Digital Commons Network^™

Changing Perceptions: A Philosophical Exploration Of The Phenomenon Of Light In The Urban Environment, Robin S. Miller

Full-Text Theses & Dissertations

Phenomena are extraordinary (beyond ordinary), exceptional, remarkable, or unexplainable people, events, or things which elicit words such as “wow,” “that’s incredible,” and “oh my goodness.” Within the experience of everyday life, phenomena can produce joy or despair. In the field of philosophy, phenomenon (the singular form of phenomena) is identified as an immediate object of sensation or perception and something which appears, is perceived, or observed through the senses or known cognitively. Light is often the catalyst for phenomenal moments: a flash, a rainbow, the manner with which sun strikes an object at the perfect moment to catch the viewer’s …

A Randomized Study To Examine The Ability Of A Caffeine-Based Energy Drink To Impact Energy Expenditure, Fat Oxidation, And Cognitive Performance, Joesi Krieger, Alex Schrautemeier, Anthony M. Hagele, Connor Gaige, Olivia Mennemeyer, Sydney Tolbert, Joshua Iannotti, Chad Kerksick, Chris Noonan, Petey Mumford

Faculty Scholarship

Objectives: This study evaluated the effects of acute and 28-day supplementation with a caffeine-based energy drink on energy expenditure, fat oxidation, and cognitive performance.

Methods: In a double-blind, placebo-controlled trial, 33 males and 27 females (27 ± 8 years, 26.7 ± 2.2 m/kg2) consumed a caffeinated energy drink (200 mg; CAF) or placebo (PLA) for 28 days. Indirect calorimetry assessed energy expenditure and fat oxidation at 0, 30, 60, 90, and 120 min after ingestion on day 1 and 28. Cognition assessments (Dynavision reaction, Serial Sevens, Trail Making Test A (TMT-A) and B (TMT-B)) were performed at 0, …

Visualizing The Fretboard: Arpeggiated Patterns, Muscle Memory, And Neurocognitive Strategies For The 5-String Electric Bass, Matthew Alexander Woisin

Electronic Theses and Dissertations

Proficient navigation of the 5-string electric bass requires a comprehensive mastery of various techniques and a solid understanding of music theory. This includes a detailed grasp of arpeggios, chord extensions, and the development of deeply ingrained muscle memory for precise execution. This thesis introduces a structured methodology that refines existing fretboard visualization techniques and applies a unique manner of fretboard mapping, offering a more precise framework for comprehending and unlocking the full range of the instrument. By drawing insights from music theory, music education, cognitive science, neuroscience, and technology this approach is achieved by synthesizing research on visual pattern recognition, …

Culture-Dependent Characterization Of Microbial Succession And Persistence In The Integrated Lunar/Martian Analog Habitat (Ilmah), Haley Olivia Boles

Theses and Dissertations

This study examines culture-dependent microbial monitoring in a closed lunar/Martian analog habitat, focusing on viable community dynamics relevant to long-duration missions. A standardized sampling and cultivation pipeline was implemented in ILMAH to track microbial succession and persistence under realistic operational conditions. Surface samples were collected across eight habitat zones at five mission timepoints (Days 0, 5, 10, 15, 20) during a 21-day crewed mission. Samples were concentrated post-collection and plated on chromogenic film media to quantify total aerobic bacteria (AC-R), fungi (YM-R), E. coli (EC), and S. aureus (SA). Plates were imaged and enumerated digitally; representative colonies were isolated and …

(R2135) System Dynamical Analysis For Ann-Based Numerical Solutions Of A Compartmental Model: A Bio-Mathematical Model Of Drug Diffusion Through The Compartments Of Blood And Tissue, Rakesh Kumar, Sudarshan Dhua

Applications and Applied Mathematics: An International Journal (AAM)

This paper provides a considerably efficient numerical approach to acquire the solutions of a biomathematical model administrating oral and intravenous distribution of pharmaceuticals in the human body. The proposed numerical approach based on an artificial neural network is employed to extract numerical solutions for a detailed set of ordinary differential equations and analyze the change in concentration of drug diffusion via the compartments of blood and tissue medium. We primarily focus on analyzing three different models established on the diffusion process, exercising laws of mass action and Fick’s principle. In this work, the existing model is reformulated as an optimization …

Ode To The Infomercial, Edward Wade

Open Access Theses & Dissertations

'Ode to the Infomercial' is a poetry collection in five sections which explores themes of contemporary American life, parenthood, and the media landscape. While primarily written in a narrative voice, the poetic approach is as diverse as the content. Interwoven throughout the collection is religious imagery and political posturing accompanied by healthy doses of self-criticism and humor.

