Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

COVID-19

Discipline
Institution
Publication Year
Publication
Publication Type
File Type

Articles 151 - 180 of 3471

Full-Text Articles in Entire DC Network

Characterization Of Sars-Cov-2 Replication And Transcription Complexes Via Structural And Evolutionary Approaches, Amelie Ghirardo, Ben Shabatian, Avishai Aghelian, Kyle Tau, Eleonora Gianti May 2025

Characterization Of Sars-Cov-2 Replication And Transcription Complexes Via Structural And Evolutionary Approaches, Amelie Ghirardo, Ben Shabatian, Avishai Aghelian, Kyle Tau, Eleonora Gianti

Undergraduate Research

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused around 700M cases and over 7M COVID-19-related deaths recorded worldwide (World Health Organization, March 2025). Aiming to effectively combat this and other disease-causing Coronaviruses (CoV), unprecedented research efforts led to the development of new vaccines and antiviral therapies. Due to emergence of variants of concern (VOCs) with increased transmissibility, immune evasion from vaccination, and potential to resist the available treatments, SARS-CoV-2 continues to represent a major threat to global health. Hence, there is a pressing need to discover new antivirals with broad-spectrum efficacy against multiple SARS-CoV-2 variants and related CoVs. This project …


Seeing Resilience Through Experience: Teachers' Resilience Experiences Post Covid-19 Pandemic, Yashica Dudley May 2025

Seeing Resilience Through Experience: Teachers' Resilience Experiences Post Covid-19 Pandemic, Yashica Dudley

Doctoral Dissertations and Projects

The purpose of this phenomenological was to describe the post-COVID-19 resilience experiences of 6th to 12th grade schoolteachers at Hope County Public School (HCPS). The theory that guided this study is the differing pathways to resiliency theory, as it was used to describe teachers’ resilience experiences regarding the outlook on work, self-efficacy, and coping responses. The central research question was, “What are the post-COVID-19 resilience experiences of 6th to 12th grade schoolteachers at the HCPS in the classroom?” Participants included 10-15 6th to 12th grade schoolteachers who taught before, during, and post the COVID-19 pandemic. The data was collected through …


Impact Of Nursing Home Staff Hours And Administrator Turnover On Quality Of Care Post-Covid-19 Pandemic In Texas, Kendra King May 2025

Impact Of Nursing Home Staff Hours And Administrator Turnover On Quality Of Care Post-Covid-19 Pandemic In Texas, Kendra King

Walden Dissertations and Doctoral Studies

Nursing facilities experienced heightened unfavorable outcomes related to quality of care and staffing patterns during the COVID-19 pandemic. The purpose of this quantitative, quasi-experimental, retrospective study was to determine if there was a relationship between nursing home administrator turnover, total nurse staffing (i.e., LPN, RN, and nurse aides) hours per resident per day, and the quality of care as measured by the Long Stay Quality Measure (LSQM) rating in Texas after the COVID-19 pandemic in 2023. The Donabedian model, using the elements of structure, process, and outcomes, served as the theoretical framework for this study. Structure was represented by the …


Turning Analysis Into Action: Opportunities And Challenges In Implementing Wastewater Science For Public Health Decision-Making, Anna Gitter, Valeria Ruvalcaba, Katelyn Clark, Theresa Tran Carapucci, Fuqing Wu, Blake M Hanson, Jennifer Deegan, John Balliew, Eric Boerwinkle, Anthony W Maresso, Kristina D Mena May 2025

Turning Analysis Into Action: Opportunities And Challenges In Implementing Wastewater Science For Public Health Decision-Making, Anna Gitter, Valeria Ruvalcaba, Katelyn Clark, Theresa Tran Carapucci, Fuqing Wu, Blake M Hanson, Jennifer Deegan, John Balliew, Eric Boerwinkle, Anthony W Maresso, Kristina D Mena

Faculty, Staff and Students Publications

In the 5 years since the emergence of the COVID-19 pandemic, the field of wastewater-based epidemiology (WBE) has dramatically expanded with programs implemented across the globe to monitor for SARS-CoV-2 and other viruses of public health concern. However, the best way to use wastewater surveillance data and inform local communities of the utility of wastewater science remains limited and sporadically discussed. Specifically, there is vague guidance regarding interpreting varying levels of viral loads in wastewater for public health significance. While collaborative efforts are key to implementing these community-specific wastewater surveillance programs, effectively using the data for public health decision-making still …


