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Articles 185461 - 185490 of 193188
Full-Text Articles in Entire DC Network
A Bibliometric Study On Research Trends And Hotspots Of Recurrent Aphthous Stomatitis, Zhifeng Song, Xuan Xiao, Zhaocheng Shi, Shangfeng Liu
A Bibliometric Study On Research Trends And Hotspots Of Recurrent Aphthous Stomatitis, Zhifeng Song, Xuan Xiao, Zhaocheng Shi, Shangfeng Liu
Journal of Dental Sciences
Abstract Background/purpose Recurrent aphthous stomatitis (RAS) is a common oral mucosal disease. Despite a variety of scientific articles have been available till date, merely a few scientometric analyses have been systematically carried out in this field. The objective of this study was to recognize the hotspots and research trends related to RAS via bibliometric approach. Materials and methods The Elsevier's Scopus database was searched to retrieve qualified literature through an advanced search strategy on 9 Feb 2023. The basic information was collected as following: article type, publication year, journals, impact factor, the count of citations, citation density, keywords, authors, contributing …
Profiles Of Peripheral B Cell Subsets In A Cohort Of Primary Sjögren's Syndrome Patients And Their Potential Clinical Significance, Yixiao Xing, Boya Li, Pan Wei, Hong Hua
Profiles Of Peripheral B Cell Subsets In A Cohort Of Primary Sjögren's Syndrome Patients And Their Potential Clinical Significance, Yixiao Xing, Boya Li, Pan Wei, Hong Hua
Journal of Dental Sciences
Abstract Background/purpose Primary Sjögren's syndrome is a prototypical autoimmune disease, with B cell dysfunction as a dominant feature. Further insights into distribution of B cell subsets in primary Sjögren's syndrome are urgently required to identify the most appropriate target subpopulation. We aimed to evaluate the profiles of B lymphocyte subpopulations in primary Sjögren's syndrome patients and to investigate their clinical significance. Materials and methods Thirty primary Sjögren's syndrome patients and 15 age-and sex-matched healthy controls were recruited. Peripheral B cell subsets were analyzed by flow cytometry. Results Compared to healthy controls, circulating CD19+ B cells, CD19+CD20− B cells, CD19+CD27−IgD+ naïve …
Maxillary Posterior Implant As A Surveyed Crown For Implant-Assisted Removable Partial Denture: A Case Report With 10-Year Follow-Up, Shing-Zeng Dung, Jea-Shen Tsai, Shyh-Yuan Lee
Maxillary Posterior Implant As A Surveyed Crown For Implant-Assisted Removable Partial Denture: A Case Report With 10-Year Follow-Up, Shing-Zeng Dung, Jea-Shen Tsai, Shyh-Yuan Lee
Journal of Dental Sciences
No abstract provided.
Cryogun Cryotherapy For The Management Of A Large Benign Oral Vascular Anomaly - A Case Report, Shih-Wen Chu, Meng-Ling Chiang, Jyh-Kwei Chen
Cryogun Cryotherapy For The Management Of A Large Benign Oral Vascular Anomaly - A Case Report, Shih-Wen Chu, Meng-Ling Chiang, Jyh-Kwei Chen
Journal of Dental Sciences
No abstract provided.
Flexible Deployment Of Dental Radiation Equipment In Large Dental Institutions: Taking The Department Of Dentistry Of National Taiwan University Hospital As An Example, Feng-Chou Cheng, Ling-Hsia Wang, Mu-Hsiung Chen, Chun-Pin Chiang
Flexible Deployment Of Dental Radiation Equipment In Large Dental Institutions: Taking The Department Of Dentistry Of National Taiwan University Hospital As An Example, Feng-Chou Cheng, Ling-Hsia Wang, Mu-Hsiung Chen, Chun-Pin Chiang
Journal of Dental Sciences
No abstract provided.
Palatine Tonsilloliths Incidentally Found On The Panoramic Radiograph, Feng-Chou Cheng, Ching-En Meng, Julia Yu-Fong Chang, Chun-Pin Chiang
Palatine Tonsilloliths Incidentally Found On The Panoramic Radiograph, Feng-Chou Cheng, Ching-En Meng, Julia Yu-Fong Chang, Chun-Pin Chiang
Journal of Dental Sciences
No abstract provided.
