Digital Commons Network^™

Relationship Between Abo Blood Type And Clinical–Pathological Characteristics With Prostate Cancer Patients In Khartoum State, Khartoum, Sudan, Wafa Mobarak Ahmed Ali, Asim Alaaedin Osman, Gad Allah Modawe

Iraqi National Journal of Medicine

Background: Recent studies have demonstrated the association between ABO blood group and prostate cancer (PC), as well as the various factors associated with PC, including age, family history, ethnicity, and certain viruses. Aim: To demonstrate the association between ABO blood groups and PC and to correlate it with the demographic and clinical features of our studied population. Methods: A descriptive cross-sectional hospital-based study was conducted at the Radiation and Isotopes Center—Khartoum (RICK) in Khartoum state from April 2018 to April 2019. From a study population of 389 PC patients (RICK), a total of 101 were selected. Data was analyzed using …

Synthetic Oct-A Blood Vessel Maps Using Fundus Images And Generative Adversarial Networks, Ashanul Haque, Mohd Wajid Ali Khan, Khalaf M Alenezi, Raoudha Soury, Muhammad S Khan, Shahzaib Ahamad, Md Mushtaque, Dinesh Gupta

Faculty, Staff and Student Publications

The design and development of new small-molecule glycation inhibitors are essential for preventing various chronic diseases, including diabetes mellitus, immunoinflammation, cardiovascular, and neurodegenerative diseases. 4-Thiazolidinone or thiazolidine-4-one is a well-known heterocyclic compound with the potential to inhibit the formation of advanced glycation end products. In the present work, we report the synthesis and characterization of four new 5-arylidene 3-cyclopropyl-2-(phenylimino)thiazolidin-4-one (1–4) compounds and their human serum albumin glycation inhibitory activity. One of the compounds 5-(2H-1,3-benzodioxol-5-ylmethylidene)-3-cyclopropyl-2-(phenylimino)-1,3-thiazolidin-4-one (3) showed potent inhibition in the synthesis of initial, intermediary, and final products of glycation reactions. Besides, conformational …

A Road Map For The Treatment Of Pediatric Diffuse Midline Glioma, Carl Koschmann, Wajd N Al-Holou, Marta M Alonso, Jamie Anastas, Pratiti Bandopadhayay, Tara Barron, Oren Becher, Rodrigo Cartaxo, Maria G Castro, Chan Chung, Madison Clausen, Derek Dang, Robert Doherty, Ryan Duchatel, Matthew Dun, Mariella Filbin, Andrea Franson, Stefanie Galban, Marc Garcia Moure, Hugh Garton, Pruthvi Gowda, Joana Graca Marques, Cynthia Hawkins, Allison Heath, Esther Hulleman, Sunjong Ji, Chris Jones, Lindsay Kilburn, Cassie Kline, Michael A Koldobskiy, Daniel Lim, Pedro R Lowenstein, Q Richard Lu, Joanna Lum, Stephen Mack, Suresh Magge, Bernard Marini, Donna Martin, Neena Marupudi, Dana Messinger, Rajen Mody, Meredith Morgan, Mateus Mota, Karin Muraszko, Sabine Mueller, Siva Kumar Natarajan, Javad Nazarian, Michael Niculcea, Nicholas Nuechterlein, Hideho Okada, Valerie Opipari, Manjunath P Pai, Sharmistha Pal, Erik Peterson, Timothy Phoenix, John R Prensner, Matthew Pun, G Praveen Raju, Zachary J Reitman, Adam Resnick, David Rogawski, Amanda Saratsis, Stefanie G Sbergio, Mark Souweidane, James M Stafford, Theophilos Tzaridis, Sujatha Venkataraman, Orazio Vittorio, Jack Wadden, Daniel Wahl, Robert J Wechsler-Reya, Viveka Nand Yadav, Xu Zhang, Qiang Zhang, Sriram Venneti

Faculty, Staff and Students Publications

Recent clinical trials for H3K27-altered diffuse midline gliomas (DMGs) have shown much promise. We present a consensus roadmap and identify three major barriers: (1) refinement of experimental models to include immune and brain-specific components; (2) collaboration among researchers, clinicians, and industry to integrate patient-derived data through sharing, transparency, and regulatory considerations; and (3) streamlining clinical efforts including biopsy, CNS-drug delivery, endpoint determination, and response monitoring. We highlight the importance of comprehensive collaboration to advance the understanding, diagnostics, and therapeutics for DMGs.

