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2022

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Non-Criminal Behavior: Why Idaho’S Domestic Violence Laws Are Inaccurate And Inefficient, Madison E. Basterrechea Nov 2022

Non-Criminal Behavior: Why Idaho’S Domestic Violence Laws Are Inaccurate And Inefficient, Madison E. Basterrechea

Idaho Law Review

No abstract provided.


An Evening With Representative Christina Haswood, Christina Haswood Nov 2022

An Evening With Representative Christina Haswood, Christina Haswood

Student Life Events & Recordings

As part of Native American Heritage Month, join the Pacific community in welcoming Representative Christina Haswood. She'll share her insights as a young indigenous woman and as a member of the Kansas State Legislature.

Christina Haswood has a public health background and is a lifelong district resident of District 10, which she represents in the Kansas House of Representatives. At age 28, Christina is amongst the younger members of the Kansas Legislature and is one of three Native Americans elected into the 2021-2022 Legislative session.

Christina’s parents moved to Lawrence from the Navajo reservation in Arizona in pursuit of a …


The Impact Of Academic Advisor Behaviors On Persistence Of Pregnant And Single Mothers At 4-Year Nontraditional Universities: A Mixed Methods Study, Kristina King Nov 2022

The Impact Of Academic Advisor Behaviors On Persistence Of Pregnant And Single Mothers At 4-Year Nontraditional Universities: A Mixed Methods Study, Kristina King

Dissertations

Purpose: The purpose of this sequential exploratory mixed methods study was to identify and describe academic advisor behaviors that had the greatest impact on persistence perceived through the lens of students who were both pregnant and single mothers while enrolled in an undergraduate degree program at a 4-year nontraditional university. A secondary purpose of this study was to identify factors that pregnant and single mothers perceived to have impacted their persistence.

Methodology: The qualitative phase of this study consisted of one-on-one interviews to gain a deeper understanding of the lived experiences of single mothers who recently graduated from a 4-year …


School Leadership That Cultivates Collective Efficacy: Emerging Insights 2022, Kerry Elliott, Hilary Hollingsworth, Aiden Thornton, Liz Gillies, Katherine Henderson Nov 2022

School Leadership That Cultivates Collective Efficacy: Emerging Insights 2022, Kerry Elliott, Hilary Hollingsworth, Aiden Thornton, Liz Gillies, Katherine Henderson

Educational leadership

The work of the Menzies School Leadership Incubator suggests we need a new approach to leadership that supports school leaders to better manage transformational change and deepen collaborative capacity necessary to cultivate collective efficacy to improve student learning outcomes. This paper provides a description of the work of the Menzies School Leadership Incubator (“the Incubator’) and insights generated so far. The Incubator has identified five leadership domains which underpin the leadership of Collective Efficacy; Understanding Collective Efficacy Systems; Leadership Change; Leadership Team, and Leadership Collaborative Capacity.


Small-Molecule Protac Mediates Targeted Protein Degradation To Treat Stat3-Dependent Epithelial Cancer, Jinmei Jin, Yaping Wu, Zeng Zhao, Ye Wu Nov 2022

Small-Molecule Protac Mediates Targeted Protein Degradation To Treat Stat3-Dependent Epithelial Cancer, Jinmei Jin, Yaping Wu, Zeng Zhao, Ye Wu

Faculty and Student Publications

The aberrant activation of STAT3 is associated with the etiology and progression in a variety of malignant epithelial-derived tumors, including head and neck squamous cell carcinoma (HNSCC) and colorectal cancer (CRC). Due to the lack of an enzymatic catalytic site or a ligand-binding pocket, there are no small-molecule inhibitors directly targeting STAT3 that have been approved for clinical translation. Emerging proteolysis targeting chimeric (PROTAC) technology-based approach represents a potential strategy to overcome the limitations of conventional inhibitors and inhibit activation of STAT3 and downstream genes. In this study, the heterobifunctional small-molecule-based PROTACs are successfully prepared from toosendanin (TSN), with 1 …


