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Comparison Of Respiratory Responses To Exercise Under Different Heat-Stressful Environments Between Oral Contraceptive And Naturally Menstruating Ovulating Female Athletes, Nanako Hayashi, Toby Mündel, Tze Huan Lei, Claire Badenhorst

Research outputs 2022 to 2026

The present study conducted a secondary analysis of previous data (Lei et al., 2017, 2019) to compare exercise-induced respiratory responses under heat stress between the early follicular (EF)/ quasi -EF and mid-luteal (ML)/ quasi -ML phases in naturally menstruating and oral contraceptive pill (OCP)-using female athletes. Additionally, the study aimed to examine the associations between respiratory responses, thermoregulation, and hormonal profiles within each group. Sixteen endurance-trained female athletes participated: eight with a natural menstrual cycle (NM group) and eight using OCP (OCP group). Each participant completed four trials, comprising fixed-intensity cycling (at 125 and 150 W) followed by a 30-min …

Zinc-Based Amendments And Zn-Solubilizing Beneficial Bacteria Mitigate Lead-Induced Toxicity In Chickpea (Cicer Arietinum L.), Mohammad Shahid, Mohammad Abul Farah, Khalid Mashay Al-Anazi, Leonard Koolman

Research Outputs: 2025-Present

Lead (Pb) is a toxic metal that disrupts plant physiological processes and poses significant human health risks. Fertilizers, nanomaterials, and mineral-solubilizing plant growth-promoting rhizobacteria (PGPR) support phytoremediation as an emerging, eco-friendly strategy for metal detoxification by improving nutrient availability and minimizing metal toxicity in plants. This study explored the interactions of Zn-fertilizer, zinc-oxide nanoparticles (ZnO-NPs), and Zn-solubilizing Enterobacter cloacae (Zns-Ec) in mitigating Pb-induced phytotoxicity in 50, 100, and 150 mgPbkg ⁻¹ soil-stressed chickpea. Under Pb stress. Zn, ZnO-NP and Zns-Ec significantly (p < 0.05) improved root biomass (23.4, 52.3, and 71.4%), chl a (21.2, 26.5, and 39.8%), and carotenoids (26.7, 29.7 and 45.7%) in chickpea subjected to 50 mgPbkg ⁻¹ soil. Zn, ZnO-NP and Zns-Ec interactions reduced lipid peroxidation (LPO), hydrogen peroxide (H ₂O ₂) …

Leptinotarsa Texana Schaeffer And Gargaphia Arizonica Drake & Carvalho As Potential Biocontrol Agents For The Noxious Weed Solanum Elaeagnifolium Cav, Samikshya Subedi, Stephanie L. Kasper, Alexis Racelis, Greg Lefoe, Rupesh R. Kariyat

School of Earth, Environmental, & Marine Sciences Faculty Publications

Silverleaf nightshade (Solanum elaeagnifolium Cav.; SLN) is a perennial forb native to the southern United States, Mexico and South America that has become a serious agricultural weed across the world. Biological control has emerged as a significant alternative for the management of (SLN) due to the challenges and high costs associated with chemical and mechanical controls. In this study, we used a combination of field and laboratory studies to (1) explore the fundamental and realized host ranges of two North American insects, Leptinotarsa texana Schaeffer and Gargaphia arizonica Drake & Carvalho and (2) assess their suitability as potential biological …

Development Of Novel Small Molecule Therapeutics For Myotonic Dystrophy, Xhesika Azis

Biological Sciences

Myotonic Dystrophy type 1 (DM1) results from expanded CUG repeat RNA that sequesters MBNL proteins and disrupts alternative splicing. Small molecules that bind toxic repeat RNA and release MBNL proteins represent a promising therapeutic strategy. This thesis examines newly synthesized modified polycyclic compounds (MPCs) engineered to target CUG RNA with enhanced specificity and efficacy. Through Suzuki–Miyaura coupling and benzoquinone-mediated cyclization, MPC03 was synthesized and characterized by NMR and LC–MS.

