Digital Commons Network^™

M6a Rna Methylation In Psychiatric Disorders: An Emerging Epitranscriptomic Axis, Ambrose Loc Ngo, Linda Nguyen, Niki Gharavi Alkhansari, Huiping Zhang

Student Publications

N⁶-methyladenosine (m⁶A) is the most prevalent internal modification in eukaryotic messenger RNA (mRNA) and plays a vital role in post-transcriptional gene regulation. In recent years, m⁶A has emerged as a pivotal epitranscriptomic signal involved in neural development, synaptic remodeling, and the molecular pathophysiology of neuropsychiatric disorders. In this review, we summarize the mechanisms underlying the deposition, removal, and recognition of m⁶A by dedicated methyltransferases, demethylases, and RNA-binding proteins. We further explore how these dynamic modifications influence neuronal differentiation and memory formation. Recent studies have linked aberrant m⁶A regulation to psychiatric …

Pollen Loads Of Insects Caught In Cultivated Fields Of Oilseed Pennycress, Frank Forcella, Ellinor Sheik, Michael Zavada, Mark Bernards

The Great Lakes Entomologist

Although many insects are known to be associated with the floral canopies of oilseed pennycress (Thlaspi arvense), those that carry the crop’s pollen are unknown. During early spring of 2024 insects associated with pennycress flowers in Illinois and Minnesota were captured in sweep nets, frozen, sorted by species, and sonicated to remove pollen. Pollen grains were counted, and pollen loads per individual insect were calculated. Members of the orders Diptera, Hemiptera, and Hymenoptera accounted for 66%, 16%, and 14% of the 850 insects examined, but these same orders were responsible, respectively, for 18%, 3%, and 78% of the …

Community Building In Group Antenatal Care: A Scoping Review And Conceptual Framework, Anne Batchelder, Celeste Chavez, Ashley Gresh, Hayden Geibel, Crystal Patil, Nancy Glass

International Nursing Research Congress (INRC)

In US-based studies, group antenatal care (GANC) is associated with lower risk for prematurity and low birth weight and improved mental health; and resulted in higher satisfaction with care for clients and providers.^1,2 Evidence from recent clinical trials globally found that GANC improve key outcomes, including facility birth, antenatal and postpartum care attendance, quality of care, breastfeeding, and health literacy.^3–8 In GANC, cohorts of 8-12 pregnant clients attend their ANC visits together. Centering-inspired GANC models adhere to three core components: healthcare in a group space, interactive learning, and community building.^8–10 However, community building is poorly understood.

The …

Housing Challenges Affecting Well-Being Of Migrant Families In Canada: A Qualitative Study, Shela Hirani

International Nursing Research Congress (INRC)

Introduction: Immigrant and refugee families are vulnerable to cultural stereotyping and socioeconomic hardships when they migrate to a new country. Immigrants and refugees make up around 22.3% of the Canadian population. New immigrants and refugees face unique barriers that render them vulnerable to inadequate and unsafe housing conditions. Access to adequate and affordable housing has been strongly linked with all aspects of health and well-being amongst immigrants and refugee populations. There are significant knowledge gaps and limited empirical studies on the housing challenges of immigrant and refugee families, specifically in the province of Saskatchewan which has a noticeable increase in …

Integrating Community Partners Into Population Health Projects, Jaclyn Portanova, Jordan Ferris, Morgan A. Torris-Hedlund

International Nursing Research Congress (INRC)

The Population Health Project (PHP) provides an innovative approach for nursing baccalaureate students to develop policy and advocacy skills through immersive community engagement (Beiers-Jones et al., 2023). This case study highlights a community-academic partnership (CAP) between the African Youth & Community Organization (AYCO) and nursing students to address health inequities among refugees in Portland, Oregon. The purpose of this case study is to demonstrate how sustained CAPs like this can serve as a model for student-led public health initiatives.

