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2023

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Gouverneur Morris And The Drafting Of The Federalist Constitution, William M. Treanor Jan 2023

Gouverneur Morris And The Drafting Of The Federalist Constitution, William M. Treanor

Georgetown Law Faculty Publications and Other Works

The Salmon P. Chase Colloquium series has had two themes: One is great moments in constitutional law, and the other is people who have been forgotten but should not have been. This colloquium is primarily in the latter category—it is about a forgotten founder of the Constitution. But the Constitution has more than one forgotten founder. I did a Google search this afternoon for “Forgotten Founder” and there are a whole series of books on various people who are the Constitution’s Forgotten Founder. So the Chase Colloquium series has another decade of subjects: Luther Martin, George Mason, Charles Pinckney, Roger …


Disrupting Data Cartels By Editing Wikipedia, Eun Hee Han, Amanda Levendowski, Jonah Perlin Jan 2023

Disrupting Data Cartels By Editing Wikipedia, Eun Hee Han, Amanda Levendowski, Jonah Perlin

Georgetown Law Faculty Publications and Other Works

Legal discourse in the digital public square is driven by memoranda, motions, briefs, contracts, legislation, testimony, and judicial opinions. And as lawyers are taught from their first day of law school, the strength of these genres of legal communication is built on authority. But finding that authority often depends on a duopoly of for-profit legal research resources: Westlaw and Lexis. Although contemporary legal practice relies on these databases, they are far from ethically neutral. Not only are these “data cartels” expensive-- creating significant access to justice challenges--they also are controlled by parent companies that profit by providing information to Immigration …


Beyond The Business Case: Moving From Transactional To Transformational Inclusion, Jamillah Bowman Williams Jan 2023

Beyond The Business Case: Moving From Transactional To Transformational Inclusion, Jamillah Bowman Williams

Georgetown Law Faculty Publications and Other Works

While workplace diversity is a hot topic, the extent to which the diversity management movement has effectively improved intergroup relations and reduced racial inequality remains unclear. Despite large investments in diversity and inclusion training and other company wide initiatives, historically excluded groups remain vastly underrepresented in leadership and the most lucrative careers, such as finance, law, and technology. This calls the efficacy of diversity, equity, and inclusion (DEI) efforts into question, particularly with respect to reducing racial inequality in the workplace.

This Article explains why it is time for organizational leaders to move beyond the transactional case for diversity and …


Race And Entrepreneurship: Reclaiming Narratives, Priya Baskaran, Alicia E. Plerhoples Jan 2023

Race And Entrepreneurship: Reclaiming Narratives, Priya Baskaran, Alicia E. Plerhoples

Georgetown Law Faculty Publications and Other Works

This essay makes the case for engaging in counter-narratives and inclusive storytelling within the transactional clinic curriculum. The authors leverage lessons from Critical Race Theory to amplify the voices and experiences of underrepresented entrepreneurs and marginalized communities in both clinic seminar and selected casework. In doing so, we challenge hegemonic narratives of entrepreneurship and expose our law students to the presence and impact of interlocking systems of subordination that minimize the existence and contributions of entrepreneurs of color. We challenge our law students and ourselves to become more creative and thoughtful lawyers to a more inclusive and diverse set of …


Abila Keynote Address: Beyond International Law? A Dangerous Time, Gregory Shaffer Jan 2023

Abila Keynote Address: Beyond International Law? A Dangerous Time, Gregory Shaffer

Georgetown Law Faculty Publications and Other Works

In this keynote address for the 2023 International Law Weekend conference of the American Branch of the International Law Association (ABILA), I first address the dangers of the conference theme “beyond international law” at a time when challenges to international law and institutions increase and aim to constrain international law’s normative force. We have been here before. The world today recalls that of the interwar period, a time of growing economic insecurity and inequality that helped to catalyze the rise of authoritarian movements. During that period, Carl Schmitt was a leading legal theorist who eventually became a member of the …


Judges For Sale: The Effect Of Campaign Contributions On State Criminal Courts, Arturo Romero Yáñez, Neel U. Sukhatme Jan 2023

Judges For Sale: The Effect Of Campaign Contributions On State Criminal Courts, Arturo Romero Yáñez, Neel U. Sukhatme

Georgetown Law Faculty Publications and Other Works

Do campaign contributions impact democratic processes? Using donation data from Texas, we show that criminal defense attorneys who contribute to a district judge’s electoral campaign are preferentially assigned by that judge to indigent defense cases, i.e., public contracts in which the state pays private attorneys to represent poor defendants.