Guide For Selecting Experimental Models To Study Dietary Fat Absorption, Andromeda M. Nauli, Ann Phan, Karen Mai, Kathleen Tran, Surya M. Nauli

Pharmacy Faculty Articles and Research

Dietary fat absorption is a complex, multi-step process involving digestion, enterocyte uptake, intracellular trafficking, re-esterification, and transport via lipoproteins into circulation. Because dietary fat absorption plays a central role in lipid homeostasis, metabolic syndrome, and fat malabsorption disorders, its study has a broad biomedical significance. However, experimental investigation of this process is technically challenging due to the short lifespan of enterocytes, the dual lymphatic and portal transport routes, and the need to trace the metabolic fate of absorbed lipids. This review summarizes and critically evaluates the major experimental systems used to study dietary fat absorption, highlighting their respective strengths, limitations, …

High Phosphorus Intake: The Role Of Phosphorus And Health Outcomes Through The Lens Of High Phosphorus Additive Intake, Taigen M. Mayes

Senior Honors Theses

Phosphorus is a commonly consumed mineral in the traditional human diet and plays an essential role in human physiological functions. With the use of phosphate additives, high phosphate intake has become increasingly prevalent in recent years. Phosphate is regulated in the body by a homeostasis mechanism. A disruption to the homeostasis has a link to various pathologies such as bone health, cardiovascular disease, cancers, and kidney issues. Various studies have investigated the role of phosphate and its effects on human function. Bone health, cardiovascular disease, cancer, premature aging, dementia, and kidney disease are linked with high phosphorus intake.

Cover And Front Matter

Research and Reflection on Learning and Teaching in Higher Education

Cover and Table of Contents for Volume 3 (2025)

Heat And Kidney Health: Exploring The Impact Of Rising Temperatures On Kidney Health And Vulnerable Populations, Hoimonty Mazumder

Electronic Theses and Dissertations Archive

This dissertation examines how ambient temperature influences renal health across three complementary chapters by exploring: sex-stratified temperature-urine biomarkers relationships, a global comprehensive synthesis of evidence on renal colic, and mediation effect of BP in the biological pathway between ambient temperature and proteinuria. We used repeated measurements of urinary electrolytes, 24-h urine total protein (UTP), and volume as outcomes from a stepped-wedge RCT conducted in southwest coastal Bangladesh and collected daily ambient temperature data from Bangladesh Meteorological Board (BMD). We employed piece-wise linear mixed effect models using random intercepts to demonstrate ambient temperature and urine biomarker’s relationships. We summarized global evidence …

Hydration Strategies In Ultra-Endurance Running: A Narrative Review Of Programmed Versus Thirst-Driven Approaches, Shawn C. Wierick, Rosie I. Perez, Xiujing Zhao, Brendon P. Mcdermott

Health, Human Performance and Recreation Faculty Publications and Presentations

Background/Objectives: Ultra-endurance running (UER) presents unique hydration challenges due to prolonged duration, variable terrain, environmental extremes, and gastrointestinal limitations. Athletes often use either programmed fluid intake (PFI), which prescribes fluid volumes based on estimated sweat rate, or thirst-driven fluid intake (TDFI), which relies on internal cues. This review examines the effectiveness and limitations of each strategy in the context of UER performance and safety. Methods: A narrative review was conducted using a targeted selection of peer-reviewed studies. Both laboratory- and field-based research were included to evaluate the physiological rationale, practical feasibility, and outcomes associated with PFI and TDFI. A total …

Developing A High-Throughput Machine Learning Screening Platform For Genetic And Pharmacological Modulators On Caenorhabditis Elegans Seizure Behavior, Paul A. Scarpinato

Electronic Theses and Dissertations 2020 - Present

Epilepsy is a chronic neurological disorder characterized by recurrent seizures that affect over 50 million people worldwide, including more than 3.5 million in the United States. Seizures arise from a disrupted balance between excitation and inhibition. Although antiepileptic drugs (AEDs) remain the primary treatment to restore the excitation and inhibition balance, approximately 30% of patients experience drug-resistant epilepsy, highlighting the need for additional antiseizure medications. The Caenorhabditis elegans electroshock assay was developed in relative alignment with the rodent maximal electroshock seizure (MES) test, the gold standard for preclinical AED screening, provides a cost-effective platform for prescreening candidate AEDs.

