Digital Commons Network^™

Viewing Animal Migration Through A Social Lens, Ellen O. Aikens, Iris D. Bontekoe, Lara Blumenstiel, Anna Schlicksupp, Andrea Flick

Natural Resource Management Faculty Publications

Evidence of social learning is growing across the animal kingdom. Researchers have long hypothesized that social interactions play a key role in many animal migrations, but strong empirical support is scarce except in a few unique systems and species. In this review, we aim to catalyze advances in the study of social migrations by synthesizing research across disciplines and providing a framework for understanding when, how, and why social influences shape the decisions animals make during migration. Integrating research across the fields of social learning and migration ecology will advance our understanding of the complex behavioral phenomena of animal migration …

A Comparison Of Mini-Flotac And Mcmaster Techniques, Overdispersion And Prevalence Of Parasites In Naturally Infected North American Bison (Bison Bison) In The Usa, Wiliam L. Johnson, Samantha Reynolds, Colton L. Adkins, Bradly Wehus-Tow, Jameson R. Brennan, Catherine B. Krus, Danielle Buttke, Jeff M. Martin, Jeba R.J. Jesudoss Chelladurai

Natural Resource Management Faculty Publications

Several quantitative diagnostic techniques are available to estimate gastrointestinal parasite counts in the feces of ruminants. Comparing egg and oocyst magnitudes in naturally infected samples has been a recommended approach to rank fecal techniques. In this study, we compared the Mini-FLOTAC (sensitivity of 5 eggs per gram (EPG)/oocysts per gram (OPG)) and different averaged replicates of the modified McMaster techniques (sensitivity of 33.33 EPG/OPG) in 387 fecal samples from 10 herds of naturally infected North American bison in the Central Great Plains region of the USA. Both techniques were performed with fecal slurries homogenized in a fill-FLOTAC device. In the …

Networking Voices Against Violence: Online Activism And Transnational Feminism In Local-Global Contexts, Sutanuka Banerjee, Lipika Kankaria

Wagadu: A Journal of Transnational Women's & Gender Studies

Contemporary feminism manifests itself in the form of blogs, hashtags, e-magazines, and digitally planned protests through online communities that address the prevailing concerns of feminists in the digital age. This feminist approach to digital activism aims to reclaim the power of technology which is inherently hegemonic and masculinist by creating alternate spaces and modes of protest. Transnational feminism is increasingly being shaped by online discourses and the new digital space enables social movements in shaping feminist solidarity and complex netizen identities. This paper adopts discourse analysis of online contents that question the prevalent patriarchal system in South Asia and thus …

Visiting The House Of Bad's Mother: Queering Saadat Hasan Manto's “Thanda Gosht”, Namita Goswami

Wagadu: A Journal of Transnational Women's & Gender Studies

This essay reads Saadat Hasan Manto's short story, “Thanda Gosht” (1950), depicting women's experience of sectarian brutality during the 1947 partition of India and Pakistan, to delineate the postcolonial significance Gayatri Spivak's concept of originary queerness. Manto's synecdoche (“cold meat”) for an unnamed and raped female corpse, her Sikh abductor and violator, as well as for the story's readers, (re)figures reproductive heteronormativity as a process of unknowing that emplaces a gendered taxonomy, even when its victims are silent. Rather than reinforce sexual difference as a finished itinerary, however, Kulwant Kaur's repeatedly piercing question—who she is—queers “Thanda Gosht” by …

Double Bind Of Muslim Women's Activism In Pakistan: Case Of Malala Yousafzai And Sharmeen Obaid-Chinoy, Naila Sahar

Wagadu: A Journal of Transnational Women's & Gender Studies

A majority of Western2 feminist studies has dealt with women from the third world as a homogenous entity of poor and passive victims without agency, who need saving and thus need to be spoken for. Chandra Talpade Mohanty and Gayatri Chakravorty Spivak have both underscored the urgency of seeing and dealing with third world feminism in terms of a genre that is different in socio-cultural background from Western dynamics, and they emphasize the importance of being wary of the ways in which Western feminism creates the 'discursive homogenization and systematization of the oppression of women in the Third World' (Mohanty, …