Each term, nursing students collaborate with AYCO to identify and address specific health needs in the refugee population. A recent example …

Ready, Willing But Not Enabled: Families’ Perspectives On Participation In Early Mobilisation In Icu, Turkiah Saeed Alahmari, Peta Drury, John Rihari-Thomas, Yaseen Arabi, Bronwyn Everett

International Nursing Research Congress (INRC)

Introduction: Family participation in healthcare improves care quality and patient health outcomes (Price et al., 2022). It redirects family psychological distress into an active participatory role, humanising the patient's illness and recovery experience (Van Delft et al., 2021). Studies have focused on family participation in medical rounds, nutritional care, delirium assessment, and physical care of ICU patients (Goldfarb et al., 2023). Early mobilisation is advised for restoring functional ability, but patient-related issues, staffing shortages, and budget limitations may prevent its use in ICU settings (Bakhru et al., 2016). Current approaches to facilitate early mobility can be time-consuming, increase nurse burden, …

Factors Predicting Possible Sarcopenia In Community-Dwelling Older Adults, Wasana Srisuk, Noppawan Piaseu, Sukanya Tantiprasoplap

International Nursing Research Congress (INRC)

Possible sarcopenia, introduced by the Asian Working Group for Sarcopenia (AWGS) in 2019, is a guideline for early detection of sarcopenia in older adults living in the community. There is limited research on the prevalence of possible sarcopenia and its associated factors. This study aims to describe the prevalence of possible sarcopenia and identify its predictive factors in community-dwelling older adults.

This descriptive study included 117 community-dwelling older adults in Bangkok, Thailand, who were selected through stratified random sampling. Case finding and possible sarcopenia were assessed according to the AWGS guidelines. Descriptive statistics were used to determine the prevalence of …

Hfd Feeding For Seven Months Abolishes Sting Disruption-Driven But Not Female Sex-Based Protection Against Hepatic Steatosis And Inflammation In Mice, Xinlei Guo, Honggui Li, Bilian Zhu, Xiaoxiao Wang, Qian Xu, Eduardo A. Aquino, Minji Koo, Qingsheng Li, James Cai, Shannon Glaser, Chaodong Wu

Research Colloquium

Stimulator of interferon genes (STING) is positively correlated with the degrees of liver inflammation in human metabolic dysfunction-associated steatotic liver disease (MASLD). In addition, STING disruption alleviates MASLD in mice fed a high-fat diet (HFD) for 3 months (3- m-HFD). Here we investigated the role of the duration of dietary feeding in regulating MASLD in mice and explored the involvement of STING in sex differences in MASLD. Both male and female STING-disrupted (STINGgt) and wild-type C57BL/6J mice were fed an HFD for 3 or 7 months (7-m-HFD). Additionally, female STINGgt mice upon ovariectomy (OVX) and 3-m-HFD were analyzed for MASLD. …

Effects And Risks Of Pediatric Malnutrition On Neurodevelopmental Disorders And Cognitive Decline, Aminata A. Thiam, Ana M. Beatriz, Katie-Linn Poindexter, Mandy Jiang, Maxx Struhs, Valerie Vargas Ardila

OneUSF Undergraduate Research Conference

Malnutrition during early childhood is a significant risk factor for neurodevelopmental disorders (NDD) and cognitive decline (CD), with lasting effects into adulthood. Deficiencies in essential nutrients, such as vitamins, minerals, and fatty acids, hinder the proper development of the brain, leading to issues such as attention deficits, cognitive delays, and neurological disabilities. This project aims to examine the effects of pediatric malnutrition on neurodevelopmental outcomes and assess the metrics used to analyze cognitive outcomes in pediatric patients. Utilizing electronic databases such as PubMed and JAMA Network, a systematic literature review was conducted to evaluate the impact of CD and NDD …

Molecular Analysis And Biochemical Profiling Of Bacteria From Domestics Dogs Saliva: A Pilot Study, Hadba Al-Amrah, Asseel Alotiby, Badriyah Aljuhani, Hadeel Huri, Noha Al Garni, Reem Aljedani, Zeina W. Sharawi

The Journal of King Abdulaziz University: Science

Microbiota is the collection of microorganisms living in a particular environment, such as the dog’s saliva. The aim of the present work was the detection of bacteriome that plays a crucial role in various ecological processes and has a significant impact on the health and functioning of their host organisms. We collected saliva samples from five dogs. After that, identify the unknown bacterial species by inoculating samples into the Swapped Mannitol Salt Agar (MSA) and MacConkey (MAC). In addition, These bacterial isolates were identified by using morphological characteristics, biochemical tests, and partial sequencing of their 16S rRNA gene.Results] appeared in …

Gc Minutes Sept 18, 2025, Graduate Council

Graduate Council Minutes

No abstract provided.

