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2025

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Fluorescence-Guided Resection Of Gl261 Red-Fluc And Trp-Mcherry-Fluc Mouse Glioblastoma Tumors, Louis T. Rodgers, Bryan J. Maloney, Anika M. S. Hartz, Björn Bauer Jan 2025

Fluorescence-Guided Resection Of Gl261 Red-Fluc And Trp-Mcherry-Fluc Mouse Glioblastoma Tumors, Louis T. Rodgers, Bryan J. Maloney, Anika M. S. Hartz, Björn Bauer

Pharmaceutical Sciences Faculty Publications

Background: Most preclinical studies on glioblastoma (GBM) fail to provide translational utility in the clinic. Fluorescence-guided surgery using 5-aminolevulinic acid (5-ALA) improves tumor resection, disease prognosis, and, thus, patient outcomes. Given the critical role of surgery in managing recurrent GBM, it is essential to incorporate surgical elements into preclinical models to accurately reflect clinical scenarios and enhance translational success. However, existing protocols for 5-ALA-guided resection in preclinical models are limited and often lack clinical relevance.

Methods: To address this gap, we developed a novel protocol for the 5-ALA-guided resection in two mouse GBM models: TRP-mCherry-FLuc and GL261 Red-FLuc.

Results: The …


Enhancing Topical Delivery Of N-Acetylcysteine And Collagen Via A Novel Electrospun Collagen/Pmma Nanofibrous Mats As Facial Mask Development: Nanofibers Optimization And In Vitro Experiments, Abdullah Elbadry, Elbadawy Kamoun, Mahmoud Sabahy, Mohamed Helmy, Mahmoud Khaled, Shahira Elmosalamy, Noura Eissa Jan 2025

Enhancing Topical Delivery Of N-Acetylcysteine And Collagen Via A Novel Electrospun Collagen/Pmma Nanofibrous Mats As Facial Mask Development: Nanofibers Optimization And In Vitro Experiments, Abdullah Elbadry, Elbadawy Kamoun, Mahmoud Sabahy, Mohamed Helmy, Mahmoud Khaled, Shahira Elmosalamy, Noura Eissa

Nanotechnology Research Centre

No abstract provided.


Academic Proficiency In Ugandan Children With Sickle Cell Anemia: A Cross-Sectional Study, Robert Opoka, Shubaya Kasule Naggayi, Paul Bangirana, Simple Ouma, Betty Nyangoma, Annet Birabwa, Grace Nambatya, Maxencia Kabatabaazi, Ann Jacqueline Nakitende, Dennis Kalibbala Jan 2025

Academic Proficiency In Ugandan Children With Sickle Cell Anemia: A Cross-Sectional Study, Robert Opoka, Shubaya Kasule Naggayi, Paul Bangirana, Simple Ouma, Betty Nyangoma, Annet Birabwa, Grace Nambatya, Maxencia Kabatabaazi, Ann Jacqueline Nakitende, Dennis Kalibbala

Paediatrics and Child Health, East Africa

Introduction: Academic proficiency is crucial for advancing learning goals, school advancement, and future economic security. Children with sickle cell anemia (SCA) in sub-Saharan Africa (SSA) may be at risk of disease-associated learning difficulties. Limited data exist on this topic among school-age children in the region. We aimed to assess academic proficiency in a sample of children with SCA in Uganda compared with unaffected controls.

Methods: This cross-sectional study was conducted in Kampala, Uganda. Participants were school-going children with SCA, aged 6–12 years, attending Mulago Hospital SCA Clinic, and age-matched sibling controls without SCA. Academic proficiency was assessed by the Wide …


Periconceptual Nutrition And The Preimplantation Embryo: Approaches For Intervention And Generational Health, Abigail Klein Jan 2025

Periconceptual Nutrition And The Preimplantation Embryo: Approaches For Intervention And Generational Health, Abigail Klein