Cholinergic Receptor-Wnt Pathway Controls Immune Activation By Sensing Intestinal Dysfunction, Jie Ren, Yu Sang, Alejandro Aballay

Faculty, Staff and Student Publications

Alterations in the intestinal physiology caused by pathogen colonization result in immune activation. To provide insights into the mechanisms underlying the control of immune activation by changes in intestinal homeostasis, we conducted a forward genetic screen for suppressors of immune activation by intestinal distension in Caenorhabditis elegans. Our results indicate that C. elegans ACC-4, a member of a family of acetylcholine receptors, is required in immune activation by defects in the defecation motor program or by pathogen infection. ACC-4 acts postsynaptically in non-cholinergic RIM neurons to regulate several immune genes and a Wnt-mediated host immune response. These findings uncover a …

Bile Acids Regulate The Epithelial Na+ Channel In Native Tissues Through Direct Binding At Multiple Sites, Xue-Ping Wang, Viktor Tomilin, Andrew J Nickerson, Runze Tian, Merve Ertem, Abagail Mckernan, Xiaoguang Lei, Oleh Pochynyuk, Ossama B Kashlan

Faculty, Staff and Student Publications

Bile acids, originally known to emulsify dietary lipids, are now established signalling molecules that regulate physiological processes. Signalling targets several proteins that include the ion channels involved in regulating intestinal motility and bile viscosity. Studies show that bile acids regulate the epithelial sodium channel (ENaC) in cultured cell models and heterologous expression systems. ENaC plays both local and systemic roles in regulating extracellular fluids. Here we investigated whether bile acids regulate ENaC expressed in native tissues. We found that taurocholic acid and taurohyodeoxycholic acid regulated ENaC in both the distal nephron and distal colon. We also tested the hypothesis that …

Immune Dysfunction Signatures Predict Outcomes And Define Checkpoint Blockade-Unresponsive Microenvironments In Acute Myeloid Leukemia, Sergio Rutella, Jayakumar Vadakekolathu, Francesco Mazziotta, Stephen Reeder, Tung-On Yau, Rupkatha Mukhopadhyay, Benjamin Dickins, Heidi Altmann, Michael Kramer, Hanna A Knaus, Bruce R Blazar, Vedran Radojcic, Joshua F Zeidner, Andrea Arruda, Bofei Wang, Hussein A Abbas, Mark D Minden, Sarah K Tasian, Martin Bornhäuser, Ivana Gojo, Leo Luznik

Faculty, Staff and Student Publications

Background

Immune exhaustion and senescence are dominant dysfunctional states of effector T cells and major hurdles for the success of cancer immunotherapy. In the current study, we characterized how acute myeloid leukemia (AML) promotes the generation of senescent-like CD8⁺ T cells and whether they have prognostic relevance.

METHODS

We analyzed NanoString, bulk RNA-Seq and single-cell RNA-Seq data from independent clinical cohorts comprising 1,896 patients treated with chemotherapy and/or immune checkpoint blockade (ICB).

Results

We show that senescent-like bone marrow CD8⁺ T cells were impaired in killing autologous AML blasts and that their proportion negatively correlated with overall survival …

Criminal Law And Procedure, Brittany A. Dunn-Pirio, Timothy J. Huffstutter, Mason D. Williams, Robin M. Nagel, Tanner M. Russo

University of Richmond Law Review

This Article surveys recent developments in criminal procedure and law in Virginia. Because of space limitations, the authors have limited their discussion to the most significant published appellate decisions and legislation.

