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A New Technique For Solving Neutral Delay Differential Equations Based On Euler Wavelets, Mutaz Mohammad, Alexander Trounev

All Works

An effective numerical scheme based on Euler wavelets is proposed for numerically solving a class of neutral delay differential equations. The technique explores the numerical solution via Euler wavelet truncated series generated by a set of functions and matrix inversion of some collocation points. Based on the operational matrix, the neutral delay differential equations are reduced to a system of algebraic equations, which is solved through a numerical algorithm. The effectiveness and efficiency of the technique have been illustrated by several examples of neutral delay differential equations. The main advantages and key role of using the Euler wavelets in this …

Host Species And Captivity Distinguish The Microbiome Compositions Of A Diverse Zoo-Resident Non-Human Primate Population, Maya O. Wills, Robin R. Shields-Cutler, Emily Brunmeier, Madison Weissenborn, Tami Murphy, Dan Knights, Timothy J. Johnson, Jonathan B. Clayton

Department of Food Science and Technology: Faculty Publications

Vast numbers of microorganisms inhabit the mammalian gastrointestinal tract in a complex community referred to as the gut microbiome. An individual’s microbiome may be impacted by genetics, diet, and various environmental factors, and has been associated with many health states and diseases, though specific explanations are lacking. While these communities are well-studied in human populations, non-human primates (NHPs), in particular zoo-resident or captive NHPs, offer distinct advantages to increasing our understanding of factors that influence gut microbiome composition. Here, we characterize the gut microbiome composition of a phylogenetically diverse cohort of NHPs residing in the same urban zoo. We show …

Macrodosing To Microdosing With Psychedelics: Clinical, Social, And Cultural Perspectives, Ayse Ceren Kaypak, Amir Raz

Psychology Faculty Articles and Research

To date, the clinical and scientific literature has best documented the effects of classical psychedelics, such as lysergic acid diethylamide (LSD), psilocybin, and dimethyltryptamine (DMT), in typical quantities most often associated with macrodosing. More recently, however, microdosing with psychedelics has emerged as a social trend and nascent therapeutic intervention. This variation in psychedelic practice refers to repeat, intermittent ingestion of less-than-macrodose amounts that do not cause the effects associated with full-blown “trips”. Microdosing paves the road to incorporating psychedelic drugs into a daily routine while maintaining, or even improving, cognitive and mental function. Unlike macrodosing with psychedelics, the influence of …

Karakterisasi Enzim Amilase Isolat Bakteri R2m Larva Kumbang Sagu Dari Luwu Utara, Maswati Baharuddin, Nur Alfina, Amalyah Febryanti, Fitria Azis, Wulan Wahyuningsih

Chimica et Natura Acta

Karakterisasi ekstrak kasar enzim amilase isolat bakteri R2M dari larva kumbang sagu telah dilakukan. Penelitian ini bertujuan untuk mengetahui aktivitas enzim amilase pada suhu, pH, dan konsentrasi substrat optimum terhadap substrat amilum murni dan amilum dari kulit singkong. Penentuan aktivitas enzim amilase menggunakan metode asam 3,5-dinitrosalisilat (DNS) yang diukur dengan spektrofotometer visible pada panjang gelombang (λ) 540 nm. Hasil penelitian menunjukkan bahwa enzim amilase isolat bakteri R2M larva kumbang sagu yang direaksikan dengan substrat amilum optimum pada suhu 70°C, pH 4, dan konsentrasi substrat 1,25% dengan aktivitas enzim masing-masing sebesar 0,116 U/mL; 0,049 U/mL; dan 0,044 U/mL. Aktivitas enzim amilase …

Comorbidity Of Novel Crhr2 Gene Variants In Type 2 Diabetes And Depression, Mutaz Amin, Jurg Ott, Derek Gordon, Rongling Wu, Teodor T Postolache, Michael Vergare, Claudia Gragnoli

