Increased energy expenditure is associated with improved glucose and lipid metabolism. Therefore, BAT activation research has primarily been aimed at its potential use in the treatment of obesity, diabetes, and other metabolic disorders. In this literature review, BAT's thermogenic mechanisms, techniques of activation, potential therapeutic targets, and future research topics are explored.


Standardizing Naturalistic Teaching Opportunities For Problem-Based Learning In Diabetes Education: A Quality Improvement Project, Austin Mccaslin Apr 2022

Standardizing Naturalistic Teaching Opportunities For Problem-Based Learning In Diabetes Education: A Quality Improvement Project, Austin Mccaslin

DNP Projects

Significance and Background:

Poor diabetes management is linked to serious long and short-term health complications. Despite this, medication adherence is a significant problem in adolescents with type 1 diabetes. Management is further complicated by low socioeconomic status, even when mitigated by free healthcare, highlighting health literacy as a culprit of disparities. Evidence shows that a common barrier for adolescents is proficiency in dose determination. Carbohydrate counting is an integral skill, necessary for attaining glycemic control. At a homecare agency serving adolescents with poorly controlled diabetes by providing oversight of medication administration and education, it was noted that patients continued to …


Longitudinal Relation Of Dietary Quality And Hemoglobin A1c In Youth And Young Adults With Diabetes, Hope Bercaw Apr 2022

Longitudinal Relation Of Dietary Quality And Hemoglobin A1c In Youth And Young Adults With Diabetes, Hope Bercaw

Theses and Dissertations

Background Hemoglobin A1c (HbA1c) is a clinical measure of glycemic control among people with diabetes and is associated with health outcomes such as cardiovascular disease. It is possible to decrease HbA1c by improving diet, but it is largely unknown which dietary components are most important in targeting glycemic control.

Objective This study aims to examine whether changes in diet quality across diabetes duration, assessed with the 2015-Healthy Eating Index (HEI), are associated with HbA1c in youth and young adults (YYA) with type 1 (T1D) and type 2 diabetes (T2D). Additionally, we aim to assess whether these relationships differ when dietary …


The Effects Of Physical Activity On Glycaemic Control In Children And Adolescents With Type 1 Diabetes Mellitus Participating In Diabetes Camps, Marcin Sikora, Anna Zwierzchowska, Marzena Jaworska, Magdalena Solich Talanda, Rafal Mikolajczyk, Aleksandra Zebrowska Mar 2022

The Effects Of Physical Activity On Glycaemic Control In Children And Adolescents With Type 1 Diabetes Mellitus Participating In Diabetes Camps, Marcin Sikora, Anna Zwierzchowska, Marzena Jaworska, Magdalena Solich Talanda, Rafal Mikolajczyk, Aleksandra Zebrowska

Baltic Journal of Health and Physical Activity

Background:‪Children with type 1 diabetes (T1D) are at high risk of having insufficient physical activity during school days and, thus, the importance of special program in promoting regular physical exercise has been largely emphasized. Therefore, this study examined the levels of physical activity and glycemia control in children with T1D, with particular focus on the relative contributions of regular physical education and physical activity program during the diabetes camp.Material and methods:‪Ninety-eight children suffering from T1D for 3.0 ±1.4 years free of diabetic complications participated in the study. Glycemia, insulin doses and diet were monitored, and physical activity was repeatedly measured …


The Impact Of Circuit Resistance Training On Serum Glucose, Insulin Resistance And Health Related Physical Fitness In Elderly Men With Type 2 Diabetes, Hamid Arazi, Roghayeh Gholizadeh, Amin Sohbatzadeh, Ehsan Eghbali Mar 2022

The Impact Of Circuit Resistance Training On Serum Glucose, Insulin Resistance And Health Related Physical Fitness In Elderly Men With Type 2 Diabetes, Hamid Arazi, Roghayeh Gholizadeh, Amin Sohbatzadeh, Ehsan Eghbali

