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Articles 1231 - 1260 of 79516
Full-Text Articles in Entire DC Network
Development Of Computational Imaging Pipelines To Advance Quantitative Co-Clinical Imaging And Pathology, Kaushik Dutta
Development Of Computational Imaging Pipelines To Advance Quantitative Co-Clinical Imaging And Pathology, Kaushik Dutta
McKelvey School of Engineering Graduate Student Theses & Dissertations
Deep learning driven computational methods have profoundly impacted medical imaging by advancing feature extraction, and by establishing a critical foundation for downstream image analysis and interpretation. Co-clinical trials are an emerging area of investigation in which a clinical trial is coupled with a corresponding preclinical study to inform the corresponding clinical trial to enhance translational accuracy and therapeutic development. Within this framework, quantitative imaging and pathology plays a fundamental role in both clinical and preclinical arms of co-clinical trials. Quantitative imaging enables enabling identification and validation of imaging biomarkers which are leveraged to predict therapeutic response, characterize disease phenotypes, and …
Quantitative Approaches To Dissect Bivalent Antibody Binding And Detect Viruses From Aerosolized Samples, Ananya Benegal
Quantitative Approaches To Dissect Bivalent Antibody Binding And Detect Viruses From Aerosolized Samples, Ananya Benegal
McKelvey School of Engineering Graduate Student Theses & Dissertations
Influenza A virus (IAV) poses substantial epidemiological burdens around the world, with an estimated annual global mortality rate in the hundreds of thousands. Its rapid rate of mutation gives it a propensity for causing seasonal epidemics and occasional pandemics. As an airborne virus, IAV is most commonly transmitted through droplets and aerosols. Antibodies play a crucial role in the immune defense against IAV infection. By understanding the mechanisms of antibody-mediated defense and the transmission dynamics of IAV, we can better inform strategies for prevention, vaccination, and treatment, ultimately mitigating its impact on public health. The work encompassed in this dissertation …
Bone-Ivd Crosstalk And The Role Of Rage Signaling In An Ivd Injury Model, Remy Walk
Bone-Ivd Crosstalk And The Role Of Rage Signaling In An Ivd Injury Model, Remy Walk
McKelvey School of Engineering Graduate Student Theses & Dissertations
Low back pain (LBP) is the number one musculoskeletal cause of disability with a lifetime prevalence of up to 85%. The causes of LBP are multifactorial with potential contributions from factors such as tissue injury and degeneration as well as social economic and psychological factors. Intervertebral disc (IVD) degeneration is associated with 26-40% of LBP cases and in a 2015 meta-analysis, it was estimated that a total 403 million people suffer from symptomatic IVD degeneration. IVD degeneration is characterized by loss of hydration in the nucleus pulposus (NP), damage accumulation in the annulus fibrosus (AF) and calcification of the cartilaginous …
Defining The Chondrocyte “Mechanome”: How Mechanosensitive Ion Channels Trpv4 And Piezo1 Drive Changes In Gene Expression To Affect Cell Behavior And Cartilage Health, Daniel Raymond Palmer
Defining The Chondrocyte “Mechanome”: How Mechanosensitive Ion Channels Trpv4 And Piezo1 Drive Changes In Gene Expression To Affect Cell Behavior And Cartilage Health, Daniel Raymond Palmer
McKelvey School of Engineering Graduate Student Theses & Dissertations
Chondrocytes, the only native cell population of cartilage, utilize mechanosensitive transmembrane ion channels to sense mechanical forces. Transient Receptor Potential Vanilloid 4 (TRPV4) is activated by physiologic levels of load (resulting in ~10% tissue deformation) while PIEZO1 is activated by supraphysiologic levels of load (resulting in >50% tissue deformation). TRPV4 activation promotes the expression of a limited number of chondrogenic genes and the production of vital cartilaginous matrix proteins, while PIEZO1 activation drives cell death and senescence, cytoskeletal weakening, and production of catabolic mediators, which contribute to the development of osteoarthritis (OA). However, the path connecting activation of these channels …
Developing Naturalistic Precision Functional Mapping For High-Density Diffuse Optical Tomography, Aahana Bajracharya
Developing Naturalistic Precision Functional Mapping For High-Density Diffuse Optical Tomography, Aahana Bajracharya
McKelvey School of Engineering Graduate Student Theses & Dissertations
Advancements in non-invasive imaging have enabled extensive research into higher-order cognitive functions of the brain. Functional Magnetic Resonance Imaging (fMRI) has provided valuable insights into brain networks underlying various cognitive processes. However, limitations such as confined environments and scanner noise pose challenges for fMRI to be broadly applicable across all demographics and experimental conditions, especially in speech and language studies. Because of this, there is a need for complementary techniques that can help understand the brain as it functions during everyday scenarios. High Density Diffuse Optical Tomography (HD-DOT) is an emerging functional near-infrared spectroscopy-based technique with comparative advantages over fMRI, …