Medication-Related Osteonecrosis Of The Jaw In A Patient With Rheumatoid Arthritis With Suspected Involvement Of Methotrexate And Tocilizumab, Keisuke Seki, Atsushi Kobayashi, Norihito Takahashi, Atsushi Kamimoto
Medication-Related Osteonecrosis Of The Jaw In A Patient With Rheumatoid Arthritis With Suspected Involvement Of Methotrexate And Tocilizumab, Keisuke Seki, Atsushi Kobayashi, Norihito Takahashi, Atsushi Kamimoto
Journal of Dental Sciences
No abstract provided.
A Survey Of The Participants’ Learning Outcomes After Finishing The Dental Radiology Course For The Continuing Education Of Medical Radiation Technologists In Taiwan, Chung-Pin Chiang, Feng-Chou Cheng, Mu-Hsiung Chen, Yu-Wen Wang, Chun-Hung Chen, Kun-Lung Pin, Chien-Yi Ting
A Survey Of The Participants’ Learning Outcomes After Finishing The Dental Radiology Course For The Continuing Education Of Medical Radiation Technologists In Taiwan, Chung-Pin Chiang, Feng-Chou Cheng, Mu-Hsiung Chen, Yu-Wen Wang, Chun-Hung Chen, Kun-Lung Pin, Chien-Yi Ting
Journal of Dental Sciences
Abstract Background/purpose In Taiwan, there are very few dental radiology curricula in medical radiation education system. This study assessed the participants’ learning outcomes after finishing the dental radiology course for the continuing education of medical radiation technologists in Taiwan. Materials and methods This study used the questionnaire survey to evaluate the participants’ learning outcomes after finishing the dental radiology course for the continuing education of medical radiation technologists in Taiwan. Results In this study, 85 participants filled out the questionnaires completely after finishing the dental radiology course. The majority of participants agreed that dental radiology courses were rare in the …
Adverse Effects Of Electronic Cigarettes On Human Health, Chung-Pin Chiang, Yu-Hsueh Wu
Adverse Effects Of Electronic Cigarettes On Human Health, Chung-Pin Chiang, Yu-Hsueh Wu
Journal of Dental Sciences
Abstract Many people have associated e-cigarettes with adjectives such as trendy and cool, and regarded vaping as “a safer alternative to cigarette smoking”. Compared with the conventional cigarettes, the public is less familiar with the dangers of e-cigarettes. E-cigarettes produce an aerosol by heating the e-liquid (usually comprising nicotine, flavorings, propylene glycol, vegetable glycerin, and other additives). Harmful substances are generated during the vaporization, such as formaldehyde. Cellular damages and DNA hypermethylation are also found to be associated with vaping. We reviewed the clinical neoplastic cases of patients with vaping history (three oral squamous cell carcinomas, one conjunctival squamous intraepithelial …
Intramucosal Nevus On The Posterior Hard Palate, Andy Sun, Ming-Jay Hwang, Ying-Tai Jin, Chun-Pin Chiang
Intramucosal Nevus On The Posterior Hard Palate, Andy Sun, Ming-Jay Hwang, Ying-Tai Jin, Chun-Pin Chiang
Journal of Dental Sciences
No abstract provided.
The First Dental Clinic On A Navy Warship Of Taiwan, Chung-Pin Chiang, Feng-Chou Cheng, Ling-Hsia Wang
The First Dental Clinic On A Navy Warship Of Taiwan, Chung-Pin Chiang, Feng-Chou Cheng, Ling-Hsia Wang
Journal of Dental Sciences
No abstract provided.
