Digital Commons Network^™

A Novel Drug To Induce Apoptosis In Advanced Prostate Cancer Cells, Parshva A. Sanghvi

Honors Undergraduate Theses

Prostate cancer is one of the leading causes of death for men in America as approximately 1 in 41 men will have prostate cancer. In this research, we focus on enzalutamide-resistant prostate cancer cells as cell resistance to enzalutamide is a prevalent obstacle in treating prostate cancer. We tested a novel compound library at different doses and observed each compound's efficacy in inducing apoptosis in enzalutamide-resistant cells. Furthermore, we analyzed the mechanism by which apoptosis was induced in compounds that showed a high efficacy at lower doses. Overall, we found that Darapladib shows promising results in treating cells that have …

Fanboys, Pow, & Mount Plot: Mnemonic Devices Used In Teaching Writing, Sarah Anderson, Alexa Bills, Kaitlyn Conlin, Eve Crawford, Natalie Eggli, Jenae Grant, Lilly Hammer, Andrew Isaacson, Kassandra Jimenez, Ryan Mansfield, Brindley Rowley, Samantha Stringham, Meghan Waldenberg, Brady Wallis, Joyce Kinkead

The Utah English Journal

Cicero ( 106-43 BCE) was renowned during his lifetime and influential long after as an extraordinary orator and writer, able to recall long speeches from memory. A technique termed the memory palace, which associates memory with locations-also called method of loci-enabled ancient rhetoricians to deliver stimulating speeches. Retention of information was essential for delivering speeches not just because it was impressive but also due to the paucity of writing materials. Writers and orators relied on wax tablets that could be inscribed with a stylus but could not archive the text; as a result, the information had to be memorized, part …

Uri Undergraduate And Graduate Course Catalog 2022-2023, University Of Rhode Island

URI Course Catalogs Archive

This is a downloadable PDF version of the University of Rhode Island course catalog.

Biochar From Empty Date Fruit Bunch As An Adsorbent To Remove Eriochrome Black T And Methylene Blue From Aqueous Solution, Houari Bella, Hayet Bendaikha

Applied Environmental Research

Date fruit has a significant role in Sahara countries' economies. In this study, a bunch of empty dates waste was used to produce biochar, which will be used to adsorb Eriochrome black T (EBT) and methylene blue (MB) dyes from aqueous solution. The dates bunch was washed, dried, and ground into small particles. Then it was heated in a muffle furnace at 850 °C. The biochar from empty date bunches (BEDB) characteristics before and after adsorption was determined by using scanning electron microscopy (SEM) and Fourier transform infrared (FTIR) spectroscopy. The experiment has used different parameters notably initial concentration (25 …

Efficacy Of Prebiotic Dietary Intervention To Mitigate Risks For Dementia Via The Gut-Brain Axis, Lucille M. Yanckello

Theses and Dissertations--Pharmacology and Nutritional Sciences

Alzheimer’s disease (AD) is the most common form of dementia with various risk factors including age, environmental factors such as brain injury and genetic factors, such as the E4 allele of the Apolipoprotein gene. Presence of the APOE4 allele increases AD risk by two- to four- fold. Recent studies have shown that mild traumatic brain injury (mTBI), even without loss of consciousness, increases risk of dementia diagnosis by more than two-fold in military personnel and is also a significant environmental risk factor for developing dementia in the general population. The gut-brain axis (GBA) or bi-directional communication between the brain and …

Dementia Care Among Somali Elders, Emmanuel Asante Opoku

All Graduate Theses, Dissertations, and Other Capstone Projects

Caring for persons with dementia is demanding and complicated since there is “no one-size-fits all formula for dementia care. The care needs to be modified to fit the various stages of the condition and each family's unique situation. Racial and ethnic differences place unique demand on all the forms of dementia care; in-home care (IHC), long-term care (LTC), adult day centers(ADC), short term care (STC) and hospice care (HC).