Experimental Environmental Profiles And Sloshing Dynamics Aboard Zero-G Aircraft, Pedro J. Llanos, Sathya Gangadharan, Kevin Crosby

Publications

This study presents the results of a parabolic flight experiment to study the sloshing dynamics of the magneto-active propellant management device experiment. This device utilizes a magnetoactive membrane and magnets located external to the tank to effectively damp the liquid free surface motion. This research work establishes a benchmark with sloshing analytical formulation and sensor calibration methods that can be used to characterize future research parabolic flights while providing important environmental profiles measured during flight, such as accelerations, pitch angle, velocity, temperature, total volatile content, carbon dioxide, relative humidity, magnetic field, and radiation. Correlation between these flight variables and the …

Identification Of Faulty Sensor Nodes In Wban Using Genetically Linked Artificial Neural Network, Haider Rasheed Abdulshaheed, Mayasa M. Abdulrahman, Israa Ibraheem Al_Barazanchi, Jamal Fadhil Tawfeq

Iraqi Journal for Computer Science and Mathematics

Wireless Body Area Networks (WBANs) have risen as a promising innovation for checking human physiological parameters in real time. Be that as it may, the unwavering quality and precision of WBANs depend on the right working of sensor hubs. The distinguishing proof of defective sensor hubs is vital for guaranteeing the quality of information collected by WBANs. In this paper, we propose a novel approach to recognizing faulty sensor hubs in WBAN employing a hereditarily linked artificial neural organize (GLANN). The GLANN is preparedto employa crossbreedfuzzy-genetic calculation to optimize its execution in distinguishing defective sensor hubs. The proposed approach is …

Central Washington University 2024-2025 University Catalog, Central Washington University

Course Catalogs

No abstract provided.

Enhancing Proprioception And Regulating Cognitive Load In Neurodiverse Populations Through Biometric Monitoring With Wearable Technologies, James Hutson, Piper Hutson

Faculty Scholarship

This paper considers the realm of wearable technologies and their prospective applications for individuals with neurodivergent conditions, specifically Autism Spectrum Disorders (ASDs). The study undertakes a multifaceted analysis that encompasses biomarker sensing technologies, AI-driven biofeedback mechanisms, and haptic devices, focusing on their implications for enhancing proprioception and social interaction among neurodivergent populations. While wearables offer a range of opportunities for societal advancement, a discernable gap remains: a scarcity of consumer-oriented applications tailored to the unique physiological and psychological needs of these individuals. Key takeaways underscore the emergent promise of tailored auditory stimuli in workplace dynamics and the efficacy of haptic …

Logos-Sophia, Elliott Norman, Donald Wayne Viney, Keith Elliott Perkins, Addyson Kay Campbell, Hunter Hinds, Scott Squires

LOGOS-SOPHIA: The Journal of the PSU Philosophical Society

Logos-Sophia, Volume 17, Spring 2024. The Journal of the Pittsburg State University Philosophical Society has largely been a student publication with occasional faculty contribution

Profound Hypothyroidism And New Onset Dilated Cardiomyopathy: A Case Report, Savannah Grunhard, Rebecca A. Taylor, Osman Perez

South Atlantic Division GME Research Day 2024

No abstract provided.

An Expository Analysis Of Textbook Usage In Classical Settings For High School Biology, Kristen Bissontz

Master of Arts in Classical Studies

AN EXPOSITORY ANALYSIS OF TEXTBOOK USAGE IN CLASSICAL SETTINGS FOR HIGH SCHOOL BIOLOGY

Kristen Bissontz

Southeastern University, Lakeland FL

The classical model of education has reemerged as a viable alternative to the modern education system. Many of the disciplines taught in a classical school, program or home education scenario appear to align with the classical philosophy with the exception of the sciences. This paper serves to uncover if textbooks are the primary source in classical settings, what resources are utilized, and offers suggestions to better align with the classical pedagogy.

