Digital Commons Network^™

Should Environmental Protection Be Through Anthropocentric Rights?, Christen Maccone

Pace Environmental Law Review

Environmental constitutional rights are increasingly used as a strategy to protect the environment, with more than seventy countries acknowledging environmental rights in their constitutions. However, constitutions are inherently anthropocentric, making environmental rights created therein of- ten inseparable from human rights. This paper will examine how environ- mental constitutional rights are insufficient due to the anthropocentric nature of constitutions and argue for the need for a more biocentric approach.

The Constitutional Public Trust In A Warming World, Sean Lyness

Pace Environmental Law Review

The public trust doctrine—a state-specific doctrine that entrusts certain natural resources to the state to hold for the public—most often exists as a common law doctrine. But a handful of states have constitutionalized their version of the public trust. A growing body of jurisprudential evidence shows the constitutional public trust in action—or not—against climate change. This Article examines these cases brought by governmental plaintiffs—states and local governments—investigating whether constitutionalizing the public trust has made a difference. Although the results are nascent, early signs suggest that a constitutional public trust can result in more comprehensive and aggressive law- suits when wielded …

The Green Amendment: Assessing The Latest Tool In The Environmental Tool Belt, Carolyn Drell, Mia Petrucci

Pace Environmental Law Review

In the new edition of Maya K. van Rossum’s book, The Green Amendment: The People’s Fight for a Clean, Safe, and Healthy Environment, she presents the case for adopting green amendments protecting environmental rights into state constitutions and the Federal Constitution. This book review examines van Rossum’s arguments and raises legal concerns that prevent green amendments from providing a silver bullet solution to environmental harms. Despite these concerns that will likely resonate with practitioners, van Rossum increases the accessibility to the topic of green amendments for a wider audience, which is ultimately a net win for environmental advocacy.

Stable Complexity: Verbal Inflection In Prominent And Frequent Environments, Lukas Denk

Linguistics ETDs

Despite presenting challenges for speakers, complex linguistic features such as lexically conditioned inflection (LCI) persist across different languages. LCI forms part of not entirely predictable paradigms which require lexeme-specific knowledge to master. Moreover, LCI remains one of the oldest morphological phenomena in certain languages. Previous research has linked the persistence of such complexity to language-external factors like geographic and social circumstances of speech communities.

This dissertation delves into the question whether language-internal properties are associated with the distribution of inflectional complexity. LCI is compared with other inflectional paradigms across 41 genetically and geographically distant languages. The study shows that LCI …

Dryland Vegetation Mapping Using High Spatial-Temporal Resolution Satellite Imagery In New Mexico: A Comparison Of Phenological Time-Series Transformation Methods, Pratistha Sharma

Geography ETDs

New Mexico's drylands are undergoing notable vegetation changes due to rising aridity, higher temperatures, and shifts in precipitation with changing climate. Mapping drylands through remote sensing is challenging compared to mesic systems due to the irregular patterns of rainfall-driven phenology and weaker vegetation absorption signals. This study aims to enhance vegetation mapping in New Mexico, utilizing a high-resolution, frequently revisited PlanetScope dataset with multispectral capabilities, specifically chosen for its suitability for time-series analysis. The challenge with high spatial and temporal data lies in the overwhelming volume, leading to issues like the curse of dimensionality, overfitting, data redundancy, collinearity, and visualization …

Regulation Of Mrna And Circrna As A Cause And Consequence Of Aging In Caenorhabditis Elegans, Rebekah Napier-Jameson

Biological Sciences Theses and Dissertations

A role for RNA binding proteins in regulating lifespan has emerged. We identified a pair of neuronal RBPs, exc-7 and mbl-1, which display synthetic lifespan defects. Such a strong synthetic phenotype represented an opportunity to use transcriptomics to search for potential causative targets that are synthetically regulated. We identified a small handful of genes synthetically dysregulated in double mutants and systematically tested each candidate gene for functional contribution to the exc-7; mbl-1 lifespan phenotype. We identified one such gene, the ion transporter nhx-6, which is highly upregulated in double mutants. Overexpression of nhx-6 causes reduced lifespan, and deletion …

The Effects Of Full Spectrum Hemp Oil On Extinction Of Stress Enhanced Fear Learning In A Rodent Model Of Ptsd, Tiphanie Chanel

Psychology ETDs

There are only 2 FDA-approved treatments for Post-Traumatic Stress Disorder (PTSD) despite the overwhelming evidence of the need for safer and more effective treatments. For example, roughly 50% of treatment seeking patients with PTSD experience relief from conventional pharmaceutical medications and only one third experience full remission. The Cannabis plant is a promising novel treatment for PTSD for several reasons. The endocannabinoid system plays a role in stress, emotion, cognition, suicidal phenotypes, fear memory consolidation, retrieval and reconsolidation and extinction. Cannabidiol (CBD), one of the most widely studied phytocannabinoids found in the Cannabis plant, has both anxiolytic and antidepressant qualities. …

Efficacy Of The Hepatojugular Reflux Test, Adrienne Irmiter, Cheyanne Dolan, Sarah Edrington

Physician Assistant Capstones, 2020-current

No abstract provided.

