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Articles 5971 - 6000 of 35248
Full-Text Articles in Entire DC Network
Rangewide Migratory Connectivity And Migration Ecology In Swainson's Warblers (Limnothlypis Swainsonii) Derived From Multisensor Geolocators, Garrett Rhyne
LSU Master's Theses
Successful conservation of Neotropical migratory passerines requires a detailed understanding of their annual cycle ecology, including wintering and breeding distributions, migratory pathways and stopovers, and migratory phenology. It is also important to evaluate the extent of geographic isolation between separate breeding populations during the nonbreeding season, known as migratory connectivity. Swainson’s Warbler (Limnothlypis swainsonii) is a species of conservation concern that, due to their secretive nature and selection of dense forest habitats, is poorly studied and lacks migratory information. Our objective was to track Swainson’s Warblers across their breeding populations (Mississippi Valley, Coastal Plains, and Appalachian) to detail …
High-Dimensional Deconstruction Of Pancreatic Cancer Identifies Tumor Microenvironmental And Developmental Stemness Features That Predict Survival, Erik P Storrs, Prathamesh Chati, Abul Usmani, Ian Sloan, Bradley A Krasnick, Peter K Harris, Chloe M Sachs, Faridi Qaium, Chris Wetzel, S Peter Goedegebuure, Thomas Hollander, Hephzibah Anthony, Jennifer Ponce, Shahed Badiyan, Hyun Kim, David G Denardo, Gabriel D Lang, Natalie D Cosgrove, Vladimir M Kushnir, Dayna S Early, Kian-Huat Lim, William G Hawkins, Li Ding, Ryan C Fields, Koushik K Das, Aadel A Chaudhuri, Et Al.
High-Dimensional Deconstruction Of Pancreatic Cancer Identifies Tumor Microenvironmental And Developmental Stemness Features That Predict Survival, Erik P Storrs, Prathamesh Chati, Abul Usmani, Ian Sloan, Bradley A Krasnick, Peter K Harris, Chloe M Sachs, Faridi Qaium, Chris Wetzel, S Peter Goedegebuure, Thomas Hollander, Hephzibah Anthony, Jennifer Ponce, Shahed Badiyan, Hyun Kim, David G Denardo, Gabriel D Lang, Natalie D Cosgrove, Vladimir M Kushnir, Dayna S Early, Kian-Huat Lim, William G Hawkins, Li Ding, Ryan C Fields, Koushik K Das, Aadel A Chaudhuri, Et Al.
2020-Current year OA Pubs
Numerous cell states are known to comprise the pancreatic ductal adenocarcinoma (PDAC) tumor microenvironment (TME). However, the developmental stemness and co-occurrence of these cell states remain poorly defined. Here, we performed single-cell RNA sequencing (scRNA-seq) on a cohort of treatment-naive PDAC time-of-diagnosis endoscopic ultrasound-guided fine needle biopsy (EUS-FNB) samples (n = 25). We then combined these samples with surgical resection (n = 6) and publicly available samples to increase statistical power (n = 80). Following annotation into 25 distinct cell states, cells were scored for developmental stemness, and a customized version of the Ecotyper tool was used to identify communities …
The Montclarion, October 19, 2023, The Montclarion
The Montclarion, October 19, 2023, The Montclarion
The Montclarion
Student Newspaper of Montclair State University
Oregon State Rank Assessment For Oregon Spotted Frog (Rana Pretiosa), Misty Nelson
Oregon State Rank Assessment For Oregon Spotted Frog (Rana Pretiosa), Misty Nelson
Institute for Natural Resources Publications
Oregon state conservation status assessment for Oregon spotted frog (Rana pretiosa) using NatureServe methodology, 2023.
Biosynthesis Of Mgo Nanoparticles And Their Impact On The Properties Of The Pva/Gelatin Nanocomposites For Smart Food Packaging Applications, Mohamed Morsy
Nanotechnology Research Centre
No abstract provided.
