Digital Commons Network^™

Are Covid-19 Vaccine Boosters Needed? The Science Behind Boosters, Rachel M. Burckhardt, John J. Dennehy, Leo L. M. Poon, Linda J. Saif, Lynn W. Enquist

Publications and Research

Waning vaccine-induced immunity coupled with the emergence of SARS-CoV-2 variants has led to increases in breakthrough infections, prompting consideration for vaccine booster doses. Boosters have been reported to be safe and increase SARS-CoV-2-specific neutralizing antibody levels, but how these doses impact the trajectory of the global pandemic and herd immunity is unknown. Information on immunology, epidemiology and equitable vaccine distribution should be considered when deciding the timing and eligibility for COVID-19 vaccine boosters.

Congress's Commissioners, Brian Feinstein, M Henderson

Articles

No abstract provided.

Delegation Of Powers: A Historical And Functional Analysis, Richard Epstein

Articles

No abstract provided.

Property Law For The Ages, Michael Pollack, Lior Strahilevitz

Articles

No abstract provided.

The Anchor Index, Hope College Archives And Special Collections

Newspaper Indexes

This index contains listings of articles in The Anchor. The Anchor is a newspaper put out by Hope College students. It contains articles written by students about Hope College events, people, issues, etc. Note: This is a rough index. It contains tens of thousands of references and was prepared by past and present volunteer staff.

Entrepreneurial Identity In Us Book Publishing In The Twenty-First Century, Rachel Noorda

English Faculty Publications and Presentations

Entrepreneurship underpins many roles within the publishing industry, from freelancing to bookselling. Entrepreneurs are shaped by the contexts in which their entrepreneurship is situated (social, political, economic, and national). Additionally, entrepreneurship is integral to occupational identity for book publishing entrepreneurs. This Element examines entrepreneurship through the lens of identity and narrative based on interview data with book publishing entrepreneurs in the US Book publishing entrepreneurship narratives of independence, culture over commerce, accidental profession, place, risk, (in)stability, busyness, and freedom are examined in this Element.

Strategic Plan 2021-2027, Tennessee. Wildlife Resources Agency

Strategic Plan 2021-2027

This Strategic Plan strives to anticipate and balance the needs of the wildlife and the public, and to develop strategies that will protect, enhance, and effectively manage our wildlife resources over the next six years.

Racial Bias In Algorithmic Ip, Dan L. Burk

Minnesota Law Review Headnotes, Vols. 94-106 (2009-2022)

No abstract provided.

Association Between Race/Ethnicity And Covid-19 Disease Outcomes In The United States: A Qualitative Systematic Review Of The Literature, Jacob Smith

MEDI 9331 Scholarly Activities Clinical Years

Background/Objective: As studies have shown disparities in coronavirus disease-19 prevalence and severity, we sought to evaluate differences in outcomes of acute SARS-CoV-2 infection by race/ethnicity.

Design: Systematic review

Data Source: Studies from PubMed were included.

Review methods: Articles published in English language from January 1, 2019 through March 22, 2020. Studies included were observational studies that examined racial or ethnic disparities in SARS-CoV-2 infection outcomes in the United States. One reviewer performed data extraction.

Results: Out of a possible 1,944 articles, 99 observational studies (82 individual-level and 17 population-level) were included. Differential rates of hospitalization or otherwise severe illness …

Maternal Autonomy Support And Children’S Social Competencies, Academic Skills, And Persistence: Social Determinants And Mediation, Chang Su-Russell, Luke Russell

Faculty Publications - Family and Consumer Sciences

Drawing on self-determination theory, family stress theory, and the social determinants of health framework, the current study sought to evaluate direct and indirect relationships among socioeconomic status (maternal education and income), parenting stress, autonomy supportive parenting behavior, and children’s positive outcomes (e.g., social competences, academic skills, and persistence) using a racially diverse sample from low-income backgrounds. Using data on 2,233 children collected at birth (T1), age 5 (T2) and age 9 (T3) as part of the Fragile Families and Child Wellbeing study, a structural equation model was tested in MPlus. Associations among main constructs were tested in a single structural …

Kinship Care In Pennsylvania: Creating An Equitable System For Families, Heidi Redlich Epstein, Lucy Johnston-Walsh, Jennifer Pokempner, Kathleen Creamer, Karissa Phelps

Faculty Scholarly Works

Family connection provides one of the most important contributions to the development and identity of children. A child’s family connections help them grow and thrive, provide them identity and security, and are a critical link to culture and traditions.

