Digital Commons Network^™

The 2026 Mda Award Winners: Recognizing Outstanding Service, David Foe

The Journal of the Michigan Dental Association

This article lists the recipients of the 2026 MDA awards, highlighting their contributions to the dental profession and public health. Notable winners include Dr. Christopher Smiley, recipient of the Meritorious Award for a lifetime of achievement in dental journalism and leadership, and Dr. Charles Burling, honored as Dentist Citizen of the Year for his community service. The feature also recognizes educators, legislative advocates, and volunteers in the Donated Dental Services (DDS) program who provide care to vulnerable populations.

Fresh Phytoplankton Bloom Growth In The Fall And Its Control On Ocean Heating In The Pacific Arctic Region, Clare B. Gaffey, K E. Frey, Bonnie Light, Lee W. Cooper, Jacqueline M. Grebmeier

Geography

Delayed sea ice freeze-up and decreased sea ice extent in the Pacific Arctic region have altered light availability in marine waters, extending the ice-free season and increasing opportunities for photosynthetic activity and energy exchanges. This study investigates phytoplankton bloom progression during the fall using chlorophyll pigments and examines the impact phytoplankton have on heat distribution within the water column. Measurements of chlorophyll-a concentrations and its associated degradation product pheophytin were made in conjunction with optical measurements of light transmittance within the upper water column during the Synoptic Arctic Survey cruise in the Central Arctic Ocean and northeast Chukchi Sea in …

Considerations When Designing In Vivo Protocols For Conducting Biomechanical Research Of The Shoulder Joint In Hockey Athletes, Kylie Giesler

Honors Program Theses

While the numbers and details of hockey-related injuries are variable across sources due to variations in sample age, sex, location, and confidentiality of many large hockey leagues, a 2023 narrative review study identified more than 100,000 upper extremity injuries documented in research since 2000. Nearly half of those injuries were to the shoulder with common injuries being acromioclavicular joint sprains, shoulder instability and dislocations, labral and rotator cuff tears, and clavicle fractures. In respect to the National Hockey League (NHL), the highest level of play in ice hockey, 12% of all injuries are to the shoulder, second only to head …

Diacylglycerol Kinase Eta As A Novel Target In Nras Mutant Melanoma, Haley P. Wilson, Casey D. Stefanski, Signe Caksa, Glenn L. Mersky, Scott D. Varney, Jelan I. Haj, Dan A. Erkes, Timothy J. Purwin, Vivian Chua, Andrew E. Aplin

Department of Pharmacology, Physiology, and Cancer Biology Faculty Papers

NRAS mutations occur in 10%-30% of cutaneous melanomas and are associated with high tumor mutational burden. Mutant NRAS signaling drives aberrant cell growth and proliferation, in part, through activation of the RAF-MEK-ERK1/2 kinase pathway; however, targeted therapies to this pathway have limited effectiveness in patients with NRAS mutant melanoma. The role of other targetable signaling pathways in NRAS mutant melanoma is poorly characterized. Here, we demonstrated that one isoform of diacylglycerol kinase, diacylglycerol kinase eta (DGKη), a lipid signaling regulator, was highly expressed in NRAS mutant melanoma patient samples. Knockdown of DGKH in NRAS mutant melanoma cell lines resulted in …

Illinois State University, One Hundred And Sixty-Seventh Annual Commencement, May 2026, Illinois State Universtiy

Commencement Programs

Illinois State University

One Hundred and Sixty-Seventh Annual Commencement

May 2026

Are College Students Thinking Twice About Having Kids? How Political Factors May Affect The Future Birth Rate In The United States, Gloria Flores

Theses and Dissertations

The trend of the birth rate decline is an important phenomenon which has attracted scholarly attention in the United States. Prior research has explored factors such as income, education, and personal preferences. However, there is minimal research on how the political environment affects people’s family planning decisions. That is, in what ways might perceptions of modern politics affect whether people decide to have children? The limited amounts of research in other countries focusing on political efficacy and its effects on people’s decision to have children have found that people are highly sensible about their political environment when it comes to …

2024 Annual Operations And Maintenance Report 2024 Bres Annual Summary Report For Work Completed In Quadrant 4, Butte-Silver Bow Department Of Reclamation And Environmental Services