We estimate that attorney donors receive twice as many cases as non-donors during the month of their campaign contribution. Nearly two-thirds of this increase is explained by the contribution itself, with the remainder attributable to shared preferences within attorney-judge pairs, such as those based on professional, ideological, political, or personal ties. …


Aspiration Thrombectomy Versus Stent Retriever Thrombectomy Alone For Acute Ischemic Stroke: Evaluating The Overlapping Meta-Analyses, Ahmed Y. Azzam, Sherief Ghozy, Kevin M. Kallmes, Gautam Adusumilli, Jeremy J. Heit, Ameer E. Hassan, Ramanathan Kadirvel, David F. Kallmes Jan 2023

Aspiration Thrombectomy Versus Stent Retriever Thrombectomy Alone For Acute Ischemic Stroke: Evaluating The Overlapping Meta-Analyses, Ahmed Y. Azzam, Sherief Ghozy, Kevin M. Kallmes, Gautam Adusumilli, Jeremy J. Heit, Ameer E. Hassan, Ramanathan Kadirvel, David F. Kallmes

School of Medicine Publications

Background Previous studies comparing a direct aspiration first pass technique (ADAPT) and stent retrievers have inconsistent methodologies and data reporting, limiting the ability to accurately assimilate data from different studies that would inform treatment of acute ischemic stroke (AIS) treatment.

Objective To conduct a systematic review to discuss and compare the findings of all relevant meta-analysis studies comparing the efficacy of the ADAPT and stent retriever techniques.

Methods The study was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA), where meta-analyses comparing the efficacy of the ADAPT technique and stent retrievers in the treatment of …


Multiple Sclerosis Followed By Neuromyelitis Optica Spectrum Disorder: From The National Multiple Sclerosis Society Case Conference Proceedings, Carolyn Goldschmidt, Steven L. Galetta, Robert P. Lisak, Laura J. Balcer, Andrew Hellman, Michael K. Racke, Amy E. Lovett-Racke, Roberto A. Cruz Jan 2023

Multiple Sclerosis Followed By Neuromyelitis Optica Spectrum Disorder: From The National Multiple Sclerosis Society Case Conference Proceedings, Carolyn Goldschmidt, Steven L. Galetta, Robert P. Lisak, Laura J. Balcer, Andrew Hellman, Michael K. Racke, Amy E. Lovett-Racke, Roberto A. Cruz

School of Medicine Publications

A woman presented at age 18 years with partial myelitis and diplopia and experienced multiple subsequent relapses. Her MRI demonstrated T2 abnormalities characteristic of multiple sclerosis (MS) (white matter ovoid lesions and Dawson fingers), and CSF demonstrated an elevated IgG index and oligoclonal bands restricted to the CSF. Diagnosed with clinically definite relapsing-remitting MS, she was treated with various MS disease-modifying therapies and eventually began experiencing secondary progression. At age 57 years, she developed an acute longitudinally extensive transverse myelitis and was found to have AQP4 antibodies by cell-based assay. Our analysis of the clinical course, radiographic findings, molecular diagnostic …


Learning A Healthy Rhythm: An Intervention To Increase Children’S Resources For Stress Management, Kristin Haglund, Amanda L. King, Abir K. Bekhet, Mauricio Garnier-Villarreal, Karen Olson, Rashs Atshan, Angela Ortiz, Johanna De Los Santos, Ruth Ann Belknap Jan 2023

Learning A Healthy Rhythm: An Intervention To Increase Children’S Resources For Stress Management, Kristin Haglund, Amanda L. King, Abir K. Bekhet, Mauricio Garnier-Villarreal, Karen Olson, Rashs Atshan, Angela Ortiz, Johanna De Los Santos, Ruth Ann Belknap

College of Nursing Faculty Research and Publications

This article describes a pilot test of a community engaged, culturally relevant, arts-based intervention. The purpose was to increase children’s personal protective buffering resources. Protective buffering resources help children cope with stressful stimuli, reduce activation of their systemic stress response, mitigate allostatic load, and promote optimal health. The “Learning a Healthy Rhythm” intervention included a stress management component and an ongoing Afro-Latino percussion program for 18 children ages 9–11. The stress management component included educational content about stress, self-assessment of stress symptoms, and stress management techniques. A mixed-method intervention evaluation design was used. Qualitative data, quantitative data, and biometrics including …