A Study On The Factors Of Barriers To Female University Students' Sports Participation From An Environmental Perspective, Rongjing Ni, Ying Yu
A Study On The Factors Of Barriers To Female University Students' Sports Participation From An Environmental Perspective, Rongjing Ni, Ying Yu
Indonesian Journal of Research in Physical Education, Sport, and Health
Objective: To understand the barriers to sports participation of Chinese female university students and to increase their motivation to participate in sports. Methods: A survey of 1892 female undergraduates aged 18 to 22 who were enrolled in the university was conducted mainly by questionnaire method, and t-test and reliability analysis were conducted using SPSS, and validated factor analysis was conducted using Amos software. Results: Venue environment, natural environment and sports atmosphere are common strong perception factors, while interpersonal environment, social sports environment and policy environment are common weak perception factors. All indicators in the dimension of site environment and natural …
Ispring Application-Based Volleyball Game Learning Media Development, Ichwan Fauzi, Hariyoko Hariyoko
Ispring Application-Based Volleyball Game Learning Media Development, Ichwan Fauzi, Hariyoko Hariyoko
Indonesian Journal of Research in Physical Education, Sport, and Health
Background: Learning media is one of the essential factors in achieving learning objectives, so a subject requires appropriate learning media. Objective: This research aims to develop a volleyball game learning media for students in class VIII at State Junior High School 9 Malang. Methods: This research uses the Research and Development method ADDIE. As for the data collection instrument in the form of observation by directly observing learning activities in class VIII State Junior High School 9 Malang, namely learning volleyball games, the time is relatively short, so the teacher needs help giving students the material as a whole. Results: …
Critical Analysis Of Anti-Asian Hate In The News, Benardo Douglas Relampagos
Critical Analysis Of Anti-Asian Hate In The News, Benardo Douglas Relampagos
Dissertations and Theses
Since 2019, the United States has had an increase in violence against Asian American Pacific Islander (AAPI) communities along with an increase of mainstream anti-Asian racist rhetoric. Between 2021 and 2022, The Center for the Study of Hate & Extremism reported an overall 164% increase in anti-Asian hate crimes. While racism against black, Indigenous, people of color (BIPOC) communities has been the topic of an ever-growing body of critical discourse, prior to 2019 few publications had addressed racism and injustice regarding language choices and discourse in the context of anti-Asian rhetoric in the US, specifically regarding the intersection of language …
Synapse-Associated Protein 102 – A Highly Mobile Maguk Predominate In Early Synaptogenesis, Dominique Alexandra De Los Reyes, Mohammad Yaman Karkoutly, Yonghong Zhang
Synapse-Associated Protein 102 – A Highly Mobile Maguk Predominate In Early Synaptogenesis, Dominique Alexandra De Los Reyes, Mohammad Yaman Karkoutly, Yonghong Zhang
School of Integrative Biological & Chemical Sciences Faculty Publications
Neurodevelopmental and neurodegenerative disorders are primarily characterized by serious structural and functional changes in excitatory glutamatergic synapses in the brain, resulting in many synaptic deficits and aberrant synapse loss. It is a big challenge to reverse these synaptic impairments as a treatment for neurological diseases in the field. Extensive research on glutamate receptors as therapeutic targets has been done but with little success shown in human trials. PSD-95-like MAGUK proteins perform a pivotal role in regulating the trafficking and stability of glutamate receptors that are important to postsynaptic structure and function. MAGUK and MAGUK-modulated synaptic pathways are becoming promising candidates …
In Silico Prediction Of Sodium-Glucose Co-Transporter-2 (Sglt2) Inhibition Activity By Allium Fistulosum Compound Based On Skelspheres Molecular Descriptor, Rudy Heryanto, Aryo Tedjo, Dimas Noor
In Silico Prediction Of Sodium-Glucose Co-Transporter-2 (Sglt2) Inhibition Activity By Allium Fistulosum Compound Based On Skelspheres Molecular Descriptor, Rudy Heryanto, Aryo Tedjo, Dimas Noor
Indonesian Journal of Medical Chemistry and Bioinformatics
The Sodium-Glucose co-transporter-2 (SGLT2) inhibitor represents a novel agent for the treatment of type 2 diabetes. Drugs of this class function by inhibiting glucose reabsorption in the kidneys, thereby controlling blood glucose levels. It is known that SGLT2 inhibitors activate the AMPK signaling pathway by increasing the expression and activity of AMP-activated protein kinase (AMPK). In vivo tests have demonstrated that ethanolic and aqueous extracts of Welsh onion leaves (Allium fistulosum L) can reduce body weight, liver weight, adipocyte size, and enhance AMP-activated protein kinase (AMPK) expression. In this study, the inhibitory activity (IC50) of compounds within Allium fistulosum against …
Editorial: Stem Cells And The Immune System., John M. Perry, Meng Zhao
Editorial: Stem Cells And The Immune System., John M. Perry, Meng Zhao
Manuscripts, Articles, Book Chapters and Other Papers
No abstract provided.