A small sample of classical schools and programs in a …

Sleep, Sebastian Mark

Theses & ETDs

This thesis delves into the realm of sleep issues and disorders, probing the intricacies of optimal sleep patterns and the factors influencing them. At the core of this inquiry lies the persistent question: “If sleep is paramount, why do some people struggle to attain it?” The research goal is to identify the biological and environmental elements that impede a person’s ability to obtain sufficient rest. I collected data about myself every day from January 4th to May 5th, from diary entries and a wristband that tracks physical activity and sleep metrics throughout the day and night. Using statistical analysis and …

Enzyme Kinetic Characterization And Quantitation Of 2-Hydroxyglutarate Production By C.Elegans Isocitrate Dehydrogenase-1 Enzymes: Wild-Type Idh-1 And Mutant Enzymes G98n And R133h., Melissa Bouchard

Theses & ETDs

The metabolic enzyme isocitrate dehydrogenase (IDH-1) is the C. elegans ortholog of human cytosolic IDH1. The mechanism for both the human and the C. elegans IDH1 enzymes reversibly convert the substrate isocitrate (ICT) to α-ketoglutarate (αKG). The IDH-1 enzyme is particularly interesting due to the association of certain IDH1 mutations to human cancers. The mutations that are associated with oncogenesis are shown to inhibit the activity of IDH1 by introducing a neomorphic activity that converts αKG to α-hydroxyglutaric acid, also called 2- hydroxyglutarate (2HG).To determine if IDH-1 may be a reliable model system to explore the cellular abnormalities produced by …

Gonzaga University Factbook 2024-25, Institutional Research, Gonzaga University

Institutional Research

The Gonzaga University Factbook contains information on student enrollments, demographic profiles, admissions statistics, majors, retention and graduation rates, degree completions, faculty information, and more. It is updated annually with the most current and commonly-needed information about Gonzaga University.

Platform-Independent Estimation Of Human Physiological Time From Single Blood Samples, Yitong Huang, Rosemary Braun

Mathematics Sciences: Faculty Publications

Abundant epidemiological evidence links circadian rhythms to human health, from heart disease to neurodegeneration. Accurate determination of an individual's circadian phase is critical for precision diagnostics and personalized timing of therapeutic interventions. To date, however, we still lack an assay for physiological time that is accurate, minimally burdensome to the patient, and readily generalizable to new data. Here, we present TimeMachine, an algorithm to predict the human circadian phase using gene expression in peripheral blood mononuclear cells from a single blood draw. Once trained on data from a single study, we validated the trained predictor against four independent datasets with …

Understanding Health-Seeking Decision-Making Process And Behavior Among Haitian Immigrants: A Grounded Theory Approach, Shelleta Ladonice

Graduate Thesis and Dissertation 2023-2024

Black people in the U.S. die at younger ages, have significantly higher rates of death from treatable medical conditions, are more likely to have late-stage breast and colon cancer diagnoses and more likely to die from these cancers, and are at higher risk for chronic illnesses compared to other racial and ethnic groups. Accessing healthcare is crucial to health and well-being; however, U.S. immigrants' use of healthcare services is far less than native-born Americans. Haitian immigrants experience health disparities at the highest rate compared to other Black immigrants in the U.S. Given their unique history, culture, and immigration experience, it …

Utilizing Internet Memes In Senior High School Biology To Improve Gen Z’S Academic Achievement, Attitude, And Self-Efficacy, Alyanna Nicole Carlos, Emmanuel D. Delocado

Biology Faculty Publications

Generation Z learners’ short attention span challenges educators to design engaging teaching methods that capture their interest. This quantitative study investigates the effect of memes, which are popular internet media, on non-STEM Gen Z high school students’ academic achievement, attitude, and self-efficacy in biology. Two groups of Grade 11 participants (n=243) were taught cellular division and genetics lessons through two different approaches. The results demonstrate that the experimental group which was taught using meme-infused materials had statistically significantly higher post-test scores (21.46 ± 4.41 out of 30; independent t-test = 0.00) than students who were taught with materials with no …

Advanced Optical Biosensing Using Ratiometric Fluorescent Polymer Dots And Nanozyme, Shuyi He

Dissertations and Theses

Biosensors have been deeply valued and widely used in fermentation technology, environmental monitoring, food engineering, clinical medicine, and the military. However, current biosensors still face many technical challenges, such as miniaturization, convenience, high precision, and low power consumption which restrict the popularization and development of biosensors. Meeting these challenges require the development of advanced materials and technologies. Optical biosensors offer distinct advantages such as high sensitivity, rapid response time, and the potential for miniaturization, making them ideal for overcoming the existing limitations. My research in this dissertation explores the development and application of advanced functional nanomaterials in optical biosensing, focusing …