Integrated Mirna-Mrna Analyses Of Triple-Negative Breast Cancer In Black And White Patients With Or Without Obesity, Fokhrul Hossain, Martha I. Gonzalez-Ramirez, Jone Garai, Diana Polania-Villanueva, Li Li, Farzeen Nafees, Md Manirujjaman, Bolin Liu, Samarpan Majumder, Xiao Cheng Wu, Chindo Hicks, Luis Del Valle, Denise Danos, Augusto Ochoa, Lucio Miele, Jovanny Zabaleta

School of Graduate Studies Faculty Publications

Triple-negative breast cancer (TNBC) is an aggressive, heterogeneous subtype of breast cancer. miRNAs play an essential role in TNBC pathogenesis and prognosis. Obesity is linked with an increased risk for several cancers, including breast cancer. Obesity is also related to the dysregulation of miRNA expression in adipose tissues. However, there is limited knowledge about race- and obesity-specific differential miRNA expression in TNBC. We performed miRNA sequencing of 48 samples (24 tumor and 24 adjacent non-tumor tissues) and RNA sequencing of 24 tumors samples from Black (AA) and White (EA) TNBC patients with or without obesity. We identified 55 miRNAs exclusively …

Sensory And Chemical Characterization Of Upcycled Pomace- And Whey-Based Piquette Beverages, Dean G. Hauser, Rahul Sen, Scott R. Lafontaine, Chris Gerling, Luann M. Preston-Wisley, Timothy A. Demarsh, Samuel D. Alcaine

Food Science Faculty Publications and Presentations

Upcycling, or utilizing materials that would otherwise go to waste, enables the creation of novel products that offer sustainability advantages and generate additional value. This study evaluates the feasibility of producing alcoholic beverages using yogurt acid whey (YAW) and grape pomace (GP), byproducts of the dairy and wine industries, respectively, and compares them to commercial grape pomace beverages (piquettes) in terms of sensory attributes and chemical composition. Two YAW-GP piquettes were produced, and five commercial piquettes were obtained. Sugars and organic acids were quantified using HPLC-RID, and semi-quantitative volatile composition was determined using HS-SPME-GC-MS/MS. Descriptive analysis was conducted using a …

Differential Effects Of Macrophage Subtype-Specific Cytokines On Fibroblast Proliferation And Endothelial Cell Function In Co-Culture System, Phillip Mcclellan, Thomas R. Wong, Sara Hijaz, David R. Fletcher, Ozan Akkus, Tracey L. Bonfield, James M. Anderson, Adonis Hijaz

Faculty Scholarship

Macrophages are involved in several critical activities associated with tissue repair and regeneration. Current approaches in regenerative medicine are focusing on leveraging the innate immune response to accelerate tissue regeneration and improve long-term healing outcomes. Of particular interest in this regard are the currently known, four main M2 macrophage subtypes: M2interleukin (IL)-4,IL-13, M2IC, M2IL-10, M2non-selective adenosine receptor agonists (NECA) (M2IL-4,IL-13 → M2(NECA). In this study, rat bone marrow-derived macrophages (M₀) were polarized to each of the four subtypes M2IL-4,IL-13 → M2NECA and cultured for 72 h in vitro. Luminex assay results highlighted increased production of tissue inhibitor of metalloproteinases-1 (TIMP-1) …

Abnormal Invasive Hemodynamics In Heart Transplant Recipients, Navin Rajagopalan, Donna R. Dennis, Julia Akhtarekhavari, Kenneth Campbell

Physiology Faculty Publications

BACKGROUND Few studies have quantified invasive hemodynamic parameters in post heart transplant recipients. AIM To report the incidence of abnormal hemodynamics in heart transplant recipients at 1-year and 3-year post-transplant and determine if there was any correlation with recipient and donor characteristics. METHODS Data from 279 consecutive heart transplant recipients from 2007 through 2020 were analyzed. Clinical variables regarding both recipients and donors as well as hemodynamic variables obtained via right heart catheterization during 1-year and 3-year annual testing were recorded. Simple and multiple linear regression tests were used to determine how recipient and donor variables influenced hemodynamic parameters at …

2025 September 18 - From My Notepads Newsletter, Office Of The President, East Tennessee State University, Brian Noland

From My Notepads: A Newsletter from President Brian Noland

No abstract provided.