Department of Psychiatry and Human Behavior Faculty Papers

The corticotropin-releasing hormone receptor 2 (CRHR2) gene encodes CRHR2, contributing to the hypothalamic-pituitary-adrenal stress response and to hyperglycemia and insulin resistance. CRHR2-/- mice are hypersensitive to stress, and the CRHR2 locus has been linked to type 2 diabetes and depression. While CRHR2 variants confer risk for mood disorders, MDD, and type 2 diabetes, they have not been investigated in familial T2D and MDD. In 212 Italian families with type 2 diabetes and depression, we tested 17 CRHR2 single nucleotide polymorphisms (SNPs), using two-point parametric-linkage and linkage-disequilibrium (i.e., association) analysis (models: dominant-complete-penetrance-D1, dominant-incomplete-penetrance-D2, recessive-complete-penetrance-R1, recessive-incomplete-penetrance-R2). We detected novel linkage/linkage-disequilibrium/association …

Increased Extent Of Waterfowl Grazing Lengthens The Recovery Time Of A Colonizing Seagrass (Halophila Ovalis) With Implications For Seagrass Resilience, Caitlyn M. O’Dea, Paul S. Lavery, Chanelle L. Webster, Kathryn M. Mcmahon

Research outputs 2022 to 2026

Herbivore distributions and abundance are shifting because of climate change, leading to intensified grazing pressure on foundation species such as seagrasses. This, combined with rapidly increasing magnitudes of change in estuarine ecosystems, may affect seagrass resilience. While the overall resilience of seagrasses is generally well-studied, the timeframes of recovery has received comparatively little attention, particularly in temperate estuaries. We investigated how the recovery time (RT) of seagrass is affected by simulated grazing in a southwestern Australian estuary. Whilst excluding swans, we simulated different grazing intensities (25, 50, 75, and 100 % removal from 1 m2 plots) at four locations in …

Effects Of Various Solvents On Adsorption Of Organics For Porous And Nonporous Quartz Co2 Brine Systems: Implications For Co2 Geo-Storage, Muhammad Ali, Nurudeen Yekeen, Mujahid Ali, Mirhasan Hosseini, Nilanjan Pal, Alireza Keshavarz, Stefan Iglauer, Hussein Hoteit

Research outputs 2022 to 2026

The underground geo-storage of carbon dioxide (CO₂) is an essential component of the carbon capture and sequestration value chain. The success of CO₂ containment depends on the wetting state of the rock, which controls the mechanism of fluid flow and distribution. The presence of organic acids in the storage formation introduces a considerable effect on the wettability of the rock / CO₂ / brine system under various temperature and pressure conditions. Despite the previous studies on this topic, the impact of the substrate pores, the rock surface roughness, and the solvents used to prepare the organic …

Environment Protection In The South China Sea : A Study Of The Applicability In The Designation Of A Particularly Sensitive Sea Area (Pssa), Tao Yang

World Maritime University Dissertations

No abstract provided.

Legal Fundamentals And Key Issues For Establishing International Ocean Carbon Sink Organization, Qilong Liao

World Maritime University Dissertations

No abstract provided.

Research On Countermeasures To Strengthen Domestic Traffic Safety Based On Risk Control, Hui Lin

World Maritime University Dissertations

No abstract provided.

The Effects Of Covid 19-Related Social Media Hate Crime On Asian And Asian Americans' Self-Esteem, Saachi Chugh

LSU Master's Theses

The COVID-19 pandemic has changed the way people communicate, live, socialize and perhaps the way they feel about the Asian population. The United States has seen a rise in the Asian hate crimes on online and offline platforms since the beginning of the pandemic which has affected the overall well-being of the Asian population. To our knowledge, the present study is one of the first studies to address the effects of COVID 19-related online perceived racial discrimination on the self-esteem of Asians. Additional objectives were to reveal the different coping mechanisms being used by the Asian population to cope with …