A Single-Molecule Method For Measuring Fluorophore Labeling Yields For The Study Of Membrane Protein Oligomerization In Membranes, Melanie Ernst, Tugba N. Ozturk, Janice L. Robertson Jan 2023

A Single-Molecule Method For Measuring Fluorophore Labeling Yields For The Study Of Membrane Protein Oligomerization In Membranes, Melanie Ernst, Tugba N. Ozturk, Janice L. Robertson

2020-Current year OA Pubs

Membrane proteins are often observed as higher-order oligomers, and in some cases in multiple stoichiometric forms, raising the question of whether dynamic oligomerization can be linked to modulation of function. To better understand this potential regulatory mechanism, there is an ongoing effort to quantify equilibrium reactions of membrane protein oligomerization directly in membranes. Single-molecule photobleaching analysis is particularly useful for this as it provides a binary readout of fluorophores attached to protein subunits at dilute conditions. However, any quantification of stoichiometry also critically requires knowing the probability that a subunit is fluorescently labeled. Since labeling uncertainty is often unavoidable, we …


Sinonasal Outcomes Using Oral Corticosteroids In Patients With Chronic Rhinosinusitis With Nasal Polyps And Positive Sinonasal Cultures, Jhon F. Martinez Paredes, Angela M. Donaldson, Michael Marino, Garret Choby, Osarenoma Olomu, Razan Alfakir, Janalee K. Stokken, Erin O'Brien, Devyani Lal Jan 2023

Sinonasal Outcomes Using Oral Corticosteroids In Patients With Chronic Rhinosinusitis With Nasal Polyps And Positive Sinonasal Cultures, Jhon F. Martinez Paredes, Angela M. Donaldson, Michael Marino, Garret Choby, Osarenoma Olomu, Razan Alfakir, Janalee K. Stokken, Erin O'Brien, Devyani Lal

School of Medicine Publications

Introduction: Patients with chronic rhinosinusitis with nasal polyps (CRSwNP) and positive sinonasal bacterial cultures may be recalcitrant to topical therapy alone due to the additional local inflammatory burden associated with bacterial infection/colonization.

Objective: To evaluate sinonasal outcomes in CRSwNP patients with a positive perioperative bacterial culture, who were treated with postoperative intranasal corticosteroids (INCS) alone versus INCS in combination with a short-term course of oral corticosteroids (OCS).

Methods: This is a retrospective chart review of CRSwNP patients. A total of 59 patients met inclusion criteria, including positive perioperative bacterial culture and treatment with INCS with or without concomitant use of …


A Swimming Program For Children With Autism Spectrum Disorders: Assessing Critical Parameters From Caregivers’ Perspectives, Abir K. Bekhet, Norah L. Johnson, Tana Karenke, Amy V. Van Hecke Jan 2023

A Swimming Program For Children With Autism Spectrum Disorders: Assessing Critical Parameters From Caregivers’ Perspectives, Abir K. Bekhet, Norah L. Johnson, Tana Karenke, Amy V. Van Hecke

College of Nursing Faculty Research and Publications

One in 54 individuals is diagnosed with autism spectrum disorders (ASD). Swimming can impact the physical and mental well-being of persons with ASD, which in turn may improve their caregivers’ well-being. The purpose of this qualitative evaluation study is to assess the necessity, acceptability, feasibility, fidelity, and beginning effectiveness of a 12-session swimming training program (STP) at an indoor university pool designed to teach persons with ASD how to swim, and to teach caregivers precautions for safety around water. Participants included 7 boys, and 3 girls with ASD [mean age 7.05 years (SD 1.17)] and their caregivers. Results indicated that …


Physical Activity, Inflammation, And Physical Function In Older Adults: Results From The Health & Retirement Study, Jeanne L. Hlebichuk, Randall J. Gretebeck, Mauricio Garnier-Villarreal, Linda B. Piacentine, Maharaj Singh, Kimberlee A. Gretebeck Jan 2023

Physical Activity, Inflammation, And Physical Function In Older Adults: Results From The Health & Retirement Study, Jeanne L. Hlebichuk, Randall J. Gretebeck, Mauricio Garnier-Villarreal, Linda B. Piacentine, Maharaj Singh, Kimberlee A. Gretebeck

