Digital Commons Network^™

Relationship Between Bats And Prairie-Dog (Cynomys Ludovicianus) Colonies In Western Kansas, Mario N. Rodriguez

Master's Theses or Doctor of Nursing Practice

Although it is known that prairie dog colonies can increase biodiversity in the areas surrounding them, there is extraordinarily little known about the relationship between bats and black-tailed prairie dogs (Cynomys ludovicianus). In a recent study from the Front Range of Colorado, several bat species were found to be consistently flying around prairie dog colonies, presumably foraging due to increased insect diversity and abundance. Despite the importance of prairie dogs to the ecosystem, prairie dog colonies are usually eradicated due to the perception that they adversely impact cattle grazing. If insectivorous bats are attracted to prairie dog colonies …

Methylation Patterns Across Tissue Type And Time In Peromyscus Leucopus: A Targeted Museum Study, Loryn Smith

Master's Theses or Doctor of Nursing Practice

Museum specimens are a vital data source for many types of studies. One relatively new use includes studying methylation patterns. Methylation patterns are a form of epigenetics or how gene expression changes without alteration of the genetic code. These patterns have been examined in many mammals. However, the focus has previously been on overall epigenetic patterns. Few studies have investigated whether methylation patterns differ across tissue types, time, or preservation method. In this study, I compared methylation patterns in muscle, liver, toe pads, and nasal bones from Peromyscus leucopus (white-footed mouse) museum specimens collected in 2022, 2018, 2014, and 2008 …

Conservation Status Of The Chihuahuan Green Toad, Anaxyrus Debilis, In Western Kansas Range, Mackenzie Reh

Master's Theses or Doctor of Nursing Practice

Amphibians remain an important model organism closely associated with environmental conditions and ecological processes. They are considered critical bioindicators of the relative health of ecosystems providing insights into levels of pollution, such as agricultural and industrial runoff, effects of UVB increases, ecosystem service functionality and much more (Rohman et al. 2021). Amphibians are an essential food source to organisms at higher trophic levels and to humans in developing countries (Schleich et al. 1996). Amphibians also provide pest control for agricultural and urban landscapes (Warkentin et al. 2009). Amphibians provide novel medicinal treatments for a wide variety of human ailments and …

Equity And Equality In Learning In Asia-Pacific: What Do Results From Large-Scale Assessments Tell Us? Gender In Focus Policy Brief, Syeda Kashfee Ahmed, Anna Dabrowski, Jacqueline Cheng, Victoria Klimova, Isabella Mccallum

Global education monitoring

This policy brief investigates gender disparities in learning outcomes and the factors contributing to these disparities as identified in large-scale assessment data in Southeast Asia. It additionally provides a set of recommendations aimed at enhancing equitable student learning outcomes while advocating for comprehensive support of gender-based interventions within educational quality initiatives, spanning both systemic and school-level support. The findings presented in this brief are drawn from large-scale assessment (LSA) datasets and secondary analysis of these sources. For more detailed information regarding the large-scale assessments in Southeast Asia, please refer to the appendix section.

Understanding The Value Of Friendships: Exploring The Different Characteristics Of Virtual World Friendships Compared To Real World Friendships, Samantha Baires

Master's Theses or Doctor of Nursing Practice

Research on video games, social media, and computer games has focused on specific social characteristics such as violence, communication, and social isolation. Most aspects of virtual world gaming and online relationships are considered inferior, if not damaging, to those who spend time on these platforms. Virtual relationships are often considered secondary to traditional relationships. Such relationships are seen as replacements for traditional friendships, leading to research focusing on replacement rather than value. Little research focuses on how a virtual world friendship compares to a traditional friendship and the value it may serve to individuals in the relationship. The present study …

Grassland Nesting Birds And Visual Obstruction Measurements In Western Kansas On Smoky Valley Ranch, Connor J. Champney

Master's Theses or Doctor of Nursing Practice

North American grassland declines and increasing changes in land use patterns have revived the importance of studying grasslands and their inhabitants. Grassland breeding bird populations are declining rapidly, and conservation efforts are ramping up. Smoky Valley Ranch (SVR) owned by The Nature Conservancy (TNC) is in Logan County, Kansas. Surrounding private land is characteristically comprised of row crops, livestock agriculture, Conservation Reserve Program (CRP), and a few patches of native and restored prairie. The study of obligate grassland birds utilizing this area during the breeding season is essential to the proliferation of grassland bird nesting habitat in western, Kansas. The …