This work …

Roux-En-Y Gastric Bypass Is Associated With Increased Intestinal Glucose Uptake In Humans, Florina Corpodean, Maryam Naseri, Michael Kachmar, Julia St Amant, Denis P. Blondin, Owen T. Carmichael, Vance L. Albaugh

School of Medicine Faculty Publications

CONTEXT: In animal models, Roux-en-Y gastric bypass (RYGB) is associated with increased Roux limb intestinal glucose uptake that may contribute to early metabolic benefits, though prospective clinical studies are lacking. OBJECTIVE: The present study aimed to test the hypothesis that Roux limb glucose uptake would increase relative to baseline in a cohort of patients undergoing RYGB. METHODS: RYGB patients underwent preoperative baseline, and 3- and 6-month positron emission tomography/computed tomography postoperative imaging. Maximum and mean standardized uptake values (SUV) were measured from the following predefined regions of interest: cecum, hepatic flexure, splenic flexure, sigmoid colon, duodenal bulb, Roux limb, and …

Salvadora Persica’S Effects On Oral Microbiota And Possible Pathophysiological Links To Type Ii Diabetes Mellitus Risk Factors, Ahmed Bahieldin, Heba J. Sabbagh, Mohammed H Alshehri, Abdullah M. Algarni, Naif Aljahdali, Ibrahim M. Asir, Khalid Mohammed Alzahrani, Awad S. Almhwary, Fatemah Saleh Alzaghabi, Abdullah Jaber Alsahafi, Amjed S Alshehri, Ali Ahmed Alzahrani, Faisal M. Alotaibi, Mohammed A. Alghamdi, Abdulwahab S. Almutairi, Sherif Edris

The Journal of King Abdulaziz University: Science

The application of Miswak (Salvadora persica) in healthy children was investigated to identify the oral microbiota associated with risk factors for type II diabetes mellitus (T2DM). Deep sequencing of the bacterial 16S rDNA V3–V4 regions was conducted on oral microbiome samples obtained prior to and following swaking. The KEGG database and PICRUSt analysis indicated that swaking affected functional pathways, resulting in an enrichment of transport pathways and a decrease in the risk factor associated with the T2DM pathway. Seven operational taxonomic units (OTUs), comprising the uncharacterized species Prevotella, Atopobium, Actinomyces, Lactobacillus, Neisseria bacilliformis, Actinomycetaceae, …

Bilateral Hypoglossal Nerve Stimulation For Obstructive Sleep Apnea: A Nonrandomized Clinical Trial, B. Tucker Woodson, David T. Kent, Colin Huntley, Melyssa K Hancock, Douglas J. Van Daele, Maurits S. Boon, Tod C. Huntley, Sam Mickelson, M. Boyd Gillespie, Maria V. Suurna, Ashutosh Kacker, Asim Roy, Stuart Mackay, Kirk P. Withrow, Raj C. Dedhia, Phillip Huyett, Clemens Heiser, Sylvie Di Nicola, Fatima Makori, Olivier M. Vanderveken, Tapan A. Padyha, Ulysses J. Magalang, Eugene Chio, Eric J. Kezirian, Richard Lewis

Department of Otolaryngology - Head and Neck Surgery Faculty Papers

Study Objectives: To evaluate the safety and efficacy of a novel bilateral hypoglossal nerve stimulation (HNS_BL) device for the treatment of obstructive sleep apnea.

Methods: Adult patients with moderate-to-severe obstructive sleep apnea who refused, failed, or did not tolerate positive airway pressure therapy underwent implantation and nightly use of HNS_BL. The coprimary endpoints at 12 months were (1) a minimum of 50% reduction in the 4% apnea-hypopnea index (AHI) from baseline with a final AHI of less than 20 events/h, and (2) a minimum of 25% reduction in the 4% oxygen desaturation index. Objective secondary endpoints …

Mechanisms Matter, Nicole L. Collins, Kenneth S. Campbell

Physiology Faculty Publications

No abstract provided.