The biological activity of these compounds was assessed in DM1 patient-derived myotubes and fibroblasts. MPC03 consistently produced dose-dependent rescue of multiple MBNL-regulated exons, restoring splicing patterns toward those observed in healthy …

The Lived Experiences Of Black Female Leaders At An Hbcu Whose Predecessors Are Non-Black Females, Patricia Pearsall Williams

All Dissertations

This study used a rigorous qualitative hermeneutic phenomenological approach to examine the lived experiences of eight Black female leaders at Historically Black Colleges and Universities (HBCUs) in one of the following geographic regions in the United States: the South Atlantic, Eastern South Central, and West South Central (U.S. Census Bureau, 2022). The leadership roles for this study included, but were not limited to, president, senior vice president, assistant provost, vice president, dean, executive director, director, assistant director, associate director, department head, manager, or supervisor.

By examining the essences, nuances, and differences of these experiences, the researcher aimed to understand how …

Machine Learning Applications: Cell Tracking And Nonparametric Estimation Of Non-Smooth Divergences, Mina Mahbub Hossain

All Graduate Theses and Dissertations, Fall 2023 to Present

This thesis brings together two important research directions: how to compare different sets of data more accurately, and how to better understand how brain cancer cells move and change shape.

In the first part, we look at a problem in statistics: measuring how different two data sources are from each other. Traditional methods often make strong assumptions, which may not always hold in real situations. Our approach avoids those assumptions by using an ensemble method, a way of combining many weak estimators into one stronger result. This makes the method more flexible and reliable, especially when dealing with complex or …

Utilizing Diatoms In Wastewater Treatment For Pollutant Removal, Ceaira D. Howard

All Graduate Theses and Dissertations, Fall 2023 to Present

Wastewater treatment systems are increasingly challenged by a complex mix of pollutants including excess nutrients, organic dyes, and persistent chemicals like per- and polyfluoroalkyl substances (PFAS). Conventional treatment technologies often struggle to effectively and affordably remove these contaminants. This study explores the use of two diatom species, Phaeodactylum tricornutum and Navicula cryptocephala var. veneta, both single-celled microalgae with silica-based cell walls, as an environmentally sustainable approach to tertiary wastewater treatment. Diatoms offer dual functionality through surface adsorption properties and metabolic flexibilities, making them promising candidates for integrated treatment strategies.

To test the trophic flexibilities of diatoms, P. tricornutum was …

Quicklime-Based Self-Healing Concrete For Bridge Deck Applications, Mehrnoosh Nazari

All Graduate Theses and Dissertations, Fall 2023 to Present

Concrete is one of the most widely used construction materials in the world. However, over time, it can crack and deteriorate, especially on roads and bridges exposed to harsh weather and deicing salts. Inspired by the long-lasting durability of ancient Roman concrete, this study explores the self-healing capabilities of concrete incorporating quicklime (calcium oxide) aggregates to extend the service life of bridge decks. For this purpose, three concrete mixtures were developed using local materials: one without quicklime (C-Q 0%) and two with 2% (C-Q 2%) and 4% quicklime (C-Q 4%). These mixtures were tested for fresh properties, strength, durability, and …

Impacts Of Including Sprouted Barley In The Diet Of Beef Cattle On Production, Ruminal Health, And Meat Quality, Zachary C. Crump

All Graduate Theses and Dissertations, Fall 2023 to Present

Beef producers in the United States are working to meet rising global demand for animal protein while facing major challenges such as drought, climate uncertainty, and rapid urbanization. These issues make it difficult to produce consistent and dependable feed, pushing producers to explore new ways to grow feed using fewer natural resources. Vertical farming systems are one option that can grow sprouted cereal grains indoors throughout the year while using decreased land and water than traditional agriculture. Sprouted barley grows within six to seven days and may serve as a nutrient dense alternative feed source for cattle at several stages …