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Mif-Cd74 Signaling Drives Immune Modulation In Medulloblastoma, Benjamin Draper, Zhen You, Dean Thompson, Xu Guo, Alaide Morcavallo, Diego Chillon Pino, Carlos Lorenzo Gido Nery, Sumana Shrestha, Chantelle E Bowers, Courtney Himsworth, Alberto Delaidelli, Bethany Remeniuk, Sonia Morlando, Brandon Wade, Freya Gordon, Yara Sanchez-Corrales, Bei Hopkins, Natalie Monteiro, Darren Locke, Miao Liu, Jacob Torrejon Diaz, Kevin Greenslade, Barbara Martins Da Costa, Karen Barker, Colin Kwok, Olumide Ogunbiyi, Anya Fletcher, Stacey Richardson, Carlos Custodia, Rafael Roque, Thomas Jackson, Regan Barfoot, Sergi Castellano, Rebecca M Hill, Olivier Saulnier, Thomas S Jacques, Michael D Taylor, Claudia C Faria, Olivier Ayrault, Poul H Sorensen, John Anderson, Louis Chesler, L Frank Huang, Steven C Clifford, Laura K Donovan

Faculty, Staff and Students Publications

Background: Relapsed medulloblastoma remains a significant therapeutic challenge as it is near universally fatal. The tumor microenvironment of medulloblastoma plays a critical role in tumor progression, influencing tumor growth, immune evasion, and therapeutic resistance. We hypothesized that defining tumor-immune interactions in diagnostic and relapsed medulloblastoma may uncover mechanisms of immune evasion and identify novel therapeutic targets.

Methods: We analyzed paired primary and recurrent RNA-sequencing data from 140 medulloblastoma patients to profile immune cell composition and validate spatial relationships within the TME. To identify key tumor-immune interactions, we developed a novel algorithm to detect receptor-ligand pairs using single-cell RNA-sequencing data. These …

Noncanonical Clock Regulators Control Stress Responses In Digestive Diseases, Dishu Zhou, Roberto E López-Valiente, Samer G Mattar, Dongyin Guan

Faculty, Staff and Students Publications

The digestive system is essential for nutrient absorption, processing, and waste elimination. The expression of many genes and physiological processes within this system exhibits a 24-h rhythmicity. However, modern lifestyle factors, such as jet lag, shift work, and irregular eating patterns, significantly disrupt these rhythms, triggering various stress responses and contributing to numerous digestive disorders. Here, we focus on emerging studies on noncanonical clock regulators involved in stress responses, integrate these novel findings into the established model of the core circadian clock, and highlight recent advances in the development of novel therapeutics targeting these 24-h regulators. In addition, we discuss …

The Relationship Between Sports Related Head Injuries, Mental Health And Academic Performance In University Student-Athletes, Odyssey Keller

Electronic Theses and Dissertations

Student athletes face many challenges when it comes to participating in team sports, one of the most notable being sport-related head injuries. Concussions are a growing concern since they have the potential to impact mental health and academic performance long-term. While many athletes report recovery within weeks, some continue to struggle with impairments in their psychological functioning and overall mental well-being that interferes with academic performance over time. Many of the standardized protocols in place for concussion management vary across institutions. This study aimed to address gaps in the existing literature by assessing concussion history, mental health and academic challenges …

Analysis Of Potential Alkali Reactivity Of Aggregates In Arkansas, Brigita Dowling

Civil Engineering Undergraduate Honors Theses

Alkali Silica Reaction (ASR) is a deleterious chemical reaction in concrete that leads to the deterioration of concrete structures. This reaction occurs between minerals present in aggregates and alkalis in the cement, and produces a gel-like substance called alkali silicate gel. Gradually, these gels absorb water from the environment and expand, leading to internal stresses in the concrete. This damage results in expansion, cracking, and deformation, reducing the strength and durability of the concrete significantly. While this damage appears minor initially, eventually they can lead to the need for costly repairs or replacement of the concrete. ASR has been observed …

Conventional Vs. Regenerative Apple Orchard Management In Michigan, Anthony Poynter

Masters Theses

This study compares the variables and outcomes of a conventional apple orchard and a regenerative apple orchard production system in Kent County, Michigan. The premise is that conventional agriculture relies on high-input systems characterized by synthetic fertilizers, pesticides, herbicides, and fungicides, while regenerative agriculture focuses on long-term soil health, biodiversity, and ecological processes. These differences are important as soil degradation, nutrient loss, and environmental impacts are becoming too significant to ignore. Most research on alternative ways to farm, such as regenerative practices, is focused on annual crops, while perennial orchard systems, especially in the Great Lakes region, have gained limited …

Changing Dynamics Of Microbial Communities At A Hydrocarbon Contaminated Site And Methanogenic Interactions With Iron Minerals, Jakob Sell