2022-11-22_Michiganoverview_Covidcounts, Michigan Department Of Health & Human Services Nov 2022

2022-11-22_Michiganoverview_Covidcounts, Michigan Department Of Health & Human Services

Michigan COVID-19 Confirmed Cases by Date of Onset Data

Data was downloaded as an Excel spreadsheet which appeared in the Public Use Datasets section under the Cumulative Data link of Michigan's Coronavirus webpage, under the url https://www.michigan.gov/coronavirus/stats.

Cases are aggregated by the date of onset of COVID-19 symptoms, if known, otherwise by laboratory specimen date if known, otherwise by case referral date. Deaths are aggregated by the date of death if known, otherwise by the last date of a change to the case status.


'It’S Just Filth:’ Banned Books And The Project Of Queer Erasure, Caitlin O'Loughlin, Taylor Schmidt, Jocelyn Glazier Nov 2022

'It’S Just Filth:’ Banned Books And The Project Of Queer Erasure, Caitlin O'Loughlin, Taylor Schmidt, Jocelyn Glazier

Northwest Journal of Teacher Education

This paper seeks to explore the connection between the banning of queer books, the creation of discourses of controversy, and the erasure of queer knowledges and peoples from schools. Using a queer theory-informed approach to critical discourse analysis, we ask how these proposed bans seek to erase queer peoples, how this impacts teachers, and what teacher preparation programs can do to counter these acts of destruction.


Wanderer, Nancy, Mary Wallace Nov 2022

Wanderer, Nancy, Mary Wallace

Querying the Past: LGBTQ Maine Oral History Project Collection

Nancy Wanderer is a professor at the University of Maine School of Law and was also the first Director of the Legal Writing Program at Maine Law. She received a B.A from Wellesley College, and M.A. from George Washington University, and a J.D. from University of Maine School of Law. Nancy Wanderer has dedicated her life to women’s rights and protecting and fighting for the rights of other minorities as well. Since growing up in New Kensington, Pennsylvania, Wanderer has always been drawn to education and Academia.

She was married to her ex-husband during her Junior year at Wellesley in …


Sea Level Rise Vulnerability Assessment For State Wildlife Areas Surrounding Humboldt Bay, Northern California, Robert M. Sullivan, Aldaron Laird, Brian Powell, Jeffrey K. Anderson Nov 2022

Sea Level Rise Vulnerability Assessment For State Wildlife Areas Surrounding Humboldt Bay, Northern California, Robert M. Sullivan, Aldaron Laird, Brian Powell, Jeffrey K. Anderson

Local Reports and Publications

Humboldt Bay has the highest rate of sea level rise (SLR) in California (47.2 cm/century). Due to compaction and tectonic subsidence, former tidelands and pastures behind dikes surrounding Humboldt Bay are lower in elevation than bay waters at high tide. Adaptation to future climate change and SLR requires that resource managers understand vulnerability and risk to each wildlife area at a local level, because adaptation to SLR is a risk-based management strategy against an uncertain future requiring site-specific solutions. We conducted a vulnerability assessment of the shoreline of three State wildlife areas surrounding Humboldt Bay: Elk River (ERWA), Fay Slough …


Spartan Daily, November 22, 2022, San Jose State University, School Of Journalism And Mass Communications Nov 2022

Spartan Daily, November 22, 2022, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2022

Volume 159, Issue 39


Disruption To Ems Service During Flood Scenarios In Western North Carolina, Julia Cardwell Nov 2022

Disruption To Ems Service During Flood Scenarios In Western North Carolina, Julia Cardwell