Leading Through Crisis: San Diego County Schools' Response To The Social Emotional Needs Of All Students, Johana Bielma May 2025

Leading Through Crisis: San Diego County Schools' Response To The Social Emotional Needs Of All Students, Johana Bielma

Dissertations

The COVID-19 pandemic led to unprecedented school closures, forcing administrators to take decisive action to radically change the educational system. The imperative to switch to remote learning transformed the dynamics of teaching and learning, leading to both immediate and long-term academic and social emotional consequences for all stakeholders. When schools reopened, administrators faced the challenge of reintegrating students into in-person learning while addressing the pandemic’s lasting effects on academics, mental health, and school safety. While academic regression was evident, the extent of students’ emotional struggles was less anticipated. Many students exhibited increased irritability and mental health issues such as depression …


Covid-19 And Related Adverse Neurological Complications, Hannah A. Wasson May 2025

Covid-19 And Related Adverse Neurological Complications, Hannah A. Wasson

Honors Thesis

Abstract

The COVID-19 pandemic changed the world drastically, and its impact was monumental. COVID-19 or SARS-CoV-2, or severe acute respiratory syndrome, was the virus responsible for causing such mayhem. This contagious virus can enter the body via different routes, live on surfaces for hours, and be transmitted through the air, increasing infection risk. Once it enters the body, it can trick the body into replicating the virus. From this reaction within the body, signs and symptoms follow. While the name indicates a respiratory illness, the virus can inflict injury on other parts of the body. Due to the organ systems …


Covid-19 Infection History As A Risk Factor For Early Pregnancy Loss: Results From The Electronic Health Record-Based Southeast Texas Covid And Pregnancy Cohort Study, Micaela N Sandoval, Michelle R Klawans, Mackinsey A Bach, Jennifer Mikhail, Edward A Graviss, Tru Cao, Jacqueline G Parchem, Junaid Husain, Eric Boerwinkle May 2025

Covid-19 Infection History As A Risk Factor For Early Pregnancy Loss: Results From The Electronic Health Record-Based Southeast Texas Covid And Pregnancy Cohort Study, Micaela N Sandoval, Michelle R Klawans, Mackinsey A Bach, Jennifer Mikhail, Edward A Graviss, Tru Cao, Jacqueline G Parchem, Junaid Husain, Eric Boerwinkle

Faculty, Staff and Student Publications

Background: The effects of SARS-CoV-2 infection before or during pregnancy on pregnancy outcomes are still largely unknown. We hypothesized that COVID-19 in early pregnancy is a risk factor for adverse pregnancy outcomes, particularly miscarriage.

Methods: We examined the relationship between COVID-19 and adverse pregnancy outcomes, including spontaneous abortion, ectopic pregnancy, and preterm delivery in a large, retrospective, electronic health record (EHR)-based cohort, from 2019 to 2023. Generalized estimating equation modeling was performed to identify risk factors for adverse pregnancy outcomes. Study exposures included COVID-19 before pregnancy, COVID-19 during pregnancy, age, race/ethnicity, comorbidity burden, and neighborhood-level social vulnerability.

Results: In the …


Lived Experiences Of Icu Nurses Caring For Critically Ill Patients Infected With Covid-19: A Phenomenological Study In Thailand, Charuedee Putruttanamaneekun, Yaowarat Matchim, Thitiporn Pathomjaruwat, Thanyarat Boontoi, Itsari Srisupha-Olarn, Sukanya Thongbupa, Borwarnluck Thongthawee, Parinya Raetong May 2025

Lived Experiences Of Icu Nurses Caring For Critically Ill Patients Infected With Covid-19: A Phenomenological Study In Thailand, Charuedee Putruttanamaneekun, Yaowarat Matchim, Thitiporn Pathomjaruwat, Thanyarat Boontoi, Itsari Srisupha-Olarn, Sukanya Thongbupa, Borwarnluck Thongthawee, Parinya Raetong

Journal of Health Research

Background: COVID-19 is an emerging disease that caused infections and a pandemic worldwide. Intensive care unit (ICU) nurses played an important role in providing care for critically ill patients. Their experiences during the pandemic in Thailand were not well documented. This study explored the lived experiences of ICU nurses caring for critically ill patients infected with COVID-19 in Thailand.