"A Special Cause Of Corrupting Their Youth": The Long History Of Censorship, Hysteria, And The Representation Of Queer Desire In Literature, Kenia Torres

Student Theses and Dissertations

This thesis will focus on queer representation in literature, going all the way back to the works of Milton and Shakespeare and include an exploration of contemporary text Gender Queer by Maia Kobabe. I will trace queer representation back to these authors from the canon to show that queer representation in literature and societies’ hysterical reaction to it are neither new nor emergent. Chapter 1 addresses the trending outrage towards books that include LGBTQ+ representation, framing it as a “new” and “emergent” occurrence. Chapter 2 refutes the claims that LGBTQ+ representation is either of those things by introducing Milton’s angels— …

Portrayals Of Gender And Race In Instagram Advertising: An Exploratory Content Analysis, Taylor Moore

Honors College Theses

Race and gender stereotyping is a longstanding problem in the world of advertising. This research utilized content and statistical analysis to answer three questions regarding race and gender stereotyping in Instagram advertising: (1) what portrayals are being shown? (2) how are these portrayals being shown? And (3) are diverse advertisements reinforcing or challenging stereotypes? Tweny advertisements were chosen off Instagram to analyze. Through an analysis of literature on the topic, a code book defining race, person of color, sex, gender, and gender expression was created. Using these variables and classifying the ads as a stereotype/counterstereotype/neutral, allowed for the creation of …

Math Vocabulary & Number Sense: Instructional Strategies For Upper Elementary English Learning Students In The Math Classroom, Matt J. Cavanaugh

Doctorate in Education

Recent studies show that English learning students are a growing population within the United States school system. Language barriers have been shown to negatively influence reading scores as well as math scores, and math scores are a predictor of future academic success in many subject areas. This qualitative action research study demonstrates the difficulties many upper-elementary English learning students have understanding number sense (numeracy) in a math classroom setting in Minnesota, United States. The purpose of this study was to explore whether intentional teaching of math vocabulary could alleviate the difficulties upper-elementary English learning students have in understanding, applying, and …

Bridging The Gaps: Listening To Early Education Leaders As Minnesota Public School Districts Work To Align Their Pre-K And K-12 Systems, Lisa A. Willman

Doctorate in Education

This qualitative study employed a grounded-theory approach to examine how Minnesota public schools align their pre-K to their K-12 systems. One-time, on-line interviews with eight early education leaders probed their districts’ catalyst for aligning the systems, how they continued the work after it was initiated, what successes and challenges they encountered, and their recommendations for other districts planning to do such alignment. Data were gathered using the built-in video-recording option in Google Meet, which also created closed captions and a printed transcript of the information. The resulting data were then analyzed via ATLAS.ti using eight main categories derived from Kauerz …

Roadside Lidar Data Processing For Intelligent Transportation System, Md Parvez Mollah

Computer Science ETDs

Roadside LiDAR (Light Detection and Ranging) sensors are recently being explored for Intelligent Transportation System aiming at safer and faster traffic management and vehicular operations. However, massive data volume, occlusion, and limited viewing angles are significant obstacles to the widespread use of roadside LiDARs. In this dissertation, we address three major challenges to enable applications of Intelligent Transportation System through roadside LiDAR data: (i) real-time transmission of the massive point-cloud data from the roadside LiDAR devices to the cloud using 5G network, (ii) mitigating sensor occlusion problem to increase coverage and detect events occurred in occluded regions of a sensor, …

Exploring The Use Of Time Delay As A Pragmatic Cue In Text Messaging, Nicklas Phillips

Masters Theses, 2020-current

Text messaging is often used as a stand-in for face to face communication. While texting mimics the rapid back and forth, turn taking nature of oral conversation, it lacks many of the pragmatic cues conversationalists ordinarily rely on to establish common ground and inform their understanding of sometimes nonliteral meaning conveyed to them. To get around this hurdle, texters have developed sets of textisms. These are specific cues that can be used to make up for the lack of pragmatic information in the texting environment. Examples include emoji, emoticons, and punctuation. This is an experimental study exploring whether time can …