The Transformation Of Cherokee Medicial Practices And The Hesitations That Surround Them, Rebecca Bills

Theses

Studies on traditional Cherokee medicine during the 1800s explained Cherokee religious beliefs and the treatments they used to heal the members of their community. However, no updated research has been done to see if Cherokees are still using traditional medicine and if they are, which kinds are they using in the 21st century. This is in part due to the fact that Native Americans and the U.S. government have a complicated relationship from centuries of mistreatment, broken treaties, and the removal from their ancestral homelands. This has created a distrust between native and non-natives. Today, traditional healers' identities are protected …

Habitat Associations And Fine-Scale Movements Of The Red-Spotted Toad (Anaxyrus Punctatus) In Kansas And The Efficacy Of Remote Telemetry For Monitoring Small-Scale Movements, Elisabeth Russell

Master's Theses or Doctor of Nursing Practice

As climate change progresses, arid-adapted anurans might be particularly susceptible to population declines because of their reliance on ephemeral pools for successful reproduction. Because arid-adapted anurans are difficult to study due to short active seasons and cryptic lifestyles, little is known about their habitat preferences. One such arid-adapted species is the Red-Spotted Toad (Anaxyrus punctatus; RST), a Kansas Species in Need of Conservation. Since this designation in 1987, little research has been conducted to understand their conservation needs. During the summers of 2021 and 2022, RST surveys were conducted both near areas where the species has historically been …

Timing Of Diversification, Dispersal, And Biogeography Of Parrots In The Genus Amazona (Psittaciformes: Psittacidae) Throughout The Caribbean, Visualized In Gis, Christopher Kingwill

Master's Theses or Doctor of Nursing Practice

Avian fossil records from across the Caribbean (Greater and Lesser Antilles) demonstrate higher avian diversity prior to extinction events due to climate change at the end of the Pleistocene and human impact across the Caribbean throughout the Holocene. Amazon parrots (Amazona) are a diverse genus of New World parrots found throughout Central and South America, as well as the Caribbean. Their phylogeny and evolutionary history, specifically for Caribbean species, has been debated in terms of source areas in Central and South America and the timing of and number of colonization events to different islands that preceded diversification into …

The Relationship Between Climate Social Vulnerability And Asthma, Diane Nunez

Master's Theses or Doctor of Nursing Practice

Asthma is a chronic respiratory disease that affects millions of people worldwide, the incidence and severity of asthma is influenced influenced by various factors, including air masses, and weather conditions. Asthma can also disproportionately affect different sociodemographics groups, leading to inequalities and injustices. This study used statistical analysis and GIS to analyze the spatial distribution of asthma calls and their relationship to sociodemographic traits in Wichita, KS, Tulsa, OK, and Oklahoma City, OK, and the seasonal distribution of asthma calls and their relationship to air masses. Results show that the relationship between asthma prevalence is higher among certain sociodemographic groups, …

The Impact Of Study Strategies On Academic Performance For Medical Students At Wright State University, Markia Black

Browse all Theses and Dissertations

Studying plays an important role in the academic success of medical students. It is likely that ineffective study skills result in poor performances on required standardized exams. There is a concern for the lack of empirical data related to what study strategies are the most productive for medical students to practice. My goal is to 1) identify what study strategies students use in their pre-clinical years of medical school, 2) determine if these strategies impact students’ performance on Comprehensive Basic Science Exams and Step 1 exam, and 3) identify study methods that best support student achievement in the pre-clinical phase …

Brain Morphometry From Neuroimaging As A Biomarker For Alzheimer's Disease, Nonyelum Benedicta Aniebo

Browse all Theses and Dissertations

Alzheimer’s disease (AD) is the seventh leading cause of death globally with an estimated 6.5 million Americans aged 65 and above living with Alzheimer’s dementia in 2022 and at a projected national cost of $321 billion. AD is characterized by a progressive and irreversible neurodegenerative dysfunction with clinical symptoms such as deterioration in cognition and memory loss. The Alzheimer’s Disease Neuroimaging Initiative (ADNI) is a multi-site, public-private global research initiative that supports both investigation and development of treatments that slow or terminate AD progression. The study included 60 participants, comprising 30 AD and 30 control cohorts respectively. All participants were …

