Digital Commons Network^™

Using Spiderwebs To Capture Airborne Environmental Dna (Edna) To Detect Animal Biodiversity In An Urban Park, Sabriya Ann Seid, Leonardo Gonzalez-Smith, Josephine Campos, Demian A. Willette

Cities and the Environment (CATE)

Environmental DNA (eDNA) is the genetic material shed by organisms in the environment. It has emerged as a powerful resource for assessing biodiversity, particularly in aquatic settings. The application of eDNA methods in terrestrial environments is less developed, with researchers still exploring collection methods of eDNA from the air. One novel approach recently trialed is the use of spiderwebs, a passive, natural material whose sticky silk threads can capture tiny airborne particles, including eDNA. Here, we investigated the use of spiderwebs for airborne eDNA collection as part of a broader survey of biodiversity at the urban Ascot Hills Park in …

Assessment Of Residents’ Knowledge, Attitude And Perception Of Climate Change Issues In Ibadan South West Local Government, Oyo State, Nigeria, Samson Olanrewaju, Samuel Oyeniyi, Sola Atoyebi, Modupeola Okubena, Chinedu Abazu, Emeka Adibe

Cities and the Environment (CATE)

This study examines residents’ knowledge, attitude, and behavioural responses to the impacts of climate change in Ibadan South West Local Government Area, Oyo State, Nigeria. It evaluates residents’ awareness of climate change, analyses their behavioural responses to climate change impact, and identifies household characteristics that influence knowledge, attitude, and perception of climate change in the area. The study utilised a mixed-methods research approach, using such instruments as questionnaire administration and interviews. The study employed a multistage sampling technique where a total of seven (7) Enumeration Areas (EAs) were selected, and 206 questionnaires were administered to residents of the area. These …

Psychologists’ And Psychiatrists’ Views On Criminal Behavior, Fetal Alcohol Spectrum Disorder, And Federally Sentenced Indigenous Women In The Prairie Region And British Columbia, Rina Asghar

Walden Dissertations and Doctoral Studies

The overrepresentation of federally sentenced Indigenous women in Canada reflects longstanding structural and systemic injustices within the criminal justice system. Constituting approximately 5% of the female population, Indigenous female offenders are disproportionately represented, especially in maximum security facilities and structured intervention units. This qualitative study examined psychologists’ and psychiatrists’ perspectives on the potential role of fetal alcohol spectrum disorder (FASD) related neurocognitive impairments in increasing justice system involvement among Indigenous women in Western Canada. Guided by the multidimensional Indigenous developmental framework, which integrates historical trauma theory and attachment theory, nine psychologists and one psychiatrist were interviewed in semi-structured interviews. The …

The Agreement Between Pulse Oximetry And Measured Arterial Oxygen Saturations In Postoperative Functionally Univentricular Patients, Fabio Savorgnan, Sebastian Acosta, Joshua Prabhu, Pranathi Pilla, Vikram Shah, Saul Flores, Rohit S Loomba

Faculty, Staff and Students Publications

Background: Pulse oximetry is widely used to estimate arterial oxygen saturation, yet accuracy may vary for a number of reasons. Data on children with functionally univentricular circulation are limited. The primary aim of this study was to evaluate the agreement between arterial oxygen saturation measured by blood gas and pulse oximetry in children with functionally univentricular circulations. Methods: A retrospective analysis was performed of paired arterial blood gas and pulse oximetry oxygen saturation measurements following Norwood, Glenn, or Fontan procedures. Signed difference was defined as arterial oxygen saturation by blood gas-arterial oxygen saturation by pulse oximetry. Bland-Altman analyses, …

Western Conifer Seed Bug (Leptoglossus Occidentalis), Emilie Demard

All Current Publications

This fact sheet provides information on the western conifer seed bug, including native range, life cycle, plant hosts, symptoms and damage, and management options.