In Silico And In Vitro Studies Of Taiwan Chingguan Yihau (Nricm101) On Tnf-Α/Il-1Β-Induced Human Lung Cells, Yih-Dih Cheng, Chi‑Cheng Lu, Yuan-Man Hsu, Fuu-Jen Tsai, Da-Tian Bau, Shih-Chang Tsai, Ching-Chang Cheng, Jen-Jyh Lin, Yuang-Yu Huang, Yu-Ning Juan, Yu-Jen Chiu, Sheng-Chu Kuo, Jai-Sing Yang, Lii-Tzu Wu

BioMedicine

COVID-19 pandemic has been a global outbreak of coronavirus (SARS-CoV-2 virus) since 2019. Taiwan Chingguan Yihau (NRICM101) is the first traditional Chinese medicine (TCM) classic herbal formula and is widely used for COVID-19 patients in Taiwan and more than 50 nations. This study is to investigate in silico target fishing for the components of NRICM101 and to explore whether NRICM101 inhibits cytokines-induced normal human lung cell injury in vitro. Our results showed that network prediction of NRICM101 by a high throughput target screening platform showed that NRICM101 has multiple functions that may affect cytokine regulation to prevent human lung cell …

Ethanol Leaf Extract Of Hoslundia Opposita In In Vivo Antioxidant And Hepatoprotective Activity Using An Animal Model, Fred Coolborn Akharaiyi, Odoligie Imarhiagbe, Lucky Efe Isunu, Adebayo Thomas Ajibola

BioMedicine

Introduction and aim: The liver is a useful organ that is responsible for the detoxification of harmful substances from the body. Its vital role is of importance hence it should be protected from damages in order to function normally. The management of liver diseases with orthodox medicine has been found to have side effects thus its effective management with folklore has been found better.

Materials and Methods: The leaves of H. oppisota harvested from a forest was processed and extracted with ethanol. The extract concentrations of 100 to 400 mg/ml was used to evaluate acute toxicity, biochemical analysis, …

The Evaluation Of Serum Lipid Profile And Apolipoprotein C-1 In The Iranian Patients Of Oral Squamous Cell Carcinoma, Walaa Alazzawi, Zahra Shahsavari, Hanieh Babaei, Hadis Firouzpour, Abbas Karimi, Afsaneh Goudarzi

BioMedicine

Background: The key role of apolipoprotein C-1 (ApoC-1) is reported in breast, pancreas and lung cancer. However, no information is available on potential difference of ApoC-1 between OSCC patients and healthy individuals. This work aimed to examine the serum ApoC-1 level as well as lipid profile values between OSCC patients and healthy control groups.

Material and Methods: In this study, 44 blood samples from 22 OSCC patients and 22 healthy individuals were collected to determine the values of lipid profile and ApoC-1 concentration using colorimetric method and Enzyme-Linked Immunosorbent Assay (ELISA), respectively.

Results: A significant decrease in serum lipid profile …

Lep G2548a Polymorphism Is Associated With Increased Serum Leptin And Insulin Resistance Among T2dm Malaysian Patients, Layth Ahmed Ali, Khairunadwa Jemon, Nurriza Ab Latif, Suhaili Abu Bakar, Sharifah Sakinah Syed Alwi

BioMedicine

Background: Type 2 diabetes mellitus (T2DM) is a chronic metabolic syndrome that is rapidly increasing across the world, especially in Malaysia. Leptin plays a vital role in the regulation of metabolism through its effect on peripheral tissues. G2548A polymorphism in the LEP gene promoter has been associated with insulin resistance, leptin, and type 2 diabetes mellitus across different population, but has not been inclusively reported within the Malaysian population.

Objective: Thus, our study aimed to investigate the impact of G2548A polymorphism on serum leptin levels and insulin resistance among Malaysian T2DM patients.