Investigating Catalytic Conversion Of Lignin To Valuable Products, Jialiang Zhang
Investigating Catalytic Conversion Of Lignin To Valuable Products, Jialiang Zhang
McKelvey School of Engineering Graduate Student Theses & Dissertations
Lignin is a complex, random, and heterogeneous biopolymer in lignocellulosic biomass. It has significant potential for conversion into valuable chemicals and fuels. However, its natural recalcitrant structure has made selective depolymerization challenging. This dissertation presents a detailed investigation into the mechanisms of lignin disassembly and structural evolution under various catalytic and solvent conditions. The research spans three key studies. In Chapter 2, operando magic-angle spinning (MAS) solid-state nuclear magnetic resonance (NMR) spectroscopy was employed to study reaction pathways and kinetics of lignin model polymers during catalytic hydrogenolysis. We used a Ni-Al2O3 catalyst in methanol under high temperature and pressure, and …
Spatial Insight Of Kidney Sex-Dimorphism And Tumor Evolution, Chia-Kuei Mo
Spatial Insight Of Kidney Sex-Dimorphism And Tumor Evolution, Chia-Kuei Mo
McKelvey School of Engineering Graduate Student Theses & Dissertations
The landscape of spatial biology research has transformed drastically in recent years allowing a comprehensive understanding of cellular organization and molecular mechanisms in various biological context. This thesis presents three complementary studies that advance our understanding of spatial organization in normal tissue biology and tumor evolution, utilizing cutting-edge spatial multi-omics approaches. The first study presents a comprehensive investigation of kidney sexual dimorphism across the lifespan, integrating six distinct technological platforms: single-nucleus transcriptomics, epigenomics, Visium spatial transcriptomics, Xenium single-cell resolution spatial transcriptomics, conventional immunofluorescence imaging, and co-detection by indexing (CODEX) multiplexed protein imaging. This multi-modal approach reveals that proximal tubules exhibit …
Importance Of Social Support During Pregnancy For Girls With Limited Education, Mairo V. Bello
Importance Of Social Support During Pregnancy For Girls With Limited Education, Mairo V. Bello
Walden Dissertations and Doctoral Studies
Social support signifies a system that provides for family, relatives, and friends or is derived from external sources such as social services or health promotion networks and can reduce depression and increase well-being. Absent from the literature was the understanding of the significance of social support for young women with limited education aged 18-25 on the journey from conception to the postpartum period in Nigeria. In this qualitative phenomenological study, the individual perception, attitude, and social support received by young women with limited education during pregnancy in Wudil LGA of Kano state in northern Nigeria were examined. The study addressed …
Re-Indigenizing And Collaboratively Tending Urban Greenspaces, Divinity Nnenne Adewale
Re-Indigenizing And Collaboratively Tending Urban Greenspaces, Divinity Nnenne Adewale
University Honors Theses
This work details the active process of land tending with the intention of re-Indigenization in the Pacific Northwest at several Portland sites; The Native American Student Community Center, PSU Oak Savanna, and the Ridgefield National Wildlife Refuge. Land tending is an intuitive process, one rooted in love and respect for life of all forms as well as becoming the perpetual student; land tending is not a skill to be mastered, only practiced. Unlike environmental management, tending cannot be done separate from the earth, in a classroom or otherwise. Connections are what tending is built on top of: the foundation; effort …
From Sampling To Simulating: Single-Cell Multiomics In Systems Pathophysiological Modeling, Alexandra Manchel, Michelle M. Gee, Rajanikanth Vadigepalli
From Sampling To Simulating: Single-Cell Multiomics In Systems Pathophysiological Modeling, Alexandra Manchel, Michelle M. Gee, Rajanikanth Vadigepalli
Department of Pathology, Anatomy, and Cell Biology Faculty Papers
As single-cell omics data sampling and acquisition methods have accumulated at an unprecedented rate, various data analysis pipelines have been developed for the inference of cell types, cell states and their distribution, state transitions, state trajectories, and state interactions. This presents a new opportunity in which single-cell omics data can be utilized to generate high-resolution, high-fidelity computational models. In this review, we discuss how single-cell omics data can be used to build computational models to simulate biological systems at various scales. We propose that single-cell data can be integrated with physiological information to generate organ-specific models, which can then be …
Womb, Gravity, And Space: Shifting Towards The Cerebellum-Basal Ganglia Paradigm In Dystonia, Diego Iacono
Womb, Gravity, And Space: Shifting Towards The Cerebellum-Basal Ganglia Paradigm In Dystonia, Diego Iacono
Department of Neurology Faculty Papers
No abstract provided.
