Digital Commons Network^™

Effects Of Antiresorptive Medications On Tooth Root Formation And Tooth Eruption In Paediatric Patients, Yuki Arai, Jeryl D English, Noriaki Ono, Wanida Ono

Faculty, Staff and Student Publications

Tooth eruption is a pivotal milestone for children's growth and development. This process involves with the formation of the tooth root, the periodontal ligament (PDL) and the alveolar bone, as the tooth crown penetrates the bone and gingiva to enter the oral cavity. This review aims to outline current knowledge of the adverse dental effects of antiresorptive medications. Recently, paediatric indications for antiresorptive medications, such as bisphosphonates (BPs), have emerged, and these agents are increasingly used in children and adolescents to cure pathological bone resorption associated with bone diseases and cancers. Since tooth eruption is accompanied by osteoclastic bone resorption, …

Role Of The Immune System In Liver Transplantation And Its Implications For Therapeutic Interventions, Guanrong Chen, Xin Hu, Yingchen Huang, Xiaonan Xiang, Sheng Pan, Ronggao Chen, Xiao Xu

Faculty, Staff and Student Publications

Liver transplantation (LT) stands as the gold standard for treating end-stage liver disease and hepatocellular carcinoma, yet postoperative complications continue to impact survival rates. The liver's unique immune system, governed by a microenvironment of diverse immune cells, is disrupted during processes like ischemia-reperfusion injury posttransplantation, leading to immune imbalance, inflammation, and subsequent complications. In the posttransplantation period, immune cells within the liver collaboratively foster a tolerant environment, crucial for immune tolerance and liver regeneration. While clinical trials exploring cell therapy for LT complications exist, a comprehensive summary is lacking. This review provides an insight into the intricacies of the liver's …

Investigation Of Av Operational Issues Using Simulation Equipment, Zainab Abidemi Saka, Samuel Labi

Center for Connected and Automated Transportation

To help mitigate road fatalities due to human error, transportation stakeholders are turning to advanced driver assistance systems and autonomous vehicle (AV) development. However, the stakeholders continue to seek assurance of the safety performance of this new technology. This is often done using simulation testing of AV sensors and other platforms for simulation (microsimulation of AV movements, AV testing in a cab driving simulator, at AV test tracks, AV-dedicated road networks and in-service roads). Simulation is particularly important for the perception module of AV systems. Perception is a key module that typically uses light detection and ranging (LIDAR) sensors and …

A Plea To The Republic Of Korea’S Young Economists, Yeomin Yoon

KAUPA Letters

No abstract provided.

Kaupa Letters: Volume 11, Issue 2, Korean American University Professors Association

KAUPA Letters

No abstract provided.

Prevalence Of Temporomandibular Disorders (Tmd) In Obesity Patients: A Systematic Review And Meta-Analysis, Giuseppe Minervini, Rocco Franco, Maria Maddalena Marrapodi, Luis Eduardo Almeida, Vincenzo Ronsivalle, Marco Cicciù

School of Dentistry Faculty Research and Publications

Objective

Obesity is a growing epidemic in the world. It increases the risk for severe health conditions, including diabetes, heart disease and stroke. Recent research has found that obesity is associated with an increased risk for temporomandibular disorders (TMDs). The purpose of this literature review with meta-analysis is to analyse the possible association between obesity and temporomandibular disorders.

Materials and Methods

Pubmed, Web of Science and Lilacs were systematically searched until 01/03/2000. Articles dealing with TMD and obesity were selected, and numbers that might be useful in the meta-analysis were extracted.

Results

Fifty articles were chosen after using all three …

The Information Literacy Class As Theatrical Performance: A Qualitative Study Of Academic Librarians’ Understanding Of Their Teacher Identity, Mark Aaron Polger

Publications and Research

This qualitative study examines how academic librarians understand, conceptualize, and describe their teacher identity. The role of the academic librarian has greatly changed due to the advent of information technology. Traditionally, they were generalists, who were responsible for selecting and maintaining library collections. Academic librarian roles have evolved into web developers, information literacy (IL) instructors, emerging technology innovators, marketing and outreach coordinators, open education resources (OER) advocates, and scholarly communication experts. This research investigates the academic librarian as teacher phenomenon, how they describe their professional identity as teachers, the skills, knowledge, and competencies they teach, and their beliefs of how …