Baltic Journal of Health and Physical Activity

Background: Obesity and decreased physical activity are the most important factors in the development of type 2 diabetes, which in recent decades has led to an increase in the number of people with this disease. The aim of this study was to investigate the impact of circuit resistance training (CRT) on serum glucose, insulin resistance and health related physical fitness in elderly men with type 2 diabetes. Material and methods: Twenty-two patients with type 2 diabetes (60.99 ±2.93 years) volunteered to participate in this study. They were divided randomly into two groups: training (n = 11) and control (n = …


Starvation Diets: The History And Moral Implications Of Prolonging The Lives Of Juvenile Diabetics Before The Discovery Of Insulin, Olivia Thompson Mar 2022

Starvation Diets: The History And Moral Implications Of Prolonging The Lives Of Juvenile Diabetics Before The Discovery Of Insulin, Olivia Thompson

Honors Program: Senior Projects (Public)

This study explores the state of diabetology before Frederick Banting’s discovery of insulin in 1921, when juvenile diabetes was a terminal diagnosis. The widespread misunderstanding of the disease at the hands of physicians and scientists culminated in improper treatments and erroneous anatomical literature about diabetes until the age of discovery in the late 19th and early 20th centuries. More extensively, I examine the controversial work of 20th-century physician Frederick Madison Allen, who attempted to prolong the lives of juvenile diabetics by subjecting them to a rigid starvation diet by way of experimental trials lasting from 1915 to 1922. This diet …


The Importance Of Nutrition In Oral Health In The General Population And Among Children And Adolescents, Emma Barnes Mar 2022

The Importance Of Nutrition In Oral Health In The General Population And Among Children And Adolescents, Emma Barnes

Honors Program: Senior Projects (Public)

Having good oral health is vital for the U.S. population. Although there have been improvements, too many suffer from dental caries and tooth loss. Providing education, dental procedures, and nutritional foods can help prevent these issues. Healthy choices include having a diet with adequate protein, vitamin A, vitamin C, and the vitamin B complex to support proper tissue development in the oral cavity.

Keeping good oral health is crucial for those suffering from diabetes mellitus. Studies show that doing this can help lower the patient's A1C, therefore helping with the management of blood glucose levels and potentially slowing the progression …


Impact Of A Dyadic Intervention On Family Supporter Involvement In Helping Adults Manage Type 2 Diabetes, Margaret F. Zupa, Aaron Lee, John D. Piette, Ranak Trivedi, Ada Youk, Michele Heisler, Ann Marie Rosland Mar 2022

Impact Of A Dyadic Intervention On Family Supporter Involvement In Helping Adults Manage Type 2 Diabetes, Margaret F. Zupa, Aaron Lee, John D. Piette, Ranak Trivedi, Ada Youk, Michele Heisler, Ann Marie Rosland

Faculty and Student Publications

Background: Family support for adults’ diabetes care is associated with improved self-management and outcomes, but healthcare providers lack structured ways to engage those supporters. Objective: Assess the impact of a patient-supporter diabetes management intervention on supporters’ engagement in patients’ diabetes care, support techniques, and caregiving experience. Design: Multivariate regression models examined between-group differences in support-related measures observed as part of a larger trial randomizing participants to a dyadic intervention versus usual care. Participants: A total of 239 adults with type 2 diabetes and either A1c >8% or systolic blood pressure >160mmHg enrolled with a family supporter. Intervention: Health coaches provided …


Evaluation Of A Hands-On Cooking Class And Its Effects On Self-Efficacy In Relation To Healthy Eating In Type 2 Diabetics, Codi A. Jenshak-Gorzinski Mar 2022

Evaluation Of A Hands-On Cooking Class And Its Effects On Self-Efficacy In Relation To Healthy Eating In Type 2 Diabetics, Codi A. Jenshak-Gorzinski

Doctor of Nursing Practice Scholarly Projects

The prevalence of Type 2 diabetes is alarming and poses a great threat to U.S. national health. Chronic diabetes can lead to serious conditions such as heart attack and stroke, and can result in premature mortality (World Health Organization, 2018). Diabetes can be prevented or treated by eating a healthy diet. Cooking classes are a potential way to improve American’s knowledge of nutritional principles and help them become confident that they have the capacity to eat a healthy diet. The purpose of this DNP project was to determine if participation in cooking classes enhanced self-efficacy as it pertains to healthy …