George Floyd In Papua: Image-Events And The Art Of Resonance, Karen Strassler

Publications and Research

This article offers an introduction to the “image-event” as both concept and method through a focus on the circulation of images around the killing of George Floyd. It examines how these images reverberated and resonated in West Papua, a restive region of Indonesia that has been the site of a long-standing separatist movement. It critically examines a celebratory media discourse that sees the US-based Black Lives Matter movement as expanding outward to spark similar movements elsewhere, a logic that reiterates long-standing colonialist narratives that figure places like Papua as backwaters belatedly receiving and imitatively taking up ideas that flow from …

Simple Organic Fertilizer Amendments For Farming In Degraded Soils: Effects On Plant-Microbe Interactions, Andrew Adamski

All NMU Master's Theses

The rapid loss of topsoil, biodiversity, and water quality across agricultural land in the United States and the industrialized world poses some of the most important risks to the future of global and domestic food security. Not only is arable land being lost at an unsustainable pace, but the average age of farmers has also steadily been rising due to a myriad of barriers young, BIPOC (Black, Indigenous, and People of Color), and beginning farmers face. In an attempt to address these issues, worm castings, bokashi tea, fish hydrolysate, and biochar were applied alone and in combination to an extremely …

Stability Of Fishes Assemblage Structure Over A Lustrum In Coastal Wetlands Under Different Disturbances In An Industrial Zone Of The Central Gulf Of Mexico Coast, Carlos E. Cintra-Buenrostro, Alejandro Fierro-Cabo

School of Earth, Environmental, & Marine Sciences Faculty Publications

Shallow coastal wetlands within the territory of an industrial port in southern Tamaulipas, Mexico, were monitored seasonally over a lustrum, focusing on their fishes assemblage and water parameters. The purpose was to characterize these ecosystems that are affected by different disturbances of industrial origin, document changes, and assess potentially degrading terms as the affectations prevailed over the period of study. The wetlands are differentially affected by impacting land uses in their immediate surroundings, by crude oil leaks, and/or by diverse industrial wastewater discharges. Water parameters varied only slightly over time for most sites, and relative disparities among sites remained. The …

Prevalence And Sociodemographic Profiles Of Grand Multipara In Abu Dhabi, United Arab Emirates, Zainab Taha, Farid El Ktaibi, Aysha Ibrahim Al Dhaheri, Dimitrios Papandreou, Ahmed Ali Hassan

All Works

The literature shows that grand multipara mothers are major contributors to poor maternal and perinatal health compared to multipara mothers. Data regarding parity profiles are essential, especially in rapidly transforming countries such as the United Arab Emirates (UAE). This study aimed to investigate the prevalence and factors associated with multipara mothers compared to multipara mothers in Abu Dhabi, UAE. The data were collected from seven health care centers located in Abu Dhabi.From1818 enrolled mothers, the prevalence of grand multipara was 135(7.4%, 95% Confidence Interval (CI) = 7.2, 7.6). In logistic regression analysis, factors associated positively with grand multipara were a …

Catalytic Reduction Of Dyes And Antibacterial Activity Of Agnps@Zn@Alginate Composite Aerogel Beads, Fadila Benali, Bouhadjar Boukoussa, Nour El Houda Benkhedouda, Amina Cheddad, Ismail Issam, Jibran Iqbal, Mohammed Hachemaoui, Mohamed Abboud, Adel Mokhtar

All Works

This work focuses on the preparation of aerogel composite beads based on Zn(II)-crosslinked alginate and loaded with different percentages of AgNPs using a simple approach. The obtained samples were evaluated in two different applications: the first application consists in their use as catalysts for the reduction of MB, MO, OG and CR dyes in a simple and binary system under the presence of NaBH4. For this, several parameters affecting the catalytic behavior of these catalysts have been investigated and discussed such as the catalyst mass, AgNPs content, dye nature, and the selectivity of the catalyst in a binary system. The …

Tracking The Associative Boost In Infancy, Kim Plunkett, Luche C Delle, Thomas Hills, Caroline Floccia

School of Psychology

Do words that are both associatively and taxonomically related prime each other in the infant mental lexicon? We explore the impact of these semantic relations in the emerging lexicon. Using the head-turn preference procedure, we show that 18-month-old infants have begun to construct a semantic network of associatively and taxonomically related words, such as dog-cat or apple-cheese. We demonstrate that priming between words is longer-lasting when the relationship is both taxonomic and associative, as opposed to purely taxonomic, reflecting the associative boost reported in the adult priming literature. Our results demonstrate that 18-month-old infants are able to construct a lexical-semantic …