“And I’M Going To Destroy You.”: Persona And Gender Performativity In Ernest Hemingway’S The Garden Of Eden, Nicole Minton

UNLV Theses, Dissertations, Professional Papers, and Capstones

While debate of Ernest Hemingway’s authorial masculine persona in connection to The Garden of Eden has been a point of interest in literary scholarship, no single work has tied together theory of gender performativity to persona. A borderline parodic display of masculine adventure has encouraged a one-dimensional view of Hemingway, who is viewed by audiences as the pinnacle of masculinity. However, this image is complicated by the publication of Eden, which reveals an author interested in gender and sexual identity fluidity. Rarely has a single text called into question so controversially an author’s public image. Eden showcases an empathetic …

Application Of Biochar For Antibiotic-Free Nutrient Recovery From Source-Separated Human Urine, Sayeda Ummeh Masrura

UNLV Theses, Dissertations, Professional Papers, and Capstones

In recent years, the application of biochar as a soil amendment has gained attention as a potential solution for nutrient management and environmental remediation. Biochar, a carbon-rich material produced through the pyrolysis of biomass under oxygen-limited conditions, exhibits unique physicochemical properties making it an effective sorbent for nutrients and contaminants. Its high surface area, porosity, and stability provide an ideal matrix for nutrient retention and release, as well as the immobilization of pollutants. One area of particular interest is the application of biochar for nutrient recovery from source-separated human urine. Source separation of urine has gained momentum as a sustainable …

Optical And Electrical Interfaces For Biological Structures, Mehdi Bandali

Boise State University Theses and Dissertations

This dissertation presents novel solutions for recording optical and electrical data from biological structures. CHAPTER ONE discusses the 16×16 Time correlated SPAD image array I developed in a 180 nm HV CMOS process for single-molecule localization super-resolution microscopy (SRM). This image array has a maximum frame rate of 80 MHz and a fill factor of 17.4 %. To demonstrate SRM with this imaging array, we localized gold nanoparticle displacement at 40 nm. CHAPTER TWO discusses stimulation artifacts' time and frequency domain characteristics and potential strategies for canceling this interference on neural recording. CHAPTER THREE discusses an artifact-resilient neural recording front-end …

Role Of Mechanical Signaling In Bone Tissue, Scott Aaron Birks

Boise State University Theses and Dissertations

As the global population ages and life expectancy continues to rise, osteoporosis continues to be a growing worldwide health concern. The International Osteoporosis Foundation reports 1 in 3 women over the age of 50 years and 1 in 5 men worldwide will experience osteoporotic fractures in their lifetime, costing between 5 and 6.5 trillion USD annually in Canada, Europe, and the United States alone. The need for preventative measures to reduce age-related bone loss is clear, not only to improve quality of life for countless individuals but also to relieve the economic burden this condition imposes.

Exercise is a proven …

Balancing Societal Demands For Agricultural Land: Insights, Innovations, And Conservation Priorities, Sarah Halperin

Boise State University Theses and Dissertations

With an increasing global population and the effects of climate change and biodiversity loss intensifying, society faces many challenges in reconciling conflicting demands for the landscape. Covering roughly half of the land area of the United States, agricultural land is in direct competition with other land uses and will likely play an important role in addressing these important conservation challenges. In this dissertation, we used well-supported existing methodologies and principles from ecosystem services, message framing, and biodiversity conservation to create knowledge about how to better protect agricultural lands. We conducted our study in the Treasure Valley, Idaho, where the issue …

Flow Electrode Capacitive Deionization Using Mxene Suspension Electrodes For Energy Efficient Water Remediation, Naqsh E. Mansoor

Boise State University Theses and Dissertations

The growing global demand for clean water, coupled with increasing concerns around aquatic pollution, necessitate the development of high performing and energy-efficient technologies for wastewater remediation. Capacitive Deionization (CDI) has emerged as a promising electrochemical method for desalination and removal of contaminants from various water sources. Despite its potential, CDI faces a significant bottleneck concerning the selection and optimization of suitable electrode materials. The choice of electrode materials critically influences the performance and efficiency of the CDI system, with the quest for an ideal material remaining a challenging and ongoing research endeavor. This dissertation explores potential of using MXene materials …