Fda Modernization Act 2.0: The Beginning Of The End For Animal Testing In Drug Development, Julia Williams

Animal Law Review

Historical drug testing protocols utilized animal testing to determine whether drugs were safe and effective for use in humans. However, recognizing that testing drugs on other species is potentially dangerous for humans, troubled by failures, unnecessarily expensive, and time consuming, the FDA Modernization Act 2.0, passed in December 2022, removed animal testing as a requirement for new drug applications. While this was an important step forward, a notable failure of that Act is that it did not go far enough to end animal testing. Accordingly, this Article proposes an FDA Modernization Act 3.0.

The FDA Modernization Act 3.0 would ensure …

Cyclistai: A Smartphone Solution For Cyclist Stress Assessment Using Deep Learning, Aairish Singh

Computer Science and Engineering Theses - Archive

Cycling presents a compelling solution for promoting personal health and environmental well-being, particularly for short-distance travel. Despite its numerous advantages, cycling uptake in the United States remains disproportionately low, primarily due to safety concerns. Traditional frameworks for assessing cyclist stress are hindered by their impracticality and inability to provide real-time evaluations. Self-report surveys and physiological measurements offer alternative approaches but suffer from limitations such as retrospective reporting biases and accessibility challenges, respectively. This thesis introduces CyclistAI, a novel smartphone-based cyclist stress assessment model that leverages context sensing. By combining Convolutional Neural Network (CNN) and Long Short-Term Memory (LSTM) techniques, CyclistAI …

Exploring The Impact Of Diabetes On Feet: Analysis Of Foot Ulcers With A Focus On Eczema-Related Considerations, Namlhun Jachung

Pitzer Senior Theses

Diabetes mellitus, a chronic metabolic disorder, has far-reaching consequences on various organ systems, with the lower extremities being particularly susceptible to complications. This study delves into the profound effects of diabetes on the feet, specifically examining the interplay between diabetes-induced foot ulcers, and potential complications arising from coexisting eczema. Two distinct experiments were designed to investigate critical aspects of this complex relationship.

The first experiment aims to compare Transepidermal Water Loss (TEWL) levels among diabetic patients with and without eczema. The study involves a cohort of diabetic patients, stratified based on the presence or absence of eczema, and measured TEWL …

The Origin Of Educational Technology In China, Long Li

Journal of Educational Technology Development and Exchange (JETDE)

Educational Technology is the means and methods employed in educational activities. Since the inception of education, there has been a parallel development of Educational Technology with a rich historical background. The entire evolutionary process of Educational Technology can be divided into three stages: Pre-Educational Technology, Current Educational Technology, and Post-Educational Technology, corresponding to the past, present, and future of Educational Technology. Throughout history, the Chinese nation has made irreplaceable contributions to the creation and inheritance of human civilization. The educational philosophy embedded in the discussions of education and technology among various schools of thought in ancient China and the educational …

A Cfd Framework To Study Complex Effects Relating To Airborne Viral-Pathogen Transmission, Rajendra Shrestha Mr.

Graduate Thesis and Dissertation 2023-2024

This research used computational fluid dynamics (CFD) to examine the behavior of airborne droplets released during respiratory events. The CFD model utilizes an Eulerian-Lagrangian approach, with turbulence resolved using the Spalart-Allmaras detached eddy simulation. The first part investigates airborne transmission and how modifying saliva during a sneeze impacts this process. The study employs CFD to simulate these respiratory events in a ventilated room. It finds that larger droplets alone are insufficient for droplet settling due to secondary breakdown processes. Modifiers that increase the Ohnesorge number show resistance to aerosolization from secondary breakup, resulting in more droplets with high settling rates, …

Adaptable And Trustworthy Machine Learning For Human Activity Recognition From Bioelectric Signals, Morgan S. Stuart

Theses and Dissertations

Enabling machines to learn measures of human activity from bioelectric signals has many applications in human-machine interaction and healthcare. However, labeled activity recognition datasets are costly to collect and highly varied, which challenges machine learning techniques that rely on large datasets. Furthermore, activity recognition in practice needs to account for user trust - models are motivated to enable interpretability, usability, and information privacy. The objective of this dissertation is to improve adaptability and trustworthiness of machine learning models for human activity recognition from bioelectric signals. We improve adaptability by developing pretraining techniques that initialize models for later specialization to unseen …

Lsu General Catalog 2024-2025, Louisiana State University And Agricultural And Mechanical College

LSU General Catalog

The LSU General Catalog describes all undergraduate and graduate departments and programs with degree requirements and courses offered for each one. The LSU General Catalog includes information on registration and financial aid as well as academic services offered to all students.