Closing The “Extreme Circumstances” Gap: The Legality Of Nuclear Weapons When The Survival Of A State Is In Question, Christopher J. Hart

International Law Studies

There is a gap at the heart of the law governing the use of nuclear weapons. Repeated threats by Russian leaders to use nuclear weapons against Ukraine highlight the urgency of closing this gap. This article reviews the central holding of the 1996 International Court of Justice advisory opinion on the Legality of the Threat or Use of Nuclear Weapons. The article focuses on the controversial “extreme circumstances” clause, in which the ICJ stated that it could not determine the legality of using nuclear weapons when the survival of a State was in question. This left open the questions …

Genetic Variants And Molecular Components Associated With Metabolic Dysfunctional-Associated Steatotic Liver Disease And Depression: Shared Association Of Adamts7 And Thrap3, Eron G. Manusov, Vincent P. Diego, Marcio A. Almeida, Jacob A. Galan, Kathryn Herklotz, Edwardo Abrego Ii, Habiba Sultana, Luis A. Peña Marquez, Marco Arriaga, Marcelo Leandro, Juan M. Peralta, Ana C. Leandro, Tom Howard, Joanne Curran, Sandra Laston, John Blangero, Sarah Williams-Blangero

Human Genetics Publications

Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) and depression frequently occur together. Identifying the genes that influence both MASLD and depression may facilitate the discovery of biological pathways associated with disease risk.

Methods: We recruited 525 participants from Mexican American families living in the Rio Grande Valley of south Texas. We collected clinical data, biometric measurements, hepatic health assessments using Vibration-Controlled Transient Elastography (VCTE), and depression evaluations determined with the Beck Depression Inventory-II. We estimated the heritability (h2) of MASLD-related measures, depression status, aspartate aminotransferase (AST), alanine aminotransferase (ALT), the AST/ALT ratio, and Vibration-Controlled Transient Elastography measurements. For each gene, …

On-Resin Diamsar-Conjugated Cd38-Targeted Peptides And Their Inverso And Dimeric-Inverso Analogs For Pet Imaging Of Multiple Myeloma, Amit Kumar Sharma, Rui Tang, Alexander Zheleznyak, Brad Manion, Erin Teubner, Julie L Prior, Tommy Bauer, Michael Riley Dyer, Stephen Lees, Kimberly Kelly, Monica Shokeen

2020-Current year OA Pubs

CD38 is an established biomarker of multiple myeloma (MM), and peptide-based radiopharmaceuticals targeted to this receptor offer a route to molecularly specific imaging. In this work, we identified a novel CD38-targeted peptide sequence (HAPWFRGGGGS) through phage display and synthesized it using automated solid-phase peptide synthesis. The peptide was modified by introducing a PEG

Beyond Borders: Exploring The Diversity, Practices, And Influences Of Feminism In Baguio City’S Contemporary Society, Patricia Josh Fate Alcantara, Asher Luis Cunan Badecao Iv, Clint Yuan Vista Castro, Alyza Faye Balbas Cutit, Naedaly Balagot David, Francesco Riane Bareng Pineda

DLSU Senior High School Research Congress Conference Proceedings

Historical research documents feminism's evolution from 19th-century suffrage movements to modern intersectional approaches. Though there are gaps in understanding how personal experiences and contexts, such as cultural and socio-economic, influence current feminist practice. This study investigates how lived experiences shape contemporary feminist engagement in Baguio City, Philippines. Using a descriptive phenomenological analysis of face-to-face interviews with a total of nine participants, the study identifies the following: results reveal generational divides, with younger participants developing progressive, digitally-informed feminist consciousness, while economic realities constrain activist participation for marginalized groups. Practical manifestations of feminism emerge through four daily practices: (1) conscious use of …

Reshaping Library Programming For Graduate Students Through Strategic Partnerships And Adaptation, Brian Vetruba, Caroyn Bishoff, Kate Peterson