Open Finance: Regulatory Challenges Of The Evolution Of Data Sharing Arrangements In The Financial Sector, Nydia Remolina Leon

Research Collection Yong Pung How School Of Law

In recent years, open banking has emerged as a new form of financial intermediation, allowing third party developers to build applications and services around financial institutions. By using the financial institution's data and infrastructure through open Application Programming Interfaces (APIs), a variety of actors-including fintech companies, Bigtechs, and the traditional players in the financial system-can develop new products and services that ultimately promote innovation, competition and financial inclusion while improving consumers' experiences. The concept of open banking evolved to open finance to illustrate the possibilities of adding to the picture all types of data-driven financial products. Focusing on the opportunities …

The Effect Of Nitroglycerin In Testicular Histopathology, Reproductive Hormones And Testicular Oxidative Stress In Adolescent Rats, Volkan Koşal, Çağlar Okulmuş, Yılmaz Koçak, Ömer Faruk Keleş, Nesrin Ceylan, Yıldıray Başbuğan

Mansoura Veterinary Medical Journal

Background: Nitroglycerin (NTG) exerts a vasodilation effect by acting on vascular smooth muscles. The exact impact of vasodilation on the testes is not fully understood. Objectives: This study aimed to investigate the effects of NTG on the testes before the onset of spermatogenesis and reproductive activity in adolescent rats. Methods: An Average of 45 days male Albino Wistar rats were used. Two groups were formed: an adolescent control group and an adolescent NTG group (10 mg/kg, 5 d). Results: At the end of the study, testicular oxidative stress (malondialdehyde /MDA, catalase/ CAT, advanced oxidation protein products /AOPP, and nitric oxide/ …

Exploring The Effectiveness Of Telehealth Adolescents' Interventions On Sleep: A Meta-Analysis, Youmna Hakoum

Online Theses and Dissertations

The purpose of this meta-analysis was to explore the effectiveness of any telehealth interventions that report sleep outcomes on adolescents, ages 11-20 years old. It was hypothesized that most studies will favor telehealth treatment, regardless of type of treatment, and will present medium to high effect sizes sleep improvements. The following databases were searched to determine any research articles published after 2000 and present as of 8 July 2023: PsycINFO, PubMed, and Cochrane. In total, 15 studies, five pre-post and ten Randomized Controlled Trials (RCT), fit the inclusion and exclusion criteria and were analyzed. Subjective (self-report) and objective (actigraphy based) …

Placental Co-Culture Model Reveals Listeria Monocytogenes Utilization Of Monocytes For Vertical Transmission, Breanna Mackenzie Amelunke

Online Theses and Dissertations

Listeria monocytogenes is an opportunistic pathogen that can cross the protective placental barrier and infect the fetus, leading to congenital disabilities or death. Extracellular L. monocytogenes infection of the placenta has been well studied; however, the bacteria have not been observed translocating this barrier intracellularly. As an intracellular pathogen, L. monocytogenes could infect phagocytic cells that can be transported across the placental barrier. A novel cell co-culture system comprised of BeWo and HPVEC cell lines was established to model the human placental barrier. Barrier integrity was confirmed using immunostaining of tight junctions and a FITC-dextran permeability assay. The model was …

Environmental Exposure Effects To Humans And Trends Of Harmful Algal Blooms In Nebraska, Ericka Sanders

Capstone Experience: Master of Public Health

Harmful algae blooms (HAB) are becoming more of a human health concern. Humans are exposed to harmful algae blooms from freshwater bodies used for recreational activities. The presence of harmful algae blooms has been increasing across the United States. Aerosol, dermal, and ingestion routes of exposure are ways humans can develop an illness when around a HAB. Environmental exposure to humans above 8 ppb per liter of surface water can cause mild to severe symptoms and, in rare cases, may be fatal. Exposure can be acute or chronic. The Nebraska Department of Environment and Energy (NDEE) has implemented a monitoring …

Androgen Receptor: A Complex Therapeutic Target In Breast Cancer, Sarah Tinuade Asemota

Theses and Dissertations (ETD)