Methods: We conducted a qualitative, phenomenological study guided by Gadamer’s philosophical hermeneutics. Data were collected between December 2021 and March 2023 among fifteen ICU nurses at a university hospital. The partcipants drew pictures reflecting their experiences; they participated in in-depth interviews …


Parental Vaccine Hesitancy And The Decision To Vaccinate Children Against Covid-19, Jessica Mckee May 2025

Parental Vaccine Hesitancy And The Decision To Vaccinate Children Against Covid-19, Jessica Mckee

Walden Dissertations and Doctoral Studies

While there is a significant body of literature regarding vaccine hesitancy, there is a gap in the literature on its impact to parents’ decisions to vaccinate their children against a pandemic pathogen. The purpose of this study was to examine the relationship between parental vaccine hesitancy, measured using the health belief model (HBM) theoretical framework constructs of the Vaccine Hesitancy Scale (VHS; the degree to which an individual trusts in vaccine efficacy, safety, the reliability and trustworthiness of vaccine programs, community impact, perceived risks, and the importance of childhood vaccinations), and parents’ decision to vaccinate their children against COVID-19 with …


Covid 19 And Its Widespread Effects On Autoimmune Disease, Jessica Ngo, Michelle Jankowski, Matthew Sims, Dwayne Baxa May 2025

Covid 19 And Its Widespread Effects On Autoimmune Disease, Jessica Ngo, Michelle Jankowski, Matthew Sims, Dwayne Baxa

Conference Presentation Abstracts

COVID-19 has disproportionately affected racial and ethnic minority groups and immunocompromised groups, including those with autoimmune diseases. Studies have shown that African American, Hispanic, and Asian American individuals have higher risk of COVID-19 positivity and ICU admissions. SARS-CoV-2 shares numerous similarities with autoimmune diseases in its symptomology and ability to dysregulate the immune response. This study seeks to investigate differences in COVID-related outcomes between patients with autoimmune diseases and the general population. Methods A multi-center retrospective study was conducted with data from the EPIC database at Corewell Health System in Michigan from December 2019 to November 2021. Variables collected included …


An Intranasal Subunit Vaccine Induces Protective Systemic And Mucosal Antibody Immunity Against Respiratory Viruses In Mouse Models., Aina Karen Anthi, Anette Kolderup, Eline Benno Vaage, Malin Bern, Sopisa Benjakul, Elias Tjärnhage, Fulgencio Ruso-Julve, Kjell-Rune Jensen, Heidrun Elisabeth Lode, Marina Vaysburd, Jeannette Nilsen, Marie Leangen Herigstad, Siri Aastedatter Sakya, Lisa Tietze, Diego Pilati, Mari Nyquist-Andersen, Mirjam Dürkoop, Torleif Tollefsrud Gjølberg, Linghang Peng, Stian Foss, Morten C Moe, Benjamin E. Low, Michael V. Wiles, David Nemazee, Frode L Jahnsen, John Torgils Vaage, Kenneth A Howard, Inger Sandlie, Leo C James, Gunnveig Grødeland, Fridtjof Lund-Johansen, Jan Terje Andersen May 2025

An Intranasal Subunit Vaccine Induces Protective Systemic And Mucosal Antibody Immunity Against Respiratory Viruses In Mouse Models., Aina Karen Anthi, Anette Kolderup, Eline Benno Vaage, Malin Bern, Sopisa Benjakul, Elias Tjärnhage, Fulgencio Ruso-Julve, Kjell-Rune Jensen, Heidrun Elisabeth Lode, Marina Vaysburd, Jeannette Nilsen, Marie Leangen Herigstad, Siri Aastedatter Sakya, Lisa Tietze, Diego Pilati, Mari Nyquist-Andersen, Mirjam Dürkoop, Torleif Tollefsrud Gjølberg, Linghang Peng, Stian Foss, Morten C Moe, Benjamin E. Low, Michael V. Wiles, David Nemazee, Frode L Jahnsen, John Torgils Vaage, Kenneth A Howard, Inger Sandlie, Leo C James, Gunnveig Grødeland, Fridtjof Lund-Johansen, Jan Terje Andersen

Faculty Research 2025

Although vaccines are usually given intramuscularly, the intranasal delivery route may lead to better mucosal protection and limit the spread of respiratory virus while easing administration and improving vaccine acceptance. The challenge, however, is to achieve delivery across the selective epithelial cell barrier. Here we report on a subunit vaccine platform, in which the antigen is genetically fused to albumin to facilitate FcRn-mediated transport across the mucosal barrier in the presence of adjuvant. Intranasal delivery in conventional and transgenic mouse models induces both systemic and mucosal antigen-specific antibody responses that protect against challenge with SARS-CoV-2 or influenza A. When benchmarked …