Transforming Libraries for Graduate Students

In the wake of Covid-19, support structures dedicated to graduate student success at the University of Minnesota, Twin Cities (UMN) underwent dramatic shifts. Centralized in-person events for graduate students were discontinued, departmental identities strengthened, and library outreach responsibilities were reshaped by institutional changes, including a reduction of library staff. This panel examines how academic libraries can adapt and innovate with decreased capacity to meet the diverse needs of graduate students. Panelists will share strategies for expanding campus partnerships and sustaining and scaling initiatives that equip graduate students – especially first-year, international, and BIPOC students – with essential research skills and …

Ancestral Rites And Tablets As A Site Of Contestation Between Confucian Filial Piety And Catholicism: The Cases Of Chinese Confucian Yan Mo And Korean Catholic Yun Ji-Chung, Mideum Hong

Journal of Global Catholicism

This essay examines how the Confucian practice of filial piety, particularly as expressed through ancestral rites and tablets, became a focal point of contention in the encounters between Confucianism and Catholicism. Focusing on the cases of the Chinese Catholic Yan Mo and the Korean Catholic martyr Yun Ji-chung, I argue that the different historical and cultural contexts in China and Korea significantly shaped how each figure understood and responded to the practice of ancestral rites. While Catholicism spread globally, local converts developed distinct theological interpretations rooted in their respective cultural traditions. Although Yan Mo and Yun Ji-chung reached divergent conclusions …

The Level Of Physical Activity And The Feeling Of Stress In Difficult Life Situations Among Refugees From Ukraine, Bartosz Gondek, Iwona Bonisławska, Milena Lachowicz

Baltic Journal of Health and Physical Activity

Background: Russia's attack on Ukraine in February 2022 started the largest armed conflict in Europe since World War II. In the face of danger, crowds of civilians decided to leave their homes and escape, among others, to Poland in search of shelter. Materials and methods: The research was conducted on groups of refugees from Ukraine who registered in the first days of the war in Sopot and Pruszcz Gdanski. The refugees came from Kharkov, Mariupol, Kherson, Zaporizhzhia, and western Ukraine (not involved in hostilities). People from the war zone areas mostly came with only hand luggage. The respondents were divided …

Rare Complications Of Chronic Rhinosinusitis Associated With Nasal Polyps And Osseous Metaplasia, Michael Ritz, Alaina Rubenacker-O’Dell, Faith Olson, Ilya Fonarov

Journal of Community Hospital Internal Medicine Perspectives

Chronic rhinosinusitis with nasal polyps (CRSwNP) is typically a benign condition; however, osseous metaplasia (OM), skull base erosion, and intracranial extension are rare complications, especially in young patients. Reporting such cases is important to increase awareness of unusual presentations of CRSwNP and guide management. We report the case of an 18-year-old male with a history of asthma and prior polypectomy who presented with worsening frontal headaches, subtle visual changes, and right eye proptosis. Imaging revealed extensive pansinusitis with complete frontal sinus opacification, bony erosion of the anterior skull base, and evidence of intracranial and orbital extension. The patient underwent endoscopic …

Alk-Negative Anaplastic Large Cell Lymphoma Presenting As Back Pain, Khalid Javed, Mariah Malak Bilalaga, Sareema Adnan, Ramya Vasireddy, David Blackwood, Christopher Haas

Journal of Community Hospital Internal Medicine Perspectives

Anaplastic lymphoma kinase (ALK)-negative anaplastic large cell lymphoma (ALCL) is a distinct subtype of mature T-cell non-Hodgkin lymphoma characterized by large, strongly positive CD30 lymphoid cells that lack expression and rearrangement of the ALK gene. Here, we present a unique case of ALK-negative ALCL in a 34-year-old male patient who presented with acute on chronic back pain. Initial emergent MRI spine demonstrated lytic changes of L3 and L4 with probable psoas fluid collection, with high suspicion for Pott’s disease. However, subsequent work-up including a CT-guided bone biopsy revealed ALK-negative ALCL.  Patient underwent radiation to his lumbar spine and psoas muscle, …