Correlation Analysis Between Agronomic Character And Yield Of Padjadjaran Maize Hybrids At Medium And High Population Densities, Yuyun Yuwariah, Qinthara Nail Haysa, Damara Bakti Muhammad, Dedi Ruswandi, Fiky Yulianto Wicaksono

Jurnal Kultivasi

Maize is a prospective food commodity that developed in Indonesia. The use of hybrid corn gives better yield than open-pollinated varieties. Spacing management in hybrid maize production can reduce competition between plants, so that the plant canopy and roots can grow optimally. This research aimed to compare the differences in the phenotypic performance of the agronomic characters of Padjadjaran maize hybrid, determine the dominant agronomic characteristics, and determine the correlation between the growth and yield characteristics at medium- and high-population densities. The experiment was carried out from December 2021 until May 2022 at Sanggar Penelitian, Latihan dan Pengembangan Pertanian (SPLPP) …

Isolation And Characterization Of Bacteriophages From Fish Tank Samples, Oluwaseyi Oluwagbeminiyi Oladele-Ajose

Electronic Theses and Dissertations

Bacteriophages (phages) are viral obligate intracellular parasites that infect bacteria. Research has been carried out on alternative treatment plans for bacterial infections due to the increase in antibiotic resistance. Phages have been proposed as an alternative to antibiotics. This research focused on the isolation and characterization of bacteria from small aquariums. A total of 42 bacterial isolates were isolated from seven different fish tank water samples and were tested to determine if they possessed phages. Spot plaque assay revealed presence of lytic phage for only one of the isolated bacterial strains, which was determined to belong to Enterobacteriaceae family based …

From Andy’S Room To Big City And Nickelodeon: Extending The Brand To New Consumers Through Alternate Broadcasts Of Live Sports Entertainment, Cody T. Havard, Timothy D. Ryan

Findings in Sport, Hospitality, Entertainment, and Event Management

The Walt Disney Company aired the Toy Story Football Funday on Sunday, October 1^st, 2023. A live game between the Jacksonville Jaguars and Atlanta Falcons played in London, England aired on ESPN+ while the Toy Story-themed alternate broadcast aired on Disney+. This game followed multiple alternate broadcasts of NFL games by Nickelodeon and an NHL game themed after Big City Greens on the Disney Channel, Disney XD, and Disney+. This analysis paper discusses the use of these alternate broadcasts in an attempt to attract younger viewers and expand consumers for leagues and live sports entertainment. A brief …

Parsons, Edgar Athletics Oral History, Cindy Spiro

General Athletics

Ed Parsons was a 1934 graduated of Pacific and athlete

Digital Journeys: A Narrative Inquiry Into The Experiences Of Third- Grade Through Fifth-Grade General Education Teachers Implementing Instructional Technology In Northern California, Erin Layng

Doctor of Education Program Dissertations

The problem studied was the utilization of instructional technology in elementary classrooms, from third-grade through fifth-grade, and how teachers experience the use of technology in teaching methods and student learning. The purpose of this qualitative narrative inquiry was to understand the experiences of third-grade through fifth-grade teachers regarding the implementation of instructional technology in their classrooms. The study's timing captured teachers' views on technology before, during, and after the 2020-2021 academic year, which was heavily impacted by the COVID-19 pandemic and distance learning. Qualitative narrative inquiry allowed for a rich exploration of the teachers' experiences, with results of the study …

Physical Therapists And Physical Therapy Assistants’ Readiness Levels To Deliver Telehealth Services: A Survey Analysis, Bhavana Raja, Alicia Rabena-Amen, David Gillette, Preeti Oza, Todd E. Davenport

Internet Journal of Allied Health Sciences and Practice

Purpose: The purpose of this study was to investigate physical therapists (PT) and physical therapy assistants’ (PTA) readiness to deliver telehealth (TH) services during COVID-19 pandemic. Method: IRB approved this survey analysis study. The Modified Maryland TH Readiness Assessment Tool (mMTRAT) was distributed by email to all licensed PTs and PTAs in California in October 2020. One-way analysis of variance (ANOVA) was used to compare between-groups differences for continuous demographic data. Pearson chi-square analysis was used to assess between-group distributions of categorical data. The statistical significance of between-groups median mMTRAT scores was assessed using the Mann-Whitney U test. Statistical significance …

The Object Play Of Young Children On The Autism Spectrum: A Narrative Review Of Strengths-Based Literature, Sharon Eva