The Cowl - V. 89 N. 1 - September 18, 2025

The Cowl

The Cowl - student newspaper of Providence College. Vol. 89 No. 1 - September 18, 2025. 20 pages.

Spartan Daily, September 18, 2025, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2025

Volume 165, Issue 12

Addressing Food System Determinants Of Health Inequalities In Urban Environments:: Learnings From The Foodsequal And Foodsequal-Health Projects, Carol Wagstaff, Clare Pettinger

School of Health Professions

Diet is just one social determinant of health, with obesity and diet-related illness as leading causes of premature deaths and disability in the UK. People living in deprived areas of the UK are more likely to experience poor health outcomes, linked to many social determinants of health such as diet, housing, employment, education, power and discrimination and psycho-social factors such as isolation, quality of social network and perceived level of control. While socio-economic deprivation is a key risk for health inequalities, protected characteristics, vulnerable groups and geographical factors also indicate populations at risk of experiencing health inequalities. In this ‘opinion …

Gc-Ms-Based Metabolomics For Understanding The Metabolite Profile Of Mopane Worm (Gonimbrasia Belina) And Sorghum (Sorghum Bicolor L), Mpho Sebabiki Maleke, Tumisi Beiri Jeremiah Molelekoa, Jonathan Wilkin, Xi Feng, Moira Ledbetter, Oluwafemi Ayodeji Adebo

Faculty Research, Scholarly, and Creative Activity

Edible insects are nutritious, having high levels of protein, essential amino acids, healthy fats, vitamins, and minerals. In areas where sorghum is a primary crop, mixing this gluten-free grain with protein-rich insect powder provides a novel approach to making nutrient-rich products. Understanding the sorghum and mopane worm flours' metabolomic changes during bioprocessing can however, enhance their nutritional value and food safety. The research investigated metabolite compounds that are found in raw and processed (fermented, malted (sorghum), and ultrasonicated) mopane worms and sorghum. In the study, sorghum grains were traditionally fermented and malted at 35°C for 48 h and ultrasonicated for …

The Economic Burden Of Covid-19 In A Region With Stringent Response Measures: A Case Study Of Taiwan, Elise Chia-Hui Tan, Fei-Yuan Hsiao, Ming-Chin Yang

Journal of Food and Drug Analysis

The COVID-19 pandemic has imposed a significant economic burden globally, particularly in regions with stringentresponse measures. This study aimed to assess the economic impact of COVID-19 in Taiwan, focusing on both directand indirect costs. A cost-of-illness analysis was conducted, utilizing data from the Taiwan Centers for Disease Control(CDC), national databases, epidemiological studies, and economic surveys. The analysis included both direct costs (e.g.,hospital admissions, outpatient care) and indirect costs (e.g., productivity losses due to long COVID, absenteeism, caregiving duties). The study encompassed Taiwan's population of 23.2 million, with particular attention to age-specific impacts on economic outcomes. The total economic burden of …

Global Research Trends On Avocado Oil And Its Fatty Acid Composition: A Bibliometric Review, Ahmad Kamrullah Aras, Abdul Rohman

Journal of Food and Drug Analysis

The high content of unsaturated fatty acids in avocado oil (Persea americana) has prompted in-depth exploration across research subjects. This study uses bibliometric analysis to assess global research trends on avocado oil and its fatty acid composition from 2004 to 2024. The search string retrieved 255 articles from the Scopus database and then analyzed using R BibliometriX and VOSviewer software. These tools analyze descriptive structures and collaborative patterns and create network data maps. For comparison, we separated the data into two research periods, namely 2004-2013 and 2014-2024. There was a significant increase in the number of publications, with …

Obesity Severity And Cancer Screening In Us Adults, Florina Corpodean, Michael Kachmar, Shengping Yang, Michael W. Cook, Philip R. Schauer, Vance L. Albaugh

School of Medicine Faculty Publications

No abstract provided.