The Impact Of Social Determinants Of Health On Chronic Diseases: A Narrative Review, Farooq Hyder, Laraib Naeem Arain, Abdullah Ashraf, Abida Perveen, Hina Pervaiz

Journal of Community Hospital Internal Medicine Perspectives

Chronic diseases such as cardiovascular disease, diabetes, chronic respiratory disorders, and certain cancers are leading causes of morbidity and mortality worldwide. While biological and behavioral factors contribute to their development, growing evidence indicates that social determinants of health (SDOH) play a fundamental role in influencing chronic disease outcomes. SDOH include socioeconomic status, education, employment, housing conditions, neighborhood environment, access to nutritious food, and availability of healthcare services. These factors not only shape individual health behaviors but also determine access to preventive care, disease management resources, and overall quality of life. Individuals and communities facing socioeconomic disadvantage are disproportionately affected by …

Food Insecurity’S Influence On Obesity, Hypertension, And Diabetes In Rural Vermont And Adirondack New York, Lindsay Morse

Walden Dissertations and Doctoral Studies

Food insecurity (FI) is a persistent public health challenge in the United States and disproportionately affects rural communities. Guided by syndemic theory, this quantitative cross-sectional study examined associations between FI and chronic disease outcomes among rural residents of Vermont and the Adirondack region of New York. Social determinants of health screenings and electronic medical records from 35 rural primary care sites were analyzed. Secondary data from n = 72,505 adults were used to evaluate these relationships. Binary logistic regression models assessed obesity, hypertension (HTN), and diabetes (DM), and a multinomial logistic regression model evaluated the combined presence of obesity and …

Polθ Activity Modulates Sensitivity To Standard Therapies In Dnmt3a-Deficient Leukemia, Bac Viet Le, Umeshkumar Vekariya, Monika M. Toma, Margaret Nieborowska-Skorska, Marie-Christine Caron, Malgorzata Gozdecka, Zayd Haydar, Martin Walsh, Jayashri Ghosh, Elaine Vaughan-Williams, Paulina Podszywalow-Bartnicka, Anna-Mariya Kukuyan, Sylwia Ziolkowska, Jessica Atkins, Emir Hadzijusufovic, Gurushankar Chandramouly, Reza Nejati, Katarzyna Piwocka, Richard T. Pomerantz, George S. Vassiliou, Brian J.P. Huntly, Peter Valent, Mariusz Wasik, Alfonso Bellacosa, Jean-Yves Masson, Gaorav P. Gupta, Grant A. Challen, Tomasz Skorski

Department of Biochemistry and Molecular Biology Faculty Papers

Myeloid malignancies carrying somatic DNMT3A mutations (DNMT3Amut) are refractory to standard therapy. DNMT3Amut leukemia cells accumulate toxic DNA double-strand breaks (DSBs) and stalled replication forks, rendering them dependent on DNA damage response (DDR). We report here that DNA polymerase theta (Polθ), a key element in DSB repair by end-joining (Polθ-mediated end-joining [TMEJ]) and in fork restarting, promotes survival and proliferation of DNMT3Amut leukemia cells. Polθ is overexpressed in DNMT3Amut leukemia cells due to abrogation of PARP1 PARylation-dependent UBE2O E3 ligase-mediated ubiquitination and proteasomal degradation of Polθ. In addition, PARP1-mediated recruitment of the SMARCAD1-MSH2/MSH3 repressive complex to DSBs is diminished in …

Weakening The Reasonable Efforts Requirement In New Mexico Termination Of Parental Rights Cases, Monika Myers

New Mexico Law Review

Parents’ right to control the upbringing of their own children is long-established in the United States. However, in the case of child abuse, neglect, or abandonment, a state can terminate parental rights, permanently severing the legal relationship between a parent and a child. In New Mexico, to terminate parental rights for abuse or neglect the State must prove three elements by clear and convincing evidence: (1) the child is abused or neglected; (2) the conditions that brought the child into care are unlikely to change in the foreseeable future and (3) this is the case despite reasonable efforts by the …