College of Nursing Faculty Research and Publications

Physical function declines with aging due to physical and biological changes. The biological process of aging has been associated with increases in systemic inflammation and a greater risk for chronic conditions. In older adults, physical activity aids in maintenance of function. However, the influence of inflammatory biomarkers and adiposity on physical activity and physical function needs to be further explored. Methods: A cross-sectional secondary data analysis from Wave 13 of the Health & Retirement Study (HRS) core biennial data and Venous Blood Study (VBS) was conducted. Structural equation modeling was used to establish the model and test the relationships. Results: …


Transition From College To Professional Workplace: Lived Experiences Of Mid-Level Emergency Care Graduates Working In A Provincial Department Of Health In South Africa, Arthur Mbuyiselo Malgas, Anthonio Oladele Adefuye Jan 2023

Transition From College To Professional Workplace: Lived Experiences Of Mid-Level Emergency Care Graduates Working In A Provincial Department Of Health In South Africa, Arthur Mbuyiselo Malgas, Anthonio Oladele Adefuye

Faculty and Staff Publications

This study aimed to obtain empirical data on the lived experiences of emergency care technicians (ECT) during their transition into the emergency medical service work environment. This qualitative (phenomenological) study used focus group discussions with 26 ECT graduates to obtain verbal statements describing their lived experiences when transiting from college to pre-hospital workplace environments. The three dominant emerging themes were workplace readiness and reception, professional confidence, and resistance in the workplace. The experiences reported regarding workplace readiness and reception were largely negative. The majority of the participants shared that the EMS station they were deployed to had not been ready …


Building Services Engineering January/February 2023 Jan 2023

Building Services Engineering January/February 2023

Building Services Engineering

No abstract provided.


Compensating And Taxing Land Regulations, Seng Wei, Edward Ti Jan 2023

Compensating And Taxing Land Regulations, Seng Wei, Edward Ti

Research Collection Yong Pung How School Of Law

In this article, I synthesise the literature regarding the law and economics approach dealing with compulsory acquisition. Contrary to the status quo, I reason that regulations not amounting to an acquisition, but which adversely affect economic value, should also be compensable from an efficiency lens. This can be accommodated within the existing jurisprudence by recognising that acquisition ‘gains’ can also include environmental amenities, rather than only limiting these to land or property in specie by the acquiring authority. Similarly, where landowners enjoy an uplift in value from regulations, some part of this windfall profit should be taxable. The article takes …


On Beauty, Scholarship, And Function: The Lessons From, And Importance Of, Legal History In The Development Of The Law Of Marine Insurance: [Review Of] Marine Insurance: A Legal History By Rob Merkin, Andrew B.L. Phang Jan 2023

On Beauty, Scholarship, And Function: The Lessons From, And Importance Of, Legal History In The Development Of The Law Of Marine Insurance: [Review Of] Marine Insurance: A Legal History By Rob Merkin, Andrew B.L. Phang

Research Collection Yong Pung How School Of Law

A few words of explanation at the outset are perhaps necessary – if nothing else than to explain the apparently cryptic title of this review essay. What in fact began as a somewhat straightforward review of a book on the history of marine insurance took a wholly unexpected turn and morphed into a general essay on the beauty, scholarship and function of legal history as viewed through the lenses of marine insurance. Indeed, in addition to being a magisterial two-volume history of the law of marine insurance, the present work demonstrates – in the most vividly possible way – at …


Regulating The Corporate Governance Of State-Owned Enterprises In Investment Arbitration, Mark Mclaughlin Jan 2023

Regulating The Corporate Governance Of State-Owned Enterprises In Investment Arbitration, Mark Mclaughlin

Research Collection Yong Pung How School Of Law

The renaissance of sovereign investment is one of the defining economic trends of the 21st century. While many states have benefitted, and continue to benefit, from an influx of state-backed foreign investment, this embrace is not without its hesitancies. Host states are particularly concerned that state-owned enterprises (SOE s) pursue non-commercial policy objectives, maintain lower levels of transparency than their private counterparts, and operate with inferior standards of responsible business conduct. In response, domestic regulators have enacted a series of countermeasures for SOE investment, including requirements that such enterprises must invest on a “commercial basis.” However, the regulation of foreign …


Personal Service Companies And The Tax Avoidance Surcharge In Singapore, Vincent Ooi, Ben Chester Cheong Jan 2023

Personal Service Companies And The Tax Avoidance Surcharge In Singapore, Vincent Ooi, Ben Chester Cheong

Research Collection Yong Pung How School Of Law

Incorporation of personal service companies provide tax and non-tax advantages. With the introduction of a tax avoidance surcharge in Singapore, incorporation for non-tax advantages risks additional “tax costs” if challenged by the revenue authorities, introducing uncertainty and litigation costs. Instead of relying on a GAAR, targeted measures should restrict tax advantages to the first company incorporated by each individual taxpayer.