Administrative Law And The Pandemic, Gillian E. Metzger May 2025

Administrative Law And The Pandemic, Gillian E. Metzger

Faculty Scholarship

American administrative law’s relationship to change is, as they say, compli­cated. On the one hand, continual evolution has been an endemic feature of American administrative law. Doctrines such as Chevron deference to agency statutory interpretations were born, grew, and declined in just the period from the 1980s to today. On the other, the United States (US) Supreme Court regularly rejects such common law development in administrative law as illegitimate and insists that federal judges must adhere to the original terms of the 1946 Administrative Procedure Act (APA) and other statutes, unless the Constitution requires otherwise. And to this day scholars …


School Counselors’ Lived Experiences During The Covid-19 Pandemic, Katie M. Guzman Dunn May 2025

School Counselors’ Lived Experiences During The Covid-19 Pandemic, Katie M. Guzman Dunn

Doctoral Dissertations and Projects

The purpose of this phenomenological study was to understand how school counselor perceptions of their roles may have been permanently impacted by the COVID-19 pandemic. Bronfenbrenner’s (1979) Ecological Systems Theory, which relates to the interactions of an individual and the environment around them, guided the study. The study’s central research was: What are public school counselors’ lived experiences regarding their role perception during the COVID-19 pandemic? Data was collected through virtual semi-structured interviews and photo elicitation with 10 school counselors who were members of the Kentucky School Counselor Association. The data collected from the interviews was analyzed using bracketing to …


The Burden Of Care: A Phenomenological Inquiry Into The Lived Experiences Of Homeless Shelter Administrators Leading Through The Pandemic And Lasting Implications On Program Operations, Marie Adele Wilson May 2025

The Burden Of Care: A Phenomenological Inquiry Into The Lived Experiences Of Homeless Shelter Administrators Leading Through The Pandemic And Lasting Implications On Program Operations, Marie Adele Wilson

Doctoral Dissertations and Projects

The theories guiding this study are Maslow's Hierarchy of Needs, conflict theory, and complex systems theory, which explain the relationship between the theory and resource limitations and acquisition, systems, and nature of acquiring human needs. The purpose of this phenomenological study is to describe homeless shelter administrators'/directors' experiences delivering services during the COVID-19 pandemic on the Eastern Coast of the United States and Texas. It further seeks to unravel how the pandemic informed the delivery of services and program administration related to homeless shelters and its impacts. The research questions sought to understand the impact of COVID-19 on delivering services …


Contagions Of Doubt: Denialism And The Spread Of Medical Conspiracy Theories, Haley Boom May 2025

Contagions Of Doubt: Denialism And The Spread Of Medical Conspiracy Theories, Haley Boom

Anthropology

Denialism and conspiratorial thinking have long shaped public perceptions of science and medicine, but the COVID-19 pandemic exposed how rapidly these forces can evolve and spread in a digital age. This thesis examines the historical roots, psychological foundations, and modern amplification of medical conspiracy theories, with a particular focus on vaccine skepticism and COVID-19-related misinformation. As a literature review, it synthesizes existing interdisciplinary research from psychology, public health, and communication studies to explore how medical conspiracy beliefs emerge from complex interactions between cognitive biases, emotional needs, mistrust in institutions, and evolving media environments. The rise of social media, political polarization, …


Evaluating The Test-Negative Design For Covid-19 Vaccine Effectiveness Using Randomized Trial Data: A Secondary Cross-Protocol Analysis Of 5 Randomized Clinical Trials, Leah I B Andrews, M Elizabeth Halloran, Kathleen M Neuzil, Lars Van Der Laan, Yunda Huang, Jessica Andriesen, Mayur Patel, Leigh H Fisher, Holly Janes, Nadine Rouphael, Stephen R Walsh, Deborah A Theodore, Hong-Van Tieu, Magdalena Sobieszczyk, Hana M El Sahly, Lindsey R Baden, Ann R Falsey, Thomas B Campbell, Colleen F Kelley, Catherine Mary Healy, Lilly Immergluck, Benjamin Luft, Ian Hirsch, Guy De Bruyn, Carla Truyers, Frances Priddy, Kelsey M Sumner, Brendan Flannery, Dean Follmann, Peter B Gilbert, Covid-19 Prevention Network (Covpn) May 2025

