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Articles 2281 - 2310 of 24881
Full-Text Articles in Entire DC Network
The Quiet And Other Fantastical Tales, Emily Nicole Cerda
The Quiet And Other Fantastical Tales, Emily Nicole Cerda
Theses and Dissertations
This thesis briefly discusses the genres and subgenres of speculative fiction—focusing on fantasy, horror, and science fiction—and is primarily a short story collection that also includes a few novel chapters. The critical introduction delves into the present and overly complex subgenre categorization methods, how and why new subgenres are created, and provides simple definitions for the main genres of speculative fiction and fantasy subgenres.
The subgenres that will be discussed through either a short story, novel chapter(s), or definition include, but are not limited to: fairytales, portal fantasy, paranormal romance, dark fantasy, historical fantasy, magical realism, epic fantasy, mythic fiction, …
Aedes Aegypti Host Preference On Canines Versus Human Volatile Skin Compounds, Melissa Bernadette Rosalez
Aedes Aegypti Host Preference On Canines Versus Human Volatile Skin Compounds, Melissa Bernadette Rosalez
Theses and Dissertations
It is critical to understand how Aedes aegypti mosquitoes detect hosts through cues such as volatile skin compounds. In South Texas, evidence suggests that this mosquito is showing a feeding preference for canines over humans. This shift may impact the transmission of Dirofilaria immitis, canine heart worms, in local dog populations. Our study is set to explore Ae. Aegypti attraction to hosts using canine and human volatile compounds. Volatile skin compounds will be collected using a volatile collection system. Compounds will be analyzed using gas chromatography/mass spectrometry. It is anticipated that the main volatile skin compounds amongst humans are nonanal, …
The Wackiness Of Wacky World, Michael Dan Mccormick
The Wackiness Of Wacky World, Michael Dan Mccormick
Theses and Dissertations
This critical introduction takes a closer look at the situations presented in my manuscript “Wacky World” and offer insight on the actions seen from the main character. This insight is meant to clear confusion as to whether or not the character can be viewed as a heroic figure and explore his personality to draw conclusions. “Wacky World”, a full-length play, tells the story of a man with an obsession with a defunct theme park and the deranged actions that he takes in order to prevent its demolition.
I explore the topic on whether or not sympathy …
Growth Rates, Morphology, And Potential For Mariculture Of The Southern Population Of Crassostrea Virginica In The Lower Laguna Madre, Texas, Jerad Lee Fuelling
Growth Rates, Morphology, And Potential For Mariculture Of The Southern Population Of Crassostrea Virginica In The Lower Laguna Madre, Texas, Jerad Lee Fuelling
Theses and Dissertations
The Eastern Oyster also known as Crassostrea virginica, is an important resource here in the United States. Historically, this species has been overfished, poorly managed, and plagued by disease. Oyster mariculture is a growing industry here in the United States and is a sustainable solution to producing oysters. Texas has become the last coastal state to legalize oyster mariculture which means there is now a vast coastline with many unique bay systems that are open to this industry. One bay system that is particularly unique is the Lower Laguna Madre which is a hypersaline lagoon. Little is known about …
Electrolysis Degradation Of Cyanuric Acid In Wastewater At Cu/Go Cathodes, Chioma Chinwe Nwakanobi
Electrolysis Degradation Of Cyanuric Acid In Wastewater At Cu/Go Cathodes, Chioma Chinwe Nwakanobi
Theses and Dissertations
This work evaluates the development of electrochemical processes for the oxidative degradation of persistent organic chemicals in waste waters, specifically the oxidation of cyanuric acid in the presence of NaCl at Cu/GO cathodes and Ti anodes. The experiment used a graphene oxide doped copper mesh cathode to examine different concentrations of cyanuric acid (30 mg/L, 40 mg/L, and 50 mg/L) and various concentrations of NaCl electrolyte (0.007mol/L, 0.03mol/L, 0.07mol/L, 0.1mol/L, and 0.2mol/L). In addition, the effect of pH (2, 4, 6, and 8), and applied current (0.200A, 0.150A and 0.100A) were studied. The Cu/GO electrode played a central role in …