Internet Journal of Allied Health Sciences and Practice

Purpose: The play in young children with autism has been historically seen as deficits-based, with a focus on the limitations of autistic object play. More recently, there has been a shift towards a strengths-based view of autistic object play, where their play preferences and skills are viewed as vehicles for meaningful engagement and as having potential for learning. The aims of this narrative review are two-fold: to identify themes in the existing literature regarding the object play of young children with autism; and, to summarize the existing literature specifically examining object play in young autistic children from a strengths-based point …

Remote Teleassessment And Telerehabilitation Of A Comprehensive Exercise Training Protocol For Older Adults: Design And Methodology Of A Usability Protocol, Savitha Subramaniam, Spyros Kitsiou, Tanvi Bhatt

Internet Journal of Allied Health Sciences and Practice

ABSTRACT

Purpose: The design, usability, safety, and feasibility of a telehealth protocol comprising teleassessment and tele rehabilitation to evaluate and improve physical and cognitive function among older adults was assessed. Methods: Healthy older adults (n=23) participated in a pre-post tele-assessment of a 4-week (3 sessions/week) telerehabilitation session. Tele-assessment was performed to evaluate balance, gait function, and cognition. Tele-rehabilitation sessions comprised of balance games, dancing, dual-tasking, yoga, and tai-chi exercises. Results: There were no adverse events reported to indicate concerns with the safety of the current telehealth protocol. Conclusion: The proposed telehealth protocol to assess and improve physical and cognitive function …

An Integrated Strategy To Evaluate Active Substances Of Astragali Radix-Carthami Flos Combination On The Treatment Of Cerebral Ischemia Reperfusion Injury Based On Tqsm Polypharmacokinetics And Pharmacodynamics, Qiang Zeng, Chang Li, Shouchao Xu, Yu He

Journal of Food and Drug Analysis

As a classic herb pair, Astragali Radix-Carthami Flos (AR-CF) has revealed good biological activity in the treatment of cerebral ischemia/reperfusion injury (CI/RI), which remained to be further clarified together with the underlying efficacy related compounds for material basis. In this study, the nine formulations were obtained by L₉(3⁴) orthogonal array design of four active fractions (saponin and flavonoid extracted from AR, safflower yellow and safflower red extracted from CF). The concentrations of eleven components and the levels of four biochemical indicators in rat plasma were continuously detected after intragastric administration of nine formulations, respectively. The collected …

Dehulled Adlay (Coix Lachryma-Jobi L.) Ameliorates Hepatic Gluconeogenesis And Steatosis In Streptozotocin/High-Fat Diet-Induced Diabetic Rats, Shing-Hwa Liu, Wan-Hsin Wu, Huei-Ping Tzeng, Wenchang Chiang, Meng-Tsan Chiang

Journal of Food and Drug Analysis

Adlay (Coix lachryma-jobi L.) is a traditional Chinese herbal medicine with various biological activities. We investigated the anti-diabetic effects of different parts of adlay seeds, including polished adlay (PA), adlay bran (AB) and dehulled adlay (DA) in a streptozotocin (STZ)/high fat diet (HFD) diabetic rat model (DM). DM rats supplemented with or without PA (43%), AB (3%), or DA (46%) diet for 8 weeks. The plasma glucose and insulin levels and the insulin resistance index (HOMA-IR) were increased in DM group; among the three adlay diets, DA has the best effects attenuating all of these alterations in DM …

Biological And Clinical Significance Of The Age-Rage Axis In The Aggressiveness And Prognosis Of Prostate Cancer, Shih-Hong Khoo, Pei-Ru Wu, Kun-Tu Yeh, Shih-Lan Hsu, Chi-Hao Wu

Journal of Food and Drug Analysis

Dietary factors and chronic hyperglycemia are linked to the formation of advanced glycation end products (AGEs) and prostate cancer (PCa) risk. The activation of the receptor for AGEs (RAGE) acts as a bridge between various RAGE ligands and certain malignancies. This study showed that the interaction of AGEs and RAGE promoted PCa cell proliferation, invasion, and autophagy-mediated survival in response to chemotherapeutic agents. RAGE-overexpressed PCa cells underwent epithelial-mesenchymal transition and showed increased cancer stem cell-like properties. In mouse xenograft models, RAGE-overexpressed cells showed more substantial tumorigenic capacity than parental cells, whereas RAGE knockdown decreased tumorigenicity. The clinical data validated a …

Abundance Of Prevotella Copri In Gut Microbiota Is Inversely Related To A Healthy Diet In Patients With Type 2 Diabetes, Chih-Yiu Tsai, Po-Yu Liu, Meng-Chuan Huang, Chiao-I Chang, Hsin-Yun Chen, Yu-Hsien Chou, Chi-Neu Tsai, Chia-Hung Lin