Live And Let Fly: Assessing Threats To California Condors, Molly Astell

Boise State University Theses and Dissertations

California condors (Gymnogyps californianus) are a critically endangered species that face threats, both anthropogenic and natural, that slow recovery of their population. The leading causes of death of condors are lead toxicosis, predation, trauma, fire, and collision and electrocution at power lines. As a long-lived and slow-maturing species, each death is consequential and understanding when and where threats occur can greatly benefit management and mitigation. Although the focus of extensive mitigation efforts, lead toxicosis remains the leading cause of death for condors. There has been less effort dedicated to addressing the second-leading anthropogenic threat, interactions with power lines. Such efforts …

Integrating Neural Control And Finite Element Muscle Modeling: A Predictive Neuromusculoskeletal Framework For Investigating Neurodegenerative Disease, Colton Babcock

Boise State University Theses and Dissertations

Neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) disrupt the interplay between neural control and musculoskeletal function, leading to progressive motor decline and loss of force control and production. Traditional experimental and clinical approaches are limited in their ability to capture the multiscale, nonlinear mechanisms driving these impairments. This dissertation presents a novel predictive neuromusculoskeletal (NMS) modeling framework that integrates physiologically accurate motor neuron dynamics with three-dimensional finite element (FE) muscle models. Using subject-specific muscle geometry and fiber architecture of the tibialis anterior, the model simulates realistic force generation under both healthy and ALS-affected conditions. The neural component incorporates a …

Harnessing The Mechanical And Gelation Behavior Of Tyramine-Substituted Silk Fibroin Bioinks Through Integration Into A Modular And Low-Cost 3d Bioprinting Platform, Sourjjadeepta Biswas

Boise State University Theses and Dissertations

3D printing has become an indispensable tool in research labs across the globe. Yet, when it comes to bioprinting with custom or sensitive bioinks, accessible options remain limited. Commercial systems are often prohibitively expensive and restricted to proprietary materials, while DIY setups frequently lack the precision and compatibility needed for biologically relevant printing. Moreover, tunable bioinks that align with real-world biological constraints are still hard to come by. To address these gaps, we developed a modular, low-cost bioprinting platform tailored for tyramine-substituted silk fibroin (TA-SF) hydrogels-biocompatible materials known for their rapid gelation, tunable stiffness, and potential to support cell differentiation …

Leveraging Disparate Wildland Fire Datasets To Address Longstanding Fire Management Questions, Kendra Fallon

Boise State University Theses and Dissertations

While wildfire season is perceived as occurring in the warm months, and expanding, wildfire management is a year-long process. Juxtaposed to wildfire seasons are the reactive seasons of mitigating for post-fire effects, namely first-order effects of potential hydrological impacts in burn footprints, and the proactive implementation of fuels treatments to modify fire behavior to lessen the reactive workload. In this dissertation, I focus on answering lingering questions that are critical to the management of the shoulder seasons of wildfire season. To assist in resource allocation and identification of post-hydrological risks, I present a model identifying the major drivers of soil …

Deep Reinforcement Learning For Adaptive Mesh Refinement: A Training Parameter Study, Antone Chacartegui

Boise State University Theses and Dissertations

Adaptive mesh refinement (AMR) enables efficient solution of partial differential equations by dynamically allocating computational resources to regions requiring higher resolution. It has been demonstrated that deep reinforcement learning agents could learn effective mesh adaptation policies. However, practical deployment requires a systematic understanding of how training parameters affect performance across diverse computational scenarios.

This thesis presents a parameter optimization study analyzing the relationship between deep reinforcement learning for adaptive mesh refinement (DRL-AMR) training parameters and model performance. We implement an independent DRL-AMR system with a discontinuous Galerkin solver and actor-critic (A2C) algorithm for one-dimensional linear advection. The study explores four …

Modeling The Deleterious Effects Of An Endogenously Generated Apolipoprotein-E4 Fragment In Transgenic Zebrafish, Emily Egan

Boise State University Theses and Dissertations

Harboring the apolipoprotein E4 allele (APOE4) is the strongest genetic risk factor for late-onset Alzheimer’s disease, yet the mechanisms by which the expressed protein contributes to neurodegeneration remain unknown. Previous studies suggest that proteolytic cleavage of ApoE4 generates amino-terminal fragments that are neurotoxic and may drive cellular dysfunction. To investigate the deleterious effects of one such fragment, nApo_E1-151, in a living vertebrate model, we developed a transgenic zebrafish line using Tol2-mediated transgenesis to endogenously express nApo_E1-151 under the neuron-specific HuC/D promoter. This model utilizes the zebrafish’s genetic accessibility, embryo and larva transparency, and rapid development ex utero to study the …