Enhancing Time Series Hashing Performance Via Deep Orthogonal Hashing, Mahmudul Hasan Robin
Enhancing Time Series Hashing Performance Via Deep Orthogonal Hashing, Mahmudul Hasan Robin
Theses and Dissertations
Deep hashing has been widely used for efficient retrieval and classification of high-dimensional data like images and text. However, its application to time series data is still challenging due to the data’s temporal nature. To tackle this issue, a new deep hashing method has been proposed that generates efficient hash codes and enhances the time series hashing performance using a ResNet model with Orthohash (Cosine Similarity Loss). The proposed method uses one loss architecture while using ResNet model for efficient hashing. It uses the Character Trajectories dataset to extract discriminative features from the time series data. These features are then …
Comparing Socioeconomic Status To Educational Diagnosis Of Serious Emotional Disturbances: A Linear Analysis Of Texas Data, Cristina Rangel
Comparing Socioeconomic Status To Educational Diagnosis Of Serious Emotional Disturbances: A Linear Analysis Of Texas Data, Cristina Rangel
Theses and Dissertations
This dissertation was prepared to determine if a correlation existed between a student’s poverty level and an educational diagnosis of serious emotional disturbance. I hypothesize that students at or under the United States’ definition of poverty are more likely to exhibit signs and symptoms of a serious emotional disturbance and therefore be diagnosed and placed in special education. Both federal data (i.e., poverty levels) and Texas data (i.e., dx of SED) were compared to determine correlation and directionality. TEA combines districts into 20 regions. Special education placement data is publicly available on State databases. Federal poverty levels are available …
A Combinatorial Proof Of Supercranks For Partitions With A Fixed Number Of Parts, Jacob J. Gutierrez
A Combinatorial Proof Of Supercranks For Partitions With A Fixed Number Of Parts, Jacob J. Gutierrez
Theses and Dissertations
In a previous paper by Eichhorn and Kronholm, a selection of supercranks for p(n,m) was established by generating functions. In this paper we will reprove this result with combinatorial witnesses for the selection of supercranks via integer lattice points.
Effects Of Short-Term Pesticides Exposure On Swimming Behavior, Tissue Morphology, Oxidative-Nitrative Stress, Antioxidant Expression, And Cellular Apoptosis In Kidneys Of Goldfish, Esmirna Cantú
Theses and Dissertations
The prevalence of pesticides in the aquatic environment continues to increase due to anthropogenic activities and poses a threat to aquatic organisms. The aim of this study was to determine the short-term exposure (one-week) of pesticide mixtures (metolachlor, linuron, isoproturon, tebucanazole, alconifen, atrazine, pendimethalin; azinphos-methyl) on swimming behaviors, kidney morphology, and expression of nitrotyrosine protein (NTP), dinitrophenyl protein (DNP), superoxide dismutase (SOD), catalase (CAT), renin, and cellular apoptosis in goldfish (Carassius auratus). Results indicated that both low- and high-dose pesticide mixtures decreased the distance swimming behavior. Histological analysis showed pesticide exposure alters kidney morphology. DNP, NTP, and renin expressions, and …
Mano De Obra: Exploring Processes And Materiality In Artwork, Karla Gabriela De La Fuente
Mano De Obra: Exploring Processes And Materiality In Artwork, Karla Gabriela De La Fuente
Theses and Dissertations
This thesis paper examines the theoretical derivatives and artistic influences that drive the artist’s ongoing series of works exploring the human experience of the working class in the border region of South Texas and beyond. Through the use of found objects, organic regional materials, adopted and adapted processes; the artist creates artwork that teeters on a tightrope between sweet, subtle naivety, and sudden, robust spoonfuls of truth. The artwork has an emphasis on the materiality, and the parallel between the “Mano de Obra” of the artist at work and that of the working class of our communities.
