Digital Commons Network^™

Evangelism As Worship: Instead Of Working "For God," Engaging In Ministry "To God", Marilyn Draper

Witness

No abstract provided.

An Evangelical Theology Of Engagement With Religious Others, Michael Urton

Witness

No abstract provided.

Clinicians As Researchers, Rolando T. Lazaro, Esmerita Rotor, Arvie C. Vitente, Catherine Joy T. Escuadra, Jocel M. Regino, Carmina L. Rafael

Philippine Journal of Physical Therapy

No abstract provided.

Postgraduate Medical Trainees At A Ugandan University Perceive Their Clinical Learning Environment Positively But Differentially Despite Challenging Circumstances: A Cross-Sectional Study, Paul E. Alele, Joshua Kiptoo, Kathleen Hill-Besinque

Pharmacy Faculty Articles and Research

Purpose

The clinical learning environment is an essential component in health professions’ education. Data are scant on how postgraduate trainees in sub-Saharan Africa perceive their medical school learning environments, and how those perceptions contribute to their engagement during training, their emotional wellbeing, and career aspirations. This study examined perceptions of postgraduate medical trainees (residents) in a resource-limited setting, regarding their learning environment and explored perceptual contributions to their career engagement during training. The data reported contribute to understanding how clinical learning environments can be improved in low-resource settings in Uganda and elsewhere.

Methods

This study was done at the Faculty …

Functionalized Surface Of Plga Nanoparticles In Thermosensitive Gel To Enhance The Efficacy Of Antibiotics Against Antibiotic Resistant Infections In Endodontics: A Randomized Clinical Trial, Mona Arafa, Hadeel Moussa, Mohamed Medhat Kataia

Pharmacy

Enterococcus faecalis plays the key role in endodontic infections and is responsible for the formation of biofilm on dentin, which causes a resistance against periradicular lesions treatment, consequently the aim of this study is to use nanoparticles entrapping anibacterial agents coated with chitosan that in authors previous study showed a successful in vitro biofilm inhibition, additionally incorporated in thermoresponsive gel.to benefit nanoparticles` small size, and the positive charge of their surfaces that binds with the negatively charged surface of bacterial cell causing its destruction, in addition to the sustained release pattern of the drug based nanoparticles in gel. Therefore, Ciprofloxacin …

Understanding The Relationship Between Narcissism And Political Orientations In College-Aged Adults, Sabrina Richards

Undergraduate Honors Theses

When you try to guess someone’s political beliefs, you probably look towards the usual culprits: race, gender, education, religion, age, marital status, and more. Have you ever tried looking at their narcissistic tendencies? There are seven different types of narcissism, and in a study conducted by Peter K. Hatemi and Zoltan Fazekas in 2018, it was revealed that there is a relationship between an adult’s narcissistic personality traits and their political orientations. It was observed that entitlement narcissism is associated with more conservative political orientations, while exhibitionism narcissism is associated with more liberal political orientations. However, there is a lack …

Protocol For An Agent-Based Model Of Recombination In Bacteria Playing A Public Goods Game, Isaiah Paolo A. Lee, Omar T. Eldakar, J. Peter Gogarten, Cheryl P. Andam

Biology Faculty Articles

Agent-based models are composed of individual agents coded for traits, such as cooperation and cheating, that interact in a virtual world based on defined rules. Here, we describe the use of an agent-based model of homologous recombination in bacteria playing a public goods game. We describe steps for software installation, setting model parameters, running and testing models, and visualization and statistical analysis. This protocol is useful in analyses of horizontal gene transfer, bacterial sociobiology, and game theory.

For complete details on the use and execution of this protocol, please refer to Lee et al.¹

Toughness Of Recursively Partitionable Graphs, Calum Buchanan, Brandon Du Preez, K. E. Perry, Puck Rombach

Theory & Applications of Graphs

A simple graph G = (V,E) on n vertices is said to be recursively partitionable (RP) if G ≃ K1, or if G is connected and satisfies the following recursive property: for every integer partition a₁, a₂, . . . , a_k of n, there is a partition {A₁,A₂, . . . ,A_k} of V such that each |A_i| = a_i, and each induced subgraph G[A_i] is RP (1 ≤ i ≤ k). We show that if S is a …

Optimizing Sepsis Management Through Enhanced Protocol Compliance In The Emergency Department, Oscar J. Castillo

Master's Projects and Capstones

Problem: The Quality Improvement (QI) Project focused on improving early sepsis management and sepsis bundle adherence among Emergency Department (ED) nurses to decrease sepsis mortality rates and avoidable length of hospital stays (LOS).