Understanding Students’ Psychological Needs Satisfaction And Frustration In A Gamified Biology I Course: A Mixed Method Study, Shakiyla Huggins

Boise State University Theses and Dissertations

The purpose of this study was to examine how gamification impacts student motivation in higher education through the framework of Self-Determination Theory (SDT). While previous research has linked gamification to engagement, this study addressed a gap by directly measuring students' satisfaction and frustration with their basic psychological needs — autonomy, competence, and relatedness — in a gamified undergraduate Biology I course. A convergent parallel mixed methods design was employed. Quantitative data were collected using the Basic Psychological Need Satisfaction and Frustration Scale (BPNSFS) from 22 students who completed both pre- and post-course surveys. Qualitative data were drawn from student reflection …

Shifting Grounds: Knowledge, Power, And Place In Changing Western Rangelands, Molly C. Levy

Boise State University Theses and Dissertations

Public rangelands in the American West are sites of enduring contestation, where ecological change, competing values, and institutional complexity converge. Long-standing debates over livestock grazing, wildlife conservation, and land stewardship highlight fundamental questions of whose knowledge counts, whose authority is legitimate, and how resource use should adapt under shifting social and ecological conditions. This dissertation examines the intersections of knowledge, power, and land use in collaborative governance of contested landscapes. Using the Thunder Basin ecoregion (TBER) in northeastern Wyoming as a case study, I adopt a mixed-methods approach that integrates qualitative interviews, participant observation, archival research, and quantitative analysis of …

A Comparative Study Of Novel Methods For Variances, Taoreed Muritala

Boise State University Theses and Dissertations

Understanding variability is fundamental to knowledge advancement across various disciplines, including manufacturing, clinical research, biology and genetics. Population variances play a crucial role in processes such as quality control, treatment evaluation and the interpretation of biological mechanisms. However, statistical procedures for comparing variances across multiple populations remain less developed than those for comparing means. Classical omnibus tests, such as Bartlett's and Levene's, can detect overall variance heterogeneity but fail to identify which populations differ, thereby limiting their usefulness in multi-population analyses and increasing the risk of inflated family-wise error rates through repeated testing.

This thesis develops and evaluates three multiple …

Evaluation Of High Concentration Dissolved Oxygen Delivery On Wastewater Treatment Plant Performance, Gregor Ethan R. Posadas

Boise State University Theses and Dissertations

Microorganisms are used in wastewater treatment plants (WWTPs) to transform constituents and depend on dissolved oxygen (DO) for growth. Limitations in traditional treatment methods pose inefficiencies in performance relative to constituent removal. This study involved monitoring the performance of a selected WWTP located in Greenleaf, Idaho that was retrofitted with a high concentration DO delivery system. The WWTP was selected due to its small scale (classified as a minor discharge facility with a design flow <1 MGD) and capability of being retrofitted with a high concentration DO delivery system proprietary to BioSolution Holdings Co., Ltd. This study aimed to monitor the effects of delivering higher DO concentrations in the WWTP in conjunction with validating the performance and function of the retrofitted high concentration DO delivery system. The performance of the selected WWTP was monitored over the course of one year to capture seasonal fluctuations.