Evaluating The Test-Negative Design For Covid-19 Vaccine Effectiveness Using Randomized Trial Data: A Secondary Cross-Protocol Analysis Of 5 Randomized Clinical Trials, Leah I B Andrews, M Elizabeth Halloran, Kathleen M Neuzil, Lars Van Der Laan, Yunda Huang, Jessica Andriesen, Mayur Patel, Leigh H Fisher, Holly Janes, Nadine Rouphael, Stephen R Walsh, Deborah A Theodore, Hong-Van Tieu, Magdalena Sobieszczyk, Hana M El Sahly, Lindsey R Baden, Ann R Falsey, Thomas B Campbell, Colleen F Kelley, Catherine Mary Healy, Lilly Immergluck, Benjamin Luft, Ian Hirsch, Guy De Bruyn, Carla Truyers, Frances Priddy, Kelsey M Sumner, Brendan Flannery, Dean Follmann, Peter B Gilbert, Covid-19 Prevention Network (Covpn)

Faculty, Staff and Students Publications

Importance: The test-negative design (TND) has been widely used to assess postmarketing COVID-19 vaccine effectiveness but requires further evaluation for this application.

Objective: To determine whether the TND reliably evaluates vaccine effectiveness against symptomatic COVID-19 using placebo-controlled vaccine efficacy randomized clinical trials (RCTs).

Design, setting, and participants: This secondary cross-protocol analysis constructed TND study datasets from study sites in 16 countries across 5 continents using the blinded phase cohorts of 5 harmonized phase 3 COVID-19 Prevention Network RCTs: COVE (Coronavirus Vaccine Efficacy and Safety), AZD1222, ENSEMBLE, PREVENT-19 (Prefusion Protein Subunit Vaccine Efficacy Novavax Trial COVID-19), and VAT00008. Participants included adults …


From Unrealistic To Functional Optimism In Illness Perception: A Psychometric Comparison Across 10 Countries, Elisa Kern De Castro, Oscar Lecuona, Maria João Figueiras, Cristina Quiñones, Kamlesh Singh, Shoshana Shiloh, Michaela Schippers, Ana Kinkead, Raquel Rodríguez-Carvajal Apr 2025

From Unrealistic To Functional Optimism In Illness Perception: A Psychometric Comparison Across 10 Countries, Elisa Kern De Castro, Oscar Lecuona, Maria João Figueiras, Cristina Quiñones, Kamlesh Singh, Shoshana Shiloh, Michaela Schippers, Ana Kinkead, Raquel Rodríguez-Carvajal

All Works

People's perceptions of illness and its risks influence health behaviors, including risk management and precautionary measures. Illness perception often involves unrealistic optimism, reducing infection risk perception. However, crises disrupt self-regulation and optimism due to uncontrollable situations. This study examines optimism's link to risk and illness perception during the first COVID-19 wave in 10 countries, with 7254 participants (48.1% women, mean age = 40, SD = 14.8). We used Bayesian structural equation modeling for psychometric stability and one-way ANOVAs for country comparisons. Multiple regression analyses examined the impact of optimism and demographic variables on illness perception. Significant cross-country variations emerged in …


Impact Of Pandemic-Driven Parental Fear On Childhood Immunization Rates: Examining Attitudes Toward Vaccination During Crisis Periods In Türkiye, Özüm Erkin, İlknur Göl Apr 2025

Impact Of Pandemic-Driven Parental Fear On Childhood Immunization Rates: Examining Attitudes Toward Vaccination During Crisis Periods In Türkiye, Özüm Erkin, İlknur Göl

Makara Journal of Health Research

Background: This study aimed to investigate the effect of parents’ fear of coronavirus on their attitudes towards the vaccination of their children.

Methods: The study was conducted with 2,350 parents who were selected by using the snowball sampling method. The questionnaire included a personal information form, the Public Attitude towards Vaccination Scale – Health Belief Model, and the Fear of COVID-19 Scale.