Synthesis Of Bacterial Glycerophospholipids For Biomembrane Model Studies: A Means To Advanced Biofuels, Felix Adulley
Synthesis Of Bacterial Glycerophospholipids For Biomembrane Model Studies: A Means To Advanced Biofuels, Felix Adulley
Electronic Theses and Dissertations
To reduce reliance on fossil fuels, sustainable biofuels are being pursued, especially advanced biofuels like 1-butanol that have higher energy content and greater compatibility with existing infrastructure than ethanol. A persistent challenge is the yield-limiting toxicity of biofuels and process solvents, such as tetrahydrofuran, to the microbes that ferment biomass into biofuel. The cell membrane is a focal point of toxicity, and understanding how it interacts with fuels and solvents is key to improving yield. Phospholipid bilayers are the core of biomembranes, and model biomembranes of defined composition provide the ideal platform for biophysical studies. To this end, glycerophospholipids characteristic …
Once Upon Online: Conversations With Professional Storytellers About Adapting From In-Person To Virtual Storytelling Performance, Leticia Pizzino
Once Upon Online: Conversations With Professional Storytellers About Adapting From In-Person To Virtual Storytelling Performance, Leticia Pizzino
Electronic Theses and Dissertations
This study examines how professional storytellers negotiated a new storytelling stage—the videoconference platform—as they pivoted their careers during mandated shutdowns due to COVID-19. An examination of the literature reveals extremely limited research involving either professional storytellers or live virtual storytelling. After interviewing five professional storytellers, I analyzed their stories through narrative inquiry. Analysis revealed that the storytellers negotiated the limitations and affordances of Zoom and adapted their storytelling to successfully connect with their audiences. Through crafting a narrative of their stories, I was able to represent their emotions, unique experiences, and abilities to adapt to the online environment. Their stories …
Intestinal Microbiome, Fecal Fermentation Profile, And Health Indices In Hiv Infected Men Versus Non-Infected Controls, Mary Andreae, Mary C. Andreae Mrs
Intestinal Microbiome, Fecal Fermentation Profile, And Health Indices In Hiv Infected Men Versus Non-Infected Controls, Mary Andreae, Mary C. Andreae Mrs
Electronic Theses and Dissertations
Many HIV-positive (HIV+) males on Highly Active Anti-Retroviral Therapy (HAART) experience metabolic abnormalities, including Non-Alcoholic Fatty Liver Disease (NAFLD) and lipodystrophy. The intestinal microbiota and short chain fatty acids (SCFA), participate in bidirectional communication with their host. Dysbiosis in HIV+ males on HAART demonstrate a Prevotella-rich enterotype shaped by multiple factors including, medications, adiposity, diet, intestinal permeability, and lifestyle; our objective was to investigate these factors. 19 HIV+ and 21 HIV- males were enrolled. BMI and hip-to-waist ratio (H:W) were obtained, and FibroScan for liver health. Intestinal permeability markers Claudin-21, flagellin, and intestinal fatty acid binding protein (IFABP) in …
Effect Of Animated Stories On Pain Intensity And Physiological Parameters Among Post-Operative Children., Sara Sayed Abdalla
Effect Of Animated Stories On Pain Intensity And Physiological Parameters Among Post-Operative Children., Sara Sayed Abdalla
Nursing
No abstract provided.
Effect Of Celery (Apium Graveolens L.) Microgreens On Drosophila Melanogaster, Mohamad Agus Salim, Muhammad Subandi, Yeni Yuniarti
Effect Of Celery (Apium Graveolens L.) Microgreens On Drosophila Melanogaster, Mohamad Agus Salim, Muhammad Subandi, Yeni Yuniarti
Baghdad Science Journal
Celery (Apium graveolens L. ; family : Apiaceae) was often used as a spice in daily food. However, this plant contains many antioxidant compounds useful for attenuating neurodegenerative disorders including Parkinson's disease. Planting celery in the form of microgreens harvested 15 days was expected to increase the content of bioactive compounds. In the current study, we intended to evaluate the neuromodulatory potential of methanol extract of celery microgreens on fruit flies (Drosophila melanogaster Meigen : family Drosophilidae ; ordo : Diptera) which were exposed to paraquat. Neuroprotective capacity was assessed by survival rate, locomotor performance, lipid peroxidation and dopamine content …
Microbial Quality Of Paddy Fields At Alfurat Alawsat Area, Iraq And The Effect Of Milling Process On The Rice Contamination Level, Abeer S. Alhendi, Aqeel M. Ali, Abeer K. Mohammed