Journal of Rural Social Sciences

Given that the intensity and frequency of flood events will increase under climate change scenarios, the ability to model potential impacts, such as those to healthcare access, will become increasingly important. This study analyzes EMS response time under both a historical (Tropical Storm Fred in August 2021) and a modeled flood event (FEMA’s 100-yr floodplain) in western North Carolina, a predominantly rural area. The results indicate that network disruption during flood events is a concern in the study area, and while the historical event produced moderate disruption, the 100-yr event produced major disruptions throughout the study area. This research emphasizes …


2022-11-22_Michiganoverview_Isdreporting, Michigan Department Of Health & Human Services Nov 2022

2022-11-22_Michiganoverview_Isdreporting, Michigan Department Of Health & Human Services

Michigan COVID-19 Outbreak Reports

The K-12 Aged ISD Reporting page was obtained from Michigan's COVID-19 data page: https://www.michigan.gov/coronavirus/stats/k-to-12-aged-isd-reporting.

This report is created from data reported by the Michigan Disease Surveillance System (MDSS) the Michigan Department of Health and Human Services' web-based communicable disease reporting system. Data is updated every week.

The purpose of the dashboard is to report the 7 day average of COVID-19 cases in Michigan school students aged 5 through 18 at the intermediate school district and school district levels, as well as display trends over time to better illustrate the changing nature of the COVID-19 pandemic. Cases are attributed to …


Commentary: Facial Aesthetic Dermatological Procedures And Photoprotection In Chinese Populations, Wei Liu, Jean Krutmann, Yan Tian, Corinne Granger, Jaime Piquero-Casals, Carles Trullàs, Thierry Passeron, Henry W. Lim, Wei Lai Nov 2022

Commentary: Facial Aesthetic Dermatological Procedures And Photoprotection In Chinese Populations, Wei Liu, Jean Krutmann, Yan Tian, Corinne Granger, Jaime Piquero-Casals, Carles Trullàs, Thierry Passeron, Henry W. Lim, Wei Lai

Dermatology Articles

The medical literature on aesthetic dermatology has primarily focused on a light-skinned patient population, yet patients of darker skin types have different needs and priorities. In Chinese individuals, key concerns include altered pigmentation, which is perceived to age the individual, and also relates to the Chinese cultural standard of beauty of fair skin; many seek aesthetic treatment for this. Non-invasive cosmetic procedures such as lasers and injections are also gaining in popularity in the Chinese market, but this population is prone to hyperpigmentation as an adverse effect of such procedures. Considered and tailored approaches, both to primary concerns of photoaging …


Myc Regulates A Pan-Cancer Network Of Co-Expressed Oncogenic Splicing Factors., Laura M Urbanski, Mattia Brugiolo, Sunghee Park, Brittany Lynn Angarola, Nathan Leclair, Marina Yurieva, Phil Palmer, Sangram Keshari Sahu, Olga Anczuków Nov 2022

Myc Regulates A Pan-Cancer Network Of Co-Expressed Oncogenic Splicing Factors., Laura M Urbanski, Mattia Brugiolo, Sunghee Park, Brittany Lynn Angarola, Nathan Leclair, Marina Yurieva, Phil Palmer, Sangram Keshari Sahu, Olga Anczuków

Faculty Research 2022

MYC is dysregulated in >50% of cancers, but direct targeting of MYC has been clinically unsuccessful. Targeting downstream MYC effector pathways represents an attractive alternative. MYC regulates alternative mRNA splicing, but the mechanistic links between MYC and the splicing machinery in cancer remain underexplored. Here, we identify a network of co-expressed splicing factors (SF-modules) in MYC-active breast tumors. Of these, one is a pan-cancer SF-module correlating with MYC activity across 33 tumor types. In mammary cell models, MYC activation leads to co-upregulation of pan-cancer module SFs and to changes in >4,000 splicing events. In breast cancer organoids, co-overexpression of the …