This paper aimed to study how Somali elders think and interact with dementia care services, from in-home care to hospice care. Some recommendations to study this issue is to do a …

Decolonizing The Map: Indigenous Maps And Gis, Henry Osborne Beimers

All Graduate Theses, Dissertations, and Other Capstone Projects

Indigenous mapping practices have yet to be widely considered by geographers outside of a historical context. In this paper I critique the geographic research paradigm through the lens of settler colonial and critical cartographic theory. I present evidence for the value of Indigenous mapping practices through a historical-critical GIS analysis of two Indigenous maps, and a creation of a story map to present those results. Finally, I suggest future routes to integrate digital mapping and Indigenous mapping practices, for pedagogy, and for preserving cultural resources, language, land, and traditional Indigenous knowledge.

Investigating Anxiety-Like Behavior As A Non-Motor Side Effect Of Deep Brain Stimulation Of The Subthalamic Nucleus In A Parkinsonian Rat Model, Carter Mulder

All Graduate Theses, Dissertations, and Other Capstone Projects

Parkinson’s disease (PD) is estimated to impact nearly 10 million people globally and is estimated to increase in the future. PD is a progressive neurodegenerative disease that worsens through continuous cell death of dopaminergic neurons. This cell death can create motor symptoms such as bradykinesia, tremor, and muscular rigidity. Subthalamic nucleus deep brain stimulation, STN DBS, is a surgical intervention which places stimulating electrodes in the STN greatly improving motor symptoms. However, STN DBS has been reported to possibly influence non-motor symptoms such as anxiety both acutely and long-term, which decreases the quality of life for those with PD. We …

Comparison Of Particulate Load & Characterization In Drug Coated Balloons, Ryan Rykhus

Dissertations and Theses

Peripheral artery disease (PAD) is a disease that affects over 200 million patients worldwide and results in a narrowing of the blood vessels in the lower limbs that is caused by plaque buildup and chronic inflammation. The standard of care for treating this disease is the use of a drug-coated balloon (DCB) to open up the artery through the dilation of the vessel with the balloon and to deliver paclitaxel which prevents the vessel from narrowing after the procedure. In the United States, these DCBs are only approved by the FDA to be used in the artery segments above the …

Author Bios, Glssj Editors

The Great Lakes Social Studies Journal

None

In The Attic Of A Barn, Hunter Pylant

Electronic Theses and Dissertations, 2020-2023

I create wooden and metal sculptures that are abstractions of old memories that examine, celebrate, and embody my rural culture, upbringing, and heritage. I aim to honor my family's memory and keep their passion for craft alive through working with the tools that have been passed down from them. When I find myself struggling in life I always look to my personal history to find answers. I am reminded of my family's rural and military backgrounds and of the tradespeople from my family: carpenters, blacksmiths, farmers, and soldiers. Through their chosen trades and tools, generations from my family were able …

Crossed: Strength In Unity And Connection, Dillon Williams

Electronic Theses and Dissertations, 2020-2023

It is only through the strength of bonds that we can overcome evil. In Crossed, these bonds are tested as Calum and Dmitri are forced to duel for their lives. The film explores the themes of indoctrination, belief, the power of friendship, and never giving up on the people you care about. The accompanying paper explores how these themes are integral to who we are. I then explore the process of producing animation utilizing cutting-edge mediums and how these mediums can allow us to create animation in an entirely new way.

Multiomic Hypotheses Underlying Behavioral Manipulation Of Camponotus Floridanus Ants By Ophiocordyceps Camponoti-Floridani Fungi, Ian Will

Electronic Theses and Dissertations, 2020-2023

Parasitic manipulation of host behavior lies at the intersection of disease, animal behavior, and coevolutionary processes. In many of these interactions, the underpinning biology is brought into sharp focus as they are obligate relationships, under strong selection to bring about specific changes in host behavior that determine if the parasite will transmit or die. However, experimental and molecular techniques to understand these interactions are still developing and identification of the mechanisms of manipulation is a primary goal in the field. As such, we investigated host-parasite interactions between Camponotus floridanus (Florida carpenter ant) and Ophiocordyceps camponoti-floridani (Florida zombie ant fungus) from …

Uncooled Microbolometer Imaging Systems For Machine Vision, Robert Grimming

Electronic Theses and Dissertations, 2020-2023

Over the last 20 years, the cost of uncooled microbolometer-based imaging systems has drastically decreased while performance has increased. In the simplest terms, the figure of merit for these types of thermal detectors is given in terms of the τ-NETD product, the combination of the thermal time constant and the noise equivalent temperature difference. Considering these factors, optimal system design parameters are investigated to maximize visual information content. This dissertation focuses on improving scene information in the longwave infrared (LWIR) spectrum that has had its validity and quality degraded by noise, blur, and reflected radiance. Taken together, noise and blur …

Introductory Guide To Ancient Greek Civilization, Helmut G. Loeffler

Open Educational Resources

No abstract provided.