Cerebellar Coordination Of Neuronal And Behavioral Rhythms, Brittany Correia Chapman

Theses and Dissertations (ETD)

Long known for its role in motor control, it is increasingly clear that the cerebellum is also involved in numerous cognitive and affective behaviors. Though the neuronal mechanism for the role of the cerebellum in cognition is still unclear, there is a consensus that it involves cerebellar interactions with the cerebral cortex. Recent studies suggest that the cerebellum monitors, and possibly coordinates, the precise phase alignment or coherence of neuronal oscillations in cerebral cortical areas. Here, we asked how loss of cerebellar function affects respiratory rhythms and the interactions of local field potential (LFP) oscillations between the lobulus simplex (LS) …

Risk For Preeclampsia Associated With Nutritional Deficiencies And Modified By Apol1 Genotype, Winter S. Bruner

Theses and Dissertations (ETD)

Preeclampsia (PE) is a hypertensive disorder of pregnancy that is associated with micronutrient deficiencies. Nutrients involved in placental health and maintenance, such as vitamin D and folate, are important nutrients to assess in the risk of PE. As gestational age increases, the levels of vitamin D and folate potentially have incrementally increasing concentrations associated with PE. In addition to micronutrient deficiencies, PE is also associated with the presence of APOL1 high-risk (HR) variants. It was also hypothesized that a potential additive effect exists between HR APOL1 genotype status and nutritional deficiencies that would place individuals at a higher risk of …

The Impact Of Covid-19 On Children And Adolescents’ Mental Health, Tamara A. Hafiz, Ahmed H. Aljadani

Saudi Medical Journal

Children and adolescents are more susceptible to the formation of mental health issues, since their brains are still developing. The coronavirus disease 19 (COVID-19) pandemic response measures have disrupted daily life and left individuals socially isolated, including children and adolescents. In view of this, this study aimed to give a narrative review of the literature on the pandemic’s effects on children’s and adolescents’ mental health, associated risks, and successful intervention strategies. There are still issues to be resolved to give children and adolescents in many regions of the world with quality, rights-based, and culturally relevant mental health care. It is …

Determinants Of Egg Consumption By Infants And Young Children In Ethiopia, Bezawit E. Kase, Edward A. Frongillo Jr. Ph.D., Sejla Isanovic, Wendy Gonzalez, Hana Yemane Wodajo, Eric W. Djmeu

Faculty Publications

Objective:

To identify determinants of egg consumption in infants and young children aged 6–23·9 months in Ethiopia. Design and setting:

Data used were from the cross-sectional baseline survey of an egg campaign in Ethiopia implemented by the Global Alliance for Improved Nutrition. Participants:

Children aged 6–23·9 months (n 453) were sampled. Data on socio-demographic characteristics, economic resources, caregiver’s behaviour, child health and feeding practices, and egg consumption in the last 7 d were collected using interviewer-administered questionnaires. Multivariable ordinal logistic regression was used to examine the association between explanatory variables and egg consumption in the last 7 d. Results:

About …

Nf-Κb Represses Retinoic Acid Receptor–Mediated Gprc5a Transactivation In Lung Epithelial Cells To Promote Neoplasia, Hongyong Song, Xiaofeng Ye, Yueling Liao, Siwei Zhang, Dongliang Xu, Shuangshuang Zhong, Bo Jing, Tong Wang, Beibei Sun, Jianhua Xu, Wenzheng Guo, Kaimi Li, Min Hu, Yanbin Kuang, Jing Ling, Tuo Zhang, Yadi Wu, Jing Du, Feng Yao, Y. Eugene Chin, Qi Wang, Binhua P. Zhou, Jiong Deng

Markey Cancer Center Faculty Publications

Chronic inflammation is associated with lung tumorigenesis, in which NF-κB–mediated epigenetic regulation plays a critical role. Lung tumor suppressor G protein–coupled receptor, family C, member 5A (GPRC5A), is repressed in most non–small cell lung cancer (NSCLC); however, the mechanisms remain unclear. Here, we show that NF-κB acts as a transcriptional repressor in suppression of GPRC5A. NF-κB induced GPRC5A repression both in vitro and in vivo. Intriguingly, transactivation of NF-κB downstream targets was not required, but the transactivation domain of RelA/p65 was required for GPRC5A repression. NF-κB did not bind to any potential cis-element in the GPRC5A promoter. Instead, p65 was …