Usa V. Thomas Lanzana Nov 2022

Usa V. Thomas Lanzana

2022 Decisions

USDC for the District of New Jersey


Patterns Of Utilization And Clinical Adoption Of 0.35 Tesla Mr-Guided Radiation Therapy In The United States - Understanding The Transition To Adaptive, Ultra-Hypofractionated Treatments, Michael D. Chuong, Mary Ann Clark, Lauren E. Henke, Amar U. Kishan, Lorraine Portelance, Parag J. Parikh, Michael F. Bassetti, Himanshu Nagar, Stephen A. Rosenberg, Minesh P. Mehta, Tamer Refaat, Justin M. Rineer, Adam Smith, Steven Seung, Bassem I. Zaki, Martin Fuss, Raymond H. Mak Nov 2022

Patterns Of Utilization And Clinical Adoption Of 0.35 Tesla Mr-Guided Radiation Therapy In The United States - Understanding The Transition To Adaptive, Ultra-Hypofractionated Treatments, Michael D. Chuong, Mary Ann Clark, Lauren E. Henke, Amar U. Kishan, Lorraine Portelance, Parag J. Parikh, Michael F. Bassetti, Himanshu Nagar, Stephen A. Rosenberg, Minesh P. Mehta, Tamer Refaat, Justin M. Rineer, Adam Smith, Steven Seung, Bassem I. Zaki, Martin Fuss, Raymond H. Mak

Radiation Oncology Articles

PURPOSE/OBJECTIVE: Magnetic resonance-guided radiation therapy (MRgRT) utilization is rapidly expanding worldwide, driven by advanced capabilities including continuous intrafraction visualization, automatic triggered beam delivery, and on-table adaptive replanning (oART). Our objective was to describe patterns of 0.35Tesla(T)-MRgRT (MRIdian) utilization in the United States (US) among early adopters of this novel technology.

MATERIALS/METHODS: Anonymized administrative data from all US MRIdian treatment systems were extracted for patients completing treatment from 2014 to 2020. Detailed treatment information was available for all MRIdian linear accelerator (linac) systems and some cobalt systems.

RESULTS: Seventeen systems at 16 centers delivered 5736 courses and 36,389 fractions (fraction details …


Why Arts Education, At All?: An A/R/Tographic Inquiry, Darshana Devarajan, Brittany M. Brewer, Karenanna Boyle Creps, Reyila Hadeer Nov 2022

Why Arts Education, At All?: An A/R/Tographic Inquiry, Darshana Devarajan, Brittany M. Brewer, Karenanna Boyle Creps, Reyila Hadeer

Northwest Journal of Teacher Education

In the wake of curricular epistemicide, the authors draw your attention towards the theoretical and practical constraints created around arts education. As a/r/tographers (artists, researchers, and teachers), we argue that our ways of knowing and creating in the space of curriculum and instruction are dynamic ways to think about and through curricular epistemicide. In foregrounding our own experiences of “(un)becoming through the cracks”, when we are faced with restrictive ways of knowing in a Department of Teacher Education, we put forth a question through our arts-based practices of knowing: why arts education, at all?


Shan Chaudhary V. Attorney General United States Nov 2022

Shan Chaudhary V. Attorney General United States

2022 Decisions

Agency


Acafinder: Genome Mining For Anti-Crispr-Associated Genes, Bowen Yang, Jinfang Zheng, Yanbin Yin Nov 2022

Acafinder: Genome Mining For Anti-Crispr-Associated Genes, Bowen Yang, Jinfang Zheng, Yanbin Yin

Food for Health: Publications

Anti-CRISPR (Acr) proteins are encoded by (pro)viruses to inhibit their host’s CRISPR-Cas systems. Genes encoding Acr and Aca (Acr associated) proteins often colocalize to form acr-aca operons. Here, we present AcaFinder as the first Aca genome mining tool. AcaFinder can (i) predict Acas and their associated acr-aca operons using guilt-by-association (GBA); (ii) identify homologs of known Acas using an HMM (Hidden Markov model) database; (iii) take input genomes for potential prophages, CRISPR-Cas systems, and self-targeting spacers (STSs); and (iv) provide a standalone program (https://github.com/boweny920/AcaFinder) and a web server (http://aca .unl.edu/Aca). AcaFinder was applied to mining over …


