Digital Commons Network^™

The Effect Of An Afterschool Makerspace Program On Academic Achievement Of Sixth-Eighth Grade Students, Teresa Lampe

Murray State Theses and Dissertations

This quasi-experimental study investigated the effect of participation in an afterschool makerspace program on middle school students' academic achievement, grades, and school attendance. An experimental group of 237 sixth-eighth grade students participated in an afterschool makerspace program during the 2019-2020, 2020-2021, and 2021-2022 school years. A control group was selected using stratified random sampling of students from the same schools, grades, and special education designation who did not participate. The data included science and math NWEA scores, science and math grades, program attendance, school attendance, and gender. The data were analyzed using an independent t test with a 95% confidence …

An Exploratory Study Of Ergonomics In College Students, Wesley Ryan Tinker

Murray State Theses and Dissertations

Abstract

This study aimed to examine the relationship between poor ergonomic conditions and student physiological discrepancies. This examination provided great insight into students’ daily experiences and concerns for their futures. The methodology used for this study was quantitative as two source data sets were collected and analyzed. The tool REBA was used to measure the specific body angles while students sat working. A survey yielded great results, giving the students an opportunity to subjectively choose options.

This exploratory study allowed the researcher to use quantitative data to answer this study’s research questions. The research questions asked from this study were …

Self-Diagnosis & Pathologizing Normality During The Information Age, Chelsey Eaton

Murray State Theses and Dissertations

Self-diagnosis has become a concern for medical and mental health diagnoses. More people are engaging in self-diagnosis based on information that was obtained from the internet, including websites, social media platforms, and online forums. There are several reasons one may choose to self-diagnose. Some common reasons outlined in research are the desire to fit in with others who share similar characteristics and having a label to explain one’s experiences. Past research has shown that people frequently search for mental health information online, but they may not understand or may misinterpret the information that is found. This study aimed to address …

The Relationship Between Student Performance In English Language Proficiency And Academic Content Assessments, Rosa Wolford

Murray State Theses and Dissertations

As the number of English Learner (EL) students continue to increase in the United States and accountability increases for their growth and achievement in both English language proficiency and state content assessments, it is essential that educational agencies examine the predictive relationships between the assessments to ensure appropriate supports for English Learners are provided. Subsequently, the purpose of this study was to determine if there is a predictive relationship between the WIDA ACCESS Literacy and Overall Composite scores and the TNReady English Language Arts and Mathematics assessments scores of sampled EL students in fourth through twelfth grades among the subgroups …

Higher Education Awareness Amongst Noncommissioned Officers In The United States Army, Amanda Houser

Murray State Theses and Dissertations

Insufficient research exists concerning why active-duty enlisted noncommissioned officers do not pursue education past a high school diploma. Although higher education is becoming a minimum qualification in the civilian world, only 17% of enlisted servicemembers have higher than a high school degree. The purpose of this study is to explore the lived experiences, beliefs, and awareness of Army education benefits and the disconnect between higher education enrollment and active-duty noncommissioned officers. Two-hundred and sixty-five enlisted active-duty noncommissioned officers participated in an online survey and fifty-two noncommissioned officers participated in a one-on-one interview. Using a qualitative, grounded theory research design, both …

Women Pursuing An Agricultural Systems Technology Degree, Tanya Milam

Murray State Theses and Dissertations

Abstract

This phenomenological research study examined the factors influencing women to pursue an Agricultural Systems Technology (AST) degree and their self-efficacy in that field of study. Two research questions guided this study and data was analyzed from interviewing women enrolled in an Agricultural Systems Technology (AST) program at a mid-western university. The resulting four categories of Agricultural Experiences, Aptitude, Support, and Motivation were broken down into themes. The results were also applied to the theoretical framework of self-efficacy associated with career choice theories. Limitations of scope and generalizability indicate that further investigation of this topic is highly recommended.