Masters Theses

Microbial life is not only ubiquitous but also plays a critical role in the geochemical makeup of our planet. While researchers have long studied easily culturable aerobic microbes, the influence of anaerobic life on soils and mineral cycling is less understood. Notably, knowledge about interactions between anaerobic microbes and inorganic elements such as iron has progressed with the discovery that magnetite influences how anaerobic archaea carry out methanogenesis. To better understand anaerobic bacterial metabolisms and how they interact with minerals and subsurface hydrocarbons, we extracted 16S rRNA genes from two adjacent subsurface petroleum plumes, sequenced the DNA, and analyzed it …

May 2026 News Releases, University Of Montana--Missoula. Office Of University Relations

University of Montana News Releases, 1928, 1956-present

No abstract provided.

Beyond Duality: The Doppelganger And The Multiplicity Of Identity In Oscar Wilde's The Picture Of Dorian Gray, Alyssa Roberts

Theses, Dissertations and Culminating Projects

This paper argues that Oscar Wilde uses The Picture of Dorian Gray to transform the Gothic doppelganger from a symbol of moral duality into a site of multiplicity that exposes the instability of identity. Earlier iterations of the double–ranging from mythic traditions to nineteenth-century texts—such as The Strange Case of Dr. Jekyll and Mr. Hyde—tend to structure the self through binary opposition. Wilde, however, reconfigures the double as an accumulative and dynamic process. This paper analyzes how Wilde disrupts the rigidity of Victorian binaries and society’s investment in duality through the portrait’s accumulation of the consequences of Dorian’s actions as …

Artificial Intelligence In Dental Education: A Literature Review Of Global Adoption, Pedagogical Outcomes, And Ethical Implications, Betti Shahin, Jeremiah D. Ghodsi, Toleen Mazloum, Denise Hale

Journal of Educational Leadership in Action

Background: Artificial intelligence (AI) is revolutionizing many fields by enabling machines to accomplish tasks that previously required human intelligence, such as learning, decision-making, and problem-solving. In dentistry, AI is increasingly applied to diagnostics, treatment planning, and clinical training. Its integration enhances educational experiences for students while supporting more accurate and efficient patient care.

Objective: This review synthesizes recent research on AI in dental education, highlighting global adoption trends and key pedagogical, ethical, and practical considerations.

Conclusion: AI has significant potential to enhance dental education through innovative teaching, clinical training, and data-driven decision-making. Effective integration depends on institutional …

Degradation And Metabolic Analysis Of Synthesized Quorum-Sensing Signals By The Model Eukaryote Chlamydomonas Reinhardtii, Adam Josef Bach

Theses and Dissertations

Bacterial organisms can “talk” with one another on a colony-wide scale using a communication system known as quorum-sensing (QS) via chemical signals. These signals are produced at a basal rate throughout the life of the bacteria and are classified as autoinducers, which diffuse across the cell membrane. Once the critical concentration is reached, they begin to diffuse back into the cell and initiate a phenotypic change. As these signals exist outside the membrane of their producer, they are also accessible to other organisms. It has already been noted that some plant species uptake these compounds through their roots and break …

Ligand-Based Pharmacophore Modeling And Structure-Based Virtual Screening For Identifying Potential Therapeutic Agents Targeting The Sars-Cov-2 Spike Protein-Ace2 Receptor Interaction, Timoteo Delgado-Maldonado, Gilberto Vargas-Salas, Debasish Bandyopadhyay, Adriana Moreno-Rodriguez, Eyra Ortiz-Pérez, Gildardo Rivera-Sanchez

School of Integrative Biological & Chemical Sciences Faculty Publications

Coronavirus disease (COVID-19) remains a global health concern due to its high mortality and morbidity. In this study, we combined ligand-based pharmacophore modeling (LBPM) with structure-based virtual screening (SBVS) to identify novel inhibitors targeting the SARS-CoV-2 spike protein. Ligands from the MolPort database were screened via docking and molecular dynamics simulations at the receptor-binding domain (RBD). Four compounds showed promising docking scores (-8.7 to -6.4 kcal/mol) and dynamic stability (root mean square deviation < 5 Å). In vitro assays confirmed that compounds C3 (IC50 = 0.03 µM) and C4 (IC50 = 10.4 µM) effectively inhibited spike-ACE2 binding with low cytotoxicity (CC50 > 100 µM). These findings show the efficacy of the LBPM technique and highlight 1H-pyrazol-5-ol derivatives as potential building blocks for developing new antiviral agents against SARS-CoV-2.