Efficacy Of Antimicrobial Peptide P113 Oral Health Care Products On The Reduction Of Oral Bacteria Number And Dental Plaque Formation In A Randomized Clinical Assessment, Wei-Jen Chang, Yi-Fan Wu, Bor-Cheng Han, Wen-Yi Lin, Sin-Yu Wang, Thu Ya Linn, Hsueh-Wen Hsu, Chih-Chieh Wen, Hung-Yi Liu, Yi-Hua Chen
Efficacy Of Antimicrobial Peptide P113 Oral Health Care Products On The Reduction Of Oral Bacteria Number And Dental Plaque Formation In A Randomized Clinical Assessment, Wei-Jen Chang, Yi-Fan Wu, Bor-Cheng Han, Wen-Yi Lin, Sin-Yu Wang, Thu Ya Linn, Hsueh-Wen Hsu, Chih-Chieh Wen, Hung-Yi Liu, Yi-Hua Chen
Journal of Dental Sciences
Abstract Background/purpose Dental plaque is the main cause leading to the dental caries and periodontal diseases. The main purpose of this study was to test the efficacy of oral spray containing the antimicrobial peptide P-113 on the reduction of oral bacteria number and dental plaque formation in a randomized clinical assessment. Materials and methods This study was divided into two parts. In Part A, we investigated the user experiences with the P-113 containing oral spray. In part B, 14 subjects in the experimental group used the P-113-containing oral spray, while 14 subjects in the control group used a placebo without …
The High Risk Of The Development Of Medication-Related Osteonecrosis Of The Jaw In Prostate Cancer Patients With Bone Metastasis: A Case Report, Feng-Chou Cheng, Mu-Hsiung Chen, Chun-Pin Chiang
The High Risk Of The Development Of Medication-Related Osteonecrosis Of The Jaw In Prostate Cancer Patients With Bone Metastasis: A Case Report, Feng-Chou Cheng, Mu-Hsiung Chen, Chun-Pin Chiang
Journal of Dental Sciences
No abstract provided.
Patient Considerations For Orthodontists: A Comparative Study Of University Students In Malaysia And Taiwan, Hsin-Chung Cheng, Tee Chi Yuo, Daniel Chen, Renu Sarah Samson, Eby Varghese, Od Bayarsaikhan
Patient Considerations For Orthodontists: A Comparative Study Of University Students In Malaysia And Taiwan, Hsin-Chung Cheng, Tee Chi Yuo, Daniel Chen, Renu Sarah Samson, Eby Varghese, Od Bayarsaikhan
Journal of Dental Sciences
Abstract Background/purpose Patients' considerations when choosing an orthodontist are influenced by many factors, including background, ethnicity, and location. Accordingly, this study aimed to identify factors influencing patients’ considerations when selecting an orthodontist in both Malaysia and Taiwan. Materials and methods In total, 248 dental students from Taipei Medical University and 110 dental students from Manipal University College Malaysia were selected for this study. Participants' considerations when selecting an orthodontist were assessed using a questionnaire survey. The questionnaire collected data regarding participants’ demographic characteristics and their preferences regarding clinical settings, orthodontist attributes, administrative systems, and the influence of social media. The …
Dental Implants Could Be Considered As A Reliable Treatment In Florid Cemento-Osseous Dysplasia Patients After Total Excision, Wei-Che Tsai, Yang-Che Wu, Yoichi Ohiro, Chih-Yuan Fang
Dental Implants Could Be Considered As A Reliable Treatment In Florid Cemento-Osseous Dysplasia Patients After Total Excision, Wei-Che Tsai, Yang-Che Wu, Yoichi Ohiro, Chih-Yuan Fang
Journal of Dental Sciences
No abstract provided.
Giant Cell Fibroma On The Dorsal Tongue, Andy Sun, Yi-Pang Lee, Ying-Tai Jin, Chun-Pin Chiang
Giant Cell Fibroma On The Dorsal Tongue, Andy Sun, Yi-Pang Lee, Ying-Tai Jin, Chun-Pin Chiang
Journal of Dental Sciences
No abstract provided.
Fully Digital Workflow From Bone Augmentation To Implant-Supported Prosthetic Reconstruction, Ufuk Tatli, Koray Soygun, Orcan Yuksel
Fully Digital Workflow From Bone Augmentation To Implant-Supported Prosthetic Reconstruction, Ufuk Tatli, Koray Soygun, Orcan Yuksel
Journal of Dental Sciences
No abstract provided.