Keywords: …

Halo Meets Horn: Influence Of Dissonant Information In Impressions, Amber Sanders

Murray State Theses and Dissertations

Abstract

The halo effect is a cognitive bias in impression formation that happens when people assume that when a person has a positive trait, such as physical attractiveness, the rest of their characteristics are also positive, leading to an overall positive perception of that person (Thorndike, 1920; Radeke & Stahelski, 2020). Conversely, the horns effect links together a negative trait, such as unattractiveness, with other seemingly negative traits (e.g., selfishness), leading to an overall negative perception (Radeke & Stahelski, 2020). However, these impression formation heuristics can lead to inaccurate impressions and poor judgments (Baumeister & Vohs, 2007). The current study …

Peer Response And Assistance To Suicidal Thoughts And Behavior In University Students, Lindsey Katherine Hunter

Murray State Theses and Dissertations

Suicide represents the second leading cause of death in adolescents and young adults (CDC, 2022). Many interventions employed on college campus focus on peer support which has been previously related to reductions in suicidal thoughts and behaviors (STB, e.g., suicidal ideation, suicidal plan, suicide attempts), but students may not have the experience needed to increase confidence or knowledge in providing support (Hirsch & Barton, 2011; King et al., 2008). Further, previous research has identified factors including exposure to STB, direct engagement in STB, knowledge, and stigma regarding suicide which have had mixed impact on confidence and helping intentions in supporting …

An Analysis Of P-20 Education At San Ildefonso Pueblo In Northern New Mexico, United States, Martin Edward Strones

Murray State Theses and Dissertations

This research study provides an inquiry by conducting a qualitative analysis of the conditions and issues associated with students at the San Ildefonso Pueblo in Northern New Mexico. For decades the education of San Ildefonso and Native Americans who live in the State of New Mexico has been ignored. This has been just the way it was, that is, until Wilhelmina Yazzie, a Native American, saw her son struggling in an unsatisfactory school system and decided to take action. This case was originally filed in McKinley Country, New Mexico, in 2014, home to largely Native American students for the Navajo …

A Geospatial Analysis Of Crime Hotspots, Campus Safety Measures, And The Campus Community’S Perceived Safety At Murray State University, Rachel Stuckey

Murray State Theses and Dissertations

Murray State University (Murray State) is in far Western Kentucky. Murray State prides itself on being a safe campus for prospective students. In this study spatial analysis was used to analyze the relationship among crime hotspots, campus safety measures, and students’ perception of safety on campus the campus of Murray State. A survey was distributed to students to determine the areas of the campus where students feel safe and unsafe. Geographical Information Systems (GIS) were used to determine the location of crime hotspots over eight years (2014-2022) to measure the spatial relationship between logged crime hotspots and perceived safe and …

Silver Carp Hypophthalmichthys Molitrix Movements In The Lower Cumberland River And Lower Tennessee River, Miranda Belanger

Murray State Theses and Dissertations

The introduction of exotic fishes in freshwater environments has caused significant ecological and economic changes. Silver Carp Hypophthalmichthys molitrix are an invasive species in the United States but are native to large rivers in eastern Asia. This species is expanding its range throughout the Mississippi River basin, beginning with the Cumberland River and Tennessee River drainages. Although Silver Carp movement patterns have been studied in other portions of the Cumberland River and Tennessee River, the lowermost portion of both rivers below Lake Barkley Dam and Kentucky Lake Dam is a unique environment in which the movement of Silver Carp has …

Exploring The Moderating Role Of Psychological Flexibility On The Relationship Between Structural Barriers, Attitudinal Barriers, And Stigma On Mental Health Treatment-Seeking, Hannah Elyse Hays

Murray State Theses and Dissertations

College students face a multitude of stressors that have been found to significantly impact mental health, including symptoms of depression, anxiety, and substance use problems (Hubbard et al., 2018; American College Health Association 2022a; American College Health Association 2022b). Despite a rising concern regarding mental health, over 70% of college students denied seeking mental health treatment in the past year (American College Health Association, 2022b). Psychological flexibility could be an area of intervention because it has been found to be negatively associated with psychological distress and positively associated with mental health service seeking (Christodoulou et al., 2021; Komiya et al., …

Relationship Between Social-Emotional Learning And Post-Secondary Job Satisfaction, Sean Demaree

Murray State Theses and Dissertations

This dissertation aims to respond to two challenges. The first is a gap in literature and research around the impact of social-emotional learning (SEL) beyond graduation from high school. While many studies have been conducted on the impact of SEL in schools, few examine how the use of SEL schools supports students in their post-secondary success. The second challenge centers on the current job market crisis in the Kansas City Metropolitan Area, specifically with job satisfaction and retention of employees. This study invited employees at five large companies in the Kansas City Metropolitan Area to respond to a two-part survey. …