Teaching Physics While Female : A Phenomenological Study Of Female High School Physics Teachers, Hope Strickland

Browse all Theses and Dissertations

The lived experiences of female high school physics teachers were researched in this study with the aim of gaining a better understanding of their decisions to remain in the classroom or to leave the teaching profession. To allow the participants to describe their background and teaching experiences, as well as the meaning they found in them, a transcendental phenomenological approach was used during this research. To create a richer representation of the phenomenon, fourteen women ranging from 0-31 years of experience teaching high school physics were interviewed for this study. The data from the interviews was analyzed through the lens …

Accelerating Precision Station Keeping For Automated Aircraft, James D. Anderson

Browse all Theses and Dissertations

Automated vehicles pose challenges in various research domains, including robotics, machine learning, computer vision, public safety, system certification, and beyond. These vehicles autonomously handle navigation and locomotion, often requiring minimal user interaction, and can operate on land, in water, or in the air. In the context of aircraft, one specific application is Automated Aerial Refueling (AAR). Traditional aerial refueling involves a "tanker" aircraft using a mechanism, such as a rigid boom arm or a flexible hose, to transfer fuel to another aircraft designated as the "receiver". For AAR, the boom arm may be maneuvered automatically, or in certain instances the …

Investigating The Mechanism Of Tdp-43 Toxicity In Yeast: A Model For Amyotrophic Lateral Sclerosis, Cassidy Nicole Alspaugh

Browse all Theses and Dissertations

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease that causes the degeneration of motor neurons which leads to loss of motor function and eventual death. Over 20 genes have been implicated in ALS’s pathogenesis, one being TARDBP, which codes for TDP-43. TDP-43 mislocalizes from the nucleus, accumulates, and then aggregates in the cytoplasm and is linked to cellular toxicity. We have modeled this aggregation and toxicity of TDP-43 in budding yeast. From genetic screens of human genes and their ability to modulate TDP-43 toxicity, we found 50 human genes that were able to reduce TDP-43 toxicity. 12 of these …

To Determine The Role Of The Platelet Activating Factor - Receptor In Folfirinox Therapy-Mediated Microvesicles Particle Generation, Krishna Awasthi

Browse all Theses and Dissertations

Given that Pancreatic cancer continues to be one of the primary causes of cancer-related death and that existing treatment options have a poor success rate, it is important to investigate the role of potential factor(s) involved in pancreatic cancer growth or diminishing the effectiveness of chemotherapeutic agents. An alternative regimen for pancreatic cancer treatment called FOLFIRINOX has shown to increase the survival rate and improve Eastern Cooperative Oncology Group (ECOG) performance status score among the pancreatic cancer patients. However, FOLFIRINOX therapy is associated with several side effects. Through mechanisms involving the secretion of microvesicle particles (MVP), studies, including ours have …

Synthesis Of Derivatives Of Hexafluoroisopropanol, Meshal Alghamdi

Electronic Theses and Dissertations

Fluorinated organic molecules have significant potential in medicinal chemistry and drug discovery. Consequently, 20–25% of the FDA approved drugs contain at least one fluorine atom. Functional groups displaying high levels of fluorination are attracting new interest to expand the chemical space for drug development. A hexafluoroisopropanol (HFIP) group is one of these groups which combines high levels of fluorination with an adjacent alcohol. This functionality displays a unique hydrogen bond donor without any nucleophilicity. Recent studies have shown that the HFIP can be employed as a building block for the synthesis of drug-like molecules, and its incorporation into small molecules …

The Double Descent Behavior In A Two Layer Neural Network For Binary Classification, Chathurika Srimali Abeykoon

Electronic Theses and Dissertations

Machine learning and artificial intelligence have changed the world significantly in recent years. Its breakthrough innovations take machine learning to a whole new level where machines can learn to recognize tasks, inspired by the human brain's neural networks. The generally accepted belief about training these machines or models is that \larger models and more data are always better". In classical statistics, the test error is a \U-shaped" curve where the bigger and more complex models have higher test errors which is not favorable. But recent studies observed a surprising concept about test error called the double descent phenomenon where the …