Dissertations and Theses

The typical American diet exceeds dietary fat recommendations, contributing to the rising rates of obesity. This negatively impacts fertility, pregnancy and fetal growth, and lifelong offspring health. During pregnancy, this also increases risk of co-morbidities like gestational diabetes. Despite this, lipids are not screened during pregnancy and limited research exists evaluating these co-exposures on offspring health. Our lab used a rat model of maternal high fat (HF) diet with late-gestation diabetes (DM) to demonstrate that mitochondrial dysfunction and oxidative stress incite lifelong cardiometabolic disease risk in offspring. To determine the timing of damage, we hypothesized that maternal overnutrition incites mitochondrial …


Empowering Youth Aging Out Of Foster Care: A Needs Assessment To Improve Transitions To Independent Living, Parker Brady, Amy Six-Means, Julia Durante, Anubha Sood, Philip Day, Nora Gimpel, Jill Mcleigh, Kimberly Stone Jan 2025

Empowering Youth Aging Out Of Foster Care: A Needs Assessment To Improve Transitions To Independent Living, Parker Brady, Amy Six-Means, Julia Durante, Anubha Sood, Philip Day, Nora Gimpel, Jill Mcleigh, Kimberly Stone

Health Status, Outcomes, and Literacy and Healthcare Utilization

We aimed to assess the health literacy (HL) of youth transi- tioning out of foster care and how they interact with health information. The Newest Vital Signs survey was administered online to 26 youth who experi- enced foster care. Seven youth and 15 stakeholders also com- pleted focus groups discussing how youth handle health infor- mation. Results indicate that 42% of youth may have lim- ited HL, which places them at risk for poor health outcomes. Future studies should further characterize this population’s HL and study physician and technology-based interventions to address limited HL.

For questions about this study or …


Rethinking Social Rights From Latin America, Christian Gonzalez Chacon Jan 2025

Rethinking Social Rights From Latin America, Christian Gonzalez Chacon

Washington and Lee Journal of Civil Rights and Social Justice

International human rights courts and bodies have traditionally enforced social rights within constrained frameworks, such as “available resources” and “minimum provision,” often overlooking deeper structural inequalities and urgent global challenges. This paper advocates for a paradigm shift grounded in the capabilities framework, reconceptualizing rights to encompass sustainability, harmony, and human flourishing. Drawing on indigenous philosophies from Latin America, I propose strategies to strengthen enforcement mechanisms, including the establishment of specialized human rights courts, equitable taxation systems, and regenerative economic models. By aligning human rights with capabilities and ecological stewardship, this paper illustrates their potential to address poverty, inequality, and climate …


The Design Of A Bioinspired Impact Mitigation System Towards The Prevention Of Brain Injuries, Bryce H. Reimer Jan 2025

The Design Of A Bioinspired Impact Mitigation System Towards The Prevention Of Brain Injuries, Bryce H. Reimer

Master’s Theses

Traumatic brain injuries (TBIs), including concussions and chronic traumatic encephalopathy (CTE), remain a major concern across contact sports, military operations, and transportation. Despite advancements in protective equipment, current strategies often fall short in preventing the mechanical conditions that contribute to long-term neurological damage. This thesis presents the design and validation of a bioinspired impact mitigation system modeled after bighorn sheep horn structures, which have evolved to endure high-energy collisions without apparent brain injury.

Using biomimetic principles, the research integrates experimental and computational methods to evaluate how horn-like geometries reduce impact-induced accelerations. A custom drop tower was built to test dynamic …


Gestational Diabetes And Prenatal Care, Katie Do, Ysabelle Gardon, Stephanie Gripton, Phuong Ky, Joann Lee, Thy Tran Jan 2025

Gestational Diabetes And Prenatal Care, Katie Do, Ysabelle Gardon, Stephanie Gripton, Phuong Ky, Joann Lee, Thy Tran

Bachelor of Science in Nursing Senior Synthesis

No abstract provided.