Results: The scores of the study group from the sub-dimensions of the Public Attitude towards Vaccination Scale Health Belief Model were as follows: 17.39 ± 2.92 perceived susceptibility, 16.74 ± 3.19 perceived severity, 21.10 ± …


Incalculable Harm: Analyzing The Impact Of The Covid-19 Pandemic On Immigration Detention In Canada, Efrat Arbel, Molly Joeck Apr 2025

Incalculable Harm: Analyzing The Impact Of The Covid-19 Pandemic On Immigration Detention In Canada, Efrat Arbel, Molly Joeck

All Faculty Publications

This paper reflects on the impact of the COVID-19 pandemic on immigration detention in Canada. Drawing on research spanning 2020 to 2022, we analyze how the pandemic impacted rates of detention, conditions of detention, and other related issues. Data released by the Canada Border Services Agency shows that despite an initial decrease in absolute numbers, Canada detained people at a higher rate after the onset of the pandemic than it did prior. Canada also held people for longer periods of time and relied more heavily on jails than dedicated Immigration Holding Centres. Conditions of confinement deteriorated significantly across all detention …


Determining The Mental Health Climate Of The Ministers Of Christian Churches In Metro Vancouver After The Reopening Of The Churches Since Covid-19 Closure, Lap Cho Chan Apr 2025

Determining The Mental Health Climate Of The Ministers Of Christian Churches In Metro Vancouver After The Reopening Of The Churches Since Covid-19 Closure, Lap Cho Chan

Doctoral Dissertations and Projects

The burnout of ministers is real. Ministers are human, just like everyone else in the world. Too many people (such as church officials and leaders) underestimate the adverse effects of burned-out ministers in their churches. The pandemic had a huge impact on all the churches in Metro Vancouver, Canada. Ministers experienced exceptionally high stress and anxiety after the reopening of churches after the COVID-19 closure. Thus, the purpose of this DMIN action research project is to use the Maslach Burnout Inventory (MBI), surveys, questionnaires, and interviews to research, qualify, and quantify the mental health climate of ministers in Metro Vancouver. …


The Perceived Impact Of Covid-19 On The Grief Process Of African American Adults, Tondra Crumpler Mclaurin Apr 2025

The Perceived Impact Of Covid-19 On The Grief Process Of African American Adults, Tondra Crumpler Mclaurin

Doctoral Dissertations and Projects

The COVID-19 pandemic disproportionately affected African Americans in the areas of infections, hospitalizations, and deaths. Research studies have historically focused primarily on the grief experiences of European Americans. The purpose of this phenomenological qualitative study is to understand the impact of the COVID-19 pandemic on the bereavement experience of African American adults. The theoretical frameworks used to guide this study were attachment theory, individual differences model, and meaning reconstruction model. Three research questions were the focus of the qualitative study: what are the lived grief experiences of African American adults who experienced the death of a loved one during the …


The Consequences Of Social Isolation On Early Adolescent Youth: The Rise Of Gender Identity Questioning, Rachele Hauck Apr 2025

The Consequences Of Social Isolation On Early Adolescent Youth: The Rise Of Gender Identity Questioning, Rachele Hauck

Doctoral Dissertations and Projects

The year 2020 brought forth a global pandemic that changed the way human beings went about their daily life. Coinciding at the same point in history, the number of adolescents questioning their gender identity almost doubled. This transcendental phenomenological qualitative study sought to understand the journeys of seven adolescents surviving the stay-at-home mandates put in place by officials attempting to decrease the spread of COVID-19 in a rural midwestern town. These participants identify as a gender that does not align with the gender they were given at birth. Their voices are documented with subject led interviews and attention to expressionistic …


Distinguishing Multisystem Inflammatory Syndrome In Children From Typhus Using Artificial Intelligence: Mis-C Versus Endemic Typhus (Ai-Met), Angela Chun, Abraham Bautista-Castillo, Isabella Osuna, Kristiana Nasto, Flor M Munoz, Gordon E Schutze, Sridevi Devaraj, Eyal Muscal, Marietta M De Guzman, Kristen Sexson Tejtel, Tiphanie P Vogel, Ioannis A Kakadiaris Apr 2025

Distinguishing Multisystem Inflammatory Syndrome In Children From Typhus Using Artificial Intelligence: Mis-C Versus Endemic Typhus (Ai-Met), Angela Chun, Abraham Bautista-Castillo, Isabella Osuna, Kristiana Nasto, Flor M Munoz, Gordon E Schutze, Sridevi Devaraj, Eyal Muscal, Marietta M De Guzman, Kristen Sexson Tejtel, Tiphanie P Vogel, Ioannis A Kakadiaris

Faculty, Staff and Students Publications

Background: The pandemic emergent disease multisystem inflammatory syndrome in children (MIS-C) following coronavirus disease-19 infection can mimic endemic typhus. We aimed to use artificial intelligence (AI) to develop a clinical decision support system that accurately distinguishes MIS-C versus endemic typhus (MET).