Tet Cpg Sequence-Context-Specific Dna Demethylation Shapes Progression Of Idh-Mutant Gliomas., Youri Hoogstrate, Santoesha A Ghisai, Levi Van Hijfte, Rania Head, Iris De Heer, Marta Padovan, Maurice De Wit, Wies R Vallentgoed, Angelo Dipasquale, Maarten M J Wijnenga, Bas Weenink, Rosa Luning, Sybren L N Maas, Adela Brzobohata, Michael Weller, Tobias Weiss, Maximilian J Mair, Anna S Berghoff, Adelheid Wöhrer, Albert Jeltsch, Johan A F Koekkoek, Hans M Hazelbag, Mathilde C M Kouwenhoven, Yongsoo Kim, Bart A Westerman, Bauke Ylstra, Anneke M Niers, Kevin C Johnson, Frederick S Varn, Roel G W Verhaak, Mustafa Khasraw, Martin J Van Den Bent, Pieter Wesseling, Pim J French

Faculty Research 2026

Treatment decisions in IDH-mutant oligodendrogliomas are shaped by tumor aggressiveness, underscoring the need for objective grading of these malignant brain tumors. We collect 302 primary and recurrent resections from oligodendrogliomas and perform Ki-67 staining, proteomics, and DNA methylation profiling. During tumor progression, DNA methylation of oligodendrogliomas changes along a continuum. This continuum is linked to increased epigenetic aging, methylation of transcription factors and Ki-67+ cell density, and large-scale DNA demethylation. Demethylation correlates with CpG flanking sequences preferred by TET enzymes. We confirm these findings in previously profiled astrocytomas, indicating IDH-mutant gliomas progress along a shared epigenetic axis. We develop an …

Rethinking Ratio-Based Normalization Towards Model-Based Approaches In Heart Weight Analysis., Manuela A Oestereicher, Patricia Da Silva-Buttkus, Valérie Gailus-Durner, Susan Marschall, Helmut Fuchs, Impc Consortium, Martin Hrabě De Angelis, Elida Schneltzer, Nadine Spielmann

Faculty Research 2026

Heart weight (HW) is a critical parameter in cardiology and mouse research, commonly normalized to body weight (BW) or tibia length (TL) to account for size differences. Ratio-based normalization, however, assumes strict proportionality between variables, an assumption that is rarely tested and may bias group comparisons. We analysed HW, BW, and TL measurements from over 25,000 C57BL/6N wildtype mice generated by the International Mouse Phenotyping Consortium. Sex- and age-stratified analyses were combined with simulation-based modelling to evaluate empirical scaling relationships and the statistical behaviour of ratio-based normalization. Across all age and sex groups, correlations between HW, BW, and TL were …

New Viability Assays For Acanthamoeba Castellanii Trophozoites And Cysts Allow Rapid Assessment Of Drug Activity., Carrie A Flynn, Rebecca I Colón-Ríos, Andrew Harmez, William F Flynn, Barbara I Kazmierczak

Faculty Research 2026

Pathogenic free-living amoebae such as Acanthamoeba castellanii are present in soil and water worldwide. A. castellanii causes systemic infections with very high mortality rates, yet drugs specifically targeting this pathogen are not available. Methods to reliably generate and assay cysts, which drive infection recurrence and drug resistance, are unavailable in a high-throughput format suitable for drug screening and testing. In this study, we developed a robust and reproducible protocol for encysting A. castellanii as well as a high-throughput, quantitative cyst viability assay using fluorescent live/dead staining coupled with microscopy and automated image analysis. These methods, coupled with optimized techniques for …