Retrospective Cross-Sectional Analysis Of Glp-1 Receptor Agonist Effects On Outcomes Of Hemiarthroplasty For Femoral Neck Fractures In Diabetics, Mckenna W. Box, Troy Puga, Neil Werthmann, Yingxian Liu, John T. Riehl Jan 2025

Retrospective Cross-Sectional Analysis Of Glp-1 Receptor Agonist Effects On Outcomes Of Hemiarthroplasty For Femoral Neck Fractures In Diabetics, Mckenna W. Box, Troy Puga, Neil Werthmann, Yingxian Liu, John T. Riehl

North Texas Research Forum 2025

Introduction: To determine if the use of glucagon-like peptide-1 receptor agonists (GLP-1RA) in type 2 diabetic mellitus (T2DM) patients affects outcomes after hemiarthroplasty for femoral neck fractures (FNFs). Methods: A retrospective cross-sectional analysis of a local hospital system database was performed using Current Procedural Terminology (CPT) and International Classification of Diseases (ICD-10) codes to identify T2DM patients who were at least 18 years of age who underwent hemiarthroplasty (HA) for FNFs and were on a GLP-1RA at the time of injury. A random patient sample of those who underwent HA and were not on a GLP-1RA was used as a …


Severe Hypercalcemia In A Patient Taking Chronic Shark Fin Supplements, Sumanth Reddy, Bishwas Upadhyay Jan 2025

Severe Hypercalcemia In A Patient Taking Chronic Shark Fin Supplements, Sumanth Reddy, Bishwas Upadhyay

North Texas Research Forum 2025

BACKGROUND/INTRODUCTION: In this study, we discuss a case of an 86 year old Vietnamese female who presents with severe hypercalcemia, 15.0, who presented with progressively worsening physical debility which resulted in the patient being wheelchair bound after being found to be taking chronic calcium supplements. Hypercalcemia is a metabolic abnormality that is known to cause muscle weakness, changes in sensorium, dehydrations, nausea, anorexia, polyuria, constipation, fatigue, and depression. CASE PRESENTATION: Patient is an 85 year old female with significant medical history of osteoarthritis who presented to the emergency department for generalized fatigue for the past 2 weeks. Patient reports that …


A Rare Case Of Prolonged Life Expectancy In A Patient With Duchenne Muscular Dystrophy, Sara Shahid, Mina Choudhry, Anam Zara Jan 2025

A Rare Case Of Prolonged Life Expectancy In A Patient With Duchenne Muscular Dystrophy, Sara Shahid, Mina Choudhry, Anam Zara

Gulf Coast Division GME Research Day 2025

No abstract provided.


Breaking The Blockade: A Retrospective Analysis Of Pediatricconstipation In Hospitalized Patients, Yenamala Reddy, Jaicy Pottokaran, Eric K. Shaw, Aimee Behnke, Jean B. Wiggins, Lauren Hebert, Norman Taylor Parks Jan 2025

Breaking The Blockade: A Retrospective Analysis Of Pediatricconstipation In Hospitalized Patients, Yenamala Reddy, Jaicy Pottokaran, Eric K. Shaw, Aimee Behnke, Jean B. Wiggins, Lauren Hebert, Norman Taylor Parks

South Atlantic Division GME Research Day 2025

No abstract provided.


Severe Right Ventricular Dilation Due To Selenium Deficiency In A Post Gastric Bypass Patient - A Rare But Life Threatening Complication, Arjun Kamath, Jorge Garza, Ethan Goldberg, A Syed, Deekshita Valiveti, Abhay Vakil, Zuhair Ali, A Ashgar, Luay Alalawi, Heriberto Cantu, Thomas Alexander Jan 2025

Severe Right Ventricular Dilation Due To Selenium Deficiency In A Post Gastric Bypass Patient - A Rare But Life Threatening Complication, Arjun Kamath, Jorge Garza, Ethan Goldberg, A Syed, Deekshita Valiveti, Abhay Vakil, Zuhair Ali, A Ashgar, Luay Alalawi, Heriberto Cantu, Thomas Alexander

Gulf Coast Division GME Research Day 2025

No abstract provided.