Methods: Demographic, clinical, and laboratory features rapidly available following presentation were extracted for 133 patients with MIS-C and 87 patients hospitalized due to typhus. An attention module assigned importance to inputs used to create the 2-phase AI-MET. Phase 1 uses 17 features to arrive at a classification manually (MET-17). If the confidence level is not surpassed, 13 additional features …


Health Crisis And Currency Risk: Fresh Evidence From New Data Sets, Afees A. Salisu, Dinci J. Penzin, Yinka S. Hammed Apr 2025

Health Crisis And Currency Risk: Fresh Evidence From New Data Sets, Afees A. Salisu, Dinci J. Penzin, Yinka S. Hammed

Bulletin of Monetary Economics and Banking

With the aid of a method of predictability analysis that involves a feasible quasigeneralized least squares estimator, we examine the predictive power associated with the newly computed COVID-19 indices, which are disaggregated into six indices for currency market risks (realized volatility of exchange rate). Our sample size covers the period between December 31, 2019, and December 28, 2021. We note mixed outcomes for the major currency markets considered. On average, while the health crisis seems to have heightened the risks associated with Pounds Sterling, Australian Dollar and Canadian Dollar against USD, it exerts a moderating effect on the Euro, Yen …


The Emotions Of Uncertainty: Science, Politics, And The Social Dynamics Of Decision Making, Alisa N. Rogers Apr 2025

The Emotions Of Uncertainty: Science, Politics, And The Social Dynamics Of Decision Making, Alisa N. Rogers

Sociology ETDs

This dissertation examines how social and emotional factors influence attitudes toward science and decision making regarding science-based policy recommendations during the COVID-19 pandemic. I examine boundary work practices among the public as they evaluate experts during the pandemic and the social sources of information people used to construct knowledge. Then I examine the social and emotional factors that participants indicated influenced their own attitude formation and decisions to act regarding public health recommendations during the pandemic. I find that emotions influence each element of the decision process: information gathering, information evaluation, attitude formation, and decisions to act. Affective commitment and …


The Impact Of Covid-19 On Nurses' Feelings, Stress, Coping, And Motivation In Palestinian Treatment Centers Of Corona, † Wafaa Menawi, Shatha Mari, Ahmad Adel Hanani Apr 2025

The Impact Of Covid-19 On Nurses' Feelings, Stress, Coping, And Motivation In Palestinian Treatment Centers Of Corona, † Wafaa Menawi, Shatha Mari, Ahmad Adel Hanani

An-Najah University Journal for Research - B (Humanities)

Background: Frontline nurses of COVID-19 found themselves in an unfamiliar new disease work environment, fighting to adapt and control the stress while working at covid-19 centers in Palestine. Aim: To investigate the impact of COVID-19 on nurses' feelings, stress, coping, and motivation in COVID-19 Palestinian treatment Centers. Method: A descriptive cross-sectional design was conducted between Mid of July to the end of October 2021 by recruiting a purposive sample of 390 nurses who worked at the Ministry of Health during COVID-19 pandemic treatment centers. The nurses filled out the COVID-19 Health Personnel Questionnaire with Cronbach's Alpha > 0.9. Results: Palestinian frontline …


The Impact Of Long Covid On Language Proficiency Across Different School Levels In Hong Kong, Shebe S. Xu, Yixun Li, Wanyi Li, Catherine M. Capio, Winnie W.Y. Tso, Derwin K.C. Chan Apr 2025

The Impact Of Long Covid On Language Proficiency Across Different School Levels In Hong Kong, Shebe S. Xu, Yixun Li, Wanyi Li, Catherine M. Capio, Winnie W.Y. Tso, Derwin K.C. Chan

Health Sciences Faculty Publications

Long COVID, where symptoms persist after recovering from COVID-19, can affect cognitive functions like language. However, little is known about its impact on children’s language skills, especially across different school levels. This study investigated the impact of long COVID on language proficiency among 1244 children (Asian; 53.5% boys) from kindergartens (N = 408, Mage = 4.42 ± 1.26 years), primary schools (N = 547, Mage = 9.69 ± 1.96 years), and secondary schools (N = 289, Mage = 14.97 ± 1.85 years) in Hong Kong. Language proficiency was assessed using the Language Experience and Proficiency Questionnaire (LEAP-Q), which measured speaking, …