Cover And Contents Jan 2023

Cover And Contents

Turkish Journal of Physics

No abstract provided.


Cover And Contents Jan 2023

Cover And Contents

Turkish Journal of Physics

No abstract provided.


Cover And Contents Jan 2023

Cover And Contents

Turkish Journal of Physics

No abstract provided.


Shortterm Optical Variability Of 4c 29.45, Aykut Özdönmez Jan 2023

Shortterm Optical Variability Of 4c 29.45, Aykut Özdönmez

Turkish Journal of Physics

We observed the flat-spectrum radio quasar 4C 29.45 in the BVRI optical bands for 39 nights from February 2022 to July 2022 with the T60 telescope at TÜBİTAK National Observatory (TUG) in Turkey. In this study, we aimed to study flux, color, and spectral variability on short timescales. The object was in an active (bright) phase with an average optical R-band brightness of 14.7 mag and was variable in the BVRI bands throughout the monitoring period. We analyzed the flux variability during our observation period, and the variability amplitudes in V, R, and I bands were determined to be 220%, …


Risk At The Boundaries Of Social Work: An Editorial, Rory Crath, Jeremy Dixon, Jo Warner Jan 2023

Risk At The Boundaries Of Social Work: An Editorial, Rory Crath, Jeremy Dixon, Jo Warner

School for Social Work: Faculty Publications

In this editorial we introduce a special thematic collection of articles which focus on how risk operates, or is conceptualised, at the boundaries of social work practice. The collection includes theoretical, empirical, and practice-oriented articles, each of which critically engages with contemporary debates about risk and social work and its complex intersections with boundary making in diverse fields. These fields include social work with older people, child sexual abuse and exploitation, and people with learning disabilities. We begin the editorial with a brief account of how social work can be defined and the competing ideological traditions that underpin differing forms …


Conserved Gene Signatures Shared Among Mapt Mutations Reveal Defects In Calcium Signaling, Miguel A Minaya, Sidhartha Mahali, Abhirami K Iyer, Abdallah M Eteleeb, Rita Martinez, Guangming Huang, John Budde, Sally Temple, Alissa L Nana, William W Seeley, Salvatore Spina, Lea T Grinberg, Oscar Harari, Celeste M Karch Jan 2023

Conserved Gene Signatures Shared Among Mapt Mutations Reveal Defects In Calcium Signaling, Miguel A Minaya, Sidhartha Mahali, Abhirami K Iyer, Abdallah M Eteleeb, Rita Martinez, Guangming Huang, John Budde, Sally Temple, Alissa L Nana, William W Seeley, Salvatore Spina, Lea T Grinberg, Oscar Harari, Celeste M Karch

2020-Current year OA Pubs

No abstract provided.


The Immunology Of Takotsubo Syndrome, Kenji Rowel Q Lim, Douglas L Mann, Tsuneaki Kenzaka, Tomohiro Hayashi Jan 2023

The Immunology Of Takotsubo Syndrome, Kenji Rowel Q Lim, Douglas L Mann, Tsuneaki Kenzaka, Tomohiro Hayashi

2020-Current year OA Pubs

Takotsubo syndrome (TTS) is a disorder characterized by transient cardiac dysfunction with ventricular regional wall motion abnormalities, primarily thought to be caused by the effects of a sudden catecholamine surge on the heart. Although the majority of patients exhibit prompt recovery of their cardiac dysfunction, TTS remains associated with increased mortality rates acutely and at long-term, and there is currently no cure for TTS. Inflammation has been shown to play a key role in determining outcomes in TTS patients, as well as in the early pathogenesis of the disorder. There are also cases of TTS patients that have been successfully …


Training, Supervision, And Experience Of Coaches Offering Digital Guided Self-Help For Mental Health Concerns, Ellen E Fitzsimmons-Craft, Elsa Rojas, Naira Topooco, Gavin N Rackoff, Nur Hani Zainal, Daniel Eisenberg, Jillian Shah, Christina Desage, Denise E Wilfley, Craig Barr Taylor, Michelle G Newman Jan 2023