The Effect Of Heat-Moisture Treatment Changed The Binding Of Starch, Protein And Lipid In Rice Flour To Affect Its Hierarchical Structure And Physicochemical Properties, Seung Hee Yoo, Mi Jin Jue, Yu-Hee Kim, Sooyoung Cho, Won-Joong Kim, Kye-Min Kim, Jong In Han, Heeseung Lee
The Effect Of Heat-Moisture Treatment Changed The Binding Of Starch, Protein And Lipid In Rice Flour To Affect Its Hierarchical Structure And Physicochemical Properties, Seung Hee Yoo, Mi Jin Jue, Yu-Hee Kim, Sooyoung Cho, Won-Joong Kim, Kye-Min Kim, Jong In Han, Heeseung Lee
Faculty, Staff and Student Publications
Dexmedetomidine prevents postoperative cognitive dysfunction by inhibiting high-mobility group box 1 (HMGB1), which acts as an inflammatory marker. This study investigated the HMGB1 levels and the cognitive function using a Mini-Cog© score in elderly patients undergoing orthopedic surgery with dexmedetomidine infusion. In total, 128 patients aged ≥ 65 years were analyzed. The patients received saline in the control group and dexmedetomidine in the dexmedetomidine group until the end of surgery. Blood sampling and the Mini-Cog© test were performed before the surgery and on postoperative days 1 and 3. The primary outcomes were the effect of dexmedetomidine on the HMGB1 levels …
Adaptive Design Of Mrna-Loaded Extracellular Vesicles For Targeted Immunotherapy Of Cancer, Shiyan Dong, Xuan Liu, Ye Bi, Yifan Wang, Abin Antony, Daeyong Lee, Kristin Huntoon, Seongdong Jeong, Yifan Ma, Xuefeng Li, Weiye Deng, Benjamin R Schrank, Adam J Grippin, Jonghoon Ha, Minjeong Kang, Mengyu Chang, Yarong Zhao, Rongze Sun, Xiangshi Sun, Jie Yang, Jiayi Chen, Sarah K Tang, L James Lee, Andrew S Lee, Lirong Teng, Shengnian Wang, Lesheng Teng, Betty Y S Kim, Zhaogang Yang, Wen Jiang
Adaptive Design Of Mrna-Loaded Extracellular Vesicles For Targeted Immunotherapy Of Cancer, Shiyan Dong, Xuan Liu, Ye Bi, Yifan Wang, Abin Antony, Daeyong Lee, Kristin Huntoon, Seongdong Jeong, Yifan Ma, Xuefeng Li, Weiye Deng, Benjamin R Schrank, Adam J Grippin, Jonghoon Ha, Minjeong Kang, Mengyu Chang, Yarong Zhao, Rongze Sun, Xiangshi Sun, Jie Yang, Jiayi Chen, Sarah K Tang, L James Lee, Andrew S Lee, Lirong Teng, Shengnian Wang, Lesheng Teng, Betty Y S Kim, Zhaogang Yang, Wen Jiang
Faculty, Staff and Student Publications
The recent success of mRNA therapeutics against pathogenic infections has increased interest in their use for other human diseases including cancer. However, the precise delivery of the genetic cargo to cells and tissues of interest remains challenging. Here, we show an adaptive strategy that enables the docking of different targeting ligands onto the surface of mRNA-loaded small extracellular vesicles (sEVs). This is achieved by using a microfluidic electroporation approach in which a combination of nano- and milli-second pulses produces large amounts of IFN-γ mRNA-loaded sEVs with CD64 overexpressed on their surface. The CD64 molecule serves as an adaptor to dock …
2023-10-19 Institutional Animal Care And Use Committee Meeting Minutes, Morehead State University. Faculty Senate., Institutional Animal Care And Use Committee.
2023-10-19 Institutional Animal Care And Use Committee Meeting Minutes, Morehead State University. Faculty Senate., Institutional Animal Care And Use Committee.