Six Drivers Of Aging Identified Among Genes Differentially Expressed With Age, Ariella Coler-Reilly, Zachary Pincus, Erica L Scheller, Roberto Civitelli

2020-Current year OA Pubs

Many studies have compared gene expression in young and old samples to gain insights on aging, the primary risk factor for most chronic diseases. However, these studies only identify associations without distinguishing drivers of aging from compensatory geroprotective responses or incidental downstream effects. Here, we introduce a workflow to characterize causal effects of differentially expressed genes on lifespan. First, we performed a meta-analysis of 25 gene expression datasets comprising samples of various tissues from healthy, untreated adult mammals (humans, dogs, and rodents) at two distinct ages. Genes were ranked by the number of datasets in which they exhibited consistent differential …

The Role Of Psilocybin In End-Of-Life Care: Evidence, Mechanisms, And Guidelines, Mackenzie E. Unsworth, Mary Lou Galantino, Robert Sandoval

Oncology Rehabilitation in Practice

This article aims to provide a brief overview of the evidence and mechanisms for psilocybin use in EOL care. Additionally, this article will provide guidelines for clinicians to assess patient use and integrate psilocybin into their clinical practice with respect to its current legal status.

New Mode For 4 Mm Path Irradiation And One Side Detection At 0–180° For Cu (Ii)Ion Determination In Different Samples Using On-Line Continuous Flow Feed And Simplified, Sensitive, And Portable Photometer, Asma A. Gayed Al-Ani, Nagham S. Turkey Al-Awadie

Baghdad Science Journal

This study presents a rapid, sensitive, and straightforward approach for measuring Cu(II) ions using turbidity continuous flow injection analysis (CFIA) . The method involves reacting Cu(II) ion with calcium Ferro cyanide to produce a brown-red precipitate. To detect the attenuation of incident light as a result of collision on the surfaces of the precipitate particles, the analyzer NAG-SSP-5S-1D was used to measure turbidity at an angle (0–180°).

The linear range of Cu(II) measurements extends from 0.01 to 5 mmol.L^–1 with Correlation Coefficient of 0.9993 and R² % = 99.86 .The limit of detection (LOD) was determined to be …

High-Stakes Exams Inflate A Gender Gap And Contribute To Systematic Grading Errors In One Introductory Physics Series, David J. Webb, Cassandra Paul

Faculty Research, Scholarly, and Creative Activity

Previous research has suggested that changing the percentage of the course grade associated with exam grades in science, technology, engineering, and mathematics courses can change the gender gap in the course. It has also been shown that high-stakes assessments yield the lowest (relative) scores for female students. Previous research by the authors has shown that implementing retake exams can eliminate the gender gap in introductory physics courses. This paper explores several different hypotheses for why retake exams are associated with a zeroed gender gap. Two independent measurements comparing exams with different stakes are used in support of the argument that …

The Echo: October 20, 2025, Taylor University

2025-2026 (Volume 113)

No abstract provided.

Timbre — A Transcendent Paradox?, Eugenia Siegel Conte

Yale Journal of Music & Religion

Timbre, as ethnomusicologist Cornelia Fales writes, is “paradoxical” precisely because it is one of the most exacting processes in which the human body may sense and comprehend the source of a sound even as that comprehended sound is impossible to describe outside of metaphor or comparison. As one of the more recognizable qualities of sound but the most difficult to describe, timbre allows us to consider physical/emotional (affective) experiences of sound as a key aspect of faith and meditation. In this article, I examine physical-affective intersections of faith and meditation that often are key to praxes of worship, and show …

Bifusenet: A Multimodal Network For Estimating Blood Alcohol Concentration Via Bidirectional Hierarchical Fusion, Abdullah Tariq, Arooba Maqsood, Martin Masek, Syed Zulqarnain Gilani

Research outputs 2022 to 2026

Drunk driving remains a significant public safety challenge, demanding innovative alternatives to conventional methods such as field sobriety tests and breathalysers. Estimating a driver's level of intoxication through facial cues is particularly challenging due to the subtle and person-specific nature of alcohol-induced behaviours. In this paper, we present BiFuseNet, a 3D spatio-temporal multi-modal network designed to classify alcohol impairment levels into three categories: sober, moderate, and severe. Unlike prior approaches that rely on either uni-modal RGB video or hand-crafted facial features, our method exploits complementary physiological cues from RGB and infrared (IR) facial videos. We introduce a Bi-directional Hierarchical Fusion …

2009 - Appalachian Student Research Forum Program Booklet, Appalachian Student Research Forum, East Tennessee State University

Appalachian Student Research Forum

No abstract provided.