Implementing A Telephone Follow-Up Process For Patients With Poorly Controlled Type 2 Diabetes: A Nurse-Led Quality Improvement Project, Amber Gomes Mar 2022

Implementing A Telephone Follow-Up Process For Patients With Poorly Controlled Type 2 Diabetes: A Nurse-Led Quality Improvement Project, Amber Gomes

DNP Projects

Background: Diabetes is the seventh leading cause of death in America with approximately 1.5 million people diagnosed yearly (ADA, 2020). The current problem in the practice setting is the lack of follow-up of patients with hemoglobin A1c’s (HbA1c’s) 9% or greater. The current workflow utilizes care coordinators to perform patient outreach to patients with diabetes and a HbA1c of 9% or greater. This workflow is not structured and consists of randomly selecting a patient with a HbA1c 9% or greater and placing one phone call to them to provide education.

Purpose: The purpose of the project was to develop and …


Determining Vitamin D Status: A Comparison Between Diabetic And Non-Diabetic Women With Breast Cancer By Rp-Hplc, Santosh Gunasekaran, Suma M. Natraj, Prashanth Kumar M V Feb 2022

Determining Vitamin D Status: A Comparison Between Diabetic And Non-Diabetic Women With Breast Cancer By Rp-Hplc, Santosh Gunasekaran, Suma M. Natraj, Prashanth Kumar M V

Digital Journal of Clinical Medicine

Background:

Suboptimal levels of Vitamin D, remains a common problem worldwide and its prevalence is high in India, ranging from 70-100%. Several molecular mechanisms have been found about the effects of Vitamin D in modulating glycemic levels and its protective nature in the development of breast cancer. Breast cancer in India is a common problem and studies regarding its association with Vitamin D levels among diabetics remain inconclusive. This study aims to find the association between Vitamin D status and breast cancer in diabetic and non-diabetic women.

Materials and methods:

25 hydroxy vitamin D levels were estimated by RP-HPLC. A …


'Analogy-Based Comprehensive Diabetes Education' (Abcde) Improves Glycemic Control Of Diabetic Patients In An Underserved Population: Results Of A Retrospective Chart Analysis, Rajagopal V Sekhar Feb 2022

'Analogy-Based Comprehensive Diabetes Education' (Abcde) Improves Glycemic Control Of Diabetic Patients In An Underserved Population: Results Of A Retrospective Chart Analysis, Rajagopal V Sekhar

Faculty, Staff and Students Publications

Diabetes is the leading global cause for blindness, kidney failure and amputations. Preventing these complications requires optimal glycemic control, and it is imperative that diabetic patients understand the fundamental concepts of diabetes care. Although patients attend formal diabetes education classes, many do not comprehend basic concepts of diabetes, and are often noncompliant with diet, exercise and medications. A novel approach termed 'analogy-based comprehensive diabetes education' (ABCDE) was developed to educate HIV-patients with diabetes about basic concepts of diabetes care. The object of this manuscript is to report the results of a retrospective chart review on the impact of ABCDE on …


Biphasic Glucose Curve Morphology Reflects Better Glucose Tolerance And Substrate Utilization, Jehu Narh Apaflo, Joshua Labadah, Ali Mossayebi, Victoria Rocha, Sudip Bajpeyi Feb 2022

Biphasic Glucose Curve Morphology Reflects Better Glucose Tolerance And Substrate Utilization, Jehu Narh Apaflo, Joshua Labadah, Ali Mossayebi, Victoria Rocha, Sudip Bajpeyi