Metabolic And Replicative Constraints On Pathogen Virulence: Isoleucine Catabolism In Shigella And Comparative Tanapoxvirus Replication In Cell Cultures, Benecia Angelica

Masters Theses

Pathogens survive by balancing metabolic demands with environmental challenges that shape their virulence and adaptability. Shigella flexneri, a highly infectious human pathogen responsible for severe diarrheal disease worldwide, utilizes branched-chain amino acid (BCAA) metabolism to withstand stress conditions encountered within the host environment. In this study, we explored the Shigella isoleucine catabolism pathway by knocking out four genes in the S. flexneri isoleucine catabolic pathway (ilvE, fadA, fadD, and acnB) and examining their metabolism and virulence. We found that the ilvE and acnB mutants displayed reduced metabolic activity and smaller plaque size, while the fadD mutant showed decreased invasion. In …

Ecological Responses To Living Shoreline Restoration, Aaron S. Bland

Graduate Theses and Dissertations (2019 - present)

Coastal built communities and natural coastal ecosystems face similar and interrelated hazards: shoreline sediment erosion, shoreline retreat, and worsening storms, each of which is exacerbated by relative sea level rise. Living shorelines are coastal defense projects that incorporate natural habitats to provide more sustainable shoreline defense and improve the coastal ecosystem. Living shorelines have been widely adopted, but their performance has been highly variable, and the mechanisms of project success and failure are unclear. The overarching goal of this dissertation was to better understand the ecosystem responses to coastal restoration, focusing on the primary habitats of coastal salt marsh and …

The Southwest Black Artists Collective: Afro-Modern Ecology, Kinship, And Collectivity In The Desert Southwest, Bradley L. Petty

Art History Theses and Dissertations

This thesis examines the Southwest Black Artists Collective (SBAC) as a site of

Afro-diasporic kinship, artistic production, and spatial intervention within the Desert

Southwest. Operating within a region where Black populations are comparatively small

and institutional support is diffuse, SBAC emerges as both a response to and a

reconfiguration of the regional artistic landscape. The Collective constructs an affirming

community through shared artistic practice, exhibitions, and the maintenance of The

Projects/Space in Tucson, Arizona, where public engagement and private creative

exchange coexist.

Drawing on theories of human ecology, this study expands existing frameworks

by introducing the concept of Afro-modern ecology, …

Parkinson’S Disease And Its Treatments: An Overview, Nathaniel Cook

Senior Honors Theses

Parkinson’s disease (PD) is a neurodegenerative disease closely associated with the accumulation of α-synuclein in neurons, and inhibition in the release of dopamine, a key neurotransmitter of the nervous system. Disruption in dopamine signaling can cause cognitive and motor dysfunctions, with tremor, bradykinesia, and rigidity being the most observable effects. There is no permanent treatment for PD, constituting the need for further research to improve current pharmaceutical approaches and possibly develop a cure. Main areas of research include improving medication via delivery methods, genetic mutation using CRISPR, and adaptive deep-brain stimulation. Recent developments and applications in these areas will be …

Sepsis As An Immune Continuum: Cytokine Storm To Lymphopenia And Pics, Chelsey King

Senior Honors Theses

Sepsis is a leading cause of morbidity and mortality worldwide, driven by a dynamic immune continuum that progresses from early hyperinflammation to profound immunosuppression. This review examines the three overlapping phases of sepsis: the inflammation-mediated cytokine storm driven by dysregulated PRR activation, NF-κB signaling, and NETosis; apoptosis-driven lymphopenia involving caspase-mediated lymphocyte death, dendritic cell dysfunction, and metabolic exhaustion; and prolonged immunoparalysis culminating in persistent inflammation, immunosuppression, and catabolism syndrome (PICS). Key mechanisms linking these phases, including the co-existence of hyper- and hypo-inflammatory states, are synthesized alongside relevant clinical biomarkers such as IL-6, HLA-DR, and single-cell immune profiles. This review highlights …

Associations Of Trait And Ability Emotional Intelligence With Heart Rate Variability And Emotional Reactivity In Undergraduate Students, Miriam Bowser

Senior Honors Theses

Ability emotional intelligence (EI) and trait EI have been previously associated with heart rate variability (HRV), suggesting adaptive autonomic regulation. Emotional reactivity (ER) has also been correlated with EI, possibly because individuals with higher EI are more sensitive to emotional information. The current study used a cross-sectional design (N = 71) to examine trait and ability EI, self-reported ER, and HRV. No relationship was found between trait and ability EI, suggesting distinct underlying constructs. EI was not associated with HRV. Trait EI was positively associated with positive valence (r = .34, p = .004) and ability EI with …