Soluble Cd13 Is A Potential Mediator Of Neutrophil-Induced Thrombogenic Inflammation In Sars-Cov-2 Infection, Pei-Suen Tsou, Ramadan A. Ali, Chenyang Lu, Gautam Sule, Carmelo Carmona-Rivera, Serena Lucotti, Yuzo Ikari, Qi Wu, Phillip L. Campbell, Mikel Gurrea-Rubio, Kohei Maeda, Sharon E. Fox, William D. Brodie, Megan N. Mattichak, Caroline Foster, Ajay Tambralli, Srilakshmi Yalavarthi, M Asif Amin, Katarina Kmetova, Bruna Mazetto Fonseca, Emily Chong, Yu Zuo, Michael D. Maile, Luisa Imberti, Arnaldo Caruso, Francesca Caccuri, Virginia Quaresima, Alessandra Sottini, Douglas B. Kuhns, Et Al Apr 2025

Soluble Cd13 Is A Potential Mediator Of Neutrophil-Induced Thrombogenic Inflammation In Sars-Cov-2 Infection, Pei-Suen Tsou, Ramadan A. Ali, Chenyang Lu, Gautam Sule, Carmelo Carmona-Rivera, Serena Lucotti, Yuzo Ikari, Qi Wu, Phillip L. Campbell, Mikel Gurrea-Rubio, Kohei Maeda, Sharon E. Fox, William D. Brodie, Megan N. Mattichak, Caroline Foster, Ajay Tambralli, Srilakshmi Yalavarthi, M Asif Amin, Katarina Kmetova, Bruna Mazetto Fonseca, Emily Chong, Yu Zuo, Michael D. Maile, Luisa Imberti, Arnaldo Caruso, Francesca Caccuri, Virginia Quaresima, Alessandra Sottini, Douglas B. Kuhns, Et Al

School of Medicine Faculty Publications

The soluble variant of the ectopeptidase CD13 (sCD13), released from the cell surface by matrix metalloproteinase 14 (MMP14), is a potent pro-inflammatory mediator, displaying chemotactic, angiogenic, and arthritogenic properties through bradykinin receptor B1 (B1R). We revealed a link between sCD13 and amplified neutrophil-mediated inflammatory responses in SARS-CoV-2 infection. sCD13 was markedly elevated in patients with COVID-19 and correlated with disease severity and variants, ethnicity, inflammation markers, and neutrophil extracellular trap formation (NETosis). Neutrophils treated with sCD13 showed heightened NETosis and chemotaxis, which were inhibited by sCD13 receptor blockade. Meanwhile sCD13 did not induce platelet aggregation. Single-cell analysis of COVID-19 lungs …


Tutoring And Its Impact On Mitigating Covid-19 Reading Learning Loss In A Rural Title I School District For 3rd Grade Students, Julie Nicole Goodin Apr 2025

Tutoring And Its Impact On Mitigating Covid-19 Reading Learning Loss In A Rural Title I School District For 3rd Grade Students, Julie Nicole Goodin

Student Theses and Dissertations

This mixed-methods study evaluated the impact of a tutoring program on third-grade students' reading achievement, focusing on rural Title I schools. The research used the Kellogg Logic Model to assess the program's short-term outcomes. It analyzed universal reading data for one hundred and three third-grade students and gathered the perspectives from nineteen stakeholders, including teachers, parents, and administrators. The researcher assessed the long-term outcomes by analyzing data on third-grade students' overall academic reading growth and by examining the stakeholders' perceptions of the program's effectiveness. The themes for the study from the participants included the benefits of tutoring, bus transportation, use …


Duty To Care And Job Turnover Intention In The Post-Pandemic Nursing Workforce, Cathleen A. Lopez Apr 2025

Duty To Care And Job Turnover Intention In The Post-Pandemic Nursing Workforce, Cathleen A. Lopez

Nursing Theses and Dissertations

Natural and human-made disasters are increasing in number and intensity. In 2020, approximately 688.3 million people required assistance from disaster response personnel. During a disaster or pandemic, nurses must weigh their personal and/or family safety against the ethical code of caring for others. The purpose of this convergent mixed-methods study was to examine duty to care and job turnover intention of registered nurses working in patient-facing roles. A convergent mixed method design was used to address research questions by employing the Nash Duty to Care Scale (NDCS) and the Turnover Intent Scale (TIS-6). Open-ended survey questions were used to explore …