International Journal of Exercise Science: Conference Proceedings

The shape of glucose curve during an oral glucose tolerance test is a plausible risk factor for insulin resistance and other metabolic disorders and could be a potential biomarker for predicting risk for developing diabetes. PURPOSE: This study aimed to compare the glucose tolerance and substrate utilization between monophasic and biphasic glucose curve morphologies. METHODS: A total of 50 subjects (33/17 male/female; Age: 27 ± 7.74 years; BMI: 27.7 ± 4.97 kg/m2) without diabetes were tested for a two-hour oral glucose tolerance after ingesting 75g of glucose drink. Blood glucose levels were measured at time points …


Lifestyle Factors Affecting Android Fat In Hispanic Residents Of The Rgv, Alexandro Rodriguez, Ryan D. Russell, Smaran Marupudi, Gabriel Figueroa, Jaime Rodriguez, Saraswathy Nair, Jimmy Gonzalez, Yu Lun Tai Feb 2022

Lifestyle Factors Affecting Android Fat In Hispanic Residents Of The Rgv, Alexandro Rodriguez, Ryan D. Russell, Smaran Marupudi, Gabriel Figueroa, Jaime Rodriguez, Saraswathy Nair, Jimmy Gonzalez, Yu Lun Tai

International Journal of Exercise Science: Conference Proceedings

ABSTRACT

Approximately 79% of the Hispanic population in the Rio Grande Valley (HPRGV) are overweight or obese. As such, this population also have ~3x the type 2 diabetes (T2D) rates than the US average. Distribution of adipose tissue, affected largely by genetics and lifestyle (diet and physical activity, has been identified as a key-marker for T2D risk among apparently healthy individuals. However, the relationship of lifestyle factors such as diet and physical activity on android fat in healthy young Hispanics of the RGV has not been completely explored. Purpose: The purpose of this study was to determine whether there is …


Metabolic Flexibility In Healthy Hispanics In The Rio Grande Valley With And Without A Family History Of Type 2 Diabetes, Jaime Rodriguez, Ryan D. Russell, Gabriel A. Figueroa, Alexandro Rodriguez, Smaran Marupudi, Yu Lun Tai, Sara Swathy, Jimmy Gonzales Feb 2022

Metabolic Flexibility In Healthy Hispanics In The Rio Grande Valley With And Without A Family History Of Type 2 Diabetes, Jaime Rodriguez, Ryan D. Russell, Gabriel A. Figueroa, Alexandro Rodriguez, Smaran Marupudi, Yu Lun Tai, Sara Swathy, Jimmy Gonzales

International Journal of Exercise Science: Conference Proceedings

ABSTRACT Type 2 Diabetes (T2D) has several comorbidities such as cardiovascular disease, elevated lipid profile, microvascular complications, and impaired metabolic flexibility (MF: the ability to switch substrate use upon stimulation). Further, healthy Caucasians with a family history of T2D (FH+) have impaired MF similar to T2D, suggesting impaired MF could be an early-detection tool to identify at-risk populations. Hispanics of the Rio Grande Valley have ~3x the T2D rates as the US average, and have ~79% of the people in this region are either overweight or obese. However, patterns of MF in this population have not been addressed. Purpose: The …


Body Mass Index (Bmi): A Screening Tool Analysis, Deepesh Khanna, Cadynce Peltzer, Payal Kahar, Mayur S. Parmar Feb 2022

Body Mass Index (Bmi): A Screening Tool Analysis, Deepesh Khanna, Cadynce Peltzer, Payal Kahar, Mayur S. Parmar

HPD Articles

Body mass index (BMI), a measurement based on a person's height and weight, allows the classification of individuals into categories such as obese or overweight. With these classifications, we can assess risk for hypertension, diabetes, cancer, hypercholesterolemia, and other chronic diseases. Furthermore, childhood BMI serves as a prediction method for health and disease later in life. Along with BMI, researchers also study waist circumference and waist-to-hip ratio in correlation with the above-mentioned chronic illnesses. This brief review explores the associations between body mass index, waist circumference, and the waist-hip ratio as measurements and their capability as predictors for persistent conditions …