Effects Of Handheld Nonthermal Plasma On The Biological Responses, Mineralization, And Inflammatory Reactions Of Polyaryletherketone Implant Materials, Tzu-Yu Peng, Chien-Fu Tseng, I-Ta Lee, Sheng-Han Wu, Hsin-Ming Chen, Yuichi Mine, Sang-Heng Kok
Effects Of Handheld Nonthermal Plasma On The Biological Responses, Mineralization, And Inflammatory Reactions Of Polyaryletherketone Implant Materials, Tzu-Yu Peng, Chien-Fu Tseng, I-Ta Lee, Sheng-Han Wu, Hsin-Ming Chen, Yuichi Mine, Sang-Heng Kok
Journal of Dental Sciences
Abstract Background/purpose The handheld nonthermal plasma (HNP) treatment may alter the surface properties, bone metabolism, and inflammatory reactions of polyaryletherketone (PAEK) dental implant materials. This study tested whether the HNP treatment might increase the biocompatibility, surface hydrophilicity, surface free energies (SFEs), and the cell adhesion and mineralization capability of PAEK materials. Materials and methods Disk-shaped samples of titanium (Ti), zirconia (Zr), polyetheretherketone (PEEK [PE]), and polyetherketoneketone (PEKK [PK]) were subjected to HNP treatment and termed as TiPL, ZrPL, PEPL, and PKPL, respectively. Water-surface reactions were examined using a goniometer. MG-63 cells were cultured on all samples to assess the cell …
Factors Derived From Human Exfoliated Deciduous Teeth Stem Cells Reverse Neurological Deficits In A Zebrafish Model Of Parkinson's Disease, Chung-Hsing Li, Yong-Ren Chen, Chin-Chean Wong, Yi-No Chen, Bing-Heng Yang, Po-Hui Lee, Chia-Yang Shiau, Kuo-Chuan Wang
Factors Derived From Human Exfoliated Deciduous Teeth Stem Cells Reverse Neurological Deficits In A Zebrafish Model Of Parkinson's Disease, Chung-Hsing Li, Yong-Ren Chen, Chin-Chean Wong, Yi-No Chen, Bing-Heng Yang, Po-Hui Lee, Chia-Yang Shiau, Kuo-Chuan Wang
Journal of Dental Sciences
Abstract Background/purpose Mesenchymal stem cells exhibit therapeutic efficacy for brain injury. This study examined the effect of mesenchymal stem cells derived from human exfoliated deciduous teeth (SHED) on alleviating symptoms of Parkinson's disease (PD). Materials and methods SHED were isolated to examine the biosafety and bioavailability of stem cells derived from human exfoliated deciduous teeth-derived conditioned medium (SHED-CM) for the alleviation of PD symptoms in a 6-hydroxydopamine (6-OHDA)-induced PD zebrafish model. Results SHED-CM administration did not induce neurological, skin or muscle toxicity in control zebrafish at any dose, and estrogen equivalent testing showed no chronic toxicants. Induction of PD with …
The Significance Of Using Dental Elements As A Design Theme: A Case Report Of Modular Mobile Dental System In The 2023 Young Designers’ Exhibition In Taiwan, Chun-Pin Chiang, Feng-Chou Cheng, Ling-Hsia Wang
The Significance Of Using Dental Elements As A Design Theme: A Case Report Of Modular Mobile Dental System In The 2023 Young Designers’ Exhibition In Taiwan, Chun-Pin Chiang, Feng-Chou Cheng, Ling-Hsia Wang
Journal of Dental Sciences
No abstract provided.