Context: A group of Clinical Nurse Leaders (CNL) students evaluated sepsis protocol compliance at Hospital A's ED, which provides critical care for patients with various medical conditions. The CNL students concentrated on patients identified with sepsis for the QI Project.

Interventions: Limitations and time did not allow for the implementation of interventions. Recommendations offered to management included increasing sepsis training biannually and intravenous placement skills, offering sepsis …

Improving Early Sepsis Recognition: Resocializing Intensive Care Unit Nurses In A Large Hospital On The Inpatient Sepsis Bundle Checklist, Nancy Zhu

Master's Projects and Capstones

Problem: Sepsis is a life threatening disease that has caused over a million deaths annually in the nation. Early recognition of sepsis is highly crucial for health care professionals to know to prevent an increase of mortality and morbidity rates. This quality improvement project aimed to increase sepsis bundle checklist awareness to the staff and compliance in the Intensive Care Unit to improve the sepsis cases.

Context: Clinical Nurse Leader students completed a microsystem assessment of the Intensive Care Unit at Hospital X in San Mateo County. This unit cares for patients with sepsis, septic shock, severe sepsis, organ failure, …

A Virtual Reality Conditioned Place Preference In Undergraduates With Nicotine Use, Lukas Klin

Honors Scholar Theses

This study was conducted to determine if a Conditioned Place Preference (CPP) could be established for a Virtual Reality (VR) environment that was previously paired with virtual nicotine stimuli. 254 undergraduate students with varying levels of nicotine use from the University of Connecticut were recruited to participate in the study. Participants completed six, three-minute conditioning sessions where they were confined to one of two VR rooms with one room containing virtual nicotine stimuli while the other was neutral. Participants then completed a three-minute test session, in which they were allowed access to both rooms and there were no virtual nicotine …

Invited Commentary On The Development And Initial Validation Of The Pain Progress Measure, Oliver Ang

Philippine Journal of Physical Therapy

No abstract provided.

Author’S Response To Ang, O. Invited Commentary On The Development And Initial Validation Of The Pain Progress Measure, Adnan N. Balisi

Philippine Journal of Physical Therapy

No abstract provided.

Interrogation Of The Molecular Mechanisms That Finetune Fcεri Signaling And Mast Cell Outcomes, Derek A. Rinaldi

Biomedical Sciences ETDs

FcεRI is the ITAM receptor primarily responsible for the allergic response and immune hypersensitivity diseases such as asthma. Regulation of the strength of both FcεRI signaling, and the resulting outcomes, is accomplished via a complex array of molecular mechanisms whose interactions remain unclear. Here, I explored how the biophysical properties of antigens, crosstalk between FcεRI and integrin signaling and Arf6-mediated control of trafficking and exocytosis tune mast cell outcomes. I first found significant differences in FcεRI aggregation, phosphorylation and granule secretion after crosslinking with the multivalent antigen DNP-BSA or the small, trivalent antigen DF3. I also revealed a bi-directional, Syk-mediated …

Introduction To Physics, Kalani Hetti

Open Educational Resources

Introduction to physics, class code PHY 114 at college of Staten Island covers general physics concepts by using very simple algebraic calculations. Topics may include scientific measurements, significant figures, estimation, units, linear and rotational motion, vectors, forces, energy, momentum, collision, impulse, projectile motion, circular motion, thermodynamics, oscillating waves, electricity and magnetism, properties of lights, reflection, refraction, atomic nuclei, and radioactivity. This course is designed to teach general concepts and laws of physics to everyday life enforcing student’s critical thinking, logical patterns, organization, and everyday life applications. In this document, all the class materials including lectures, worksheets, homework assignments, quizzes, and …

Impact Of Ict Sector Research And De Velopment Expenditure On The Market Capitalization In The Us, The Eu And China, Wojciech Chmielewski

Studia i Materiały Wydział Zarządzania Uniwersytet Warszawski

Purpose: Due to the growing global role of enterprises from the information and communication technology sector from the leading regions of the USA, EU and China in the industry, the author’s research goal was to try to identify factors influencing the value of listed enterprises understood as its stock exchange capitalization. For the purpose, research was carried out on the impact of a group of twenty-six variables on the company’s market capitalization, among which the most important conclusions concern the impact of seven variables, i.e. revenues, research and development expenses, earnings before interest, taxes, depreciation and amortization (EBITDA), earnings before …

Tipping The Mesoscales: Advances In Multipeak Bragg Coherent Diffraction Imaging, J. Nicholas Porter

Theses and Dissertations

Material failure begins with strain between atoms and cascades upward into macroscopic damage such as cracks. Therefore, our ability to predict (and therefore prevent) material failure is largely limited by our understanding of this process. This understanding, however, has been impeded by the difficulty of directly observing such phenomena. In this thesis, I discuss recent advances in Bragg coherent diffraction imaging (BCDI) which produce three-dimensional, mesoscopic images of interior strain in microcrystals. In particular, I present a novel algorithm, based on the concept of cyclic-constrained optimization (CCO), for the rapid, coupled reconstruction of a microcrystal from multiple Bragg diffraction patterns. …