Hypothyroidism Associated Hyponatremia, A Complicated Presentation, Gary Lee, Spencer Steinberg, Samiuallh Shahid, Evangelista Ezenduka, Edgardo Flores Jan 2025

Hypothyroidism Associated Hyponatremia, A Complicated Presentation, Gary Lee, Spencer Steinberg, Samiuallh Shahid, Evangelista Ezenduka, Edgardo Flores

North Texas Research Forum 2025

Introduction: Hypothyroidism is a well known text-book cause of euvolumic hyponatremia that is a rare occurrence in clinical practice in the absence of other potential etiologies of hyponatremia. We review a case of a 48 year old female presenting with profound generalized weakness found to have severe hyponatremia, later found to have severe hypothyroidism during admission. We review the potential mechanisms whereby hypothyroidism results in hyponatremia and whether or not hypothyroidism-induced hyponatremia truly exists and the current evidence supporting these views Case Presentation: 48 year old female with history of hypothyroidism, breast cancer post right lumpectomy and radiation presented for …


Treatment Of Starvation Ketoacidosis In The Third Trimester Of Pregnancy: A Case Report, Christine Le, Charmaine Oladell, Nicole Tenzel Jan 2025

Treatment Of Starvation Ketoacidosis In The Third Trimester Of Pregnancy: A Case Report, Christine Le, Charmaine Oladell, Nicole Tenzel

North Texas Research Forum 2025

INTRODUCTION: Starvation ketoacidosis represents a rare but complicated maternal morbidity that primarily occurs in the third trimester of pregnancy. With increased insulin resistance and metabolism manifesting in pregnancy, prompt care is required to diagnose and treat starvation ketoacidosis as it appears at an accelerated rate. However, despite the severity of maternal and fetal complications arising from this condition, standardized treatment protocols have not been elucidated. CASE PRESENTATION: In this case report, a 33-year-old gravida 3 para 0-2-0-2 at 31 weeks and 5 days gestational age was admitted to antepartum services for intractable nausea, vomiting, and anuria and transferred to the …


The Constitutional Gray Area Of Physician-Assisted Suicide: Implications In A Post Dobbs Society, Christina Chatrnuck Jan 2025

The Constitutional Gray Area Of Physician-Assisted Suicide: Implications In A Post Dobbs Society, Christina Chatrnuck

Student Works

No abstract provided.


Turmeric, Red Yeast Paste, And Statins: A Recipe For Dili, John V. Nahas, Sinay Ceballos, Franklin Kasmin Jan 2025

Turmeric, Red Yeast Paste, And Statins: A Recipe For Dili, John V. Nahas, Sinay Ceballos, Franklin Kasmin

East Florida Division GME Research Day 2025

Introduction Drug induced liver injury (DILI) contributes to a significant portion of acute liver injuries and acute liver failure in the west. DILI accounts for approximately 11% of acute liver failure cases in the US according to ACG. Insulting agents are numerous and well documented in the NIH LiverTox database, however the rarity and complexity of individual agents is a matter of ongoing study. Case Description/Methods A 52 year old man with PMH of HTN and HLD presents for a 2 week history of abdominal swelling, bilateral lower extremity swelling, decreased appetite, and positional shortness of breath. He endorses occasionally …


Insurance Law, J. Price Collins, Janet Tolbert, Ashley F. Gilmore Jan 2025

Insurance Law, J. Price Collins, Janet Tolbert, Ashley F. Gilmore

SMU Annual Texas Survey

This Article describes and analyzes major developments in insurance law that occurred in Texas between December 1, 2023, and November 30, 2024.


The Impacts Of Ssris In-Utero And Nicu Occupational Therapy Intervention, Kyara Crowley Jan 2025

The Impacts Of Ssris In-Utero And Nicu Occupational Therapy Intervention, Kyara Crowley

Occupational Therapy Capstones

Purpose: The purpose of this product was to collaborate with the occupational therapy (OT) staff in a neonatal intensive care unit (NICU) to further knowledge and enhance role competence to provide better quality of care to the selective serotonin reuptake inhibitor (SSRI) exposed infant population. Mental health conditions are becoming more prevalent among women, therefore, more women are taking SSRIs throughout pregnancy to counteract the effects of those conditions (Cleveland Clinic, 2024). However, the effects of in-utero SSRI exposure are not fully understood. Researchers have found evidence of some short-term and long-term effects caused by the SSRI exposure as well …