Significant changes in WWTP constituent treatment induced by higher DO concentrations were observed at various points within the treatment processes. Monitored parameters included DO, temperature, …

Harnessing Bioscaffold-Coupled Stimulation Through Electroactive Graphene Foam For Enhanced Cellular And Mechanical Responses: Applications In Cartilage Tissue Engineering, Mone't Sawyer

Boise State University Theses and Dissertations

Osteoarthritis is a leading cause of joint degeneration, with limited treatment options that fail to restore native cartilage. Tissue engineering offers a promising strategy by combining cells, scaffolds, and bioactive cues to regenerate functional tissue, though challenges remain in developing systems that integrate and precisely control these signals in three-dimensional environments. This work establishes a scaffold-coupled electrical stimulation (ES) platform using electroactive graphene foam (GF) to modulate cellular and mechanical responses relevant to cartilage tissue engineering. Custom stereolithography-printed bioreactors were developed to deliver low-voltage biphasic square waves (20–60 mVpp, 1 kHz) directly to GF scaffolds under submerged culture, maintaining waveform …

Stimulation And Recording Interfaces For Data Transmission To And From A Micro Neural Stimulation Device, Morgan Riley

Boise State University Theses and Dissertations

Advancements in neuromodulation for treating neurological disorders increasingly rely on selective peripheral nerve stimulation rather than whole-nerve activation. Traditional approaches engage all fascicles, causing off-target effects such as involuntary muscle contractions and pain. To address these challenges, this research proposes a minimally invasive microdevice that integrates wireless galvanic impulse communication with an epineural multi-contact nerve cuff. This design facilitates high-throughput, low-power stimulation, recording, and data transfer. Development efforts include optimizing neural stimulation protocols, validating deep tissue galvanic transmission, and fabricating a multi-channel nerve cuff for stable electrode–tissue interfacing. In parallel, custom depth-controlled intramuscular arrays enable high-density electromyography (EMG) recording during …

High Test-Retest Reliability Of Nucleus Accumbens Activity During Reward Anticipation, Nathaniel Bouton

Graduate Theses and Dissertations

Recent research has questioned the reliability of Functional Magnetic Resonance Imaging (FMRI). The findings suggest poor test-retest reliability of FMRI measures across brain areas and tasks, and specifically in subcortical brain areas during reward-related tasks. Further, data from the Adolescent Brain Cognitive Development (ABCD) study showed low reliability and low stability of the fitted coefficients from whole-brain regression analyses of the Monetary Incentive Delay (MID) task. However, optimizing methods might improve reliability, for example: (1) acquiring single-band rather than multi-band FMRI sequences, (2) extracting raw activity rather than fitted coefficients, and (3) honing analyses to target brain areas during specific …

Emotion Regulation Flexibility And Well-Being In College Athletes In Aesthetic Sports, Kaitlyn D. Chamberlain

Graduate Theses and Dissertations

This study examined emotion regulation flexibility and well-being (including psychological well-being, physical well-being, perceived sport performance and worth of sport participation) in athletes in aesthetic sports. This population experiences high environmental demands and constraints and thus low control over their environment. Collegiate athletes within aesthetic sports and female athletes experience specific social factors and demands that threaten their well-being, compared to those experienced by male athletes and athletes within non-aesthetic sports. Consistent with the transactional theory of stress and coping, individuals with less power to regulate their environment will require greater ability to regulate themselves in accordance with their changing …

Perception Of Drinking Water Quality Among Arkansas Residents, Kolade Olawale Olatunde

Graduate Theses and Dissertations

Objective: Perceptions of drinking water quality influence public trust, water consumption behaviors, and the willingness to invest in infrastructure improvements. Despite the importance of safe drinking water, regional and socio-economic disparities impact how residents perceive their tap water and their readiness to pay for enhancements. While past research indicates that negative views of tap water quality have resulted in behavioral changes, the connection between perception and actual household water usage remains ambiguous. This study aims to investigate how perceptions of drinking water quality differ across regions in Arkansas and how residents are willing to invest in quality improvements. Method: A …

A Phenomenological Exploration Of Black International Graduate Students’ Experiences In Building A Sense Of Belonging And Community At A Predominantly White Southern University, Hilda Solange George

Graduate Theses and Dissertations

Black international graduate students’ experiences navigating and developing a sense of belonging and community at higher educational institutions in the United States and particularly at predominantly white institutions have received minimal attention in scholarly inquiries, despite their cultural, intellectual, and financial contributions to host institutions and the country. To fill this gap in the existing literature, this hermeneutical phenomenological study aimed to gain a nuanced and in-depth understanding of Black international graduate students' perceptions of their sense of belonging and community at a predominantly white southern university (PWSU) in the United States. Guided by the research questions and the Black …