Murrells Inlet Assessment 2022, Lindsay Brown, Katelyn Cilino, Aaron Osborn, Adeline Dinch, Jaelynne Harriot, Hannah Hicks, Brooke Holmes, Daniel Maddaloni, Jenna Monore, Mackenzie Ptasienski, Piper Pratt, Jordan Roballo, Brandon Roberts, Sophie Sherwood, Madison Smith, Holly Taylor

Goal 15: Life on Land

No abstract provided.

Olfactory Processing In The Piriform Cortex Of Awake, Freely Moving Mice, Ian F. Chapman

Theses and Dissertations (ETD)

The piriform cortex (PC) has long been established as the primary cortical recipient of olfactory information in the mammalian brain. In rodents, information extracted from recordings of PC neurons can accurately decode the identity of odors, leading to delineation of PC as the primary cortical region involved in the formation of odor perception. Unfortunately, due to technical limitations, many of the prior studies establishing these coding principles were performed without the ability to track the responses of the same cells over time. Additionally, recordings have often relied on head-fixation to minimize diffusion of odor stimuli, limiting movement range and natural …

A Method Of Assessing Peripheral Stent Abrasiveness Under Cyclic Deformations Experienced During Limb Movement, Courtney Keiser, Kaspars Maleckis, Pauline Struczewska, Majid Jadidi, Jason N. Mactaggart, Alexey Kamenskiy

Department of Mechanical and Materials Engineering: Faculty Publications

Poor outcomes of peripheral arterial disease stenting are often attributed to the inability of stents to accommodate the complex biomechanics of the flexed lower limb. Abrasion damage caused by rubbing of the stent against the artery wall during limb movement plays a significant role in reconstruction failure but has not been characterized. Our goals were to develop a method of assessing the abrasiveness of peripheral nitinol stents and apply it to several commercial devices. Misago, AbsolutePro, Innova, Zilver, SmartControl, SmartFlex, and Supera stents were deployed inside electrospun nanofibrillar tubes with femoropopliteal artery-mimicking mechanical properties and subjected to cyclic axial compression …

“Biophilia As A Sustainable Design Approach For University Buildings Design: A Case Study In University Campus Drawing Studios Cairo, Egypt, Amira Mohamed Mahrous, Khaled M. Dewidar, Mostafa Mohamed Refaat, Ashraf Nessim

Architectural Engineering

University campuses have a long history of enriching the social, cultural, and economic value of societies. Worldwide, there is a rising demand for the integration of new approaches into the planning and design of university buildings to further improve their quality. According to the literature, many approaches needed to be considered while designing university buildings that can enhance students’ performance. Biophilic design is known to have enhancing levels of interaction, and interaction patterns, enhancing health and wellbeing in terms of physiological, psychological, cognitive, and social/ spiritual benefits, while rigorous scientific evidence that supports such claims is rare. Many researchers have …

An Overview Of Pathophysiology And Treatment Options Of Osteonecrosis Of Femoral Head In Sickle Cell Disease, Mohammed L. Al-Otaibi

Saudi Medical Journal

Osteonecrosis of the femoral head (ONFH) is the most prevalent musculoskeletal pathologic manifestation of sickle cell disease (SCD) resulting in an osteonecrotic event. This review aimed to summarize mechanisms involved in pathophysiology of ONFH and treatment options available in Saudi Arabia to treat SCD patients with complication of osteonecrotic event. The pathophysiology of ONFH include genetic and micro particles involvement. The progression of osteonecrosis involves reduced levels of bioactive compounds in peripheral blood mononuclear cells and elevated CD4+T circulating levels to stimulate pro-inflammatory cytokines contributing to inflammation at target site. Initial treatment approach is pharmacological agents use to mitigate risk. …