Methods: This case-control study involved …

Neovasculogenic Effect Of 11,12-Epoxyeicosatrienoic Acid Involves The Akt/Enos Signaling Pathways In Human Endothelial Progenitor Cells, Hung-Chang Hung, Jia-Ning Syu, Che-Yi Chao, Shu-Ming Huang, Cheng-Chieh Lin, Mei-Due Yang, Shu-Yao Tsai, Feng-Yao Tang

BioMedicine

The 11,12-epoxy-eicosatrienoic acid (11,12-EET) is formed from arachidonic acid (AA) by cytochrome P450 2J2 (CYP 2J2) epoxygenase and function as an effector in blood vessels. Human endothelial progenitor cells (hEPCs), a preceding cell source for endothelial cells (ECs), involve in the vascular tissue repairing by postnatal neovasculogenesis. However, the effect of 11, 12-EET on hEPCs and neovasculogenesis is not well known. In the current study, we examined the function of 11, 12-EET in hEPCs-mediated neovasculogenesis by using tubular formation analysis, Western Blotting assay, immunofluorescence staining, flow cytometry analysis and zymogram analysis. The results suggest that 11, 12-EET significantly induces neovasculogenesis …

Covid19 Vaccines And The Misinterpretation Of Perceived Side Effects, Raymond Palmer

BioMedicine

In the era of Covid19 and mass vaccination programs, the anti-vaccination movement across the world is currently at an all-time high. Much of this anti-vaccination sentiment could be attributed to the alleged side effects that are perpetuated across social media from anti-vaccination groups. Fear mongering and misinformation being peddled by people with no scientific training to terrorise people into staying unvaccinated is not just causing people to remain susceptible to viral outbreaks, but could also be causing more side effects seen in the vaccination process. This brief review will offer data that may demonstrate that misinformation perpetuated by the anti-vaccination …

Scaling Cellular Agriculture Production With Photolithography: A Study On Curing And Degradation, Alexis Garrett

Department of Mechanical and Materials Engineering: Dissertations, Theses, and Student Research

To meet the requirements for full production in cellular agriculture, a multi-disciplinary approach is required. New questions and understandings between different concepts, such as texture and cooking, need to be identified and how they correlate with cellular behavior and taste. This work focuses on understanding and developing photolithographic systems for scalable cellular agriculture. There were two specific research directions: 1) a traditional photolithography printing system was improved upon for mass manufacturing purposes and 2) mechanical analysis and degradation of key potential photolithographic biomaterials were tested for a food product. A novel digital rotational ultraviolet manufacturing (DRUM) process was developed, and …

Biofilms: Formation, Research Models, Potential Targets, And Methods For Prevention And Treatment, Yajuan Su, Jaime T. Yrastorza, Mitchell Matis, Jenna Cusick, Siwei Zhao, Guangshun Wang, Jingwei Xie

Department of Mechanical and Materials Engineering: Faculty Publications

Due to the continuous rise in biofilm-related infections, biofilms seriously threaten human health. The formation of biofilms makes conventional antibiotics ineffective and dampens immune clearance. Therefore, it is important to understand the mechanisms of biofilm formation and develop novel strategies to treat biofilms more effectively. This review article begins with an introduction to biofilm formation in various clinical scenarios and their corresponding therapy. Established biofilm models used in research are then summarized. The potential targets which may assist in the development of new strategies for combating biofilms are further discussed. The novel technologies developed recently for the prevention and treatment …

Evaluation Of Classical Guidance Programs During The Covid-19 Pandemic At Junior High School: Discrepancy Model, Hani Nurrofifah, Muh. Farozin, Asfarina Mutiara

Jurnal Kajian Bimbingan dan Konseling

Guidance and counseling programs are designed to improve education. These programs continue to evolve, especially the classical guidance programs that require adaptation to the current Covid-19 pandemic education system. However, due to a lack of planning, the development and implementation of the classical guidance program in state junior high schools during the Covid-19 pandemic have not been optimal. Thus, this study identifies the performance of the classical guidance program at state junior high schools during the Covid-19 pandemic, using predetermined standards. This study used program evaluation standards and criteria from the Guidelines for Performance-Based Professional School Counselor Evaluation. The guidelines …

Exploring The Association Of Physician Characteristics To Patient Requests For Genetic Testing, Vanessa B. Crowther, Sandra G. Suther, Jullet Davis Weaver, Clement K. Gwede, Matthew T. Dutton, Dongming Cui, Ivette A. López