2022-11-22_Michiganoverview_Covidstats, Michigan Department Of Health & Human Services Nov 2022

2022-11-22_Michiganoverview_Covidstats, Michigan Department Of Health & Human Services

Cumulative Michigan COVID-19 Data

The COVID Overview page was obtained from Michigan's main COVID-19 page: https://www.michigan.gov/coronavirus/stats.

The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled. COVID case and testing data will be posted once a week on Tuesdays.

This report is provisional and subject to change. City of Detroit and Wayne County are reported separately. MDHHS began tracking probable cases April 5, 2020. FCI indicates federal correctional institute. MDOC indicates Michigan Department of Corrections. Diagnostic tests, including nucleic acid amplification/real-time polymerase chain reaction (NAAT/RT-PCR) …


Brief Of Law Professors As Amici Curiae In Support Of Applicants’ Application To Vacate The Injunction Entered By The United States Court Of Appeals For The Eighth Circuit, Pamela Foohey Nov 2022

Brief Of Law Professors As Amici Curiae In Support Of Applicants’ Application To Vacate The Injunction Entered By The United States Court Of Appeals For The Eighth Circuit, Pamela Foohey

Amicus Briefs

Amici curiae Dean Erwin Chemerinsky and Professors William Araiza, Matthew Bruckner, Pamela Foohey, Jonathan Glater, Luke Herrine, Dalié Jiménez, Jeffrey Lubbers, Chrystin Ondersma, Peter Shane, and Peter Strauss are professors of law at universities throughout the United States, with expertise in student financial assistance programs under Title IV of the Higher Education Act of 1965 and administrative and constitutional law. Amici file this brief in support of Applicants because this case presents important questions within amici’s professional expertise, namely, the scope of the Department of Education’s authority to provide relief to borrowers and the development of this Court’s statutory …


High-Metabolism Infrastructure And The Scrap Industry In Urban China, Adam Liebman Nov 2022

High-Metabolism Infrastructure And The Scrap Industry In Urban China, Adam Liebman

Sociology & Anthropology Faculty publications

Abstract

Rapid urbanization in 21st-century China has been fraught with contested demolition, overdevelopment and shoddy infrastructure with short lifespans. By viewing this infrastructure as having “high metabolism” and examining the urban scrap trade that is fuelled by its material outputs, this article challenges a common assumption that such a form of urbanization is merely wasteful and problematic. Crucially, such urbanization also puts rural migrants and scrap into motion in a way that helps to reproduce its form. This occurs by generating socio-material nodes of scrap trading wherein migrants make the most of temporarily stable situations with entrepreneurialism. The nodes are …


Hydroponics And Vertical Farming Methods, John Rose Nov 2022

Hydroponics And Vertical Farming Methods, John Rose

D.U.Quark

No abstract provided.


2022-11-22_Michiganoverview_Covidlongtermcare, Michigan Department Of Health & Human Services Nov 2022

2022-11-22_Michiganoverview_Covidlongtermcare, Michigan Department Of Health & Human Services

Michigan COVID-19 Long Term Care Data

The COVID Long Term Care Facilities page was obtained from Michigan's COVID-19 data page: https://www.michigan.gov/coronavirus/stats/data-about-places/long-term-care-data.

This report is created by the Michigan Department of Health & Human Services from data self-reported by long-term care facilities into EMResource. Data for all reporting facilities is posted weekly each Monday.