Journal of Food and Drug Analysis

While the gut microbiota is known to be influenced by habitual food intake, this relationship is seldom explored in type 2 diabetes patients. This study aims to investigate the relationship between dietary patterns and gut microbial species abundance in 113 type 2 diabetes patients (mean age, 58 years; body mass index, 29.1; glycohemoglobin [HbA1c], 8.1%). We analyzed the gut microbiota using 16S amplicon sequencing, and all patients were catogorized into either the Bacteroides enterotype (57.5%, n = 65) or the Prevotella enterotype (42.5%, n = 48) using the partitioning around medoids clustering algorithm, based on the most representative genera. Patients …

Therapeutic Effects Of Orally Administration Of Viable And Inactivated Probiotic Strains Against Murine Urinary Tract Infection, Vo Thi Hong Van, Zhen-Shu Liu, Yueh Jen Hsieh, Wei-Chen Shiu, Bo-Yuan Chen, Yu-We Ku, Po-Wen Chen

Journal of Food and Drug Analysis

Urinary tract infections (UTIs) are highly prevalent bacterial infections that pose significant health risks. Specific probiotic strains have been recommended for UTI control and management of antibiotic resistance. Otherwise, paraprobiotics, defined as inactivated probiotic cells, offer potential advantages by minimizing risks associated with live microorganisms. However, the effectiveness of heat-killed probiotic strains against UTIs remains uncertain. Additionally, lactoferrin (LF), an iron-binding glycoprotein, exhibits immunomodulatory, antimicrobial, and anti-inflammatory properties. Recently, we had developed recombinant LF-expression probiotics, which can display considerate antibacterial activities against select food-borne pathogens in vitro. Thus, the present study aimed to evaluate the antibacterial activities of heat-killed natural …

Combining The Tyrosine Kinase Inhibitor Cabozantinib And The Mtorc1/2 Inhibitor Sapanisertib Blocks Erk Pathway Activity And Suppresses Tumor Growth In Renal Cell Carcinoma., Yige Wu, Siqi Chen, Xiaolu Yang, Kazuhito Sato, Preet Lal, Yuefan Wang, Andrew T Shinkle, Michael C Wendl, Tina M Primeau, Yanyan Zhao, Alanna Gould, Hua Sun, Jacqueline L Mudd, Jeremy Hoog, R Jay Mashl, Matthew A Wyczalkowski, Chia-Kuei Mo, Ruiyang Liu, John M Herndon, Sherri R Davies, Di Liu, Xi Ding, Yvonne A Evrard, Bryan E Welm, David Lum, Mei Yee Koh, Alana L Welm, Jeffrey Chuang, Jeffrey A Moscow, Funda Meric-Bernstam, Ramaswamy Govindan, Shunqiang Li, James Hsieh, Ryan C Fields, Kian-Huat Lim, Cynthia X Ma, Hui Zhang, Li Ding, Feng Chen

Faculty Research 2023

UNLABELLED: Current treatment approaches for renal cell carcinoma (RCC) face challenges in achieving durable tumor responses due to tumor heterogeneity and drug resistance. Combination therapies that leverage tumor molecular profiles could offer an avenue for enhancing treatment efficacy and addressing the limitations of current therapies. To identify effective strategies for treating RCC, we selected ten drugs guided by tumor biology to test in six RCC patient-derived xenograft (PDX) models. The multitargeted tyrosine kinase inhibitor (TKI) cabozantinib and mTORC1/2 inhibitor sapanisertib emerged as the most effective drugs, particularly when combined. The combination demonstrated favorable tolerability and inhibited tumor growth or induced …

The Association Between Prenatal Acetaminophen Use And Adhd Development In Childhood, Jocelyne Blanco, Erika Mccarthy, Justin Gambini

Doctor of Medical Science (DMSc)

Background: The purpose of this article is to produce a review of the literature on a recently growing topic of interest. We believe the widespread use of acetaminophen in pregnancy makes the rising concern for acetaminophen use in pregnancy and the development of childhood attention deficit hyperactivity disorder (ADHD) a national public health matter. The mechanism of action of acetaminophen, the pathophysiology of drug transfer through the placental barrier, and the most up-to-date research studies were analyzed with the goal of bringing clarity and promoting healthy pregnancies for all.

Methods: PubMed, PLOS One, and Google Scholar served as the cornerstone …

The Constitutional Ambition Of Black Liberation, Paul A. Gowder

DePaul Journal for Social Justice

No abstract provided.