Predictors Of All-Cause In-Hospital Mortality In Patients With Malignant Well-Differentiated Gastroenteropancreatic Neuroendocrine Tumors, Elvis Obomanu, Tarfa Verinumbe, Tinsae Anebo, Colton Jones, Claudia Dourado

Einstein Health Papers

BACKGROUND: Factors influencing in-hospital mortality in patients with well-differentiated gastroenteropancreatic neuroendocrine tumors (GEP-NETs) remain understudied, highlighting gaps in optimizing acute clinical outcomes. This study aimed to identify sociodemographic and clinical predictors of all-cause in-hospital mortality in this population.

METHODS: Using 2016 - 2020 data from the National Inpatient Sample (NIS), patients with malignant well-differentiated GEP-NETs were identified via the International Classification of Diseases, 10th Revision (ICD-10) codes. The primary outcome was in-hospital mortality. Sociodemographic and clinical variables (heart failure (HF), malnutrition, Charlson Comorbidity Index (CCI), and tumor site) were analyzed using multivariable logistic regression.

RESULTS: Among 5,642 patients (mean age …

Nanotechnology In Wastewater Treatment: Efficiency Review, Cost Analysis, And Reusing, Shuokr Qarani Aziz, Sarwah Othman Ismael, Khalat Khalid Muhammad Salih

Polytechnic Journal

The increasing worldwide water shortage demands the immediate implementation of advanced, sustainable wastewater treatment solutions. Nanotechnology provides promising options through nanomaterials, including metal oxides, magnetic nanoparticles (MNPs), and carbon-based composites, which show high removal efficiencies of 50–98% for organic contaminants and 80–99% for inorganic pollutants. This review analyzes various nanomaterials used in wastewater treatment by examining their functional mechanisms, including adsorption, catalytic degradation, and membrane-based separation, and assesses their performance relative to traditional methods. It addresses the major barriers to large-scale implementation, including high production expenses, ecological dangers, and scalability problems. The paper stresses the necessity of interdisciplinary collaboration between …

Effect Of Vitamin D Supplementation During Pregnancy And Lactation On The Development Of Infants Born To Tanzanian Women Living With Hiv: A Secondary Analysis Of A Randomised Controlled Trial, Temiwunmi Shobanke, Alfa Muhihi, Nandita Perumal Phd, Nzovu Ulenga, Fadhlun M. Alwy Al-Beity, Christopher P. Duggan, Wafaie W. Fawzi, Karim P. Manji, Christopher R. Sudfeld

Faculty Publications

Background Infants born to pregnant women living with HIV (WLHIV) are at greater risk for morbidity and mortality and may also have poorer developmental outcomes as compared with infants who are not exposed to HIV. Nutrition interventions in pregnancy may affect developmental outcomes.

Objectives This study evaluated the effect of maternal vitamin D supplementation on infant development outcomes.

Design We conducted a secondary analysis of a randomised, triple-blind, placebo-controlled trial of maternal vitamin D supplementation from June 2015 to October 2019.

Setting Antenatal care clinics in Dar es Salaam, Tanzania.

Participants Pregnant WLHIV and their offspring.

Interventions Daily 3000 IU …

Spartan Daily, September 17, 2025, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2025

Volume 165, Issue 11

Inside Wamh, January 2008, Advocate Health - Midwest

Historical Documents - Combined

West Allis Memorial Hospital, West Allis, WI: Inside WAMH is a monthly newsletter for employees, volunteers, and guests of the hospital. This issue has a feature on Acute Care for the Elderly (ACE).

Inside Wamh, February 2008, Advocate Health - Midwest

Historical Documents - Combined

West Allis Memorial Hospital, West Allis, WI: Inside WAMH is a monthly newsletter for employees, volunteers, and guests of the hospital. This issue has information on a pilot Open Medical Record program.

Inside Wamh, March 2008, Advocate Health - Midwest

Historical Documents - Combined

West Allis Memorial Hospital, West Allis, WI: Inside WAMH is a monthly newsletter for employees, volunteers, and guests of the hospital. This issue announces the hospital now has Wi-Fi.