Breast cancer is classified based on the expression of three markers estrogen receptor (ER), progesterone receptor, and human epidermal growth factor receptor (HER2). Breast cancers that express these targets are classified as hormone receptor (HR) positive breast cancer and the tumors that lack the expression of these markers are classified as triple negative breast cancer (TNBC). Though HR-positive breast cancer is treated with hormonal and cyclin-dependent kinase 4/6 targeted therapies, the cancer relapses and becomes resistant to the treatment options. Androgen receptor (AR) that is expressed in over 90\% of ER-positive breast cancer and in 20\% of TNBC is a …

The Therapeutic Role Of Lm11a-31 (A P75ntr Modulator) In The Outcome Of Ischemic Stroke And Hiv-1 Pathogenesis, Golnoush Mirzahosseini

Theses and Dissertations (ETD)

The objective of this research project is to explore the potential therapeutic role of LM11A-31 in both ischemic stroke and human immunodeficiency virus-1 (HIV-1) infection. There are limited treatment options for ischemic stroke, with tissue plasminogen activator (tPA) being the only effective medication and a narrow administration window, which is also accompanied with the high incidence of ischemic stroke in HIV-1 infected individuals. Therefore, it is critical to explore an effective therapeutic agent to address the urgent medical need. LM11A-31 is a p75 neurotrophin receptor (p75NTR) modulator and is orally bioavailable, and it can penetrate the intact blood-brain barrier (BBB). …

The Role Of Tcr Engagement Strength In Antitumor Cd8 T Cell Exhaustion, Xin Lan

Theses and Dissertations (ETD)

Durability of an antitumor immune response is mediated in part by the persistence of progenitor exhausted CD8 T cells (Tpex). Tpex serve as a source for the pool of effector T cells that tend to have a short lifespan or eventually become dysfunctional in uncleared tumors. In contrast to the short-lived feature of their daughter cells, Tpex are able to preserve their quantity and developmental potential through a process of self-renewal. Previous research has demonstrated that Tpex can even self-renew in the absence of their cognate antigen. However, it remains unknown how T cell receptor (TCR) engagement impacts the self-renewal …

Understanding The Host Cellular Response To Astrovirus Infection, Theresa Mary Taggart Bub

Theses and Dissertations (ETD)

Astrovirus is a non-enveloped positive-sense single-stranded RNA virus that infects the small intestine and causes gastrointestinal disease in most hosts. However, in immunocompromised patients, astrovirus can infect the brain, causing encephalitis and death. Here, we characterize astrovirus induction of replication organelles and dysregulation of cellular processes. It is known that autophagy can play a key role in the viral lifecycle, from entry to egress, and can be either pro-virus or pro-host depending on the virus. RNA viruses often exploit autophagy machinery to create double membrane vesicles (DMVs) as sites of replication and to protect viral RNAs from detection by innate …

Exogenous Mitochondrial Transfer And Il-6: Modulating Adipocyte Metabolism In Obesity-Associated Dysregulation, Soumi Mazumdar

Theses and Dissertations (ETD)

Obesity, a global health epidemic, poses significant challenges to public well-being due to its complex interplay of metabolic dysregulation, inflammation, and associated comorbidities. Mitochondria, central to ATP production, lipid metabolism, and thermogenesis, play a crucial role in modulating white adipose tissue metabolism. This thesis explores an innovative strategy for addressing mitochondrial dysfunction in obesity which is a critical aspect of this multifactorial problem. The research findings presented herein uncover the impact of introducing exogenous mitochondria into NIH3T3-L1 adipocytes on various aspects of adipocyte function. The key discoveries of this study include a remarkable upregulation of energy expenditure genes, notably Ucp1, …

Investigating Potential Quantitative Trait Loci For Susceptibility To Experimental Autoimmune Encephalomyelitis In The Bxd Family Of Mice, Margaret Caroline Danehy

Theses and Dissertations (ETD)

Multiple Sclerosis is an autoimmune inflammatory condition that causes disability, axonal damage in the central nervous system, and eventual paralysis. One of the main risk factors for developing MS is genetics, with recent studies identifying multiple risk alleles associated the major histocompatibility complex. By utilizing the BXD family of mice, we investigated genetic factors that affect a BXD strain’s susceptibility to EAE, an inducible disease model for MS. We induced EAE in several BXD mice strains via an emulsion of complete Freund’s adjuvant and MOG35-55, and then measured disease severity in each strain. From there, we measured incidence rate of …