The information below represents COVID-19 data reported directly to MDHHS by licensed and operating Skilled Nursing, Home for the Aged and Adult Foster Care facilities (licensed to serve 13 or more individuals) in Michigan from January 1, 2020. All long-term care facilities additionally have an obligation to report COVID-positive residents and/or staff …


Ole Miss, Msu Cadets Leg 100 Miles For Egg Bowl Run, Clara Turnage Nov 2022

Ole Miss, Msu Cadets Leg 100 Miles For Egg Bowl Run, Clara Turnage

University of Mississippi News

ROTC students relayed from Starkville to Oxford to deliver game ball


Covid-19 Newsletter (Vol. 146), Center For Disaster Medicine, New York Medical College Nov 2022

Covid-19 Newsletter (Vol. 146), Center For Disaster Medicine, New York Medical College

COVID-19 Newsletter

No abstract provided.


Confronting Curriculum Epistemicide: A Conversation With Editors Dan Ness & Rick Sawyer, Maika Yeigh, Richard D. Sawyer, Daniel Ness Nov 2022

Confronting Curriculum Epistemicide: A Conversation With Editors Dan Ness & Rick Sawyer, Maika Yeigh, Richard D. Sawyer, Daniel Ness

Northwest Journal of Teacher Education

As an entree into the Special Issue "Confronting Curriculum Epistemicide", NWJTE co-editor Maika Yeigh talk with editors Daniel Ness and Richard Sawyer to learn about their inspiration and goals of the Special Issue.


November 22, 2022 Ereporter, University Of Alabama At Birmingham Nov 2022

November 22, 2022 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.


Myostatin Is A Negative Regulator Of Adult Neurogenesis After Spinal Cord Injury In Zebrafish, Vishnu Muraleedharan Saraswathy, Lili Zhou, Anthony R Mcadow, Brooke Burris, Deepika Dogra, Sven Reischauer, Mayssa H Mokalled Nov 2022

Myostatin Is A Negative Regulator Of Adult Neurogenesis After Spinal Cord Injury In Zebrafish, Vishnu Muraleedharan Saraswathy, Lili Zhou, Anthony R Mcadow, Brooke Burris, Deepika Dogra, Sven Reischauer, Mayssa H Mokalled

2020-Current year OA Pubs

Intrinsic and extrinsic inhibition of neuronal regeneration obstruct spinal cord (SC) repair in mammals. In contrast, adult zebrafish achieve functional recovery after complete SC transection. While studies of innate SC regeneration have focused on axon regrowth as a primary repair mechanism, how local adult neurogenesis affects functional recovery is unknown. Here, we uncover dynamic expression of zebrafish myostatin b (mstnb) in a niche of dorsal SC progenitors after injury. mstnb mutants show impaired functional recovery, normal glial and axonal bridging across the lesion, and an increase in the profiles of newborn neurons. Molecularly, neuron differentiation genes are upregulated, while the …


Chatbot-Delivered Cognitive Behavioral Therapy In Adolescents With Depression And Anxiety During The Covid-19 Pandemic: Feasibility And Acceptability Study, Ginger Nicol, Ruoyun Wang, Sharon Graham, Sherry Dodd, Jane Garbutt Nov 2022

Chatbot-Delivered Cognitive Behavioral Therapy In Adolescents With Depression And Anxiety During The Covid-19 Pandemic: Feasibility And Acceptability Study, Ginger Nicol, Ruoyun Wang, Sharon Graham, Sherry Dodd, Jane Garbutt

2020-Current year OA Pubs

BACKGROUND: Symptoms of depression and anxiety, suicidal ideation, and self-harm have escalated among adolescents to crisis levels during the COVID-19 pandemic. As a result, primary care providers (PCPs) are often called on to provide first-line care for these youth. Digital health interventions can extend mental health specialty care, but few are evidence based. We evaluated the feasibility of delivering an evidence-based mobile health (mHealth) app with an embedded conversational agent to deliver cognitive behavioral therapy (CBT) to symptomatic adolescents presenting in primary care settings during the pandemic.

OBJECTIVE: In this 12-week pilot study, we evaluated the feasibility of delivering the …