Training, Supervision, And Experience Of Coaches Offering Digital Guided Self-Help For Mental Health Concerns, Ellen E Fitzsimmons-Craft, Elsa Rojas, Naira Topooco, Gavin N Rackoff, Nur Hani Zainal, Daniel Eisenberg, Jillian Shah, Christina Desage, Denise E Wilfley, Craig Barr Taylor, Michelle G Newman

2020-Current year OA Pubs

Accessible, low-cost intervention options are necessary to address the rise in mental health problems among college students. Digital guided self-help, or coached, programs have been developed to provide such services, with many commercially available. As such, there are a large and growing number of individuals coaching these programs. However, an unmet need is to evaluate and assess best practices for training and supervising individuals in these positions. To this end, we describe how we recruited, trained, and supervised coaches as part of a large randomized controlled trial using a widely available digital commercial platform. Coaches were trained to provide digital …


Outcome Of Covid-19 In Patients With Rheumatic Diseases Treated With Immunosuppressive Drugs, Ali Sobh, Noha Hazem Elnagdy, Mohamed Elegezy, Mohamed Mofreh, Mohamed Tohlob, Ahmad M. Eita, Ragheed Rizk, Ola Eliwa, Marwa H. Elnagdy, Ahmed Elsaeed Abdulgalil Jan 2023

Outcome Of Covid-19 In Patients With Rheumatic Diseases Treated With Immunosuppressive Drugs, Ali Sobh, Noha Hazem Elnagdy, Mohamed Elegezy, Mohamed Mofreh, Mohamed Tohlob, Ahmad M. Eita, Ragheed Rizk, Ola Eliwa, Marwa H. Elnagdy, Ahmed Elsaeed Abdulgalil

Mansoura Medical Journal

Background: Rheumatologic disorders have been significantly impacted by the coronavirus disease 2019 (COVID-19) pandemic. The potential role of immunosuppressive drugs in the presentation, severity and even management of COVID-19 is still questionable. The aim of this work was to study the effect of immunosuppressive drugs on outcome of COVID-19 infection in patients with rheumatic diseases. 109 rheumatic patients (37 pediatrics and 72 adults) taking immunosuppressive treatment with confirmed COVID-19 infection were included in this study. Clinical, laboratory, radiological findings and outcome of these patients were retrospectively retrieved from hospital medical records. Results: The majority of adult cases were rheumatoid arthritis …


Unusual Late Presentation Of Kartagener Syndrome: A Case Report, Abdulhadi H. Al-Mazroea Jan 2023

Unusual Late Presentation Of Kartagener Syndrome: A Case Report, Abdulhadi H. Al-Mazroea

Mansoura Medical Journal

Kartagener's syndrome (KS) is a rare inherited autosomal recessive condition. It comprises of the triad chronic sinusitis, bronchiectasis, and situs inversus. The symptoms are more prevalent in children in the early years of life. We describe a case of a 15-year-old child showing severe respiratory distress with a history of intermittent wet cough and rhinitis for the past six months. The patient was diagnosed with dextrocardia at birth and had no significant medical history since then. Based on his clinical presentation and imaging findings, he was diagnosed with KS that was confirmed by whole-exome sequencing. The patient was managed with …


Evaluation Of Platelet Indices And Low-Density Lipoprotein (Ldl) As Predictors Of Acute Ischemic Stroke Severity And Outcome, Ahmed E. Al-Sharabi, Ashraf A. El-Mitwalli, Yousra M. Tera, Hossam M. Egila Jan 2023

Evaluation Of Platelet Indices And Low-Density Lipoprotein (Ldl) As Predictors Of Acute Ischemic Stroke Severity And Outcome, Ahmed E. Al-Sharabi, Ashraf A. El-Mitwalli, Yousra M. Tera, Hossam M. Egila

Mansoura Medical Journal

Background: Platelets play a role in atherosclerosis, inflammation, and thrombosis. Prothrombotic events, activation, aggregation, and adhesion are all increased by elevated mean platelet volume (MPV) and platelet distribution width (PDW) levels; high low-density lipoprotein (LDL) raises the risk of cardiovascular disease. Aims: Investigate the association between platelet indices, lipid profile, stroke severity, and outcome in patients with acute ischemic stroke. ‎ Subjects and methods: A prospective case-control study involved 100 acute ischemic stroke patients and 100 controls from Mansoura University Hospitals. Patients underwent neurological assessments, including the National Institutes of Health Stroke Scale (NIHSS), modified Rankin Scale (mRS), and Alberta …