Promoting Confidence And Evidence-Based Practices For Attention-Deficit/Hyperactivity Disorder Among Integrated Primary Care Providers: A Qualitive Improvement Education Initiative, Omar Samateh, Margaret Emerson, Kayla Meisinger, Taylor Wilson, Leeza Struwe
Promoting Confidence And Evidence-Based Practices For Attention-Deficit/Hyperactivity Disorder Among Integrated Primary Care Providers: A Qualitive Improvement Education Initiative, Omar Samateh, Margaret Emerson, Kayla Meisinger, Taylor Wilson, Leeza Struwe
Doctor of Nursing Practice Projects: College of Nursing
Introduction: Primary Care Providers (PCPs) are seeing growing number of patients presenting for adult attention-deficit/hyperactivity disorder (ADHD) evaluations as a result of social media influences highlighting ADHD. Yet, PCPs report lacking confidence and education with adult ADHD. The purpose of this quality improvement study was to develop educational materials to promote confidence, competence, and adherence to ADHD evidence-based recommendations among integrated care PCPs. Methods: A literature review and retrospective chart review of 19 patients were used to create 1) Baseline ADHD Provider Education (PE) tool, 2) Standardized ADHD Diagnosis (SAD) referral process, 3) ADHD Assessment, Treatment, and Monitoring …
Bio-Preparedness In A Global Context: Multi-Site International Study Investigating Global Health Security Challenges In Egypt, Oman, And The United States, Rima M. Al Balushi
Bio-Preparedness In A Global Context: Multi-Site International Study Investigating Global Health Security Challenges In Egypt, Oman, And The United States, Rima M. Al Balushi
Theses & Dissertations
The COVID-19 pandemic exposed myriad vulnerabilities globally within public health systems, from inadequate bio-risk management in laboratories to overwhelming utilization of hospital resources and disparities in vaccine access and uptake. The Global Health Security Index (GHSI), which critically evaluates health security domains including health systems and risk environments, reports serious weaknesses in global health security. This dissertation aims to investigate critical aspects of global health security domains by examining factors impacting biosafety and biosecurity capacities in laboratories in Egypt, healthcare resource utilization in hospitals in Oman relating to acute respiratory infections (ARI), and COVID-19 vaccine uptake in the United States. …
Investigating Anomalous Experiences In Schizophrenia Spectrum Disorders, Pavan Brar
Investigating Anomalous Experiences In Schizophrenia Spectrum Disorders, Pavan Brar
Electronic Theses and Dissertations
The self-disorder model provides a phenomenological framework for understanding how the core symptoms of Schizophrenia Spectrum Disorders (SSDs) are rooted in an instability of minimal selfhood. This instability involves a range of ‘anomalous experiences’: transformations in an individual’s perceptual field and sense of being an agent of action. The explanatory value of this theoretical model can be summarized in two claims about the role of anomalous experiences in self-disorders: (1) anomalous experiences express a common trait-like disturbance that is characteristic of SSDs, and (2) anomalous experiences contribute to the progression of self-disorders into SSDs. Although hypotheses consistent with the first …
Novel Digital Anomalies, Hippocampal Atrophy, And Mutations Expand The Genotypic And Phenotypic Spectra Of Cnksr2 In The Houge Type Of X-Linked Syndromic Intellectual Development Disorder (Mrxshg), Mohammad Reza Ghasemi, Sahand Tehrani Fateh, Afif Ben-Mahmoud, Vijay Gupta, Lara G. Stühn, Gaetan Lesca, Nicolas Chatron, Konrad Platzer, Patrick Edery, Hossein Sadeghi, Bertrand Isidor, Benjamin Cogné, Heidi L. Schulz, Ilona Krauspe-Stübecke, Radhakrishnan Periyasamy, Sheela Nampoothiri, Reza Mirfakhraie, Sahar Alijanpour, Steffen Syrbe, Ulrich Pfeifer, Stephanie Spranger, Kathrin Grundmann-Hauser, Tobias B. Haack, Maria T. Papadopoulou, Tayrine Da Silva Gonçalves, Eleni Panagiotakaki, Alexis Arzimanoglou, Seyed Hassan Tonekaboni, Yves Lacassie, Et Al