When experiencing difficult times, family members can support each other in ways no one else can, with the shared goal of keeping the family intact and connected.

When a child’s life is disrupted, calling on the support of family is custom in most communities and can be a great source of comfort for both children and the family. This is especially …

Health Ai For Good Rather Than Evil? The Need For A New Regulatory Framework For Ai-Based Medical Devices, Sara Gerke

Faculty Scholarly Works

Artificial intelligence (AI), especially its subset machine learning, has tremendous potential to improve health care. However, health AI also raises new regulatory challenges. In this Article, I argue that there is a need for a new regulatory framework for AI-based medical devices in the U.S. that ensures that such devices are reasonably safe and effective when placed on the market and will remain so throughout their life cycle. I advocate for U.S. Food and Drug Administration (FDA) and congressional actions. I focus on how the FDA could - with additional statutory authority - regulate AI-based medical devices. I show that …

Developing An Enhanced 7-Color Multiplex Ihc Protocol To Dissect Immune Infiltration In Human Cancers., Zhaoyu Sun, Richard Nyberg, Yaping Wu, Brady Bernard, William L. Redmond

Articles, Abstracts, and Reports

The TSA Opal multiplex immunohistochemistry (mIHC) protocol (PerkinElmer) has been used to characterize immune infiltration in human cancers. This technique allows multiple biomarkers to be simultaneously stained in a single tissue section, which helps to elucidate the spatial relationship among individual cell types. We developed and optimized two improved mIHC protocols for a 7-color panel containing 6 biomarkers (CD3, CD8, CD163, PD-L1, FoxP3, and cytokeratin (CK)) and DAPI. The only difference between these two protocols was the staining sequence of those 6 biomarkers as the first sequence is PD-L1/CD163/CD8/CK/CD3/FoxP3/DAPI and the second sequence is FoxP3/CD163/CD8/CK/CD3/PD-L1/DAPI. By comparing PD-L1/FoxP3 staining in …

Physicochemical And Functional Property Modification Of Myofibrillar Protein By Phenolic Compounds Under Oxidative Stress, Anqi Guo

Theses and Dissertations--Animal and Food Sciences

Polyphenol-rich spices and extracts of phenolic compounds are widely utilized in meat processing to modify product flavors. Chemically, polyphenols are reactive with myofibrillar protein (MP), the most functional fraction of all muscle proteins responsible for texture development in comminuted meat products. Such protein–polyphenol interaction is prevalent under oxidative conditions that are common in meat processing. As a large group of phytochemicals with diverse structures, phenolic compounds are known to interact with MP with varying efficacies. Yet, the structure-function relationship of polyphenols in eliciting modification of MP is poorly understood. The overall objective of this dissertation research was to elucidate the …

The Effect Of Oil Type, Oil Quality, Vitamin E, And Phytase Supplementation On Broiler Performance, Apparent Nutrient And Energy Utilization, And The Fatty Acid Profile Of Fat And Liver In Broiler Chickens, Richard A. Adefioye

Theses and Dissertations--Animal and Food Sciences

Two experiments were conducted to examine the effects of oil type, oil quality, phytase, and vitamin E (VE) supplementation in broiler chickens. Experiment 1 used 378-day-old male by-product Cobb breeder chicks with 9 treatments, 7 replicates, and 6 birds per replicate, structured as a 2x2x2+1 factorial arrangement of treatments for 14 days. The first 8 treatments were based on a marginally non-phytate phosphorus (NPP) deficient diet (0.31%), while treatment 9 was a positive control (PC) diet with adequate NPP levels (0.45%). There were 2 levels of phytase (0 vs 1000 FTU/kg), 2 levels of oil quality (fresh soy oil; peroxide …

Animal And Plant Protein Oxidation: Chemical And Functional Property Significance, Youling L. Xiong, Anqi Guo