Teacher Perceptions Of The Georgia Agricultural Education Elementary Standards Of Excellence: A Qualitative Study, James Judson

Murray State Theses and Dissertations

This dissertation examines teacher perceptions of the Georgia Standards of Excellence (GSEs) in elementary agricultural education. The study involved a qualitative research design with a sample of 10 elementary agriculture education teachers across multiple schools in Georgia. The research aimed to explore teachers' perceptions of the GSEs, their implementation, and the impact of the standards on their teaching practices and student outcomes. The findings indicate that while teachers generally have positive perceptions of the GSEs, there are also concerns related to the standards' flow from year to year, the use of hard-to-understand vocabulary, and the inclusion of FFA-related content. Additionally, …

The Impact Of Classroom Economies On Teacher Job Satisfaction, Amanda Hutchison

Murray State Theses and Dissertations

The significance of this study lies in its focus on high school teachers' job satisfaction after implementing a classroom economy strategy, with no previous research available on this specific relationship. The study addresses the critical issue of teacher turnover and its financial and educational implications. It also offers valuable insights for teacher preparation programs, colleges and universities, state departments of education, and classroom economy nonprofit companies.

Can Middle School Students Learn Agriculture From Behind A Computer Screen? A Comparative Analysis Case Study Of Online Vs Traditional Middle School Agricultural Courses In Rural Georgia, Roseanna Volz

Murray State Theses and Dissertations

Online education is growing in popularity. Traditional schooling is losing the monopoly of being the only teaching method available to students (Nguyen, 2015). Online learning has evolved throughout the development of online education (Sun & Chen, 2016). Many schools focus on the core content classes for online education like math, science, social studies, and English language arts, but school systems are starting to grow their curricula (Bedard & Knox-Pipes, 2006). This quantitative study was a comparative analysis of an online and traditionally taught agricultural education course. Middle school students completed 12 assignments throughout six weeks. The grades from the assignments …

Histopathological Evaluation Of Onchocerca Volvulus Nodules By Microscopy And By Digital Image Analysis For The Study Of Macrofilaricidal Drug Efficacy, Kerstin Fischer, Bettina Dubben, Linda B Debrah, Janina M Kuehlwein, Arcangelo Ricchiuto, Alexander Y Debrah, Achim Hoerauf, Gary J Weil, Peter U Fischer, Ute Klarmann-Schulz

2020-Current year OA Pubs

BACKGROUND: Novel drugs or drug combinations that kill or permanently sterilize adult

MATERIAL AND METHODS: Two expert microscopists independently assessed 605 nodules by direct microscopy. At least two sections with two different stains hematoxylin & eosin (H&E, APR immunostain) of paraffin-embedded, ethanol-fixed whole-nodule cross-sections were analyzed. After variables were identified prone to observer discrepancies, we performed a second study to compare consolidated results for 100 nodules obtained by the two readers by microscopy and by analysis of scanned, high resolution digital images (20x magnification). The last data set analyzed was a quality panel of 100 nodules that has been previously …

Health Disparities In Aging: Improving Dementia Care For Black Women, Caleigh A Findley, Makayla F Cox, Adam B Lipson, Ratasha Bradley, Kevin N Hascup, Carla Yuede, Erin R Hascup

2020-Current year OA Pubs

In the United States, 80% of surveyed Black patients report experiencing barriers to healthcare for Alzheimer's disease and related dementias (ADRD), delaying the time-sensitive treatment of a progressive neurodegenerative disease. According to the National Institute on Aging, Black study participants are 35% less likely to be given a diagnosis of ADRD than white participants, despite being twice as likely to suffer from ADRD than their white counterparts. Prior analysis of prevalence for sex, race, and ethnicity by the Centers for Disease Control indicated the highest incidence of ADRD in Black women. Older (≥65 years) Black women are at a disproportionately …

The Plasma Virome In Longitudinal Samples From Pregnant Patients, Molly J Stout, Anoop K Brar, Brandi N Herter, Ananda Rankin, Kristine M Wylie

2020-Current year OA Pubs

INTRODUCTION: Nucleic acid from viruses is common in peripheral blood, even in asymptomatic individuals. How physiologic changes of pregnancy impact host-virus dynamics for acute, chronic, and latent viral infections is not well described. Previously we found higher viral diversity in the vagina during pregnancy associated with preterm birth (PTB) and Black race. We hypothesized that higher diversity and viral copy numbers in the plasma would show similar trends.