The Effect Of Audiovisual And Written Interactivity On Teacher-Candidates' Application Of Instructional Support Practices For English Learners In An Online Tesol Course, Sophie Cuocci

Electronic Theses and Dissertations, 2020-2023

With the increased number of English learners in the United States, teacher candidates need to be prepared to address their needs in their future classrooms. Teacher preparation programs around the nation are continuously exploring solutions to better develop teacher candidates' skills. Simultaneously, the rise in popularity of online education has pushed universities to identify and integrate technology tools which best promote students' learning. This study, connecting both challenges, aims to identify which type of interactivity promoted by technology, in an undergraduate online teaching English for speakers of other languages (TESOL) course, most benefits pre-service teachers in their ability to apply …

Financial Sustainability Of Florida Cities: Comparative, Retrospective Modeling For Prospective Municipal Financial Health, Terry Henley

Electronic Theses and Dissertations, 2020-2023

The Great Recession produced rising debt, deficits, and exposed vulnerabilities for municipalities in a globalist economy. The two-month COVID recession in 2020 accelerated these burdens; a lagging downturn recently added pressures of reduced economic activity, record inflation, and rising costs in 2022. This dissertation studies how local financial sustainability (FS) and financial condition (FC) approaches can work in concert towards a set of indicators with internal and external categorization to explain municipal financial health (MFH). Unassigned fund balance plus select formal stabilizations measure MFH, are conceptually supported in having retrospective (FC) and prospective (FS) value as an intergenerational resource and …

Talent Jet, Sai Siddharth Murakonda

All Capstone Projects

In today's world, finding a job is like a rat race in every professional field. The scenario is such that finding jobs that fit the skill sets and interests takes much work for job seekers. On the other side, recruiters face similar challenges in finding the finest candidate to match their requirements.

Talent jet is a website with unique ingredients to solve all these challenges. Talent jet provides an easy and convenient search application for job seekers to find their desired job and recruiters to find suitable candidates. Talent jet will provide a platform where job seekers and recruiters can …

Artificial Intelligence's Impact On Social Engineering Attacks, Sowjanya Manyam

All Capstone Projects

This research paper aims to explore the concept of social engineering attacks and the impact of artificial intelligence on them. Security threats posed by Social Engineering have escalated significantly in recent years. Despite the availability of advanced security software and hardware mechanisms, a vulnerability still exists in the organization's or individual's defense system. In this paper we look at types of social engineering attacks and the basic techniques used by attackers will be described. The primary areas of study are how AI impacts social engineering and is used to detect and prevent social engineering attacks. The application of automated systems …

Lecture: 2022 Sumner Canary Memorial Lecture: Textualism’S Political Morality, Honorable Neomi Rao

Case Western Reserve Law Review

No abstract provided.

Classification Accuracy Of The Quick Interactive Language Screener For Preschool Children With And Without Developmental Language Disorder, Amy Pace, Maura Curran, Amanda Owen Van Horne, Jill De Villiers, Aquiles Iglesias, Roberta Michnick Golinkoff, Mary S. Wilson, Kathy Hirsh-Pasek

Philosophy: Faculty Publications

This research examined the classification accuracy of the Quick Interactive Language Screener (QUILS) for identifying preschool-aged children (3;0 to 6;9) with developmental language disorder (DLD). We present data from two independent samples that varied in prevalence and diagnostic reference standard.