Animal and Food Sciences Faculty Publications

Protein oxidation, a phenomenon that was not well recognized previously but now better understood, is a complex chemical process occurring ubiquitously in food systems and can be induced by processing treatments as well. While early research concentrated on muscle protein oxidation, later investigations included plant, milk, and egg proteins. The process of protein oxidation involves both radicals and nonradicals, and amino acid side chain groups are usually the site of initial oxidant attack which generates protein carbonyls, disulfide, dityrosine, and protein radicals. The ensuing alteration of protein conformational structures and formation of protein polymers and aggregates can result in significant …

Investigations Into The Genetics Of Mixed Pathologies In Dementia, Adam Dugan

Theses and Dissertations--Epidemiology and Biostatistics

Alzheimer’s disease (AD) is an irreversible, progressive brain disorder that leads to a loss of memory and thinking skills. While tremendous progress has been made in our understanding of the genetics underlying AD, currently known genetic variants explain only approximately 30% of the heritable risk of developing AD. One hurdle to AD research is that it can only be definitively diagnosed at autopsy, making cruder, clinic-based diagnoses more common. In recent years, several brain pathologies that mimic AD’s clinical presentation have been identified including brain arteriolosclerosis, hippocampal sclerosis (HS), and, most recently, limbic-predominant age-related TDP-43 encephalopathy (LATE). It has become …

Unbecoming Adversaries: Natural Resource Federalism In Wyoming, Tara Kathleen Righetti, Robert B. Keiter, Jason Robison, Temple Stoellinger, Sam Kalen

Utah Law Faculty Scholarship

Wyoming’s unique cultural and physical landscape fostered dynamic federalism relationships that have oscillated between adversarial and cooperative. Too often, though, the State and its federal and tribal counterparts have found themselves in the role of unbecoming adversaries. As current and former natural resources faculty members at the University of Wyoming (UW) College of Law, we are privileged to offer a retrospective on this subject upon the law school’s centennial. In 2021, the State is facing new and daunting challenges that are straining its core industries and budget, including economic changes associated with the COVID-19 global pandemic and rapidly transforming energy …

Is Obesity A Manifestation Of Systemic Racism? A Ten‐Point Strategy For Study And Intervention, Daniel G. Aaron, Fatima Cody Stanford

Utah Law Faculty Scholarship

In the recent past, there has been rising attention to systemic racism. The ensuing discussions have largely focused on COVID-19 and policing. Despite long-standing disparities in obesity across racial and ethnic groups and obesity’s important role in COVID-19 disparities, there has been minimal attention to whether obesity itself could be a manifestation of systemic racism. Nor has there been serious policy attention dedicated to alleviating obesity and its disproportionate burden on BIPOC (Black, Indigenous, and People of Color). We discuss whether obesity’s disproportionate harms to BIPOC may be attributed to systemic racism, and we provide a ten-point strategy for studying …

Farming With Trees: Reforming U.S. Farm Policy To Expand Agroforestry And Mitigate Climate Change, Lingxi Chenyang, Andrew Currie, Hannah Darrin, Nathan Rosenberg

Utah Law Faculty Scholarship

Agroforestry systems have enormous potential to mitigate climate change. These systems incorporate trees and shrubs into agricultural production, increasing both soil carbon sequestration and the amount of carbon stored in biomass. Even the most conservative estimates find that agroforestry sequesters two to five times more carbon per acre than the most effective—and better known—climate-friendly practices for annual crops, such as no-till agriculture and cover crops. Agroforestry also offers substantial environmental and economic benefits: clean water, reduced fertilizer and pesticide use, greater resiliency, and higher profitability per acre. Yet there are significant legal and policy barriers to its expansion in the …

The Day I Left, Nidaa Aljabbarin

Intertext

No abstract provided.

Scalable Approaches For Auditing The Completeness Of Biomedical Ontologies, Fengbo Zheng

Theses and Dissertations--Computer Science

An ontology provides a formalized representation of knowledge within a domain. In biomedicine, ontologies have been widely used in modern biomedical applications to enable semantic interoperability and facilitate data exchange. Given the important roles that biomedical ontologies play, quality issues such as incompleteness, if not addressed, can affect the quality of downstream ontology-driven applications. However, biomedical ontologies often have large sizes and complex structures. Thus, it is infeasible to uncover potential quality issues through manual effort. In this dissertation, we introduce automated and scalable approaches for auditing the completeness of biomedical ontologies. We mainly focus on two incompleteness issues -- …