Microbial Quality Of Paddy Fields At Alfurat Alawsat Area, Iraq And The Effect Of Milling Process On The Rice Contamination Level, Abeer S. Alhendi, Aqeel M. Ali, Abeer K. Mohammed
Baghdad Science Journal
Fifty-Four paddy samples, 45 soil samples, and nine irrigation water samples of some paddy fields at Alfurat Alawsat Area, Iraq were collected to investigate the microbial quality including total count bacteria (TCB), molds and yeast, total coliform (TC), and E. coli bacteria. Paddy samples were processed at the laboratory level to produce rice at 32 and 36 whiteness, and the microbial quality of the produced rice was conducted too. The results showed that all irrigation water samples were overpassed the FDA limit for E. coli. All paddy samples were exceeded the good limit of TCB, but no sample exceeded the …
Gene Expression And Methylation Levels Of Pcsk9 Gene In Iraqi Patients With Coronary Artery Disease, Marwa M. Al-Attar, Salwa J. Al-Awadi Al-Awadi, Shaimaa Y. Abdulfattah
Gene Expression And Methylation Levels Of Pcsk9 Gene In Iraqi Patients With Coronary Artery Disease, Marwa M. Al-Attar, Salwa J. Al-Awadi Al-Awadi, Shaimaa Y. Abdulfattah
Baghdad Science Journal
The expression of the Proprotein Convertase Subtilisin/Kexin Type 9 gene (PCSK9) is inextricably related to lipid levels and a risk of atherosclerotic coronary artery disease (ASCAD). The present study aims to measure the quantity of PCSK9 gene expression and the effect of methylation on its expression level taking part in the pathogenesis of acute coronary artery disorder. A current study included 150 subjects from the Iraqi population, 100 ASCAD patients and 50 healthy controls. The concentration of PCSK9 in each serum sample was determined by the ELISA technique, the expression levels of the PCSK9 gene in whole blood were estimated …
In Vivo Evaluation The Efficiency Of Nitazoxanide With Cationic Gemini Surfactant On Cryptosporidiosis, Zeinab Ahmed, Eman M. Kandeel, Hagar F. Abdelmaksoud, Tarek Aboushousha, Entsar E. Badr
In Vivo Evaluation The Efficiency Of Nitazoxanide With Cationic Gemini Surfactant On Cryptosporidiosis, Zeinab Ahmed, Eman M. Kandeel, Hagar F. Abdelmaksoud, Tarek Aboushousha, Entsar E. Badr
Baghdad Science Journal
Infection with cryptosporidiosis endangers the lives of many people with immunodeficiency, especially HIV patients. Nitazoxanide is one of the main therapeutic drugs used to treat cryptosporidiosis. However, it is poorly soluble in water, which restricts its usefulness and efficacy in immunocompromised patients. Surfactants have an amphiphilic character which indicates their ability to improve the water solubility of the hydrophobic drugs. Our research concerns the synthesis of new cationic Gemini surfactants that have the ability to improve the solubility of the drug Nanazoxide. So, we synthesized cationic Gemini surfactants. N1,N1,N3,N3-tetramethyl-N1,N3-bis(2-octadecanamidoethyl)propane-1,3-diaminium bromide (CGSPS18) and 2,2‘-(ethane-1,2-diylbis(oxy))bis(N-(2-octadecanamidoethyl)-N,N-dimethyl-2-oxoethane-1-aminium) dichloride (CGSES18) and the detection of their …
The Gptjudge: Justice In A Generative Ai World, Maura R. Grossman, Paul W. Grimm, Daniel G. Brown, Molly (Yiming) Xu
The Gptjudge: Justice In A Generative Ai World, Maura R. Grossman, Paul W. Grimm, Daniel G. Brown, Molly (Yiming) Xu
Duke Law & Technology Review
Generative AI (“GenAI”) systems such as ChatGPT recently have developed to the point where they can produce computer-generated text and images that are difficult to differentiate from human-generated text and images. Similarly, evidentiary materials such as documents, videos, and audio recordings that are AI-generated are becoming increasingly difficult to differentiate from those that are not AI-generated. These technological advancements present significant challenges to parties, their counsel, and the courts in determining whether evidence is authentic or fake. Moreover, the explosive proliferation and use of GenAI applications raises concerns about whether litigation costs will dramatically increase as parties are forced to …
Parent Workshop On Young Children's Emotional Development, Margarita Camacho
Parent Workshop On Young Children's Emotional Development, Margarita Camacho
Capstone Projects and Master's Theses