Lyapunov-Krasovskii Based Approach To Time-Delay Systems: Computational Efficiency And Feedback Control, Huan Phan

Dissertations

Time-delay systems arise naturally in many engineering applications due to sensing,actuation, communication, and computation delays. The presence of delays has a significant influence on system performance both positively and negatively. Although Lyapunov--Krasovskii functional (LKF) methods provide a systematic framework for stability analysis and controller synthesis, their implementation often suffers from high computational complexity, particularly for large-scale systems and systems involving multiple feedback channels. This dissertation addresses both computational efficiency and feedback control for linear time-delay systems.The first part of this dissertation develops a decomposition-based approach to reduce the computationalburden of stability analysis. By exploiting structured invariant subspaces associated with the …

Intelligent Surveillance For Weapon Threat Detection: Transformer-Based Detection And Segmentation Using Thermal And Rgb Imagery, Akhila Kambhatla

Dissertations

Proactive public-safety surveillance requires deep learning systems that can detect and segment weapons reliably under real-world conditions. This research develops and evaluates a progressive, multi-phase pipeline that moves (i) from RGB object detection to pixel-level semantic segmentation and (ii) from visible-spectrum cameras to thermal imagery to improve robustness under low-light, clutter, and occlusion. Early phases establish strong detection baselines using one-stage and two-stage detectors (YOLOv5 and Faster R-CNN) for multi-class weapon localization, followed by practical optimization through pruning and ensembling to reduce false positives and computational overhead while maintaining real-time feasibility. Building on the limitations of bounding-box localization, the methodology …

The Phylogenetic And Biogeographic History Of Cranes (Gruidae), Phillip Conrad Williams

Dissertations

Cranes (Gruidae) are a globally distributed clade of large, wetland-associated birds. Prior phylogenetic analyses have shown there to be two major subfamilies, Balearicinae and Gruinae, and five consistently recovered clades within Gruinae. However, the relationships among those five clades has remained contentious. In addition, little has been done to reconstruct the biogeographic history of cranes. To that end, I first inferred phylogeny using a large, nuclear dataset sampled from all 15 extant crane species and two outgroup species. The phylogeny mostly agreed with previous analysis using whole mitochondrial genomes but differed in that the Anthropoides species group formed a sister …

2nd Place Research Paper: Shaping The Ape: Storytelling, Cultural Reflection, And Boundary Negotiation In Human-Ape Zoo Encounters, Abigail Bond Halling

Kevin and Tam Ross Undergraduate Research Prize

The typical Western zoo functions as a unique environment in which animals are frequently positioned as subjects of education and entertainment through the medium of storytelling. In this sense, the zoological institution can also be read as an extension of popular Western constructions surrounding nonhuman animals, particularly those who are symbolically charged characters in our collective imaginary– the great apes. Given the morphological, behavioral, and psychological similarities between humans and other great apes (chimpanzees, gorillas, and orangutans), nonhuman great ape enclosures at the Western zoo become spaces where humans are most radically confronted with navigating the boundaries of the “human-animal …

Analysis Of Collective Behavior In Living And Nonliving Systems, Kaitlyn Cohan

Theses, Dissertations and Culminating Projects

This thesis aims at understanding the phenomenon of of self-organization in complex dissipative systems, living and nonliving. Dissipative systems are characterized by their search for energy, interactions with their surroundings and the production of entropy, all of which result in the creation of stable structures or patterns, which persist as long as the initial environmental conditions are maintained. The two specific models that we chose to study here are (a) Futbol (or Soccer) and (b) a chemical system involving free-floating menthol crystals floating on a fluid surface to represent nonliving systems. Using experiments and mathematical models, we will try to …

The Effects Of Dietary Interventions On Gut Microbial Balance In Healthy Adults: An Integrative Review, Miranda Demars

Senior Honors Theses

The goal of this review is to answer the question: What dietary changes are most effective in restoring gut dysbiosis in healthy adults? The gut microbiome (GM), a community of microorganisms that colonizes in the gastrointestinal (GI) tract, can become imbalanced, a condition known as dysbiosis, which is associated with an increased risk of dysbiosis-induced disease. Dysbiosis-induced diseases include GI disorders such as irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD), neurological disorders such as Alzheimer’s disease (AD) and Parkinson’s disease (PD), and metabolic disorders such as diabetes and obesity (Shen et al., 2025). Pharmacologic interventions are often not …