Evaluation Of Liquid Ice Melting Additives For Winter Maintenance Applications, Erin Lammers-Staats

Theses and Dissertations--Civil Engineering

Winter weather can often pose difficulties for transportation agencies as they work to clear roads of snow and ice quickly so that motorists can travel safely and efficiently. Kentucky has made efforts to maximize efficiency within its winter maintenance program by focusing on optimized equipment usage and personnel time management. This study’s objective was to evaluate novel anti-icers and calculate how their performance compared to the current performance of brine and calcium chloride mixture. New brine additives claim to offer better results, but there is very little guidance about how to systematically evaluate new anti-icers. The author developed a testing …

Pandemics, Paid Sick Leaves, And Tax Institutions, Alex Zhang

Loyola University Chicago Law Journal

The COVID-19 pandemic is currently ravaging the world, and the United States has been largely unsuccessful at containing the coronavirus. One long-standing policy failure stands out as having exacerbated the pandemic in our country: the lack of a national mandate of paid sick leaves, without which workers face financial and workplace-cultural pressures to attend work while sick, thus spreading the virus to their fellow employees and the public at large.

This Article provides the blueprint for a national, subsidized mandate of paid sick leaves and two additional insights about our tax institutions as mechanisms of effectuating broader societal goals. It …

Privacy In Pandemic: Law, Technology, And Public Health In The Covid-19 Crisis, Tiffany C. Li

Loyola University Chicago Law Journal

The COVID-19 pandemic has caused millions of deaths and disastrous consequences around the world, with lasting repercussions for every field of law, including privacy and technology. The unique characteristics of this pandemic have precipitated an increase in use of new technologies, including remote communications platforms, healthcare robots, and medical AI. Public and private actors alike are using new technologies, like heat sensing, and technologically influenced programs, like contact tracing, leading to a rise in government and corporate surveillance in sectors like healthcare, employment, education, and commerce. Advocates have raised the alarm for privacy and civil liberties violations, but the emergency …

We All Bleed Red: Dismantling The Discriminatory Gay Blood Ban In The Era Of Bostock, Rohan Keith Andresen

Loyola University Chicago Law Journal

No abstract provided.

Undergraduate Bulletin 2021-2022, Cuny John Jay College

College Bulletins

Covers academic year 2021-2022

Safety As A Criterion For Faculty Evaluation, Emily Faulconer

Publications

Faculty evaluations, whether for annual review, promotion, contract renewal, tenure, or other purposes, commonly cover three broad areas—teaching, scholarship, and service—with weighting that can vary based on the institution, college, department, and individual. Many faculty, especially in STEM fields, have teaching, research, and service roles that come with chemical, physical, or biological hazards. These faculty members would not likely deny safety as a responsibility. In these roles, faculty may be asked to teach safety concepts, supervise or perform work with instrumentation, manage chemical wastes, or prepare paperwork required under OSHA’s Laboratory standard (e.g., standard operating procedures).

The Critical Need For A Culturally Sensitive Suicide Risk Assessment Instrument For American Indian And Alaska Native Youth, Courtney E. Shaw

All Graduate Theses, Dissertations, and Other Capstone Projects

Objective: This systematic literature review was conducted to better understand why there has been a significant increase in America Indian/Alaska Native (AI/AN) youth suicides in tribes across the United States today. The intent of this review is to understand key issues surrounding the increasing numbers of AI/AN youth with suicide ideation, plans, and attempt in order to be able to answer the following clinical question: Is there a valid and reliable culturally sensitive assessment tool designed to recognize at-risk AI/AN youth presenting for primary care? If not, what are key aspects to consider for developing an instrument that could …

Younger Hmong People’S Willingness To Communicate About Depression, Wa Yang

All Graduate Theses, Dissertations, and Other Capstone Projects

This research examines the underlying issues about mental illness, particularly depression within the Hmong community. Previous scholars have focused on the Hmong culture’s origins, mental health status of Hmong refugees arriving in the United States, martial roles and mental health on Hmong females, and comparisons of Hmong traditional healing and Westernized medicine. These studies intersect in fields including psychology, medicine and public health, Hmong history, and social work. However, one missing component to this body of scholarship has been communication. Thus, my study focused on younger Hmong people’s willingness to communicate about depression within their families. Specifically, I conducted semi-structured …