Florida Public Health Review

Background: Cancer genomic testing improves health outcomes for individuals at risk, drives cost-efficiency, and facilitates healthcare equity; however, little is known about how physician demographic and practice characteristics influence patient requests for genetic testing. Purpose: To explore whether (and to what extent) physician demographic and practice characteristics are associated with patient requests for cancer genetic testing. Methods: A cross-sectional quantitative design survey was distributed to 1240 primary care physicians registered with the state health department who had active licenses and main practices in Florida. Primary care physicians were defined as those who practice family medicine, internal medicine, obstetrics, and gynecology. …

Occupational Health And Safety Trainees Reflect On Their Education And Future Careers During Covid-19., Jennifer Marshall Phd, Mph, Cph, Vidya Chandran Mba, Mph, Cph, Bds, Davies Toluhi Mbchb, Mph, Cph, Karen D. Liller Phd, Mph, Cph, Saloni Mehra Mph, Cph, Candace Burns Phd, Ms, Aprn, Faaohn

Florida Public Health Review

Background: The National Institute for Occupational Safety and Health (NIOSH) funded Education and Research Centers (ERCs), located at 18 universities, with the mission to train occupational safety and health (OSH) leaders. The Florida Sunshine ERC has trained hundreds of students since its inception in 1997 through seven programs that collaboratively foster interdisciplinary education and applied research and practice. The COVID-19 pandemic has presented practical challenges for educators, students, and trainees, forcing institutions to move to remote learning. The pandemic also magnifies the importance of public health and OSH.

Purpose: This evaluation elicited feedback from ERC trainees early in the …

Identifying The Research And Trends In Stem Education In Pakistan: A Systematic Literature Review, Sarfraz Aslam, Atif Saleem, Teresa J. Kennedy, Tribhuwan Kumar, Khalida Parveen, Huma Akram, Baohui Zhang

Education Faculty Publications and Presentations

Although STEM is an essential feature of 21st-century education and learning, there is a lack of awareness about it in Pakistan, especially at the K-12 and tertiary levels. Recently many initiatives have been launched across Pakistan to create more interest in STEM education. In order to assist in raising the level of STEM awareness in Pakistan, this study sought to examine the current state of research and identify recent contributions and gaps in the literature. A systematic literature review was conducted using 22 research papers from five renowned databases. Results produced limited research in this area, with the majority being …

Healthy Exosomes And Their Effects On Diabetic Cardiomyocytes, Miguel A. Garza, Genaro A. Ramírez-Correa, Maria Lourdes Garza-Rodríguez, Andres J. Medina

MEDI 9331 Scholarly Activities Clinical Years

Extracellular Vesicles, and more specifically, exosomes, are essential for effective cell-to-cell communication in a wide variety of tissues. In the last couple of decades, these nanovesicles have been proven to be active participants and regulators in many disease processes; therefore, their therapeutic effects have been widely studied and proven in various cardiovascular diseases both, in vitro and in vivo. Thus, this study aims at assessing the effects of running healthy mice exosomes on cardiomyocyte and cardiac tissue samples obtained from diabetic mice. Here, we successfully extract exosomes from mice plasma and detect their presence through the use of anti-CD9 and …

Ncoa4 Regulates Iron Recycling And Responds To Hepcidin Activity And Lipopolysaccharide In Macrophages, Cole A. Guggisberg, Juyoung Kim, Jaekwon Lee, Xiaoli Chen, Moon-Suhn Ryu

Department of Biochemistry: Faculty Publications

Macrophages, via erythrophagocytosis, recycle iron from effete erythrocytes to newly developing red blood cells. Conversion of potentially cytotoxic levels of iron from its heme into nonheme form during iron recycling is safely accomplished via coordinated regulations of cellular iron transport and homeostasis. Herein, we demonstrate the roles and regulation of NCOA4 (nuclear receptor coactivator 4)-mediated ferritinophagy in macrophages after erythrophagocytosis using the mouse macrophage cell line J774 cells. Ferritin in J774 cells increased with the rise of nonheme iron by erythrocyte ingestion and declined when total cellular iron contents subsequently decreased. NCOA4, a selective autophagic cargo receptor for ferritin, was …