Incremental Net Benefit Of Extending Human Papillomavirus Vaccine To Boys In Oropharyngeal Cancer Burden: Meta-Analysis Of Cost-Effectiveness Studies, Adikara Pagan Pratama, Su-Feng Chen, Shih-Chieh Liao, Wei-Chia Su, Jian-Hong Yu
Incremental Net Benefit Of Extending Human Papillomavirus Vaccine To Boys In Oropharyngeal Cancer Burden: Meta-Analysis Of Cost-Effectiveness Studies, Adikara Pagan Pratama, Su-Feng Chen, Shih-Chieh Liao, Wei-Chia Su, Jian-Hong Yu
Journal of Dental Sciences
Abstract Background/purpose The incidence of human papillomavirus (HPV)-related oropharyngeal cancer (OPC) is increasing worldwide. HPV vaccines have shown efficacy in preventing diseases in both males and females. Therefore, there is a need to develop cost-effective strategies for HPV vaccines to prevent HPV-related OPC. This meta-analysis aimed to evaluate cost-effectiveness using the global mean of incremental cost-effectiveness ratios compared to the willingness-to-pay threshold and incremental net benefits (INBs) of HPV vaccination strategies between boys’ extension vaccine and girls only. These recommendations will be useful for countries that have not implemented universal HPV vaccines in national programs, such as Taiwan. Materials and …
Influence Of Handheld Nonthermal Plasma On Shear Bond Strength Of Polyaryletherketone To Resin-Matrix Cement, Tzu-Yu Peng, Huei-Yu Huang, Szu-Yu Lai, Fu-Ting Lee, Yang-Che Wu, Sheng-Wei Feng, Hiroki Nikawa
Influence Of Handheld Nonthermal Plasma On Shear Bond Strength Of Polyaryletherketone To Resin-Matrix Cement, Tzu-Yu Peng, Huei-Yu Huang, Szu-Yu Lai, Fu-Ting Lee, Yang-Che Wu, Sheng-Wei Feng, Hiroki Nikawa
Journal of Dental Sciences
Abstract Background/purpose Challenges exist regarding the bonding efficiency of polyaryletherketone (PAEK), a high-performance thermoplastic, attributed to its chemical inertness and hydrophobic surface, hindering effective bonding with resin-matrix cement. This research explored the impact of handheld nonthermal plasma (HNP), under varying operational parameters, on PAEK surface wettability and changes in bonding performance with cement. Materials and methods Three types of disc-shaped PEAK specimens were prepared, with surface treatments categorized as grinding, airborne-particle abrasion (APB), and HNP. Surface wettability was analyzed using a contact angle analyzer (n = 10). Specimens were bonded with resin cement and subjected to artificial aging tests: distilled …
Prevention Of Medication-Related Osteonecrosis Of The Jaw In Mice By Adipose-Derived Stem Cells Associated With Activated Autophagic Flux, Xian Dong, Shuo Chen, Yang He, Yi Zhang
Prevention Of Medication-Related Osteonecrosis Of The Jaw In Mice By Adipose-Derived Stem Cells Associated With Activated Autophagic Flux, Xian Dong, Shuo Chen, Yang He, Yi Zhang
Journal of Dental Sciences
Abstract Background/purpose Medication-related osteonecrosis of the jaw (MRONJ) represents a rare yet serious adverse reaction associated with the prolonged use of anti-bone resorptive or anti-angiogenic agents. This study aimed to investigate the impact and underlying mechanisms of adipose-derived stem cells (ADSCs) in preventing MRONJ in a mouse model. Materials and methods Following tooth extraction in MRONJ mice, ADSCs or PBS were administered via the tail vein. The healing progress of gingival epithelium and the extraction socket was assessed using a stereoscopic microscope and histological analysis. Immunofluorescence was employed to examine markers associated with autophagy (LC3 and SQSTM1) and apoptosis (Cleaved-CASP …
Underlying Bone Change In Oral Squamous Cell Carcinoma Observed From Magnetic Resonance Imaging And Computed Tomography: Potential Implications For Tumor Aggressiveness And Prognosis, Kyung-Hoe Huh, Gyu-Dong Jo, Kyu-Young Oh, Jo-Eun Kim, Won-Jin Yi, Min-Suk Heo, Sam-Sun Lee
Underlying Bone Change In Oral Squamous Cell Carcinoma Observed From Magnetic Resonance Imaging And Computed Tomography: Potential Implications For Tumor Aggressiveness And Prognosis, Kyung-Hoe Huh, Gyu-Dong Jo, Kyu-Young Oh, Jo-Eun Kim, Won-Jin Yi, Min-Suk Heo, Sam-Sun Lee