METHODS: To test this hypothesis, we evaluated longitudinally collected plasma samples from 23 pregnant patients (11 term and 12 preterm) using metagenomic sequencing with ViroCap enrichment to enhance virus detection. Sequence data …

Conserved Gene Signatures Shared Among Mapt Mutations Reveal Defects In Calcium Signaling, Miguel A Minaya, Sidhartha Mahali, Abhirami K Iyer, Abdallah M Eteleeb, Rita Martinez, Guangming Huang, John Budde, Sally Temple, Alissa L Nana, William W Seeley, Salvatore Spina, Lea T Grinberg, Oscar Harari, Celeste M Karch

2020-Current year OA Pubs

No abstract provided.

The Vacc-Seqqc Project: Benchmarking Rna-Seq For Clinical Vaccine Studies, Johannes B Goll, Richard D Head, Et Al.

2020-Current year OA Pubs

[This corrects the article DOI: 10.3389/fimmu.2022.1093242.].

Interactions Of Pathogenic Escherichia Coli With Ceacams, Alaullah Sheikh, James M Fleckenstein

2020-Current year OA Pubs

The pathogenic

Objective Response To Immune Checkpoint Inhibitor Therapy In Nras-Mutant Melanoma: A Systematic Review And Meta-Analysis, Zachary J Jaeger, Neel S Raval, Natalia K A Maverakis, David Y Chen, George Ansstas, Angela Hardi, Lynn A Cornelius

2020-Current year OA Pubs

INTRODUCTION:

METHODS: We performed a comprehensive literature search across several large databases. Inclusion criteria were trials, cohorts, and large case series that analyzed the primary outcome of objective response rate by

RESULTS: Data on 1770 patients from ten articles were pooled for meta-analysis, and the objective response rate to ICIs was calculated to compare

DISCUSSION: In this meta-analysis evaluating the impact of

Psychosocial Work Environment Stressors For School Staff During The Covid-19 Pandemic: Barriers And Facilitators For Supporting Wellbeing, Liz R Rolf, Liz Vestal, Ashley C Moore, Nikole Lobb Dougherty, Nancy Mueller, Jason G Newland

2020-Current year OA Pubs

INTRODUCTION: After periods of remote and/or hybrid learning as a result of the COVID-19 global pandemic, the return to in-person learning has been beneficial for both students and teachers, but it has not been without challenges. This study was designed to assess the impact of the return to in-person learning on the school experience, and efforts made to ease the transition in furthering a positive in-person learning environment.

MATERIALS AND METHODS: We conducted a series of listening sessions with 4 stakeholder groups: students (

RESULTS: Three main themes emerged around school staff experiences: (1) increased levels of stress and anxiety …

Review Of Factors Resulting In Systemic Biases In The Screening, Assessment, And Treatment Of Individuals At Clinical High-Risk For Psychosis In The United States, Miranda A Bridgwater, Emily Petti, Maksim Giljen, Leeann Akouri-Shan, Joseph S Deluca, Pamela Rakhshan Rouhakhtar, Caroline Millar, Nicole R Karcher, Elizabeth A Martin, Jordan Devylder, Deidre Anglin, Raquel Williams, Lauren M Ellman, Vijay A Mittal, Jason Schiffman

2020-Current year OA Pubs

BACKGROUND: Since its inception, research in the clinical high-risk (CHR) phase of psychosis has included identifying and exploring the impact of relevant socio-demographic factors. Employing a narrative review approach and highlighting work from the United States, sociocultural and contextual factors potentially affecting the screening, assessment, and service utilization of youth at CHR were reviewed from the current literature.