A Novel Electrochemical Sensor Based On Au/Rgo/Feooh For One-Step Detection Of Nitrite, Da-Juan Luo, Bing-Qian Liu, Meng-Yan Qin, Rong Gao, Li-Xia Su, Yong-Huan Su

Journal of Electrochemistry

Nitrite, a widespread raw material, is harmful to human health for long-term consumption. At present, the detection methods of nitrite mainly include chemical analysis, fluorescence, ultraviolet spectrophotometry and chromatography. These methods have ideal sensitivity and selectivity, but also have some characteristics: cumbersome operation, expensive equipment and professional personnel. Therefore, the development of a simple and sensitive nitrite assay is of great significance. In this paper, the Au/rGO/FeOOH composite materials, which revealed good synergistic catalytic performance among the three elements in the composite, were prepared by simple hydrothermal method and reduction method for the first time with large specific surface area …

Immobilization Of A Bienzymatic System Via Crosslinking To A Metal-Organic Framework, Raneem Ahmad, Sydnie Rizaldo, Sarah E. Shaner, Daniel S. Kissel, Kari Stone

Chemistry Department Faculty Articles

A leading biotechnological advancement in the field of biocatalysis is the immobilization of enzymes on solid supports to create more stable and recyclable systems. Metal-organic frameworks (MOFs) are porous materials that have been explored as solid supports for enzyme immobilization. Composed of organic linkers and inorganic nodes, MOFs feature empty void space with large surface areas and have the ability to be modified post-synthesis. Our target enzyme system for immobilization is glucose oxidase (GOx) and chloroperoxidase (CPO). Glucose oxidase catalyzes the oxidation of glucose and is used for many applications in biosensing, biofuel cells, and food production. Chloroperoxidase is a …

Family | Home | School, Latoya Baldwin Clark

Northwestern University Law Review

The state grants residents who live within a school district’s border an ownership interest in that district’s schools. This interest includes the power to exclude nonresidents. To attend school in a school district, a child must prove that she lives at an in-district address and is a bona fide resident. But in highly-sought-after districts and schools, establishing a child’s bona fide residence may be highly contested.

In this Essay, I show that education law, policies, and practices fail to recognize a child’s residence when the child’s family and living situation do not comport with a particular ideal of family life. …

Streaming Property, Lee Anne Fennell

Northwestern University Law Review

People acquire property rights in objects and real estate in order to capture the stream of services that these assets can provide over time. The thing or parcel itself is merely a delivery mechanism, a way of packaging and protecting rights to that value stream. And, significantly, these assets cannot stream services to anyone without a set of facilitating conditions and complementary goods, such as public infrastructure, that do not lie within the asset owner’s individual control. This Essay argues that we can gain fresh traction on inequality by recasting property as service streams rather than as owned things. Doing …

Apoptosis Detection In Retinal Ganglion Cells Using Quantitative Changes In Multichannel Fluorescence Colocalization, Xudong Qiu, Seth T Gammon, James R Johnson, Federica Pisaneschi, Steven W Millward, Edward M Barnett, David Piwnica-Worms

2020-Current year OA Pubs

KcapTR488 is a dual-fluorophore peptide sensor for the real-time reporting of programmed cell death by fluorescence imaging. KcapTR488 contains a nuclear localization sequence (NLS) conjugated with Texas Red, a caspase-cleavable sequence (DEVD), and a C-terminus conjugated to Alexa Fluor 488 (AF488). The synthesis and preliminary evaluation in cellulo of KcapTR488 for monitoring cell death by fluorescence imaging has been previously reported, but its utility in vivo has yet to be tested or validated. Herein, in vitro solution experiments verified the intramolecular fluorescence resonance energy transfer (FRET) between the two fluorophores and enabled a quantitative analysis of enzyme rates and selectivity. …