Novel Digital Anomalies, Hippocampal Atrophy, And Mutations Expand The Genotypic And Phenotypic Spectra Of Cnksr2 In The Houge Type Of X-Linked Syndromic Intellectual Development Disorder (Mrxshg), Mohammad Reza Ghasemi, Sahand Tehrani Fateh, Afif Ben-Mahmoud, Vijay Gupta, Lara G. Stühn, Gaetan Lesca, Nicolas Chatron, Konrad Platzer, Patrick Edery, Hossein Sadeghi, Bertrand Isidor, Benjamin Cogné, Heidi L. Schulz, Ilona Krauspe-Stübecke, Radhakrishnan Periyasamy, Sheela Nampoothiri, Reza Mirfakhraie, Sahar Alijanpour, Steffen Syrbe, Ulrich Pfeifer, Stephanie Spranger, Kathrin Grundmann-Hauser, Tobias B. Haack, Maria T. Papadopoulou, Tayrine Da Silva Gonçalves, Eleni Panagiotakaki, Alexis Arzimanoglou, Seyed Hassan Tonekaboni, Yves Lacassie, Et Al
School of Medicine Faculty Publications
The Houge type of X-linked syndromic intellectual developmental disorder (MRXSHG) encompasses a spectrum of neurodevelopmental disorders characterized by intellectual disability (ID), language/speech delay, attention issues, and epilepsy. These conditions arise from hemizygous or heterozygous deletions, along with point mutations, affecting CNKSR2, a gene located at Xp22.12. CNKSR2, also known as CNK2 or MAGUIN, functions as a synaptic scaffolding molecule within the neuronal postsynaptic density (PSD) of the central nervous system. It acts as a link connecting postsynaptic structural proteins, such as PSD95 and S-SCAM, by employing multiple functional domains crucial for synaptic signaling and protein–protein interactions. Predominantly expressed in dendrites, …
Glucagon-Like Peptide-1 Receptor Agonist Mediated Weight Loss And Diabetes Mellitus Benefits: A Narrative Review, Alan D. Kaye, Nathan Lien, Christopher Vuong, Matthew H. Schmitt, Yusra Soorya, Bushirat A. Abubakar, Luke Muiznieks, Noah Embry, Harish Siddaiah, Adam M. Kaye, Sahar Shekoohi, Giustino Varrassi
Glucagon-Like Peptide-1 Receptor Agonist Mediated Weight Loss And Diabetes Mellitus Benefits: A Narrative Review, Alan D. Kaye, Nathan Lien, Christopher Vuong, Matthew H. Schmitt, Yusra Soorya, Bushirat A. Abubakar, Luke Muiznieks, Noah Embry, Harish Siddaiah, Adam M. Kaye, Sahar Shekoohi, Giustino Varrassi
School of Medicine Faculty Publications
Obesity and type 2 diabetes mellitus (T2DM) are chronic diseases with increasing prevalence, underscoring the urgent need for effective treatment and management strategies. Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have emerged as an essential class of drugs for managing both obesity and T2DM, offering additional benefits for cardiovascular and kidney health. GLP-1 RAs work by targeting GLP-1 receptors, mimicking the effects of the natural hormone GLP-1 to regulate blood glucose levels, promote weight loss, and provide potential benefits for cardiovascular health. This narrative review evaluates the mechanisms of action, clinical efficacy, and broader roles of GLP-1 RAs in promoting weight …
Beyond Bindis, Bhajis, Bangles And Bhangra: Promoting Multiculturalism In Primary Schools In Predominantly White British Places, Suparna Bagchi
Beyond Bindis, Bhajis, Bangles And Bhangra: Promoting Multiculturalism In Primary Schools In Predominantly White British Places, Suparna Bagchi
School of Law, Humanities and Social Sciences
Twenty-first-century education as a powerful means of knowledge will possibly be shaped by the emphasis it places on having classrooms that are race-conscious and multicultural. The present article is based on a doctoral study that explores an under-researched area: experiences and understanding of multiculturalism in mainstream primary schools situated in the predominantly White places of Southwest England. The study was underpinned by a sociocultural theoretical framework; data were collected through semi-structured interviews with the adult participants, students’ classroom activities, and documentary analysis of school displays. The article focuses on the data generated from the students’ classroom activities. Findings show differences …