Faculty Senate Records
The meeting minutes of the Institutional Animal Care and Use Committee for October 19, 2023.
A Thesis On Phosphatidylserine As A Key Signaling Moiety During Adipocyte Differentiation, Brady Jeffrey Barron
A Thesis On Phosphatidylserine As A Key Signaling Moiety During Adipocyte Differentiation, Brady Jeffrey Barron
Arts & Sciences Graduate Student Theses and Dissertations
The adipose tissue is composed of specialized energy storage cells called adipocytes. In white adipose tissue, when committed precursor cells (preadipocytes), receive specific cues, the preadipocytes differentiate into mature adipocytes via an adipogenic gene program promoted by transcription factors such as PPAR. Phosphatidylserine (PS) is a phospholipid asymmetrically maintained on the inner leaflet of the plasma membrane in healthy cells. PS flipping to the outer leaflet is a well-known hallmark of cell death, such as apoptosis. Here, while exploring the interplay between PS exposure and adipose tissue homeostasis, we made a surprising discovery in that non apoptotic PS exposure occurs …
Water Beetles (Coleoptera) Associated With Afrotemperate Forest Patches In The Garden Route National Park, South Africa, Matthew S. Bird, David T. Bilton, Musa C. Mlambo, Renzo Perissinotto
Water Beetles (Coleoptera) Associated With Afrotemperate Forest Patches In The Garden Route National Park, South Africa, Matthew S. Bird, David T. Bilton, Musa C. Mlambo, Renzo Perissinotto
School of Biological and Marine Sciences
Southern Afrotemperate Forest is concentrated in the southern Cape region of South Africa and whilst it is relatively well known botanically, the fauna, specifically the aquatic invertebrate fauna, is poorly documented. The majority of remaining intact forest habitat is contained within the Garden Route National Park (GRNP), which straddles the provincial boundary between the Western and Eastern Cape. This study undertakes a survey of the water beetle fauna inhabiting the GRNP. The aquatic ecosystems within temperate forests of the region are poorly researched from an ecological and biodiversity perspective, despite being known to harbour endemic invertebrate elements. We collected water …
Vista: October 19, 2023, University Of San Diego
Vista: October 19, 2023, University Of San Diego
USD Vista (1965-)
No abstract provided.
Kenyon Collegian - October 19, 2023
The Urgent Need For Preparing Anti-Oppressive Citizens In Elementary Social Studies: A Conceptual And Pragmatic Framework For Educators, Erin Piedmont
The Urgent Need For Preparing Anti-Oppressive Citizens In Elementary Social Studies: A Conceptual And Pragmatic Framework For Educators, Erin Piedmont
Teaching Social Studies in the Peach State
No abstract provided.
Bioinspired Materials For Underwater Adhesion With Pathways To Switchability, Chanhong Lee, Huiqi Shi, Jiyoung Jung, Bowen Zheng, Kan Wang, Ravi Tutika, Rong Long, Bruce Lee, Grace X. Gu, Michael D. Bartlett
Bioinspired Materials For Underwater Adhesion With Pathways To Switchability, Chanhong Lee, Huiqi Shi, Jiyoung Jung, Bowen Zheng, Kan Wang, Ravi Tutika, Rong Long, Bruce Lee, Grace X. Gu, Michael D. Bartlett
Michigan Tech Publications
Strong adherence to underwater or wet surfaces for applications like tissue adhesion and underwater robotics is a significant challenge. This is especially apparent when switchable adhesion is required that demands rapid attachment, high adhesive capacity, and easy release. Nature displays a spectrum of permanent to reversible attachment from organisms ranging from the mussel to the octopus, providing inspiration for underwater adhesion design that has yet to be fully leveraged in synthetic systems. Here, we review the challenges and opportunities for creating underwater adhesives with a pathway to switchability. We discuss key material, geometric, modeling, and design tools necessary to achieve …
Mitochondrial Transplantation And Transfer: The Promising Method For Diseases, Gökhan Burçi̇n Kubat
Mitochondrial Transplantation And Transfer: The Promising Method For Diseases, Gökhan Burçi̇n Kubat
Turkish Journal of Biology
Mitochondria are organelles that serve as the powerhouses for cellular bioenergetics in eukaryotic cells. It is responsible for mitochondrial adenosine triphosphate (ATP) generation, cell signaling and activity, calcium balance, cell survival, proliferation, apoptosis, and autophagy. Mitochondrial transplantation is a promising disease therapy that involves the recovery of mitochondrial dysfunction using isolated functioning mitochondria. The objective of the present article is to provide current knowledge on natural mitochondrial transfer processes, in vitro and in vivo applications of mitochondrial transplantation, clinical trials, and challenges associated with mitochondrial transplantation.