An Artificially Intelligent Approach To Medical Device Monitoring, Cristian A. Rodriguez

St. Thomas Law Review

The integration of artificial intelligence (Al) in medical devices, particularly the subset of Al technologies known as machine learning, has sparked a new era of precision and efficiency in healthcare. AI/ML-enabled medical devices are proving to be invaluable as they have already improved patient diagnosis, treatment, and disease prediction. As machine learning continues to be adopted in medical devices, the U.S. Food and Drug Administration (FDA) continues to receive more marketing submissions and pre-submissions for AI/ML-enabled medical devices, a trend that is expected to increase over time. While the FDA has made significant progress in proposing regulatory frameworks that will …

Analysis Of The Magnetohydrodynamic Effects On Non-Newtonian Fluid Flow In An Inclined Non-Uniform Channel Under Long-Wavelength, Low-Reynolds Number Conditions, Manjunatha Gudekote, Rajashekhar Choudhari, Prathiksha Sanil, Hanumesh Vaidya

Open Access archive

This study utilises mathematical modelling and computations to analyse the magnetohydrodynamic (MHD) effects on non-Newtonian Eyring-Powell fluid flow in an inclined non-uniform channel under long-wavelength, low Reynolds number conditions. The governing equations are solved by applying slip boundary conditions to determine the velocity, temperature, concentration, and streamline profiles. The key findings show that the magnetic parameter dampens the flow rate. The relationship between the variable viscosity, velocity, and temperature is nonlinear. The wall rigidity parameter and axial velocity are directly proportional until a threshold. Increasing inclination angles distorts streamlines. The magnetic field alters concentration contours and thermal transport. MATLAB parametric …

Efficient Design Of Neural Network Hardware Accelerator For Enhanced Performance In Deep Learning Systems, Tamador Nadem Mohaidat

Electronic Theses and Dissertations

Artificial intelligence (AI) hardware accelerator is an emerging research for several applications and domains. The hardware accelerator aims to provide high computational speed while retaining low cost and high learning performance. The main challenge is to design complex machine learning models on hardware with high performance. In this thesis, the aim is to develop the hardware implementation of perceptron within a neural network. Innovative hardware-based approaches are explored to optimize perceptron networks, enhancing accuracy, reliability, and fault tolerance while minimizing resource requirements and power consumption.

A thorough investigation into machine learning accelerators and associated challenges was initially conducted. The hardware …

Mindfulness And Mathematics: The Relationship Between A Mindful Teacher And Mathematics Intervention, Ave Mayeux

Electronic Theses and Dissertations

Adolescents in American classrooms are currently required to fulfill multiple roles, making them particularly vulnerable to stress due to intense academic demands and social pressures. This stress can be particularly challenging for adolescents who struggle with stress, anxiety, depression, and/or self-regulation. Previous research indicates a positive correlation between mindfulness practices and reduced anxiety, improved social skills and interactions, enhanced academic performance, and better self-perception. This self-study explored the implementation of mindfulness exercises in a mathematics intervention classroom by adapting and creating appropriate resources, and facilitating mindfulness exercises suitable for adolescent students. Data in this self-inquiry study was generated through meticulous …

Development Of A Novel Bioink For Human Vascularized Organoids, Bradley Allen Bromet

Masters Theses

"There is a need for a model to better mimic human physiology in the clinic, so the objective was to develop a novel bioink for a 3D tissue model to study human disease and development in a dynamic 3D environment. The results from each corresponding study helped in developing a novel bioink for use in a bio printed human vascularized organoid. The bioink composed of alginate with other natural hydrogels to function as extracellular matrix and with the addition of borophosphate bioactive glasses (BPBGs) to replace growth factors, can be used with multiple cell types to bio print the proposed …

Transforming Legal Sex, Noa Ben-Asher

North Carolina Law Review

No abstract provided.