Buying Green On A Student Budget: How Sustainability Shapes Gen-Z Grocery Habits, Tyler Martin, Diane R. Edmondson, Lucy Matthews Jan 2025

Buying Green On A Student Budget: How Sustainability Shapes Gen-Z Grocery Habits, Tyler Martin, Diane R. Edmondson, Lucy Matthews

Atlantic Marketing Journal

Sustainability is increasingly prioritized by consumers, but concerns arise about whether Gen-Z college students with limited financial means translate sustainable attitudes into purchasing behaviors. This study surveyed 496 undergraduate students at a southeastern public university to assess attitudes, motivations, and actions regarding sustainable grocery shopping. Results reveal strong environmental concerns among students but a notable gap between beliefs and purchasing behaviors, attributed mainly to financial constraints. Gender, political affiliation, and religious affiliation significantly influenced sustainable behavior. Managerial implications and future research directions are discussed.


Omnichannel Retailing: An Exploratory Study Of Limiting The Customer Journey In A Digital-First Context, Terence L. Holmes, Edward C. Brewer, Elizabeth Patterson Jan 2025

Omnichannel Retailing: An Exploratory Study Of Limiting The Customer Journey In A Digital-First Context, Terence L. Holmes, Edward C. Brewer, Elizabeth Patterson

Atlantic Marketing Journal

A recent retail trend is the rise of “digital-first” firms, where their merchandise is sold primarily via online efforts. In this exploratory study we describe our investigation of the customer journey for a digital-first seller of cosmetics and personal care products. We collected qualitative and quantitative data from a customer survey and follow-up interviews. Results indicate that personal connections and actual product use are the two most important touchpoints customers consider in first discovering the seller and then building a relationship with the brand. We describe practical applications of the findings and suggest ideas for future research.


Regulating The Forever Wild, Edward W. De Barbieri Jan 2025

Regulating The Forever Wild, Edward W. De Barbieri

SMU Law Review

Communities in rural areas regularly come into conflict with government bodies regarding the use of protected lands. From New York, to Alaska, to Nevada—and many places in between—a common question emerges: who should have authority to regulate human activity on and around wilderness lands? It is not a new phenomenon for urban dwellers, often controlling money and political power, to use influence and a specter of conservation to control what is permitted in rural spaces. Resulting unrest among rural resi­dents may be the result of the exclusion of poor, racially underrepresented, indigenous, and other residents who earn their livelihood from …


Availability And Use Of Digital Technology Among Women With Polycystic Ovary Syndrome: Scoping Review, Pamela J. Wright Phd, Ms, Med, Rn, Cen, Charlotte Burts, Carolyn Harmon, Cynthia F. Corbett Phd, Rn, Faan Jan 2025

Availability And Use Of Digital Technology Among Women With Polycystic Ovary Syndrome: Scoping Review, Pamela J. Wright Phd, Ms, Med, Rn, Cen, Charlotte Burts, Carolyn Harmon, Cynthia F. Corbett Phd, Rn, Faan

Publications

Background: Polycystic ovary syndrome (PCOS) is a common endocrinopathy among women that requires self-management to improve mental and physical health outcomes and reduce risk of comorbidity. Digital technology has rapidly emerged as a valuable self-management tool for people with chronic health conditions. However, little is known about the digital technology available for and used by women with PCOS. Objective: The purpose of this scoping review was to identify what is known about digital technology currently available and used by women with PCOS for PCOS-specific knowledge, self-management, or social support. Methods: The databases PubMed, Embase, CINAHL, and Compendex were searched using …


Development Of A Stable Isotope Method To Measure Protein Fractional Synthesis Rate In Equine Skeletal Muscle, Antoinette E. Foliart Jan 2025

Development Of A Stable Isotope Method To Measure Protein Fractional Synthesis Rate In Equine Skeletal Muscle, Antoinette E. Foliart