Foundations Of Artificial Intelligence In Healthcare Diagnostics: A Systematic Survey, Raghad Tariq Al-Hassani

Al-Esraa University College Journal for Engineering Sciences

Artificial Intelligence (AI) is becoming the cornerstone of the future of healthcare diagnostics, that has to ability to change the healthcare diagnostic landscape in terms of diagnostic accuracy, speed, and availability. This systematic review investigates the basic methods, tools, applications, and challenges involved in the integration of AI in diagnostic medicine. It emphasizes the using of machine learning models, deep learning networks (e.g., CNNs), NLP for clinical documentation, and smart computing infrastructures, such as edge device and IoMT. They are making possible real-time, data-driven decision making that is already at human-expert-level performance or, in some cases, even better (in the …

Impact Of Microplastics Contaminated Food And Beverages On Reproductive And Mental Health, Lala Opeyemi Titilayo, Adisa Ayomide Funmilayo, Adelowo Joy Motunrayo, Oladapo Jesutomi Eniola, Oyekanmi Bolape Adeola, Lala Olusegun Gbenga, Afolabi Opeyemi Olanike, Ajayeoba Titilayo Adenike, Morakinyo Adetoun Elizabeth, Oladipo Elijah Kolawole, Oyowvi Mega Obukohwo, Oyedepo Temitope Adenike

Folia Medica Indonesiana

Microplastics, defined as plastic particles smaller than 5 mm, have emerged as a global environmental pollutant resulting from widespread plastic waste. Increasing concerns have been raised regarding their potential contamination of food and beverages, which may pose health risks to humans. This review aimed to evaluate current literature focusing on potential reproductive and mental health risks associated with the consumption of microplastic-contaminated food and beverages. A comprehensive literature search was conducted using multiple databases and Boolean operators to identify peer-reviewed English-language articles published within the past thirteen years. The review included studies that addressed microplastics in food and beverages, their …

The Effect Of Fascicular Elastin On The Mechanical And Functional Properties Of Healthy, Damaged, And Healing Tendon, Shawn Pavey

McKelvey School of Engineering Graduate Student Theses & Dissertations

Mechanical properties of tendon are highly influenced by structural protein composition and microscopic sub-structures. Within the largest subunit of tendon, the fascicle, the role of the elastin protein remains understudied despite impressive extensibility and fatigue resistance of its resulting elastic fibers. While previous work catalogued contributions of fascicular elastin across tendon type and species, the anticipated effects of elastin in fatigue and healing have not yet been explored. While previous knockout mouse models showed that disruption of elastic fibers led to altered mechanical properties (e.g., increased linear modulus), these models depended on heterozygous elastin deficiency or indirect knockout of proteins …

The Science Of Sound: Studying The Cognitive, Emotional, And Physiological Effects Of Frequency, Genre, And Music, Jett Yarborough

Senior Honors Theses

Music influences emotion, physiology, and cognition, yet little is known about how the frequency it is tuned to affects these influences. Prior research has shown that music tuned to 432 Hz can reduce stress, lower blood pressure, and improve sleep. My colleagues and I conducted two studies to investigate this. Our research found that music tuned to 432 Hz promotes a significant increase in memory retention and induces a state of focus and relaxation. These results suggest that shifting from the standard tuning frequency of 440 Hz to 432 Hz could have a profoundly positive impact on our daily lives. …

Check Out The Library, 2025 Fall Issue, Cal Poly Humboldt Library

Library Publications

Issue 20

Alternative Polyadenylation Contributes To Fibroblast Senescence In Pulmonary Fibrosis, Jingjing Huang, Maria Jose Gacha-Garay, Yu Wang, Scott D Collum, Rene A Girard, Hydia Puente, Seung-Hee Yoo, Rahat Hussain, Jayeshkumar Patel, Manish Patel, Eric J Wagner, Hari Krishnayalamanchili, Harry Karmouty-Quintana, Zheng Chen, Tingting Mills

Faculty, Staff and Students Publications

Idiopathic pulmonary fibrosis (IPF) is a prevalent and deadly age-related disease characterized by chronic, progressive, and irreversible fibrosis. A key effector cell population in the fibroproliferative response is the fibroblasts. Fibroblast cell senescence gradually worsens during aging, and the acquisition of a senescence-associated secretory phenotype (SASP) turns senescent fibroblasts into pro-inflammatory cells. However, the mechanism promoting senescence in IPF, especially at the post-transcriptional level, is poorly understood. We recently discovered that Nudix Hydrolase 21 (NUDT21, also named CFIm25), an RNA-binding protein, plays a critical role in regulating the expression of SASP factors through alternative polyadenylation (APA). APA allows adding poly(A) …