Pkcε Activator Protects Hippocampal Microvascular Disruption And Memory Defect In 3×Tg-Alzheimer's Disease Mice With Cerebral Microinfarcts, Huaixing Wang, Zongxiu Zhang, Jarin Hongpaisan

Center for Translational Medicine Faculty Papers

BACKGROUND: Current evidence suggests that microvessel disease is involved in Alzheimer's disease (AD). Cerebrovascular disease correlates with cardiovascular disease and is complicated in ≈40% of AD patients. The protein kinase C (PKC) ε activator DCPLA can stimulate human antigen (Hu) R that prevents degradation and promotes the translation of mitochondrial Mn-superoxide dismutase (MnSOD) and vascular endothelial growth factor-A (VEGF) mRNAs.

METHODS: To induce brain microinfarcts, we injected triple transgenic (3×Tg) and wild-type (WT) control mice with microbeads (20 μm caliber) into common carotid arteries, with or without the DCPLA-ME (methyl-ester) for 2 weeks. After water maze training, mice at 16 …

Paradas: Utilizing The Organizational Structure Of Spatial Agency In Migrant Labor Posts, Erik Duque

Theses

Sustainability is a subject dominated by topics involving the environment and economy. An overlooked pillar is that of the socio-political sphere, as it is a subgenre of sustainability that involves a wide range of variables. Fortunately, there exists a multitude of ways one can relieve social tensions, but unfortunately, as socio-political issues are much more complex to measure. Our current Latin/US-based issues are rooted in racism, colonialization, and imperialism. These past wrongs have affected Latin American countries' development in that corruption, economic instability, violence, lack of education and poverty are the outcomes that push people into migrating. Latin American migrants …

Unsupervised Multi-Resolution Analysis Of Protein-Protein Abundance Patterns In Infectious Exacerbation Of Copd, Eric Everingham

Theses

Despite consistently appearing as a top 5 cause of death domestically and internationally, understandings of the underlying biological interactions of COPD remain insufficient. Particularly, early identification of highly vulnerable patients that may experience more severe infectious exacerbation is a challenge during diagnostics. This project leverages unsupervised clustering and multi-resolution decomposition of proteomic abundance profiles in a small cohort of COPD subjects to identify candidate biomarkers of heightened exacerbation risk. As part of an ongoing study, serum and sputum samples were collected during well visits (stable illness) from n=67 subjects, and analyzed using quantitative proteomics. A scores principal component analysis was …

Retreat Village Design In Letchworth State Park Region: An Architecture Development In A Highly Valued State Park Meets The Triple Bottom Line Of Sustainability, Jing Hua

Theses

Letchworth State Park, located in Livingston and Wyoming counties, New York, renowned as the “Grand Canyon of the East”, is one of the most scenically magnificent areas in the eastern United States. However, there are no well-developed leisure centers around or in the park. The lack of good accommodations, in contrast to the availability of restaurants with local character, leisure activities, and other supporting facilities in the area, fails to fully achieve the development potential of the natural scenery of the region. This thesis demonstrates that a retreat complex village that brings people closer to the natural landscape of Letchworth …

Thermodynamics Of Ice Arena Geometry, Low- Emissivity Of Building Materials, And Natural Ventilation: An Energy Efficiency Study Of An Ice Arena In Rochester, Ny, Jonathan Sutton

Theses

This thesis explores the thermodynamic relationship between an ice arena’s ice sheet and building form. This exploration was conducted through an experiment focusing on the effects of architectural geometry, building material, and natural ventilation on ice heat gain. Ice arenas are giant refrigeration systems meant to sustain a sheet of ice in any climate, which is energy-intensive. There are many mechanical solutions to improving energy efficiency within ice arenas, leaving a gap for architectural solutions. Thermodynamics is how heat transfers or moves between space or objects. Heat or temperature wants to reach equilibrium, which means cold surfaces, objects, or air …

Performance Evaluation Of Residential Design In Four Different Climate Zones Using Passive House Strategies And Metrics, Ian Luhmann

Theses

This study presents a comprehensive performance evaluation of residential designs across four different climate zones, employing Passive House strategies and metrics to achieve energy efficiency, comfort, and sustainability. The Passive House standard, recognized for its rigorous approach to energy-efficient buildings, is the cornerstone of this research. The objective is to adapt and optimize residential designs to meet the specific climate conditions of each zone while adhering to the Passive House principles and noting the modifications necessary to do so.