Theses and Dissertations--Animal and Food Sciences

Muscle mass is regulated by the balance between muscle protein synthesis and degradation. Previous research in horses has shown that the signaling pathway that regulates protein synthesis is upregulated with increasing protein intake; however, whether this corresponds to an increase in muscle protein synthesis rates had not been previously explored. The objective of this study was to develop an isotopic method to measure muscle protein fractional synthesis rate (FSR) in horses following graded protein intake. Eight mature Thoroughbred horses were studied using a randomized cross-over design. Horses consumed meals containing 0 (No), 0.125 (Low), 0.25 (Med), or 0.5 (High) g …


Property Law— Squaring The Mold Predicament With Arkansas Landlord-Tenant Law, Katherine James Clark Jan 2025

Property Law— Squaring The Mold Predicament With Arkansas Landlord-Tenant Law, Katherine James Clark

University of Arkansas at Little Rock Law Review

No abstract provided.


Fy 2024 Categorical Eligibility By State, Andrew Hammond Jan 2025

Fy 2024 Categorical Eligibility By State, Andrew Hammond

Datasets by Maurer Faculty

No abstract provided.


Impact Of Maternal Chronic Diseases In Pregnancy On Duration Of Infant Intake Of Breastmilk In The Postpartum Period, Danielle Nicole Lodge Jan 2025

Impact Of Maternal Chronic Diseases In Pregnancy On Duration Of Infant Intake Of Breastmilk In The Postpartum Period, Danielle Nicole Lodge

Public Health Theses

Background: Chronic disease in pregnancy, including hypertensive disease, diabetes, and mental health disorders, is associated with adverse mother and infant health outcomes. Breastfeeding offers well-documented benefits, but currently, little evidence exists on how maternal chronic disease impacts the duration of breastfeeding postpartum, especially multiple chronic disease diagnoses. Objectives: To examine associations between maternal chronic disease and (1) duration of any breastmilk feeding through six months postpartum, (2) in-hospital infant feeding patterns, and (3) the impact of in-hospital breastmilk exposure on postpartum duration of breastmilk feeding among women with a chronic disease. Methods: This retrospective cohort study analyzed 1,294 maternal-infant records …


Subsidized And Forgotten: The Quiet Erosion Of The Supplemental Security Income Program In American Social Policy, Johntrell Bowles Jan 2025

Subsidized And Forgotten: The Quiet Erosion Of The Supplemental Security Income Program In American Social Policy, Johntrell Bowles

Public Health Theses

The Supplemental Security Income (SSI) program was created to guarantee a basic level of income security for the nation's most economically vulnerable populations: low-income elderly adults, people who are blind, and individuals with disabilities. Despite this foundational mission, SSI has stagnated over the past fifty years, becoming increasingly inadequate in addressing the economic and social realities of those it was designed to support.

This thesis examines how congressional neglect, enduring stigma toward welfare recipients, and outdated policy structures have eroded SSI’s ability to fulfill its original promise. Grounded in a critical social policy framework and informed by the author's professional …


From Soil To Society: Enhancing Local Food Systems Through Global And Cultural Insights, Rhiannon Marie Morgan Jan 2025

From Soil To Society: Enhancing Local Food Systems Through Global And Cultural Insights, Rhiannon Marie Morgan

Undergraduate Theses, Professional Papers, and Capstone Artifacts

No abstract provided.


Navigating Food Justice: Addressing Student Food Insecurity Challenges And Successes, Jayden F. Beed Jan 2025

Navigating Food Justice: Addressing Student Food Insecurity Challenges And Successes, Jayden F. Beed

Undergraduate Theses, Professional Papers, and Capstone Artifacts

Food insecurity is a huge and often ignored wicked problem affecting college students across the United States. This capstone project explores the issue through the lens of food justice, which focuses on equitable access to nutritious food regardless of socioeconomic status or cultural background. Using the University of Montana Davidson Honors College as a case study, the project investigates student food insecurity, identifies systemic barriers, and outlines actionable strategies for addressing the issue on college campuses. At the center of this project is the creation of the UM Honors Food Pantry, developed by Jayden Beed in collaboration with the Davidson …