Tet Cpg Sequence-Context-Specific Dna Demethylation Shapes Progression Of Idh-Mutant Gliomas., Youri Hoogstrate, Santoesha A Ghisai, Levi Van Hijfte, Rania Head, Iris De Heer, Marta Padovan, Maurice De Wit, Wies R Vallentgoed, Angelo Dipasquale, Maarten M J Wijnenga, Bas Weenink, Rosa Luning, Sybren L N Maas, Adela Brzobohata, Michael Weller, Tobias Weiss, Maximilian J Mair, Anna S Berghoff, Adelheid Wöhrer, Albert Jeltsch, Johan A F Koekkoek, Hans M Hazelbag, Mathilde C M Kouwenhoven, Yongsoo Kim, Bart A Westerman, Bauke Ylstra, Anneke M Niers, Kevin C Johnson, Frederick S Varn, Roel G W Verhaak, Mustafa Khasraw, Martin J Van Den Bent, Pieter Wesseling, Pim J French

Faculty Research 2026

Treatment decisions in IDH-mutant oligodendrogliomas are shaped by tumor aggressiveness, underscoring the need for objective grading of these malignant brain tumors. We collect 302 primary and recurrent resections from oligodendrogliomas and perform Ki-67 staining, proteomics, and DNA methylation profiling. During tumor progression, DNA methylation of oligodendrogliomas changes along a continuum. This continuum is linked to increased epigenetic aging, methylation of transcription factors and Ki-67+ cell density, and large-scale DNA demethylation. Demethylation correlates with CpG flanking sequences preferred by TET enzymes. We confirm these findings in previously profiled astrocytomas, indicating IDH-mutant gliomas progress along a shared epigenetic axis. We develop an …

Using Mobile Devices To Support Outdoor Stem Learning In Rural Contexts: An Embedded Mixed-Methods Study, Jayson Seaman, Amanda Bastoni, Andrew D. Coppens, Cindy L. Hartman, Courtney Lachaine, Katelyn Moscouver, Janet Gronneberg

Faculty Publications

Background: Rural youth face barriers to involvement in effective Science, Technology, Engineering, and Math (STEM) learning experiences, leading to persistent underrepresentation in STEM fields. Purpose: This study examined the feasibility of using mobile devices to engage rural youth in informal STEM learning (ISL) during free-choice, outdoor recreational activities. We assessed outcomes of a 10-month intervention related to STEM interest, identity, and future planning. Method: Fifty-four youth ages 12 to 17 completed monthly STEM challenges delivered via a mobile platform, aligned with connected learning and free-choice learning principles. Surveys measured pre/post changes in STEM supports, STEM confidence, and …

New Viability Assays For Acanthamoeba Castellanii Trophozoites And Cysts Allow Rapid Assessment Of Drug Activity., Carrie A Flynn, Rebecca I Colón-Ríos, Andrew Harmez, William F Flynn, Barbara I Kazmierczak

Faculty Research 2026

Pathogenic free-living amoebae such as Acanthamoeba castellanii are present in soil and water worldwide. A. castellanii causes systemic infections with very high mortality rates, yet drugs specifically targeting this pathogen are not available. Methods to reliably generate and assay cysts, which drive infection recurrence and drug resistance, are unavailable in a high-throughput format suitable for drug screening and testing. In this study, we developed a robust and reproducible protocol for encysting A. castellanii as well as a high-throughput, quantitative cyst viability assay using fluorescent live/dead staining coupled with microscopy and automated image analysis. These methods, coupled with optimized techniques for …

Genomic Medicine In Pediatrics: What Pediatricians Need To Know Now, Michael Smith, Scott T. Younger

Pediatrics in Practice: A CME Podcast

Genomic medicine is playing an increasingly important role in pediatric care, but it can feel complex for general pediatricians. In this episode of Pediatrics in Practice, Scott Younger, PhD, discusses how genomics is already influencing pediatric diagnosis and care today, common scenarios where genetic insights may be helpful, and why genomic testing can be valuable even when it doesn’t lead to a targeted therapy. This conversation offers practical guidance on when to consider genomics, when to refer, and how pediatricians can partner with genetics and subspecialty teams to support patients and families.

Click here to stream the podcast episode.