RESULTS: Existing literature suggests that contextual factors impact the predictive performance of widely used psychosis-risk screening tools and may introduce systemic bias and challenges to differential diagnosis in clinical assessment. Factors reviewed include racialized identity, discrimination, neighborhood context, trauma, immigration status, gender …

3′-Sulfated Lewisa/C: An Oncofetal Epitope Associated With Metaplastic And Oncogenic Plasticity Of The Gastrointestinal Foregut, Koushik K Das, Jeffrey W Brown

2020-Current year OA Pubs

Metaplasia, dysplasia, and cancer arise from normal epithelia

A Systematic Framework For Predictive Biomarkers In Immune Effector Cell-Associated Neurotoxicity Syndrome, Omar H Butt, Alice Y Zhou, Beau M Ances, John F Dipersio, Armin Ghobadi

2020-Current year OA Pubs

Chimeric antigen receptor (CAR)-T cell therapy has revolutionized the management of several life-threatening malignancies, often achieving durable sustained responses. The number of patients treated with this new class of cell-based therapy, along with the number of Food and Drug Association (FDA) approved indications, are growing significantly. Unfortunately Immune Effector Cell-Associated Neurotoxicity Syndrome (ICANS) can often occur after treatment with CAR-T cells, and severe ICANS can be associated with significant morbidity and mortality. Current standard treatments are mainly steroids and supportive care, highlighting the need for early identification. In the last several years, a range of predictive biomarkers have been proposed …

Exploring The Villalta Scale To Capture Postthrombotic Syndrome Using Alternative Approaches: A Subanalysis Of The Attract Trial, Cristina T Pop, Chu-Shu Gu, Suresh Vedantham, Jean-Philippe Galanaud, Susan R Kahn

2020-Current year OA Pubs

BACKGROUND: Clinical trials that evaluated interventions to prevent postthrombotic syndrome (PTS) used the Villalta scale (VS) to define PTS, but there is a lack of consistency in its use.

OBJECTIVES: This study aimed to improve the ability to identify patients with clinically meaningful PTS after DVT in participants of the ATTRACT trial.

METHODS: We conducted a post hoc exploratory analysis of 691 patients from the ATTRACT study, a randomized trial evaluating the effectiveness of pharmacomechanical thrombolysis to prevent PTS in proximal deep vein thrombosis. We compared 8 VS approaches to classify patients with or without PTS in terms of their …

Predicting Continuous Amyloid Pet Values With Csf And Plasma Aβ42/Aβ40, Julie K Wisch, Brian A Gordon, Anna H Boerwinkle, Patrick H Luckett, James G Bollinger, Vitaliy Ovod, Yan Li, Rachel L Henson, Tim West, Mathew R Meyer, Kristopher M Kirmess, Tammie L S Benzinger, Anne M Fagan, John C Morris, Randall J Bateman, Beau M Ances, Suzanne E Schindler

2020-Current year OA Pubs

INTRODUCTION: Continuous measures of amyloid burden as measured by positron emission tomography (PET) are being used increasingly to stage Alzheimer's disease (AD). This study examined whether cerebrospinal fluid (CSF) and plasma amyloid beta (Aβ)42/Aβ40 could predict continuous values for amyloid PET.

METHODS: CSF Aβ42 and Aβ40 were measured with automated immunoassays. Plasma Aβ42 and Aβ40 were measured with an immunoprecipitation-mass spectrometry assay. Amyloid PET was performed with Pittsburgh compound B (PiB). The continuous relationships of CSF and plasma Aβ42/Aβ40 with amyloid PET burden were modeled.

RESULTS: Most participants were cognitively normal (427 of 491 [87%]) and the mean age was …

Glaucoma And Microglia-Induced Neuroinflammation, Makoto Ishikawa, Yukitoshi Izumi, Kota Sato, Taimu Sato, Charles F Zorumski, Hiroshi Kunikata, Toru Nakazawa

2020-Current year OA Pubs

Glaucoma is a multifactorial neurodegenerative disease characterized by a progressive optic neuropathy resulting in visual field defects. Elevated intraocular pressure (IOP) is the greatest risk factor for the development of glaucoma, and IOP reduction therapy is the only treatment currently available. However, there are many cases in which retinal degeneration progresses despite sufficient control of IOP. Therefore, it is important to elucidate the pathophysiology of glaucoma that is resistant to current IOP lowering therapies. Experiments using animal glaucoma models show the relationships between microglial neuroinflammatory responses and damage of retinal ganglion cells (RGCs). Inhibition of neuroinflammatory pathways associated with microglial …