Sevoflurane Reverses Cisplatin Resistance In Neuroblastoma Cells Through The Linc00473/Mir-490-5p/Akt1 Axis, Huiqing Li, Xiaobo Fu, Huiyu Guo, Yue Sun, Di Wang, Zengzhen Zhang

Saudi Medical Journal

Objectives: To determine whether sevoflurane regulates cisplatin resistance in neuroblastoma cells. Methods: The SH-SY5Y cell line with cisplatin-resistant phenotype (SH-SY5Y-SR) was generated. Cells were co-treated with sevoflurane and cisplatin to seek the sevoflurane function on cisplatin resistance. Key targets of sevoflurane treatment were determined using sequencing (ribonucleic acid [RNA-seq]). Cells were then transfected with specific vectors. Linc00473 and microRNA-490-5p (miR-490-5p) levels were detected using reverse transcriptase quantitative real-time reverse transcription PCR (RT-qPCR). Linc00473-miR-490-5p binding was confirmed using a luciferase reporter-gene assay. After treatment, cell proliferation, viability, and caspase-3 activity were measured to determine the effects of treatment on tumor cells. …

Modifications Of Cellulose-Based Biomaterials For Biomedical Applications, Nour Fatema, Ruben Michael Ceballos, Chenguang Fan

Chemistry & Biochemistry Faculty Publications and Presentations

Cellulose is one of the most abundant organic compounds in nature and is available from diverse sources. Cellulose features tunable properties, making it a promising substrate for biomaterial development. In this review, we highlight advances in the physical processes and chemical modifications of cellulose that enhance its properties for use as a biomaterial. Three cellulosic products are discussed, including nanofibrillated, nanocrystalline, and bacterial cellulose, with a focus on how each may serve as a platform for the development of advanced cellulose-based biomaterials for Biomedical applications. In addition to associating mechanical and chemical properties of cellulosic materials to specific applications, a …

Computational Simulations Of The Effects Of Gravity On Lymphatic Transport, Huagian Wei, Huabing Li, Timothy P. Padera, James W. Baish, Lance L. Munn

Faculty Journal Articles

Physical forces, including mechanical stretch, fluid pressure and shear forces alter lymphatic vessel contractions and lymph flow. Gravitational forces can affect these forces, resulting in altered lymphatic transport, but the mechanisms involved have not been studied in detail. Here, we combine a lattice Boltzmann-based fluid dynamics computational model with known lymphatic mechanobiological mechanisms to investigate the movement of fluid through a lymphatic vessel under the effects of gravity that may either oppose or assist flow. Regularly spaced, mechanical bi-leaflet valves in the vessel enforce net positive flow as the vessel walls contract autonomously in response to calcium and nitric oxide …

Understanding Terrorism: An Alternative View And The Painful Truth: How Powerful Nations Legitimize Terrorism, Kwame B. Antwi-Boasiako, Cindy P. Davis

Journal of Terrorism Studies

Despite human beings’ noble achievements on this planet including medicine, technology, physics, and chemistry, there is one characteristic of humans, which is disturbing and that act is “committing extreme cruelty and violence against its own species” (Smith 2007:41). This cruelty by human beings against themselves stems from many factors including power, ideology, religion, and terrorism. These categorizations, as Smith (2011) noted, are unfortunately used to dehumanize the other through societal definitions where one group, the powerful, sees itself as the paragons of civilization against the other, the weak, as barbarians. Terrorism, racism, ideology, and religion are but some of the …

Resilience Against Banditry And Insurgency In Niger State, Nigeria (2015 To 2022), Kamar Hamza, Hauwa'u Evelyn Yusuf Professor, Abubakar Yabagi Akote, Bello Balarabe Abubakar

Journal of Terrorism Studies

The twin evil of banditry and insurgency are threatening the peace of law abiding citizens in rural communities in Niger State, Nigeria. These activities are being noticed from 2015 to 2022. These challenges have made rural dwellers to leave their ancestral home to search for places of abode for the main time. Notwithstanding the people of these communities are still fighting the bandits and insurgents through both government efforts and their own community initiatives. This article investigated the way the communities have suffered in the hands of bandits and insurgents and how they have been confronting them to take control …