Irregular Assessment Times In Pragmatic Randomized Clinical Trials, Andrea Apter, Frances K Barg, Sanjib Basu, Alex Federman, Winifred J Hamilton, Jerry A Krishnan, Tianjing Li, Russell Localio, Christine Pindle, Daniel O Scharfstein, Justin D Smith, Kaharu Sumino
Irregular Assessment Times In Pragmatic Randomized Clinical Trials, Andrea Apter, Frances K Barg, Sanjib Basu, Alex Federman, Winifred J Hamilton, Jerry A Krishnan, Tianjing Li, Russell Localio, Christine Pindle, Daniel O Scharfstein, Justin D Smith, Kaharu Sumino
Faculty, Staff and Students Publications
Deviation from protocolized assessment times is commonplace in pragmatic randomized clinical trials. Working with a stakeholder advisory board for a Patient-Centered Outcomes Research Institute®-funded project on statistical methods for handling potential biases introduced by irregular assessment times, we identified reasons for off-schedule or missed assessments. We used the Consolidated Framework for Implementation Research 2.0 to organize our findings. We conjectured that timely completion of outcome assessments is a function of multiple determinants, only some related to participants' health status. We identified potential determinants that can be modified during the protocol design stage and can be reassessed and mitigated during trial …
China’S Rare Earths Trade Flow Analysis: Trade Patterns And Strategic Insights, Linbin Tang, Peng Wang, Wei Chen, Yawen Han, Yuning Jin, Zilong Peng, Weiqiang Chen
China’S Rare Earths Trade Flow Analysis: Trade Patterns And Strategic Insights, Linbin Tang, Peng Wang, Wei Chen, Yawen Han, Yuning Jin, Zilong Peng, Weiqiang Chen
Bulletin of Chinese Academy of Sciences (Chinese Version)
Rare earth elements are strategic critical metals that support low-carbon energy, aerospace, and defense technologies. Currently, China’s rare earth industry lacks competitiveness and faces the risk of “multidimensional pressures” in global competition. Therefore, it is crucial to systematically analyze the supply-demand and trade patterns of rare earths, accurately identify the bottlenecks and pain points in China’s entire rare earth industry chain, and provide strategies to transform China’s rare earth resource advantage into a strategic competitive edge. Based on customs trade data, this study traces the trade flows of various forms of rare earth products across the full industry chain in …
Bile Acids In Inflammatory Bowel Disease: From Pathophysiology To Treatment, Samantha H Bai, Arun Chandnani, Siyan Cao
Bile Acids In Inflammatory Bowel Disease: From Pathophysiology To Treatment, Samantha H Bai, Arun Chandnani, Siyan Cao
2020-Current year OA Pubs
Inflammatory bowel disease (IBD) is a chronic condition that affects about 7 million people worldwide, and new therapies are needed. Understanding the complex roles that bile acids (BAs) play in IBD may lead to the development of novel IBD treatments independent of direct immunosuppression. This review discusses the latest discoveries in the roles BAs play in IBD pathogenesis and explores how these discoveries offer promising new therapeutic targets to treat IBD and improve patient outcomes. Several therapies discussed include specific BA receptor (BAR) agonists, dietary therapies, supplements, probiotics, and mesenchymal stem cell therapies that have all been shown to decrease …
Re: Approval Letter For The Butte Priority Soils Operable Unit (Bpsou) Unreclaimed Sites And Insufficiently Reclaimed Areas – Racetrack Borrow Material Usage (Dated December 19, 2024), Molly Roby
Silver Bow Creek/Butte Area Superfund Site
No abstract provided.