Investigating The Roles Of Active Site Residues In Mycobacterium Tuberculosis Indole-3-Glycerol Phosphate Synthase, A Potential Target For Antitubercular Agents, David W. Konas, Sarah Cho, Oshane D. Thomas, Maryum M. Bhatti, Katherine Leon Hernandez, Cinthya Moran, Hedda Booter, Thomas Candela, Joseph Lacap, Paige Mcfadden, Savannah Van Den Berg, Alyssa M. Welter, Ashley Peralta, Cheryl A. Janson, Jaclyn Catalano, Nina M. Goodey
Investigating The Roles Of Active Site Residues In Mycobacterium Tuberculosis Indole-3-Glycerol Phosphate Synthase, A Potential Target For Antitubercular Agents, David W. Konas, Sarah Cho, Oshane D. Thomas, Maryum M. Bhatti, Katherine Leon Hernandez, Cinthya Moran, Hedda Booter, Thomas Candela, Joseph Lacap, Paige Mcfadden, Savannah Van Den Berg, Alyssa M. Welter, Ashley Peralta, Cheryl A. Janson, Jaclyn Catalano, Nina M. Goodey
Department of Chemistry and Biochemistry Faculty Scholarship and Creative Works
Mycobacterium tuberculosis drug resistance is emerging and new drug targets are needed. Tryptophan biosynthesis is necessary for M. tuberculosis replication and virulence. Indole-3-glycerol phosphate synthase (IGPS) catalyzes a step in M. tuberculosis tryptophan biosynthesis and has been suggested as a potential anti-infective target, but our understanding of this enzyme is limited. To aid in inhibitor design and gain a greater mechanistic picture of this enzyme, there is a need to understand the roles of active site amino acids in ligand binding and catalysis. In this work, we explored the roles of conserved active site amino acids Glu57, Lys59, Lys119, Glu168, …
Caracterización De Poblaciones De Especies Endémicas En Bosque Tropical Seco Semideciduo. Parque Nacional Machalilla, Manabí, Ecuador, Joselyn K. Castro, Jimmy J. Cevallos Zambrano, Francisco X. Pico Franco, Juan C. Palacios Peñafiel, Esteban Chirino Miranda
Caracterización De Poblaciones De Especies Endémicas En Bosque Tropical Seco Semideciduo. Parque Nacional Machalilla, Manabí, Ecuador, Joselyn K. Castro, Jimmy J. Cevallos Zambrano, Francisco X. Pico Franco, Juan C. Palacios Peñafiel, Esteban Chirino Miranda
Neotropical Biodiversity
No abstract provided.
Criminalization Of Environmental Harms In Bangladesh And The United States, Md Lokman Hussain
Criminalization Of Environmental Harms In Bangladesh And The United States, Md Lokman Hussain
Theses and Dissertations
This study explores and compares the nature, features, and measures of criminalization of environmental harms in Bangladesh and United States. The exploration is based on the descriptive and analytical comparison of the legal frameworks addressing the environmental harms in these two countries. To explore how are environmental harms criminalized in Bangladesh and United States, following aspects were described and compared: the criminalizing power of the state, criminalization of environmental harms regarding air pollution, water pollution, protection of biodiversity, waste management, and use of pesticide, theoretical frameworks in explaining criminalization, role of constitution and international law.