The Journey Of The Soul In Aboriginal Australia, Ian S. Mcintosh

International Journal of Religious Tourism and Pilgrimage

For the past decade, I have been studying pilgrimage in all its dimensions in what my colleagues and I have been calling a kaleidoscopic inquiry (McIntosh et al., 2024). In my current investigations, I have been exploring the journey of the soul upon the death of its host. My focus in this working paper is the myths and traditions of the Yolngu Indigenous peoples of northeast Arnhemland in remote northern Australia with whom I lived and worked in the 1980s and 90s. The Yolngu go to great lengths to prepare the dying for their ultimate journey, painting the body with …

Remote Language Assessment In School-Age Children With Phelan–Mcdermid Syndrome And Genotype–Phenotype Correlation, Sarah Quadri-Valverde, Jessica Klusek Ph.D., Ccc-Slp, Linda D. Ward, Diana Ivankovic, Nancy Powers, Vijay Shankar, Rachel A. Lyman, Trudy F.C. Mackay, William Bridges, Katy Phelan, Chris Rogers, Luigi Boccuto, Sara M. Sarasua

Faculty Publications

People with Phelan–McDermid syndrome (PMS) have reduced speech and language abilities, yet little research has profiled the communication abilities in this population. The purpose of this study was threefold: identifying the language and communication profiles of school-aged children with PMS, identifying genetic contributions to language and communication abilities, and determining the feasibility of remote data collection for research purposes. A speech language pathologist used standardized assessments and direct evaluations by video conferencing to evaluate language and communication abilities. Sixteen children and adolescents were evaluated: 5 with SHANK3 pathogenic variants, 9 with 22q13 deletions including SHANK3 (PMS-SHANK3 related), and 2 …

Bicuspid Valve Closure And Backflow Prevention: Role Of Leaflet Geometry, Badr Kauoi, A Bou Orm, P Navet, James W. Baish, Lance Munn

Faculty Journal Articles

Bicuspid valves with crescent-shaped leaflets are found in lymphatic vessels and veins, where their primary function is to prevent reflux and ensure unidirectional flow toward the heart. These valves are passive, and their functionality emerges spontaneously from a complex interplay between the properties of the valve leaflets and the flow patterns developing within the vessel sinus region surrounding the valve. The main function of the valves is to limit retrograde flow, or reflux, but the optimal valve structure has not been well characterized. Here we investigate numerically how the length of the leaflets affects the valve efficiency in preventing reflux. …

Understanding Agtech Adoption: Evidence From The Farm Tech Adoption Challenge 2025, Ankit Chandra, Mark Stone

Department of Agricultural and Biological Systems Engineering: Presentations and White Papers

The Farm Tech Adoption Challenge (FTAC) examined how farmers evaluate emerging agricultural technologies through structured interactions with startups. Farmers assessed solutions based on their on-farm challenges and indicated adoption decisions. Results showed that adoption was driven by how well technologies addressed economic pressure, risk reduction, and operational simplicity. Startups aligned with these priorities were more likely to gain traction, with five out of nine receiving farmer commitments for adoption. However, adoption also depended on clear economic value, field validation, and system integration. Overall, the findings suggest that the primary bottleneck in agtech is not the lack of relevant technologies, but …

Biodeterrence In An Era Of Convergent Threats, James Giordano

Strategic Insights

This commentary examines the growing need for a comprehensive biodeterrence strategy in response to the convergence of biotechnology, artificial intelligence, and cross-domain warfare capabilities. Dr. Giordano argues that advances in life sciences, combined with the activities of peer competitors, are transforming the biological domain into a contested strategic space where biological effects intersect with other forms of warfare. Traditional biodefense approaches are no longer sufficient. Instead, this piece calls for an integrated biodeterrence framework that combines biosurveillance, intelligence, public health, and operational planning. Recommendations include developing a Department of War–wide biodeterrence strategy, expanding detection and attribution capabilities, strengthening biotechnology intelligence, …