Can Graphene-Coated Sand Enhance Water Reuse By Improving Water Quality In The Presence Of Municipal Treated Wastewater?, Madelyn Barber

Electronic Theses and Dissertations

The need for alternative water sources is dramatically increasing. Therefore, it is essential to develop alternative water sources to meet the current water scarcity challenges. Water reclamation, recycling, and reuse involving treated municipal and or animal wastewater address these challenges by resolving water resource issues and creating new sources of high-quality water supplies. However, the presence of bacteria, high levels of nutrients, and turbidity, as well as the occurrence of chemicals of emerging concern (CECs) in the treated wastewater, combined with the willingness of the public to use treated wastewater can undermine the wide application of water reuse. Implementing affordable …

Neverender, David James Gambino

Electronic Theses and Dissertations

This is a work of fiction exploring the Global War on Terror from the perspective of US aircrew servicemembers.

Development And Characterization Of Cannabidiol And Rho Kinase Inhibitor Combination Formulations For Ophthalmic Use, Mihir Sanjay Ghonge

Electronic Theses and Dissertations

Glaucoma, the leading cause of irreversible blindness globally, is a neurodegenerative disease marked by progressive death of the retinal ganglion cells in the eye. In 2018, FDA approved a 0.02% ophthalmic solution of netarsudil mesylate (NM), Rhopressa®, a rho kinase inhibitor, for the reduction of intraocular pressure in patients with glaucoma or ocular hypertension; the first new drug class in more than two decades. Cannabidiol (CBD) has been studied for its effects on intraocular pressure since the 1980s. In 2022, a study established that topical administration of CBD (1% w/v) decreased the intraocular pressure in pigmented Dutch Belted Rabbits. This …

Development And Validation Of Different Analytical Techniques For The Quantification Of Cannabinoids And Cannflavins In Cannabis And Cannabis-Based Products, Mostafa Elhendawy

Electronic Theses and Dissertations

The main objective of this study is to modify, develop, and validate techniques for detecting and quantifying the levels of major and minor cannabinoids, along with their corresponding acids, in Cannabis sativa plants and certain marketed products. To achieve this goal, the research employs Gas Chromatography (GC), High-Performance Liquid Chromatography (HPLC), and a novel spectroscopic method known as Absorbance-Transmittance Excitation Emission Matrix Spectroscopy (A-TEEM). Another study validated and applied the HPLC technique to analyze the unique class of flavonoids (Cannflavins) found in various parts of the cannabis plant, including leaves, buds, and pollen.

The A-TEEM method was developed and validated …

Formulation And Characterization Of Oral Thin Films (Otfs) Of 17-Beta Estradiol, Srijan Kaur Hora

Electronic Theses and Dissertations

Estrogen Hormonal Replacement Therapy is the most common and most effective means for post-menopausal women to get relief from vasomotor symptoms. Oral films are feasible approaches to designing a dosage form that can include the benefits of oral delivery but circumvent the side effects and risks associated with first-pass metabolism and transdermal delivery. The film releases the drug when it comes in contact with water leaving behind a gel.

In this study, different grades of Hydroxy propyl cellulose (HPC-M, HPC-SL, HPC-SSL) were used as film-forming polymers; propylene glycol was used as a plasticizer, Citric Acid as saliva stimulating agent, Mannitol …

Development Of Gastroretentive Floating Pellets Using Hot Melt Extrusion, Mengwen Li

Electronic Theses and Dissertations

This work aimed to develop a novel gastroretentive floating drug delivery system based on non-effervescent technology using hot melt extrusion technology to synergize gastric floating and bioadhesion strategies to achieve extended drug release. All components of the formulations including the active pharmaceutical ingredient (API) of the drug (theophylline), the polymers acting as a floating matrix and achieving the adhesive function (chitosan, HPC HF, HPMC K4M, and PEO N80), and the gas generating agent sodium bicarbonate were directly fed into the hot melt extruder to prepare the novel gastroretentive pellets. The uniformity of all formulations met the United States Pharmacopeia criteria. …

Teachers' Experiences Implementing The 2018 Mississippi College And Career Readiness Standards For Science, Lydia Lytal