Polar Oceans And Sea Ice In A Changing Climate, Megan D. Willis, Delphine Lannuzel, Brent Else, Hélène Angot, Karley Campbell, Odile Crabeck, Bruno Delille, Hakase Hayashida, Martine Lizotte, Brice Loose, Klaus M. Meiners, Lisa Miller, Sebastien Moreau, Daiki Nomura, John Prytherch, Julia Schmale, Nadja Steiner, Letizia Tedesco, Jennie Thomas
Polar Oceans And Sea Ice In A Changing Climate, Megan D. Willis, Delphine Lannuzel, Brent Else, Hélène Angot, Karley Campbell, Odile Crabeck, Bruno Delille, Hakase Hayashida, Martine Lizotte, Brice Loose, Klaus M. Meiners, Lisa Miller, Sebastien Moreau, Daiki Nomura, John Prytherch, Julia Schmale, Nadja Steiner, Letizia Tedesco, Jennie Thomas
Graduate School of Oceanography Faculty Publications
Polar oceans and sea ice cover 15% of the Earth’s ocean surface, and the environment is changing rapidly at both poles. Improving knowledge on the interactions between the atmospheric and oceanic realms in the polar regions, a Surface Ocean-Lower Atmosphere Study (SOLAS) project key focus, is essential to understanding the Earth system in the context of climate change. However, our ability to monitor the pace and magnitude of changes in the polar regions and evaluate their impacts for the rest of the globe is limited by both remoteness and sea-ice coverage. Sea ice not only supports biological activity and mediates …
The Lumberjack, October 18, 2023
The Lumberjack, October 18, 2023
Cal Poly Humboldt's Student Newspaper
The student newspaper of Humboldt State University.
Androgen Receptor Contributes To Repairing Dna Damage Induced By Inflammation And Oxidative Stress In Prostate Cancer, Bi̇lge Debeleç Bütüner, Nurşah Ertunç Hasbal, Eli̇f İşel, Dirk Roggenbuck, Kemal Sami̇ Korkmaz
Androgen Receptor Contributes To Repairing Dna Damage Induced By Inflammation And Oxidative Stress In Prostate Cancer, Bi̇lge Debeleç Bütüner, Nurşah Ertunç Hasbal, Eli̇f İşel, Dirk Roggenbuck, Kemal Sami̇ Korkmaz
Turkish Journal of Biology
Background: Androgen deprivation therapy remains the first-line therapy option for prostate cancer, mostly resulting in the transition of the disease to a castration-resistant state. The lack of androgen signaling during therapy affects various cellular processes, which sometimes paradoxically contributes to cancer progression. As androgen receptor (AR) signaling is known to contribute to oxidative stress regulation, loss of AR may also affect DNA damage level and the response mechanism in oxidant and inflammatory conditions of the prostate tumor microenvironment. Therefore, this study aimed to investigate the role of AR and AR-regulated tumor suppressor NKX3.1 upon oxidative stress-induced DNA damage response (DDR) …
Improving Human-Automation Collaboration In Motion Planning, Torin J. Adamson
Improving Human-Automation Collaboration In Motion Planning, Torin J. Adamson
Computer Science ETDs
Human-automation collaboration is becoming a part of everyday life as AI helps us drive, make decisions, and solve a variety of other tasks. However, safe and effective collaboration systems depend on factors in trust, communication, and more. Existing studies to explore these are typically carried out in laboratory settings, providing robust data under tight environmental control. However, human behavior evolves over time, driven by external factors that cannot be fully captured in single participation sessions. These factors form the "human context", contextualizing the behavioral data for a more complete understanding. In this thesis, video game adaptations upon conventional subject studies …
Advances And Challenges In Bioinformatics And Biomedical Engineering: Iwbbio 2020, Olga Valenzuela, Mario Cannataro, Irena Rusur, Jianxin Wang, Zhongming Zhao, Ignacio Rojas
Advances And Challenges In Bioinformatics And Biomedical Engineering: Iwbbio 2020, Olga Valenzuela, Mario Cannataro, Irena Rusur, Jianxin Wang, Zhongming Zhao, Ignacio Rojas
Faculty, Staff and Student Publications
This Supplement issue, presents five research articles which are distributed, mainly due to the subject they address, from the 8th International Work-Conference on Bioinformatics and Biomedical Engineering (IWBBIO 2020), which was held on line, during September, 30th-2nd October, 2020. These contributions have been chosen because of their quality and the importance of their findings. Those contributions were then invited to participate in this supplement for the following journals of BMC: BMC Bioinformatics and BMC Genomics. In the present Editorial in BMC journal, we summarize the contributions that provide a clear overview of the thematic areas covered by the IWBBIO conference, …