Ifrd1 Is Required For Maintenance Of Bladder Epithelial Homeostasis, Bisiayo E Fashemi, Amala K Rougeau, Arnold M Salazar, Steven J Bark, Rayvanth Chappidi, Jeffrey W Brown, Charles J Cho, Jason C Mills, Indira U Mysorekar
Ifrd1 Is Required For Maintenance Of Bladder Epithelial Homeostasis, Bisiayo E Fashemi, Amala K Rougeau, Arnold M Salazar, Steven J Bark, Rayvanth Chappidi, Jeffrey W Brown, Charles J Cho, Jason C Mills, Indira U Mysorekar
Faculty, Staff and Students Publications
The maintenance of homeostasis and rapid regeneration of the urothelium following stress are critical for bladder function. Here, we identify a key role for IFRD1 in maintaining urothelial homeostasis in a mouse model. We demonstrate that the murine bladder expresses IFRD1 at homeostasis, particularly in the urothelium, and its loss alters the global transcriptome with significant accumulation of endolysosomes and dysregulated uroplakin expression pattern. We show that IFRD1 interacts with mRNA-translation-regulating factors in human urothelial cells. Loss of Ifrd1 leads to disrupted proteostasis, enhanced endoplasmic reticulum (ER stress) with activation of the PERK arm of the unfolded protein response pathway, …
Rna-Dependent Rna Polymerase Of Predominant Human Norovirus Forms Liquid-Liquid Phase Condensates As Viral Replication Factories, Soni Kaundal, Ramakrishnan Anish, B Vijayalakshmi Ayyar, Sreejesh Shanker, Gundeep Kaur, Sue E Crawford, Jeroen Pollet, Fabio Stossi, Mary K Estes, B V Venkataram Prasad
Rna-Dependent Rna Polymerase Of Predominant Human Norovirus Forms Liquid-Liquid Phase Condensates As Viral Replication Factories, Soni Kaundal, Ramakrishnan Anish, B Vijayalakshmi Ayyar, Sreejesh Shanker, Gundeep Kaur, Sue E Crawford, Jeroen Pollet, Fabio Stossi, Mary K Estes, B V Venkataram Prasad
Faculty, Staff and Students Publications
Many viral proteins form biomolecular condensates via liquid-liquid phase separation (LLPS) to support viral replication and evade host antiviral responses, and thus, they are potential targets for designing antivirals. In the case of nonenveloped positive-sense RNA viruses, forming such condensates for viral replication is unclear and less understood. Human noroviruses (HuNoVs) are positive-sense RNA viruses that cause epidemic and sporadic gastroenteritis worldwide. Here, we show that the RNA-dependent RNA polymerase (RdRp) of pandemic GII.4 HuNoV forms distinct condensates that exhibit all the signature properties of LLPS with sustained polymerase activity and the capability of recruiting components essential for viral replication. …
Sisa's Vengeance: Rizal And The Mother Of All Insurgencies, E. San Juan Jr.
Sisa's Vengeance: Rizal And The Mother Of All Insurgencies, E. San Juan Jr.