Exercise/Physical Activity In Individuals With Type 2 Diabetes: A Consensus Statement From The American College Of Sports Medicine, Jill A. Kanaley, Sheri R. Colberg, Matthew H. Corcoran, Steven K. Malin, Nancy R. Rodriguez, Carlos J. Crespo, John P. Kirwan, Juleen R. Zierath Feb 2022

Exercise/Physical Activity In Individuals With Type 2 Diabetes: A Consensus Statement From The American College Of Sports Medicine, Jill A. Kanaley, Sheri R. Colberg, Matthew H. Corcoran, Steven K. Malin, Nancy R. Rodriguez, Carlos J. Crespo, John P. Kirwan, Juleen R. Zierath

OHSU-PSU School of Public Health Faculty Publications and Presentations

This consensus statement is an update of the 2010 American College of Sports Medicine position stand on exercise and type 2 diabetes. Since then, a substantial amount of research on select topics in exercise in individuals of various ages with type 2 diabetes has been published while diabetes prevalence has continued to expand worldwide. This consensus statement provides a brief summary of the current evidence and extends and updates the prior recommendations. The document has been expanded to include physical activity, a broader, more comprehensive definition of human movement than planned exercise, and reducing sedentary time. Various types of physical …


Clinical Characteristics Of Peripheral Neuropathy In Kenyan Patients With Hiv Infection Compared With Patients With Concurrent Hiv Infection And Diabetes Mellitus, Pascal Kuka, Jasmit Shah, Uazman Alam, Reena Shah, Dilraj Sokhi Feb 2022

Clinical Characteristics Of Peripheral Neuropathy In Kenyan Patients With Hiv Infection Compared With Patients With Concurrent Hiv Infection And Diabetes Mellitus, Pascal Kuka, Jasmit Shah, Uazman Alam, Reena Shah, Dilraj Sokhi

Internal Medicine, East Africa

Introduction: Persons living with human immunodeficiency virus (HIV) are living longer and at risk of non-communicable diseases, including diabetes mellitus (DM). Both HIV and DM place patients at risk of peripheral neuropathy (PN). Our aim was to demonstrate the prevalence and characteristics of PN in our population of patients with HIV infection compared with concomitant HIV and DM.

Methods: A prospective cross-sectional study was performed at the Aga Khan Hospital in Nairobi, Kenya. Data were collected on demographics and characteristics of DM and HIV. Symptoms and signs of PN were evaluated by Neuropathy Symptom Score, Neuropathy Disability Score, …


Ghrelin And Leptin And Their Relations With Insulin Resistance In Diabetes Mellitus Type 2 Patients, Chinar Hameed Sadiq, Ridha Hassan Hussein, Ismail Mustafa Maulood Feb 2022

Ghrelin And Leptin And Their Relations With Insulin Resistance In Diabetes Mellitus Type 2 Patients, Chinar Hameed Sadiq, Ridha Hassan Hussein, Ismail Mustafa Maulood

Baghdad Science Journal

Ghrelin and leptin are hunger hormones related to type 2 diabetes mellitus (T2DM), and the pathogenesis of T2DM is the abnormality in insulin secretion and insulin resistance (IR). The aim of this study is to evaluate ghrelin and leptin concentrations in blood and to specify the relationship of these hormones as dependent variables with some biochemical and clinical measurements in T2DM patients. In this study, forty one T2DM and forty three non-diabetes mellitus (non-DM) subjects, aged between 40-60 years and with normal weight, were enrolled. Fasting serum ghrelin and leptin were estimated by enzyme-linked immunosorbent assay (ELISA). In our results …


A Narrative Review Of The Evidence For Variations In Serum 25-Hydroxyvitamin D Concentration Thresholds For Optimal Health, William B. Grant, Fatme Al Anouti, Barbara J. Boucher, Erdinç Dursun, Duygu Gezen-Ak, Edward B. Jude, Tatiana Karonova, Pawel Pludowski Feb 2022

A Narrative Review Of The Evidence For Variations In Serum 25-Hydroxyvitamin D Concentration Thresholds For Optimal Health, William B. Grant, Fatme Al Anouti, Barbara J. Boucher, Erdinç Dursun, Duygu Gezen-Ak, Edward B. Jude, Tatiana Karonova, Pawel Pludowski