Enhancing Recovery With The Use Of Animals, Christina Martinez

Capstone Projects and Master's Theses

Avenues is a program designed to help adults lead happier and more productive lives by overcoming mental health and chemical dependency challenges. The problem is, participants are not fully prepared for independent living following these programs. The plan was to provide participants a therapeutic approach to gaining hands-on experience while combating symptoms of mental illness with the use of animals, with hopes that participants would be better prepared for life after leaving the program. If the project met the expected outcome, the agency would see a lower rate of participants returning to the program and a higher success rate of …

650 Words, Anne Gregg

A Midwestern Review: A Magazine of the Arts and Issues at DePauw University

Anne Gregg is a writer and poet from Northwest Indiana. She is also the Editor-In-Chief of a Midwestern Review. Anne Gregg is an English writing major and has been published numerous times across the centuries, but most of her work has been lost to time.

Expanding Recognition And Inclusion Of Animal-Free Organic Agriculture In The Sustainable Agriculture Movement, Mona Seymour

Urban and Environmental Studies Faculty Works

Animal-free organic agriculture resides at the margins of sustainable agriculture discourse, practice, and imaginaries, which center animal-based forms of farming. However, the concerns and goals of sustainable agriculture are overwhelmingly consistent with those of many forms of animal-free organic agriculture (AFOA), described as organic farming sans animal production, labor, and byproducts. Despite this sidelining, AFOA has great potential to contribute to a more robust sustainable agriculture movement. In order to emphasize the continuities between animal-based and animal-free sustainable agriculture, this Perspective identifies a number of key similarities between animal-free and animal-based sustainable farming, including mutual foci on soil health and …

A New Approach To Synthetic Image Evaluation, Majid Memari

Dissertations

This study is dedicated to enhancing the effectiveness of Optical Character Recognition (OCR) systems, with a special emphasis on Arabic handwritten digit recognition. The choice to focus on Arabic handwritten digits is twofold: first, there has been relatively less research conducted in this area compared to its English counterparts; second, the recognition of Arabic handwritten digits presents more challenges due to the inherent similarities between different Arabic digits.OCR systems, engineered to decipher both printed and handwritten text, often face difficulties in accurately identifying low-quality or distorted handwritten text. The quality of the input image and the complexity of the text …

Nature And Nurture: Comparing Mouse Behavior In Classic Versus Revised Anxiety-Like And Social Behavioral Assays In Genetically Or Environmentally Defined Groups, Janet Ronquillo, Michael T. Nguyen, Linnea Y. Rothi, Trung-Dan Bui-Tu, Jocelyn Yang, Lindsay R. Halladay

Psychology

Widely used rodent anxiety assays like the elevated plus maze (EPM) and the open field test (OFT) are conflated with rodents' natural preference for dark over light environments or protected over open spaces. The EPM and OFT have been used for decades but are often criticized by behavioral scientists. Years ago, two revised anxiety assays were designed to improve upon the “classic” tests by excluding the possibility to avoid or escape aversion. The 3-D radial arm maze (3DR) and the 3-D open field test (3Doft) utilize continual motivational conflict to better model anxiety; each consist of an open space connected …

Vascular Flora And Rare Plant Modeling Of The Walls Of Jericho Forever Wild Tract, Jackson County, Alabama, Garrett Billings

Masters Theses and Doctoral Dissertations

A floristic inventory in the Walls of Jericho Forever Wild Tract was conducted during the 2021-2023 growing seasons. The Walls of Jericho Forever Wild Tract is a 5,142 ha protected area in Jackson County, Alabama. In total, 32 collection trips were made for a total of ~56 field days, resulting in 709 species, representing 372 genera in 125 families. Forty species of conservation concern were documented, including 12 S1 and 17 S2 species. Eighty-five (12%) of these species were non-native. The top three most represented families were Asteraceae (14%), Poaceae (9%) and Cyperaceae (7%). Additionally, we modeled suitable habitat using …