My capstone project focuses on parents with preschool-aged children. At this age, children feel their emotions before they can recognize what they mean, and it is difficult for them to self-regulate their emotions. Executive function abilities, as well as language abilities, are some of the potential reasons for the difficulties. Research has demonstrated that the first five years of life are crucial for children's emotional development. According to Chronis-Tuscano et al. (2016), to be able to regulate emotions and respond to them effectively, the use of executive functioning skills as well as several cognitive processors are required. Also, as Chronis-Tuscano …
A Word Of Warning: Educational Activists And Public Instruction Conspiracy Theories, David Philip San Juan
A Word Of Warning: Educational Activists And Public Instruction Conspiracy Theories, David Philip San Juan
Dissertations
By utilizing a qualitative approach of educational criticism and connoisseurship, the purpose of this study was to explore the intentions and motivations, processes and strategies, and implications and outcomes of educational activists that work to expose and/or debunk a public instruction conspiracy theory. Data were collected through the interviews and observations of four participants that were educational activists that had worked to expose and/or debunk a public instruction conspiracy theory. Their related literature and artifacts such as various online and traditional publications, social media posts, and audiovisual materials were also collected and transcribed. Data were analyzed with numerous rounds of …
Historical Archives Reveal Record Rainfall And Severe Flooding In December 1867 Resulting From An Atmospheric River And Snowmelt, Western Washington, Usa, Daniel G. Gavin, Patrick J. Bartlein, Cary J. Mock
Historical Archives Reveal Record Rainfall And Severe Flooding In December 1867 Resulting From An Atmospheric River And Snowmelt, Western Washington, Usa, Daniel G. Gavin, Patrick J. Bartlein, Cary J. Mock
Faculty Publications
The flooding of 1861-1862 in California and Oregon is the most severe flood event documented in the far western USA and stands as a benchmark for a worst-case atmospheric-river flooding event. In western Washington, historical data are sparser, and 19th-century flood events have consequently not been well documented. We found that rainfall observations from five locations spanning western Washington had no detectable bias when compared to nearby 20th and 21st-century comparator stations. Time series of the four-day precipitation sum revealed an event in December 1867 that was greater than any of the last century at three locations, and in the …
Exploring Teachers’ Reflections And Narratives Of Negative Language, Maya Khemlani David, Ameer Ali, Francisco Perlas Dumanig, Muhammad Hassan Abbasi
Exploring Teachers’ Reflections And Narratives Of Negative Language, Maya Khemlani David, Ameer Ali, Francisco Perlas Dumanig, Muhammad Hassan Abbasi
Journal of English and Applied Linguistics
Language is used to communicate and express feelings and emotions. In the teaching context, teachers use language to share knowledge and information with students. Teachers’ use of negative language, such as duffer, stupid, and lazy, may result in students feeling mistreated, discouraged, and worthless. Such language can also negatively affect students’ cognitive processes, feelings, and emotions and blunt their curiosity, and their interest in performing better may be reduced. Although much of the previous research has demonstrated the cause-effect relation between negative teacher talk and students’ unsatisfactory performance, none of the studies, to the best of our knowledge, explored teachers’ …
Magnetic Resonance Imaging Of Macrophage Response To Radiation Therapy, Harrison Yang, Brock Howerton, Logan Brown, Tadahide Izumi, Dennis C. Cheek, Jason Anthony Brandon, Francesc Marti, Roberto Gedaly, Reuben Adatorwovor, Fanny Chapelin
Magnetic Resonance Imaging Of Macrophage Response To Radiation Therapy, Harrison Yang, Brock Howerton, Logan Brown, Tadahide Izumi, Dennis C. Cheek, Jason Anthony Brandon, Francesc Marti, Roberto Gedaly, Reuben Adatorwovor, Fanny Chapelin
Markey Cancer Center Faculty Publications
Background: Magnetic resonance imaging (MRI) is a non-invasive imaging modality which, in conjunction with biopsies, provide a qualitative assessment of tumor response to treatment. Intravenous injection of contrast agents such as fluorine (19F) nanoemulsions labels systemic macrophages, which can, then, be tracked in real time with MRI. This method can provide quantifiable insights into the behavior of tumor-associated macrophages (TAMs) in the tumor microenvironment and macrophage recruitment during therapy.