Agricultural Practices’ Impact On Soil Health Indicators In Mid-South U.S. Crop Production Systems, Katherine Suzanne French

Graduate Theses and Dissertations

Soil health and regenerative agriculture are concepts gaining popularity across global agriculture systems. The effect of sustainable farming practices such as nutrient management, cover crops, adoption of no-tillage, and residue retention on crop yield, as well as environmental resilience, is increasingly being studied. This research aimed to evaluate the impacts of (i) cover cropping and nutrient management, and of (ii) soil sampling depth and timing on indicators of soil health in various mid-southern irrigated row crop systems. Soil health indicators like soil organic matter (SOM), carbon dioxide respiration (CDR), beta-glucosidase enzyme activity (BG), permanganate oxidizable carbon (POXC), and the soil …

Hyperspectral Indicators And Characterization Of Glyphosate-Induced Stress In Common Lambsquarters (Chenopodium Album L.), Mario Andrés Soto Valencia

Graduate Theses and Dissertations

Hyperspectral sensing enables detection of herbicide stress in weeds, but practical use requires strategies for redundancy control, rating variability management, and evaluator bias mitigation. This thesis evaluates common lambsquarters (Chenopodium album) under glyphosate exposure, aiming to identify key wavelengths, construct vegetation indices, and improve injury modeling. Greenhouse experiments used dimensionality reduction methods (principal component analysis, Relief F, Bayesian discriminant analysis) to isolate 34 unique wavelengths from about 3,200 bands. Calibration data were collected 14 days after treatment (DAT) to support wavelength selection and model development, while data from 27 DAT were used for independent validation. Class comparisons across six statistically …

Evidence Of Backwater Morphodynamics In Stratigraphy On Earth And Mars: Implications For Ancient Mars, Cory Mitchell Hughes

Graduate Theses and Dissertations

Geologic evidence indicates that liquid water once flowed in abundance across the martian surface. For this reason, in the search for evidence of extraterrestrial life, Mars represents a prime target for scientific inquiry. River systems encode climatic and environmental signals in their deposits on Earth and Mars, often in fan-shaped landforms (e.g., alluvial fans, river deltas, etc.). Distal fan-shaped deposits (i.e., river deltas), in particular, act as a relatively high-fidelity record of dynamic geologic processes. As such, NASA frequently sends rovers to locations on Mars’ surface with hypothesized river deltas (e.g., Perseverance and Jezero crater). Problematically, there are many different …

Transcriptomic And Contractile Adaptations In Skeletal Muscle In A Rodent Model Of Anorexia Nervosa, Oscar Armando Vicen

Graduate Theses and Dissertations

BACKGROUND: Anorexia Nervosa (AN) is a psychiatric disorder marked by severe chronic caloric restriction and is primarily diagnosed through psychological and behavioral symptoms. AN has the highest mortality of any psychiatric disorder with an increased risk of all-cause mortality. Many individuals with a history of AN experience incomplete recovery despite intervention treatment. Skeletal muscle molecular mechanisms under chronic energy deprivation remain poorly understood. PURPOSE: To investigate transcriptomic profiles of the gastrocnemius muscle following one month of a rodent model of AN. This study analyzed whether the molecular changes correlate with collected muscular force data to provide a comprehensive understanding of …

Towards Vision-Brain Understanding At Scales: From Classical To Quantum Machine Learning Approaches, Xuan-Bac Nguyen

Graduate Theses and Dissertations

In recent years, large-scale learning approaches such as unsupervised and self-supervised learning have revolutionized artificial intelligence. These methods enable machines to learn high-level representations without explicit human supervision, achieving remarkable success across vision, language, and multimodal tasks. However, such advances come at a cost—they rely on massive datasets, billions of parameters, and extensive computational resources. Despite these achievements, artificial systems still fall short of the remarkable learning efficiency of the human brain, which can infer, adapt, and generalize from limited experiences. This gap motivates a deeper exploration of how biological intelligence acquires knowledge and how these principles can inspire the …