Convicting The Innocent: The Impact Of Wrongful Conviction In The U.S. Criminal Legal System, Aubrie Entwood

Theses

Wrongful conviction is a justice system error with far-reaching consequences. This capstone project looks at four different issues within wrongful conviction and exoneration in the U.S. criminal legal system. Chapter 1 focuses on the impacts of wrongful conviction for female exonerees, highlighting the way they are different from male exonerees, the factors that contribute to wrongful conviction that are more salient to females, and the specific ways the police and courts contribute to the wrongful conviction of females. Special attention is paid to the “crimes” of female exonerees and the additional psychological consequences that many female exonerees suffer. Ways in …

Middle-Earth, Or There And Back Again, Edited By Łukasz Neubauer. Reviewed By Hamish Williams., Hamish Williams

Mythprint Book Reviews

Mythprint is the quarterly bulletin of the Mythopoeic Society, a nonprofit educational organization devoted to the study, discussion, and enjoyment of myth and fantasy literature, especially the works of J.R.R. Tolkien, C.S. Lewis, and Charles Williams. To promote these interests, the Society publishes three magazines, maintains a World Wide Web site, and sponsors the annual Mythopoeic Conference and awards for fiction and scholarship, as well as local discussion groups.

Metformin Alleviates Hepatic Iron Overload And Ferroptosis Through Ampk-Ferroportin Pathway In Hfd-Induced Nafld, Fangzhi Yue, Ying Shi, Shanyu Wu, Lin Xing, Dan He, Lin Wei, Anqi Qiu, Ryan D. Russell, Dongmei Zhang

Health & Human Performance Faculty Publications

Highlights

• Metformin alleviates HIO and ferroptosis in HFD-induced NAFLD

• FPN is involved in the molecular mechanism of metformin on HIO in HFD-induced NAFLD

• Metformin upregulates FPN expression by reducing lysosomal ubiquitination degradation

Summary

Metformin prevents progression of non-alcoholic fatty liver disease (NAFLD). However, the potential mechanism is not entirely understood. Ferroptosis, a recently recognized nonapoptotic form of regulated cell death, has been reported to be involved in the pathogenesis of NAFLD. Here, we investigated the effects of metformin on ferroptosis and its potential mechanism in NAFLD. We found that metformin prevented the progression of NAFLD, and alleviated hepatic iron …

Metformin Alleviates Hepatic Iron Overload And Ferroptosis Through Ampk-Ferroportin Pathway In Hfd-Induced Nafld, Fangzhi Yue, Ying Shi, Shanyu Wu, Lin Xing, Dan He, Lin Wei, Anqi Qiu, Ryan D. Russell, Dongmei Zhang

Health & Human Performance Faculty Publications

Highlights

• Metformin alleviates HIO and ferroptosis in HFD-induced NAFLD

• FPN is involved in the molecular mechanism of metformin on HIO in HFD-induced NAFLD

• Metformin upregulates FPN expression by reducing lysosomal ubiquitination degradation

Summary

Metformin prevents progression of non-alcoholic fatty liver disease (NAFLD). However, the potential mechanism is not entirely understood. Ferroptosis, a recently recognized nonapoptotic form of regulated cell death, has been reported to be involved in the pathogenesis of NAFLD. Here, we investigated the effects of metformin on ferroptosis and its potential mechanism in NAFLD. We found that metformin prevented the progression of NAFLD, and alleviated hepatic iron …

Gpr84-Mediated Signal Transduction Affects Metabolic Function By Promoting Brown Adipocyte Activity, Xue-Nan Sun, Yu A An, Vivian A Paschoal, Camila O De Souza, May-Yun Wang, Lavanya Vishvanath, Lorena Ma Bueno, Ayanna S Cobb, Joseph A Nieto Carrion, Madison E Ibe, Chao Li, Harrison A Kidd, Shiuhwei Chen, Wenhong Li, Rana K Gupta, Da Young Oh

Faculty, Staff and Student Publications

The G protein-coupled receptor 84 (GPR84), a medium-chain fatty acid receptor, has garnered attention because of its potential involvement in a range of metabolic conditions. However, the precise mechanisms underlying this effect remain elusive. Our study has shed light on the pivotal role of GPR84, revealing its robust expression and functional significance within brown adipose tissue (BAT). Mice lacking GPR84 exhibited increased lipid accumulation in BAT, rendering them more susceptible to cold exposure and displaying reduced BAT activity compared with their WT counterparts. Our in vitro experiments with primary brown adipocytes from GPR84-KO mice revealed diminished expression of thermogenic genes …

Galonsky V. East 17th Llc

All Decisions

No abstract provided.

Panora V. Peterson

All Decisions

No abstract provided.