Journal of Dental Sciences
Abstract Background /purpose In cases where oral squamous cell carcinoma (OSCC) invades the jawbone, clinicians frequently observe abnormal attenuation on computed tomography (CT) and pathologic signal intensity (SI) on magnetic resonance (MR) imaging of the affected underlying bone marrow. This study introduced a concept of “underlying bone change” to examine its association with clinicopathological features and prognosis of OSCC, as well as its correlation with medullary invasion. Materials and methods We enrolled 93 consecutive patients diagnosed with OSCC, who underwent mandibulectomy between 2010 and 2016. CT and MR images, along with electronic medical records, were reviewed to evaluate correlations between …
Effects Of Lactobacillus Pentosus Postbiotics On Fibrotic Response In Arecoline-Induced Oral Fibrogenesis, Po-Yu Yang, Chin-Chu Chen, You-Shan Tsai, Yi-Wen Liao, Min Yee Ng, Chun-Chung Huang, Cheng-Chia Yu, San-Fu Hong
Effects Of Lactobacillus Pentosus Postbiotics On Fibrotic Response In Arecoline-Induced Oral Fibrogenesis, Po-Yu Yang, Chin-Chu Chen, You-Shan Tsai, Yi-Wen Liao, Min Yee Ng, Chun-Chung Huang, Cheng-Chia Yu, San-Fu Hong
Journal of Dental Sciences
Abstract Background/purpose Oral submucous fibrosis (OSF), characterized by excessive collagen deposition by myofibroblasts, is often linked to Areca nuts consumption. Probiotics consumption has shown protective effects against fibrotic diseases, and recently, their metabolic byproducts, known as postbiotics, have demonstrated superior advantages over probiotics. However, studies on the therapeutic impact of postbiotics on OSF have been scarce. Therefore, this study aims to examine the effect of PostBio GK4, a postbiotic derived from Lactobacillus pentosus GK4 , on OSF and explore its underlying mechanisms. Materials and methods The cytotoxicity of GK4 in normal buccal mucosal fibroblasts (BMFs) and fibrotic BMFs (fBMFs) were …
Enhanced Bone Formation Of Rat Mandibular Bone Defects With Collagen Membranes Loaded On Bone Morphogenetic Protein-9, Hiroki Kondo, Tadahiro Takayama, Takashi Onizawa, Shunsuke Isobe, Natsuko Tanabe, Naoto Suzuki, Seiichi Yamano, Shuichi Sato
Enhanced Bone Formation Of Rat Mandibular Bone Defects With Collagen Membranes Loaded On Bone Morphogenetic Protein-9, Hiroki Kondo, Tadahiro Takayama, Takashi Onizawa, Shunsuke Isobe, Natsuko Tanabe, Naoto Suzuki, Seiichi Yamano, Shuichi Sato
Journal of Dental Sciences
Abstract Background/purpose Bone morphogenetic protein-9 (BMP-9) has demonstrated multiple advantages in promoting osteogenesis. Our previous findings have indicated that the use of an absorbable collagen membrane (ACM) as a carrier for growth factors is effective in stimulating bone regeneration. The objective of this study was to assess the synergistic impact of BMP-9 incorporated into ACM (ACM/BMP-9) on bone formation within rat mandibular bone defects. Materials and methods Circular bone defects of critical size were surgically induced on both sides of the rat mandibular bone, with subsequent random allocation into distinct groups: control, ACM alone, and ACM loaded with low (0.5 …
Cementocyte-Derived Extracellular Vesicles Regulate Osteoclastogenesis And Osteoblastogenesis, Eiji Nemoto, Jiajun Li, Yukihiko Sakisaka, Kentaro Maruyama, Shigeki Suzuki, Kaixin Xiong, Hiroyuki Tada, Taichi Tenkumo, Satoru Yamada
Cementocyte-Derived Extracellular Vesicles Regulate Osteoclastogenesis And Osteoblastogenesis, Eiji Nemoto, Jiajun Li, Yukihiko Sakisaka, Kentaro Maruyama, Shigeki Suzuki, Kaixin Xiong, Hiroyuki Tada, Taichi Tenkumo, Satoru Yamada
Journal of Dental Sciences