Brilliance And Blindspots: New Light On C.S. Lewis's The Four Loves, Jason Lepojärvi

Faculty Publications - George Fox School of Theology

This paper is a critical re- evaluation of C.S. Lewis’s classic study of Christian love, The Four Loves (1960) that celebrated its 60th anniversary in 2020. After discussing important and neglected differences between the celebrated book and the largely forgotten radio talks which predate it, the paper asks and answers three important questions: Are there really four loves? What is the definition of love itself? What exactly is Charity? Lewis’s answers to these questions are more eclectic than is generally assumed. The paper offers an appreciative rereading of The Four Loves that seeks to correct or at least challenge a …

Small Interfering Rna (Sirna)-Based Therapy, Inderbir S. Padda, Arun U. Mahtani, Mayur S. Parmar

HPD Articles

No abstract provided.

Sodium-Glucose Transport Protein 2 (Sglt2) Inhibitors, Inderbir S. Padda, Arun U. Mahtani, Mayur S. Parmar

HPD Articles

No abstract provided.

The Secret Lives Of Freeports: An Analysis Of The Regulation Of Freeports And The Illicit Antiquities Inside, Daniela Tanico

Fordham International Law Journal

No abstract provided.

Reclamation, Laura Day Webb

MA Projects

This exhibition will take the form of a group show of African artists who weave
/="/">cultural heritage with the contemporary, to challenge Western perceptions of African art and culture. Artists Wole Langunju (Nigeria), Prudence Chimutuwah (Zimbabwe), Lincoln Mwangi (Kenya), Moira Bushkimani (Kenya), and Angèle Etoundi Essamba (Cameroon) are confirmed to participate. In addition to the contemporary works by these artists on display, two Nigerian Gèlèdé masks have been generously loaned from the private collection of Olusanya Ojikutu, one from the early 20th century and, the other, whose dating is undetermined. In showcasing these works in tandem, the exhibition creates …

Anti-Art In Postwar Korea And Japan, Emma Patterson

MA Projects

Emerging from the traumatic devastation of World War II and the economic upheaval that followed, artists in Japan and South Korea adopted similar creative strategies and addressed parallel themes in their artistic responses to the postwar period. Anti-Art in Postwar Korea and Japan brings together artists from the two nations—which share a complex socio-political history—to introduce a new lens through which to understand contemporary East Asian art. Seung-taek Lee, Ha Chong-Hyun, Kim Tschang-Yeul, Lee Ufan, and Nobuo Sekine were few of a number of Korean and Japanese artists who developed comparable practices across the media of painting, sculpture, installation, and …

Fpi Art Initiative: A Romanian Perspective, Through The Looking Glass, Francesca Popescu

MA Projects

The FPI (Francesca Popescu Ife) Art Initiative is a curatorial business that focuses on creating pop-up exhibitions featuring emerging and mid-career artists from countries that are not as widely represented in New York or other major art markets. The foundation of this company is to form partnerships with real estate, hospitality, and public venues to host curated pop-up exhibitions throughout New York City and the Hamptons with future goals to expand nationally. The objective is to showcase artwork within a home environment where individuals and collectors interested in art and design can view and discover new artists exhibited within a …

Za'a Demi-Fine Jewelry: Cultural Representation Through The Use Of Wearable Crafts, Maria Canedo Gomez Ortigoza

MA Projects

Za'a is an e-commerce demi-fine jewelry brand that gives its wearer the ability to explore, connect and give back to indigenous Latin American cultures. Za'a pieces are made with 14k gold, sterling silver, vermeil (solid gold electroplated silver), and semi-precious gemstones while incorporating traditional craftsmanship; incorporating elements such as woodcarving, embroidery, and painting. What makes Za'a's products unique is that they are designed and fabricated in conjunction with the communities, ensuring fair and ethical practices. This close collaboration turns the pieces into a cultural bridge of communication, an exchange of ideas, and an appreciation between consumers and the indigenous communities. …

How Nfts Are Driving The Latest Evolution Of Art From Physical To Digital In A Pandemic Age., Isabel Dominguez De Haro

MA Theses

Prior to 2014, the art industry did not know a lot about NFTs and the benefits of
blockchain technology. That is because when the technology was created in 2008,
it had nothing to do with art. In fact, it was primarily developed as a way to
decentralize a broken financial system.1 And, even when the art industry began
successfully using the technology in 2017, it was the digital art world and not
traditional artists, galleries, auction houses, or dealers who first recognized the
benefit of using digital tokens to represent ownership of a unique asset. So why
now are NFTs …