Methods: Female mice received mammary fat pad injections of murine breast or colon cancer cell lines. The mice then received an intravenous 19F nanoemulsion injection, followed by a baseline 19F MRI. …
Design And Characterization Of A Novel Eef2k Degrader With Potent Therapeutic Efficacy Against Triple-Negative Breast Cancer, Changxin Zhong, Rongfeng Zhu, Ting Jiang, Sheng Tian, Xiaobao Zhao, Xiaoya Wan, Shilong Jiang, Zonglin Chen, Rong Gong, Linhao He, Jin-Ming Yang, Na Ye, Yan Cheng
Design And Characterization Of A Novel Eef2k Degrader With Potent Therapeutic Efficacy Against Triple-Negative Breast Cancer, Changxin Zhong, Rongfeng Zhu, Ting Jiang, Sheng Tian, Xiaobao Zhao, Xiaoya Wan, Shilong Jiang, Zonglin Chen, Rong Gong, Linhao He, Jin-Ming Yang, Na Ye, Yan Cheng
Markey Cancer Center Faculty Publications
Dysregulated eEF2K expression is implicated in the pathogenesis of many human cancers, including triple-negative breast cancer (TNBC), making it a plausible therapeutic target. However, specific eEF2K inhibitors with potent anti-cancer activity have not been available so far. Targeted protein degradation has emerged as a new strategy for drug discovery. In this study, a novel small molecule chemical is designed and synthesized, named as compound C1, which shows potent activity in degrading eEF2K. C1 selectively binds to F8, L10, R144, C146, E229, and Y236 of the eEF2K protein and promotes its proteasomal degradation by increasing the interaction between eEF2K and the …
Smoke And Mirrors, Adara London
Smoke And Mirrors, Adara London
Master of Arts in Professional Writing Capstones
When a human trafficking ring comes to town, a grieving graduate student must choose between investigating on her own to save her sister or leaving the investigation to her impassive cop boyfriend.
A Multi-Faceted Approach To The Alzheimer’S Disease Proteome: From Human To Mouse Models, Jay M. Yarbro
A Multi-Faceted Approach To The Alzheimer’S Disease Proteome: From Human To Mouse Models, Jay M. Yarbro
Theses and Dissertations (ETD)
Amyloid pathology is the central hallmark of Alzheimer’s disease (AD) and related dementias (ADRD). We analyzed the dementia with Lewy bodies disease (DLBD) proteome, a disorder also associated with amyloid pathology, and compared to the AD proteome, identifying conserved alterations in amyloid pathology and shared components in amyloid plaques, including MDK and NTN1. We additionally evaluated major AD mouse models to determine their relevance to human disease and identify shared proteomic alterations. We observed alterations in several highly conserved matrisomal components consistently im- plicated in proteomic analyses of human amyloidosis disorders. We additionally identified several pathways influenced by amyloid-pathology that …
Matrix Gene Splicing And Emergence Of Highly Pathogenic Avian Influenza, Christopher Patton
Matrix Gene Splicing And Emergence Of Highly Pathogenic Avian Influenza, Christopher Patton
Theses and Dissertations (ETD)
Highly pathogenic avian influenza (HPAI) is a continual threat to the commercial poultry industry. In the past 40 years there have been five outbreaks of HPAI in North America. Rapid responses to these outbreaks have been crucial in preventing HPAI from becoming endemic in North America. The three worst outbreaks of HPAI in North America occurred in 1983-84, 2014-15, and 2021-23. The most recent outbreak was the worst North American HPAI outbreak in recorded history and will likely result in endemicity. Here we described the three worst recorded HPAI outbreaks in North America. The first of these outbreaks occurred in …
An Examination Of Non-Core Teacher Training In Special Education, Courtney Farber
An Examination Of Non-Core Teacher Training In Special Education, Courtney Farber
Masters Projects
Research has shown that many non-core educators such as art, music, and physical education educators may lack the training needed to properly service students with special needs in their classrooms. The undergraduate programs researched were found to only require one course about special education. This lack of training leaves educators unprepared and always wondering how to best teach students with special needs in their classrooms. The lack of educator training also means that students with special needs are not able to participate to their full ability within these classes. This project looks at the training received by educators, the different …
Biomarkers Of Objective Criteria For Subtle Cognitive Decline In Parkinson’S Disease, Mary Ellen Garcia
Biomarkers Of Objective Criteria For Subtle Cognitive Decline In Parkinson’S Disease, Mary Ellen Garcia
Electronic Theses, Projects, and Dissertations
Mild cognitive impairment in Parkinson’s disease (PD-MCI) is the continuum from normal cognitive function to dementia. Recent studies suggest that objectively defined subtle cognitive decline (Obj-SCD), which uses non-traditional “process” neuropsychological scores, may be a better pathway to earlier detection of cognitive impairment. Obj-SCD has been defined as the stage where cognition is not impaired, but biomarkers are present or cognitive impairment is minimal but not sufficient to meet MCI or dementia criteria. We examined the longitudinal trajectories of neurodegenerative markers among individuals who are classified as cognitive normal (CN), Obj-SCD, and PD-MCI. Past literature has been inconsistent about the …