Electronic Theses and Dissertations

Teachers have had to use standards to teach with since the 1980’s. The CCRS has made a significant shift in how standards are written and the expectations of students in learning them. With the three-dimensional design, teachers are required to change their pedagogy in order to implement the standards with fidelity. That requires training, support, and resources for the teachers. The purpose of this study was to provide insight in the experiences of high school teachers in Mississippi as they implemented the standards. Additionally, the researcher revealed emotions related to implementation and differences related to teachers in a tested subject …

Reimagining The Radical: Gender, Genre, And Anti-Fascism In Women's Writing At Mid-Century, Allison Nick

Electronic Theses and Dissertations

This dissertation looks at the work of four women writers—Martha Gellhorn, Elizabeth Bowen, Pearl S. Buck, and Rebecca West—who are united in their transnational commitment to critiquing the global rise of fascism and the fraught democratic imperatives of their own countries. “Reimagining the Radical” focuses on the temporal gap between modernism and postmodernism and is inspired by work from scholars like Marina MacKay, Lyndsey Stonebridge, and Beryl Pong to claim and define mid-century literature. By rethinking the bounds of modernism, “Reimagining the Radical” also seeks to fill the gaps in feminist history—between the suffragism of the early 20th century and …

The World Wide Web Of Women: A Case In Favor Of Global Feminist Coalitions In The Information Age, Hannah S. Phillips

Electronic Theses and Dissertations

The aim of this thesis is to argue that online feminist coalitions can be both locally specific and globally accessible. Postcolonial feminist theorist Chandra Talpade Mohanty in her 1984 article “Under Western Eyes: Feminist Scholarship and Colonial Discourses,” argues that there is no real evidence to classify all women as a “Woman” because cultural differences and imbalances of power create a myriad of experiences that cannot be homogenized. However, Mohanty is not arguing that women do not have individual experiences with gender injustice. On the contrary, all women have experiences with gender injustice; these experiences are simply all not the …

Hiv-1 Tat And Neuroendocrine Aging: Potential Benefits Of Neurosteroid-Based Therapy To Attenuate Premature Age-Related Comorbidities In The Era Of Antiretroviral Therapy, Alaa Nader Qrareya

Electronic Theses and Dissertations

The primary objectives of this dissertation are to assess the interaction between human immunodeficiency virus type-1 (HIV-1) trans-activator of transcription (Tat) protein and neuroendocrine status on the pathology of Tat/age-related comorbidities and to investigate the potential benefit of hormonal therapy in attenuating Tat/age insults. The advent of combined antiretroviral therapy (cART) has increased longevity among people living with HIV (PLWH). However, cART cannot fully eradicate viral reservoirs within the central nervous system (CNS). Therefore, ~50-60% of virally-suppressed PLWH experience neurological and psychological sequelae called “neuroHIV”. Moreover, PLWH are more vulnerable to developing premature age-related comorbidities. In PLWH, hypogonadism is common …

Detection Of Rayleigh Faded Signal Using Two Distributed Sensors, Sayantan Saha

Electronic Theses and Dissertations

Distributed detection(DD) is an area of interest in the Cognitive Radio(CR) Network domain. With the help of geographically dispersed sensors and a Fusion Center(FC) (i.e. the network element which generates the global network decision), a DD system can determine the presence or absence of a primary user signal. This prevents any harmful interference by a secondary user who is trying to gain access to the unoccupied spectrum opportunistically. DD system gained its popularity in spectrum analysis due to the limited bandwidth of the reporting channels between the sensors and their fusion center.

Buscando Perdón: Validation And Considerations For A Spanish Translation Of The Forgiveness Reconciliation Inventory, Mario David Sobrino

Electronic Theses and Dissertations

With influences from both cultural norms and commonly held spiritual beliefs, members of the Latinx population are vulnerable to enabling unhealthy interpersonal relationships that primarily benefit others while potentially harming their own wellness. A Spanish translation (called the Inventario del Perdón y Reconciliación [IPR]) for the Forgiveness and Reconciliation Inventory (FRI) was created to identify its validity and reliability as a potential clinical resource for Spanish speaking mental health counseling clients dealing with the emotional difficulties of forgiveness and unjust cultural expectations within their relationships. Factor analysis on the IPR reported comparable yet slightly reduced psychometric properties to the FRI. …