Kritika Kultura
A new appraisal of Rizal is needed today in the light of 9/11, the collapse of finance capital, state terrorism, and neoliberal decadence and barbarism. Rizal’s revolutionary critique can be discovered by shifting the center of inquiry to the Dapitan years and after, the Liga’s resonance, and the Sisa-Maria Clara-Salome nexus. By exposing the limits of Simoun’s romantic idealism, Padre Florentino’s eschatological impulse, and the carnivalesque colonial world bereft of god/nomos, Rizal anticipates the post-capitalist predicament. Women’s vengeance against patriarchal nihilism lies submerged in Rizal’s communicative action to the Malolos collective, mobilizing emergent and residual historical forces in a dialectical …
Decolonizing Knowledges: Asian American Studies, Carlos Bulosan, And Insurgent Filipino Diasporic Imagination, Jeffrey Arellano Cabusao
Decolonizing Knowledges: Asian American Studies, Carlos Bulosan, And Insurgent Filipino Diasporic Imagination, Jeffrey Arellano Cabusao
Kritika Kultura
The current wars in Iraq and Afghanistan have compelled interdisciplinary scholars to seek new methods of engaging US Empire. This essay will attempt to outline an emerging critique-al strand of Filipino Cultural Studies that challenges the limitations of the “cultural turn” through its connection to the larger goal of creating movements for social justice. Over the past few years, new forms of Filipino American scholarship have advanced a unique tradition of class analysis developed by earlier generations of Filipino cultural workers and activists. In addition to this new development, Filipino American cultural workers have created politically conscious art through their …
Childhood And Family In Contemporary Children's Fiction: Resilience, Agency, And Emergence Of New Gender Norms, Rosario Torres-Yu
Childhood And Family In Contemporary Children's Fiction: Resilience, Agency, And Emergence Of New Gender Norms, Rosario Torres-Yu
Kritika Kultura
New awareness of re-thinking childhood in the emergent field of childhood studies inspires production of new discourse on social construction of childhood in literature. This paper looks at contemporary children’s literature in the Philippines from this perspective and within the context of the globalization and transnationalization of care giving. Its interrogation of selected children’s books and literature for young adult reveals that the traditional concept of childhood is now being challenged and resisted. Cognizant of the need to sustain this direction of literary production, this paper posits that children’s literature in the country should mainstream this new thinking so that …
Global Feminisms And The Polish "Woman": Reading Popular Culture Representations Through Stories Of Activism Since 1989, Magdalena J. Zaborowska, Justine M. Pas
Global Feminisms And The Polish "Woman": Reading Popular Culture Representations Through Stories Of Activism Since 1989, Magdalena J. Zaborowska, Justine M. Pas
Kritika Kultura
This article examines ten interviews with Polish feminist activists conducted by the Women’s Center “eFka” in Kraków and gathered by the Global Feminisms Project at the Institute for Research on Women and Gender at the University of Michigan in Ann Arbor. Employing intersectional and interdisciplinary approaches, it reads this collection in the context of Polish discourses on womanhood and femininity following the post-communist transition of 1989. The interviews offer a unique perspective on gender formations and invite us to think of the Other Europe beyond the clash of approaches to the region that have positioned it between the extremes of …
Gpr-185 A Multimodal Approach To Quiz Generation: Leveraging Rag Models For Educational Assessments, Mourya Teja Kunuku
Gpr-185 A Multimodal Approach To Quiz Generation: Leveraging Rag Models For Educational Assessments, Mourya Teja Kunuku
C-Day Computing Showcase
Crafting quiz questions that effectively assess students’ understanding of lectures and course materials, such as textbooks, poses significant challenges. Recent AI-based quiz generation efforts have predominantly concentrated on static resources, like textbooks and slides, often overlooking the dynamic and interactive elements of live lectures—contextual cues, discussions, and interactions—that contribute to the learning experience. In this work, we propose a Retrieval-Augmented Generation (RAG) model that processes multimodal inputs by combining text, audio, and video to produce quizzes that capture a fuller context. Our method incorporates Whisper for audio transcription and utilizes a Large Vision-Language Model (LVLM) to extract essential visual data …
Private Governance Comes Of Age: Vandenbergh, Light & Salzman’S Private Environmental Governance, Robert V. Percival
Private Governance Comes Of Age: Vandenbergh, Light & Salzman’S Private Environmental Governance, Robert V. Percival
Vanderbilt Law Review En Banc
No abstract provided.
Clinical Applications Of Phenomenology: Analysis Of Lived Experience Of Eye Disease, Kimberly Tucker
Clinical Applications Of Phenomenology: Analysis Of Lived Experience Of Eye Disease, Kimberly Tucker
Graduate Student Research Symposium
This paper presents a phenomenological study that explores the embodied experience of vision loss within the context of eye disease, while also providing a detailed discussion of the methodological approaches utilized in the research. Phenomenology is integrated to address clinical epistemic concerns, particularly the limitations of conventional vision tests in fully capturing perception and the lived experiences of vision loss. This interdisciplinary approach builds on the clinical understanding of eye disease by incorporating the broader dimensions of the lifeworld that intersect with visual impairment in degenerative eye diseases. While standard clinical approaches focus primarily on measurable aspects of visual function, …