Abstract Background/purpose Cementum shares many properties with bone; however, in contrast to bone, it is not innervated or vascularized and has a limited capacity for remodeling. Osteocytes located in the lacunae-canalicular system of bone tissue play a central role in bone remodeling by communicating with osteoblasts and osteoclasts. Although cementocytes are present in cellular cementum and are morphologically similar to osteocytes, it remains unclear whether they are involved in the dynamic functional regulation of metabolism in cementum. The present study focused on the extracellular vesicles (EVs) secreted by cementocytes and examined their effects on osteoclasts and osteoblasts. Materials and methods …
Orthodontic Tension Promotes Cementoblast Mineralization By Regulating Autophagy, Weiran Li, Yi Zhao, Yuhui Yang, Hao Liu, Jiayi Wang, Yiping Huang
Orthodontic Tension Promotes Cementoblast Mineralization By Regulating Autophagy, Weiran Li, Yi Zhao, Yuhui Yang, Hao Liu, Jiayi Wang, Yiping Huang
Journal of Dental Sciences
Abstract Background/purpose External root resorption is a main side effect of orthodontic treatment and is more likely to occur on the pression side than the tension side. To explore the potential protective mechanisms on the tension side, this study investigated the influence of mechanical tension on cementoblast mineralization and elucidated the role of autophagy in mediating this process. Materials and methods Mechanical tension was applied to cementoblasts using iStrain. The expression of mineralization-related and autophagy-related markers was detected by qRT-PCR, Western blot analysis, and immunofluorescence staining. RNA sequencing identified key regulators. Immunohistochemical staining assessed related markers expression in in vivo …
Evaluating The Efficacy Of Leading Large Language Models In The Japanese National Dental Hygienist Examination: A Comparative Analysis Of Chatgpt, Bard, And Bing Chat, Masaki Morishita, Shino Yamaguchi, Hikaru Fukuda, Kosuke Muraoka, Taiji Nakamura, Izumi Yoshioka, Inho Soh, Kentaro Ono, Shuji Awano
Evaluating The Efficacy Of Leading Large Language Models In The Japanese National Dental Hygienist Examination: A Comparative Analysis Of Chatgpt, Bard, And Bing Chat, Masaki Morishita, Shino Yamaguchi, Hikaru Fukuda, Kosuke Muraoka, Taiji Nakamura, Izumi Yoshioka, Inho Soh, Kentaro Ono, Shuji Awano
Journal of Dental Sciences
Abstract Background/purpose Large language models (LLMs) such as OpenAI's ChatGPT, Google's Bard, and Microsoft's Bing Chat have shown potential as educational tools in the medical and dental fields. This study evaluated their effectiveness using questions from the Japanese national dental hygienist examination, focusing on textual information only. Materials and methods We analyzed 73 questions from the 32nd Japanese national dental hygienist examination, conducted in March 2023, using LLMs ChatGPT-3.5, GPT-4, Bard, and Bing Chat. Each question was categorized into one of nine domains. Standardized prompts were used for all LLMs, and Fisher's exact test was applied for statistical analysis. Results …
Potential Different Immune Phenotypes Of Macrophages In Oral Lichen Planus By Integrating Immunofluorescence Double Staining And Single-Cell Rna Sequencing, Kai Sun, Qianqian Zhang, Ran Zhao, Xuemin Shen
Potential Different Immune Phenotypes Of Macrophages In Oral Lichen Planus By Integrating Immunofluorescence Double Staining And Single-Cell Rna Sequencing, Kai Sun, Qianqian Zhang, Ran Zhao, Xuemin Shen
Journal of Dental Sciences
Abstract Background/purpose Oral lichen planus (OLP) is a chronic inflammatory disease with obscure etiopathogenesis. Macrophages play an important role in interaction between innate and adaptive immunity. This study aimed to investigate the macrophage phenotypes and obtain more comprehensive gene characteristics of macrophages in OLP. Materials and methods Double cluster of differentiation (CD) 68/CD86 and CD68/CD206 immunofluorescence staining was conducted in 11 biopsy-proven OLP tissue samples and 5 health control (HC) to represent M1 and M2 macrophages, respectively. The number of positively stained cells was manually counted, and the density was calculated. Furtherly, OLP single-cell dataset GSE211630 was downloaded from Gene …