All Works

Vitamin D3 has many important health benefits. Unfortunately, these benefits are not widely known among health care personnel and the general public. As a result, most of the world’s population has serum 25-hydroxyvitamin D (25(OH)D) concentrations far below optimal values. This narrative review examines the evidence for the major causes of death including cardiovascular disease, hypertension, cancer, type 2 diabetes mellitus, and COVID-19 with regard to sub-optimal 25(OH)D concentrations. Evidence for the beneficial effects comes from a variety of approaches including ecological and observational studies, studies of mechanisms, and Mendelian randomization studies. Although randomized controlled trials (RCTs) are generally considered …


The Urgency Of Sugar Sweetened Beverages Excise Policy: A Literature Study For Implementation In Indonesia, Mohamad Luhur Hambali Jan 2022

The Urgency Of Sugar Sweetened Beverages Excise Policy: A Literature Study For Implementation In Indonesia, Mohamad Luhur Hambali

BISNIS & BIROKRASI: Jurnal Ilmu Administrasi dan Organisasi

Diabetes diseases should become an alert for all people around the world, including Indonesia. Being one of the ten diseases that are classified as dangerous diseases, diabetes is estimated to infect 700 million people by 2045. Strategic steps must be taken by the Indonesian government, one of them is through the implementation of fiscal policy on the collection of Sugar Sweetened Beverages (SSB) Excise. Using secondary sources data through literature review by looking for information about countries that have implemented the SSB Excise, this paper goals are to analyze the urgency of implementing a SSB Excise that can be applied …


Diabetic Care Pathway, Shalini Bansal, Kayla Brockmeyer, Nick Kieran Jan 2022

Diabetic Care Pathway, Shalini Bansal, Kayla Brockmeyer, Nick Kieran

Physician Executive Leadership-Plus (PEL-Plus)

Presentation Outline

  • The Impact of Diabetes
  • Problem Statement
  • Solution
  • Looking to the Future


Sex Differences In The Association Of Sibship Size And Position In Sibship With Lipid Profile During Adolescence: A Cross-Sectional Study, Ali H. Ziyab, Mohammad Almari, Anwar Mohammad, Abdullah Al-Taiar, Wilfried Karmaus Jan 2022

Sex Differences In The Association Of Sibship Size And Position In Sibship With Lipid Profile During Adolescence: A Cross-Sectional Study, Ali H. Ziyab, Mohammad Almari, Anwar Mohammad, Abdullah Al-Taiar, Wilfried Karmaus

Community & Environmental Health Faculty Publications

Background. Epidemiologic studies have reported associations of sibship size and position of the child in the sibship with multiple health outcomes, including adiposity and diabetes. However, little is known about sibling effects on lipids. Hence, this study sought to evaluate associations of the number of total, older, and younger siblings with lipid profile among adolescents. Methods. In a cross-sectional study among high school students aged 14 to 19 years, lipid levels were measured in capillary blood. Parents reported the number of siblings (total, older, and younger). Geometric means of lipids were calculated, and linear regression was used to estimate the …


Small G- Protein Regulators Of Islet Beta Cell Function, Suhadinie Sameera Gamage Jan 2022

Small G- Protein Regulators Of Islet Beta Cell Function, Suhadinie Sameera Gamage

Wayne State University Dissertations

Defects in insulin secretion from pancreatic islet beta- cells leads to long term complications such as type 2 diabetes mellitus. The mechanism and regulation of glucose stimulated insulin secretion (GSIS) as well as factors contributing to pancreatic islet beta-cell demise are yet poorly understood. Previous work from our laboratory demonstrated that Ras-related C3 botulinum toxin substrate 1 (Rac1), a small G- protein is involved in GSIS as well as in culminating dysfunction under metabolic stress. Cycling of Rac1 between its inactive and active form is considered a vital event in glucose stimulated insulin secretion. This conversion is made possible by …